Jan-Åke Gustafsson

Publikationer
Populärvetenskap och samverkan

Artiklar

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2024;121(13):e2306814121
Activation of ERβ hijacks the splicing machinery to trigger R- loop formation in triple- negative breast cancer
Wang D; Tang M; Zhang P; Yang K; Huang L; Wu M; Shen Q; Yue J; Wang W; Gong Y; Warner M; Dai L; He H; Yang Z; Gustafsson J-A; Zhou S
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023;24(15):12461
Loss of ERβ in Aging LXRαβ Knockout Mice Leads to Colitis
Song X; Wu W; Dai Y; Warner M; Nalvarte I; Antonson P; Varshney M; Gustafsson J-A
Article: BIOCHIMICA ET BIOPHYSICA ACTA - MOLECULAR BASIS OF DISEASE. 2023;1869(6):166755
Estrogen receptor β attenuates renal fibrosis by suppressing the transcriptional activity of Smad3
Cao R; Su W; Sheng J; Guo Y; Su J; Zhang C; Wang H; Tang Y; Chen L; Qiao R; Chen X; Huang X; Zhou Y; Zhu L; Bai Z; Zhang X; Gustafsson J-A; Wan Q; Lan H-Y; Guan Y
Article: TOXICOLOGICAL SCIENCES. 2023;193(2):119-130
Triazole fungicides induce adipogenesis and repress osteoblastogenesis in zebrafish
Thrikawala S; Mesmar F; Bhattacharya B; Muhsen M; Mukhopadhyay S; Flores S; Upadhyay S; Vergara L; Gustafsson J-A; Williams C; Bondesson M
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023;24(6):5867
Estrogen Receptor β4 Regulates Chemotherapy Resistance and Induces Cancer Stem Cells in Triple Negative Breast Cancer
Bano A; Stevens JH; Modi PS; Gustafsson J-A; Strom AM
Article: CELL DEATH AND DISEASE. 2023;14(2):129
Harnessing the reverse cholesterol transport pathway to favor differentiation of monocyte-derived APCs and antitumor responses
Raccosta L; Marinozzi M; Costantini S; Maggioni D; Ferreira LM; Corna G; Zordan P; Sorice A; Farinello D; Bianchessi S; Riba M; Lazarevic D; Provero P; Mack M; Bondanza A; Nalvarte I; Gustafsson J-A; Ranzani V; De Sanctis F; Ugel S; Baron S; Lobaccaro J-MA; Pontini L; Pacciarini M; Traversari C; Pagani M; Bronte V; Sitia G; Antonson P; Brendolan A; Budillon A; Russo V
Article: MICROBIOME. 2022;10(1):160
Estrogen receptor β deficiency impairs gut microbiota: a possible mechanism of IBD-induced anxiety-like behavior
Ma Y; Liu T; Li X; Kong A; Xiao R; Xie R; Gao J; Wang Z; Cai Y; Zou J; Yang L; Wang L; Zhao J; Xu H; Margaret W; Xu X; Gustafsson J-A; Fan X
Article: HEARING RESEARCH. 2022;422:108534
Ablation of Liver X receptor β in mice leads to overactive macrophages and death of spiral ganglion neurons
Song X-Y; Wu W-F; Dai Y-B; Xu H-W; Roman A; Wang L; Warner M; Gustafsson J-A
Article: JBMR PLUS. 2022;6(8):e10657
ERα Signaling in a Subset of CXCL12-Abundant Reticular Cells Regulates Trabecular Bone in Mice
Scheffler JM; Gustafsson KL; Barrett A; Corciulo C; Drevinge C; Pons AMDC; Humeniuk P; Engdahl C; Gustafsson J-A; Ohlsson C; Carlsten H; Lagerquist MK; Islander U
Article: ENDOCRINOLOGY. 2022;163(7):bqac080
Inactivation of AR or ERα in Extrahypothalamic Neurons Does not Affect Osteogenic Response to Loading in Male Mice.
Kim NR; David K; Sommers V; Schollaert D; Deboel L; Ohlsson C; Gustafsson J-Å; Antonio L; Decallonne B; Claessens F; Vanderschueren D; Dubois V
Article: ENVIRONMENT INTERNATIONAL. 2022;164:107250
G protein-coupled estrogen receptor activation by bisphenol-A disrupts the protection from apoptosis conferred by the estrogen receptors ERα and ERβ in pancreatic beta cells
Babiloni-Chust I; dos Santos RS; Medina-Gali RM; Perez-Serna AA; Encinar J-A; Martinez-Pinna J; Gustafsson J-A; Marroqui L; Nadal A
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2022;42(6):719-731
Myeloid LXR (Liver X Receptor) Deficiency Induces Inflammatory Gene Expression in Foamy Macrophages and Accelerates Atherosclerosis
Endo-Umeda K; Kim E; Thomas DG; Liu W; Dou H; Yalcinkaya M; Abramowicz S; Xiao T; Antonson P; Gustafsson J-A; Makishima M; Reilly MP; Wang N; Tall AR
Article: CELL COMMUNICATION AND SIGNALING. 2022;20(1):74
Ahi1 regulates serotonin production by the GR/ERβ/TPH2 pathway involving sexual differences in depressive behaviors
Wang B; Shi H; Ren L; Miao Z; Wan B; Yang H; Fan X; Gustafsson J-A; Sun M; Xu X
Article: FRONTIERS IN MOLECULAR NEUROSCIENCE. 2022;15:1023765
Valproic acid exposure decreases neurogenic potential of outer radial glia in human brain organoids
Zang Z; Yin H; Du Z; Xie R; Yang L; Cai Y; Wang L; Zhang D; Li X; Liu T; Gong H; Gao J; Yang H; Warner M; Gustafsson J-A; Xu H; Fan X
Article: JOURNAL OF AUTOIMMUNITY. 2021;124:102723
Liver X receptor beta deficiency attenuates autoimmune-associated neuroinflammation in a T cell-dependent manner
Bogie JFJ; Vanmierlo T; Vanmol J; Timmermans S; Mailleux J; Nelissen K; Wijnands E; Wouters K; Stinissen P; Gustafsson J-A; Steffensen KR; Mulder M; Zelcer N; Hendriks JJA
Article: MOLECULAR PSYCHIATRY. 2021;26(11):6380-6393
Loss of liver X receptor β in astrocytes leads to anxiety-like behaviors via regulating synaptic transmission in the medial prefrontal cortex in mice
Li X; Zhong H; Wang Z; Xiao R; Antonson P; Liu T; Wu C; Zou J; Wang L; Nalvarte I; Xu H; Warner M; Gustafsson J-A; Fan X
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(33):e2104162118
Drivers and suppressors of triple-negative breast cancer
Wu W; Warner M; Wang L; He W-W; Zhao R; Guan X; Botero C; Huang B; Ion C; Coombes C; Gustafsson J-A
Article: EPILEPSIA. 2021;62(7):1689-1700
Folic acid supplementation rescues valproic acid-induced developmental neurotoxicity and behavioral alterations in zebrafish embryos
Muhsen M; Youngs J; Riu A; Gustafsson J-A; Kondamadugu VS; Garyfalidis E; Bondesson M
Article: ENDOCRINOLOGY. 2021;162(6):bqab045
Testosterone Reduces Body Fat in Male Mice by Stimulation of Physical Activity Via Extrahypothalamic ERα Signaling.
Kim NR; David K; Corbeels K; Khalil R; Antonio L; Schollaert D; Deboel L; Ohlsson C; Gustafsson J-Å; Vangoitsenhoven R; Van der Schueren B; Decallonne B; Claessens F; Vanderschueren D; Dubois V
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(13):e2011269118
Estrogen receptor β and treatment with a phytoestrogen are associated with inhibition of nuclear translocation of EGFR in the prostate
Wu W-F; Wang L; Spetsieris N; Boukovala M; Efstathiou E; Brossner C; Warner M; Gustafsson J-A
Article: MUCOSAL IMMUNOLOGY. 2021;14(2):411-419
Liver X receptor regulates Th17 and RORγt⁺Treg cells by distinct mechanisms
Parigi SM; Das S; Frede A; Cardoso RF; Tripathi KP; Donas C; Hu YOO; Antonson P; Engstrand L; Gustafsson J-A; Villablanca EJ
Article: CHEMOSPHERE. 2021;265:129051
Bisphenol-S and Bisphenol-F alter mouse pancreatic β-cell ion channel expression and activity and insulin release through an estrogen receptor ERβ mediated pathway
Marroqui L; Martinez-Pinna J; Castellano-Munoz M; dos Santos RS; Medina-Gali RM; Soriano S; Quesada I; Gustafsson J-A; Encinar JA; Nadal A
Article: THERANOSTICS. 2021;11(12):6074-6089
Female mice lacking ERβ display excitatory/inhibitory synaptic imbalance to drive the pathogenesis of temporal lobe epilepsy
Wang Z; Xie R; Yang X; Yin H; Li X; Liu T; Ma Y; Gao J; Zang Z; Ruan R; Li Y; Huang K; Chen Q; Shen K; Lv S; Zhang C; Yang H; Warner M; Gustafsson J-A; Liu S; Fan X
Article: FRONTIERS IN ENDOCRINOLOGY. 2021;12:721813
Expression of Sex Hormone Receptor and Immune Response Genes in Peripheral Blood Mononuclear Cells During the Menstrual Cycle
Brundin PMA; Landgren B-M; Fjallstrom P; Shamekh MMM; Gustafsson J-A; Johansson AFF; Nalvarte I
Article: NEUROENDOCRINOLOGY. 2021;111(1-2):27-44
Motor Function Deficits in the Estrogen Receptor Beta Knockout Mouse: Role on Excitatory Neurotransmission and Myelination in the Motor Cortex
Varshney MK; Yu NY-L; Katayama S; Li X; Liu T; Wu W-F; Tohonen V; Krjutskov K; Kere J; Fan X; Inzunza J; Gustafsson J-A; Nalvarte I
Article: CANCER LETTERS. 2020;492:54-62
Intestinal estrogen receptor beta suppresses colon inflammation and tumorigenesis in both sexes
Hases L; Indukuri R; Birgersson M; Trang N-V; Lozano R; Saxena A; Hartman J; Frasor J; Gustafsson J-A; Katajisto P; Archer A; Williams C
Article: FOOD AND CHEMICAL TOXICOLOGY. 2020;145:111681
Bisphenol-A exposure during pregnancy alters pancreatic β-cell division and mass in male mice offspring: A role for ERβ
Boronat-Belda T; Ferrero H; Al-Abdulla R; Quesada I; Gustafsson J-A; Nadal A; Alonso-Magdalena P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(42):26347-26355
Estrogen receptor β regulates AKT activity through up-regulation of INPP4B and inhibits migration of prostate cancer cell line PC-3
Chaurasiya S; Wu W; Strom AM; Warner M; Gustafsson J-A
Article: ISCIENCE. 2020;23(9):101458
Pharmacological Activation of Estrogen Receptor Beta Overcomes Tumor Resistance to Immune Checkpoint Blockade Therapy
Huang S; Zhou N; Zhao L; Gimple RC; Ahn YH; Zhang P; Wang W; Shao B; Yang J; Zhang Q; Zhao S; Jiang X; Chen Z; Zeng Y; Hu H; Gustafsson J-A; Zhou S
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2020;24(17):9925-9935
The absence of oestrogen receptor beta disturbs collagen I type deposition during Achilles tendon healing by regulating the IRF5-CCL3 axis
Bian X; Liu T; Yang M; Gu C; He G; Zhou M; Tang H; Lu K; Lai F; Wang F; Yang Q; Gustafsson J-A; Fan X; Tang K
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2020;529(2):231-237
Generation of an all-exon Esr2 deleted mouse line: Effects on fertility
Antonson P; Apolinario LM; Shamekh MM; Humire P; Poutanen M; Ohlsson C; Nalvarte I; Gustafsson J-A
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2020;217(5):e20191660
Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain
Bogie JFJ; Grajchen E; Wouters E; Corrales AG; Dierckx T; Vanherle S; Mailleux J; Gervois P; Wolfs E; Dehairs J; Van Broeckhoven J; Bowman AP; Lambrichts I; Gustafsson J-A; Remaley AT; Mulder M; Swinnen JV; Haidar M; Ellis SR; Ntambi JM; Zelcer N; Hendriks JJA
Article: THE FASEB JOURNAL. 2020;34(5):7118-7126
Estrogen receptor alpha signaling in extrahypothalamic neurons during late puberty decreases bone size and strength in female but not in male mice.
Kim NR; Jardí F; Khalil R; Antonio L; Schollaert D; Deboel L; van Lenthe GH; Decallonne B; Carmeliet G; Gustafsson J-Å; Claessens F; Ohlsson C; Lagerquist MK; Dubois V; Vanderschueren D
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2020;318(5):E646-E654
The effects of estradiol are modulated in a tissue-specific manner in mice with inducible inactivation of ERα after sexual maturation
Ohlsson C; Farman HH; Gustafsson KL; Wu J; Henning P; Windahl SH; Sjogren K; Gustafsson J-A; Moverare-Skrtic S; Lagerquist MK
Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2020;198:105558
Lipidomic analysis of human primary hepatocytes following LXR activation with GW3965 identifies AGXT2L1 as a main target associated to changes in phosphatidylethanolamine
Santinha D; Klopot A; Marques I; Ellis E; Jorns C; Johansson H; Melo T; Antonson P; Jakobsson T; Felix V; Gustafsson J-A; Domingues MR; Mode A; Helguero LA
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(9):4902-4909
Ventral prostate and mammary gland phenotype in mice with complete deletion of the ERβ gene
Warner M; Wu W-F; Montanholi L; Nalvarte I; Antonson P; Gustafsson J-A
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2020;502:110672
Selective estrogen receptor (ER)β activation provokes a redistribution of fat mass and modifies hepatic triglyceride composition in obese male mice
Gonzalez-Granillo M; Savva C; Li X; Laskar MG; Angelin B; Gustafsson J-A; Korach-Andre M
Article: JOURNAL OF VISUALIZED EXPERIMENTS. 2020;(155)
A Layered Mounting Method for Extended Time-Lapse Confocal Microscopy of Whole Zebrafish Embryos
Upadhyay S; Vergara L; Shah P; Gustafsson J-A; Kakadiaris IA; Bondesson M
Article: PLOS ONE. 2020;15(5):e0226057
Estrogen receptor β exerts tumor suppressive effects in prostate cancer through repression of androgen receptor activity
Chaurasiya S; Widmann S; Botero C; Lin C-Y; Gustafsson J-A; Strom AM
Article: MOLECULAR THERAPY: METHODS & CLINICAL DEVELOPMENT. 2019;15:359-370
mRNA as a Novel Treatment Strategy for Hereditary Spastic Paraplegia Type 5
Hauser S; Poenisch M; Schelling Y; Hoeflinger P; Schuster S; Teegler A; Betten R; Gustafsson J-A; Huebener-Schmid J; Schlake T; Chevessier-Tuennesen F; Horscroft N; Bjorkhem I; Schoels L
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2019;23(11):7406-7416
Absence of estrogen receptor beta leads to abnormal adipogenesis during early tendon healing by an up-regulation of PPARγ signalling
Bian X; Liu T; Zhou M; He G; Ma Y; Shi Y; Wang Y; Tang H; Kang X; Yang M; Gustafsson J-A; Fan X; Tang K
Article: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2019;380:114709
Differential activity of BPA, BPAF and BPC on zebrafish estrogen receptors in vitro and in vivo
Pinto C; Hao R; Grimaldi M; Thrikawala S; Boulahtouf A; Ait-Aissa S; Brion F; Gustafsson J-A; Balaguer P; Bondesson M
Article: DIABETOLOGIA. 2019;62(9):1667-1680
Oestrogen receptor β mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells
Martinez-Pinna J; Marroqui L; Hmadcha A; Lopez-Beas J; Soriano S; Villar-Pazos S; Alonso-Magdalena P; Dos Santos RS; Quesada I; Martin F; Soria B; Gustafsson J-A; Nadal A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(33):16507-16512
Retinal and optic nerve degeneration in liver X receptor β knockout mice
Song X-Y; Wu W-F; Gabbi C; Dai Y-B; So M; Chaurasiya SP; Wang L; Warner M; Gustafsson J-A
Article: SCIENTIFIC REPORTS. 2019;9(1):10306
Bisphenol A Regulates Sodium Ramp Currents in Mouse Dorsal Root Ganglion Neurons and Increases Nociception
Soriano S; Gil-Rivera M; Marroqui L; Alonso-Magdalena P; Fuentes E; Gustafsson J-A; Nadal A; Martinez-Pinna J
Article: INTERNATIONAL JOURNAL OF CANCER. 2019;144(12):3086-3098
Colitis-induced colorectal cancer and intestinal epithelial estrogen receptor beta impact gut microbiota diversity
Ibrahim A; Hugerth LW; Hases L; Saxena A; Seifert M; Thomas Q; Gustafsson J-A; Engstrand L; Williams C
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(17):8457-8462
VSMC-specific EP4 deletion exacerbates angiotensin II-induced aortic dissection by increasing vascular inflammation and blood pressure
Xu H; Du S; Fang B; Li C; Jia X; Zheng S; Wang S; Li Q; Su W; Wang N; Zheng F; Chen L; Zhang X; Gustafsson J-A; Guan Y
Article: BIOLOGY OF SEX DIFFERENCES. 2019;10(1):11
Sex-specific lipid molecular signatures in obesity-associated metabolic dysfunctions revealed by lipidomic characterization in ob/ob mouse
Gonzalez-Granillo M; Helguero LA; Alves E; Archer A; Savva C; Pedrelli M; Ahmed O; Li X; Domingues MR; Parini P; Gustafsson J-A; Korach-Andre M
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2019;479:147-158
ERβ activation in obesity improves whole body metabolism via adipose tissue function and enhanced mitochondria biogenesis
Gonzalez-Granillo M; Savva C; Li X; Fitch M; Pedrelli M; Hellerstein M; Parini P; Korach-Andre M; Gustafsson J-A
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1811
Liver X Receptor Alpha Is Important in Maintaining Blood-Brain Barrier Function
Wouters E; de Wit NM; Vanmol J; van der Pol SMA; Hof BVH; Sommer D; Loix M; Geerts D; Gustafsson JA; Steffensen KR; Vanmierlo T; Bogie JFJ; Hendriks JJA; de Vries HE
Article: CELL REPORTS. 2018;25(13):3774-3785.e4
LXR Suppresses Inflammatory Gene Expression and Neutrophil Migration through cis-Repression and Cholesterol Efflux
Thomas DG; Doran AC; Fotakis P; Westerterp M; Antonson P; Jiang H; Jiang X-C; Gustafsson J-A; Tabas I; Tall AR
Article: NATURE COMMUNICATIONS. 2018;9(1):5457
Molecular and functional heterogeneity of IL-10-producing CD4⁺ T cells
Brockmann L; Soukou S; Steglich B; Czarnewski P; Zhao L; Wende S; Bedke T; Ergen C; Manthey C; Agalioti T; Geffken M; Seiz O; Parigi SM; Sorini C; Geginat J; Fujio K; Jacobs T; Roesch T; Izbicki JR; Lohse AW; Flavell RA; Krebs C; Gustafsson J-A; Antonson P; Roncarolo MG; Villablanca EJ; Gagliani N; Huber S
Article: ONCOTARGET. 2018;9(91):36273-36288
The estrogen receptor variants β2 and β5 induce stem cell characteristics and chemotherapy resistance in prostate cancer through activation of hypoxic signaling.
Faria M; Shepherd P; Pan Y; Chatterjee SS; Navone N; Gustafsson J-Å; Strom A
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2018;471:33-41
Genomics of sex hormone receptor signaling in hepatic sexual dimorphism
Zheng D; Wang X; Antonson P; Gustafsson J-A; Li Z
Article: JOURNAL OF ENDOCRINOLOGY. 2018;238(2):129-136
ERα expression in T lymphocytes is dispensable for estrogenic effects in bone
Gustafsson KL; Nilsson KH; Farman HH; Andersson A; Lionikaite V; Henning P; Wu J; Windahl SH; Islander U; Moverare-Skrtic S; Sjogren K; Carlsten H; Gustafsson J-A; Ohlsson C; Lagerquist MK
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2018;115(21):5600-5605
Farnesoid X receptor is essential for the survival of renal medullary collecting duct cells under hypertonic stress
Xu S; Huang S; Luan Z; Chen T; Wei Y; Xing M; Li Y; Du C; Wang B; Zheng F; Wang N; Guan Y; Gustafsson J-A; Zhang X
Article: ONCOTARGET. 2018;9(32):22509-22522
ERβ alters the chemosensitivity of luminal breast cancer cells by regulating p53 function.
Bado I; Pham E; Soibam B; Nikolos F; Gustafsson J-Å; Thomas C
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2018;115(16):E3673-E3681
Pharmacological activation of estrogen receptor beta augments innate immunity to suppress cancer metastasis
Zhao L; Huang S; Mei S; Yang Z; Xu L; Zhou N; Yang Q; Shen Q; Wang W; Le X; Lau WB; Lau B; Wang X; Yi T; Zhao X; Wei Y; Warner M; Gustafsson J-A; Zhou S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2018;115(12):E2725-E2733
Liver X receptor β regulates the development of the dentate gyrus and autistic-like behavior in the mouse
Cai Y; Tang X; Chen X; Li X; Wang Y; Bao X; Wang L; Sun D; Zhao J; Xing Y; Warner M; Xu H; Gustafsson J-A; Fan X
Article: ONCOTARGET. 2018;9(15):12201-12211
The ERβ4 variant induces transformation of the normal breast mammary epithelial cell line MCF-10A; the ERβ variants ERβ2 and ERβ5 increase aggressiveness of TNBC by regulation of hypoxic signaling.
Faria M; Karami S; Granados-Principal S; Dey P; Verma A; Choi DS; Elemento O; Bawa-Khalfe T; Chang JC; Strom AM; Gustafsson J-Å
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2018;115(2):427-432
Body weight homeostat that regulates fat mass independently of leptin in rats and mice
Jansson J-O; Palsdottir V; Hagg DA; Schele E; Dickson SL; Anesten F; Bake T; Montelius M; Bellman J; Johansson ME; Cone RD; Drucker DJ; Wu J; Aleksic B; Tornqvist AE; Sjogren K; Gustafsson J-A; Windahl SH; Ohlsson C
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(48):E10428-E10437
Role of estrogen receptor beta in neural differentiation of mouse embryonic stem cells
Varshney MK; Inzunza J; Lupu D; Ganapathy V; Antonson P; Ruegg J; Nalvarte I; Gustafsson J-A
Article: ONCOTARGET. 2017;8(44):76622-76633
Estrogen receptor β2 induces proliferation and invasiveness of triple negative breast cancer cells; association with regulation of PHD3 and HIF-1α
Bialesova L; Xu L; Gustafsson J-A; Haldosen L-A; Zhao C; Dahlman-Wright K
Article: SCIENTIFIC REPORTS. 2017;7(1):11770
Molecular mechanisms involved in the non-monotonic effect of bisphenol-a on ca2+entry in mouse pancreatic β-cells
Villar-Pazos S; Martinez-Pinna J; Castellano-Munoz M; Alonso-Magdalena P; Marroqui L; Quesada I; Gustafsson J-A; Nadal A
Article: REPRODUCTIVE TOXICOLOGY. 2017;70:60-69
Identification of vascular disruptor compounds by analysis in zebrafish embryos and mouse embryonic endothelial cells
McCollum CW; Conde-Vancells J; Hans C; Vazquez-Chantada M; Kleinstreuer N; Tal T; Knudsen T; Shah SS; Merchant FA; Finnell RH; Gustafsson J-A; Cabrera R; Bondesson M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(19):E3816-E3822
Estrogen receptor β, a regulator of androgen receptor signaling in the mouse ventral prostate
Wu W-F; Maneix L; Insunza J; Nalvarte I; Antonson P; Kere J; Yu NY-L; Tohonen V; Katayama S; Einarsdottir E; Krjutskov K; Dai Y-B; Huang B; Su W; Warner M; Gustafsson J-A
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2017;312(4):E357-E367
Liver X receptor α induces 17 β-hydroxysteroid dehydrogenase-13 expression through SREBP-1c
Su W; Peng J; Li S; Dai Y-B; Wang C-J; Xu H; Gao M; Ruan X-Z; Gustafsson J-A; Guan Y-F; Zhang X-Y
Article: AMERICAN JOURNAL OF PHYSIOLOGY - RENAL PHYSIOLOGY. 2017;312(4):F619-F628
Liver X receptor β increases aquaporin 2 protein level via a posttranscriptional mechanism in renal collecting ducts
Su W; Huang S-Z; Gao M; Kong X-M; Gustafsson J-A; Xu S-J; Wang B; Zheng F; Chen L-H; Wang N-P; Guan Y-F; Zhang X-Y
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(12):3181-3185
Ablation of cytochrome P450 omega-hydroxylase 4A14 gene attenuates hepatic steatosis and fibrosis
Zhang X; Li S; Zhou Y; Su W; Ruan X; Wang B; Zheng F; Warner M; Gustafsson J-A; Guan Y
Article: MOLECULAR NEUROBIOLOGY. 2017;54(2):1467-1481
Liver X Receptor β Is Involved in Formalin-Induced Spontaneous Pain
Bao X; Cai Y; Wang Y; Zhao J; He X; Yu D; Huang J; Jing S; Du Z; Yang T; Warner M; Gustafsson J-A; Fan X
Article: WORLD JOURNAL OF GASTROENTEROLOGY. 2017;23(3):426-436
Sex differences and effects of oestrogen in rat gastric mucosal defence
Shore R; Bjorne H; Omoto Y; Siemiatkowska A; Gustafsson J-A; Lindblad M; Holm L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(3):592-597
Speedy A-Cdk2 binding mediates initial telomere-nuclear envelope attachment during meiotic prophase I independent of Cdk2 activation
Tu Z; Bayazit MB; Liu H; Zhang J; Busayavalasa K; Risal S; Shao J; Satyanarayana A; Coppola V; Tessarollo L; Singh M; Zheng C; Han C; Chen Z; Kaldis P; Gustafsson J-A; Liu K
Article: SCIENTIFIC REPORTS. 2016;6:38579
An ERβ agonist induces browning of subcutaneous abdominal fat pad in obese female mice
Miao Y-F; Su W; Dai Y-B; Wu W-F; Huang B; Barros RPA; Nguyen H; Maneix L; Guan Y-F; Warner M; Gustafsson J-A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2016;113(42):11883-11888
Dysregulation of Notch and ERα signaling in AhR^-/- male mice
Huang B; Butler R; Miao Y; Dai Y; Wu W; Su W; Fujii-Kuriyama Y; Warner M; Gustafsson J-A
Article: IMMUNITY, INFLAMMATION AND DISEASE. 2016;4(3):350-361
Cholesterol-sensing liver X receptors stimulate Th2-driven allergic eosinophilic asthma in mice.
Smet M; Van Hoecke L; De Beuckelaer A; Vander Beken S; Naessens T; Vergote K; Willart M; Lambrecht BN; Gustafsson J-Å; Steffensen KR; Grooten J
Article: ONCOTARGET. 2016;7(35):56170-56182
Memo interacts with c-Src to control Estrogen Receptor alpha sub-cellular localization
Frei A; MacDonald G; Lund I; Gustafsson J-A; Hynes NE; Nalvarte I
Article: SCIENTIFIC REPORTS. 2016;6:29473
The role of membrane ERα signaling in bone and other major estrogen responsive tissues.
Gustafsson KL; Farman H; Henning P; Lionikaite V; Movérare-Skrtic S; Wu J; Ryberg H; Koskela A; Gustafsson J-Å; Tuukkanen J; Levin ER; Ohlsson C; Lagerquist MK
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2016;113(27):7614-7619
Ablation of Liver X receptors α and β leads to spontaneous peripheral squamous cell lung cancer in mice.
