Stefano Gastaldello

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: CANCERS. 2024;16(5):853

Statin-Sensitive Akt1/Src/Caveolin-1 Signaling Enhances Oxidative Stress Resistance in Rhabdomyosarcoma.

Codenotti S; Sandrini L; Mandracchia D; Lorenzi L; Corsetti G; Poli M; Asperti M; Salvi V; Bosisio D; Monti E; Mitola S; Triggiani L; Guescini M; Pozzo E; Sampaolesi M; Gastaldello S; Cassandri M; Marampon F; Fanzani A
Article: ACTA PHYSIOLOGICA. 2022;236(3):e13869

Citrullination is linked to reduced Ca2+ sensitivity in hearts of a murine model of rheumatoid arthritis.

Pironti G; Gastaldello S; Rassier DE; Lanner JT; Carlström M; Lund LH; Westerblad H; Yamada T; Andersson DC
Article: CELLS. 2022;11(18):2859

Hyperactive Akt1 Signaling Increases Tumor Progression and DNA Repair in Embryonal Rhabdomyosarcoma RD Line and Confers Susceptibility to Glycolysis and Mevalonate Pathway Inhibitors.

Codenotti S; Zizioli D; Mignani L; Rezzola S; Tabellini G; Parolini S; Giacomini A; Asperti M; Poli M; Mandracchia D; Vezzoli M; Bernardi S; Russo D; Mitola S; Monti E; Triggiani L; Tomasini D; Gastaldello S; Cassandri M; Rota R; Marampon F; Fanzani A
Article: ANTIOXIDANTS. 2021;10(9):1443

Vitamin C and E Treatment Blocks Changes in Kynurenine Metabolism Triggered by Three Weeks of Sprint Interval Training in Recreationally Active Elderly Humans.

Wyckelsma VL; Trepci A; Schwieler L; Venckunas T; Brazaitis M; Kamandulis S; Paulauskas H; Gapeyeva H; Pääsuke M; Gastaldello S; Imbeault S; Westerblad H; Erhardt S; Andersson DC
Article: SCIENCE ADVANCES. 2021;7(36):eabi6856

Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine.

Zhou Y; Arribas GH; Turku A; Jürgenson T; Mkrtchian S; Krebs K; Wang Y; Svobodova B; Milani L; Schulte G; Korabecny J; Gastaldello S; Lauschke VM
Article: SCIENCE TRANSLATIONAL MEDICINE. 2021;13(603):eabf3637

Toward predicting CYP2D6-mediated variable drug response from CYP2D6 gene sequencing data.

van der Lee M; Allard WG; Vossen RHAM; Baak-Pablo RF; Menafra R; Deiman BALM; Deenen MJ; Neven P; Johansson I; Gastaldello S; Ingelman-Sundberg M; Guchelaar H-J; Swen JJ; Anvar SY
Article: CANCER LETTERS. 2021;505:1-12

Caveolin-1 promotes radioresistance in rhabdomyosarcoma through increased oxidative stress protection and DNA repair.

Codenotti S; Marampon F; Triggiani L; Bonù ML; Magrini SM; Ceccaroli P; Guescini M; Gastaldello S; Tombolini V; Poliani PL; Asperti M; Poli M; Monti E; Fanzani A
Article: TOXICON. 2021;192:46-56

Changes in basement membrane components in an experimental model of skeletal muscle degeneration and regeneration induced by snake venom and myotoxic phospholipase A2.

Escalante T; Saravia-Otten P; Gastaldello S; Hernández R; Marín A; García G; García L; Estrada E; Rucavado A; Gutiérrez JM
Article: EXPERIMENTAL CELL RESEARCH. 2020;395(2):112234

High glucose-induced oxidative stress accelerates myogenesis by altering SUMO reactions.

Liu X; Heras G; Lauschke VM; Mi J; Tian G; Gastaldello S
Article: ANTIOXIDANTS. 2020;9(9):E879-879

Vitamin C and E Treatment Blunts Sprint Interval Training-Induced Changes in Inflammatory Mediator-, Calcium-, and Mitochondria-Related Signaling in Recreationally Active Elderly Humans.

