Suhas Darekar

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: CELL DEATH DISCOVERY. 2022;8(1):464

Proof-of-principle studies on a strategy to enhance nucleotide imbalance specifically in cancer cells.

Alkasalias T; Zhang J; Madapura H; Dalarun B; Reina OB; Lewensohn R; Viktorsson K; Salihi A; Darekar S; Laín S
Article: ISCIENCE. 2021;24(5):102494

DHODH inhibition modulates glucose metabolism and circulating GDF15, and improves metabolic balance.

Zhang J; Terán G; Popa M; Madapura H; Ladds MJGW; Lianoudaki D; Grünler J; Arsenian-Henriksson M; McCormack E; Rottenberg ME; Catrina S-B; Laín S; Darekar S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(27):15673-15683

Cell stemness is maintained upon concurrent expression of RB and the mitochondrial ribosomal protein S18-2.

Mushtaq M; Kovalevska L; Darekar S; Abramsson A; Zetterberg H; Kashuba V; Klein G; Arsenian-Henriksson M; Kashuba E
Article: NATURE COMMUNICATIONS. 2018;9(1):1107

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Ladds MJGW; van Leeuwen IMM; Drummond CJ; Chu S; Healy AR; Popova G; Pastor Fernández A; Mollick T; Darekar S; Sedimbi SK; Nekulova M; Sachweh MCC; Campbell J; Higgins M; Tuck C; Popa M; Safont MM; Gelebart P; Fandalyuk Z; Thompson AM; Svensson R; Gustavsson A-L; Johansson L; Färnegårdh K; Yngve U; Saleh A; Haraldsson M; D'Hollander ACA; Franco M; Zhao Y; Håkansson M; Walse B; Larsson K; Peat EM; Pelechano V; Lunec J; Vojtesek B; Carmena M; Earnshaw WC; McCarthy AR; Westwood NJ; Arsenian-Henriksson M; Lane DP; Bhatia R; McCormack E; Laín S
Article: ONCOTARGET. 2017;8(39):64907-64917

Rat embryonic fibroblasts immortalized by MRPS18-2 protein are target for NK-cells.

Mushtaq M; Pangigadde PN; Darekar S; Dissen E; Kashuba E
Article: ONCOTARGET. 2015;6(25):21016-21028

Mitochondrial ribosomal protein S18-2 evokes chromosomal instability and transforms primary rat skin fibroblasts.

Darekar SD; Mushtaq M; Gurrapu S; Kovalevska L; Drummond C; Petruchek M; Tirinato L; Di Fabrizio E; Carbone E; Kashuba E
Article: PLOS ONE. 2015;10(8):e0136142

Different Mechanisms of Regulation of the Warburg Effect in Lymphoblastoid and Burkitt Lymphoma Cells.

Mushtaq M; Darekar S; Klein G; Kashuba E
Article: ACTA NATURAE. 2013;5(1):85-89

Overexpression of MRPS18-2 in Cancer Cell Lines Results in Appearance of Multinucleated Cells.

Shevchuk Z; Yurchenko MY; Darekar SD; Holodnuka-Kholodnyuk I; Kashuba VI; Kashuba EV
Article: ANALYST. 2012;137(16):3767-3772

Analysis of protein-protein interactions in a complex environment: capture of an analyte-receptor complex with standard additions of the receptor (CARSAR) approach.

Snopok BA; Darekar S; Kashuba EV
Article: CELL DEATH & DISEASE. 2012;3(1):e357

Stem cell gene expression in MRPS18-2-immortalized rat embryonic fibroblasts.

Yenamandra SP; Darekar SD; Kashuba V; Matskova L; Klein G; Kashuba E
Article: PLOS ONE. 2012;7(7):e42072

Epstein-Barr virus immortalization of human B-cells leads to stabilization of hypoxia-induced factor 1 alpha, congruent with the Warburg effect.

Darekar S; Georgiou K; Yurchenko M; Yenamandra SP; Chachami G; Simos G; Klein G; Kashuba E
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2010;67(24):4249-4256

Epstein-Barr virus encoded EBNA-3 binds to vitamin D receptor and blocks activation of its target genes.

Yenamandra SP; Hellman U; Kempkes B; Darekar SD; Petermann S; Sculley T; Klein G; Kashuba E
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(47):19866-19871

MRPS18-2 protein immortalizes primary rat embryonic fibroblasts and endows them with stem cell-like properties.

Kashuba E; Pavan Yenamandra S; Darekar SD; Yurchenko M; Kashuba V; Klein G; Szekely L

Alla övriga publikationer

Corrigendum: CELL DEATH DISCOVERY. 2022;8(1):472

Correction: Proof-of-principle studies on a strategy to enhance nucleotide imbalance specifically in cancer cells.

Alkasalias T; Zhang J; Madapura H; Dalarun B; Reina OB; Lewensohn R; Viktorsson K; Salihi A; Darekar S; Laín S
Corrigendum: NATURE COMMUNICATIONS. 2018;9(1):2071

Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Ladds MJGW; van Leeuwen IMM; Drummond CJ; Chu S; Healy AR; Popova G; Pastor Fernández A; Mollick T; Darekar S; Sedimbi SK; Nekulova M; Sachweh MCC; Campbell J; Higgins M; Tuck C; Popa M; Safont MM; Gelebart P; Fandalyuk Z; Thompson AM; Svensson R; Gustavsson A-L; Johansson L; Färnegårdh K; Yngve U; Saleh A; Haraldsson M; D'Hollander ACA; Franco M; Zhao Y; Håkansson M; Walse B; Larsson K; Peat EM; Pelechano V; Lunec J; Vojtesek B; Carmena M; Earnshaw WC; McCarthy AR; Westwood NJ; Arsenian-Henriksson M; Lane DP; Bhatia R; McCormack E; Laín S
Review: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2016;2016:6468342-9

DNA Tumor Viruses and Cell Metabolism.

Mushtaq M; Darekar S; Kashuba E
KI thesis / dissertation: 2013

The role of EBNA binding proteins in cell transformation

Darekar, Suhas

Anställningar

Senior Forskningsspecialist, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2019-

Examina och utbildning

Medicine Doktorsexamen, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2014

Artiklar

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Anställningar

Examina och utbildning

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