Tom Erkers

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: NPJ PRECISION ONCOLOGY. 2024;8(1):38

Delineating functional and molecular impact of ex vivo sample handling in precision medicine.

Struyf N; Österroos A; Vesterlund M; Arnroth C; James T; Sunandar S; Mermelekas G; Bohlin A; Hamberg Levedahl K; Bengtzén S; Jafari R; Orre LM; Lehtiö J; Lehmann S; Östling P; Kallioniemi O; Seashore-Ludlow B; Erkers T
Article: NPJ PRECISION ONCOLOGY. 2023;7(1):32

Prediction model for drug response of acute myeloid leukemia patients.

Trac QT; Pawitan Y; Mou T; Erkers T; Östling P; Bohlin A; Österroos A; Vesterlund M; Jafari R; Siavelis I; Bäckvall H; Kiviluoto S; Orre LM; Rantalainen M; Lehtiö J; Lehmann S; Kallioniemi O; Vu TN
Article: JOURNAL OF INTERNAL MEDICINE. 2022;292(6):925-940

Targeting SAMHD1 with hydroxyurea in first-line cytarabine-based therapy of newly diagnosed acute myeloid leukaemia: Results from the HEAT-AML trial.

Jädersten M; Lilienthal I; Tsesmetzis N; Lourda M; Bengtzén S; Bohlin A; Arnroth C; Erkers T; Seashore-Ludlow B; Giraud G; Barkhordar GS; Tao S; Fogelstrand L; Saft L; Östling P; Schinazi RF; Kim B; Schaller T; Juliusson G; Deneberg S; Lehmann S; Rassidakis GZ; Höglund M; Henter J-I; Herold N
Article: NATURE COMMUNICATIONS. 2022;13(1):1691

Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines.

Leo IR; Aswad L; Stahl M; Kunold E; Post F; Erkers T; Struyf N; Mermelekas G; Joshi RN; Gracia-Villacampa E; Östling P; Kallioniemi OP; Tamm KP; Siavelis I; Lehtiö J; Vesterlund M; Jafari R
Article: CANCER RESEARCH. 2021;81(22):5733-5744

MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia.

Sanjiv K; Calderón-Montaño JM; Pham TM; Erkers T; Tsuber V; Almlöf I; Höglund A; Heshmati Y; Seashore-Ludlow B; Nagesh Danda A; Gad H; Wiita E; Göktürk C; Rasti A; Friedrich S; Centio A; Estruch M; Våtsveen TK; Struyf N; Visnes T; Scobie M; Koolmeister T; Henriksson M; Wallner O; Sandvall T; Lehmann S; Theilgaard-Mönch K; Garnett MJ; Östling P; Walfridsson J; Helleday T; Warpman Berglund U
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2021;96(5):580-588

The transcriptome-wide landscape of molecular subtype-specific mRNA expression profiles in acute myeloid leukemia.

Mou T; Pawitan Y; Stahl M; Vesterlund M; Deng W; Jafari R; Bohlin A; Österroos A; Siavelis L; Bäckvall H; Erkers T; Kiviluoto S; Seashore-Ludlow B; Östling P; Orre LM; Kallioniemi O; Lehmann S; Lehtiö J; Vu TN
Article: BLOOD. 2020;135(11):814-825

High-parametric evaluation of human invariant natural killer T cells to delineate heterogeneity in allo- and autoimmunity.

Erkers T; Xie BJ; Kenyon LJ; Smith B; Rieck M; Jensen KP; Ji X; Basina M; Strober S; Negrin RS; Maecker HT; Meyer EH
Article: BLOOD ADVANCES. 2019;3(21):3419-3431

Blockade of TIM-1 on the donor graft ameliorates graft-versus-host disease following hematopoietic cell transplantation.

Iliopoulou BP; Hsu K; Pérez-Cruz M; Tang S-W; Pang WW; Erkers T; Kambham N; Freeman GJ; Dekruyff RH; Meyer EH
Article: JCI INSIGHT. 2017;2(20):92865

T cells expressing chimeric antigen receptor promote immune tolerance.

