Olav Rooijackers

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Artiklar

Article: JOURNAL OF PARENTERAL AND ENTERAL NUTRITION. 2024

Plasma beta-hydroxy-beta-methylbutyrate availability after enteral administration during critical illness after trauma: An exploratory study.

Wittholz K; Bongetti AJ; Fetterplace K; Caldow MK; Karahalios A; De Souza DP; Elahee Doomun SN; Rooyackers O; Koopman R; Lynch GS; Ali Abdelhamid Y; Deane AM
Article: JOURNAL OF IMMUNOLOGY. 2024;212(3):389-396

Dynamic MAIT Cell Recovery after Severe COVID-19 Is Transient with Signs of Heterogeneous Functional Anomalies.

Kammann T; Gorin J-B; Parrot T; Gao Y; Ponzetta A; Emgård J; Maleki KT; Sekine T; Rivera-Ballesteros O; Karolinska COVID-19 Study Group; Gredmark-Russ S; Rooyackers O; Skagerberg M; Eriksson LI; Norrby-Teglund A; Mak JYW; Fairlie DP; Björkström NK; Klingström J; Ljunggren H-G; Aleman S; Buggert M; Strålin K; Sandberg JK
Article: AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY. 2023;325(5):G391-G397

Albumin and fibrinogen synthesis rates in advanced chronic liver disease.

Amouzandeh M; Sundström A; Wahlin S; Wernerman J; Rooyackers O; Norberg Å
Article: CANCERS. 2023;15(6):1843

Conditioned Media from Head and Neck Cancer Cell Lines and Serum Samples from Head and Neck Cancer Patients Drive Catabolic Pathways in Cultured Muscle Cells.

Saroul N; Tardif N; Pereira B; Dissard A; Montrieul L; Sanchez P; Salles J; Petersen JE; Jakobson T; Gilain L; Mom T; Boirie Y; Rooyakers O; Walrand S
Article: RESPIRATORY RESEARCH. 2023;24(1):62

Targeted plasma proteomics reveals signatures discriminating COVID-19 from sepsis with pneumonia.

Palma Medina LM; Babačić H; Dzidic M; Parke Å; Garcia M; Maleki KT; Unge C; Lourda M; Kvedaraite E; Chen P; Muvva JR; Cornillet M; Emgård J; Moll K; Karolinska K. I./K. COVID-19 Study Group; Michaëlsson J; Flodström-Tullberg M; Brighenti S; Buggert M; Mjösberg J; Malmberg K-J; Sandberg JK; Gredmark-Russ S; Rooyackers O; Svensson M; Chambers BJ; Eriksson LI; Pernemalm M; Björkström NK; Aleman S; Ljunggren H-G; Klingström J; Strålin K; Norrby-Teglund A
Article: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE. 2022;13(5):2551-2561

Sphingomyelinase activity promotes atrophy and attenuates force in human muscle fibres and is elevated in heart failure patients.

Olsson K; Cheng AJ; Al-Ameri M; Tardif N; Melin M; Rooyackers O; Lanner JT; Westerblad H; Gustafsson T; Bruton JD; Rullman E
Article: NUTRIENTS. 2022;14(18):3733

Variability in Skeletal Muscle Protein Synthesis Rates in Critically Ill Patients.

Tjäder I; Klaude M; Hssain AA; Guillet C; Nennesmo I; Wernerman J; Rooyackers O
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(1):e13195

The Karolinska KI/K COVID-19 Immune Atlas: An open resource for immunological research and educational purposes.

Ljunggren H-G; Ask EH; Cornillet M; Strunz B; Chen P; Rao Muvva J; Akber M; Buggert M; Chambers BJ; Cuapio A; Dzidic M; Filipovic I; Flodström-Tullberg M; Garcia M; Gorin J-B; Gredmark-Russ S; Hertwig L; Klingström J; Kokkinou E; Kvedaraite E; Lourda M; Mjösberg J; Maucourant C; Norrby-Teglund A; Palma Medina LM; Parrot T; Perez-Potti A; Ponzetta A; Ringqvist E; Rivera-Ballesteros O; Rooyackers O; Sandberg JK; Sandberg JT; Sekine T; Svensson M; Varnaite R; Wullimann D; Karolinska KI/K COVID-19 Study Group; Eriksson LI; Aleman S; Malmberg K-J; Strålin K; Björkström NK
Article: CRITICAL CARE. 2022;26(1):143

Medical nutrition therapy and clinical outcomes in critically ill adults: a European multinational, prospective observational cohort study (EuroPN).

Matejovic M; Huet O; Dams K; Elke G; Vaquerizo Alonso C; Csomos A; Krzych ŁJ; Tetamo R; Puthucheary Z; Rooyackers O; Tjäder I; Kuechenhoff H; Hartl WH; Hiesmayr M
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2022;52(3):503-510

COVID-19-specific metabolic imprint yields insights into multiorgan system perturbations.

Cornillet M; Strunz B; Rooyackers O; Ponzetta A; Chen P; Muvva JR; Akber M; Buggert M; Chambers BJ; Dzidic M; Filipovic I; Gorin J-B; Gredmark-Russ S; Hertwig L; Klingström J; Kokkinou E; Kvedaraite E; Lourda M; Mjösberg J; Maucourant C; Norrby-Teglund A; Parrot T; Perez-Potti A; Rivera-Ballesteros O; Sandberg JK; Sandberg JT; Sekine T; Svensson M; Varnaite R; Karolinska KI/K COVID-19 Study Group; Eriksson LI; Aleman S; Strålin K; Ljunggren H-G; Björkström NK
Article: PLOS ONE. 2022;17(10):e0276775

Fibrinogen and albumin synthesis rates in major upper abdominal surgery.

Dumitrescu G; Januszkiewicz A; Ågren A; Magnusson M; Sparrelid E; Rooyackers O; Wernerman J
Article: LAKARTIDNINGEN. 2021;118:21163

[Insights from creating a covid-19 biobank in Sweden].

Ljunggren H-G; Strålin K; Chen P; Cornillet M; Rooijackers O; I Eriksson L; Aleman S; Björkström N
Journal article: CLINICAL NUTRITION ESPEN. 2021;46:s644

Medical nutrition therapy in adult critically-ill intensive care unit (ICU) patients in Europe: results from the Europn study

Matejovic M; Huet O; Dams K; Elke G; Alonso CV; Csomos A; Krzych L; Tetamo R; Puthucheary Z; Rooyackers O; Tjäder I; Hartl W; Kuechenhoff H; Hiesmayr M; Group ES
Journal article: CLINICAL NUTRITION ESPEN. 2021;46:s642

Impact of medical nutrition therapy on clinical outcomes in adult critically ill intensive care unit (ICU) patients in Europe: results from the europn study

Matejovic M; Huet O; Dams K; Elke G; Alonso CV; Csomos A; Krzych L; Tetamo R; Puthucheary Z; Rooyackers O; Tjäder I; Hartl W; Kuechenhoff H; Hiesmayr M; Group ES
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(40):e2109123118

High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of granulocytes in COVID-19.

Lourda M; Dzidic M; Hertwig L; Bergsten H; Palma Medina LM; Sinha I; Kvedaraite E; Chen P; Muvva JR; Gorin J-B; Cornillet M; Emgård J; Moll K; García M; Maleki KT; Klingström J; Michaëlsson J; Flodström-Tullberg M; Brighenti S; Buggert M; Mjösberg J; Malmberg K-J; Sandberg JK; Henter J-I; Folkesson E; Gredmark-Russ S; Sönnerborg A; Eriksson LI; Rooyackers O; Aleman S; Strålin K; Ljunggren H-G; Björkström NK; Svensson M; Ponzetta A; Norrby-Teglund A; Chambers BJ; Karolinska KI/K COVID-19 Study Group
Article: CLINICAL NUTRITION ESPEN. 2021;45:322-332

Enteral nutrition and dynamics of citrulline and intestinal fatty acid-binding protein in adult ICU patients.

