Projects: Unit of Lung and Airway Research

Th17-associated cytokines and host defense in smokers

This project characterizes the pathogenic role of Th17-associated cytokines in the increased susceptibility to infections that signifies long-term smokers, in particular in those who suffer from chronic obstructive pulmonary disease (COPD) with or without chronic bronchitis.

Financing

  • The Swedish Heart-Lung Foundation
  • ALF

Contact person

Anders Lindén

Professor/senior physician

The IL-36 family of cytokines in chronic obstructive pulmonary disease

This project will assess whether members of the IL-36 family of cytokines are involved in COPD, with and without chronic bronchitis. Additionally, the project will assess the downstream immunologic effects of IL-36 receptor stimulation in structural lung and immune cells.

Financing

  • European Respiratory Society
  • The Swedish Heart-Lung Foundation

Contact person

Melissa Kovach

Affiliated to research

 Cadmium as a pathogenic factor in tobacco smokers

This project explores the pathogenic role of cadmium in the development of COPD, among long-term smokers, in particular the role of cadmium in the distortion of pulmonary host defense.

Financing

  • The Swedish Heart-Lung Foundation
  • ALF

Contact person

Bettina Brundin

Senior lab manager