Dai Y-B; Miao Y-F; Wu W-F; Li Y; D'Errico F; Su W; Burns AR; Huang B; Maneix L; Warner M; Gustafsson J-Å
Article: ONCOTARGET. 2016;7(27):42159-42171
Estrogen receptor beta reduces colon cancer metastasis through a novel miR-205-PROX1 mechanism
Trang N-V; Wang J; Mesmar F; Mukhopadhyay S; Saxena A; McCollum CW; Gustafsson J-A; Bondesson M; Williams C
Article: MOLECULAR PSYCHIATRY. 2016;21(6):844-856
Liver X receptors regulate cerebrospinal fluid production
Dai Y-B; Wu W-F; Huang B; Miao Y-F; Nadarshina S; Warner M; Gustafsson J-A
Article: SCIENCE TRANSLATIONAL MEDICINE. 2016;8(333):333ra50
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming
Zimmer S; Grebe A; Bakke SS; Bode N; Halvorsen B; Ulas T; Skjelland M; De Nardo D; Labzin LI; Kerksiek A; Hempel C; Heneka MT; Hawxhurst V; Fitzgerald ML; Trebicka J; Bjorkhem I; Gustafsson J-A; Westerterp M; Tall AR; Wright SD; Espevik T; Schultze JL; Nickenig G; Lutjohann D; Latz E
Article: ADIPOCYTE. 2016;5(2):238-242
Liver X receptor β: new player in the regulatory network of thyroid hormone and 'browning' of white fat
Miao Y; Warner M; Gustafsson J-A
Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2016;157:3-6
Historical overview of nuclear receptors
Gustafsson J-A
Article: REPRODUCTION. 2016;151(3):253-259
Estrogen rleceptor β controls MMP-19 expression in mouse ovaries during ovulation
Nalvarte I; Tohonen V; Lindeberg M; Varshney M; Gustafsson J-A; Inzunza J
Article: LABORATORY INVESTIGATION. 2016;96(2):230-238
Nuclear hormone receptor LXRα inhibits adipocyte differentiation of mesenchymal stem cells with Wnt/beta-catenin signaling
Matsushita K; Morello F; Zhang Z; Masuda T; Iwanaga S; Steffensen KR; Gustafsson J-A; Pratt RE; Dzau VJ
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2016;419(C):29-43
Lxr regulates lipid metabolic and visual perception pathways during zebrafish development
Pinto CL; Kalasekar SM; McCollum CW; Riu A; Jonsson P; Lopez J; Swindell EC; Bouhlatouf A; Balaguer P; Bondesson M; Gustafsson J-A
Article: METHODS IN MOLECULAR BIOLOGY. 2016;1366:425-430
Estrogen Receptor-α Knockout Mice.
Antonson P; Humire P; Gustafsson J-Å
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(48):14972-14977
The bone-sparing effects of estrogen and WNT16 are independent of each other
Moverare-Skrtic S; Wu J; Henning P; Gustafsson KL; Sjogren K; Windahl SH; Koskela A; Tuukkanen J; Borjesson AE; Lagerquist MK; Lerner UH; Zhang F-P; Gustafsson J-A; Poutanen M; Ohlsson C
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(45):14006-14011
Liver X receptor β controls thyroid hormone feedback in the brain and regulates browning of subcutaneous white adipose tissue
Miao Y; Wu W; Dai Y; Maneix L; Huang B; Warner M; Gustafsson J-A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2015;466(4):650-655
Identification of proteins highly expressed in uterine fluid from mice with hydrometra
Antonson P; Nalvarte I; Varshney M; Xu L; Windahl SH; Humire P; Ohlsson C; Gustafsson J-A; Dahlman-Wright K
Article: EMBO MOLECULAR MEDICINE. 2015;7(9):1229-1243
Cardiac LXR protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization
Cannon MV; Sillje HHW; Sijbesma JWA; Vreeswijk-Baudoin I; Ciapaite J; van der Sluis B; van Deursen J; Silva GJJ; de Windt LJ; Gustafsson J-A; van der Harst P; van Gilst WH; de Boer RA
Article: REPRODUCTIVE TOXICOLOGY. 2015;55:3-10
Comparison of toxicity values across zebrafish early life stages and mammalian studies: Implications for chemical testing
Ducharme NA; Reif DM; Gustafsson J-A; Bondesson M
Article: REPRODUCTIVE TOXICOLOGY. 2015;55:20-29
Identification of environmental chemicals that induce yolk malabsorption in zebrafish using automated image segmentation
Kalasekar SM; Zacharia E; Kessler N; Ducharme NA; Gustafsson J-A; Kakadiaris IA; Bondesson M
Article: BEST PRACTICE AND RESEARCH: CLINICAL ENDOCRINOLOGY AND METABOLISM. 2015;29(4):557-568
Estrogen receptor alpha and beta in health and disease
Jia M; Dahlman-Wright K; Gustafsson J-A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(16):5135-5140
Estrogen receptor β exon 3-deleted mouse: The importance of non-ERE pathways in ERβ signaling
Maneix L; Antonson P; Humire P; Rochel-Maia S; Castaneda J; Omoto Y; Kim H-J; Warner M; Gustafsson J-A
Article: PLOS ONE. 2015;10(5):e0128239
Estrogen Receptor β2 Induces Hypoxia Signature of Gene Expression by Stabilizing HIF-1α in Prostate Cancer
Dey P; Velazquez-Villegas LA; Faria M; Turner A; Jonsson P; Webb P; Williams C; Gustafsson J-A; Stroem AM
Article: DIABETES. 2015;64(1):60-71
PRMT3 Regulates Hepatic Lipogenesis Through Direct Interaction With LXRα
Kim D-I; Park M-J; Lim S-K; Park J-I; Yoon K-C; Han H-J; Gustafsson J-A; Lim J-H; Park S-H
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(50):17983-17988
Life-long in vivo cell-lineage tracing shows that no oogenesis originates from putative germline stem cells in adult mice
Zhang H; Liu L; Li X; Busayavalasa K; Shen Y; Hovatta O; Gustafsson J-A; Liu K
Article: JOURNAL OF PROTEOME RESEARCH. 2014;13(12):5829-5836
Comparative Proteomic Analysis Reveals Sex and Estrogen Receptor β Effects in the Pressure Overloaded Heart
Kararigas G; Fliegner D; Forler S; Klein O; Schubert C; Gustafsson J-A; Klose J; Regitz-Zagrosek V
Article: JOURNAL OF CLINICAL INVESTIGATION. 2014;124(11):4829-4842
Cholestenoic acids regulate motor neuron survival via liver X receptors
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Article: MUCOSAL IMMUNOLOGY. 2014;7(6):1416-1428
The oxysterol receptor LXRβ protects against DSS- and TNBS-induced colitis in mice
Jakobsson T; Vedin L-L; Hassan T; Venteclef N; Greco D; D'Amato M; Treuter E; Gustafsson J-A; Steffensen KR
Article: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2014;280(1):60-69
Selectivity of natural, synthetic and environmental estrogens for zebrafish estrogen receptors
Pinto C; Grimaldi M; Boulahtouf A; Pakdel F; Brion F; Ait-Aissa S; Cavailles V; Bourguet W; Gustafsson J-A; Bondesson M; Balaguer P
Article: ONCOGENE. 2014;33(33):4213-4225
Estrogen receptor β upregulates FOXO3a and causes induction of apoptosis through PUMA in prostate cancer
Dey P; Stroem A; Gustafsson J-A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(31):11443-11448
Transcriptional regulation of the sodium-coupled neutral amino acid transporter (SNAT2) by 17β-estradiol
Velazquez-Villegas LA; Ortiz V; Stroem A; Torres N; Engler DA; Matsunami R; Ordaz-Rosado D; Garcia-Becerra R; Lopez-Barradas AM; Larrea F; Gustafsson J-A; Tovar AR
Article: MOLECULAR PSYCHIATRY. 2014;19(8):947-957
Liver X receptor β is essential for the differentiation of radial glial cells to oligodendrocytes in the dorsal cortex
Xu P; Xu H; Tang X; Xu L; Wang Y; Guo L; Yang Z; Xing Y; Wu Y; Warner M; Gustafsson J-A; Fan X
Article: NEUROCHEMISTRY INTERNATIONAL. 2014;71:8-16
Liver X receptor β delays transformation of radial glial cells into astrocytes during mouse cerebral cortical development
Guo L; Xu P; Tang X; Wu Q; Xing Y; Gustafsson J-A; Xu H; Fan X
Article: TOXICOLOGICAL SCIENCES. 2014;139(1):48-58
Halogenated Bisphenol-A Analogs Act as Obesogens in Zebrafish Larvae (Danio rerio)
Riu A; McCollum CW; Pinto CL; Grimaldi M; Hillenweck A; Perdu E; Zalko D; Bernard L; Laudet V; Balaguer P; Bondesson M; Gustafsson J-A
Article: HEPATOLOGY. 2014;59(5):1791-1802
Estrogen Receptor Ligands Ameliorate Fatty Liver Through a Nonclassical Estrogen Receptor/Liver X Receptor Pathway in Mice
Han S-I; Komatsu Y; Murayama A; Steffensen KR; Nakagawa Y; Nakajima Y; Suzuki M; Oie S; Parini P; Vedin L-L; Kishimoto H; Shimano H; Gustafsson J-A; Yanagisawa J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2014;446(3):647-650
Action mechanisms of Liver X Receptors
Gabbi C; Warner M; Gustafsson J-A
Article: NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2014;21(3):277-281
Structure of the retinoid X receptor α-liver X receptor β (RXRα-LXRβ) heterodimer on DNA
Lou X; Toresson G; Benod C; Suh JH; Philips KJ; Webb P; Gustafsson J-A
Article: TOXICOLOGICAL SCIENCES. 2014;138(1):21-35
Coexposure to Phytoestrogens and Bisphenol A Mimics Estrogenic Effects in an Additive Manner
Katchy A; Pinto C; Jonsson P; Trang N-V; Pandelova M; Riu A; Schramm K-W; Samarov D; Gustafsson J-A; Bondesson M; Williams C
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2014;306(5):E494-E502
Skeletal muscle as a target of LXR agonist after long-term treatment: focus on lipid homeostasis
Archer A; Laurencikiene J; Ahmed O; Steffensen KR; Parini P; Gustafsson J-A; Korach-Andre M
Article: BREAST CANCER RESEARCH. 2014;16(1):R21
Estrogen receptor beta as a novel target of androgen receptor action in breast cancer cell lines
Rizza P; Barone I; Zito D; Giordano F; Lanzino M; De Amicis F; Mauro L; Sisci D; Catalano S; Wright KD; Gustafsson J-A; Ando S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(6):2277-2282
Farnesoid X receptor (FXR) gene deficiency impairs urine concentration in mice
Zhang X; Huang S; Gao M; Liu J; Jia X; Han Q; Zheng S; Miao Y; Li S; Weng H; Xia X; Du S; Wu W; Gustafsson J-A; Guan Y
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(5):1933-1938
Differential expression of estrogen receptor α, β1, and β2 in lobular and ductal breast cancer
Huang B; Omoto Y; Iwase H; Yamashita H; Toyama T; Coombes RC; Filipovic A; Warner M; Gustafsson J-A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(3):1180-1185
The estrogen receptor antagonist ICI 182,780 can act both as an agonist and an inverse agonist when estrogen receptor α AF-2 is modified
Moverare-Skrtic S; Borjesson AE; Farman HH; Sjogren K; Windahl SH; Lagerquist MK; Andersson A; Stubelius A; Carlsten H; Gustafsson J-A; Ohlsson C
Article: PLOS ONE. 2014;9(9):e106289
Antiproliferative Effects and Mechanisms of Liver X Receptor Ligands in Pancreatic Ductal Adenocarcinoma Cells
Candelaria NR; Addanki S; Zheng J; Trang N-V; Karaboga H; Dey P; Gabbi C; Vedin L-L; Liu K; Wu W; Jonsson PK; Lin JZ; Su F; Bollu LR; Hodges SE; McElhany AL; Issazadeh MA; Fisher WE; Ittmann MM; Steffensen KR; Gustafsson J-A; Lin C-Y
Article: PLOS ONE. 2014;9(4):e93552
Hepatic ACAT2 Knock Down Increases ABCA1 and Modifies HDL Metabolism in Mice
Pedrelli M; Davoodpour P; Degirolamo C; Gomaraschi M; Graham M; Ossoli A; Larsson L; Calabresi L; Gustafsson J-A; Steffensen KR; Eriksson M; Parini P
Article: PLOS ONE. 2014;9(1):e85581
aP2-Cre-Mediated Inactivation of Estrogen Receptor Alpha Causes Hydrometra
Antonson P; Matic M; Portwood N; Kuiper RV; Bryzgalova G; Gao H; Windahl SH; Humire P; Ohlsson C; Berggren P-O; Gustafsson J-A; Dahlman-Wright K
Article: MOLECULAR CARCINOGENESIS. 2013;52(11):835-844
The oxysterol receptors LXRα and LXRβ suppress proliferation in the colon.
Vedin L-L; Gustafsson J-Å; Steffensen KR
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2013;210(9):1711-1728
The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils
Raccosta L; Fontana R; Maggioni D; Lanterna C; Villablanca EJ; Paniccia A; Musumeci A; Chiricozzi E; Trincavelli ML; Daniele S; Martini C; Gustafsson J-A; Doglioni C; Feo SG; Leiva A; Ciampa MG; Mauri L; Sensi C; Prinetti A; Eberini I; Mora JR; Bordignon C; Steffensen KR; Sonnino S; Sozzani S; Traversari C; Russo V
Article: HEPATOLOGY. 2013;58(2):617-628
Thyroid hormone-responsive SPOT 14 homolog promotes hepatic lipogenesis, and its expression is regulated by Liver X receptor through a sterol regulatory element-binding protein 1c-dependent mechanism in mice
Wu J; Wang C; Li S; Li S; Wang W; Li J; Chi Y; Yang H; Kong X; Zhou Y; Dong C; Wang F; Xu G; Yang J; Gustafsson J-A; Guan Y
Article: CARCINOGENESIS. 2013;34(7):1431-1441
Estrogen receptor expression induces changes in the microRNA pool in human colon cancer cells
Edvardsson K; Trang N-V; Kalasekar SM; Ponten F; Gustafsson J-A; Williams C
Article: BREAST CANCER RESEARCH. 2013;15(3):R51
Liver x receptor ligands disrupt breast cancer cell proliferation through an E2F-mediated mechanism
Trang N-V; Vedin L-L; Liu K; Jonsson P; Lin JZ; Candelaria NR; Candelaria LP; Addanki S; Williams C; Gustafsson J-A; Steffensen KR; Lin C-Y
Article: DIABETES. 2013;62(6):2015-2025
Antidiabetic Actions of an Estrogen Receptor β Selective Agonist
Alonso-Magdalena P; Ropero AB; Garcia-Arevalo M; Soriano S; Quesada I; Muhammed SJ; Salehi A; Gustafsson J-A; Nadal A
Article: MOLECULAR PSYCHIATRY. 2013;18(6):674-680
Involvement of estrogen receptor β in maintenance of serotonergic neurons of the dorsal raphe
Suzuki H; Barros RPA; Sugiyama N; Krishnan V; Yaden BC; Kim H-J; Warner M; Gustafsson J-A
Article: ONCOGENE. 2013;32(19):2390-2402
Estrogen receptor beta growth-inhibitory effects are repressed through activation of MAPK and PI3K signalling in mammary epithelial and breast cancer cells
Cotrim CZ; Fabris V; Doria ML; Lindberg K; Gustafsson J-A; Amado F; Lanari C; Helguero LA
Article: JOURNAL OF LIPID RESEARCH. 2013;54(5):1300-1311
LXR activation by GW3965 alters fat tissue distribution and adipose tissue inflammation in ob/ob female mice
Archer A; Stolarczyk E; Doria ML; Helguero L; Domingues R; Howard JK; Mode A; Korach-Andre M; Gustafsson J-A
Article: MENOPAUSE. 2013;20(5):496-503
Effects of short-term estradiol and norethindrone acetate treatment on the breasts of normal postmenopausal women
Cheng G; Butler R; Warner M; Gustafsson J-A; Wilczek B; Landgren B-M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(9):3543-3548
Targeting estrogen receptor β in microglia and T cells to treat experimental autoimmune encephalomyelitis.
Wu W-F; Tan X-J; Dai Y-B; Krishnan V; Warner M; Gustafsson J-Å
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(6):2294-2299
Estrogen receptor-α in osteocytes is important for trabecular bone formation in male mice
Windahl SH; Borjesson AE; Farman HH; Engdahl C; Moverare-Skrtic S; Sjogren K; Lagerquist MK; Kindblom JM; Koskela A; Tuukkanen J; Pajevic PD; Feng JQ; Dahlman-Wright K; Antonson P; Gustafsson J-A; Ohlsson C
Article: NATURE CHEMICAL BIOLOGY. 2013;9(2):126-133
Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis
Theofilopoulos S; Wang Y; Kitambi SS; Sacchetti P; Sousa KM; Bodin K; Kirk J; Salto C; Gustafsson M; Toledo EM; Karu K; Gustafsson J-A; Steffensen KR; Ernfors P; Sjovall J; Griffiths WJ; Arenas E
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2013;430(1):375-380
The liver X receptor promotes macrophage differentiation and suppresses osteoclast formation in mouse RAW264.7 promyelocytic leukemia cells exposed to bacterial lipopolysaccharide
Remen KMR; Gustafsson J-A; Andersson G
Article: PLOS ONE. 2013;8(2):e57458
Estrogen Signalling and the Metabolic Syndrome: Targeting the Hepatic Estrogen Receptor Alpha Action
Matic M; Bryzgalova G; Gao H; Antonson P; Humire P; Omoto Y; Portwood N; Pramfalk C; Efendic S; Berggren P-O; Gustafsson J-A; Dahlman-Wright K
Article: BIOLOGY OF REPRODUCTION. 2013;88(1):7
Estrogen Receptors Alpha and Beta in Male and Female Gerbil Prostates
Rochel-Maia SS; Santos FCA; Alonso-Magdalena P; Goes RM; Vilamaior PSL; Warner M; Gustafsson J-A; Taboga SR
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2013;93(1):71-82
Activation of the liver X receptor-β potently inhibits osteoclastogenesis from lipopolysaccharide-exposed bone marrow-derived macrophages
Remen KMR; Lerner UH; Gustafsson J-A; Andersson G
Article: PLOS ONE. 2013;8(11):e79020
Identification of Estrogen Target Genes during Zebrafish Embryonic Development through Transcriptomic Analysis
Hao R; Bondesson M; Singh AV; Riu A; McCollum CW; Knudsen TB; Gorelick DA; Gustafsson J-A
Article: MOLECULAR ENDOCRINOLOGY. 2012;26(12):1980-1990
Fasting-Induced FGF21 Is Repressed by LXR Activation via Recruitment of an HDAC3 Corepressor Complex in Mice
Archer A; Venteclef N; Mode A; Pedrelli M; Gabbi C; Clement K; Parini P; Gustafsson J-A; Korach-Andre M
Article: MOLECULAR ENDOCRINOLOGY. 2012;26(12):1991-2003
Estrogen Receptors β1 and β2 Have Opposing Roles in Regulating Proliferation and Bone Metastasis Genes in the Prostate Cancer Cell Line PC3
Dey P; Jonsson P; Hartman J; Williams C; Stroem A; Gustafsson J-A
Article: HEPATOLOGY. 2012;56(6):2288-2296
Liver X Receptor β and Peroxisome Proliferator-Activated Receptor δ Regulate Cholesterol Transport in Murine Cholangiocytes
Xia X; Jung D; Webb P; Zhang A; Zhang B; Li L; Ayers SD; Gabbi C; Ueno Y; Gustafsson J-A; Alpini G; Moore DD; LeSage GD
Article: JOURNAL OF INTERNAL MEDICINE. 2012;272(5):452-464
LXRβ activation increases intestinal cholesterol absorption, leading to an atherogenic lipoprotein profile
Hu X; Steffensen KR; Jiang Z-Y; Parini P; Gustafsson J-A; Gafvels M; Eggertsen G
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2012;426(1):26-32
Global identification of genes regulated by estrogen signaling and demethylation in MCF-7 breast cancer cells
Putnik M; Zhao C; Gustafsson J-A; Dahlman-Wright K
Article: CARCINOGENESIS. 2012;33(9):1684-1691
Interplay between AP-1 and estrogen receptor in regulating gene expression and proliferation networks in breast cancer cells
Dahlman-Wright K; Qiao Y; Jonsson P; Gustafsson J-A; Williams C; Zhao C
Article: DIABETOLOGIA. 2012;55(9):2469-2478
Soy protein isoflavones differentially regulate liver X receptor isoforms to modulate lipid metabolism and cholesterol transport in the liver and intestine in mice
Gonzalez-Granillo M; Steffensen KR; Granados O; Torres N; Korach-Andre M; Ortiz V; Aguilar-Salinas C; Jakobsson T; Diaz-Villasenor A; Loza-Valdes A; Hernandez-Pando R; Gustafsson J-A; Tovar AR
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2012;424(4):710-716
Generation of ERα-floxed and knockout mice using the Cre/LoxP system
Antonson P; Omoto Y; Humire P; Gustafsson J-A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(32):13112-13117
Liver X receptor β protects dopaminergic neurons in a mouse model of Parkinson disease.
Dai Y-B; Tan X-J; Wu W-F; Warner M; Gustafsson J-Å
Article: BEHAVIOR GENETICS. 2012;42(4):509-527
The Aromatase Gene CYP19A1: Several Genetic and Functional Lines of Evidence Supporting a Role in Reading, Speech and Language
Anthoni H; Sucheston LE; Lewis BA; Tapia-Paez I; Fan X; Zucchelli M; Taipale M; Stein CM; Hokkanen M-E; Castren E; Pennington BF; Smith SD; Olson RK; Tomblin JB; Schulte-Koerne G; Noethen M; Schumacher J; Mueller-Myhsok B; Hoffmann P; Gilger JW; Hynd GW; Nopola-Hemmi J; Leppanen PHT; Lyytinen H; Schoumans J; Nordenskjold M; Spencer J; Stanic D; Boon WC; Simpson E; Makela S; Gustafsson J-A; Peyrard-Janvid M; Iyengar S; Kere J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(19):7493-7498
Anxiety in liver X receptor β knockout female mice with loss of glutamic acid decarboxylase in ventromedial prefrontal cortex.
Tan X-J; Dai Y-B; Wu W-F; Warner M; Gustafsson J-Å
Article: MOLECULAR ENDOCRINOLOGY. 2012;26(4):619-629
The rs3743205 SNP Is Important for the Regulation of the Dyslexia Candidate Gene DYX1C1 by Estrogen Receptor β and DNA Methylation
Tammimies K; Tapia-Paez I; Rueegg J; Rosin G; Kere J; Gustafsson J-A; Nalvarte I
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(8):3030-3034
Central diabetes insipidus associated with impaired renal aquaporin-1 expression in mice lacking liver X receptor β
Gabbi C; Kong X; Suzuki H; Kim H-J; Gao M; Jia X; Ohnishi H; Ueta Y; Warner M; Guan Y; Gustafsson J-A
Article: MOLECULAR AND CELLULAR BIOLOGY. 2012;32(4):852-867
Genome-Wide Profiling of Liver X Receptor, Retinoid X Receptor, and Peroxisome Proliferator-Activated Receptor α in Mouse Liver Reveals Extensive Sharing of Binding Sites
Boergesen M; Pedersen TA; Gross B; van Heeringen SJ; Hagenbeek D; Bindesboll C; Caron S; Lalloyer F; Steffensen KR; Nebb HI; Gustafsson J-A; Stunnenberg HG; Staels B; Mandrup S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(4):1122-1126
Uric acid stones in the urinary bladder of aryl hydrocarbon receptor (AhR) knockout mice
Butler R; Inzunza J; Suzuki H; Fujii-Kuriyama Y; Warner M; Gustafsson J-A
Article: PLOS ONE. 2012;7(2):e31109
Rapid insulinotropic action of low doses of bisphenol-A on mouse and human islets of Langerhans: role of estrogen receptor β.
Soriano S; Alonso-Magdalena P; García-Arévalo M; Novials A; Muhammed SJ; Salehi A; Gustafsson J-A; Quesada I; Nadal A
Article: PLOS ONE. 2012;7(3):e32080
Knockdown of SF-1 and RNF31 Affects Components of Steroidogenesis, TGFβ, and Wnt/β-catenin Signaling in Adrenocortical Carcinoma Cells
Ehrlund A; Jonsson P; Vedin L-L; Williams C; Gustafsson J-A; Treuter E
Article: PLOS ONE. 2012;7(9):e44998
Myelin-Derived Lipids Modulate Macrophage Activity by Liver X Receptor Activation
Bogie JFJ; Timmermans S; Van AH-T; Irrthum A; Smeets HJM; Gustafsson J-A; Steffensen KR; Mulder M; Stinissen P; Hellings N; Hendriks JJA
Article: LEUKEMIA AND LYMPHOMA. 2012;53(1):139-144
Up-regulated estrogen receptor β2 in chronic lymphocytic leukemia
Yakimchuk K; Norin S; Kimby E; Hagglund H; Warner M; Gustafsson J-A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(50):20090-20094
Estrogen receptor β and 17β-hydroxysteroid dehydrogenase type 6, a growth regulatory pathway that is lost in prostate cancer
Muthusamy S; Andersson S; Kim H-J; Butler R; Waage L; Bergerheim U; Gustafsson J-A
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2011;286(38):33084-33094
Activation of Liver X Receptor (LXR) Inhibits Receptor Activator of Nuclear Factor κB Ligand (RANKL)-induced Osteoclast Differentiation in an LXR β-dependent Mechanism
Remen KMR; Henning P; Lerner UH; Gustafsson J-A; Andersson G
Article: SURGICAL INFECTIONS. 2011;12(4):283-289
Liver X Receptor Protects against Liver Injury in Sepsis Caused by Rodent Cecal Ligation and Puncture
Wang YY; Ryg U; Dahle MK; Steffensen KR; Thiemermann C; Chaudry IH; Reinholt FP; Collins JL; Nebb HI; Aasen AO; Gustafsson J-A; Wang JE
Article: SCANDINAVIAN CARDIOVASCULAR JOURNAL. 2011;45(4):215-222
Estrogen receptors do not influence angiogenesis after myocardial infarction
Broberg AM; Siddiqui AJ; Fischer H; Grinnemo K-H; Wardell E; Andersson AB; Inzunza J; Sylven C; Gustafsson JA
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2011;96(8):E1237-E1245
In nonfunctional pituitary adenomas, estrogen receptors and slug contribute to development of invasiveness.
Zhou W; Song Y; Xu H; Zhou K; Zhang W; Chen J; Qin M; Yi H; Gustafsson J-A; Yang H; Fan X
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2011;301(1):E210-E222
Liver X receptors regulate de novo lipogenesis in a tissue-specific manner in C57BL/6 female mice
Korach-Andre M; Archer A; Gabbi C; Barros RP; Pedrelli M; Steffensen KR; Pettersson AT; Laurencikiene J; Parini P; Gustafsson J-A
Article: MOLECULAR ENDOCRINOLOGY. 2011;25(6):969-979
Estrogen Receptor β Induces Antiinflammatory and Antitumorigenic Networks in Colon Cancer Cells
Edvardsson K; Stroem A; Jonsson P; Gustafsson J-A; Williams C
Article: BREAST CANCER RESEARCH AND TREATMENT. 2011;127(2):417-427
Estrogen receptor beta decreases survival of p53-defective cancer cells after DNA damage by impairing G₂/M checkpoint signaling
Thomas CG; Strom A; Lindberg K; Gustafsson J-A
Article: AMERICAN JOURNAL OF PHYSIOLOGY - GASTROINTESTINAL AND LIVER PHYSIOLOGY. 2011;300(6):G1080-G1085
Amygdala activation by corticosterone alters visceral and somatic pain in cycling female rats.
Gustafsson JK; Greenwood-Van Meerveld B
Article: JOURNAL OF NEUROSCIENCE. 2011;31(19):7049-7059
Critical Role of Astroglial Apolipoprotein E and Liver X Receptor-α Expression for Microglial Aβ Phagocytosis
Terwel D; Steffensen KR; Verghese PB; Kummer MP; Gustafsson J-A; Holtzman DM; Heneka MT
Article: PHYSIOLOGICAL GENOMICS. 2011;43(8):438-446
Role of the estrogen/estrogen-receptor-beta axis in the genomic response to pressure overload-induced hypertrophy
Kararigas G; Fliegner D; Gustafsson J-A; Regitz-Zagrosek V
Article: BREAST CANCER RESEARCH. 2011;13(2):R43
Estrogen receptor β represses Akt signaling in breast cancer cells via downregulation of HER2/HER3 and upregulation of PTEN: implications for tamoxifen sensitivity
Lindberg K; Helguero LA; Omoto Y; Gustafsson J-A; Haldosen L-A
Article: FEBS LETTERS. 2011;585(5):744-748
CIDEA interacts with liver X receptors in white fat cells
Kulyte A; Pettersson AT; Antonson P; Stenson BM; Langin D; Gustafsson J-A; Staels B; Ryden M; Arner P; Laurencikiene J
Article: HYPERTENSION. 2011;57(3):648-654
Estrogen receptor-beta signals left ventricular hypertrophy sex differences in normotensive deoxycorticosterone acetate-salt mice.
