Biofabrication and Tissue Engineering (Biofab) Facility

The Biofabrication and Tissue Engineering Facility at Karolinska Institutet (Biofab) offers a diverse range of Micro and Nanostructuring techniques for cell-based applications in the fields of life-science and medicine.

researcher in Micro and nanofabrication core facility

At BioFab, we aim to bridge the gap between engineering and biology at Karolinska Institutet and provide common grounds with respect to suitable material of use of modular design and tunable structures for biomedical purposes.


  • Microfluidics
  • Lab-on-a-chip
  • Biosensors
  • Tissue and organ-on-a-chip
  • Tissue engineering

In-house equipment

  • Spin-coater
  • Collimated UV light
  • Contact angle goniometer
  • Polymer Speed mixer
  • Oven

In-house Micro and Nanofabrication platforms

  • Photolithography
  • Nano reaction injection molding (NanoRIM)
  • Soft lithography

Off-campus Micro and Nanofabrication platforms

  • Photolithography (mask aligner)
  • Electron beam lithography
  • Nanoimprint lithography
  • CNC micro Milling

Device characterisation methods

  • Scanning electron microscopy (SEM)
  • Atomic force microscopy (AFM)
  • Profilometer

List of materials

Glass, silicon, and polymers including different types of thermoplastics, e.g. Poly(methyl methacrylate) (PMMA), Polycarbonate (PC), Polystyrene (PS) and Teflon, thermosets, e.g. off-stoichiometry thiol-ene (OSTE), SU8 and elastomers, e.g. PDMS.

Download comparative overview of common materials used for cell culture devices (pdf)


  • Consultation about the proper choice of material and design with respect to the biological application
  • 3D CAD design
  • Nanofabrication via cleanroom processing
  • Surface energy patterning (tuning hydrophilicity and hydrophobicity)


Price for the in-house tool equipment: 1500 SEK/hour

Facility support: additional 1500 SEK/hour, or on collaborative bases.

For off-campus tools, prices are calculated based on each project.



Karolinska Institutet, Biomedicum, Solnavägen 9, B0911-B0913


If you have any questions or would to like to get access to the facility, contact us:

Volker Lauschke

Associate Professor, Director of Biofab
C3 Department of Physiology and Pharmacology

Reza Zandi Shafagh

Head of Biofab
C3 Department of Physiology and Pharmacology