Padar M; Starkopf J; Starkopf L; Forbes A; Hiesmayr M; Jakob SM; Rooijackers O; Wernerman J; Ojavee SE; Reintam Blaser A
Article: CLINICAL NUTRITION. 2021;40(8):4932-4940

Development of the Gastrointestinal Dysfunction Score (GIDS) for critically ill patients - A prospective multicenter observational study (iSOFA study).

Reintam Blaser A; Padar M; Mändul M; Elke G; Engel C; Fischer K; Giabicani M; Gold T; Hess B; Hiesmayr M; Jakob SM; Loudet CI; Meesters DM; Mongkolpun W; Paugam-Burtz C; Poeze M; Preiser J-C; Renberg M; Rooijackers O; Tamme K; Wernerman J; Starkopf J
Article: CRITICAL CARE. 2021;25(1):240

Plasma glutamine status at intensive care unit admission: an independent risk factor for mortality in critical illness.

Smedberg M; Helleberg J; Norberg Å; Tjäder I; Rooyackers O; Wernerman J
Article: CLINICAL NUTRITION. 2021;40(7):4526-4534

The effect of glucose control in liver surgery on glucose kinetics and insulin resistance.

Blixt C; Larsson M; Isaksson B; Ljungqvist O; Rooyackers O
Article: CLINICAL NUTRITION ESPEN. 2021;43:104-110

Protocol for a prospective cohort study on the use of clinical nutrition and assessment of long-term clinical and functional outcomes in critically ill adult patients.

Hiesmayr M; Csomos A; Dams K; Elke G; Hartl W; Huet O; Krzych LJ; Kuechenhoff H; Matejovic M; Puthucheary ZA; Rooyackers O; Tetamo R; Tjäder I; Vaquerizo C
Article: MOLECULAR THERAPY. 2021;29(5):1903-1917

Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes.

Zabulica M; Srinivasan RC; Akcakaya P; Allegri G; Bestas B; Firth M; Hammarstedt C; Jakobsson T; Jakobsson T; Ellis E; Jorns C; Makris G; Scherer T; Rimann N; van Zuydam NR; Gramignoli R; Forslöw A; Engberg S; Maresca M; Rooyackers O; Thöny B; Häberle J; Rosen B; Strom SC
Article: CLINICAL NUTRITION. 2021;40(3):912-918

Uptake of dietary amino acids into arterial blood during continuous enteral feeding in critically ill patients and healthy subjects.

Liebau F; Király E; Olsson D; Wernerman J; Rooyackers O
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(6):e2018587118

Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity.

Kvedaraite E; Hertwig L; Sinha I; Ponzetta A; Hed Myrberg I; Lourda M; Dzidic M; Akber M; Klingström J; Folkesson E; Muvva JR; Chen P; Gredmark-Russ S; Brighenti S; Norrby-Teglund A; Eriksson LI; Rooyackers O; Aleman S; Strålin K; Ljunggren H-G; Ginhoux F; Björkström NK; Henter J-I; Svensson M; Karolinska KI/K COVID-19 Study Group
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(3):1217

Gene Editing Correction of a Urea Cycle Defect in Organoid Stem Cell Derived Hepatocyte-like Cells.

Zabulica M; Jakobsson T; Ravaioli F; Vosough M; Gramignoli R; Ellis E; Rooyackers O; Strom SC
Article: TRANSPLANTATION PROCEEDINGS. 2021;53(1):130-135

Intrahepatic Microdialysis for Monitoring of Metabolic Markers to Detect Rejection Early After Liver Transplantation.

von Platen A; D'Souza MA; Rooyackers O; Nowak G
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(7):e1306

SARS-CoV-2-specific humoral and cellular immunity persists through 9 months irrespective of COVID-19 severity at hospitalisation.

Sandberg JT; Varnaitė R; Christ W; Chen P; Muvva JR; Maleki KT; García M; Dzidic M; Folkesson E; Skagerberg M; Ahlén G; Frelin L; Sällberg M; Eriksson LI; Rooyackers O; Sönnerborg A; Buggert M; Björkström NK; Aleman S; Strålin K; Klingström J; Ljunggren H-G; Blom K; Gredmark-Russ S; Karolinska COVID‐19 Study Group
Article: CLINICAL NUTRITION ESPEN. 2020;40:226-230

Endogenous production of glutamine and plasma glutamine concentration in critically ill patients.

Smedberg M; Rooyackers O; Norberg Å; Tjäder I; Wernerman J
Article: CELL. 2020;183(1):158-168.e14

Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19.

Sekine T; Perez-Potti A; Rivera-Ballesteros O; Strålin K; Gorin J-B; Olsson A; Llewellyn-Lacey S; Kamal H; Bogdanovic G; Muschiol S; Wullimann DJ; Kammann T; Emgård J; Parrot T; Folkesson E; Karolinska COVID-19 Study Group; Rooyackers O; Eriksson LI; Henter J-I; Sönnerborg A; Allander T; Albert J; Nielsen M; Klingström J; Gredmark-Russ S; Björkström NK; Sandberg JK; Price DA; Ljunggren H-G; Aleman S; Buggert M
Article: SCIENCE IMMUNOLOGY. 2020;5(51):eabe1670

MAIT cell activation and dynamics associated with COVID-19 disease severity.

Parrot T; Gorin J-B; Ponzetta A; Maleki KT; Kammann T; Emgård J; Perez-Potti A; Sekine T; Rivera-Ballesteros O; Karolinska COVID-19 Study Group; Gredmark-Russ S; Rooyackers O; Folkesson E; Eriksson LI; Norrby-Teglund A; Ljunggren H-G; Björkström NK; Aleman S; Buggert M; Klingström J; Strålin K; Sandberg JK
Article: SCIENCE IMMUNOLOGY. 2020;5(50):eabd6832

Natural killer cell immunotypes related to COVID-19 disease severity.

Maucourant C; Filipovic I; Ponzetta A; Aleman S; Cornillet M; Hertwig L; Strunz B; Lentini A; Reinius B; Brownlie D; Cuapio A; Ask EH; Hull RM; Haroun-Izquierdo A; Schaffer M; Klingström J; Folkesson E; Buggert M; Sandberg JK; Eriksson LI; Rooyackers O; Ljunggren H-G; Malmberg K-J; Michaëlsson J; Marquardt N; Hammer Q; Strålin K; Björkström NK; Karolinska COVID-19 Study Group
Article: CRITICAL CARE. 2020;24(1):46

Lactate kinetics in ICU patients using a bolus of 13C-labeled lactate.

Grip J; Falkenström T; Promsin P; Wernerman J; Norberg Å; Rooyackers O
Article: CELL METABOLISM. 2020;31(2):375-390.e11

Glutamine Links Obesity to Inflammation in Human White Adipose Tissue.

Petrus P; Lecoutre S; Dollet L; Wiel C; Sulen A; Gao H; Tavira B; Laurencikiene J; Rooyackers O; Checa A; Douagi I; Wheelock CE; Arner P; McCarthy M; Bergo MO; Edgar L; Choudhury RP; Aouadi M; Krook A; Rydén M
Article: PLOS ONE. 2020;15(10):e0240045

Whole-body protein kinetics in critically ill patients during 50 or 100% energy provision by enteral nutrition: A randomized cross-over study.

Sundström Rehal M; Liebau F; Wernerman J; Rooyackers O
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2020;9(12):e1224

Innate lymphoid cell composition associates with COVID-19 disease severity.

García M; Kokkinou E; Carrasco García A; Parrot T; Palma Medina LM; Maleki KT; Christ W; Varnaitė R; Filipovic I; Ljunggren H-G; Björkström NK; Folkesson E; Rooyackers O; Eriksson LI; Sönnerborg A; Aleman S; Strålin K; Gredmark-Russ S; Klingström J; Mjösberg J; Karolinska KI/K COVID‐19 Study Group
Article: BMJ OPEN. 2019;9(12):e032650

Patients' experiences of early postoperative cognition and its relation to cognitive decline and inflammatory responses: a protocol for a mixed-methods study.

