Epigenetics - basic mechanisms and disease – Karl Ekwall's research group

We are studying epigenetic modification mechanisms in fission yeast and human cell lines as model systems. In our basic research we focus on how these mechanisms contribute to cell cycle, cell differentiation and cellular quiescence. We also carry out applied collaborative cancer epigenetic projects. We have extensive expertise in chromatin analysis by genome-wide methods using our cellular model systems.

Part of the Department of Biosciences and Nutrition

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Publications
Staff and contact

Publications

Selected publications

Article: CHROMOSOME RESEARCH. 2023;31(2):14
An essential role for the Ino80 chromatin remodeling complex in regulation of gene expression during cellular quiescence
Zahedi Y; Zeng S; Ekwall K
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(4):1793
The Role of Non-Catalytic Domains of Hrp3 in Nucleosome Remodeling
Dong W; Prasad P; Lennartsson A; Ekwall K
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020;21(23):E9022-9022
High-Throughput Flow Cytometry Combined with Genetic Analysis Brings New Insights into the Understanding of Chromatin Regulation of Cellular Quiescence
Zahedi Y; Durand-Dubief M; Ekwall K
Article: EPIGENETICS AND CHROMATIN. 2019;12(1):45
Leo1 is essential for the dynamic regulation of heterochromatin and gene expression during cellular quiescence
Oya E; Durand-Dubief M; Cohen A; Maksimov V; Schurra C; Nakayama J-I; Weisman R; Arcangioli B; Ekwall K

Staff and contact

Group leader

Karl Ekwall
Professor | Docent
Telephone +46852481039
E-mail karl.ekwall@ki.se

All members of the group

Olov Bygren
Affiliated to Research
E-mail lars.olov.bygren@ki.se
Karl Ekwall
Professor | Docent
Telephone +46852481039
E-mail karl.ekwall@ki.se
Shengyuan Zeng
Phd Student
E-mail shengyuan.zeng@ki.se