Tim Willinger

Publikationer
CV
Populärvetenskap och samverkan

Utvalda publikationer

Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2022;219(2):e20210987

CD116+ fetal precursors migrate to the perinatal lung and give rise to human alveolar macrophages.

Evren E; Ringqvist E; Doisne J-M; Thaller A; Sleiers N; Flavell RA; Di Santo JP; Willinger T
Article: IMMUNITY. 2021;54(2):259-275.e7

Distinct developmental pathways from blood monocytes generate human lung macrophage diversity.

Evren E; Ringqvist E; Tripathi KP; Sleiers N; Rives IC; Alisjahbana A; Gao Y; Sarhan D; Halle T; Sorini C; Lepzien R; Marquardt N; Michaëlsson J; Smed-Sörensen A; Botling J; Karlsson MCI; Villablanca EJ; Willinger T
Review: IMMUNOLOGY. 2020;160(2):126-138

Origin and ontogeny of lung macrophages: from mice to humans.

Evren E; Ringqvist E; Willinger T
Article: IMMUNITY. 2018;48(1):120-132.e8

Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation.

Emgård J; Kammoun H; García-Cassani B; Chesné J; Parigi SM; Jacob J-M; Cheng H-W; Evren E; Das S; Czarnewski P; Sleiers N; Melo-Gonzalez F; Kvedaraite E; Svensson M; Scandella E; Hepworth MR; Huber S; Ludewig B; Peduto L; Villablanca EJ; Veiga-Fernandes H; Pereira JP; Flavell RA; Willinger T
Article: NATURE BIOTECHNOLOGY. 2014;32(4):364-372

Development and function of human innate immune cells in a humanized mouse model.

Rongvaux A; Willinger T; Martinek J; Strowig T; Gearty SV; Teichmann LL; Saito Y; Marches F; Halene S; Palucka AK; Manz MG; Flavell RA

Artiklar

Journal article: DISCOVERY IMMUNOLOGY. 2023;2(1):kyad007

Single-cell RNA sequencing of human lung innate lymphoid cells in the vascular and tissue niche reveals molecular features of tissue adaptation

Alisjahbana A; Mohammad I; Gao Y; Evren E; Willinger T
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:902881

A single-cell map of vascular and tissue lymphocytes identifies proliferative TCF-1+ human innate lymphoid cells.

Gao Y; Alisjahbana A; Boey DZH; Mohammad I; Sleiers N; Dahlin JS; Willinger T
Article: SCIENCE IMMUNOLOGY. 2021;6(56):eabb7800

Continuous human uterine NK cell differentiation in response to endometrial regeneration and pregnancy.

Strunz B; Bister J; Jönsson H; Filipovic I; Crona-Guterstam Y; Kvedaraite E; Sleiers N; Dumitrescu B; Brännström M; Lentini A; Reinius B; Cornillet M; Willinger T; Gidlöf S; Hamilton RS; Ivarsson MA; Björkström NK
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:752104

CD5 Surface Expression Marks Intravascular Human Innate Lymphoid Cells That Have a Distinct Ontogeny and Migrate to the Lung.

Alisjahbana A; Gao Y; Sleiers N; Evren E; Brownlie D; von Kries A; Jorns C; Marquardt N; Michaëlsson J; Willinger T
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2019;216(4):728-742

Antigen-presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria.

Melo-Gonzalez F; Kammoun H; Evren E; Dutton EE; Papadopoulou M; Bradford BM; Tanes C; Fardus-Reid F; Swann JR; Bittinger K; Mabbott NA; Vallance BA; Willinger T; Withers DR; Hepworth MR
Journal article: NATURE BIOTECHNOLOGY. 2017;35(12):1211

Corrigendum: Development and function of human innate immune cells in a humanized mouse model.

Rongvaux A; Willinger T; Martinek J; Strowig T; Gearty SV; Teichmann LL; Saito Y; Marches F; Halene S; Palucka AK; Manz MG; Flavell RA
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(14):4423-4428

Dynamin 2-dependent endocytosis sustains T-cell receptor signaling and drives metabolic reprogramming in T lymphocytes.

Willinger T; Staron M; Ferguson SM; De Camilli P; Flavell RA
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2014;211(4):685-700

Dynamin 2-dependent endocytosis is required for sustained S1PR1 signaling.

Willinger T; Ferguson SM; Pereira JP; De Camilli P; Flavell RA
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(22):8670-8675

Canonical autophagy dependent on the class III phosphoinositide-3 kinase Vps34 is required for naive T-cell homeostasis.

Willinger T; Flavell RA
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(6):2378-2383

Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo.