Nilsson U; Liander K; Rooyackers O; Eriksson LI
Article: TRANSPLANTATION DIRECT. 2019;5(12):e505

Evaluation of Intrahepatic Lactate/Pyruvate Ratio As a Marker for Ischemic Complications Early After Liver Transplantation-A Clinical Study.

von Platen A; D'Souza MA; Rooyackers O; Nowak G
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2019;63(7):885-894

Optimal cut-off for hourly lactate reduction in ICU-treated patients with septic shock.

Promsin P; Grip J; Norberg Å; Wernerman J; Rooyackers O
Article: SCIENTIFIC REPORTS. 2019;9(1):10762

Autophagy flux in critical illness, a translational approach.

Tardif N; Polia F; Tjäder I; Gustafsson T; Rooyackers O
Article: CLINICAL NUTRITION. 2018;37(4):1399-1405

Low serum selenium is associated with the severity of organ failure in critically ill children.

Broman M; Lindfors M; Norberg Å; Hebert C; Rooyackers O; Wernerman J; Fläring U
Article: CRITICAL CARE. 2018;22(1):152

Albumin mass balance and kinetics in liver transplantation.

Amouzandeh M; Nowak G; Januszkiewicz A; Wernerman J; Rooyackers O; Norberg Å
Article: CRITICAL CARE. 2018;22(1):13

An attenuated rate of leg muscle protein depletion and leg free amino acid efflux over time is seen in ICU long-stayers.

Gamrin-Gripenberg L; Sundström-Rehal M; Olsson D; Grip J; Wernerman J; Rooyackers O
Article: CRITICAL CARE. 2017;21(1):298

A supplemental intravenous amino acid infusion sustains a positive protein balance for 24 hours in critically ill patients.

Sundström Rehal M; Liebau F; Tjäder I; Norberg Å; Rooyackers O; Wernerman J
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2017;123(6):1501-1515

Influence of nutrient ingestion on amino acid transporters and protein synthesis in human skeletal muscle after sprint exercise.

Rundqvist HC; Esbjörnsson M; Rooyackers O; Österlund T; Moberg M; Apro W; Blomstrand E; Jansson E
Article: JOURNAL OF PARENTERAL AND ENTERAL NUTRITION. 2017;41(6):976-980

Approximation of Resting Energy Expenditure in Intensive Care Unit Patients Using the SenseWear Bracelet: A Comparison With Indirect Calorimetry.

Sundström M; Mehrabi M; Tjäder I; Rooyackers O; Hammarqvist F
Article: CLINICAL NUTRITION. 2017;36(2):429-437

Co-ingesting milk fat with micellar casein does not affect postprandial protein handling in healthy older men.

Gorissen SHM; Burd NA; Kramer IF; van Kranenburg J; Gijsen AP; Rooyackers O; van Loon LJC
Article: CLINICAL NUTRITION. 2017;36(1):186-190

Validation of a point-of-care instrument for bedside glutamine screening in the intensive care unit.

Pettersson L; Rydén S; Smedberg M; Tjäder I; Rooyackers O; Wernerman J
Article: PLOS ONE. 2017;12(3):e0174611

Repeated quantitative measurements of De Novo synthesis of albumin and fibrinogen.

Dumitrescu G; Komaromi A; Rooyackers O; Klaude M; Hebert C; Wernerman J; Norberg Å
Article: FRONTIERS IN ENDOCRINOLOGY. 2017;8:229

A Practical and Time-Efficient High-Intensity Interval Training Program Modifies Cardio-Metabolic Risk Factors in Adults with Risk Factors for Type II Diabetes.

Phillips BE; Kelly BM; Lilja M; Ponce-González JG; Brogan RJ; Morris DL; Gustafsson T; Kraus WE; Atherton PJ; Vollaard NBJ; Rooyackers O; Timmons JA
Article: INTENSIVE CARE MEDICINE EXPERIMENTAL. 2016;4(1):20

The effect of plasma from septic ICU patients on healthy rat muscle mitochondria.

Grip J; Jakobsson T; Tardif N; Rooyackers O
Article: CRITICAL CARE. 2016;20(1):370

Simultaneous assessment of the synthesis rate and transcapillary escape rate of albumin in inflammation and surgery.

Komáromi A; Estenberg U; Hammarqvist F; Rooyackers O; Wernerman J; Norberg Å
Journal article: INTENSIVE CARE MEDICINE EXPERIMENTAL. 2016;4(Suppl 1):30