Pierini A; Iliopoulou BP; Peiris H; Pérez-Cruz M; Baker J; Hsu K; Gu X; Zheng P-P; Erkers T; Tang S-W; Strober W; Alvarez M; Ring A; Velardi A; Negrin RS; Kim SK; Meyer EH
Article: SCIENTIFIC REPORTS. 2017;7(1):6123

MAIT cells accumulate in placental intervillous space and display a highly cytotoxic phenotype upon bacterial stimulation.

Solders M; Gorchs L; Erkers T; Lundell A-C; Nava S; Gidlöf S; Tiblad E; Magalhaes I; Kaipe H
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2017;101(3):623-632

Frontline Science: Placenta-derived decidual stromal cells alter IL-2R expression and signaling in alloantigen-activated T cells.

Erkers T; Solders M; Verleng L; Bergström C; Stikvoort A; Rane L; Nava S; Ringdén O; Kaipe H
Article: FRONTIERS IN IMMUNOLOGY. 2017;8:1861

Mucosal-Associated Invariant T Cells Display a Poor Reconstitution and Altered Phenotype after Allogeneic Hematopoietic Stem Cell Transplantation.

Solders M; Erkers T; Gorchs L; Poiret T; Remberger M; Magalhaes I; Kaipe H
Article: STEM CELLS AND DEVELOPMENT. 2015;24(12):1471-1482

Immunogenicity of decidual stromal cells in an epidermolysis bullosa patient and in allogeneic hematopoietic stem cell transplantation patients.

Kaipe H; Carlson L-M; Erkers T; Nava S; Molldén P; Gustafsson B; Qian H; Li X; Hashimoto T; Sadeghi B; Alheim M; Ringdén O
Article: STEM CELLS AND DEVELOPMENT. 2015;24(2):253-263

Treatment of severe chronic graft-versus-host disease with decidual stromal cells and tracing with (111)indium radiolabeling.

Erkers T; Kaipe H; Nava S; Molldén P; Gustafsson B; Axelsson R; Ringdén O
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2014;20(9):1418-1425

Low CD34 dose is associated with poor survival after reduced-intensity conditioning allogeneic transplantation for acute myeloid leukemia and myelodysplastic syndrome.

Törlén J; Ringdén O; Le Rademacher J; Batiwalla M; Chen J; Erkers T; Ho V; Kebriaei P; Keever-Taylor C; Kindwall-Keller T; Lazarus HM; Laughlin MJ; Lill M; O'Brien T; Perales M-A; Rocha V; Savani BN; Szwajcer D; Valcarcel D; Eapen M
Article: ANALYST. 2013;138(21):6573-6581

Capture and separation of biomolecules using magnetic beads in a simple microfluidic channel without an external flow device.

Wang J; Morabito K; Erkers T; Tripathi A
Article: STEM CELLS AND DEVELOPMENT. 2013;22(19):2596-2605

Decidual stromal cells promote regulatory T cells and suppress alloreactivity in a cell contact-dependent manner.

Erkers T; Nava S; Yosef J; Ringdén O; Kaipe H
Article: JOURNAL OF INTERNAL MEDICINE. 2013;274(2):153-162

A prospective randomized toxicity study to compare reduced-intensity and myeloablative conditioning in patients with myeloid leukaemia undergoing allogeneic haematopoietic stem cell transplantation.

Ringdén O; Erkers T; Aschan J; Garming-Legert K; Le Blanc K; Hägglund H; Omazic B; Svenberg P; Dahllöf G; Mattsson J; Ljungman P; Remberger M
Article: STEM CELLS. 2013;31(3):592-601

Fetal membrane cells for treatment of steroid-refractory acute graft-versus-host disease.

Ringdén O; Erkers T; Nava S; Uzunel M; Iwarsson E; Conrad R; Westgren M; Mattsson J; Kaipe H
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2012;167(3):543-555

Stromal cells from term fetal membrane are highly suppressive in allogeneic settings in vitro.