Wyckelsma VL; Venckunas T; Brazaitis M; Gastaldello S; Snieckus A; Eimantas N; Baranauskiene N; Subocius A; Skurvydas A; Pääsuke M; Gapeyeva H; Kaasik P; Pääsuke R; Jürimäe J; Graf BA; Kayser B; Place N; Andersson DC; Kamandulis S; Westerblad H
Article: FASEB JOURNAL. 2020;34(2):2269-2286

Expression of SUMO enzymes is fiber type dependent in skeletal muscles and is dysregulated in muscle disuse.

Namuduri AV; Heras G; Lauschke VM; Vitadello M; Traini L; Cacciani N; Gorza L; Gastaldello S
Article: JOURNAL OF MOLECULAR CELL BIOLOGY. 2019;11(5):356-370

Muscle RING-finger protein-1 (MuRF1) functions and cellular localization are regulated by SUMO1 post-translational modification.

Heras G; Namuduri AV; Traini L; Shevchenko G; Falk A; Bergström Lind S; Jia M; Tian G; Gastaldello S
Article: JOURNAL OF PATHOLOGY. 2018;246(4):433-446

Sarcolemmal loss of active nNOS (Nos1) is an oxidative stress-dependent, early event driving disuse atrophy.

Lechado I Terradas A; Vitadello M; Traini L; Namuduri AV; Gastaldello S; Gorza L
Article: SCIENTIFIC REPORTS. 2018;8(1):14199

Parkin-dependent regulation of the MCU complex component MICU1.

Matteucci A; Patron M; Vecellio Reane D; Gastaldello S; Amoroso S; Rizzuto R; Brini M; Raffaello A; Calì T
Article: MOLECULAR & CELLULAR PROTEOMICS. 2017;16(6):1081-1097

A Proteomic Approach to Identify Alterations in the Small Ubiquitin-like Modifier (SUMO) Network during Controlled Mechanical Ventilation in Rat Diaphragm Muscle.

Namuduri AV; Heras G; Mi J; Cacciani N; Hörnaeus K; Konzer A; Lind SB; Larsson L; Gastaldello S
Article: SCIENCE TRANSLATIONAL MEDICINE. 2016;8(350):350ra103

The chaperone co-inducer BGP-15 alleviates ventilation-induced diaphragm dysfunction.

Salah H; Li M; Cacciani N; Gastaldello S; Ogilvie H; Akkad H; Namuduri AV; Morbidoni V; Artemenko KA; Balogh G; Martinez-Redondo V; Jannig P; Hedström Y; Dworkin B; Bergquist J; Ruas J; Vigh L; Salviati L; Larsson L
Article: JOURNAL OF PHYSIOLOGY-LONDON. 2016;594(15):4371-4388

Mechano-signalling pathways in an experimental intensive critical illness myopathy model.

Corpeno Kalamgi R; Salah H; Gastaldello S; Martinez-Redondo V; Ruas JL; Fury W; Bai Y; Gromada J; Sartori R; Guttridge DC; Sandri M; Larsson L
Article: FEBS JOURNAL. 2014;281(21):4935-4950

Epstein-Barr virus encoded microRNAs target SUMO-regulated cellular functions.

Callegari S; Gastaldello S; Faridani OR; Masucci MG
Article: MUSCLE & NERVE. 2013;47(2):202-212

Homogenates of skeletal muscle injected with snake venom inhibit myogenic differentiation in cell culture.

Saravia-Otten P; Robledo B; Escalante T; Bonilla L; Rucavado A; Lomonte B; Hernández R; Flock J-I; Gutiérrez JM; Gastaldello S
Article: PLOS PATHOGENS. 2013;9(10):e1003664

Caspase-1 promotes Epstein-Barr virus replication by targeting the large tegument protein deneddylase to the nucleus of productively infected cells.

Gastaldello S; Chen X; Callegari S; Masucci MG
Article: PLOS ONE. 2013;8(5):e62783

Interaction of gamma-herpesvirus genome maintenance proteins with cellular chromatin.

Mughal N; Coppotelli G; Callegari S; Gastaldello S; Masucci MG
Article: JOURNAL OF MOLECULAR CELL BIOLOGY. 2012;4(4):242-251

Herpes virus deneddylases interrupt the cullin-RING ligase neddylation cycle by inhibiting the binding of CAND1.