ESICM LIVES 2016: part two

Sivakumar S; Taccone FS; Desai KA; Lazaridis C; Skarzynski M; Sekhon M; Henderson W; Griesdale D; Chapple L; Deane A; Williams L; Strickland R; Lange K; Heyland D; Chapman M; Rowland MJ; Garry P; Westbrook J; Corkill R; Antoniades CA; Pattinson KT; Fatania G; Strong AJ; Myers RB; Lazaridis C; Jermaine CM; Robertson CS; Rusin CG; Hofmeijer J; Sondag L; Tjepkema-Cloostermans MC; Beishuizen A; Bosch FH; van Putten MJAM; Carteron L; Patet C; Solari D; Oddo M; Ali MA; Dias C; Almeida R; Vaz-Ferreira A; Silva J; Monteiro E; Cerejo A; Rocha AP; Elsayed AA; Abougabal AM; Beshey BN; Alzahaby KM; Pozzebon S; Ortiz AB; Cristallini S; Lheureux O; Brasseur A; Vincent JL; Creteur J; Taccone FS; Hravnak M; Yousef K; Chang Y; Crago E; Friedlander RM; Abdelmonem SA; Tahon SA; Helmy TA; Meligy HS; Puig F; Dunn-Siegrist I; Pugin J; Gupta S; Govil D; Srinivasan S; Patel SJ; N JK; Gupta A; Tomar DS; Shafi M; Harne R; Arora DP; Talwar N; Mazumdar S; Papakrivou EE; Makris D; Manoulakas E; Tsolaki B; Karadodas B; Zakynthinos E; Garcia IP; Martin AD; Encinares VS; Ibañez MP; Montero JG; Labrador G; Cangueiro TC; Poulose V; Koh J; Kam JW; Yeter H; Kara A; Aktepe O; Topeli A; Tsolakoglou I; Intas G; Stergiannis P; Kolaros AA; Chalari E; Athanasiadou E; Martika A; Fildisis G; Faivre V; Mengelle C; Favier B; Payen D; Poppe A; Winkler MS; Mudersbach E; Schreiber J; Wruck ML; Schwedhelm E; Kluge S; Zöllner C; Tavladaki T; Spanaki AM; Dimitriou H; Kondili E; Choulaki C; Meleti E; Kafetzopoulos D; Georgopoulos D; Briassoulis G; la Torre AG-D; de la Torre-Prados MV; Tsvetanova-Spasova T; Nuevo-Ortega P; Rueda-Molina C; Fernández-Porcel A; Camara-Sola E; Salido-Díaz L; García-Alcántara A; Tavladaki T; Spanaki AM; Dimitriou H; Kondili E; Choulaki C; Meleti DE; Kafetzopoulos D; Georgopoulos D; Briassoulis G; Suberviola B; Riera J; Rellan L; Sanchez M; Robles JC; Lopez E; Vicente R; Miñambres E; Santibañez M; Le Guen M; Moore J; Mason N; Windpassinger M; Plattner O; Mascha E; Sessler DI; Research O; Melia U; 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Uya J; Corral L; Sedation an Delirium Group Hospital Universitari d; Elias-Jones I; Gemmell L; MacKay A; Randall D; Adwaney A; Blunden M; Prowle JR; Kirwan CJ; Thomas N; Martin A; Owen H; Darwin L; Conway D; Atkinson D; Sharman M; Moore J; Barbanti C; Amour J; Gaudard P; Rozec B; Mauriat P; M’rini M; Leger PL; Cambonie G; Liet JM; Girard C; Laroche S; Damas P; Assaf Z; Loron G; Lecourt L; Pouard P; Randall D; Adwaney A; Blunden M; Prowle JR; Kirwan CJ; Kim SH; Na S; Kim J; Oh SY; Jung CW; Yoo SH; Min SH; Chung EJ; Lee H; Lee NJ; Lee KW; Suh KS; Ryu HG; Marshall DC; Goodson RJ; Salciccioli JD; Shalhoub J; Potter EK; Kirk-Bayley J; Karanjia ND; Forni LG; Creagh-Brown BC; Bossy M; Nyman M; Tailor A; Creagh-Brown B; SPACeR group (Surrey Peri-operative, Anaesthesia a; D’Antini D; Spadaro S; Valentino F; Sollitto F; Cinnella G; Mirabella L; Calvo FJR; Bejarano N; Padilla D; Baladron V; Villajero P; Villazala R; Redondo J; Yuste AS; Liu J; Shen F; Teboul JL; Anguel N; Beurton A; Bezaz N; Richard C; Monnet X; Fossali T; Colombo R; Ottolina D; Rossetti M; Mazzucco C; Marchi A; Porta A; Catena E; Tollisen KH; Andersen GØ; Heyerdahl F; Jacobsen D; de Waard MC; Girbes ARJ; van IJzendoorn MCO; Buter H; Kingma WP; Navis GJ; Boerma EC; Rulisek J; Balik M; Zacharov S; Kim HS; Jeon SJ; Namgung H; Lee E; Lee E; Cho YJ; Lee YJ; Huang A; Cioccari L; Luethi N; Mårtensson J; Bellomo R; Forsberg M; Edman G; Höjer J; Forsberg S; Freile MTC; Hidalgo FN; Molina JAM; Lecumberri R; Rosselló AF; Travieso PM; Leon GT; Sanchez JG; Frias LS; Rosello DB; Verdejo JAG; Serrano JAN; Winterwerp D; van Galen T; Vazin A; Karimzade I; Zand A; Ozen E; Ekemen S; Akcan A; Sen E; Yelken BB; Kureshi N; Fenerty L; Thibault-Halman G; Erdogan M; Walling S; Green RS; Clarke DB; Briassoulis P; Kalimeris K; Ntzouvani A; Nomikos T; Papaparaskeva K; Politi E; Kostopanagiotou G; Crewdson K; Rehn M; Weaver A; Brohi K; Lockey D; Wright S; Thomas K; Baker C; Mansfield L; Stafford V; Wade C; Watson G; Bryant A; Chadwick T; Shen J; Wilkinson J; Furneval J; Henderson A; Hugill K; Howard P; Roy A; Bonner S; Baudouin S; Ramírez CS; Escalada SH; Viera MAH; Santana MC; Balcázar LC; Monroy NS; Campelo FA; Vázquez CFL; Santana PS; Santana SR; Carteron L; Patet C; Quintard H; Solari D; Bouzat P; Oddo M; Wollersheim T; Malleike J; Haas K; Carbon N; Schneider J; Birchmeier C; Fielitz J; Spuler S; Weber-Carstens S; Enseñat L; Pérez-Madrigal A; Saludes P; Proença L; Gruartmoner G; Espinal C; Mesquida J; Huber W; Eckmann M; Elkmann F; Gruber A; Lahmer T; Mayr U; Herner A; Schellnegger R; Schneider J; Schmid RM; Ayoub W; Samy W; Esmat A; Battah A; Mukhtar S; Mongkolpun W; Cortés DO; Cordeiro CPR; Vincent JL; Creteur J; Funcke S; Groesdonk H; Saugel B; Wagenpfeil G; Wagenpfeil S; Reuter DA; Fernandez MM; Fernandez R; Magret M; González-Castro A; Bouza MT; Ibañez M; García C; Balerdi B; Mas A; Arauzo V; Añón JM; Ruiz F; Ferreres J; Tomás R; Alabert M; Tizón AI; Altaba S; Llamas N; Goligher EC; Fan E; Herridge M; Vorona S; Sklar M; Dres M; Rittayamai N; Lanys A; Urrea C; Tomlinson G; Reid WD; Rubenfeld GD; Kavanagh BP; Brochard LJ; Ferguson ND; Neto AS; de Abreu MG; Pelosi P; Schultz MJ; for the PRoVENT investigators and the PROVE Networ; Guérin C; Papazian L; Reignier J; Ayzac L; Loundou A; Forel JM; Rolland-Debord C; Bureau C; Poitou T; Clavel M; Perbet S; Terzi N; Kouatchet A; Similowski T; Demoule A; Hunfeld N; Trogrlic Z; Ladage S; Osse RJ; Koch B; Rietdijk W; Devlin J; van der Jagt M; Picetti E; Ceccarelli P; Mensi F; Malchiodi L; Risolo S; Rossi I; Antonini MV; Servadei F; Caspani ML; Roquilly A; Lasocki S; Seguin P; Geeraerts T; Perrigault PF; Dahyot-Fizelier C; Paugam-Burtz C; Cook F; Cinotti R; dit Latte DD; Mahe PJ; Fortuit