Gürgen D; Hegner B; Kusch A; Catar R; Chaykovska L; Hoff U; Gross V; Slowinski T; da Costa Goncalves AC; Kintscher U; Gustafsson J-Å; Luft FC; Dragun D
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(1):403-408
Both liver-X receptor (LXR) isoforms control energy expenditure by regulating Brown Adipose Tissue activity
Korach-Andre M; Archer A; Barros RP; Parini P; Gustafsson J-A
Article: MOLECULAR & CELLULAR PROTEOMICS. 2011;10(1):M110.002170
Quantitative Proteomics and Transcriptomics Addressing the Estrogen Receptor Subtype-mediated Effects in T47D Breast Cancer Cells Exposed to the Phytoestrogen Genistein
Sotoca AM; Gelpke MDS; Boeren S; Stroem A; Gustafsson J-A; Murk AJ; Rietjens IMCM; Vervoort J
Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2011;89(1):44-55
Estrogen Receptors: Therapies Targeted to Receptor Subtypes
Nilsson S; Gustafsson J-A
Article: PLOS ONE. 2010;5(9):e13087
Decreased Fat Storage by Lactobacillus Paracasei Is Associated with Increased Levels of Angiopoietin-Like 4 Protein (ANGPTL4)
Aronsson L; Huang Y; Parini P; Korach-Andre M; Hakansson J; Gustafsson J-A; Pettersson S; Arulampalam V; Rafter J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(33):14763-14768
Estrogen-dependent gallbladder carcinogenesis in LXRβ^-/- female mice
Gabbi C; Kim H-J; Barros R; Korach-Andre M; Warner M; Gustafsson J-A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(27):12305-12310
Liver X receptor β and thyroid hormone receptor α in brain cortical layering
Tan X-J; Fan X-T; Kim H-J; Butler R; Webb P; Warner M; Gustafsson J-A
Article: MOLECULAR & CELLULAR PROTEOMICS. 2010;9(7):1411-1422
Proteomics Analysis of the Estrogen Receptor α Receptosome
Nalvarte I; Schwend T; Gustafsson J-A
Article: CANCER RESEARCH. 2010;70(12):5174-5183
Genome-Wide Mapping of Estrogen Receptor-β-Binding Regions Reveals Extensive Cross-Talk with Transcription Factor Activator Protein-1
Zhao C; Gao H; Liu Y; Papoutsi Z; Jaffrey S; Gustafsson J-A; Dahlman-Wright K
Article: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. 2010;69(6):593-605
Neuropathologic and Biochemical Changes During Disease Progression in Liver X Receptor β^-/- Mice, A Model of Adult Neuron Disease
Bigini P; Steffensen KR; Ferrario A; Diomede L; Ferrara G; Barbera S; Salzano S; Fumagalli E; Ghezzi P; Mennini T; Gustafsson J-A
Article: AMERICAN JOURNAL OF PHYSIOLOGY. REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2010;298(6):R1597-R1606
Female sex and estrogen receptor-β attenuate cardiac remodeling and apoptosis in pressure overload
Fliegner D; Schubert C; Penkalla A; Witt H; Kararigas G; Dworatzek E; Staub E; Martus P; Noppinger PR; Kintscher U; Gustafsson J-A; Regitz-Zagrosek V
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;396(1):63-66
The role of estrogen receptor β (ERβ) in malignant diseases-A new potential target for antiproliferative drugs in prevention and treatment of cancer
Warner M; Gustafsson J-A
Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2010;99(5):763-769
Late effects of early growth hormone treatment in Down syndrome.
Myrelid Å; Bergman S; Elfvik Strömberg M; Jonsson B; Nyberg F; Gustafsson J; Annerén G
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(14):6453-6458
Gonadotropin-positive pituitary tumors accompanied by ovarian tumors in aging female ERβ^-/- mice
Fan X; Gabbi C; Kim H-J; Cheng G; Andersson LC; Warner M; Gustafsson J-A
Article: BREAST CANCER RESEARCH AND TREATMENT. 2010;120(2):317-326
SOX9 mediates the retinoic acid-induced HES-1 gene expression in human breast cancer cells
Muller P; Crofts JD; Newman BS; Bridgewater LC; Lin C-Y; Gustafsson J-A; Stroem A
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2010;1801(4):421-429
ADD1/SREBP1c activates the PGC1-α promoter in brown adipocytes
Hao Q; Hansen JB; Petersen RK; Hallenborg P; Jorgensen C; Cinti S; Larsen PJ; Steffensen KR; Wang H; Collins S; Wang J; Gustafsson J-A; Madsen L; Kristiansen K
Article: PLOS ONE. 2010;5(3):e9678
Levels of 17β-Estradiol Receptors Expressed in Embryonic and Adult Zebrafish Following In Vivo Treatment of Natural or Synthetic Ligands
Chandrasekar G; Archer A; Gustafsson J-A; Lendahl MA
Article: GENES & DEVELOPMENT. 2010;24(4):381-395
GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRβ in the hepatic acute phase response
Venteclef N; Jakobsson T; Ehrlund A; Damdimopoulos A; Mikkonen L; Ellis E; Nilsson L-M; Parini P; Janne OA; Gustafsson J-A; Steffensen KR; Treuter E
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;392(3):436-441
LXRbeta deficient mice have reduced hepatic insulin clearance during hyperinsulinemic euglucemic clamp.
Holm S; Voshol PJ; Gustafsson J-A; Nebb HI
Article: CANCER RESEARCH. 2010;70(3):1265-1274
RBCK1 Drives Breast Cancer Cell Proliferation by Promoting Transcription of Estrogen Receptor α and Cyclin B1
Gustafsson N; Zhao C; Gustafsson J-A; Dahlman-Wright K
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2010;298(2):E167-E178
Separate and overlapping metabolic functions of LXRα and LXRβ in C57Bl/6 female mice
Korach-Andre M; Parini P; Larsson L; Arner A; Steffensen KR; Gustafsson J-A
Article: JOURNAL OF CELLULAR PHYSIOLOGY. 2010;222(1):156-167
Expression of Estrogen Receptor β Increases Integrin α1 and Integrin β1 Levels and Enhances Adhesion of Breast Cancer Cells
Lindberg K; Strom A; Lock JG; Gustafsson J-A; Haldosen L-A; Helguero LA
Article: NATURE MEDICINE. 2010;16(1):98-105
Tumor-mediated liver X receptor-α activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses
Villablanca EJ; Raccosta L; Zhou D; Fontana R; Maggioni D; Negro A; Sanvito F; Ponzoni M; Valentinis B; Bregni M; Prinetti A; Steffensen KR; Sonnino S; Gustafsson J-A; Doglioni C; Bordignon C; Traversari C; Russo V
Article: MOLECULAR PHARMACOLOGY. 2010;77(1):79-86
The Human ADFP Gene Is a Direct Liver-X-Receptor (LXR) Target Gene and Differentially Regulated by Synthetic LXR Ligands
Kotokorpi P; Venteclef N; Ellis E; Gustafsson J-A; Mode A
Article: JOURNAL OF ENDOCRINOLOGY. 2009;203(3):349-356
In vivo activation of gene transcription via oestrogen response elements by a raloxifene analogue
Engdahl C; Jochems C; Gustafsson J-A; van der Saag PT; Carlsten H; Lagerquist MK
Article: MOLECULAR ENDOCRINOLOGY. 2009;23(12):1973-1982
Rapid Regulation of K_ATP Channel Activity by 17β-Estradiol in Pancreatic β-Cells Involves the Estrogen Receptor β and the Atrial Natriuretic Peptide Receptor
Soriano S; Ropero AB; Alonso-Magdalena P; Ripoll C; Quesada I; Gassner B; Kuhn M; Gustafsson J-A; Nadal A
Article: SHOCK. 2009;32(5):548-553
LIVER X RECEPTOR AGONIST GW3965 DOSE-DEPENDENTLY REGULATES LPS-MEDIATED LIVER INJURY AND MODULATES POSTTRANSCRIPTIONAL TNF-α PRODUCTION AND P38 MITOGEN-ACTIVATED PROTEIN KINASE ACTIVATION IN LIVER MACROPHAGES
Wang YY; Dahle MK; Steffensen KR; Reinholt FP; Collins JL; Thiemermann C; Aasen AO; Gustafsson J-A; Wang JE
Article: CELL STEM CELL. 2009;5(4):409-419
Liver X Receptors and Oxysterols Promote Ventral Midbrain Neurogenesis In Vivo and in Human Embryonic Stem Cells
Sacchetti P; Sousa KM; Hall AC; Liste I; Steffensen KR; Theofilopoulos S; Parish CL; Hazenberg C; Ahrlund-Richter L; Hovatta O; Gustafsson J-A; Arenas E
Article: ENDOCRINE. 2009;36(2):224-232
Microarray analysis of altered gene expression in ERβ-overexpressing HEK293 cells
Zhao C; Putnik M; Gustafsson J-A; Dahlman-Wright K
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2009;1793(10):1588-1596
The human thioredoxin reductase-1 splice variant TXNRD1_v3 is an atypical inducer of cytoplasmic filaments and cell membrane filopodia
Damdimopoulou PE; Miranda-Vizuete A; Arner ESJ; Gustafsson J-A; Damdimopoulos AE
Article: OSTEOARTHRITIS AND CARTILAGE. 2009;17(10):1356-1361
Development of osteoarthritic features in estrogen receptor knockout mice
Sniekers YH; van Osch GJVM; Ederveen AGH; Inzunza J; Gustafsson J-A; van Leeuwen JPTM; Weinans H
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2009;29(10):1488-1495
Rexinoid Bexarotene Modulates Triglyceride but not Cholesterol Metabolism via Gene-Specific Permissivity of the RXR/LXR Heterodimer in the Liver
Lalloyer F; Pedersen TA; Gross B; Lestavel S; Yous S; Vallez E; Gustafsson J-A; Mandrup S; Fievet C; Staels B; Tailleux A
Article: PLOS ONE. 2009;4(9):e7266
Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase.
Hellemans KH; Hannaert J-C; Denys B; Steffensen KR; Raemdonck C; Martens GA; Van Veldhoven PP; Gustafsson J-A; Pipeleers D
Article: BMC GENETICS. 2009;10:55
Effects of two common polymorphisms in the 3′ untranslated regions of estrogen receptor β on mRNA stability and translatability
Putnik M; Zhao C; Gustafsson J-A; Dahlman-Wright K
Article: CARCINOGENESIS. 2009;30(9):1591-1596
Genetic mapping of Mom5, a novel modifier of Apc^Min-induced intestinal tumorigenesis
Oikarinen SI; Cleveland AG; Cork KM; Bynote KK; Rafter JJ; Gustafsson J-A; Mutanen M; Gould KA
Article: CARCINOGENESIS. 2009;30(9):1581-1590
Disruption of estrogen receptor signaling enhances intestinal neoplasia in Apc^Min/+ mice
Cleveland AG; Oikarinen SI; Bynote KK; Marttinen M; Rafter JJ; Gustafsson J-A; Roy SK; Pitot HC; Korach KS; Lubahn DB; Mutanen M; Gould KA
Article: CANCER RESEARCH. 2009;69(15):6100-6106
Tumor Repressive Functions of Estrogen Receptor β in SW480 Colon Cancer Cells
Hartman J; Edvardsson K; Lindberg K; Zhao C; Williams C; Strom A; Gustafsson J-A
Article: HUMAN MOLECULAR GENETICS. 2009;18(15):2802-2812
Functional interaction of DYX1C1 with estrogen receptors suggests involvement of hormonal pathways in dyslexia
Massinen S; Tammimies K; Tapia-Paez I; Matsson H; Hokkanen M-E; Soderberg O; Landegren U; Castren E; Gustafsson J-A; Treuter E; Kere J
Article: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 2009;43(1-2):65-72
Binding of estrogen receptor α/β heterodimers to chromatin in MCF-7 cells
Papoutsi Z; Zhao C; Putnik M; Gustafsson J-A; Dahlman-Wright K
Article: ENDOCRINE. 2009;36(1):169-177
Effects of estrogen receptor α and β gene deletion on estrogenic induction of progesterone receptors in the locus coeruleus in female mice
Helena C; Gustafsson J-A; Korach K; Pfaff D; Anselmo-Franci JA; Ogawa S
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2009;297(1):E124-E133
Participation of ERα and ERβ in glucose homeostasis in skeletal muscle and white adipose tissue
Barros RPA; Gabbi C; Morani A; Warner M; Gustafsson J-A
Article: JOURNAL OF ENDOCRINOLOGY. 2009;201(3):397-406
Inner ear pathology and loss of hearing in estrogen receptor-β deficient mice
Simonoska R; Stenberg AE; Duan M; Yakimchuk K; Fridberger A; Sahlin L; Gustafsson J-A; Hultcrantz M
Article: JOURNAL OF CLINICAL INVESTIGATION. 2009;119(6):1626-1637
Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in mice
Korf H; Vander Beken S; Romano M; Steffensen KR; Stijlemans B; Gustafsson J-A; Grooten J; Huygen K
Article: MOLECULAR CELL. 2009;34(4):510-518
GPS2 Is Required for Cholesterol Efflux by Triggering Histone Demethylation, LXR Recruitment, and Coregulator Assembly at the ABCG1 Locus
Jakobsson T; Venteclef N; Toresson G; Damdimopoulos AE; Ehrlund A; Lou X; Sanyal S; Steffensen KR; Gustafsson J-A; Treuter E
Article: PAIN. 2009;143(1-2):37-40
Ablation of estrogen receptor α or β eliminates sex differences in mechanical pain threshold in normal and inflamed mice
Li L; Fan X; Warner M; Xu X-J; Gustafsson J-A; Wiesenfeld-Hallin Z
Article: MOLECULAR AND CELLULAR BIOLOGY. 2009;29(8):2230-2242
E3 Ubiquitin Ligase RNF31 Cooperates with DAX-1 in Transcriptional Repression of Steroidogenesis
Ehrlund A; Anthonisen EH; Gustafsson N; Venteclef N; Remen KR; Damdimopoulos AE; Galeeva A; Pelto-Huikko M; Lalli E; Steffensen KR; Gustafsson J-A; Treuter E
Article: CARCINOGENESIS. 2009;30(4):575-579
The oxysterol receptor LXR inhibits proliferation of human breast cancer cells
Vedin L-L; Lewandowski SA; Parini P; Gustafsson J-A; Steffensen KR
Article: BMC MEDICAL GENETICS. 2009;10:27
Functional and genetic analysis in type 2 diabetes of Liver X receptor alleles - a cohort study
Dahlman I; Nilsson M; Gu HF; Lecoeur C; Efendic S; Ostenson CG; Brismar K; Gustafsson J-A; Froguel P; Vaxillaire M; Dahlman-Wright K; Steffensen KR
Article: JOURNAL OF ENDOCRINOLOGY. 2009;200(3):311-319
Estrogen-dependent downregulation of hairy and enhancer of split homolog-1 gene expression in breast cancer cells is mediated via a 3′ distal element
Muller P; Merrell KW; Crofts JD; Ronnlund C; Lin C-Y; Gustafsson J-A; Strom A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(8):2859-2863
A role for epithelial-mesenchymal transition in the etiology of benign prostatic hyperplasia
Alonso-Magdalena P; Broessner C; Reiner A; Cheng G; Sugiyama N; Warner M; Gustafsson J-A
Article: PHYSIOLOGY AND BEHAVIOR. 2009;96(2):300-306
Effect of ER-β gene disruption on estrogenic regulation of anxiety in female mice
Tomihara K; Soga T; Nomura M; Korach KS; Gustafsson J-A; Pfaff DW; Ogawa S
Article: ENDOCRINOLOGY. 2009;150(2):1061-1068
Hormonal Regulation of Prolactin Cell Development in the Fetal Pituitary Gland of the Mouse
Ogasawara K; Nogami H; Tsuda MC; Gustafsson J-A; Korach KS; Ogawa S; Harigaya T; Hisano S
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2009;1791(2):140-147
Regulation of hepatic fatty acid elongase 5 by LXRα-SREBP-1c
Qin Y; Dalen KT; Gustafsson J-A; Nebb HI
Article: MOLECULAR PSYCHIATRY. 2009;14(2):223-117
Spatiotemporal dynamics of the expression of estrogen receptors in the postnatal mouse brain
Sugiyama N; Andersson S; Lathe R; Fan X; Alonso-Magdalena P; Schwend T; Nalvarte I; Warner M; Gustafsson J-A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(2):558-563
Stromal growth and epithelial cell proliferation in ventral prostates of liver X receptor knockout mice
Kim H-J; Andersson LC; Bouton D; Warner M; Gustafsson J-A
Article: BREAST CANCER RESEARCH. 2009;11(6):R79
Hes-6, an inhibitor of Hes-1, is regulated by 17β-estradiol and promotes breast cancer cell proliferation
Hartman J; Lam EW-F; Gustafsson J-A; Strom A
Article: BREAST CANCER RESEARCH. 2009;11(3):R26
Gene expression in murine mammary epithelial stem cell-like cells shows similarities to human breast cancer gene expression
Williams C; Helguero L; Edvardsson K; Haldosen L-A; Gustafsson J-A
Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2008;112(4-5):171-178
Phytoestrogen-mediated inhibition of proliferation of the human T47D breast cancer cells depends on the ERα/ERβ ratio
Sotoca AM; Ratman D; van der Saag P; Strom A; Gustafsson JA; Vervoort J; Rietjens IMCM; Murk AJ
Article: JOURNAL OF ENDOCRINOLOGY. 2008;199(2):X1
The estrogen receptor {alpha}-selective agonist propyl pyrazole triol improves glucose tolerance in ob/ob mice; potential molecular mechanisms.
Lundholm L; Bryzgalova G; Gao H; Portwood N; Fält S; Berndt KD; Dicker A; Galuska D; Zierath JR; Gustafsson J-Å; Efendic S; Dahlman-Wright K; Khan A
Article: JOURNAL OF ENDOCRINOLOGY. 2008;199(2):275-286
The estrogen receptor α-selective agonist propyl pyrazole triol improves glucose tolerance in ob/ob mice; potential molecular mechanisms
Lundholm L; Bryzgalova G; Gao H; Portwood N; Falt S; Berndt KD; Dicker A; Galuska D; Zierath IR; Gustafsson JA; Efendic S; Dahlman-Wright K; Khan A
Article: CANCER RESEARCH. 2008;68(21):8695-8704
Different Roles of Estrogen Receptors α and β in the Regulation of E-Cadherin Protein Levels in a Mouse Mammary Epithelial Cell Line
Helguero LA; Lindberg K; Gardmo C; Schwend T; Gustafsson J-A; Haldosen L-A
Article: PHARMACOGENETICS AND GENOMICS. 2008;18(11):967-975
Estrogen receptor alpha gene variants associate with type 2 diabetes and fasting plasma glucose
Dahlman I; Vaxillaire M; Nilsson M; Lecoeur C; Gu HF; Cavalcanti-Proenca C; Efendic S; Ostenson CG; Brismar K; Charpentler G; Gustafsson J-A; Froguel P; Dahlman-Wright K; Steffensen KR
Article: FOOD AND CHEMICAL TOXICOLOGY. 2008;46(10):3268-3278
Characterisation of bioactive compounds in infant formulas using immobilised recombinant estrogen receptor-α affinity columns
Riu A; Balaguer P; Perdu E; Pandelova M; Piccinelli R; Gustafsson J-A; Ledercq C; Schramm K-W; Dagnino S; Debrauwer L; Cravedi J-P; Zalko D
Article: TOXICOLOGICAL SCIENCES. 2008;105(2):303-311
Influence of cellular ERα/ERβ ratio on the ERα-agonist induced proliferation of human T47D breast cancer cells
Covaleda AMS; Van den Berg H; Vervoort J; Van der Saag P; Strom A; Gustafsson J-A; Rietjens I; Murk AJ
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2008;295(4):E904-E912
Mechanisms of antidiabetogenic and body weight-lowering effects of estrogen in high-fat diet-fed mice
Bryzgalova G; Lundholm L; Portwood N; Gustafsson J-A; Khan A; Efendic S; Dahlman-Wright K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(39):15052-15057
Pancreatic exocrine insufficiency in LXRβ^-/- mice is associated with a reduction in aquaporin-1 expression
Gabbi C; Kim H-J; Hultenby K; Bouton D; Toresson G; Warner M; Gustafsson J-A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(36):13445-13450
Expression of liver X receptor β is essential for formation of superficial cortical layers and migration of later-born neurons
Fan X; Kim H-J; Bouton D; Warner M; Gustafsson J-A
Article: NEUROBIOLOGY OF DISEASE. 2008;31(3):386-394
Tau hyperphosphorylation correlates with reduced methylation of protein phosphatase 2A
Zhou X-W; Gustafsson J-A; Tanila H; Bjorkdahl C; Liu R; Winblad B; Pei J-J
Article: FERTILITY AND STERILITY. 2008;90(1):44-48
Key lipogenic gene expression can be decreased by estrogen in human adipose tissue
Lundholm L; Zang H; Hirschberg AL; Gustafsson J-A; Arner P; Dahlman-Wright K
Article: PLOS GENETICS. 2008;4(6):e1000108
Metabolic Actions of Estrogen Receptor Beta (ERβ) are Mediated by a Negative Cross-Talk with PPARγ
Foryst-Ludwig A; Clemenz M; Hohmann S; Hartge M; Sprang C; Frost N; Krikov M; Bhanot S; Barros R; Morani A; Gustafsson J-A; Unger T; Kintscher U
Article: ENDOCRINOLOGY. 2008;149(6):2917-2922
Estrogen receptor β selective ligand 5α-androstane-3β, 17β-diol stimulates spermatogonial deoxyribonucleic acid synthesis in rat seminiferous epithelium in vitro
Wahlgren A; Svechnikov K; Strand M-L; Jahnukainen K; Parvinen M; Gustafsson J-A; Soder O
Article: PSYCHONEUROENDOCRINOLOGY. 2008;33(5):634-642
Estrogen receptors α and β mediate different aspects of the facilitatory effects of female cues on male risk taking
Kavaliers M; Devidze N; Choleris E; Fudge M; Gustafsson J-A; Korach KS; Pfaff DW; Ogawa S
Article: CELLULAR MICROBIOLOGY. 2008;10(5):1093-1103
Gut flora, Toll-like receptors and nuclear receptors:: a tripartite communication that tunes innate immunity in large intestine
Lundin A; Bok CM; Aronsson L; Bjorkholm B; Gustafsson J-A; Pott S; Arulampalam V; Hibberd M; Rafter J; Pettersson S
Article: EUROPEAN JOURNAL OF CANCER. 2008;44(7):1007-1014
Tamoxifen exposure in relation to gastric adenocarcinoma development
Chandanos E; Lindblad M; Rubio CA; Jia C; Warner M; Gustafsson J-A; Lagergren J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2008;368(3):569-574
FMS-like tyrosine kinase 3 interacts with the glucocorticoid receptor complex and affects glucocorticoid dependent signaling
Asadi A; Hedman E; Widen C; Zilliacus J; Gustafsson J-A; Wikstrom A-C
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2008;283(14):8995-9001
RAP250 is a coactivator in the transforming growth factor β signaling pathway that interacts with smad2 and smad3
Antonson P; Jakobsson T; Almloef T; Guldevall K; Steffensen KR; Gustafsson J-A
Article: JOURNAL OF CLINICAL INVESTIGATION. 2008;118(4):1563-1570
Estrogen receptor β protects against acoustic trauma in mice
Meltser I; Tahera Y; Simpson E; Hultcrantz M; Charitidi K; Gustafsson J-A; Canlon B
Article: DEVELOPMENTAL DYNAMICS. 2008;237(4):1090-1098
Transcriptional activity and developmental expression of liver X receptor (lxr) in zebrafish
Archer A; Lauter G; Hauptmann G; Mode A; Gustafsson J-A
Article: JOURNAL OF ENDOCRINOLOGY. 2008;196(3):547-557
Effects of estrogen on gene expression profiles in mouse hypothalamus and white adipose tissue:: target genes include glutathione peroxidase 3 and cell death-inducing, DNA fragmentation factor, α-subunit-like effector A
Lundholm L; Putnik M; Otsukil M; Andersson S; Ohisson C; Gustafsson J-A; Dahlman-Wright K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(7):2604-2609
The genome landscape of ERα- and ERβ-binding DNA regions
Liu Y; Gao H; Marstrand TT; Strom A; Valen E; Sandelin A; Gustafsson J-A; Dahlman-Wright K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(6):2094-2099
Liver X receptor β (LXRβ):: A link between β-sitosterol and amyotrophic lateral sclerosis-Parkinson's dementia
Kim H-J; Fan X; Gabbi C; Yakimchuk K; Parini P; Warner M; Gustafsson J-A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(6):1943-1948
Enterococcus faecalis from newborn babies regulate endogenous PPARγ activity and IL-10 levels in colonic epithelial cells
Are A; Aronsson L; Wang S; Greicius G; Lee YK; Gustafsson J-A; Pettersson S; Arulampalam V
Article: ONCOGENE. 2008;27(7):1019-1032
A genome-wide study of the repressive effects of estrogen receptor beta on estrogen receptor alpha signaling in breast cancer cells
Williams C; Edvardsson K; Lewandowski SA; Stroem A; Gustafsson J-A
Article: MOLECULAR ENDOCRINOLOGY. 2008;22(1):10-22
Genome-wide identification of estrogen receptor α-binding sites in mouse liver
Gao H; Falt S; Sandelin A; Gustafsson J-A; Dahlman-Wright K
Article: ENDOCRINOLOGY. 2008;149(1):339-345
Ligands differentially modify the nuclear mobility of estrogen receptors α and β
Damdimopoulos AE; Spyrou G; Gustafsson J-A
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2008;12(1):241-257
Phosphorylated PP2A (tyrosine 307) is associated with Alzheimer neurofibrillary pathology
Liu R; Zhou X-W; Tanila H; Bjorkdahl C; Wang J-Z; Guan Z-Z; Cao Y; Gustafsson J-A; Winblad B; Pei J-J
Article: MOLECULAR AND CELLULAR BIOLOGY. 2008;28(2):784-793
Expression levels of estrogen receptor β are modulated by components of the molecular clock
Cai W; Rambaud J; Teboul M; Masse I; Benoit G; Gustafsson J-A; Delaunay F; Laudet V; Pongratz I
Article: GASTRIC CANCER. 2008;11(3):168-174
Endogenous estrogen exposure in relation to distribution of histological type and estrogen receptors in gastric adenocarcinoma
Chandanos E; Rubio CA; Lindbland M; Jia C; Tsolakis AV; Warner M; Gustafsson J-A; Lagergren J
Article: AMERICAN JOURNAL OF PHYSIOLOGY. REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2008;294(1):R112-R120
Functional characterization and sex differences in small mesenteric arteries of the estrogen receptor-β knockout mouse
Douglas G; Cruz MN; Poston L; Gustafsson J-A; Kublickiene K
Article: BMC MEDICAL GENETICS. 2007;8:73
Impact of estrogen receptor gene polymorphisms and mRNA levels on obesity and lipolysis - a cohort study
Nilsson M; Dahlman I; Jiao H; Gustafsson J-A; Arner P; Dahlman-Wright K
Article: ENDOCRINOLOGY. 2007;148(12):5688-5695
Identification of target cells for the genomic effects of Estrogens in bone
Windahl SH; Lagerquist MK; Andersson N; Jochems C; Kallkopf A; Hakansson C; Inzunza J; Gustafsson J-A; Van der Saag PT; Carlsten H; Pettersson K; Ohlsson C
Article: CLINICAL LIPIDOLOGY. 2007;2(6):603-607
Targeting liver X receptor β:: a new therapeutic approach to prevent atherosclerosis?