Gastaldello S; Callegari S; Coppotelli G; Hildebrand S; Song M; Masucci MG
Article: INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY. 2011;301(3):213-224

Helicobacter pylori affects the cellular deubiquitinase USP7 and ubiquitin-regulated components TRAF6 and the tumour suppressor p53.

Coombs N; Sompallae R; Olbermann P; Gastaldello S; Göppel D; Masucci MG; Josenhans C
Article: PLOS BIOLOGY. 2010;8(11):e1000545

The translation initiation factor 3f (eIF3f) exhibits a deubiquitinase activity regulating Notch activation.

Moretti J; Chastagner P; Gastaldello S; Heuss SF; Dirac AM; Bernards R; Masucci MG; Israël A; Brou C
Article: NATURE CELL BIOLOGY. 2010;12(4):351-361

A deneddylase encoded by Epstein-Barr virus promotes viral DNA replication by regulating the activity of cullin-RING ligases.

Gastaldello S; Hildebrand S; Faridani O; Callegari S; Palmkvist M; Di Guglielmo C; Masucci MG
Article: EMBO REPORTS. 2009;10(7):755-761

The ER-resident ubiquitin-specific protease 19 participates in the UPR and rescues ERAD substrates.

Hassink GC; Zhao B; Sompallae R; Altun M; Gastaldello S; Zinin NV; Masucci MG; Lindsten K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(7):2313-2318

The Epstein-Barr virus nuclear antigen-1 promotes genomic instability via induction of reactive oxygen species.

Gruhne B; Sompallae R; Marescotti D; Kamranvar SA; Gastaldello S; Masucci MG
Article: JOURNAL OF VIROLOGY. 2008;82(21):10477-10486

Epstein-barr virus encodes three bona fide ubiquitin-specific proteases.

Sompallae R; Gastaldello S; Hildebrand S; Zinin N; Hassink G; Lindsten K; Haas J; Persson B; Masucci MG
Article: AMERICAN JOURNAL OF PATHOLOGY. 2008;173(1):170-181

Inhibition of proteasome activity promotes the correct localization of disease-causing alpha-sarcoglycan mutants in HEK-293 cells constitutively expressing beta-, gamma-, and delta-sarcoglycan.

Gastaldello S; D'Angelo S; Franzoso S; Fanin M; Angelini C; Betto R; Sandonà D
Article: FASEB JOURNAL. 2005;19(9):1184-1186

The T-tubule membrane ATP-operated P2X4 receptor influences contractility of skeletal muscle.

Sandonà D; Danieli-Betto D; Germinario E; Biral D; Martinello T; Lioy A; Tarricone E; Gastaldello S; Betto R
Article: CELL CALCIUM. 2005;37(2):129-136

Improved strategies for the delivery of GFP-based Ca2+ sensors into the mitochondrial matrix.

Filippin L; Abad MC; Gastaldello S; Magalhães PJ; Sandonà D; Pozzan T
Article: BIOCHEMICAL JOURNAL. 2004;381(Pt 1):105-112

Characterization of the ATP-hydrolysing activity of alpha-sarcoglycan.

Sandonà D; Gastaldello S; Martinello T; Betto R
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(10):5587-5593

Expression of cytochrome c oxidase during growth and development of Dictyostelium.

Sandonà D; Gastaldello S; Rizzuto R; Bisson R
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Corrigendum: SCIENTIFIC REPORTS. 2019;9(1):4665

Publisher Correction: Parkin-dependent regulation of the MCU complex component MICU1.

Matteucci A; Patron M; Vecellio Reane D; Gastaldello S; Amoroso S; Rizzuto R; Brini M; Raffaello A; Calì T
Review: TOXINS. 2018;10(5):E182-182

Why is Skeletal Muscle Regeneration Impaired after Myonecrosis Induced by Viperid Snake Venoms?

Gutiérrez JM; Escalante T; Hernández R; Gastaldello S; Saravia-Otten P; Rucavado A

Anställningar

Senior Forskningsspecialist, Fysiologi och farmakologi, Karolinska Institutet, 2022-

Examina och utbildning

Docent, Fysiologi, Karolinska Institutet, 2017

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