C; Feuillet F; Asehnoune K; Marzorati C; Spina S; Scaravilli V; Vargiolu A; Riva M; Giussani C; Sganzerla E; Citerio G; Barbadillo S; de Molina FJG; Álvarez-Lerma F; Rodríguez A; SEMICYUC/GETGAG Working Group; Zakharkina T; Martin-Loeches I; Matamoros S; Povoa P; Torres A; Kastelijn J; Hofstra JJ; de Jong M; Schultz M; Sterk P; Artigas A; Bos LJ; Moreau AS; Martin-Loeches I; Povoa P; Salluh J; Rodriguez A; Nseir S; TAVeM study group; de Jong E; van Oers JA; Beishuizen A; Girbes ARJ; Nijsten MWN; de Lange DW; Bonvicini D; Labate D; Benacchio L; Olivieri A; Pizzirani E; Lopez-Delgado JC; Gonzalez-Romero M; Fuentes-Mila V; Berbel-Franco D; Romera-Peregrina I; Martinez-Pascual A; Perez-Sanchez J; Abellan-Lencina R; Ávila-Espinoza RE; Moreno-Gonzalez G; Sbraga F; Griffiths S; Grocott MPW; Creagh-Brown B; POPC-CB investigators; Doyle J; Wilkerson P; Soon Y; Huddart S; Dickinson M; Riga A; Zuleika A; Miyamoto K; Kawazoe Y; Morimoto T; Yamamoto T; Fuke A; Hashimoto A; Koami H; Beppu S; Katayama Y; Ito M; Ohta Y; Yamamura H; DESIRE (DExmedetomidine for Sepsis in ICU Randomiz; Rygård SL; Holst LB; Wetterslev J; Johansson PI; Perner A; Soliman IW; de Lange DW; van Dijk D; van Delden JJM; Cremer OL; Slooter AJC; Peelen LM; McWilliams D; Snelson C; Neves AD; Loudet CI; Busico M; Vazquez D; Villalba D; Veronesi M; Lischinsky A; López FJL; Mori LB; Plotnikow G; Díaz A; Giannasi S; Hernandez R; Krzisnik L; Cecotti C; Viola L; Lopez R; Sottile JP; Benavent G; Estenssoro E; Chen CM; Lai CC; Cheng KC; Chou W; Chan KS; Roeker LE; Horkan CM; Gibbons FK; Christopher KB; Weijs PJM; Mogensen KM; Rawn JD; Robinson MK; Christopher KB; Tang Z; Qiu C; Ouyang B; Cai C; Guan X; Regueira T; Cea L; Carlos SJ; Elisa B; Puebla C; Vargas A; Poulsen MK; Thomsen LP; Kjærgaard S; Rees SE; Karbing DS; Wollersheim T; Frank S; Müller MC; Carbon NM; Skrypnikov V; Pickerodt PA; Falk R; Mahlau A; Weber-Carstens S; Lee A; Inglis R; Morgan R; Barker G; Kamata K; Abe T; Saitoh D; Tokuda Y; Green RS; Butler MB; Erdogan M; Hwa HT; Gil LJ; Vaquero RH; Rodriguez-Ruiz E; Lago AL; Allut JLG; Gestal AE; Gonzalez MAG; Thomas-Rüddel DO; Schwarzkopf D; Fleischmann C; Reinhart K; Suwanpasu S; Sattayasomboon Y; Filho NMF; Oliveira JCA; Ballalai CS; De Lucia CV; Araponga GP; Veiga LN; Silva CS; Garrido ME; Ramos BB; Ricaldi EF; Gomes SS; GEMINI; Gemmell L; MacKay A; Wright C; Docking RI; Doherty P; Black E; Stenhouse P; Plummer MP; Finnis ME; Phillips LK; Kar P; Bihari S; Biradar V; Moodie S; Horowitz M; Shaw JE; Deane AM; Yatabe T; Inoue S; Sakaguchi M; Egi M; Abdelhamid YA; Plummer MP; Finnis ME; Phillips LK; Kar P; Bihari S; Biradar V; Moodie S; Horowitz M; Shaw JE; Deane AM; Hokka M; Egi M; Mizobuchi S; Kar P; Plummer M; Abdelhamid YA; Giersch E; Summers M; Hatzinikolas S; Heller S; Chapman M; Jones K; Horowitz M; Deane A; Schweizer R; Jacquet-Lagreze M; Portran P; Junot S; Allaouchiche B; Fellahi JL; Guerci P; Ergin B; Kapucu A; Ince C; Cioccari L; Luethi N; Crisman M; Bellomo R; Mårtensson J; Shinotsuka CR; Fagnoul D; Brasseur A; Orbegozo D; Vincent JL; Preiser JC; Preiser JC; Lheureux O; Thooft A; Brimioulle S; Vincent JL; Iwasaka H; Tahara S; Nagamine M; Ichigatani A; Cabrera AR; Zepeda EM; Granillo JF; Sánchez JSA; Montoya AAT; Montenegro AP; Blanco GAG; Robles CMC; Drolz A; Horvatits T; Roedl K; Rutter K; Kluge S; Funk GC; Schneeweiss B; Fuhrmann V; Sabetian G; Pooresmaeel F; Zand F; Ghaffaripour S; Farbod A; Tabei H; Taheri L; Anandanadesan R; Metaxa V; Teixeira C; Pereira SM; Hernández-Marrero P; Carvalho AS; Beckmann M; Hartog CS; Schwarzkopf D; Raadts A; Robertsen A; Førde R; Skaga NO; Helseth E; Honeybul S; Ho K; Lopez PM; Gonzalez MN; Ortega PN; Sola EC; Spasova T; de la Torre-Prados MV; Kopecky O; Rusinova K; Waldauf P; Cepeplikova Z; Balik M; Domínguez JP; Almudevar PM; Carmona SA; Muñoz JJR; Castañeda DP; Abellán AN; Villamizar PR; Ramos JV; Pérez LP; Lucendo AP; Ejarque MC; Estella A; Camps VL; Martín MC; Masnou N; Bioethics work group of SEMICYUC; Barbosa S; Varela A; Palma I; Cristina L; Nunes E; Pereira I; Campello G; Granja C; Pande R; Pandey M; Varghese S; Chanu M; Van Dam MJ; Ter Braak EWMT; Estella A; Gracia M; Viciana R; Recuerda M; Fontaiña LP; Tharmalingam B; Kovari F; Rose L; Mcginlay M; Amin R; Burns K; Connolly B; Hart N; Jouvet P; Katz S; Leasa D; Mawdsley C; Mcauley D; Schultz M; Blackwood B; Denham S; Worrall R; Arshad M; Isherwood P; Khadjibaev A; Sabirov D; Rosstalnaya A; Parpibaev F; Sharipova V; Blanco GAG; Guzman CIO; Sánchez JSA; Granillo JF; Gupta S; Govil D; Srinivasan S; Patel SJ; N JK; Gupta A; Shafi M; Tomar DS; Harne R; Arora DP; Talwar N; Mazumdar S; Cha YS; Lee SJ; Tyagi N; Rajput RK; Taneja S; Singh VK; Sharma SC; Mittal S; Rao BK; Ayachi J; Fraj N; Romdhani S; Khedher A; Meddeb K; Sma N; Azouzi A; Bouneb R; Chouchene I; El Ghardallou M; Boussarsar M; Jennings R; Walter E; Ribeiro JM; Moniz I; Marçal R; Santos AC; Candeias C; e Silva ZC; Gomez SEZ; Nieto ORP; Gonzalez JAC; Cuellar AIV; Mildh H; Pettilä V; Korhonen AM; Karlsson S; Ala-Kokko T; Reinikainen M; Vaara ST; The FINNAKI Study Group; Zaleska-Kociecka M; Grabowski M; Dąbrowski M; Wozniak S; Piotrowska K; Banaszewski M; Imiela J; Stepinska J; Pérez AG; Ordoñez PF; Giribet A; Cuervo MAA; Cuervo RA; Esteban MAR; Fraile LI; Mittelbrum CP; Albaiceta GM; Koeze J; Keus F; Dieperink W; van der Horst ICC; van Meurs M; Zijlstra JG; Roberts S; Caballero CH; Isgro G; Hall D; Beitland S; Trøseid A-MS; Brusletto BS; Waldum-Grevbo BE; Berg JP; Sunde K; Huertas DG; Manzano F; Quintana MMJ; Osuna A; Santiago-Ruiz F; Rodríguez-Mejías C; Wangensteen R; Jamaati HR; Masjedi M; Zand F; Hashemian SMR; Sabetian G; Abbasi G; Khaloo V; Tabei SHA; Kafilzadeh A; Bakhodaei HH; Diaz JA; Silva R; Garcia DJ; Luis E; Gomez MN; Soriano R; Gonzalez PL; Ibrahim IA; Rafik MM; Al-Ansary