Parini P; Gustafsson J-A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2007;104(40):15665-15670
Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis
Sanyal S; Bavner A; Haroniti A; Nilsson L-M; Lundasen T; Rehnmark S; Witt MR; Einarsson C; Talianidis I; Gustafsson J-A; Treuter E
Article: MOLECULAR PHARMACOLOGY. 2007;72(4):947-955
Physiological differences between human and rat primary hepatocytes in response to liver X receptor activation by 3-[3-[N-(2-chloro-3-trifluoromethylbenzyl)-(2,2diphenylethyl)amino]propyloxy] phenylacetic acid hydrochloride (GW3965)
Kotokorpi P; Ellis E; Parini P; Nilsson L-M; Strom S; Steffensen KR; Gustafsson J-A; Mode A
Article: BIOCHEMICAL JOURNAL. 2007;406(2):343-353
Co-planar 3,3′,4,4′5-pentachlorinated biphenyl and non-co-planar 2,2′,4,6,6′-pentachlorinated biphenyl differentially induce recruitment of oestrogen receptor α to aryl hydrocarbon receptor target genes
Matthews J; Wihlen B; Heldring N; MacPherson L; Helguero L; Treuter E; Haldosen L-A; Gustafsson J-A
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2007;22(9):2571-2577
Association between oestrogen receptor α gene polymorphism and mortality in female end-stage renal disease patients
Kato S; Lindholm B; Axelsson J; Qureshi RA; Barany P; Heimburger O; Gustafsson J-A; Stenvinkel P; Nordfors L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2007;104(34):13696-13701
Estrogen receptor β is essential for sprouting of nociceptive primary afferents and for morphogenesis and maintenance of the dorsal horn interneurons
Fan X; Kim H-J; Warner M; Gustafsson J-A
Article: BIOCHEMICAL JOURNAL. 2007;405(1):31-39
Molecular basis for repression of liver X receptor-mediated gene transcription by receptor-interacting protein 140
Jakobsson T; Osman W; Gustafsson J-A; Zilliacus J; Warnmark A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2007;104(23):9806-9809
Estrogen receptor β-deficient female mice develop a bladder phenotype resembling human interstitial cystitis
Imamov O; Yakimchuk K; Morani A; Schwend T; Wada-Hiraike O; Razumov S; Warner M; Gustafsson J-A
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2007;1773(6):687-690
Nuclear immobilization of DsRed1 tagged proteins: A novel tool for studying DNA-protein interactions?
Damdimopoulos AE; Gustafsson J-A; Spyrou G
Article: INTERNATIONAL JOURNAL OF OBESITY. 2007;31(6):900-907
Oestrogen receptor α gene expression levels are reduced in obese compared to normal weight females
Nilsson M; Dahlman I; Ryden M; Nordstrom EA; Gustafsson J-A; Arner P; Dahlman-Wright K
Article: MENOPAUSE. 2007;14(3):468-473
Isoflavone treatment for acute menopausal symptoms
Cheng G; Wilczek B; Warner M; Gustafsson J-A; Landgren B-M
Article: CANCER RESEARCH. 2007;67(8):3955-3962
Estrogen receptor β2 negatively regulates the transactivation of estrogen receptor α in human breast cancer cells
Zhao C; Matthews J; Tujague M; Wan J; Strom A; Toresson G; Lam EW-F; Cheng G; Gustafsson J-A; Dahlman-Wright K
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2007;282(14):10449-10455
Structural insights into corepressor recognition by antagonist-bound estrogen receptors
Heldring N; Pawson T; McDonnell D; Treuter E; Gustafsson J-A; Pike ACW
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2007;104(2):600-605
Ovarian wedge resection restores fertility in estrogen receptor β knockout (ERβ^-/-) mice
Inzunza J; Morani A; Cheng G; Warner M; Hreinsson J; Gustafsson J-A; Hovatta O
Article: BREAST CANCER RESEARCH. 2007;9(2):R25
Inhibitory effects of estrogen receptor beta on specific hormone-responsive gene expression and association with disease outcome in primary breast cancer
Lin C-Y; Stroem A; Kong SL; Kietz S; Thomsen JS; Tee JBS; Vega VB; Miller LD; Smeds J; Bergh J; Gustafsson J-A; Liu ET
Article: NUCLEIC ACIDS RESEARCH (NAR). 2007;35(14):4858-4868
Elk1 and SRF transcription factors convey basal transcription and mediate glucose response via their binding sites in the human LXRB gene promoter
Nilsson M; Dahlman-Wright K; Karelmo C; Gustafsson J-A; Steffensen KR
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006;103(51):19338-19343
Estrogen receptor β expression in the embryonic brain regulates development of calretinin-immunoreactive GABAergic interneurons
Fan X; Warner M; Gustafsson J-A
Article: JOURNAL OF PHYSIOLOGY. 2006;577(3):945-955
The oestrogen receptor β contributes to sex related differences in endothelial function of murine small arteries via EDHF
Luksha L; Poston L; Gustafsson J-A; Hultenby K; Kublickiene K
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2006;49(25):7357-7365
Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors α and β
Roelens F; Heldring N; Dhooge W; Bengtsson M; Comhaire F; Gustafsson J-A; Treuter E; De Keukeleire D
Article: PHARMACOGENETICS AND GENOMICS. 2006;16(12):881-889
Liver X receptor gene polymorphisms and adipose tissue expression levels in obesity
Dahlman I; Nilsson M; Jiao H; Hoffstedt J; Lindgren CM; Humphreys K; Kere J; Gustafsson J-A; Arner P; Dahlman-Wright K
Article: CANCER RESEARCH. 2006;66(23):11207-11213
Estrogen receptor β inhibits angiogenesis and growth of T47D breast cancer xenografts
Hartman J; Lindberg K; Morani A; Inzunza J; Strom A; Gustafsson J-A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006;103(48):18350-18355
Role of estrogen receptor β in uterine stroma and epithelium:: Insights from estrogen receptor β^-/- mice
Wada-Hiraike O; Hiraike H; Okinaga H; Imamov O; Barros RPA; Morani A; Omoto Y; Warner M; Gustafsson J-K
Article: MOLECULAR PHARMACOLOGY. 2006;70(4):1340-1349
Liver X receptor (LXR)-β regulation in LXRα-deficient mice:: Implications for therapeutic targeting
Quinet EM; Savio DA; Halpern AR; Chen L; Schuster GU; Gustafsson J-A; Basso MD; Nambi P
Article: GENES, BRAIN AND BEHAVIOR. 2006;5(7):528-539
Involvement of estrogen receptor α, β and oxytocin in social discrimination:: a detailed behavioral analysis with knockout female mice
Choleris E; Ogawa S; Kavaliers M; Gustafsson J-A; Korach KS; Muglia LJ; Pfaff DW
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;348(1):176-182
Improved metabolic control by depletion of Liver X Receptors in mice
Schuster GU; Johansson L; Kietz S; Stulnig TM; Parini P; Gustafsson J-A
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2006;256(1-2):9-16
Reduced fertility and inability of oocytes to resume meiosis in mice deficient of the Lxr genes
Steffensen KR; Robertson K; Gustafsson J-A; Andersen CY
Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2006;21(8):1276-1287
Cholesterol-sensing receptors, liver X receptor α and β, have novel and distinct roles in osteoclast differentiation and activation
Robertson KM; Norgard M; Windahl SH; Hultenby K; Ohlsson C; Andersson G; Gustafsson J-A
Article: ENDOCRINOLOGY. 2006;147(7):3249-3259
DAX-1 expression is regulated during mammary epithelial cell differentiation
Helguero LA; Faulds MH; Forster C; Gustafsson J-A; Haldosen L-A
Article: MOLECULAR ENDOCRINOLOGY. 2006;20(6):1287-1299
Long-term administration of estradiol decreases expression of hepatic lipogenic genes and improves insulin sensitivity in ob/ob mice: A possible mechanism is through direct regulation of signal transducer and activator of transcription 3
Gao H; Bryzgalova G; Hedman E; Khan A; Efendic S; Gustafsson JA; Dahlman-Wright K
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;343(3):707-711
False positives in MALDI-TOF detection of ERbeta in mitochondria.
Schwend T; Gustafsson J-A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006;103(18):7165-7169
Lung dysfunction causes systemic hypoxia in estrogen receptor β knockout (ERβ^-/-) mice
Morani A; Barros RPA; Imamov O; Hultenby K; Arner A; Warner M; Gustafssonn J
Article: PROTEOMICS. 2006;6(10):3114-3126
Proteomic identification of glucocorticoid receptor interacting proteins
Hedman E; Widen C; Asadi A; Dinnetz I; Schroder WP; Gustafsson J-K; Wikstrom A-C
Article: PHARMACOGENETICS AND GENOMICS. 2006;16(5):379-383
Functional characterization of a novel variant of estrogen receptor beta identified in screening of DNA derived from African Americans
Zhao C; Gustafsson J; Dahlman-Wright K
Article: OBESITY. 2006;14(4):662-672
Dihydrotestosterone treatment results in obesity and altered lipid metabolism in orchidectomized mice
Moverare-Skrtic S; Venken K; Andersson N; Lindberg MK; Svensson J; Swanson C; Vanderschueren D; Oscarsson J; Gustafsson J-A; Ohlsson C
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2006;23(7):1860-1868
Estrogen receptor-β gene disruption potentiates estrogen-inducible aggression but not sexual behaviour in male mice
Nomura M; Andersson S; Korach KS; Gustafsson J; Pfaff DW; Ogawa S
Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2006;317(1):395-401
Pitavastatin effect on ATP binding cassette A1-mediated lipid efflux from macrophages:: Evidence for liver X receptor (LXR)-dependent and LXR-independent mechanisms of activation by cAMP
Zanotti I; Potì F; Favari E; Steffensen KR; Gustafsson J; Bernini F
Article: CLINICAL CANCER RESEARCH. 2006;12(6):1936-1941
Estrogen receptor β polymorphism is associated with prostate cancer risk
Thellenberg-Karlsson C; Lindström S; Malmer B; Wiklund F; Augustsson-Bälter K; Adami HO; Stattin P; Nilsson M; Dahlman-Wright K; Gustafsson J; Grönberg H
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2006;83(3):592-600
Soy-isoflavone-enriched foods and markers of lipid and glucose metabolism in postmenopausal women:: interactions with genotype and equol production
Hall WL; Vafeiadou K; Hallund J; Bugel S; Reimann M; Koebnick C; Zunft HJF; Ferrari M; Branca F; Dadd T; Talbot D; Powell J; Minihane AM; Cassidy A; Nilsson M; Dahlman-Wright K; Gustafsson J; Williams CM
Article: DIABETOLOGIA. 2006;49(3):588-597
Evidence that oestrogen receptor-α plays an important role in the regulation of glucose homeostasis in mice:: insulin sensitivity in the liver
Bryzgalova G; Gao H; Ahren B; Zierath JR; Galuska D; Steiler TL; Dahlman-Wright K; Nilsson S; Gustafsson J; Efendic S; Khan A
Article: MOLECULAR ENDOCRINOLOGY. 2006;20(3):534-543
Estrogen receptor (ER) β modulates ERα-mediated transcriptional activation by altering the recruitment of c-Fos and c-Jun to estrogen-responsive promoters
Matthews J; Wihlén B; Tujague M; Wan JH; Ström A; Gustafsson J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006;103(8):2959-2964
Role of estrogen receptor β in colonic epithelium
Wada-Hiraike O; Imamov O; Hiraike H; Hultenby K; Schwend T; Omoto Y; Warner M; Gustafsson J
Article: FEBS LETTERS. 2006;580(3):960-967
Characterization of human thioredoxin-like-1: potential involvement in the cellular response against glucose deprivation.
Jiménez A; Pelto-Huikko M; Gustafsson J-A; Miranda-Vizuete A
Article: STEROIDS. 2006;71(2):91-95
Nongenomic effects of estrogen: why all the uncertainty?
Warner M; Gustafsson J-A
Article: JOURNAL OF PATHOLOGY. 2006;208(3):408-414
Differential expression of oestrogen receptors in human secondary lymphoid tissues
Shim GJ; Gherman D; Kim HJ; Omoto Y; Iwase H; Bouton D; Kis LL; Andersson CT; Warner M; Gustafsson J
Article: AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. 2006;290(2):H823-H829
Dilatory responses to estrogenic compounds in small femoral arteries of male and female estrogen receptor-β knockout mice
Cruz MN; Douglas G; Gustafsson JAK; Poston L; Kublickiene K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006;103(5):1605-1608
Muscle GLUT4 regulation by estrogen receptors ERbeta and ERalpha.
Barros RPA; Machado UF; Warner M; Gustafsson J-A
Article: FERTILITY AND STERILITY. 2006;85(1):63-70
Expression of the proto-oncoprotein breast cancer nuclear receptor auxiliary factor (Brx) is altered in eutopic endometrium of women with endometriosis.
Hearns-Stokes R; Mayers C; Zahn C; Cruess D; Gustafsson J-A; Segars J; Nieman L
Article: NUCLEAR RECEPTOR SIGNALING. 2006;4:e016
Estrogen receptor and aryl hydrocarbon receptor signaling pathways.
Matthews J; Gustafsson J-A
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2005;82(6):1260-1268
Soy-isoflavone-enriched foods and inflammatory biomarkers of cardiovascular disease risk in postmenopausal women:: interactions with genotype and equol production
Hall WL; Vafeiadou K; Hallund J; Bügel S; Koebnick C; Reimann M; Ferrari M; Branca F; Talbot D; Dadd T; Nilsson M; Dahlman-Wright K; Gustafsson J; Minihane AM; Williams CM
Article: NEUROBIOLOGY OF DISEASE. 2005;20(3):961-968
Anti-inflammatory nuclear receptor superfamily in multiple sclerosis patients from Sardinia and Sweden
Liu XA; Steffensen KR; Sanna A; Arru G; Fois ML; Rosati G; Sotgiu S; Link H; Gustafsson J; Huang YM
Article: BREAST CANCER RESEARCH AND TREATMENT. 2005;94(2):145-152
Estrogen receptor beta (ESR2) polymorphisms in familial and sporadic breast cancer
Maguire P; Margolin S; Skoglund J; Sun XF; Gustafsson J; Borresen-Dale AL; Lindblom A
Article: HYPERTENSION. 2005;46(5):1163-1168
Gender-specific alteration of adrenergic responses in small femoral arteries from estrogen receptor-β knockout mice
Luksha L; Poston L; Gustafsson J; Aghajanova L; Kublickiene K
Article: BRITISH JOURNAL OF NUTRITION. 2005;94(5):623-632
The case for strategic international alliances to harness nutritional genomics for public and personal health
Kaput J; Ordovas JM; Ferguson L; van Ommen B; Rodriguez RL; Allen L; Ames BN; Dawson K; German B; Krauss R; Malyj W; Archer MC; Barnes S; Bartholomew A; Birk R; van Bladeren P; Bradford KJ; Brown KH; Caetano R; Castle D; Chadwick R; Clarke S; Clément K; Cooney CA; Corella D; da Cruz IBM; Daniel H; Duster T; Ebbesson SOE; Elliott R; Fairweather-Tait S; Felton J; Fenech M; Finley JW; Fogg-Johnson N; Gill-Garrison R; Gibney MJ; Gillies PJ; Gustafsson J; Hartmann JL; He L; Hwang JK; Jais JP; Jang YS; Joost H; Junien C; Kanter M; Kibbe WA; Koletzko B; Korf BR; Kornman K; Krempin DW; Langin D; Lauren DR; Lee JH; Leveille GA; Lin SJ; Mathers J; Mayne M; McNabb W; Milner JA; Morgan P; Muller M; Nikolsky Y; van der Ouderaa F; Park T; Pensel N; Perez-Jimenez F; Poutanen K; Roberts M; Saris WHM; Schuster G; Shelling AN; Simopoulos AP; Southon S; Tai ES; Towne B; Trayhurn P; Uauy R; Visek WJ; Warden C; Weiss R; Wiencke J; Winkler J; Wolff GL; Xi ZW; Zucker JD
Article: ONCOGENE. 2005;24(44):6605-6616
Estrogen receptors alfa (ERalpha) and beta (ERbeta) differentially regulate proliferation and apoptosis of the normal murine mammary epithelial cell line HC11.
Helguero LA; Faulds MH; Gustafsson J-A; Haldosén L-A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2005;335(1):168-174
Estrogen receptor-alpha regulates SOCS-3 expression in human breast cancer cells.
Matthews J; Almlöf T; Kietz S; Leers J; Gustafsson J-A
Article: JOURNAL OF LIPID RESEARCH. 2005;46(8):1633-1642
LXR deficiency and cholesterol feeding affect the expression and phenobarbital-mediated induction of cytochromes P450 in mouse liver
Gnerre C; Schuster GU; Roth A; Handschin C; Johansson L; Looser R; Parini P; Podvinec M; Robertsson K; Gustafsson J; Meyer UA
Article: BMC IMMUNOLOGY. 2005;6:16
Estren promotes androgen phenotypes in primary lymphoid organs and submandibular glands
Islander U; Hasséus B; Erlandsson MC; Jochems C; Skrtic SM; Lindberg M; Gustafsson J; Ohlsson C; Carlsten H
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2005;332(2):512-517
Selection of DNA aptamers against rat liver X receptors.
Surugiu-Wärnmark I; Wärnmark A; Toresson G; Gustafsson J-A; Bülow L
Article: JOURNAL OF CLINICAL INVESTIGATION. 2005;115(7):1913-1922
Liver X receptors α and β regulate renin expression in vivo
Morello F; de Boer RA; Steffensen KR; Gnecchi M; Chisholm JW; Boomsma F; Anderson LM; Lawn RM; Gustafsson J; Lopez-Ilasaca M; Pratt RE; Dzau VJ
Article: MOLECULAR AND CELLULAR BIOLOGY. 2005;25(13):5317-5328
Aryl hydrocarbon receptor-mediated transcription:: Ligand-dependent recruitment of estrogen receptor α to 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive promoters
Matthews J; Wihlén B; Thomsen J; Gustafsson J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2005;280(24):23024-23031
LXRβ is required for adipocyte growth, glucose homeostasis, and β cell function
Gerin I; Dolinsky VW; Shackman JG; Kennedy RT; Chiang SH; Burant CF; Steffensen KR; Gustafsson J; MacDougald OA
Article: NUCLEIC ACIDS RESEARCH (NAR). 2005;33(11):3561-3569
EID3 is a novel EID family member and an inhibitor of CBP-dependent co-activation
Båvner A; Matthews J; Sanyal S; Gustafsson JA; Treuter E
Article: BIOCHEMISTRY. 2005;44(22):7936-7944
Mouse estrogen receptor β isoforms exhibit differences in ligand selectivity and coactivator recruitment
Zhao CY; Toresson G; Xu L; Koehler KF; Gustafsson J; Dahlman-Wright K
Article: MOLECULAR ENDOCRINOLOGY. 2005;19(6):1412-1417
Steroids and the scientist.
Gustafsson J-A
Article: ENDOCRINOLOGY. 2005;146(6):2519-2530
The liver X receptor-β is essential for maintaining cholesterol homeostasis in the testis
Robertson KM; Schuster GU; Steffensen KR; Hovatta O; Meaney S; Hultenby K; Johansson LC; Svechnikov K; Söder O; Gustafsson J
Article: CLINICAL CANCER RESEARCH. 2005;11(9):3170-3174
Increased estrogen receptor betacx expression during mammary carcinogenesis.
Esslimani-Sahla M; Kramar A; Simony-Lafontaine J; Warner M; Gustafsson J-A; Rochefort H
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2005;330(1):65-74
Absolute mRNA levels and transcriptional regulation of the mouse testis-specific thioredoxins.
Jiménez A; Prieto-Alamo MJ; Fuentes-Almagro CA; Jurado J; Gustafsson J-A; Pueyo C; Miranda-Vizuete A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005;102(12):4608-4612
A previously uncharacterized role for estrogen receptor beta: defeminization of male brain and behavior.
Kudwa AE; Bodo C; Gustafsson J-A; Rissman EF
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005;102(10):3857-3862
Inactivation of liver X receptor β leads to adult-onset motor neuron degeneration in male mice
Andersson S; Gustafsson N; Warner M; Gustafsson J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005;102(10):3593-3598
Delineation of a unique protein-protein interaction site on the surface of the estrogen receptor
Kong EH; Heldring N; Gustafsson J; Treuter E; Hubbard RE; Pike ACW
Article: ENDOCRINOLOGY. 2005;146(3):1214-1225
Hair cycle control by estrogens:: Catagen induction via estrogen receptor (ER)-α is checked by ERβ signaling
Ohnemus U; Uenalan M; Conrad F; Handjiski B; Mecklenburg L; Nakamura M; Inzunza J; Gustafsson J; Paus R
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005;102(8):2814-2819
Early onset of puberty and early ovarian failure in CYP7B1 knockout mice
Omoto Y; Lathe R; Warner M; Gustafsson J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005;102(5):1484-1489
Estrogen receptor α and imprinting of the neonatal mouse ventral prostate by estrogen
Omoto Y; Imamov O; Warner M; Gustafsson J
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2005;230(1-2):17-21
Sex specific expression of progesterone receptor in mouse lower urinary tract.
Savolainen S; Santti R; Streng T; Gustafsson J-A; Härkönen P; Mäkelä S
Article: PHYSIOLOGY AND BEHAVIOR. 2005;84(1):157-163
Lack of functional estrogen receptor beta influences anxiety behavior and serotonin content in female mice.
Imwalle DB; Gustafsson J-A; Rissman EF
Article: NEUROSCIENCE. 2005;130(2):445-456
Differential distribution of estrogen receptor (ER)-α and ER-β in the midbrain raphe nuclei and periaqueductal gray in male mouse:: Predominant role of ER-β in midbrain serotonergic systems
Nomura M; Akama KT; Alves SE; Korach KS; Gustafsson J; Pfaff DW; Ogawa S
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2005;90(1):435-444
Differential regulation of estrogen receptor (ER)α and ERβ in primate mammary gland
Cheng GJ; Li Y; Omoto Y; Wang YL; Berg T; Nord M; Vihko P; Warner M; Piao YS; Gustafsson J
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2004;139(2):210-215
Estren-mediated inhibition of T lymphopoiesis is estrogen receptor-independent whereas its suppression of T cell-mediated inflammation is estrogen receptor-dependent
Islander U; Erlandsson MC; Chavoshi T; Jochems C; Movérare S; Nilsson S; Ohlsson C; Gustafsson J; Carlsten H
Article: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 2004;33(3):609-622
Genome-wide expression profiling;: a panel of mouse tissues discloses novel biological functions of liver X receptors in adrenals
Steffensen KR; Neo SY; Stulnig TM; Vega VB; Rahman SS; Schuster GU; Gustafsson J; Liu ET
Article: MOLECULAR PHARMACOLOGY. 2004;66(6):1440-1452
Overlapping transcriptional programs regulated by the nuclear receptors peroxisome proliferator-activated receptor α, retinoid X receptor, and liver X receptor in mouse liver
Anderson SP; Dunn C; Laughter A; Yoon L; Swanson C; Stulnig TM; Steffensen KR; Chandraratna RAS; Gustafsson J; Corton JC
Article: ENDOCRINOLOGY. 2004;145(12):5525-5531
Estrogen up-regulates hepatic expression of suppressors of cytokine signaling-2 and -3 in vivo and in vitro
Leong GM; Moverare S; Brce J; Doyle N; Sjögren K; Dahlman-Wright K; Gustafsson J; Ho KKY; Ohlsson C; Leung KC
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2004;89(12):6130-6138
Deregulation of estrogen receptor coactivator proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor in human endometrial tumors
Vadlamudi RK; Balasenthil S; Broaddus RR; Gustafsson J; Kumar R
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2004;287(6):E1125-E1131
Difference in skeletal muscle function in males vs. females:: role of estrogen receptor-β
Glenmark B; Nilsson M; Gao H; Gustafsson J; Dahlman-Wright K; Westerblad H
Article: ONCOGENE. 2004;23(54):8826-8833
HES-1 inhibits 17β-estradiol and heregulin-β1-mediated upregulation of E2F-1
Hartman J; Müller P; Foster JS; Wimalasena J; Gustafsson J; Ström A
Article: JOURNAL OF LIPID RESEARCH. 2004;45(11):2052-2062
Tissue-specific autoregulation of the LXRalpha gene facilitates induction of apoE in mouse adipose tissue.
Ulven SM; Dalen KT; Gustafsson J-A; Nebb HI
Article: CARCINOGENESIS. 2004;25(11):2067-2073
Identification of a functional variant of estrogen receptor beta in an African population
Zhao CY; Xu L; Otsuki M; Toresson G; Koehler K; Pan-Hammarström Q; Hammarström L; Nilsson S; Gustafsson J; Dahlman-Wright K
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2004;20(9):2345-2354
Estrogen receptor beta is expressed in human embryonic brain cells and is regulated by 17β-estradiol
Fried G; Andersson E; Csöregh L; Enmark E; Gustafsson J; Aanesen A; Österlund C
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2004;279(44):46204-46212
Mimetics of caloric restriction include agonists of lipid-activated nuclear receptors
Corton JC; Apte U; Anderson SP; Limaye P; Yoon L; Latendresse J; Dunn C; Everitt JI; Voss KA; Swanson C; Kimbrough C; Wong JS; Gill SS; Chandraratna RAS; Kwak MK; Kensler TW; Stulnig TM; Steffensen KR; Gustafsson J; Mehendale HM
Article: ENDOCRINOLOGY. 2004;145(10):4500-4506
Estrogen receptor beta modulates estradiol induction of progestin receptor immunoreactivity in male, but not in female, mouse medial preoptic area.
Kudwa AE; Gustafsson J-A; Rissman EF
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(39):14234-14239
Characterization of the ERβ^-/- mouse heart
Förster C; Kietz S; Hultenby K; Warner M; Gustafsson JA
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2004;279(37):38721-38729
An alternative splicing variant of the selenoprotein thioredoxin reductase is a modulator of estrogen signaling
Damdimopoulos AE; Miranda-Vizuete A; Treuter E; Gustafsson J; Spyrou G
Article: CLINICAL CANCER RESEARCH. 2004;10(17):5769-5776
Estrogen receptor beta (ER beta) level but not its ER beta cx variant helps to predict tamoxifen resistance in breast cancer.
Esslimani-Sahla M; Simony-Lafontaine J; Kramar A; Lavaill R; Mollevi C; Warner M; Gustafsson J-A; Rochefort H
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(34):12628-12633
Aromatase-deficient mice spontaneously develop a lymphoproliferative autoimmune disease resembling Sjogren's syndrome
Shim GJ; Warner M; Kim HJ; Andersson S; Liu LN; Ekman J; Imamov O; Jones ME; Simpson ER; Gustafsson J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2004;279(33):34971-34982
Spermatocyte/spermatid-specific thioredoxin-3, a novel Golgi apparatus-associated thioredoxin, is a specific marker of aberrant spermatogenesis.
Jiménez A; Zu W; Rawe VY; Pelto-Huikko M; Flickinger CJ; Sutovsky P; Gustafsson J-A; Oko R; Miranda-Vizuete A
Article: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 2004;33(1):35-50
The expression of oestrogen receptor (ER)-β and its variants, but not ERα, in adult human mammary fibroblasts
Palmieri C; Saji S; Sakaguchi H; Cheng G; Sunters A; O'Hare MJ; Warner M; Gustafsson J; Coombes RC; Lam EWF
Article: GENES, BRAIN AND BEHAVIOR. 2004;3(4):189-195
Oxytocin and estrogen receptor α and β knockout mice provide
Kavaliers M; Ågmo A; Choleris E; Gustafsson J; Korach KS; Muglia LJ; Pfaff DW; Ogawa S
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2004;320(1):76-82
The Ah receptor inhibits estrogen-induced estrogen receptor β in breast cancer
Kietz S; Thomsen JS; Matthews J; Pettersson K; Ström A; Gustafsson J
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2004;221(1-2):97-104
Estrogen and progesterone receptors in ovarian epithelial tumors
Lindgren PR; Cajander S; Bäckström T; Gustafsson J; Mäkelä S; Olofsson JI
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(25):9375-9380
Estrogen receptor β regulates epithelial cellular differentiation in the mouse ventral prostate
Imamov O; Morani A; Shim GJ; Omoto Y; Thulin-Andersson C; Warner M; Gustafsson JA
Article: AMERICAN JOURNAL OF PATHOLOGY. 2004;164(6):1915-1924
Estrogen receptor-1 (Esr1) and -2 (Esr2) regulate the severity of clinical experimental allergic encephalomyelitis in male mice.