Rongvaux A; Willinger T; Takizawa H; Rathinam C; Auerbach W; Murphy AJ; Valenzuela DM; Yancopoulos GD; Eynon EE; Stevens S; Manz MG; Flavell RA
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(6):2390-2395

Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung.

Willinger T; Rongvaux A; Takizawa H; Yancopoulos GD; Valenzuela DM; Murphy AJ; Auerbach W; Eynon EE; Stevens S; Manz MG; Flavell RA
Article: CELL HOST & MICROBE. 2010;8(4):369-376

A mouse model for the human pathogen Salmonella typhi.

Song J; Willinger T; Rongvaux A; Eynon EE; Stevens S; Manz MG; Flavell RA; Galán JE
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(24):9785-9790

Requirement for AHNAK1-mediated calcium signaling during T lymphocyte cytolysis.

Matza D; Badou A; Jha MK; Willinger T; Antov A; Sanjabi S; Kobayashi KS; Marchesi VT; Flavell RA
Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2009;20(1):86-94

Disruption of Myosin 1e promotes podocyte injury.

Krendel M; Kim SV; Willinger T; Wang T; Kashgarian M; Flavell RA; Mooseker MS
Article: JOURNAL OF IMMUNOLOGY. 2006;176(3):1439-1446

Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo.

Willinger T; Freeman T; Herbert M; Hasegawa H; McMichael AJ; Callan MFC
Article: JOURNAL OF IMMUNOLOGY. 2005;175(9):5895-5903

Molecular signatures distinguish human central memory from effector memory CD8 T cell subsets.

Willinger T; Freeman T; Hasegawa H; McMichael AJ; Callan MFC
Article: BLOOD. 2001;97(10):3138-3145

Targeting of a B7-1 (CD80) immunoglobulin G fusion protein to acute myeloid leukemia blasts increases their costimulatory activity for autologous remission T cells.

Notter M; Willinger T; Erben U; Thiel E

Alla övriga publikationer

Editorial comment: CELLS. 2023;12(2):241

Implication of Oxysterols in Infectious and Non-Communicable Inflammatory Diseases.

Lizard G; Mackrill JJ; Willinger T
Book chapter: 2022;p. 190-199

Pulmonary Macrophages☆

Willinger T
Editorial comment: FRONTIERS IN IMMUNOLOGY. 2021;12:829644

Editorial: Advances in Human Immune System Mouse Models for Studying Human Hematopoiesis and Cancer Immunotherapy.

Saito Y; Willinger T; Theocharides APA
Review: BIOCHEMICAL PHARMACOLOGY. 2020;174:113672

Human macrophages and innate lymphoid cells: Tissue-resident innate immunity in humanized mice.

Alisjahbana A; Mohammad I; Gao Y; Evren E; Ringqvist E; Willinger T
Editorial comment: IMMUNITY. 2019;51(5):786-788

Metabolite Sensing by Colonic ILC3s: How Far Is Too Ffar2 Go?

Alisjahbana A; Willinger T
Review: JOURNAL OF INTERNAL MEDICINE. 2019;285(4):367-380

Oxysterols in intestinal immunity and inflammation.

Willinger T
Review: FRONTIERS IN IMMUNOLOGY. 2019;10:2010

Metabolic Control of Innate Lymphoid Cell Migration.

Willinger T
Editorial comment: CELL STEM CELL. 2014;14(1):3-4

ESCaping rejection: A step forward for embryonic-stem-cell-based regenerative medicine.

Willinger T; Flavell RA
Review: ANNUAL REVIEW OF IMMUNOLOGY. 2013;31:635-674

Human hemato-lymphoid system mice: current use and future potential for medicine.

Rongvaux A; Takizawa H; Strowig T; Willinger T; Eynon EE; Flavell RA; Manz MG
Review: TRENDS IN IMMUNOLOGY. 2011;32(7):321-327

Improving human hemato-lymphoid-system mice by cytokine knock-in gene replacement.

Willinger T; Rongvaux A; Strowig T; Manz MG; Flavell RA
Editorial comment: CELL HOST & MICROBE. 2009;6(1):5-9

Humanized mice for modeling human infectious disease: challenges, progress, and outlook.

Legrand N; Ploss A; Balling R; Becker PD; Borsotti C; Brezillon N; Debarry J; de Jong Y; Deng H; Di Santo JP; Eisenbarth S; Eynon E; Flavell RA; Guzman CA; Huntington ND; Kremsdorf D; Manns MP; Manz MG; Mention J-J; Ott M; Rathinam C; Rice CM; Rongvaux A; Stevens S; Spits H; Strick-Marchand H; Takizawa H; van Lent AU; Wang C; Weijer K; Willinger T; Ziegler P

Utvalda publikationer

Artiklar

Alla övriga publikationer

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI