Health risk assessment of chemicals: Principles and applications

Course dates

November 18-22, 2024
The course starts at 13.00 on November 18 and ends at 11.30 on November 22.

Course location

The course will be given at Karolinska Institutet, Campus, Stockholm, Sweden as an in-person course only. On-line participation will not be possible.

Course Organiser

The course is organised by PARC, Partnership for the Assessment of Risks from Chemicals. https://www.eu-parc.eu/
Local organiser is Institute of Environmental Medicine (IMM), Karolinska Institutet.

Learning outcomes

Upon completion of the course, the participants should be able to:

  • describe the basic concepts and principles of health risk assessment of chemical substances
  • explain how different types of data from in vivo/animal, epidemiological and in vitro studies as well as exposure data are used in risk assessment
  • assess the relevance and reliability of data used in risk assessment
  • derive health based guidance values such as Acceptable Daily Intake (ADI) based on the data
  • reflect on the role of health risk assessment in regulatory decision making

Content

The course will introduce the concepts in risk assessment, e.g. aims of risk assessment, role of risk assessment in risk analysis (risk assessment, risk management, risk communication), different steps in risk assessment (hazard identification, hazard characterisation, exposure assessment, risk characterisation). Different types of data from in vivo/animal, epidemiological and in vitro studies as well as exposure data that are used in risk assessment will be discussed, including assessment of relevance and reliability of the data, and how different kind of evidence is integrated. New approaches and next generation risk assessment will be introduced. The principles on how to derive health-based guidance values such as Acceptable Daily Intake (ADI) and to derive Margins of Safety values based on the data are exercised. The course will provide examples of the role of risk assessment in regulatory decision making and present cases with examples. The course will include lectures, exercises and group assignments. 

Teaching and learning activities

Teaching and learning activities include lectures, exercises and group assignments.

Course programme

Programme

Target group

The training course is addressed to PhD students and researchers as well as participants from authorities who benefit from understanding the principles and applications of health risk assessment of chemicals for their work in PARC or for other research or risk assessment activities. This course is open for both PARC members and non-members, although priority will be given to PARC members.

Course fee

There are no registration fees; however, participants are expected to cover their own travel, accommodation, and any other incidental expenses.

More information at PARC website

For more information visit PARC website https://www.eu-parc.eu/

Course application

Apply here https://survey.ki.se/Survey/39051
Application deadline: 7 June 2024
Accepted participants will be notified after the application deadline.

Course directors

Johanna Zilliacus, Anna Beronius and Annika Hanberg, Institute of Environmental Medicine, Karolinska Institutet.

JZ
Content reviewer:
16-04-2024