Polanczyk M; Yellayi S; Zamora A; Subramanian S; Tovey M; Vandenbark AA; Offner H; Zachary JF; Fillmore PD; Blankenhorn EP; Gustafsson J-A; Teuscher C
Article: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 2004;32(3):879-892
Gene expression profiling identifies liver X receptor alpha as an estrogen-regulated gene in mouse adipose tissue
Lundholm L; Movérare S; Steffensen KR; Nilsson M; Otsuki M; Ohlsson C; Gustafsson J; Dahlman-Wright K
Article: PROTEIN EXPRESSION AND PURIFICATION. 2004;35(2):190-198
Purification of functional full-length liver X receptor β produced in Escherichia coli
Toresson G; Schuster GU; Steffensen KR; Bengtsson M; Ljunggren J; Dahlman-Wright K; Gustafsson J
Article: CARCINOGENESIS. 2004;25(5):741-748
Prepubertal estradiol and genistein exposures up-regulate BRCA1 mRNA and reduce mammary tumorigenesis
Cabanes A; Wang M; Olivo S; DeAssis S; Gustafsson J; Khan G; Hilakivi-Clarke L
Article: BIOMARKERS. 2004;9(3):243-257
DNA adduct formation of 14 heterocyclic aromatic amines in mouse tissue after oral administration and characterization of the DNA adduct formed by 2-amino-9H-pyrido[2,3-b]indole (AαC), analysed by ³²P-HPLC
Baranczewski P; Gustafsson J; Möller L
Article: CLINICAL CANCER RESEARCH. 2004;10(7):2421-2428
The expression of ERβcx in human breast cancer and the relationship to endocrine therapy and survival
Palmieri C; Lam EWF; Mansi J; MacDonald C; Shousha S; Madden P; Omoto Y; Sunters A; Warner M; Gustafsson J; Coombes RC
Article: MOLECULAR AND CELLULAR BIOLOGY. 2004;24(8):3445-3459
Identification of tamoxifen-induced coregulator interaction surfaces within the ligand-binding domain of estrogen receptors
Heldring N; Nilsson M; Buehrer B; Treuter E; Gustafsson J
Article: MOLECULAR AND CELLULAR BIOLOGY. 2004;24(8):3430-3444
Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor γ expression
Seo JB; Moon HM; Kim WS; Lee YS; Jeong HW; Yoo EJ; Ham JY; Kang HJ; Park MG; Steffensen KR; Stulnig TM; Gustafsson J; Dai Park S; Kim JB
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(11):3739-3746
Estrogen receptors ER alpha and ER beta in proliferation in the rodent mammary gland.
Cheng G; Weihua Z; Warner M; Gustafsson J-A
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2004;279(10):9255-9263
The focal adhesion protein vinexin alpha regulates the phosphorylation and activity of estrogen receptor alpha.
Tujague M; Thomsen JS; Mizuki K; Sadek CM; Gustafsson J-A
Article: GENE. 2004;327(2):233-238
The human RAP250 gene:: genomic structure and promoter analysis
Antonson P; Al-Beidh F; Matthews J; Gustafsson J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(6):1720-1724
Autoimmune glomerulonephritis with spontaneous formation of splenic germinal centers in mice lacking the estrogen receptor alpha gene.
Shim G-J; Kis LL; Warner M; Gustafsson J-A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(6):1566-1571
Estrogen receptor β inhibits 17β-estradiol-stimulated proliferation of the breast cancer cell line T47D
Ström A; Hartman J; Foster JS; Kietz S; Wimalasena J; Gustafsson JA
Article: MOLECULAR ENDOCRINOLOGY. 2004;18(2):412-421
Estrogen receptor functional activity changes during differentiation of mammary epithelial cells.
Faulds MH; Olsen H; Helguero LA; Gustafsson J-A; Haldosén L-A
Article: MOLECULAR ENDOCRINOLOGY. 2004;18(2):312-325
Deoxyribonucleic acid response element-dependent regulation of transcription by orphan nuclear receptor estrogen receptor-related receptor γ
Sanyal S; Matthews J; Bouton D; Kim HJ; Choi HS; Treuter E; Gustafsson J
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2004;89(2):557-562
Prevalence and clinical associations of 10 defined autoantibodies in autoimmune polyendocrine syndrome type I
Söderbergh A; Myhre AG; Ekwall O; Gebre-Medhin G; Hedstrand H; Landgren E; Miettinen A; Eskelin P; Halonen M; Tuomi T; Gustafsson J; Husebye ES; Perheentupa J; Gylling M; Manns MP; Rorsman F; Kämpe O; Nilsson T
Article: GYNECOLOGIC ONCOLOGY. 2004;92(1):31-39
ERBB2 amplification is superior to protein expression status in predicting patient outcome in serous ovarian carcinoma.
Lassus H; Leminen A; Vayrynen A; Cheng G; Gustafsson J-A; Isola J; Butzow R
Article: JOURNAL OF ENDOCRINOLOGY. 2004;180(1):55-62
Estrogen receptor-beta is the predominant estrogen receptor subtype in human oral epithelium and salivary glands.
Välimaa H; Savolainen S; Soukka T; Silvoniemi P; Mäkelä S; Kujari H; Gustafsson J-A; Laine M
Article: MOLECULAR PHARMACOLOGY. 2004;65(1):165-171
HES-1, a novel target gene for the aryl hydrocarbon receptor
Thomsen JS; Kietz S; Ström A; Gustafsson J
Article: MOLECULAR PSYCHIATRY. 2004;9(1):28-34
Association of estrogen receptor β gene polymorphisms with bulimic disease in women
Nilsson M; Naessén S; Dahlman I; Hirschberg AL; Gustafsson JA; Dahlman-Wright K
Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2004;19(1):72-77
Estrogen receptor-β inhibits skeletal growth and has the capacity to mediate growth plate fusion in female mice
Chagin AS; Lindberg MK; Andersson N; Moverare S; Gustafsson J; Sävendahl L; Ohlsson C
Article: GENOME BIOLOGY. 2004;5(9):R66
Discovery of estrogen receptor a target genes and response elements in breast tumor cells -: art. no. R66
Lin CY; Ström A; Vega VB; Kong SL; Yeo AL; Thomsen JS; Chan WC; Doray B; Bangarusamy DK; Ramasamy A; Vergara LA; Tang SS; Chong A; Bajic VB; Miller LD; Gustafsson J; Liu ET
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2003;312(3):716-724
Glucocorticoid response and promoter occupancy of the mouse LXRα gene
Steffensen KR; Holter E; Alikhani N; Eskild W; Gustafsson J
Article: HORMONES AND BEHAVIOR. 2003;44(5):427-434
Lack of functional estrogen receptor beta gene disrupts pubertal male sexual behavior.
Temple JL; Scordalakes EM; Bodo C; Gustafsson JA; Rissman EF
Article: MOLECULAR PHARMACOLOGY. 2003;64(6):1428-1433
Estren is a selective estrogen receptor modulator with transcriptional activity
Movérare S; Dahllund J; Andersson N; Islander U; Carlsten H; Gustafsson JA; Nilsson S; Ohlsson C
Article: MOLECULAR AND CELLULAR BIOLOGY. 2003;23(23):8542-8552
Regulation of postnatal lung development and homeostasis by estrogen receptor β
Patrone C; Cassel TN; Pettersson K; Piao YS; Cheng GJ; Ciana P; Maggi A; Warner M; Gustafsson J; Nord M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(48):48283-48291
Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor alpha.
Dalen KT; Ulven SM; Bamberg K; Gustafsson J-A; Nebb HI
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2003;100(23):13573-13578
Differential effects on bone of estrogen receptor α and androgen receptor activation in orchidectomized adult male mice
Movérare S; Venken K; Eriksson AL; Andersson N; Skrtic S; Wergedal I; Mohan S; Salmon P; Bouillon R; Gustafsson J; Vanderschueren D; Ohlsson C
Article: ONCOGENE. 2003;22(48):7600-7606
Expression of estrogen receptor β isoforms in normal breast epithelial cells and breast cancer:: regulation by methylation
Zhao CY; Lam EWF; Sunters A; Enmark E; De Bella MT; Coombes RC; Gustafsson J; Dahlman-Wright K
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2003;310(2):589-593
Gene expression profiling in adipose tissue indicates different transcriptional mechanisms of liver X receptors α and β, respectively
Steffensen KR; Nilsson M; Schuster GU; Stulnig TM; Dahlman-Wright K; Gustafsson J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(40):38821-38828
The three-dimensional structure of the liver X receptor β reveals a flexible ligand-binding pocket that can accommodate fundamentally different ligands
Färnegårdh M; Bonn T; Sun S; Ljunggren J; Ahola H; Wilhelmsson A; Gustafsson J; Carlquist M
Article: CANCER RESEARCH. 2003;63(19):6258-6264
Glycodelin in ovarian serous carcinoma: association with differentiation and survival.
Mandelin E; Lassus H; Seppälä M; Leminen A; Gustafsson J-A; Cheng G; Bützow R; Koistinen R
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2003;100(19):11019-11022
Genetic contributions to generalized arousal of brain and behavior
Garey J; Goodwillie A; Frohlich J; Morgan M; Gustafsson JA; Smithies O; Korach KS; Ogawa S; Pfaff DW
Article: IMMUNOLOGY. 2003;110(1):149-157
Influence of oestrogen receptor alpha and beta on the immune system in aged female mice.
Islander U; Erlandsson MC; Hasséus B; Jonsson CA; Ohlsson C; Gustafsson J-A; Dahlgren U; Carlsten H
Article: JOURNAL OF UROLOGY. 2003;170(3):1013-1016
Estrogen receptor subtypes and afferent signaling in the bladder.
Schröder A; Pandita RK; Hedlund P; Warner M; Gustafsson J-A; Andersson K-E
Article: MOLECULAR ENDOCRINOLOGY. 2003;17(9):1844-1855
Specific regulation of lipocalin-type prostaglandin D synthase in mouse heart by estrogen receptor β
Otsuki M; Gao H; Dahlman-Wright K; Ohlsson C; Eguchi N; Urade Y; Gustafsson J
Article: ENDOCRINOLOGY. 2003;144(8):3541-3546
Human estrogen receptor β 548 is not a common variant in three distinct populations
Xu L; Pan-Hammarström Q; Försti A; Hemminki K; Hammarström L; Labuda D; Gustafsson J; Dahlman-Wright K
Article: FEBS LETTERS. 2003;546(1):17-24
Update on estrogen signaling
Zhang WH; Andersson S; Cheng GJ; Simpson ER; Warner M; Gustafsson J
Article: BIOCHEMICAL JOURNAL. 2003;373(Pt 1):211-220
Cytosolic glucocorticoid receptor interaction with nuclear factor-κB proteins in rat liver cells
Widén C; Gustafsson J; Wikström AC
Article: NUCLEIC ACIDS RESEARCH (NAR). 2003;31(13):3605-3607
Dragon ERE Finder version 2:: a tool for accurate detection and analysis of estrogen response elements in vertebrate genomes
Bajic VB; Tan SL; Chong A; Tang S; Ström A; Gustafsson J; Lin CY; Liu ET
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(25):22748-22754
The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain -: RU-486 induces a transconformation that leads to active antagonism
Kauppi B; Jakob C; Färnegårdh M; Yang J; Ahola H; Alarcon M; Calles K; Engström O; Harlan J; Muchmore S; Ramqvist AK; Thorell S; Öhman L; Greer J; Gustafsson J; Carlstedt-Duke J; Carlquist M
Article: BREAST CANCER RESEARCH AND TREATMENT. 2003;79(3):409-413
Polymorphisms in the estrogen receptor beta gene and risk of breast cancer:: no association
Försti A; Zhao CY; Israelsson E; Dahlman-Wright K; Gustafsson J; Hemminki K
Article: MOLECULAR AND CELLULAR BIOLOGY. 2003;23(12):4187-4198
Regulation of subnuclear localization is associated with a mechanism for nuclear receptor corepression by RIP140
Tazawa H; Osman W; Shoji Y; Treuter E; Gustafsson J; Zilliacus J
Article: AUTONOMIC NEUROSCIENCE: BASIC AND CLINICAL. 2003;105(2):90-100
Estrogen receptor expression in lumbosacral dorsal root ganglion cells innervating the female rat urinary bladder.
Bennett HL; Gustafsson JA; Keast JR
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2003;100(11):6694-6699
Disruption of the estrogen receptor β gene in mice causes myeloproliferative disease resembling chronic myeloid leukemia with lymphoid blast crisis
Shim GJ; Wang L; Andersson S; Nagy N; Kis LL; Zhang QH; Mäkelä S; Warner M; Gustafsson J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2003;100(10):6192-6197
An estrogen-dependent four-gene micronet regulating social recognition:: A study with oxytocin and estrogen receptor-α and -β knockout mice
Choleris E; Gustafsson J; Korach KS; Muglia LJ; Pfaff DW; Ogawa S
Article: GENE EXPRESSION PATTERNS. 2003;3(2):203-211
TACC3 expression is tightly regulated during early differentiation
Sadek CM; Pelto-Huikko M; Tujague M; Steffensen KR; Wennerholm M; Gustafsson J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(15):13133-13142
Characterization of human thioredoxin-like 2 -: A novel microtubule-binding thioredoxin expressed predominantly in the cilia of lung airway epithelium and spermatid manchette and axoneme
Sadek CM; Jiménez A; Damdimopoulos AE; Kieselbach T; Nord M; Gustafsson JA; Spyrou I; Davis EC; Oko R; van der Hoorn FA; Miranda-Vizuete A
Article: JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY. 2003;51(4):455-469
Aint/Tacc3 is highly expressed in proliferating mouse tissues during development, spermatogenesis, and oogenesis.
Aitola M; Sadek CM; Gustafsson J-A; Pelto-Huikko M
Article: JOURNAL OF NEUROSCIENCE RESEARCH. 2003;71(6):802-810
Estrogen receptor-alpha is required for estrogen-induced mu-opioid receptor internalization.
Micevych PE; Rissman EF; Gustafsson J-A; Sinchak K
Article: MOLECULAR ENDOCRINOLOGY. 2003;17(2):172-182
On the role of liver X receptors in lipid accumulation in adipocytes.
Juvet LK; Andresen SM; Schuster GU; Dalen KT; Tobin KAR; Hollung K; Haugen F; Jacinto S; Ulven SM; Bamberg K; Gustafsson J-A; Nebb HI
Article: MOLECULAR AND CELLULAR BIOLOGY. 2003;23(4):1260-1268
Inactivation of the nuclear receptor coactivator RAP250 in mice results in placental vascular dysfunction
Antonson P; Schuster GU; Wang L; Rozell B; Holter E; Flodby P; Treuter E; Holmgren L; Gustafsson J
Article: MOLECULAR ENDOCRINOLOGY. 2003;17(2):203-208
Estrogen receptor (ER)-β reduces ERα-regulated gene transcription, supporting a "Ying Yang" relationship between ERα and ERβ in mice
Lindberg MK; Movérare S; Skrtic S; Gao H; Dahlman-Wright K; Gustafsson J; Ohlsson C
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2003;100(2):703-708
Estrogen receptor (ER)β knockout mice reveal a role for ERβ in migration of cortical neurons in the developing brain
Wang L; Andersson S; Warner M; Gustafsson J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(2):1059-1066
ERdJ5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress
Cunnea PM; Miranda-Vizuete A; Bertoli G; Simmen T; Damdimopoulos AE; Hermann S; Leinonen S; Huikko MP; Gustafsson J; Sitia R; Spyrou G
Article: NUCLEAR RECEPTOR SIGNALING. 2003;1:e003-nrs.01003
Cardiovascular roles of estrogen receptors: insights gained from knockout models.
Otsuki M; Dahlman-Wright K; Gustafsson J-A
Article: ENDOCRINOLOGY. 2003;144(1):230-239
Estrogen increases locomotor activity in mice through estrogen receptor α:: Specificity for the type of activity
Ogawa S; Chan J; Gustafsson J; Korach KS; Pfaff DW
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(51):49761-49766
Glucocorticoid signaling is perturbed by the atypical orphan receptor and corepressor SHP
Borgius LJ; Steffensen KR; Gustafsson J; Treuter E
Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2002;17(12):2183-2195
Identification of estrogen-regulated genes of potential importance for the regulation of trabecular bone mineral density
Lindberg MK; Movérare S; Eriksson AL; Skrtic S; Gao H; Dahlman-Wright K; Gustafsson J; Ohlsson C
Article: MOLECULAR PHARMACOLOGY. 2002;62(6):1299-1305
Novel roles of liver X receptors exposed by gene expression profiling in liver and adipose tissue
Stulnig TM; Steffensen KR; Gao H; Reimers M; Dahlman-Wright K; Schuster GU; Gustafsson J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2002;99(24):15578-15583
Involvement of estrogen receptor β in terminal differentiation of mammary gland epithelium
Förster C; Mäkela S; Wärri A; Kietz S; Becker D; Hultenby K; Warner M; Gustafsson J
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2002;119(5):1053-1058
Estrogen receptor alpha, but not estrogen receptor beta, is involved in the regulation of the hair follicle cycling as well as the thickness of epidermis in male mice.
Movérare S; Lindberg MK; Faergemann J; Gustafsson J-A; Ohlsson C
Article: MOLECULAR ENDOCRINOLOGY. 2002;16(11):2571-2581
Transcriptional synergism on the pS2 gene promoter between a p160 coactivator and estrogen receptor-alpha depends on the coactivator subtype, the type of estrogen response element, and the promoter context.
Barkhem T; Haldosén L-A; Gustafsson J-A; Nilsson S
Article: ENDOCRINOLOGY. 2002;143(11):4196-4202
Estrogen receptor-alpha (ERalpha), but not ERbeta, modulates estrogen stimulation of the ERalpha-truncated variant, TERP-1.
Schreihofer DA; Rowe DF; Rissman EF; Scordalakes EM; Gustafsson J J-Å; Shupnik MA
Article: FEBS LETTERS. 2002;530(1-3):79-84
Human spermatid-specific thioredoxin-1 (Sptrx-1) is a two-domain protein with oxidizing activity
Jiménez A; Johansson C; Ljung J; Sagemark J; Berndt KD; Ren B; Tibbelin G; Ladenstein R; Kieselbach T; Holmgren A; Gustafsson J; Miranda-Vizuete A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2002;99(21):13589-13594
An endocrine pathway in the prostate, ERbeta, AR, 5alpha-androstane-3beta,17beta-diol, and CYP7B1, regulates prostate growth.
Weihua Z; Lathe R; Warner M; Gustafsson J-A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2002;99(21):13878-13883
Liver X receptors in the central nervous system:: From lipid homeostasis to neuronal degeneration
Wang L; Schuster GU; Hultenby K; Zhang QH; Andersson S; Gustafsson J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(36):33249-33257
Human mitochondrial thioredoxin -: Involvement in mitochondrial membrane potential and cell death
Damdimopoulos AE; Miranda-Vizuete A; Pelto-Huikko M; Gustafsson J; Spyrou G
Article: CANCER RESEARCH. 2002;62(17):4849-4853
Expression of estrogen receptor (ER) βcx protein in ERα-positive breast cancer:: Specific correlation with progesterone receptor
Saji S; Omoto Y; Shimizu C; Warner M; Hayashi Y; Horiguchi S; Watanabe T; Hayashi S; Gustafsson J; Toi M
Article: CIRCULATION. 2002;106(9):1147-1153
Accumulation of foam cells in liver X receptor-deficient mice
Schuster GU; Parini P; Wang L; Alberti S; Steffensen KR; Hansson GK; Angelin B; Gustafsson J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(32):28376-28379
The anti-estrogenic effect of all-trans-retinoic acid on the breast cancer cell line MCF-7 is dependent on HES-1 expression
Müller P; Kietz S; Gustafsson J; Ström A
Article: MOLECULAR HUMAN REPRODUCTION. 2002;8(8):710-718
Cloning, expression and characterization of mouse spermatid specific thioredoxin-1 gene and protein.
Jiménez A; Oko R; Gustafsson J-A; Spyrou G; Pelto-Huikko M; Miranda-Vizuete A
Article: JOURNAL OF ENDOCRINOLOGY. 2002;174(2):167-178
Estrogen receptor specificity for the effects of estrogen in ovariectomized mice
Lindberg MK; Weihua Z; Andersson N; Movérare S; Gao H; Vidal O; Erlandsson M; Windahl S; Andersson G; Lubahn DB; Carlsten H; Dahlman-Wright K; Gustafsson J; Ohlsson C
Article: DIABETES. 2002;51(8):2426-2433
Liver X receptors downregulate 11β-hydroxysteroid dehydrogenase type 1 expression and activity
Stulnig TM; Oppermann U; Steffensen KR; Schuster GU; Gustafsson J
Article: BIOLOGY OF REPRODUCTION. 2002;67(2):616-623
Involvement of androgen receptor in 17β-estradiol-induced cell proliferation in rat uterus
Zhang WH; Ekman J; Almkvist Å; Saji S; Wang L; Warner M; Gustafsson J
Article: MOLECULAR ENDOCRINOLOGY. 2002;16(7):1598-1611
Possible involvement of truncated signal transducer and activator of transcription-5 in the GH pattern-dependent regulation of CYP2C12 gene expression in rat liver
Helander H; Gustafsson J; Mode A
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(24):21862-21868
Interaction of transcriptional intermediary factor 2 nuclear receptor box peptides with the coactivator binding site of estrogen receptor α
Wärnmark A; Treuter E; Gustafsson J; Hubbard RE; Brzozowski AM; Pike ACW
Article: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. 2002;128(6):319-324
Estrogen receptor beta is expressed in human stomach adenocarcinoma.
Matsuyama S; Ohkura Y; Eguchi H; Kobayashi Y; Akagi K; Uchida K; Nakachi K; Gustafsson J-A; Hayashi S-I
Article: MOLECULAR PHARMACOLOGY. 2002;61(6):1273-1283
pS2 gene expression in HepG2 cells:: Complex regulation through crosstalk between the estrogen receptor α, an estrogen-responsive element, and the activator protein 1 response element
Barkhem T; Haldosén LA; Gustafsson J; Nilsson S
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2002;293(5):1333-1340
Different regulation of the LXRα promoter activity by isoforms of CCAAT/enhancer-binding proteins
Steffensen KR; Schuster GU; Parini P; Holter E; Sadek CM; Cassel T; Eskild W; Gustafsson J
Article: EMBO REPORTS. 2002;3(5):478-484
A transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHP
Båvner A; Johansson L; Toresson G; Gustafsson J; Treuter E
Article: HORMONES AND BEHAVIOR. 2002;41(3):288-296
Genotype/age interactions on aggressive behavior in gonadally intact estrogen receptor β knockout (βERKO) male mice
Nomura M; Durbak L; Chan J; Smithies O; Gustafsson J; Korach KS; Pfaff DW; Ogawa S
Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2002;17(4):555-562
Two different pathways for the maintenance of trabecular bone in adult male mice.
Lindberg MK; Movérare S; Skrtic S; Alatalo S; Halleen J; Mohan S; Gustafsson JA; Ohlsson C
Article: BIOLOGY OF REPRODUCTION. 2002;66(4):1054-1060
Expression of estrogen receptors alpha and beta in the baboon fetal ovary.
Pepe GJ; Billiar RB; Leavitt MG; Zachos NC; Gustafsson JA; Albrecht ED
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(12):10691-10697
Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis.
Tobin KAR; Ulven SM; Schuster GU; Steineger HH; Andresen SM; Gustafsson J-A; Nebb HI
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2002;99(6):3996-4001
Disruption of estrogen receptor beta gene impairs spatial learning in female mice.
Rissman EF; Heck AL; Leonard JE; Shupnik MA; Gustafsson J-A
Article: ENDOCRINE-RELATED CANCER. 2002;9(1):1-13
Estrogen receptor beta in breast cancer
Palmieri C; Cheng GJ; Saji S; Zelada-Hedman M; Wärri A; Weihua Z; Van Noorden S; Wahlstrom T; Coombes RC; Warner M; Gustafsson J
Article: MOLECULAR ENDOCRINOLOGY. 2002;16(3):515-528
Inhibition of androgen receptor (AR) function by the reproductive orphan nuclear receptor DAX-1
Holter E; Kotaja N; Mäkela S; Strauss L; Kietz S; Jänne OA; Gustafsson J; Palvimo JJ; Treuter E
Article: EUROPEAN JOURNAL OF CANCER. 2002;38(3):380-386
Evaluation of oestrogen receptor β wild-type and variant protein expression, and relationship with clinicopathological factors in breast cancers
Omoto Y; Kobayashi S; Inoue S; Ogawa S; Toyama T; Yamashita H; Muramatsu M; Gustafsson J; Iwase H
Article: SCIENCE. 2002;295(5554):505-508
Abnormal vascular function and hypertension in mice deficient in estrogen receptor β
Zhu Y; Bian Z; Lu P; Karas RH; Bao L; Cox D; Hodgin J; Shaul PW; Thorén P; Smithies O; Gustafsson J; Mendelsohn ME
Article: BIOLOGY OF REPRODUCTION. 2002;66(1):77-84
A role for the androgen receptor in follicular atresia of estrogen receptor beta knockout mouse ovary
Cheng GJ; Zhang WH; Mäkinen S; Saji S; Warner M; Gustafsson J; Hovatta O
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2001;289(5):1262-1267
Members of the nuclear factor 1 family reduce the transcriptional potential of the nuclear receptor LXRα promoter
Steffensen KR; Holter E; Tobin KAR; Leclerc S; Gustafsson J; Guérin SL; Eskild W
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2001;98(26):15197-15202
Estrogen receptors and proliferation markers in primary and recurrent breast cancer
Jensen EV; Cheng GJ; Palmieri C; Saji S; Mäkelä S; Van Noorden S; Wahlström T; Warner M; Coombes RC; Gustafsson J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(49):45939-45944
The N-terminal regions of estrogen receptor α and β are unstructured in vitro and show different TBP binding properties
Wärnmark A; Wikström A; Wright APH; Gustafsson J; Härd T
Article: JOURNAL OF ENDOCRINOLOGY. 2001;171(3):425-433
Estrogen receptor α, but not estrogen receptor β, is involved in the regulation of the OPG/RANKL (osteoprotegerin/receptor activator of NF-κB ligand) ratio and serum interleukin-6 in male mice
Lindberg MK; Erlandsson M; Alatalo SL; Windahl S; Andersson C; Halleen JM; Carlsten H; Gustafsson J; Ohlsson C
Article: JOURNAL OF ENDOCRINOLOGY. 2001;171(3):417-423
Stimulation of vascular protein synthesis by activation of oestrogen receptor β
Liang M; Ekblad E; Gustafsson J; Nilsson B
Article: GENES TO CELLS. 2001;6(12):1077-1090
Sptrx-2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP-kinase domains is expressed in human testis germ cells
Sadek CM; Damdimopoulos AE; Pelto-Huikko M; Gustafsson J; Spyrou G; Miranda-Vizuete A
Article: JOURNAL OF ENDOCRINOLOGY. 2001;171(2):229-236
Estrogen receptor specificity in the regulation of the skeleton in female mice.
Lindberg MK; Alatalo SL; Halleen JM; Mohan S; Gustafsson JA; Ohlsson C
Article: MOLECULAR ENDOCRINOLOGY. 2001;15(11):1929-1940
Cross-talk between ERs and signal transducer and activator of transcription 5 is E2 dependent and involves two functionally separate mechanisms
Faulds MH; Pettersson K; Gustafsson J; Haldosén LA
Article: JAPANESE JOURNAL OF CANCER RESEARCH. 2001;92(10):1057-1061
Clinicopathological characteristics of estrogen receptor-beta-positive human breast cancers.
Miyoshi Y; Taguchi T; Gustafsson JA; Noguchi S
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2001;9(10):802-804
Investigations of a CA repeat in the oestrogen receptor β gene in patients with Alzheimer's disease
Forsell C; Enmark E; Axelman K; Blomberg M; Wahlund LO; Gustafsson JA; Lannfelt L
Article: CIRCULATION RESEARCH. 2001;89(6):534-539
Effects of estrogen on the vascular injury response in estrogen receptor alpha, beta (double) knockout mice.
Karas RH; Schulten H; Pare G; Aronovitz MJ; Ohlsson C; Gustafsson JA; Mendelsohn ME
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2001;109(9):943-947
Diethylnitrosamine causes pituitary damage, disturbs hormone levels, and reduces sexual dimorphism of certain liver functions in the rat.