AM; Algendi MA; Ali AA; Fuhrmann V; Roedl K; Horvatits T; Drolz A; Rutter K; Benten D; Kluwe J; Siedler S; Kluge S; Adedugbe I; Bird GT; Queen Square Neuroanaesthesia and Neurocritical Ca; Kennedy RM; Sharma S; Butler MB; Yugi G; Haroon BA; Witter T; Khaliq W; Singer M; Havaldar AA; Krishna B; Sriram S; Espinoza EDV; Pozo MO; Edul VSK; Furche M; Motta MF; Vazquez AR; Birri PNR; Ince C; Dubin A; Dogliotti A; Ramos A; Lovesio C; Delile E; Nevière R; Thiébaut P-A; Maupoint J; Mulder P; Coquerel D; Renet S; do Rego JC; Rieusset J; Richard V; Tamion F; Khaliq W; Andreis DT; Singer M; Smit B; Smulders YM; de Waard MC; van Straaten HMO; Girbes ARJ; Eringa EC; Man AMES-D; Alegría L; Soto D; Luengo C; Gomez J; Jarufe N; Bruhn A; Castro R; Kattan E; Tapia P; Rebolledo R; Achurra P; Ospina-Tascón G; Bakker J; Hernández G; Bertini P; Guarracino F; Baldassarri R; Pinsky MR; Alegría L; Vera M; Dreyse J; Carpio D; Henriquez C; Gajardo D; Bravo S; Castro R; Ospina-Tascón G; Bakker J; Hernández G; Kim S; Lee M; Park SY; So S; Lee H; Kačar MB; Kačar SM; Uddin I; Belhaj AM; Aydın MA; Avsec D; Kapuağası A; Kaymak Ç; Kovach L; Şencan İ; Meço B; Özçelik M; Ünal N; Lazaridis C; Jenni-Moser B; Jeitziner M-M; Galassi MS; Sales FL; de Moraes KCL; Batista CL; Júnior JADS; Marcari TB; Lobato R; Castro CSAA; de Souza LM; Rodrigues FFP; Correa NG; Pelegrini AM; Eid RAC; Timenetsky KT; Cazati D; Lobato M; Diniz PS; Rocha LL; Cavalheiro AM; Lucinio NM; Santos ER; Norrenberg M; Gleize A; Preiser JC; Simón IF; Carmona SA; Valhonrat IL; Domínguez JP; Abellán AN; Almudévar PM; Dávila F; Rubio JJ; Ramos AJ; Reina ÁJR; López NP; Pérez MA; Apolo DXC; Villén LM; López FMP; García IP; Izurieta JRN; Guerrero JJE; Renal Transplantation HUVR; Calvert S; Quint M; Adeniji K; Young R; Shevill DD; Robertson E; Garside P; Walter E; Isotti P; De Vecchi MM; Perduca AE; Negro A; Villa G; Manara DF; Cabrini L; Zangrillo A; Frencken JF; van Baal L; Peelen LM; Donker DW; Horn J; van der Poll T; van Klei WA; Bonten MJM; Cremer OL; Menard CE; Kumar A; Rimmer E; Doucette S; Turgeon AF; Houston BL; Houston DS; Zarychanski R; Pinto BB; Carrara M; Ferrario M; Bendjelid K; Nunes J; Diaz P; Silva G; Escórcio S; Chaves S; Jardim M; Fernandes N; Câmara M; Duarte R; Pereira CA; Vieira J; Nóbrega JJ; Robles CMC; de Oca-Sandoval MAM; Sánchez-Rodríguez A; Joya-Galeana JG; Correa-Morales A; Camarena-Alejo G; Aguirre-Sánchez J; Franco-Granillo J; Soliman M; Al Azab A; El Hossainy R; Nagy H; Nirmalan M; Crippa IA; Cavicchi FZ; Vincent JL; Creteur J; Taccone FS; Chaari A; Hakim KA; Hassanein H; Etman M; El Bahr M; Bousselmi K; Khalil ES; Kauts V; Casey WF; Imahase H; Sakamoto Y; Inoue S; Yamada KC; Koami H; Miike T; Nagashima F; Iwamura T; Boscolo A; Lucchetta V; Piasentini E; Bertini D; Manesso L; Spiezia L; Simioni P; Ori C; Souza RB; Martins AM; Liberatore AMA; Kang YR; Nakamae MN; Vieira JCF; Koh IHJ; Hanslin K; Wilske F; Skorup P; Sjölin J; Lipcsey M; Long WJ; Zhen CE; Vakalos A; Avramidis V; Wu SH; Shyu LJ; Li CH; Yu CH; Chen HC; Wang CH; Lin KH; Aray ZE; Gómez CF; Tejero AP; Monge DD; Losada VM; Tarancón CM; Cortés SD; Gutiérrez AM; Álvarez TP; Rouze A; Jaffal K; Six S; Stolz K; Cattoen V; Nseir S; Arnal JM; Saoli M; Novotni D; Garnero A; Becher T; Buchholz V; Schädler D; Frerichs I; Weiler N; Eronia N; Mauri T; Gatti S; Maffezzini E; Bronco A; Alban L; Sasso T; Marenghi C; Grasselli G; Pesenti A; Bellani G; Al-Fares A; Del Sorbo L; Anwar S; Facchin F; Azad S; Zamel R; Ferguson N; Cypel M; Keshavjee S; Fan E; Durlinger E; Spoelstra-de Man A; Smit B; de Grooth HJ; Girbes A; Straaten HO-V; Smulders Y; Alfaro MA; Parrilla F; Meli A; Pellegrini M; Rodriguez N; Goyeneche JM; Morán I; Aguirre H; Mancebo J; Heines SJH; Strauch U; Bergmans DCJJ; Blankman P; Shono A; Hasan D; Gommers D; Chung WY; Lee KS; Jung YJ; Park JH; Sheen SS; Park KJ; Worral R; Denham S; Isherwood P; Rees SE; Larraza S; Dey N; Spadaro S; Brohus JB; Winding RW; Volta CA; Karbing DS; Ampatzidou F; Vlachou A; Kehagioglou G; Karaiskos T; Madesis A; Mauromanolis C; Michail N; Drossos G; Saraj N; Rijkenberg S; Feijen HM; Endeman H; Donnelly AAJ; Morgan E; Garrard H; Buckley H; Russell L; Haase N; Perner A; Goh C; Mouyis K; Woodward CLN; Halliday J; Encina GB; Ros J; Lagunes L; Tabernero J; Bosch F; Rello J; Huertas DG; Manzano F; Morente-Constantin E; Rivera-Ginés B; Colmenero-Ruiz M; Abellán AN; Pérez LP; Lucendo AP; Almudévar PM; Domínguez JP; Villamizar PR; Sanz JG; Simon IF; Valbuena BL; Carmona SA; Pais M; Ramalingam S; Díaz C; Fox L; Santafe M; Barba P; García M; Leal S; Pérez M; Pérez MLP; Abellán AN; Lucendo AP; Almudevar PM; Domínguez JP; Villamizar PR; Veganzones J; Simón IF; Valbuena BL; Martínez N; Carmona SA; Moors I; Mokart D; Pène F; Lambert J; Kouatchet A; Mayaux J; Vincent F; Nyunga M; Bruneel F; Laisne L; Rabbat A; Lebert C; Perez P; Chaize M; Renault A; Meert AP; Hamidfar R; Jourdain M; Darmon M; Schlemmer B; Chevret S; Lemiale V; Azoulay E; Benoit D; Martins-Branco D; Sousa M; Marum S; Bouw MJ; Galstyan G; Makarova P; Parovichnikova E; Kuzmina L; Troitskaya V; Drize N; Gemdzhian E; Savchenko V; Chao HC; Kılıc E; Demiriz B; Uygur ML; Sürücü M; Cınar K; Yıldırım AE; Kiss K; Köves B; Csernus V; Molnár Z; Ntantana A; Matamis D; Savvidou S; Giannakou M; Gouva M; Nakos G; Koulouras V; Gaffney S; Black E; Docking R; Judge C; Drew T; Misran H; Munshi R; McGovern L; Coyle M; Dunne L; Deasy E; Lavin P; Fahy A; Darcy DM; Donnelly M; Ismail NH; Hall T; Wykes K; Jack J; Ngu WC; Morgan P; Ruiz-Ramos J; Ramirez P; Gordon M; Villarreal E; Frasquet J; Poveda-Andrés JL; Castellanos A; Ijssennagger CE; ten Hoorn S; van Wijk A; van den Broek JM; Tuinman PR; Elmenshawy AM; Hammond BD; Gibbon G; Belcham T; Burton K; Taniguchi LU; Ramos FJS; Momma AK; Martins-Filho APR; Bartocci JJ; Lopes MFD; Sad MH; Rodrigues