Karlsson H; Erkers T; Nava S; Ruhm S; Westgren M; Ringdén O

Alla övriga publikationer

Meeting abstract: BLOOD. 2019;134:4641

High-Throughput Functional Ex-Vivo Drug Testing and Multi-Omics Profiling in Patients with Acute Myeloid Leukemia

Erkers T; Seashore-Ludlow B; Struyf N; Marabita F; James T; Malani D; Vesterlund M; Stalhl M; Pawitan Y; Lehmann S; Ostling P; Lehtio J; Kallioniemi O
Meeting abstract: BLOOD. 2018;132:2111

A Proinflammatory Invariant Natural Killer T Cells Phenotypic State Associates with Human Graft-Versus-Host Disease Onset and Response

Erkers T; Xei B; Kenyon L; Rieck M; Basina M; Jensen K; Strober S; Negrin RS; Maecker HT; Meyer EH
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2018;24(3):s324

Bone Morphogenetic Protein Signaling Pathway Modulation by Blocking Anti-Repulsive Guidance Molecule B Antibody Promotes Tolerance in Graft-Versus-Host Disease

Cruz MP; Hsu K; Iliopoulou BP; Erkers T; Pang W; Dekruyff RH; Freeman GJ; Meyer E
Review: STEM CELLS INTERNATIONAL. 2017;2017:5738371-17

Lymphocytes in Placental Tissues: Immune Regulation and Translational Possibilities for Immunotherapy.

Erkers T; Stikvoort A; Uhlin M
Meeting abstract: BLOOD. 2016;128(22):3355

The Use of Monoclonal Antibody Directed Chimeric Antigen Receptors to Facilitate Conventional T Cell and Treg Control of GvHD and Tissue Tolerance in Murine Models

Pierini A; Iliopoulou B; Peiris H; Cruz MP; Baker J; Hsu K; Strober W; Zheng P-P; Erkers T; Ring A; Velardi A; Negrin RS; Kim S; Meyer E
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2016;22(3):S48

Placenta-Derived Decidual Stromal Cells for Treatment of Severe Acute Graft-Versus-Host Disease

Ringden O; Solders M; Baygan A; Remberger M; Erkers T; Nava S; Gustavsson B; Winiarski J; Westgren M; Sadeghi B; Mattsson J; Kaipe H
KI thesis / dissertation: 2016

Immunoregulatory effects of placenta-derived decidual stromal cells

Erkers, Tom
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2015;21(2):S149

Placenta-Derived Decidual Stromal Cells for Graft-Versus-Host Disease, Hemorrhaging, and Toxicity after Allogeneic Hematopoietic Stem Cell Transplantation

Ringden O; Solders M; Erkers T; Nava S; Mollden P; Khoein B; Baygan A; Aronsson-Kurttila W; Mohmand S; Remberger M; Westgren M; Mattsson J; Sadeghi B; Kaipe H
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2015;21(2):S147

Immunological Effects of Decidual Stromal Cell Treatment in Patients with Severe Chronic Graft-Versus-Host Disease

Erkers T; Kaipe H; Nava S; Mollden P; Gustafsson B; Axelsson R; Ringden O
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2015;21(2):S349-S350

Decidual Stromal Cells As Treatment for Acute Graft Versus Host Disease

Solders M; Erkers T; Remberger M; Nava S; Mollden P; Mattsson J; Kaipe H; Ringden O
Review: BONE MARROW TRANSPLANTATION. 2014;49(6):737-743

Stromal cells-are they really useful for GVHD?

Kaipe H; Erkers T; Sadeghi B; Ringdén O
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2013;19(2):S141-S142

Fetal Membrane Cells for Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease

Ringden O; Erkers T; Nava S; Uzunel M; Iwarsson E; Conrad R; Westgren M; Mattsson J; Kaipe H
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2012;18(2):S335

A PROSPECTIVE RANDOMIZED STUDY COMPARING REDUCED-INTENSITY CONDITIONING AND MYELOABLATIVE CONDITIONING IN PATIENTS WITH MYELOID LEUKEMIA UNDERGOING ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION

Ringden O; Erkers T; Aschan J; Le Blanc K; Hagglund H; Omazic B; Svenberg P; Ljungman P; Mattsson J; Remberger M
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2012;18(2):S264

STROMAL CELLS ISOLATED FROM TERM FETAL MEMBRANE GREATLY SUPPRESS ALLOANTIGEN-STIMULATED IMMUNE CELLS IN VITRO

Erkers T; Nava S; Ruhm S; Westgren M; Ringden O; Karlsson H

Anställningar

Biträdande Lektor, Onkologi-Patologi, Karolinska Institutet, 2020-2024

Examina och utbildning

Medicine Doktorsexamen, Institutionen för laboratoriemedicin, Karolinska Institutet, 2016

Artiklar

Alla övriga publikationer

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI