Continuing professional development (CPD)
The aim of these educations is to follow the legal requirements for maintenance and demonstration of competence, and to facilitate the implementations of the 3R’s in routine animal work.
It is also a part of Comparative Medicine’s career ladder, outlining opportunities for competence development and for animal technicians at KI to advance to other positions.
Continued Professional Development (CPD) seminars
All CPD seminars are free of charge. To those attending, a CPD certificate will be provided. According to the Directive 2010/63/EU and SJVFS 2017:40 (L150), all persons working with research animals are required to maintain their LAS competence via CPD activities.
Staff carrying out procedures on animals (Function A) should accomplish at least 10 hours of CPD activities/year; and persons designing scientific procedures or projects involving animals (Function B), should accomplish at least 15 hours of CPD activities/year.
To register please follow the appropriate link. Exact location will be announced later, as it depends on the total number of registered participants.
The Reproducibility Crisis in Animal Research and What Can Be Done About It
There is a growing concern about the reliability of animal studies. While many factors can contribute to this problem, a main reason is generally considered to be the failure of preclinical animal models to predict clinical efficacy.
- Learn about the causes for the reproducibility crisis in animal research.
- Understand what solutions can be used to address this problem.
Merel Ritskes-Hoitinga, Professor in Evidence-Based Laboratory Animal Science, SYRCLE, Radboud University Medical Center, Nijmegen, The Netherlands.
Date: Friday 8 March, 2019. Time: 9-10.
Registration: Register here by 21 February.
Experimental Design of Animal Studies and the Reproducibility Crisis
Too many pre-clinical research papers are presenting results which turn out to be irreproducible. This is leading to a substantial waste of animals and scientific resources. But there is one simple way in which reproducibility could be improved. Scientists could use randomized block experimental designs instead of completely randomized designs.
- Learn about the principles of experimental design of animal studies.
- Discuss the merits of randomized block designs.
Speaker: Michael FW Festing, Ph.D., D.Sc., CStat., Consultant, Retired from MRC, Toxicology Unit, U.K.
Date: Wednesday 13 March, 2019. Time: 15.00-16.00
Registration: Register here by 26 February.
Humane Endpoints in Animal Experimentation: the Least We Can Do
A small but significant percentage of lab animals are exposed to high levels of pain and distress. There is a moral, legal and also scientific obligation to minimize suffering. The assessment of humane endpoints, both when designing and undertaking animal studies, can be one of the most difficult tasks facing experimenters and animal care staff.
In this seminar we will discuss the topic of humane endpoints in the context of research objectives, clinical and preclinical markers, use of scoring sheets and training needs.
- Increase awareness on the implementation of humane endpoints in animal studies that involving high levels of pain & distress.
- Learn about animal health & welfare monitoring, critical clinical signs and usefulness of score sheets.
Speaker: Emeritus Prof. Coenraad Hendriksen, Department of Animals in Science and Society; 3R Centre Utrecht Life Sciences, Utrecht, The Netherlands.
Date: Wednesday 20 March, 2019. Time: 15.00-16.00
Registration: Register here by 5 March.
Why and How Should We Talk About Animal Research to the Public
For many years, animal researchers chose not to speak out about their work, leading to misinformation and a lack of public understanding. This talk will explain why the Concordat on Openness on Animal Research was developed in UK in 2014 and how it is helping to improve public understanding.
- Hear about the UK’s experience of being more open about animal research.
- Understand the benefits of public communication on this topic.
Speaker: Wendy Jarrett, Chief Executive, Understanding Animal Research, London, U.K.
Date: Wednesday 27 March, 2019. Time: 15-16.
Registration: Register here by 12 March
Cage-Side Assessment of Pain in Research Animals
Speaker: Matthew Leach, Ph.D., Lecturer, Natural and Environmental Sciences, Newcastle University, U.K.
Date: Thursday 11 April, 2019. Time: 13-14.
Registration: Register here by 27 March
Experimental Surgery - What’s Different About Rodents?
High standards of surgical technique in rodents will reduce the likelihood of post-operative complications, which are known to have significant impact on experimental data and animal welfare.
- Why and how to achieve aseptic technique.
- Special considerations about surgery in rodents.