Liao DJ; Blanck A; Eneroth P; Gustafsson JA; Hällström IP
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(34):31567-31574
Characterization of Sptrx, a novel member of the thioredoxin family specifically expressed in human spermatozoa
Miranda-Vizuete A; Ljung J; Damdimopoulos AE; Gustafsson J; Oko R; Pelto-Huikko M; Spyrou G
Article: JOURNAL OF UROLOGY. 2001;166(2):674-677
Co-localization of androgen receptor with estrogen receptor beta in the lower urinary tract of the male rat.
Salmi S; Santti R; Gustafsson JA; Mäkelä S
Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2001;16(8):1388-1398
Female estrogen receptor β-/- mice are partially protected against age-related trabecular bone loss
Windahl SH; Hollberg K; Vidal O; Gustafsson J; Ohlsson C; Andersson G
Article: CANCER RESEARCH. 2001;61(14):5331-5335
Frequent loss of estrogen receptor-beta expression in prostate cancer.
Horvath LG; Henshall SM; Lee CS; Head DR; Quinn DI; Makela S; Delprado W; Golovsky D; Brenner PC; O'Neill G; Kooner R; Stricker PD; Grygiel JJ; Gustafsson JA; Sutherland RL
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2001;285(2):340-347
Expression, function, and clinical implications of the estrogen receptor β in human lung cancers
Omoto Y; Kobayashi Y; Nishida K; Tsuchiya E; Eguchi H; Nakagawa K; Ishikawa Y; Yamori T; Iwase H; Fujii Y; Warner M; Gustafsson J; Hayashi S
Article: ENDOCRINOLOGY. 2001;142(7):3177-3186
Quantitative analysis of estrogen receptor proteins in rat mammary gland
Saji S; Sakaguchi H; Andersson S; Warner M; Gustafsson J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(26):23397-23404
Differential recruitment of the mammalian mediator subunit TRAP220 by estrogen receptors ERα and ERβ
Wärnmark A; Almlöf T; Leers J; Gustafsson J; Treuter E
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(26):23937-23944
Neurosteroid hydroxylase CYP7B -: Vivid reporter activity in dentate gyrus of gene-targeted mice and abolition of a widespread pathway of steroid and oxysterol hydroxylation
Rose K; Allan A; Gauldie S; Stapleton G; Dobbie L; Dott X; Martin C; Wang L; Hedlund E; Seckl JR; Gustafsson J; Lathe R
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(24):21410-21416
Acyl-CoA esters antagonize the effects of ligands on peroxisome proliferator-activated receptor alpha conformation, DNA binding, and interaction with Co-factors.
Elholm M; Dam I; Jorgensen C; Krogsdam AM; Holst D; Kratchmarova I; Gottlicher M; Gustafsson JA; Berge R; Flatmark T; Knudsen J; Mandrup S; Kristiansen K
Article: MOLECULAR HUMAN REPRODUCTION. 2001;7(6):497-503
Localization of oestrogen receptors alpha and beta in human testis
Mäkinen S; Mäkelä S; Zhang WH; Warner M; Rosenlund B; Salmi S; Hovatta O; Gustafsson J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2001;98(11):6330-6335
A role for estrogen receptor ß in the regulation of growth of the ventral prostate
Zhang WH; Mäkelä S; Andersson LC; Salmi S; Saji S; Webster JI; Jensen EV; Nilsson S; Warner M; Gustafsson JA
Article: IMMUNOLOGY. 2001;103(1):17-25
Role of oestrogen receptors alpha and beta in immune organ development and in oestrogen-mediated effects on thymus.
Erlandsson MC; Ohlsson C; Gustafsson JA; Carlsten H
Article: JOURNAL OF ENDOCRINOLOGY. 2001;169(2):241-247
Immunocytochemical demonstration of oestrogen receptor β in blood vessels of the female rat
Andersson C; Lydrup ML; Fernö M; Idvall I; Gustafsson J; Nilsson BO
Article: MOLECULAR AND CELLULAR BIOLOGY. 2001;21(9):3266-3279
Expression level-dependent contribution of glucocorticoid receptor domains for functional interaction with STAT5
Doppler W; Windegger M; Soratroi C; Tomasi J; Lechner J; Rusconi S; Cato ACB; Almlof T; Liden J; Okret S; Gustafsson J; Richard-Foy H; Starr DB; Klocker H; Edwards D; Geymayer S
Article: MOLECULAR ENDOCRINOLOGY. 2001;15(4):501-511
Regulation of glucocorticoid receptor activity by 14-3-3-dependent intracellular relocalization of the corepressor RIP140
Zilliacus J; Holter E; Wakui H; Tazawa H; Treuter E; Gustafsson J
Article: CANCER RESEARCH. 2001;61(6):2537-2541
Decreased expression of estrogen receptor beta protein in proliferative preinvasive mammary tumors.
Roger P; Sahla ME; Mäkelä S; Gustafsson JA; Baldet P; Rochefort H
Article: ENDOCRINOLOGY. 2001;142(3):1156-1166
4-hydroxytamoxifen trans-represses nuclear factor-kappa B activity in human osteoblastic U2-OS cells through estrogen receptor (ER)alpha, and not through ER beta.
Quaedackers ME; Van Den Brink CE; Wissink S; Schreurs RH; Gustafsson JA; Van Der Saag PT; Van Der Burg BB
Article: JOURNAL OF CLINICAL INVESTIGATION. 2001;107(5):565-573
Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRβ-deficient mice
Alberti S; Schuster G; Parini P; Feltkamp D; Diczfalusy U; Rudling M; Angelin B; Björkhem I; Pettersson S; Gustafsson J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2001;98(5):2792-2796
Morphological abnormalities in the brains of estrogen receptor β knockout mice
Wang L; Andersson S; Warner M; Gustafsson J
Article: STRUCTURE. 2001;9(2):145-153
Structural insights into the mode of action of a pure antiestrogen.
Pike AC; Brzozowski AM; Walton J; Hubbard RE; Thorsell AG; Li YL; Gustafsson JA; Carlquist M
Article: DEVELOPMENTAL BIOLOGY. 2001;229(2):432-442
Evidence that epithelial and mesenchymal estrogen receptor-α mediates effects of estrogen on prostatic epithelium
Risbridger G; Wang H; Young P; Kurita T; Wong YZ; Lubahn D; Gustafsson JA; Cunha G
Article: ENDOCRINOLOGY. 2001;142(1):510-513
Estrogen receptor β regulates sexually dimorphic neural responses to estradiol
Temple JL; Fugger HN; Li X; Shetty SJ; Gustafsson J; Rissman EF
Article: BIOLOGY OF REPRODUCTION. 2001;64(1):272-283
Regulation of progesterone receptors and decidualization in uterine stroma of the estrogen receptor-α knockout mouse
Kurita T; Lee KJ; Saunders PTK; Cooke PS; Taylor JA; Lubahn DB; Zhao C; Mäkelä S; Gustafsson J; Dahiya R; Cunha GR
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(51):39855-39859
DAX-1 functions as an LXXLL-containing corepressor for activated estrogen receptors
Zhang H; Thomsen JS; Johansson L; Gustafsson J; Treuter E
Article: BIOCHEMISTRY. 2000;39(50):15585-15591
Ring opening of benzo[a]pyrene in the germ-free rat is a novel pathway for formation of potentially genotoxic metabolites
Yang Y; Griffiths WJ; Nordling M; Nygren J; Möller L; Bergman J; Liepinsh E; Otting G; Gustafsson J; Rafter J; Sjövall J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2000;97(26):14737-14741
Abolition of male sexual behaviors in mice lacking estrogen receptors α and β (αβERKO)
Ogawa S; Chester AE; Hewitt SC; Walker VR; Gustafsson J; Smithies O; Korach KS; Pfaff DW
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(50):39296-39301
Glucocorticoid receptor interaction with 14-3-3 and Raf-1, a proposed mechanism for cross-talk of two signal transduction pathways
Widén C; Zilliacus J; Gustafsson J; Wikström AC
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(48):37725-37732
The chitinase gene of the silkworm, Bombyx mori, contains a novel Tc-like transposable element.
Mikitani K; Sugasaki T; Shimada T; Kobayashi M; Gustafsson JA
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2000;278(3):640-645
Obesity and disturbed lipoprotein profile in estrogen receptor-α-deficient male mice
Ohlsson C; Hellberg N; Parini P; Vidal O; Bohlooly M; Rudling M; Lindberg MK; Warner M; Angelin B; Gustafsson J
Article: ONCOGENE. 2000;19(51):5951-5953
The hairy and enhancer of split homologue-1 (HES-1) mediates the proliferative effect of 17β-estradiol on breast cancer cell lines
Ström A; Arai N; Leers J; Gustafsson J
Article: BRAIN RESEARCH. 2000;883(2):258-264
Novel effects of estradiol and estrogen receptor alpha and beta on cognitive function.
Fugger HN; Foster TC; Gustafsson J; Rissman EF
Article: ONCOGENE. 2000;19(43):4970-4978
Estrogen receptor β acts as a dominant regulator of estrogen signaling
Pettersson K; Delaunay F; Gustafsson J
Article: AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2000;44(4):249-252
Maternal estrogen receptor-beta expression during mouse gestation.
Spong CY; McCune SK; Sternberg EM; Gustafsson JA
Article: ENDOCRINOLOGY. 2000;141(10):3792-3798
The differential fate of mesonephric tubular-derived efferent ductules in estrogen receptor-alpha knockout versus wild-type female mice.
Rosenfeld CS; Cooke PS; Welsh TH; Simmer G; Hufford MG; Gustafsson JA; Hess RA; Lubahn DB
Article: MECHANISMS OF DEVELOPMENT. 2000;97(1-2):13-26
Isolation and characterization of AINT:: a novel ARNT interacting protein expressed during murine embryonic development
Sadek CM; Jalaguier S; Feeney EP; Aitola M; Damdimopoulos AE; Pelto-Huikko M; Gustafsson J
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2000;85(10):3840-3846
Estrogen receptor beta (ERbeta) messenger ribonucleic acid (mRNA) expression within the human forebrain: distinct distribution pattern to ERalpha mRNA.
Osterlund MK; Gustafsson JA; Keller E; Hurd YL
Article: EUROPEAN JOURNAL OF CANCER. 2000;36 Suppl 4:S17-S18
Structural insights into the mechanisms of agonism and antagonism in oestrogen receptor isoforms.
Hubbard RE; Pike AC; Brzozowski AM; Walton J; Bonn T; Gustafsson JA; Carlquist M
Article: EUROPEAN JOURNAL OF CANCER. 2000;36 Suppl 4:S16-16
New insights in oestrogen receptor (ER) research - the ERbeta.
Gustafsson JA
Article: MOLECULAR PHARMACOLOGY. 2000;58(3):584-590
Functional differences between the amino-terminal domains of estrogen receptors α and β
Delaunay F; Pettersson K; Tujague M; Gustafsson J
Article: JOURNAL OF ENDOCRINOLOGY. 2000;166(2):R5-R9
Increased magnitude of relaxation to oestrogen in aorta from oestrogen receptor β knock-out mice
Nilsson BO; Ekblad E; Heine T; Gustafsson J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2000;274(1):87-92
Functional interaction of the immunosuppressant mizoribine with the 14-3-3 protein
Takahashi S; Wakui H; Gustafsson J; Zilliacus J; Itoh H
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2000;273(3):1008-1014
Glucocorticoid effects on NF-κB binding in the transcription of the ICAM-1 gene
Liden J; Rafter I; Truss M; Gustafsson J; Okret S
Article: JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA. 2000;5(3):289-294
The normal and malignant mammary gland: a fresh look with ER beta onboard.
Warner M; Saji S; Gustafsson JA
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2000;164(1-2):109-116
Differential expression of estrogen receptors alpha and beta in adult rat accessory sex glands and lower urinary tract.
Mäkelä S; Strauss L; Kuiper G; Valve E; Salmi S; Santti R; Gustafsson JA
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(21):16296-16301
Mitochondria of Saccharomyces cerevisiae contain one-conserved cysteine type peroxiredoxin with thioredoxin peroxidase activity.
Pedrajas JR; Miranda-Vizuete A; Javanmardy N; Gustafsson JA; Spyrou G
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2000;97(11):5936-5941
Estrogen receptor (ER) beta, a modulator of ERalpha in the uterus.
Weihua Z; Saji S; Mäkinen S; Cheng G; Jensen EV; Warner M; Gustafsson JA
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(20):15014-15018
Architectural principles for the structure and function of the glucocorticoid receptor τ1 core activation domain
Wärnmark A; Gustafsson J; Wright APH
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2000;97(10):5474-5479
Estrogen receptor specificity in the regulation of skeletal growth and maturation in male mice
Vidal O; Lindberg MK; Hollberg K; Baylink DJ; Andersson G; Lubahn DB; Mohan S; Gustafsson J; Ohlsson C
Article: MOLECULAR ENDOCRINOLOGY. 2000;14(5):741-752
Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-alpha.
Tobin KA; Steineger HH; Alberti S; Spydevold O; Auwerx J; Gustafsson JA; Nebb HI
Article: ENDOCRINOLOGY. 2000;141(5):1839-1845
Estradiol induces differential neuronal phenotypes by activating estrogen receptor α or β
Patrone C; Pollio G; Vegeto E; Enmark E; de Curtis I; Gustafsson J; Maggi A
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2000;12(5):1669-1678
Expression of novel antioxidant thioredoxin-2 in the rat brain
Rybnikova E; Damdimopoulos AE; Gustafsson J; Spyrou G; Pelto-Huikko M
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2000;270(2):425-431
Estrogen receptor β mRNA in colon cancer cells:: Growth effects of estrogen and genistein
Arai N; Ström A; Rafter JJ; Gustafsson J
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2000;22(4):469-480
C/EBPα and C/EBPδ activate the Clara cell secretory protein gene through interaction with two adjacent C/EBP-binding sites
Cassel TN; Nordlund-Möller L; Andersson O; Gustafsson J; Nord M
Article: TRENDS IN PHARMACOLOGICAL SCIENCES. 2000;21(3):85-87
Nematode genome sequence dramatically extends the nuclear receptor superfamily.
Enmark E; Gustafsson JA
Article: MOLECULAR AND CELLULAR BIOLOGY. 2000;20(6):2004-2013
Recruitment of the SWI-SNF chromatin remodeling complex as a mechanism of gene activation by the glucocorticoid receptor τ1 activation domain
Wallberg AE; Neely KE; Hassan AH; Gustafsson J; Workman JL; Wright APH
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(8):5379-5387
Ligand-, cell-, and estrogen receptor subtype (α/β)-dependent activation at GC-rich (Sp1) promoter elements
Saville B; Wormke M; Wang F; Nguyen T; Enmark E; Kuiper G; Gustafsson J; Safe S
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(8):5308-5317
Cloning and characterization of RAP250, a novel nuclear receptor coactivator
Caira F; Antonson P; Pelto-Huikko M; Treuter E; Gustafsson J
Article: GENE. 2000;243(1-2):93-103
Structural characterisation of the mouse nuclear oxysterol receptor genes LXRα and LXRβ
Alberti S; Steffensen KR; Gustafsson J
Article: BONE. 2000;26(2):117-121
Cellular distribution of estrogen receptor β in neonatal rat bone
Windahl SH; Norgård M; Kuiper GGJM; Gustafsson J; Andersson G
Article: MOLECULAR AND CELLULAR BIOLOGY. 2000;20(4):1124-1133
The orphan nuclear receptor SHP utilizes conserved LXXLL-related motifs for interactions with ligand-activated estrogen receptors
Johansson L; Båvner A; Thomsen JS; Färnegårdh M; Gustafsson J; Treuter E
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2000;97(1):337-342
Estrogen receptors α and β in the rodent mammary gland
Saji S; Jensen EV; Nilsson S; Rylander T; Warner M; Gustafsson J
Article: MOLECULAR CELL BIOLOGY RESEARCH COMMUNICATIONS. 2000;3(1):42-47
CYP2B1 is regulated by C/EBP alpha and C/EBP delta inlung epithelial cells.
Cassel TN; Gustafsson JA; Nord M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1999;96(26):15161-15166
Estradiol repression of tumor necrosis factor-alpha transcription requires estrogen receptor activation function-2 and is enhanced by coactivators.
An J; Ribeiro RC; Webb P; Gustafsson JA; Kushner PJ; Baxter JD; Leitman DC
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1999;96(26):15133-15136
Estrogen inhibits the vascular injury response in estrogen receptor beta-deficient female mice.
Karas RH; Hodgin JB; Kwoun M; Krege JH; Aronovitz M; Mackey W; Gustafsson JA; Korach KS; Smithies O; Mendelsohn ME
Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 1999;71(3-4):93-102
The nuclear-receptor interacting protein (RIP) 140 binds to the human glucocorticoid receptor and modulates hormone-dependent transactivation
Windahl SH; Treuter E; Ford J; Zilliacus J; Gustafsson J; McEwan IJ
Article: CHEMICAL RESEARCH IN TOXICOLOGY. 1999;12(12):1182-1189
Characterization of conjugated metabolites of benzo[a]pyrene in germ-free rat urine by liquid chromatography/electrospray tandem mass spectrometry
Yang Y; Griffiths WJ; Midtvedt T; Sjövall J; Rafter J; Gustafsson J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1999;265(2):569-571
Disproportional body growth in female estrogen receptor-α-inactivated mice
Vidal O; Lindberg M; Sävendahl L; Lubahn DB; Ritzen EM; Gustafsson J; Ohlsson C
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1999;96(22):12887-12892
Survival of reproductive behaviors in estrogen receptor β gene-deficient (βERKO) male and female mice
Ogawa S; Chan J; Chester AE; Gustafsson J; Korach KS; Pfaff DW
Article: MOLECULAR ENDOCRINOLOGY. 1999;13(10):1672-1685
The estrogen receptor enhances AP-1 activity by two distinct mechanisms with different requirements for receptor transactivation functions
Webb P; Nguyen P; Valentine C; Lopez GN; Kwok GR; McInerney E; Katzenellenbogen BS; Enmark E; Gustafsson J; Nilsson S; Kushner PJ
Article: JOURNAL OF CLINICAL INVESTIGATION. 1999;104(7):895-901
Increased cortical bone mineral content but exchanged trabecular bone mineral density in female ERβ^-/- mice
Windahl SH; Vidal O; Andersson G; Gustafsson JA; Ohlsson C
Article: EMBO JOURNAL. 1999;18(17):4608-4618
Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist
Pike ACW; Brzozowski AM; Hubbard RE; Bonn T; Thorsell AG; Engström O; Ljunggren J; Gustafsson JK; Carlquist M
Article: MOLECULAR AND CELLULAR BIOLOGY. 1999;19(9):5952-5959
Histone acetyltransferase complexes can mediate transcriptional activation by the major glucocorticoid receptor activation domain
Wallberg AE; Neely KE; Gustafsson J; Workman JL; Wright APH; Grant PA
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 1999;154(1-2):37-43
Cis desensitizes GH induced Stat5 signaling in rat liver cells
Karlsson H; Gustafsson J; Mode A
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1999;274(33):23368-23377
Rat peroxisome proliferator-activated receptors and brown adipose tissue function during cold acclimatization.
Guardiola-Diaz HM; Rehnmark S; Usuda N; Albrektsen T; Feltkamp D; Gustafsson JA; Alexson SE
Article: EMBO JOURNAL. 1999;18(15):4270-4279
Transcriptional targets shared by estrogen receptor-related receptors (ERRs) and estrogen receptor (ER) α, but not by ERβ
Vanacker JM; Pettersson K; Gustafsson J; Laudet V
Article: ENDOCRINOLOGY. 1999;140(7):2968-2975
Expression of peroxisome proliferator-activated receptor alpha messenger ribonucleic acid and protein in human and rat testis.
Schultz R; Yan W; Toppari J; Völkl A; Gustafsson JA; Pelto-Huikko M
Article: MOLECULAR ENDOCRINOLOGY. 1999;13(7):1105-1118
Ligand-independent coregulator recruitment by the triply activatable OR1/retinoid X receptor-α nuclear receptor heterodimer
Wiebel FF; Steffensen KR; Treuter E; Feltkamp D; Gustafsson J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1999;274(26):18515-18523
Valine 571 functions as a regional organizer in programming the glucocorticoid receptor for differential binding of glucocorticoids and mineralocorticoids
Lind U; Greenidge P; Gustafsson J; Wright APH; Carlstedt-Duke J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1999;96(12):7077-7082
Differentiation between vasculoprotective and uterotrophic effects of ligands with different binding affinities to estrogen receptors alpha and beta.
Mäkelä S; Savolainen H; Aavik E; Myllärniemi M; Strauss L; Taskinen E; Gustafsson JA; Häyry P
Article: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 1999;22(3):313-325
Selective activation of the probasin androgen-responsive region by steroid hormones
Kasper S; Rennie PS; Bruchovsky N; Lin L; Cheng H; Snoek R; Dahlman-Wright K; Gustafsson J; Shiu RPC; Sheppard PC; Matusik RJ
Article: CURRENT OPINION IN OBSTETRICS AND GYNECOLOGY. 1999;11(3):249-254
The estrogen receptor family
Warner M; Nilsson S; Gustafsson J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1999;274(15):10421-10429
Identification of a novel DNA binding site for nuclear orphan receptor OR1.
Feltkamp D; Wiebel FF; Alberti S; Gustafsson JA
Article: MOLECULAR ENDOCRINOLOGY. 1999;13(4):555-565
Extracellular signal-regulated kinase (ERK) interacts with signal transducer and activator of transcription (STAT) 5a
Pircher TJ; Petersen H; Gustafsson J; Haldosén LA
Article: THE FEBS JOURNAL. 1999;261(2):405-412
Human mitochondrial thioredoxin reductase -: cDNA cloning, expression and genomic organization
Miranda-Vizuete A; Damdimopoulos AE; Pedrajas JR; Gustafsson J; Spyrou G
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1999;274(10):6667-6677
Competition between thyroid hormone receptor-associated protein (TRAP) 220 and transcriptional intermediary factor (TIF) 2 for binding to nuclear receptors -: Implications for the recruitment of trap and P160 coactivator complexes
Treuter E; Johansson L; Thomsen JS; Wärnmark A; Leers J; Pelto-Huikko M; Sjöberg M; Wright APH; Spyrou G; Gustafsson JA
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1999;274(10):6366-6373
Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae
Pedrajas JR; Kosmidou E; Miranda-Vizuete A; Gustafsson J; Wright APH; Spyrou G
Article: MECHANISMS OF DEVELOPMENT. 1999;81(1-2):163-167
Expression of estrogen receptor alpha and beta during mouse embryogenesis.
Lemmen JG; Broekhof JL; Kuiper GG; Gustafsson JA; van der Saag PT; van der Burg B
Article: ENDOCRINOLOGY. 1999;140(1):478-483
Ontogeny of estrogen receptor-beta expression in rat testis.
van Pelt AM; de Rooij DG; van der Burg B; van der Saag PT; Gustafsson JA; Kuiper GG
Article: CYTOGENETIC AND GENOME RESEARCH. 1999;86(3-4):233-234
Assignment of estrogen receptor beta (Esr2) to rat chromosome band 6q24 and (Estrb) to mouse chromosome band 12D1-D3 by in situ hybridization.
Taguchi T; Gustafsson J; Yuri K
Article: JOURNAL OF MEDICINAL FOOD. 1999;2(3-4):161-162
Estrogen receptor beta and its interaction with phytoestrogens.
Gustafsson JA; Kuiper G
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1999;274(1):345-353
The orphan nuclear receptor SHP inhibits agonist-dependent transcriptional activity of estrogen receptors ERα and ERβ
Johansson L; Thomsen JS; Damdimopoulos AE; Spyrou G; Gustafsson J; Treuter E
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1998;95(26):15677-15682
Generation and reproductive phenotypes of mice lacking estrogen receptor beta.
Krege JH; Hodgin JB; Couse JF; Enmark E; Warner M; Mahler JF; Sar M; Korach KS; Gustafsson JA; Smithies O
Article: ENDOCRINOLOGY. 1998;139(10):4252-4263
Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta.
Kuiper GG; Lemmen JG; Carlsson B; Corton JC; Safe SH; van der Saag PT; van der Burg B; Gustafsson JA
Article: MOLECULAR AND CELLULAR BIOLOGY. 1998;18(10):6001-6013
Mechanistic principles in NR box-dependent interaction between nuclear hormone receptors and the coactivator TIF2
Leers J; Treuter E; Gustafsson J
Article: MOLECULAR PHARMACOLOGY. 1998;54(3):463-473
Down-regulation of cytochrome P450 2C family members and positive acute-phase response gene expression by peroxisome proliferator chemicals.
Corton JC; Fan LQ; Brown S; Anderson SP; Bocos C; Cattley RC; Mode A; Gustafsson JA
Article: MOLECULAR ENDOCRINOLOGY. 1998;12(9):1294-1309
IRE-ABP (insulin response element-A binding protein), an SRY-like protein, inhibits C/EBPα (CCAAT/enhancer-binding protein α)-stimulated expression of the sex-specific cytochrome P450 2C12 gene
Buggs C; Nasrin N; Mode A; Tollet P; Zhao HF; Gustafsson J; Alexander-Bridges M
Article: CIRCULATION RESEARCH. 1998;83(2):224-229
Increased expression of estrogen receptor-beta mRNA in male blood vessels after vascular injury.
Lindner V; Kim SK; Karas RH; Kuiper GG; Gustafsson JA; Mendelsohn ME
Article: MOLECULAR PHARMACOLOGY. 1998;54(1):105-112
Differential response of estrogen receptor alpha and estrogen receptor beta to partial estrogen agonists/antagonists.
Barkhem T; Carlsson B; Nilsson Y; Enmark E; Gustafsson J; Nilsson S
Article: TRENDS IN BIOCHEMICAL SCIENCES. 1998;23(7):233-235
Cross-talk between steroids and NF-κB:: what language?
Dumont A; Hehner SP; Schmitz ML; Gustafsson J; Lidén J; Okret S; Van der Saag PT; Wissink S; Van der Burg B; Herrlich P; Haegeman G; De Bosscher K; Fiers W
Article: BIOCHEMISTRY. 1998;37(26):9586-9594
Role of important hydrophobic amino acids in the interaction between the glucocorticoid receptor τ1-core activation domain and target factors
Almlöf T; Wallberg AE; Gustafsson J; Wright APH
Article: MOLECULAR ENDOCRINOLOGY. 1998;12(6):864-881
A regulatory role for RIP140 in nuclear receptor activation
Treuter E; Albrektsen T; Johansson L; Leers J; Gustafsson J
Article: DIABETOLOGIA. 1998;41(6):634-639
Increased glucocorticoid sensitivity in islet beta-cells:: effects on glucose 6-phosphatase, glucose cycling and insulin release
Ling ZC; Khan A; Delauny F; Davani B; Östenson CG; Gustafsson J; Okret S; Landau BR; Efendic S
Article: DNA AND CELL BIOLOGY. 1998;17(5):481-492
Regulation of CCSP (PCB-BP/uteroglobin) expression in primary cultures of lung cells:: Involvement of C/EBP
Nord M; Låg M; Cassel TN; Randmark M; Becher R; Barnes HJ; Schwarze PE; Gustafsson J; Lund J
Article: RAPID COMMUNICATIONS IN MASS SPECTROMETRY. 1998;12(8):465-471
Analysis of the major mercapturic acid pathway metabolites of benzo[a]pyrene found in rat urine by nano-electrospray mass spectrometry
Yang Y; Rafter J; Gustafsson JA; Sjovall J; Griffiths WJ
Article: ENDOCRINOLOGY. 1998;139(4):1815-1824
Desensitization of the growth hormone-induced Janus kinase 2 (Jak 2) signal transducer and activator of transcription 5 (Stat5)-signaling pathway requires protein synthesis and phospholipase C
Fernández L; Flores-Morales A; Lahuna O; Sliva D; Norstedt G; Haldosén LA; Mode A; Gustafsson J
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 1998;138(1-2):1-10
In vitro interaction between STAT5 and JAK2;: dependence upon phosphorylation status of STAT5 and JAK2
Flores-Morales A; Pircher TJ; Silvennoinen O; Gustafsson J; Sanchez-Gomez M; Norstedt G; Haldosén LA; Wood TJJ
Article: TRENDS IN PHARMACOLOGICAL SCIENCES. 1998;19(3):82-85
Cytochrome P450 in the brain:: 2B or not 2B
Hedlund E; Gustafsson J; Warner M
Article: MUTAGENESIS. 1998;13(2):167-171
Long-term effects of a change from a mixed diet to a lacto-vegetarian diet on human urinary and faecal mutagenic activity
Johansson G; Holmén A; Persson L; Högstedt B; Wassén C; Ottova L; Gustafsson J
Article: MOLECULAR PHARMACOLOGY. 1998;53(3):475-482
Identification of CYP2A3 as a major cytochrome P450 enzyme in the female peripubertal rat breast
Hellmold H; Magnusson M; Pelto-Huikko M; Rylander T; Gustafsson J; Warner M
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 1998;83(3):886-895
Characterization of cytochrome P450 enzymes in human breast tissue from reduction mammaplasties
Hellmold H; Rylander T; Magnusson M; Reihnér E; Warner M; Gustafsson JA
Article: ENDOCRINOLOGY. 1998;139(3):874-883
Estrogen receptor-β messenger ribonucleic acid ontogeny in the prostate of normal and neonatally estrogenized rats
Prins GS; Marmer M; Woodham C; Chang W; Kuiper G; Gustafsson JA; Birch L
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1998;243(3):657-663
Synergistic activation of RLD-1 by agents triggering PKA and PKC dependent signalling
Huang CJ; Feltkamp D; Nilsson S; Gustafsson JA
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1998;243(1):284-288
Molecular cloning and expression of a cDNA encoding a human thioredoxin-like protein.