CM; Pires EMC; Vieira JM; Leite MA; Murbach LD; Osaku EF; Barreto J; Duarte ST; Taba S; Miglioranza D; Gund DP; Lordani CF; Costa CRLM; Ogasawara SM; Jorge AC; Duarte PAD; Spadaro S; Capuzzo M; Corte FD; Terranova S; Scaramuzzo G; Fogagnolo A; Bertacchini S; Bellonzi A; Ragazzi R; Volta CA; Cruz C; Nunes A; Pereira FS; Aragão I; Cardoso AF; Santos C; Malheiro MJ; Castro H; Cardoso T; Paratz J; Kenardy J; Comans T; Coyer F; Thomas P; Boots R; Pereira N; Vilas-Boas A; Gomes E; Dias C; Torres J; Carvalho D; Molinos E; Vales C; Araújo R; Cruz C; Nunes A; Pereira FS; Cardoso AF; Santos C; Malheiro MJ; Castro H; Cardoso T; Karnatovskaia L; Philbrick K; Ognjen G; Clark M; Montero RM; Varas JL; Sánchez-Elvira LA; Delgado CP; Díaz PV; Ruiz BL; Guerrero AP; Galache JAC; Jiménez R; Rebollo S; Alejandro O; Fernández A; Moreno S; Herrera L; Ojados A; Galindo M; Murcia J; Contreras M; Sánchez-Argente S; Bonilla Y; Rodríguez MD; Allegue JM; Cakin Ö; Parlak H; Kirca H; Mutlu F; Aydınlı B; Cengiz M; Ramazanoglu A; Jung E-J; Oh S-Y; Lee H; Filho NMF; Ricaldi EF; Gomes SS; Ramos BB; De Lucia CV; Ballalai CS; Oliveira JCA; Araponga GP; Veiga LN; Silva CS; Garrido ME; GEMINI; Domenech JC; Montalvo AP; Chornet TC; Martinez PC; Ribas MP; Costa RG; Ortega AC; Forbes C; Prescott H; Lal A; Khan FA; Dela Pena EG; Dizon JS; Perez PPP; Wong CMJ; Garach MM; Romero OM; Puerta RR; Diaz FA; Bailon AMP; Pinel AC; Maldonado LP; Kalaiselvan MS; kumar RLS; Renuka MK; Kumar ASA; De Rosa S; Ferrari F; Checcacci SC; Rigobello A; Joannidis M; Politi F; Pellizzari A; Bonato R; Fernandez-Carmona A; Macias-Guarasa I; Gutierrez-Rodriguez R; Martinez-Lopez P; Diaz-Castellanos MA; EDISVAL Group; Fernandez-Carmona A; Arias-Diaz M; Aguilar-Alonso E; Macias-Guarasa I; Martinez-Lopez P; Diaz-Castellanos MA; EDISVAL Group; Nikandish RN; Artemenko V; Budnyuk A; Bassi GL; Senussi T; Idone F; Xiol EA; Travierso C; Chiurazzi C; Motos A; Amaro R; Hua Y; Fernández-Barat L; Ranzani OT; Bobi Q; Rigol M; Torres A; Youn A; Hwang JG; Garach MM; Romero OM; Ossorio MEY; Diaz FA; Bailon AMP; Pinel AC; Maldonado LP; Teixeira C; Figueira H; Oliveira R; Mota A; Aragão I; Kamp O; Cruciger O; Aach M; Kaczmarek C; Waydhas C; Schildhauer TA; Hamsen U; Camprubí-Rimblas M; Chimenti L; Guillamat-Prats R; Lebouvier T; Bringué J; Tijero J; Gómez MN; Blanch L; Artigas A; Tagliabue G; Ji M; Jagers JVS; Easton PA; Souza RB; Liberatore AMA; Martins AMCRPF; Vieira JCF; Kang YR; Nakamae MN; Koh IHJ; Hong JY; Shin MH; Park MS; Pomprapa A; Pickerodt PA; Hofferberth MBT; Russ M; Braun W; Walter M; Francis R; Lachmann B; Leonhardt S; Koh IHJ; Souza RB; Martins AMCRPF; Vieira JCF; Liberatore AMA; Landaverde-López A; Canedo-Castillo NA; Esquivel-Chávez A; Arvizu-Tachiquín PC; Sánchez-Hurtado LA; Baltazar-Torres JA; Cardoso V; Krystopchuk A; Castro S; Melão L; Firmino S; Marreiros A; Granja C; Almaziad S; Kubbara A; Barnett W; Nakity R; Alamoudi W; Altook R; Tarazi T; Fida M; Safi F; Assaly R; Santini A; Milesi M; Maraffi T; Pugni P; Andreis DT; Cavenago M; Gattinoni L; Protti A; Perchiazzi G; Borges JB; Bayat S; Porra L; Broche L; Pellegrini M; Scaramuzzo G; Hedenstierna G; Larsson A; Pellegrini M; Hedenstierna G; Roneus A; Segelsjö M; Vestito MC; Larsson A; Perchiazzi G; Gremo E; Nyberg A; Castegren M; Pikwer A; Yoshida T; Engelberts D; Otulakowski G; Katira B; Post M; Ferguson ND; Brochard L; Amato MBP; Kavanagh BP; PLUG Working group; Koch N; Huber W; Hoellthaler J; Mair S; Phillip V; Schmid RM; Beitz A; Baladrón V; Calvo FJR; Padilla D; Villarejo P; Villazala R; Yuste AS; Bejarano N; Steenstra RJ; Banierink H; Hof J; van der Horst IC; Nijsten MW; Hoekstra M; Roedl K; Sterz F; Horvatits T; Horvatits K; Drolz A; Herkner H; Fuhrmann V; Kott M; Zitta K; Brandt B; Schildhauer C; Elke G; Hummitzsch L; Frerichs I; Weiler N; Albrecht M; González LR; Alonso DC; Ortiz AB; Sánchez RDP; Lucas JH; Roedl K; Sterz F; Drolz A; Horvatits K; Horvatits T; Herkner H; Fuhrmann V; Horvatits T; Drolz A; Roedl K; Rutter K; Ferlitsch A; Fauler G; Trauner M; Fuhrmann V; Horvatits T; Pischke S; Fischer L; Thaiss F; Koch M; Bangert K; Fuhrmann V; Kluge S; Lohse AW; Nashan B; Sterneck M; Faenza S; Siniscalchi A; Pierucci E; Mancini E; Ricci D; Gemelli C; Cuoghi A; Magnani S; Atti M; Sotos F; Cánovas J; López A; Burruezo A; Torres D; Herrera-Gutierrez ME; Barrueco-Francioni J; Arias-Verdú D; Lozano-Saez R; Quesada-Garcia G; Seller-Pérez G; Figueiredo A; Anzola Y; Pereira R; Bento L; Arias-Verdú D; Lai M; Deiana M; Barrueco-Francioni J; Herrera-Gutierrez ME; Seller-Perez G; Vardas K; Ilia S; Sertedaki A; Charmadari E; Stratakis CA; Briassouli E; Goukos D; Psarra K; Botoula E; Tsagarakis S; Mageira E; Routsi C; Nanas S; Briassoulis G; Boscolo A; Bertini D; Campello E; Lucchetta V; Piasentini E; Radu CM; Manesso L; Simioni P; Ori C; Su H; Lam YM; Willis K; Pullar V; Hubner RP; Tsang JL; de Guadiana-Romualdo LG; Rebollo-Acebes S; Esteban-Torrella P; Jiménez-Sánchez R; Jiménez-Santos E; Ortín-Freire A; Hernando-Holgado A; Albaladejo-Otón MD; Coelho L; Rabello L; Salluh J; Martin-Loeches I; Rodriguez A; Nseir S; Póvoa P; TAVeM study Group; Varis E; Pettilä V; Poukkanen M; Jacob S; Karlsson S; Perner A; Takala J; Wilkman E; The FINNAKI Study Group; Lundberg OHM; Bergenzaun L; Rydén J; Rosenqvist M; Melander O; Chew MS; Rodriguez-Ruiz E; Vaquero RH; Lago AL; Allut JLG; Gestal AE; Gonzalez MAG; Kishihara Y; Yasuda H; Rebollo S; de Guadiana-Romualdo LG; Jimenez R; Torrella PE; Fernandez A; Sanchez S; Ortin A; Bassi GL; Prats RG; Artigas A; Aguilera E; Marti D; Ranzani OT; Rigol M; Fernandez L; Ferrer M; Martin-Loeches I; Torres A; Lanziotti VS; Póvoa P; Pulcheri L; Ribeiro MO; Barbosa AP; e Silva JRL; Soares M; Salluh JIF; Garcia IP; Martin AD; Marqués MG; Moreno AP; Pizarraya AG; Diaz JP; Ibañez MP; Smani Y; Connell MM; Zhang