Speaker: Emeritus Professor Paul A Flecknell, MA, VetMB, PhD, DECLAM, DLAS, DECVA, (Hon) DACLAM, FRSB, (Hon) FIAT, (Hon) FRCVS Newcastle University, U.K.
Date: Friday 24 May, 2019. Time: 14-15.
Registration: Register here by 27 March.
Therioepistemology – the Study of How Knowledge is Gained from Animal Research
Speaker: Assoc. Prof. Joseph Garner, Comparative Medicine, Stanford University, U.S.
Date: Friday 28 June, 2019. Time: 9-10.
Registration: Register here by 13 June.
Phenotyping of genetically engineered mice (2 ECTS)
The course teaches how genetically engineered mice can be phenotyped in a strategic way.
The course aims to teach the basic biology of the laboratory mouse in its context of genetically modified animal models. It will provide an overview of available endpoints, and of the various types of results obtained from different analyses and highlight their complementary value as well as limitations.
The course is on the doctoral level (2.0 ECTS) but open for post docs and researchers. Target audience: any person who is or will be involved with mouse studies.
Course start date
Dates will come.
- Systematic phenotype analysis
- Transgenesis methodology and breeding
- Selection of controls
- Mouse biology, strain differences and characterization
- Necropsy techniques, perfusion fixation
- Post mortem tissue preparation for histology
- Imaging technique
Why is the course important for KI's researchers?
Phenotyping is a broad term that encompasses the integrated recording of a set of biological parameters both on clinical and tissue level, to characterize a condition in an organism. Phenotyping is typically useful to characterize genetically engineered organisms. Successful integrated phenotyping of genetically engineered mice helps researchers identify areas of interest associated with genetic condition, adding to our understanding of gene function and regulation.
The course is free for PhD students registered at KI. For all other participants and PhD students from other universities the course fee is 8000 SEK excluding INDI.
The course location is Karolinska Institutet, Campus Solna.
Leader for the course is Raoul Kuiper, PhD, DVM Dipl. ECVP Pathology, Karolinska Institutet.
Hands on workshop: Refine your practical skills for basic animal work
Refresh and refine your practical skills for basic animal work. Key contents are handling and immobilization techniques, dosing (IP, SC, IV), sampling (blood collection) and euthanasia. (EU 3.2, 6.2 and 8)
Fee 500 SEK (excluding INDI)
Application for an animal research project license
Learn how to apply to the animal ethics committee for a project license, we will discuss hints and tips for applicants. (EU 11)
No dates yet for 2018
Hands-on training at Comparative Medicine Learning Lab
The Learning lab offers supervised training sessions in small groups to improve your practical skills in laboratory animal science. See "Hands on workshop: Refine your practical skills for basic animal work".
Learning Lab for rent
Are you looking for a small lecture room that is centrally situated at KI Campus Solna, and that is available for online reservation? Or maybe you are interested in a large and spacious lab, fully equipped for microsurgery in rat and mouse?
The Learning Lab at Comparative Medicine is available for rent for lectures, practical training and research with laboratory animals.
The learning lab can be rented as a:
- lecture room for a maximum of 20 persons
- course lab for a maximum of 16 students
- research lab for short-term and terminal experiments with laboratory animals.
Available equipment (examples):
- slide projector
- projector screen
- stationary computer (PC)
- wireless Internet
- 8 microscopes for use in microsurgery
- gas anesthesia
- basic lab equipment
Licensed animal facility
The Learning Lab is licensed as an animal facility by the Swedish Board of Agriculture and can house mice and rats for up to six weeks. Genetically modified animals are however not allowed.
Mice or rats can be provided from our ethics application for customers who want to perform experiments with surgical techniques.
For lectures: 1150 SEK/day: 8 hours (excl. INDI).
For research and to be used for courses: 1620 SEK/day: 8 hours excl. INDI), alternatively 6700 SEK/week (excl. INDI)
Make a request for a reservation
Log on to Time Edit to make a request for a reservation of Learning Lab. In Swedish: “Beställning Learning Lab”.
Your reservation must be confirmed before you can use the lab.
Please note: All persons entering the Learning Lab are on a 24-hour quarantine before they can enter another animal facility. Persons allergic to laboratory animals shall not enter the Learning Lab.