Miranda-Vizuete A; Gustafsson JA; Spyrou G
Article: BRAIN RESEARCH. 1998;54(1):175-180
Differential distribution and regulation of estrogen receptor-alpha and -beta mRNA within the female rat brain.
Osterlund M; Kuiper GG; Gustafsson JA; Hurd YL
Article: METHODS IN MOLECULAR BIOLOGY. 1998;107:69-75
Purification of extrahepatic cytochromes P450.
Warner M; Gustafsson JA
Article: ARCHIVES OF TOXICOLOGY. SUPPLEMENT. ARCHIV F�R TOXIKOLOGIE. SUPPLEMENT. 1998;20:455-463
Extrahepatic cytochrome P450: role in in situ toxicity and cell-specific hormone sensitivity.
Warner M; Hellmold H; Magnusson M; Rylander T; Hedlund E; Gustafsson JA
Article: DNA AND CELL BIOLOGY. 1998;17(1):39-49
Identification of a functional glucocorticoid response element in the CYP3A1/IGC2 gene
Pereira TM; Carlstedt-Duke J; Leckner MC; Gustafsson J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1997;272(49):30841-30847
Cloning, expression, and characterization of a novel Escherichia coli thioredoxin
Miranda-Vizuete A; Damdimopoulos AE; Gustafsson JA; Spyrou G
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 1997;82(12):4258-4265
Human estrogen receptor β-gene structure, chromosomal localization, and expression pattern
Enmark E; Pelto-Huikko M; Grandien K; Lagercrantz S; Lagercrantz J; Fried G; Nordenskjöld M; Gustafsson J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1997;94(23):12309-12313
Expression of hepatocyte nuclear factor 6 in rat liver is sex-dependent and regulated by growth hormone
Lahuna O; Fernandez L; Karlsson H; Maiter D; Lemaigre FP; Rousseau GG; Gustafsson JA; Mode A
Article: ENDOCRINOLOGY. 1997;138(11):5067-5070
Differential expression of estrogen receptors alpha and beta mRNA during differentiation of human osteoblast SV-HFO cells.
Arts J; Kuiper GG; Janssen JM; Gustafsson JA; Löwik CW; Pols HA; van Leeuwen JP
Article: ENDOCRINOLOGY. 1997;138(11):4613-4621
Tissue distribution and quantitative analysis of estrogen receptor-alpha (ERalpha) and estrogen receptor-beta (ERbeta) messenger ribonucleic acid in the wild-type and ERalpha-knockout mouse.
Couse JF; Lindzey J; Grandien K; Gustafsson JA; Korach KS
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 1997;133(2):169-176
Mitogen-activated protein kinase kinase inhibition decreases growth hormone stimulated transcription mediated by STAT5
Pircher TJ; FloresMorales A; Mui ALF; Saltiel AR; Norstedt G; Gustafsson JA; Haldosen LA
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1997;272(42):26659-26664
Evidence that the beta-isoform of the human glucocorticoid receptor does not act as a physiologically significant repressor
Hecht K; CarlstedtDuke J; Stierna P; Gustafsson JA; Bronnegard M; Wikstrom AC
Article: NATURE. 1997;389(6652):753-758
Molecular basis of agonism and antagonism in the oestrogen receptor
Brzozowski AM; Pike ACW; Dauter Z; Hubbard RE; Bonn T; Engstrom O; Ohman L; Greene GL; Gustafsson JA; Carlquist M
Article: JOURNAL OF CLINICAL INVESTIGATION. 1997;100(8):2094-2098
Pancreatic beta cells are important targets for the diabetogenic effects of glucocorticoids
Delaunay F; Khan A; Cintra A; Davani B; Ling ZC; Andersson A; Ostenson CG; Gustafsson JA; Efendic S; Okret S
Article: SCIENCE. 1997;277(5331):1508-1510
Differential ligand activation of estrogen receptors ER alpha and ER beta at AP1 sites
Paech K; Webb P; Kuiper GGJM; Nilsson S; Gustafsson JA; Kushner PJ; Scanlan TS
Article: MOLECULAR ENDOCRINOLOGY. 1997;11(10):1486-1496
Mouse estrogen receptor beta forms estrogen response element-binding heterodimers with estrogen receptor alpha
Pettersson K; Grandien K; Kuiper GGJM; Gustafsson JA
Article: MOLECULAR ENDOCRINOLOGY. 1997;11(10):1467-1475
Involvement of the transcription factor IID protein complex in gene activation by the N-terminal transactivation domain of the glucocorticoid receptor in vitro
Ford J; McEwan IJ; Wright APH; Gustafsson JA
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1997;272(34):21467-21472
A new function for the C-terminal zinc finger of the glucocorticoid receptor - Repression of RelA transactivation
Liden J; Delaunay F; Rafter I; Gustafsson JA; Okret S
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1997;272(33):20954-20960
Promoter-dependent synergy between glucocorticoid receptor and Stat5 in the activation of beta-casein gene transcription.
Lechner J; Welte T; Tomasi JK; Bruno P; Cairns C; Gustafsson J; Doppler W
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1997;94(16):8485-8490
Interaction of the human androgen receptor transactivation function with the general transcription factor TFIIF.
McEwan IJ; Gustafsson J
Article: DNA AND CELL BIOLOGY. 1997;16(8):919-927
Glucocorticoid-dependent transcriptional repression of the osteocalcin gene by competitive binding at the TATA box.
Meyer T; Gustafsson JA; Carlstedt-Duke J
Article: STEROIDS. 1997;62(8-9):621-631
Characterization of bacterially expressed rat estrogen receptor beta ligand binding domain by mass spectrometry: Structural comparison with estrogen receptor alpha
Witkowska HE; Carlquist M; Engstrom O; Carlsson B; Bonn T; Gustafsson JA; Shackleton CHL
Article: MOLECULAR AND CELLULAR BIOLOGY. 1997;17(7):3977-3986
Heterodimeric interaction between retinoid X receptor alpha and orphan nuclear receptor OR1 reveals dimerization-induced activation as a novel mechanism of nuclear receptor activation.
Wiebel FF; Gustafsson JA
Article: MOLECULAR AND CELLULAR BIOLOGY. 1997;17(6):3065-3073
Role of the Ada adaptor complex in gene activation by the glucocorticoid receptor
Henriksson A; Almlof T; Ford J; McEwan IJ; Gustafsson JA; Wright APH
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 1997;129(2):169-179
CYP2C7 expression in rat liver and hepatocytes: Regulation by retinoids
Westin S; Sonneveld E; vanderLeede BM; vanderSaag PT; Gustafsson JA; Mode A
Article: BIOTECHNIQUES. 1997;22(5):802-passim
Increased efficiency in screening large numbers of cDNA fragments generated by differential display.
Corton JC; Gustafsson JA
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1997;272(13):8153-8156
Interaction of the ligand-activated glucocorticoid receptor with the 14-3-3 eta protein
Wakui H; Wright APH; Gustafsson JA; Zilliacus J
Article: ENDOCRINOLOGY. 1997;138(3):863-870
Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta
Kuiper GGJM; Carlsson B; Grandien K; Enmark E; Haggblad J; Nilsson S; Gustafsson JA
Article: MOLECULAR ENDOCRINOLOGY. 1997;11(2):172-182
Estrogen receptor-beta mRNA expression in rat ovary: down-regulation by gonadotropins.
Byers M; Kuiper GG; Gustafsson JA; Park-Sarge OK
Article: MOLECULAR AND CELLULAR BIOLOGY. 1997;17(2):934-945
Role of hydrophobic amino acid clusters in the transactivation activity of the human glucocorticoid receptor
Almlof T; Gustafsson JA; Wright APH
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1997;272(5):2936-2941
Cloning and expression of a novel mammalian thioredoxin.
Spyrou G; Enmark E; Miranda-Vizuete A; Gustafsson J
Article: CANCER EPIDEMIOLOGY. 1997;21(3):258-266
Dietary influence on some proposed risk factors for colon cancer: Fecal and urinary mutagenic activity and the activity of some intestinal bacterial enzymes
Johansson G; Holmen A; Persson L; Hogstedt B; Wassen C; Ottova L; Gustafsson JA
Article: JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY. 1997;8(1):50-61
Liquid chromatography mass spectrometry with collision-induced dissociation of conjugated metabolites of benzo[a]pyrene
Yang Y; Griffiths WJ; Sjovall J; Gustafsson JA; Rafter J
Article: BRAIN RESEARCH. 1996;743(1-2):315-319
Localization of the Rev-ErbA orphan receptors in the brain.
Kainu T; Enmark E; Gustafsson JA; Pelto-Huikko MP
Article: THE FEBS JOURNAL. 1996;242(3):839-845
Glucocorticoid receptor lacking the tau 1 transactivation domain ss a gene-specific regulator of the wild-type glucocorticoid-receptor activity
Delaunay F; Liden J; Gustafsson JA; Okret S
Article: MOLECULAR PHARMACOLOGY. 1996;50(5):1157-1166
Rat 17 beta-hydroxysteroid dehydrogenase type IV is a novel peroxisome proliferator-inducible gene.
Corton JC; Bocos C; Moreno ES; Merritt A; Marsman DS; Sausen PJ; Cattley RC; Gustafsson JA
Article: MOLECULAR ENDOCRINOLOGY. 1996;10(11):1358-1370
Identification of single amino acid substitutions of Cys-736 that affect the steroid-binding affinity and specificity of the glucocorticoid receptor using phenotypic screening in yeast
Lind U; CarlstedtDuke J; Gustafsson JA; Wright APH
Article: HEPATOLOGY. 1996;24(4):849-854
Role of the pituitary in tumor promotion with ethinyl estradiol in rat liver
Hallstrom IP; Liao DZ; AssefawRedda Y; Ohlson LCE; Sahlin L; Eneroth P; Eriksson LC; Gustafsson JA; Blanck A
Article: JOURNAL OF ENDOCRINOLOGY. 1996;150 Suppl:S241-S257
Ligands for orphan receptors?
Soontjens CD; Rafter JJ; Gustafsson JA
Article: MOLECULAR PHARMACOLOGY. 1996;50(3):538-548
Trans-activation by the human aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator proteins: direct interactions with basal transcription factors.
Rowlands JC; McEwan IJ; Gustafsson JA
Article: MOLECULAR PHARMACOLOGY. 1996;50(2):342-350
Cytochrome P4502D4 in the brain: Specific neuronal regulation by clozapine and toluene
Hedlund E; Wyss A; Kainu T; Backlund M; Kohler C; PeltoHuikko M; Gustafsson JA; Warner M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1996;93(12):5925-5930
Cloning of a novel estrogen receptor expressed in rat prostate and ovary
Kuiper GGJM; Enmark E; PeltoHuikko M; Nilsson S; Gustafsson JA
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1996;222(3):844-851
Expression of the peroxisome proliferator-activated receptor (PPAR) in the mouse colonic mucosa
Mansen A; GuardiolaDiaz H; Rafter J; Branting C; Gustafsson JA
Article: HEPATOLOGY. 1996;23(4):835-839
Persistent sex differences in growth control of early rat liver lesions are programmed during promotion in the resistant hepatocyte model.
Liao DZ; Porsch-Hällström I; Gustafsson JA; Blanck A
Article: CELLULAR AND MOLECULAR NEUROBIOLOGY. 1996;16(2):239-258
On the role of glucocorticoid receptors in brain plasticity
Fuxe K; Diaz R; Cintra A; Bhatnagar M; Tinner B; Gustafsson JA; Ogren SO; Agnati LF
Article: CANCER LETTERS. 1996;100(1-2):215-221
Expression of the c-jun, jun-B, ets-2 and liver regeneration factor-1 (LRF-1) genes during promotion and progression of rat liver carcinogenesis in the resistant hepatocyte model.
Liao DZ; Blanck A; Gustafsson JA; Hällström IP
Article: JOURNAL OF MOLECULAR BIOLOGY. 1996;256(2):392-404
Structural basis for calcium binding by uteroglobins
Barnes HJ; NordlundMoller L; Nord I; Andersson O; Gustafsson JA; Lund J; Gillner M
Article: JOURNAL OF MOLECULAR NEUROSCIENCE. 1996;7(1):29-39
Localization and ontogeny of the orphan receptor OR-1 in the rat brain.
Kainu T; Kononen J; Enmark E; Gustafsson JA; Pelto-Huikko M
Article: CHEMICAL RESEARCH IN TOXICOLOGY. 1996;9(6):1050-1056
P-32-HPLC analysis of DNA adducts formed in vitro and in vivo by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,4,8-trimethyl-3H-imidazo[4,5-f]quinoxaline, utilizing an improved adduct enrichment procedure
Wohlin P; Zeisig M; Gustafsson JA; Moller L
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(52):31353-31357
The basic helix-loop-helix/PAS factor Sim is associated with hsp90. Implications for regulation by interaction with partner factors.
McGuire J; Coumailleau P; Whitelaw ML; Gustafsson JA; Poellinger L
Article: NEUROREPORT. 1995;6(18):2557-2560
The dioxin receptor and its nuclear translocator (Arnt) in the rat brain.
Kainu T; Gustafsson JA; Pelto-Huikko M
Article: MOLECULAR ENDOCRINOLOGY. 1995;9(12):1771-1781
CCAAT/ENHANCER-BINDING PROTEIN-ALPHA-DEPENDENT TRANSACTIVATION OF CYP2C12 IN RAT HEPATOCYTES
TOLLET P; LAHUNA O; AHLGREN R; MODE A; GUSTAFSSON JA
Article: FEBS LETTERS. 1995;374(3):403-406
CALCIUM-DEPENDENT BINDING OF UTEROGLOBIN (PCB-BP/CCSP) TO NEGATIVELY CHARGED PHOSPHOLIPID LIPOSOMES
NORD M; GUSTAFSSON JA; LUND J
Article: MOLECULAR PHARMACOLOGY. 1995;48(5):938-945
Zinc ions antagonize the inhibitory effect of aurothiomalate on glucocorticoid receptor function at physiological concentrations.
Tanaka H; Makino Y; Dahlman-Wright K; Gustafsson JA; Okamoto K; Makino I; Wright KD [corrected to Dahlman-Wright K
Article: NATURE STRUCTURAL & MOLECULAR BIOLOGY. 1995;2(11):983-989
SOLUTION STRUCTURE OF A MAMMALIAN PCB-BINDING PROTEIN IN COMPLEX WITH A PCB
HARD T; BARNES HJ; LARSSON C; GUSTAFSSON JA; LUND J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(42):25291-25300
Definition of a minimal domain of the dioxin receptor that is associated with Hsp90 and maintains wild type ligand binding affinity and specificity.
Coumailleau P; Poellinger L; Gustafsson JA; Whitelaw ML
Article: MOLECULAR PHARMACOLOGY. 1995;48(4):630-638
DEVELOPMENTAL AND ENDOCRINE REGULATION OF P450 ISOFORMS IN RAT BREAST
HELLMOLD H; LAMB JG; WYSS A; GUSTAFSSON JA; WARNER M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(29):17535-17540
ROLE OF ACIDIC AND PHOSPHORYLATED RESIDUES IN GENE ACTIVATION BY THE GLUCOCORTICOID RECEPTOR
ALMLOF T; WRIGHT APH; GUSTAFSSON JA
Article: MOLECULAR PHARMACOLOGY. 1995;47(6):1148-1155
Cytochromes P450 of the 2D subfamily in rat brain.
Wyss A; Gustafsson JA; Warner M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(21):12569-12577
GROWTH-HORMONE SIGNALING LEADING TO CYP2C12 GENE-EXPRESSION IN RAT HEPATOCYTES INVOLVES PHOSPHOLIPASE A(2)
TOLLET P; HAMBERG M; GUSTAFSSON JA; MODE A
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(19):11276-11281
CHARACTERIZATION OF ORPHAN NUCLEAR RECEPTOR-BINDING ELEMENTS IN SEX-DIFFERENTIATED MEMBERS OF THE CYP2C GENE FAMILY EXPRESSED IN RAT-LIVER
STROM A; WESTIN S; EGUCHI H; GUSTAFSSON JA; MODE A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1995;92(10):4437-4441
Heat shock protein hsp90 regulates dioxin receptor function in vivo.
Whitelaw ML; McGuire J; Picard D; Gustafsson JA; Poellinger L
Article: ENDOCRINOLOGY. 1995;136(5):2223-2229
ESTROGEN TARGET TISSUE DETERMINES ALTERNATIVE PROMOTER UTILIZATION OF THE HUMAN ESTROGEN-RECEPTOR GENE IN OSTEOBLASTS AND TUMOR-CELL LINES
GRANDIEN K; BACKDAHL M; LJUNGGREN O; GUSTAFSSON JA; BERKENSTAM A
Article: MOLECULAR PHARMACOLOGY. 1995;47(5):940-947
SUPPRESSION OF THE CONSTITUTIVE EXPRESSION OF CYTOCHROME-P-450 2C11 BY CYTOKINES AND INTERFERONS IN PRIMARY CULTURES OF RAT HEPATOCYTES - COMPARISON WITH INDUCTION OF ACUTE-PHASE GENES AND DEMONSTRATION THAT CYP2C11 PROMOTER SEQUENCES ARE INVOLVED IN THE SUPPRESSIVE RESPONSE TO INTERLEUKIN-1 AND INTERLEUKIN-6
CHEN JQ; STROM A; GUSTAFSSON JA; MORGAN ET
Article: BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. 1995;76(5):328-333
Human dioxin receptor chimera transactivation in a yeast model system and studies on receptor agonists and antagonists.
Rowlands JC; Gustafsson JA
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 1995;110(1-2):49-54
GLUCOCORTICOID RECEPTOR INHIBITS MICROTUBULE ASSEMBLY IN-VITRO
AKNER G; WIKSTROM AC; STROMSTEDT PE; STOCKMAN O; GUSTAFSSON JK; WALLIN M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(16):9448-9453
MEDIATION OF GROWTH HORMONE-DEPENDENT TRANSCRIPTIONAL ACTIVATION BY MAMMARY-GLAND FACTOR STAT-5
WOOD TJJ; SLIVA D; LOBIE PE; PIRCHER TJ; GOUILLEUX F; WAKAO H; GUSTAFSSON JA; GRONER B; NORSTEDT G; HALDOSEN LA
Article: MOLECULAR ENDOCRINOLOGY. 1995;9(4):401-412
NEGATIVE CROSS-TALK BETWEEN RELA AND THE GLUCOCORTICOID RECEPTOR - A POSSIBLE MECHANISM FOR THE ANTIINFLAMMATORY ACTION OF GLUCOCORTICOIDS
CALDENHOVEN E; LIDEN J; WISSINK S; VANDESTOLPE A; RAAIJMAKERS J; KOENDERMAN L; OKRET S; GUSTAFSSON JA; VANDERSAAG PT
Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 1995;52(4):345-349
EXPRESSION OF HSP90-BETA MESSENGER-RIBONUCLEIC-ACID IN PATIENTS WITH FAMILIAL GLUCOCORTICOID RESISTANCE CORRELATION TO RECEPTOR STATUS
BRONNEGARD M; BOOS J; MARCUS C; MCGUIRE J; WERNER S; GUSTAFSSON JA
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1995;92(6):2096-2100
OR-1, A MEMBER OF THE NUCLEAR RECEPTOR SUPERFAMILY THAT INTERACTS WITH THE 9-CIS-RETINOIC ACID RECEPTOR
TEBOUL M; ENMARK E; LI Q; WIKSTROM AC; PELTOHUIKKO M; GUSTAFSSON JA
Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 1995;117(12):3319-3324
MASS-SPECTROMETRIC ANALYSIS OF A NATIVE ZINC-FINGER STRUCTURE - THE GLUCOCORTICOID RECEPTOR DNA-BINDING DOMAIN
WITKOWSKA HE; SHACKLETON CHL; DAHLMANWRIGHT K; KIM JY; GUSTAFSSON JA
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1995;92(5):1699-1703
STRUCTURAL CHARACTERIZATION OF A MINIMAL FUNCTIONAL TRANSACTIVATION DOMAIN FROM THE HUMAN GLUCOCORTICOID RECEPTOR
DAHLMANWRIGHT K; BAUMANN H; MCEWAN IJ; ALMLOF T; WRIGHT APH; GUSTAFSSON JA; HARD T
Article: CARCINOGENESIS. 1995;16(2):231-235
Hormonal regulation of sex differentiated parameters in liver nodules from rats treated in the resistant hepatocyte model.
Blanck A; Liao D; Gustafsson JA; Hällström IP
Article: MOLECULAR AND CELLULAR BIOLOGY. 1995;15(2):756-765
Distinct roles of the molecular chaperone hsp90 in modulating dioxin receptor function via the basic helix-loop-helix and PAS domains.
Antonsson C; Whitelaw ML; McGuire J; Gustafsson JA; Poellinger L
Article: PROTEINS: STRUCTURE, FUNCTION AND BIOINFORMATICS. 1995;21(1):57-67
MODULATION OF DNA-BINDING SPECIFICITY WITHIN THE NUCLEAR RECEPTOR FAMILY BY SUBSTITUTIONS AT A SINGLE AMINO-ACID POSITION
ZILLIACUS J; WRIGHT APH; CARLSTEDTDUKE J; NILSSON L; GUSTAFSSON JA
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A structural perspective of liver X receptors.
Gustafsson J-Å; Li XC; Suh JH; Lou X
Review: BIOMEDICINES. 2022;10(9):2165
Liver X Receptor Regulation of Glial Cell Functions in the CNS
Song X; Wu W; Warner M; Gustafsson J-A
Review: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 2021;68(1):R1-R9
25 years of ERβ: a personal journey
Warner M; Fan X; Strom A; Wu W; Gustafsson J-A
Review: TRENDS IN CANCER. 2021;7(6):541-556
Targeting Nuclear Receptors for Cancer Therapy: Premises, Promises, and Challenges
Yang Z; Gimple RC; Zhou N; Zhao L; Gustafsson J-A; Zhou S
Review: VITAMINS AND HORMONES. 2021;116:313-326
Estrogen receptor beta and neural development
Nalvarte I; Varshney M; Inzunza J; Gustafsson J-A
Review: TRENDS IN ENDOCRINOLOGY AND METABOLISM. 2020;31(2):93-106
Immunoregulatory Functions of Nuclear Receptors: Mechanisms and Therapeutic Implications
Zhao L; Gimple RC; Yang Z; Wei Y; Gustafsson J-A; Zhou S
Review: TRENDS IN IMMUNOLOGY. 2020;41(2):172-185
Nuclear Receptors in Cancer Inflammation and Immunity
Zhao L; Hu H; Gustafsson J-A; Zhou S
Review: ENDOCRINE REVIEWS. 2019;40(5):1207-1249
Nuclear Receptors: Recent Drug Discovery for Cancer Therapies
Zhao L; Zhou S; Gustafsson J-A
Corrigendum: JOURNAL OF ENDOCRINOLOGY. 2019;243(2):X1
The estrogen receptor α-selective agonist propyl pyrazole triol improves glucose tolerance in ob/ob mice: potential molecular mechanisms (vol 199, pg 275, 2008)
Lundholm L; Bryzgalova G; Gao H; Portwood N; Falt S; Berndt KD; Dicker A; Galuska D; Zierath JR; Gustafsson J-A; Efendic S; Dahlman-Wright K; Khan A
Review: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2019;489:119-125
Role of HSD17B13 in the liver physiology and pathophysiology
Su W; Mao Z; Liu Y; Zhang X; Zhang W; Gustafsson J-A; Guan Y
Corrigendum: SCIENTIFIC REPORTS. 2018;8(1):4262
Molecular mechanisms involved in the non-monotonic effect of bisphenol-a on Ca²⁺ entry in mouse pancreatic β-cells (vol 7, 2017)
Villar-Pazos S; Martinez-Pinna J; Castellano-Munoz M; Alonso-Magdalena P; Marroqui L; Quesada I; Gustafsson J-A; Nadal A
Review: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2017;169:10-21
On the regulatory importance of 27-hydroxycholesterol in mouse liver
Heverin M; Ali Z; Olin M; Tillander V; Joibari MM; Makoveichuk E; Leitersdorf E; Warner M; Olivercrona G; Gustafsson J-A; Bjorkhem I
Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 2017;38(1):92-99
Estrocen Receptor β as a Pharmaceutical Target
Warner M; Huang B; Gustafsson J-A
Editorial comment: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2016;157:1-2
Special Issue: Orphan Nuclear Receptors
Gustafsson J-A; Webb P
Review: CANCER LETTERS. 2016;372(1):48-56
Estrogen receptor beta as target for colorectal cancer prevention
Williams C; DiLeo A; Niv Y; Gustafsson J-A
Editorial comment: OBSTETRICAL AND GYNECOLOGICAL SURVEY. 2016;71(1):29-30
Adult Human and Mouse Ovaries Lack DDX4-Expressing Functional Oogonial Stem Cells EDITORIAL COMMENT
Zhang H; Panula S; Petropoulos S; Edsgard D; Busayavalasa K; Liu L; Li X; Risal S; Shen Y; Shao J; Liu M; Li S; Zhang D; Zhang X; Gerner RR; Sheikhi M; Damdimopoulou P; Sandberg R; Douagi I; Gustafsson J-A; Liu L; Lanner F; Hovatta O; Liu K
Review: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2015;418:240-244
Estrogen receptors in breast carcinogenesis and endocrine therapy
Huang B; Warner M; Gustafsson J-A
Letter: NATURE MEDICINE. 2015;21(10):1116-1118
Adult human and mouse ovaries lack DDX4-expressing functional oogonial stem cells
Zhang H; Panula S; Petropoulos S; Edsgard D; Busayavalasa K; Liu L; Li X; Risal S; Shen Y; Shao J; Liu M; Li S; Zhang D; Zhang X; Gerner RR; Sheikhi M; Damdimopoulou P; Sandberg R; Douagi I; Gustafsson J-A; Liu L; Lanner F; Hovatta O; Liu K
Review: NATURE REVIEWS CANCER. 2015;15(4):216-224
Targeting liver X receptors in cancer therapeutics
Lin C-Y; Gustafsson J-A
Review: MOLECULAR PSYCHIATRY. 2015;20(1):18-22
Estrogen receptor β and Liver X receptor β: biology and therapeutic potential in CNS diseases
Warner M; Gustafsson J-A
Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2015;1849(2):142-151
Estrogen receptor signaling during vertebrate development
Bondesson M; Hao R; Lin C-Y; Williams C; Gustafsson J-A
Editorial comment: ENDOCRINE. 2014;46(2):347-350
Selective blockade of estrogen receptor beta improves wound healing in diabetes
Sunkari VG; Botusan IR; Savu O; Grunler J; Zheng X; Gustafsson J-A; Brismar K; Catrina S-B
Review: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 2013;51(3):T61-T74
Insight into the mechanisms of action of estrogen receptor β in the breast, prostate, colon, and CNS
Dey P; Barros RPA; Warner M; Stroem A; Gustafsson J-A
Other: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2013;137:3-4
Elwood V. Jensen memorial letter
Gustafsson J-A
Review: EXPERT OPINION ON THERAPEUTIC TARGETS. 2013;17(8):977-990
Targeting liver X receptors in inflammation
Steffensen KR; Jakobsson T; Gustafsson J-A
Published conference paper: MOLECULAR MEMBRANE BIOLOGY. 2012;29(7):299-308
Influence of liver-X-receptor on tissue cholesterol, coenzyme Q and dolichol content
Bentinger M; Tekle M; Dallner G; Brismar K; Gustafsson J-A; Steffensen KR; Catrina S-B
Letter: HEPATOLOGY. 2012;56(5):2008-2009
Bile Acids in Nonalcoholic Steatohepatitis: Inserting Nuclear Receptors Into the Circle
Mao W
Review: STEROIDS. 2012;77(12):1262-1266
Current concepts and significance of estrogen receptor β in prostate cancer
Hartman J; Stroem A; Gustafsson J-A
Editorial comment: JOURNAL OF CLINICAL INVESTIGATION. 2012;122(8):2771-2773
Targeting PES1 for restoring the ERα/ERβ ratio in breast cancer
Thomas C; Gustafsson J-A
Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 2012;33(7):394-404
Liver X receptor biology and pharmacology: new pathways, challenges and opportunities
Jakobsson T; Treuter E; Gustafsson J-A; Steffensen KR
Review: JOURNAL OF ENDOCRINOLOGY. 2012;212(1):3-12
The diversity of sex steroid action: regulation of metabolism by estrogen signaling
Faulds MH; Zhao C; Dahlman-Wright K; Gustafsson J-A
Letter: NATURE REVIEWS CANCER. 2011;11(11):823
Not enough evidence to include ESR1 amplification
Thomas C; Gustafsson J-A
Review: NATURE REVIEWS DRUG DISCOVERY. 2011;10(10):778-792
Development of subtype-selective oestrogen receptor-based therapeutics
Nilsson S; Koehler KF; Gustafsson J-A
Review: CELL METABOLISM. 2011;14(3):289-299
Estrogen Receptors and the Metabolic Network
Barros RPA; Gustafsson J-A
Review: NATURE REVIEWS CANCER. 2011;11(8):597-608
The different roles of ER subtypes in cancer biology and therapy
Thomas C; Gustafsson J-A
Editorial comment: NATURE MEDICINE. 2011;17(6):658-660
A CUE hints at tumor resistance.
Thomas C; Gustafsson J-A
Review: BIRTH DEFECTS RESEARCH PART C - EMBRYO TODAY: REVIEWS. 2011;93(2):67-114
Developmental Toxicity Screening in Zebrafish
McCollum CW; Ducharme NA; Bondesson M; Gustafsson J-A
Review: GENOME MEDICINE. 2010;2(12):90
Does consuming isoflavones reduce or increase breast cancer risk?
Bondesson M; Gustafsson J-A
Review: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(51):39575-39579
Estrogen Signaling via Estrogen Receptor β
Zhao C; Dahlman-Wright K; Gustafsson J-A
Review: TRENDS IN ENDOCRINOLOGY AND METABOLISM. 2010;21(9):545-552
ERβ: recent understanding of estrogen signaling
Sugiyama N; Barros RPA; Warner M; Gustafsson J-A
Editorial comment: CANCER PREVENTION RESEARCH. 2010;3(8):897-899
Estrogen Receptors in Colorectal Cancer: Goalkeepers, Strikers, or Bystanders?
Hartman J; Gustafsson J-A
Published conference paper: INTERNATIONAL JOURNAL OF ANDROLOGY. 2010;33(2):288-297
Endocrine disruptors targeting ERβ function
Swedenborg E; Pongratz I; Gustafsson J-A
Review: TRAC. TRENDS IN ANALYTICAL CHEMISTRY. 2010;29(4):297-305
Nuclear receptors in analytics - a fruitful joint venture or a wasteful futility?
Fechner P; Gauglitz G; Gustafsson J-A
Review: PROGRESS IN BRAIN RESEARCH. 2010;181:233-250
ERβ in CNS: new roles in development and function
Fan X; Xu H; Warner M; Gustafsson J-A
Letter: REPRODUCTIVE TOXICOLOGY. 2009;28(4):563-567
A CASCADE of effects of bisphenol A
Bondesson M; Jonsson J; Pongratz I; Olea N; Cravedi J-P; Zalko D; Hakansson H; Halldin K; Di Lorenzo D; Behl C; Manthey D; Balaguer P; Demeneix B; Fini JB; Laudet V; Gustafsson J-A
Review: STEROIDS. 2009;74(8):635-641
Estrogen receptor beta in breast cancer-Diagnostic and therapeutic implications
Hartman J; Strom A; Gustafsson J-A
Meeting abstract: BONE. 2009;44:S155
The orphan nuclear receptor, Liver X Receptor, inhibits bone mineralisation
Robertson-Remen KM; Nilsson ME; Gustafsson JA; Andersson G
Meeting abstract: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2009;39:15
Clinical implications of the new biology of estrogen
Gustafsson J-A
Review: MOLECULAR ENDOCRINOLOGY. 2009;23(2):129-136
Minireview: Liver X Receptor β: Emerging Roles in Physiology and Diseases
Gabbi C; Warner M; Gustafsson J-A
Review: EXS. 2009;99:289-323
Receptors mediating toxicity and their involvement in endocrine disruption.
Rüegg J; Penttinen-Damdimopoulou P; Mäkelä S; Pongratz I; Gustafsson J-A
Review: JOURNAL OF INTERNAL MEDICINE. 2008;264(2):128-142
Biological functions and clinical implications of oestrogen receptors alfa and beta in epithelial tissues
Morani A; Warner M; Gustafsson J-A
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2008;9(1):25
BEXAROTENE-ACTIVATED RXR/LXR HETERODIMER IN LIVER MODULATES TRIGLYCERIDE METABOLISM BUT NOT CHOLESTEROL HOMEOSTASIS IN VIVO
Lalloyer F; Pedersen TA; Gross B; Yous S; Vallez E; Gustafsson JA; Mandrup S; Fievet C; Staels B; Tailleux A
Review: NUCLEAR RECEPTOR SIGNALING. 2008;6:e003
Estrogen receptor beta: an overview and update.
Zhao C; Dahlman-Wright K; Gustafsson J-A
Corrigendum: NUCLEIC ACIDS RESEARCH (NAR). 2008;36(1):352
Elk1 and SRF transcription factors convey basal transcription and mediate glucose response via their binding sites in the human LXRB gene promoter (vol 35, pg 4858, 2007)
Nilsson M; Dahlman-Wright K; Karelmo C; Ebeling M; Gustafsson J-A; Steffensen KR
Letter: MENOPAUSE. 2007;14(5):958-959
Untitled - Reply
Cheng G; Warner M; Gustafsson J-A; Landgren B-M
Review: PHYSIOLOGICAL REVIEWS. 2007;87(3):905-931
Estrogen receptors:: How do they signal and what are their targets
Heldring N; Pike A; Andersson S; Matthews J; Cheng G; Hartman J; Tujague M; Stroem A; Treuter E; Warner M; Gustafsson J-A
Editorial comment: MOLECULAR CELL. 2007;25(2):178-180
Wrestling rules in transrepression:: As easy as SUMO-1,-2,-3?
Treuter E; Gustafsson J-A
Review: PHARMACOLOGICAL REVIEWS. 2006;58(4):773-781
International Union of Pharmacology.: LXIV.: Estrogen receptors
Dahlman-Wright K; Cavailles V; Fuqua SA; Jordan VC; Katzenellenbogen JA; Korach KS; Maggi A; Muramatsu M; Parker MG; Gustafsson J-A
Published conference paper: BIOCHEMICAL SOCIETY TRANSACTIONS. 2006;34(Pt 6):1114-1116
New developments in oestrogen signalling in colonic epithelium
Wada-Hiraike O; Warner M; Gustafsson J-A
Review: ENDOCRINE REVIEWS. 2006;27(6):677-706
The hair follicle as an estrogen target and source
Ohnemus U; Uenalan M; Inzunza J; Gustafsson J-A; Paus R
Editorial comment: GENES AND NUTRITION. 2006;1(3-4):159-160
Comments to the paper "Tools To Evaluate Estrogenic Potency Of Dietary Phytoestrogens:: A Consensus Paper From The EU Thematic Network "Phytohealth" (QLKI-2002-2453)"
Gustafsson J-A
Review: TRENDS IN MOLECULAR MEDICINE. 2006;12(9):425-431
Estrogen receptors: new players in diabetes mellitus
Barros RPA; Machado UF; Gustafsson J-A
Corrigendum: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;348(1):326
Obesity and disturbed lipoprotein profile in estrogen receptor-α-deficient male mice (vol 278, pg 640, 2000)
Ohlsson C; Hellberg N; Parini P; Vidal O; Bohlooly-Y M; Rudling M; Lindberg MK; Warner M; Angelin B; Gustafsson J-A
Editorial comment: CLIMACTERIC. 2006;9(3):156-160
ERβ scientific visions translate to clinical uses
Gustafsson J-A
Review: CLINICAL LIPIDOLOGY. 2006;1(2):181-189
Liver X receptors: new drug targets to treat Type 2 diabetes?
Steffensen KR; Gustafsson J-A
Editorial comment: PUBLIC HEALTH NUTRITION. 2006;9(2):269-272
The Women's Health Initiative.: What is on trial:: nutrition and chronic disease?: Or misinterpreted science, media havoc and the sound of silence from peers?
Yngve A; Hambraeus L; Lissner L; Majem LS; de Almeida MDV; Berg C; Hughes R; Cannon G; Thorsdottir I; Kearney J; Gustafsson J; Rafter J; Elmadfa L; Kennedy N
Corrigendum: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006;103(21):8298
Estrogen receptor β inhibits 17β-estradiol-stimulated proliferation of the breast cancer cell line T47D (vol 101, pg 1566, 2004)
Ström A; Hartman J; Foster JS; Kietz S; Wimalasena J; Gustafsson JA
Review: DRUG METABOLISM REVIEWS. 2006;38(1-2):197-207
Sex and the liver -: A journey through five decades
Mode A; Gustafsson J
Review: ENDOCRINE. 2005;28(3):235-242
Estrogen action in mood and neurodegenerative disorders: estrogenic compounds with selective properties-the next generation of therapeutics.
Osterlund MK; Witt M-R; Gustafsson J-A
Review: TRENDS IN ENDOCRINOLOGY AND METABOLISM. 2005;16(10):478-488
Transcriptional corepression by SHP:: molecular mechanisms and physiological consequences
Båvner A; Sanyal S; Gustafsson J; Treuter E
Review: BIOLOGY OF REPRODUCTION. 2005;73(5):866-871
Estrogen receptor beta in health and disease.
Imamov O; Shim G-J; Warner M; Gustafsson J-A
Review: JOURNAL OF COMPARATIVE NEUROLOGY. 2005;488(2):152-179
Estrogen receptor-α and -β immunoreactive neurons in the brainstem and spinal cord of male and female mice:: Relationships to monoaminergic, cholinergic, and spinal projection systems
VanderHorst VGJM; Gustafsson J; Ulfhake B
Published conference paper: PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS. 2005;73(1):59-63
LXR is crucial in lipid metabolism.
Ulven SM; Dalen KT; Gustafsson J-A; Nebb HI
Meeting abstract: BREAST CANCER RESEARCH. 2005;7:S4-S5
ERβ in normal and malignant breast
Gustafsson J; Cheng G; Warner M
Review: ENDOCRINE REVIEWS. 2005;26(3):465-478
Reflections on the discovery and significance of estrogen receptor beta.
Koehler KF; Helguero LA; Haldosén L-A; Warner M; Gustafsson J-A
Review: CURRENT OPINION IN PHARMACOLOGY. 2005;5(2):171-176
Nuclear receptors and their relevance to diseases related to lipid metabolism.
Berkenstam A; Gustafsson J-A
Letter: NEW ENGLAND JOURNAL OF MEDICINE. 2004;351(26):2773-2774
Estrogen receptor beta in prostate cancer.
Imamov O; Lopatkin NA; Gustafsson J-A
Review: NATURE REVIEWS DRUG DISCOVERY. 2004;3(11):950-964
Principles for modulation of the nuclear receptor superfamily.
Gronemeyer H; Gustafsson J-A; Laudet V
Review: MECHANISMS OF AGEING AND DEVELOPMENT. 2004;125(10-11):707-717
Convergence of lipid homeostasis through liver X and thyroid hormone receptors.
Berkenstam A; Färnegårdh M; Gustafsson J-A
Review: ESSAYS IN BIOCHEMISTRY. 2004;40:157-167
Nuclear receptors in disease:: the oestrogen receptors
Nilsson M; Dahlman-Wright K; Gustafsson J
Published conference paper: DIABETES. 2004;53:S36-S42
Putative metabolic effects of the liver x receptor (LXR)
Steffensen KR; Gustafsson J
Review: ERNST SCHERING RESEARCH FOUNDATION WORKSHOP. 2004;(46):63-77
How to understand estrogen signaling from the phenotypes of ERalpha and ERbeta knockout mice.
Warner M; Gustafsson JA
Review: MOLECULAR DIAGNOSIS AND THERAPY. 2004;4(1):19-28
Molecular mechanisms, physiological consequences and pharmacological implications of estrogen receptor action.
Barkhem T; Nilsson S; Gustafsson J-A
Published conference paper: HORMONE RESEARCH IN PAEDIATRICS. 2004;62:115
Estrogen receptor-beta regulates epithelial cell differentiation in the mouse ventral prostate
Imamov O; Morani A; Shim GJ; Omoto Y; Warner M; Gustafsson J
Review: MOLECULAR ENDOCRINOLOGY. 2003;17(10):1901-1909
Activation functions 1 and 2 of nuclear receptors:: Molecular strategies for transcriptional activation
Wärnmark A; Treuter E; Wright APH; Gustafsson J
Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 2003;24(9):479-485
What pharmacologists can learn from recent advances in estrogen signalling.
Gustafsson J-A
Review: MOLECULAR INTERVENTIONS. 2003;3(5):281-292
Estrogen signaling: a subtle balance between ER alpha and ER beta.
Matthews J; Gustafsson J-A
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):40
Hypertension and abnormal heart pump function in mice deficient in ER-β
Bian Z; Meltser I; Pang YS; Thoren P; Gustafsson J
Review: METHODS IN ENZYMOLOGY. 2003;364:448-463
Analysis of estrogen receptor expression in tissues
Warner M; Wang L; Zhang WH; Cheng GJ; Sakaguchi H; Saji S; Nilsson S; Kiesselbach T; Gustafsson J
Review: MOLECULAR INTERVENTIONS. 2002;2(6):360-338
What is the value of measuring MTA-1s in breast cancer?
Cheng G; Imamov O; Omoto Y; Warner M; Gustafsson J-A
Published conference paper: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2002;193(1-2):1-5
Estrogen receptor beta in the prostate.
Weihua Z; Warner M; Gustafsson J-A
Review: TRENDS IN ENDOCRINOLOGY AND METABOLISM. 2002;13(5):195-200
Elucidation of estrogen receptor function in bone with the use of mouse models
Windahl SH; Andersson G; Gustafsson J
Review: SCIENCES STKE [ELECTRONIC RESOURCE] : SIGNAL TRANSDUCTION KNOWLEDGE ENVIRONMENT. 2002;2002(138):pe29
Estrogen actions in the brain.
Wang L; Andersson S; Warner M; Gustafsson J-A
Review: LAKARTIDNINGEN. 2002;99(11):1186-1190
[Nuclear receptors in man, fly and worm provide greater understanding of disease].
Enmark E; Gustafsson JA
Editorial comment: EMBO REPORTS. 2002;3(2):125-129
Looking at nuclear receptors from the heights of Erice -: Workshop on nuclear receptor structure and function
Ciana P; Vegeto E; Beato M; Chambon P; Gustafsson J; Parker M; Wahli W; Maggi A
Review: CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2002;37(1):1-28
Biological role of estrogen and estrogen receptors.
Nilsson S; Gustafsson J-A
Review: CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION. 2002;12(4):237-257
Estrogen receptor action.
Nilsson S; Gustafsson J-A
Editorial comment: TRENDS IN PHARMACOLOGICAL SCIENCES. 2001;22(12):611-615
Comparing nuclear receptors in worms, flies and humans.
Enmark E; Gustafsson JA
Meeting abstract: FERTILITY AND STERILITY. 2001;76(3):S212-S213
Estrogen receptor β is expressed in human endometrium and levels of expression vary during the menstrual cycle.
Hearns-Stokes RM; Mayers C; Segars JH; Stratton P; Gustafsson J; Nieman L
Review: CURRENT DRUG METABOLISM. 2001;2(3):245-263
Cytochrome P450 in the brain;: A review
Hedlund E; Gustafsson J; Warner M
Review: TRENDS IN CARDIOVASCULAR MEDICINE. 2001;11(5):196-202
Selective estrogen receptor modulators and coronary heart disease
Bian Z; Nilsson S; Gustafsson J
Review: PHYSIOLOGICAL REVIEWS. 2001;81(4):1535-1565
Mechanisms of estrogen action
Nilsson S; Mäkelä S; Treuter E; Tujague M; Thomsen J; Andersson G; Enmark E; Pettersson K; Warner M; Gustafsson J
Review: METHODS IN MOLECULAR BIOLOGY. 2001;176:201-226
Knockout mice and steroid receptor research.
Flodby P; Teglund S; Gustafsson JA
Review: ANNUAL REVIEW OF PHYSIOLOGY. 2001;63:165-192
Role of estrogen receptor beta in estrogen action
Pettersson K; Gustafsson J
Corrigendum: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2000;170(1-2):219-229
Differential expression of estrogen receptors alpha and beta in adult rat accessory sex glands and lower urinary tract.
Mäkelä S; Strauss L; Kuiper G; Valve E; Salmi S; Santti R; Gustafsson JA
Published conference paper: ACTA NEUROLOGICA SCANDINAVICA. 2000;102:27-28
Estrogens and neuropsychiatric disorders
Österlund MK; Overstreet DH; Gustafsson JA; Hurd YL
Published conference paper: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2000;74(5):245-248
Estrogen receptor beta in the breast: role in estrogen responsiveness and development of breast cancer.
Gustafsson JA; Warner M
Letter: THE LANCET. 2000;356(9233):944-945
False negatives in oestrogen-receptor assay.
Palmieri C; Saji S; Gustafsson JA; Coombes RC
Published conference paper: DEVELOPMENTAL NEUROSCIENCE. 2000;22(5-6):488-493
Maternal high n-6 polyunsaturated fatty acid intake during pregnancy increases voluntary alcohol intake and hypothalamic estrogen receptor alpha and beta levels among female offspring.
Cabanes A; de Assis S; Gustafsson JA; Hilakivi-Clarke L
Published conference paper: BIOCHEMICAL SOCIETY TRANSACTIONS. 2000;28(4):396-400
Structural aspects of agonism and antagonism in the oestrogen receptor.
Pike AC; Brzozowski AM; Walton J; Hubbard RE; Bonn T; Gustafsson JA; Carlquist M
Published conference paper: BIOCHEMICAL SOCIETY TRANSACTIONS. 2000;28(4):410-414
Recruitment of chromatin remodelling factors during gene activation via the glucocorticoid receptor N-terminal domain
Wallberg AE; Flinn EM; Gustafsson J; Wright APH
Review: NOVARTIS FOUNDATION SYMPOSIUM. 2000;230:7-14
Mechanism of oestrogen signalling with particular reference to the role of ER beta in the central nervous system.
Treuter E; Warner M; Gustafsson JA
Review: SEMINARS IN PERINATOLOGY. 2000;24(1):66-69
An update on estrogen receptors.
Gustafsson JA
Published conference paper: REPRODUCTIVE SCIENCES. 2000;7(1 Suppl):S8-S9
Novel aspects of estrogen action.
Gustafsson JA
Review: BREAST CANCER RESEARCH. 2000;2(5):360-366
Estrogen receptor transcription and transactivation -: Basic aspects of estrogen action
Nilsson S; Gustafsson J
Review: VITAMINS AND HORMONES. 2000;60:75-122
Chromatin-remodeling complexes involved in gene activation by the glucocorticoid receptor
Wallberg AE; Wright A; Gustafsson J
Review: JOURNAL OF ENDOCRINOLOGY. 1999;163(3):379-383
Estrogen receptor beta--a new dimension in estrogen mechanism of action.
Gustafsson JA
Review: JOURNAL OF INTERNAL MEDICINE. 1999;246(2):133-138
Oestrogen receptors - an overview.
Enmark E; Gustafsson JA
Editorial comment: SCIENCE. 1999;284(5418):1285-1286
Seeking ligands for lonely orphan receptors.
Gustafsson JA
Letter: CELL. 1999;97(2):161-163
A unified nomenclature system for the nuclear receptor superfamily
Auwerx J; Baulieu E; Beato M; Becker-Andre M; Burbach PH; Camerino G; Chambon P; Cooney A; Dejean A; Dreyer C; Evans RM; Gannon F; Giguere V; Gronemeyer H; Gustafson JA; Laudet V; Lazar MA; Mangelsdorf DJ; Milbrandt J; Milgrom E; Moore DD; O'Malley B; Parker M; Parker K; Perlmann T; Pfahl M; Rosenfeld MG; Samuels H; Schütz G; Sladek FM; Stunnenberg HG; Spedding M; Thummel C; Tsai MJ; Umesono K; Vennstrom B; Wahli W; Weinberger C; Willson TM; Yamamoto K
Editorial comment: SCIENTIST. 1999;13(13):9
Hot papers -: Endocrinology -: Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β by G.G.J.M.!Kuiper, B.!Carlsson, K.!Grandien, E.!Enmark, J.!Haggblad, S.!Nilsson, J.A.!Gustafsson -: Comments
Gustafsson J
Review: TRENDS IN ENDOCRINOLOGY AND METABOLISM. 1998;9(10):387-395
ERbeta: a novel estrogen receptor offers the potential for new drug development.
Nilsson S; Kuiper G; Gustafsson JA
Review: FRONTIERS IN NEUROENDOCRINOLOGY (FIN). 1998;19(4):253-286
The estrogen receptor beta subtype: a novel mediator of estrogen action in neuroendocrine systems.
Kuiper GG; Shughrue PJ; Merchenthaler I; Gustafsson JA
Review: ENDOCRINE-RELATED CANCER. 1998;5(3):213-222
Estrogen receptor β -: a novel receptor opens up new possibilities for cancer diagnosis and treatment
Enmark E; Gustafsson JA
Review: CURRENT OPINION IN CHEMICAL BIOLOGY. 1998;2(4):508-511
Therapeutic potential of selective estrogen receptor modulators.
Gustafsson JA
Review: LAKARTIDNINGEN. 1998;95(17):1945-1949
[Newly discovered estrogen receptor. New therapeutic possibilities in postmenopausal symptoms, osteoporosis, cancer of the breast and prostate].
Enmark E; Gustafsson JA
Published conference paper: GROWTH HORMONE AND IGF RESEARCH. 1998;8:61-67
Gender differences in rat hepatic CYP2C gene expression - regulation by growth hormone
Mode A; Ahlgren R; Lahuna O; Gustafsson JA
Editorial comment: NATURE MEDICINE. 1998;4(2):152-153
Raloxifene: magic bullet for heart and bone?
Gustafsson JA
Review: NUTRITION REVIEWS. 1998;56(2 Pt 2):s20-s21
Fatty acids in control of gene expression.
Gustafsson JA
Other: ARCHIVES OF TOXICOLOGY. SUPPLEMENT. ARCHIV F�R TOXIKOLOGIE. SUPPLEMENT. 1998;20:21-28
Receptor-mediated toxicity.
Gustafsson JA; Kuiper G; Enmark E; Treuter E; Rafter J
Review: VITAMINS AND HORMONES. 1998;54:121-166
Regulation of peroxisome proliferator-activated receptors
Sorensen HN; Treuter E; Gustafsson JA
Review: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND CELL BIOLOGY. 1997;29(12):1343-1369
The estrogen receptor gene: promoter organization and expression.
Grandien K; Berkenstam A; Gustafsson JA
Published conference paper: FEBS LETTERS. 1997;410(1):87-90
The novel estrogen receptor-beta subtype: potential role in the cell- and promoter-specific actions of estrogens and anti-estrogens.
Kuiper GG; Gustafsson JA
Published conference paper: MUTATION RESEARCH - FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. 1997;376(1-2):79-85
Cytochrome P450 in the breast and brain: Role in tissue-specific activation of xenobiotics
Warner M; Hellmold H; Yoshida S; Liao DZ; Hedlund E; Gustafsson JA
Editorial comment: NATURE MEDICINE. 1997;3(5):493-494
Estrogen receptor beta--getting in on the action?
Gustafsson JA
Review: TRENDS IN ENDOCRINOLOGY AND METABOLISM. 1997;8(4):152-157
Nuclear factor-kappa B repression in antiinflammation and immunosuppression by glucocorticoids
vanderBurg B; Liden J; Okret S; Delaunay F; Wissink S; vanderSaag PT; Gustafsson JA
Review: CRITICAL REVIEWS IN TOXICOLOGY. 1997;27(2):109-134
Aryl hydrocarbon receptor-mediated signal transduction.
Rowlands JC; Gustafsson JA
Published conference paper: BIOCHIMIE. 1997;79(2-3):151-162
Peroxisome proliferators alter the expression of estrogen-metabolizing enzymes.
Corton JC; Bocos C; Moreno ES; Merritt A; Cattley RC; Gustafsson JA
Review: BIOESSAYS. 1997;19(2):153-160
Mechanism of gene expression by the glucocorticoid receptor: Role of protein-protein interactions
McEwan IJ; Wright APH; Gustafsson JA
Letter: EUROPEAN JOURNAL OF MASS SPECTROMETRY. 1997;3(5):396-399
Letter: Differentiation of isomeric mercapturic acid pathway metabolites of benzo[a]pyrene
Yang Y; Rafter J; Gustafsson JA; Sjovall J; Griffiths WJ
Review: BIOLOGICAL CHEMISTRY. 1996;377(11):741-762
Interactions of procarcinogenic heterocyclic amines and indolocarbazoles with the dioxin receptor.
Kleman M; Gustafsson JA
Review: MOLECULAR ENDOCRINOLOGY. 1996;10(11):1293-1307
Orphan nuclear receptors--the first eight years.
Enmark E; Gustafsson JA
Published conference paper: TOXICOLOGY LETTERS. 1995;82-83:465-470
Receptor-mediated toxicity.
Gustafsson JA
Published conference paper: MUTATION RESEARCH - FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. 1995;333(1-2):15-22
Mechanisms of transcription activation by nuclear receptors: Studies on the human glucocorticoid receptor tau(1), transactivation domain
McEwan IJ; DahlmanWright K; Amlof T; Ford J; Wright APH; Gustafsson JA
Review: FRONTIERS IN NEUROENDOCRINOLOGY (FIN). 1995;16(3):224-236
Cytochrome P450 in the brain: neuroendocrine functions.
Warner M; Gustafsson JA
Published conference paper: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 1995;53(1-6):467-473
Fatty acid activation of peroxisome proliferator-activated receptor (PPAR).
Bocos C; Göttlicher M; Gearing K; Banner C; Enmark E; Teboul M; Crickmore A; Gustafsson JA
Review: MOLECULAR ENDOCRINOLOGY. 1995;9(4):389-400
STRUCTURAL DETERMINANTS OF DNA-BINDING SPECIFICITY BY STEROID-RECEPTORS
ZILLIACUS J; WRIGHT APH; CARLSTEDTDUKE J; GUSTAFSSON JA
Review: PRINCESS TAKAMATSU SYMP. 1995;23:163-171
Induction of cytochrome P4501A isozymes by heterocyclic amines and other food-derived compounds.
Kleman MI; Overvik E; Poellinger L; Gustafsson JA
Review: PRINCESS TAKAMATSU SYMP. 1995;23:123-133
Activation and effects of the food-derived heterocyclic amines in extrahepatic tissues.
Overvik E; Hellmold H; Branting C; Gustafsson JA
Review: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 1995;52(1):1-16
SUBCELLULAR-DISTRIBUTION OF THE GLUCOCORTICOID RECEPTOR AND EVIDENCE FOR ITS ASSOCIATION WITH MICROTUBULES
AKNER G; WIKSTROM AC; GUSTAFSSON JA
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