LA; Parker RS; Banerjee I; Clermont G; Norberg E; Oras J; Cuisinier A; Maufrais C; Payen JF; Nottin S; Walther G; Bouzat P; Arib S; Bilotta F; Badenes R; Rubulotta F; Mirek S; Crippa IA; Monfort B; Stazi E; Roig AL; Creteur J; Taccone FS; Magnoni S; Marando M; Pifferi S; Conte V; Ortolano F; Carbonara M; Bertani G; Scola E; Cadioli M; Triulzi F; Colombo A; Stocchetti N; Rotzel HB; Lázaro AS; Prada DA; Guimillo MR; Piqueras CS; Guia JR; Simon MG; Arizmendi AM; Carratalá A; El Maraghi S; Yehia A; Bakry M; Shoman A; Backes FN; Bianchin MM; Vieira SRR; de Souza A; Backes AN; Klein C; Kalaiselvan MS; Renuka MK; Arunkumar AS; Lozano A; Lheureux O; Badenes R; Vincent JL; Creteur J; Taccone FS; Gallaher C; Cattlin S; Gordon S; Picard J; Fontana V; Bond O; Nobile L; Vincent JL; Creteur J; Taccone FS; Mrozek S; Delamarre L; Capilla F; Al-Saati T; Fourcade O; Geeraerts T; Dominguez-Berrot AM; Gonzalez-Vaquero M; Vallejo-Pascual ME; Gupta D; Ivory BD; Chopra M; McCarthy J; Felderhof CL; MacNeil C; Rubulotta F; Waldauf P; Maggiorini M; Duska F; on behalf of Department of Professional Developmen; Fumis RRL; Junior JMV; Amarante G; Skorko A; Sanders S; Aron J; Kroll RJ; Redfearn C; Krishnan P; Khalil JE; Kovari F; Kongpolprom N; Gulia V; Lourenço E; Melão L; Duro C; Baptista G; Alves A; Arminda B; Rodrigues M; Marreiros A; Granja C; Hayward J; Baldwin F; Gray R; Katinakis PA; Stijf M; Ten Kleij M; Jansen-Frederiks M; Broek R; de Bruijne M; Spronk PE; Sinha K; Luney M; Palmer K; Keating L; Abu-Habsa M; Bahl R; Baskaralingam N; Ahmad A; Kanapeckaite L; Bhatti P; Glace S; Jeyabraba S; Lewis HF; Kostopoulos A; Raja M; West A; Ely A; Turkoglu LM; Zolfaghari P; Baptista JP; Marques MP; Martins P; Pimentel J; Gupta D; Su YC; Villacres S; Stone ME; Parsikia A; Medar S; O’Dea KP; Porter J; Tirlapur N; Jonathan JM; Singh S; Takata M; Critical Care Research Group; Abu-Habsa M; Ahmad A; McWhirter E; Lyon R; Hariz ML; Azmi E; Alkhan J; Honeybul S; Movsisyan V; Petrikov S; Marutyan Z; Aliev I; Evdokimov A; Antonucci E; Merz T; Hartmann C; Pelosi P; Calzia E; Radermacher P; Nußbaum B; Hartmann C; Huber-Lang M; Gröger M; Radermacher P; Nußbaum B; Nußbaum B; Antonucci E; Calzia E; Pelosi P; Radermacher P; Hartmann C; Svoren-Jabalera E; Davenport EE; Humburg P; Knight J; Hinds CJ; Jun IJ; Kim WJ; Lee EH; Besch G; Perrotti A; Puyraveau M; Carteron L; Baltres M; Samain E; Chocron S; Pili-Floury S; Plata-Menchaca EP; Sabater-Riera J; Estruch M; Boza E; Sbraga F; Toscana-Fernández J; Bruguera-Pellicer E; Ordoñez-Llanos J; Pérez-Fernández XL; SIRAKI group; Cavaleiro P; Tralhão A; Arrigo M; Lopes J-P; Lebrun M; Cholley B; PerezVela JL; MarinMateos H; Rivera JJJ; Llorente MAA; De Marcos BG; Fernandez FJG; Laborda CG; Zamora DF; Grupo ESBAGA; Delgado JCL; Imperiali C; Berbel-Franco D; Dastis M; Moreno-Gonzalez G; Perez-Sanchez J; Romera-Peregrina I; Abellan-Lencina R; Martinez-Pascual A; Fuentes-Mila V; Gonzalez-Romero M; Górka J; Górka K; Iwaniec T; Frołow M; Polok K; Fronczek J; Kózka M; Musiał J; Szczeklik W; Pérez AG; Ordoñez PF; Giribet A; Cuervo MAA; Cuervo RA; Esteban MAR; Fraile LI; Mittelbrum CP; Albaiceta GM; Ampatzidou F; Sileli M; Kehagioglou G; Madesis A; Karaiskos T; Moursia C; Maleoglou H; Leleki K; Drossos G; Uz Z; Ince Y; Papatella R; Bulent E; Guerci P; Ince C; De Mol B; Vicka V; Gineityte D; Ringaitiene D; Norkiene I; Sipylaite J; Möller C; Fleischmann C; Thomas-Rueddel DO; Vlasakov V; Rochwerg B; Theurer P; Gattinoni L; Reinhart K; Hartog CS; Pérez AG; Al Sibai JZ; Camblor PM; Fernandez PA; Gala JMG; Guisasola JS; Albaiceta GM; Tamura T; Yatabe T; Miyajima I; Yamashita K; Yokoyama M; Ampatzidou F; Kehagioglou G; Dalampini E; Nastou M; Baddour A; Ignatiadis A; Asteri T; Drossos G; Hathorn KE; Purtle SW; Horkan CM; Gibbons FK; Christopher KB; Viana MV; Tonietto TA; Gross LA; Costa VL; Tavares ALJ; Lisboa BO; Moraes RB; Vieira SR; Viana LV; Azevedo MJ; Ceniccola GD; Pequeno RSF; Holanda TP; Mendonça VS; Araújo WMC; Carvalho LSF; Segaran E; Vickers L; Brinchmann K; Wignall I; Rubulotta F; De Brito-Ashurst I; del Olmo R; Esteban MJ; Vaquerizo C; Carreño R; Gálvez V; Kaminsky G; Nieto B; Fuentes M; De la Torre MA; Torres E; Alonso A; Velayos C; Saldaña T; Escribá A; GRIP J; Kölegård R; Sundblad P; Rooyackers O; Naser B; Jaziri F; Jazia AB; Barghouth M; Hentati O; Skouri W; El Euch M; Mahfoudhi M; Turki S; Abdelghni KB; Abdallah B; Maha BNM; Cánovas J; Sotos F; López A; Lorente M; Burruezo A; Torres D; Polok K; Włudarczyk A; Górka J; Hałek A; Musiał J; Szczeklik W; Jazia AB; Jaziri F; Bargouth M; Bennasr M; Turki S; Abdelghani KB; Abdallah TB; de Grooth HJ; Geenen IL; Parienti JJ; Straaten HMO-V; Shum HP; King HS; Chan KC; Yan WW; Londoño JG; Cardenas CL; Pedrosa MM; Gubianas CM; Bertolin CF; Batllori NV; Sirvent JM; Wykes K; Jack J; Morgan P; Mukhopadhyay A; Chan HY; Kowitlawakul Y; Remani D; Leong CSF; Henry CJ; Puthucheary ZA; Mendsaikhan N; Begzjav T; Lundeg G; Dünser M; Espinoza EDV; Welsh SP; Motta MF; Guerra E; Zerpa MCL; Zechner F; Furche M; Berdaguer F; Birri PNR; Risso-Vazquez A; Dubin A; Masevicius FD; Greaney D; Magee A; Fitzpatrick G; Lugo-Cob RG; Sánchez-Hurtado LA; Arvizu-Tachiquín PC; Tejeda-Huezo BC; Cano-Oviedo AA; Baltazar-Torres JA; Aydogan MS; Togal T; Taha A; Chai HZ; Kam C; Razali SSY; Sivasamy V; Kuan LY; Poulose V; Morales MAL; Castro S; Pires T; Melão L; Krystopchuk A; Pereira I; Granja C; Taniguchi LU; Pires EMC; Vieira JM; Azevedo LCP
Article: OBESITY SURGERY. 2016;26(7):1391-1397

Improved Muscle Mitochondrial Capacity Following Gastric Bypass Surgery in Obese Subjects.

Fernström M; Bakkman L; Loogna P; Rooyackers O; Svensson M; Jakobsson T; Brandt L; Lagerros YT
Article: CRITICAL CARE. 2016;20(1):113

Leakage of albumin in major abdominal surgery.

Norberg Å; Rooyackers O; Segersvärd R; Wernerman J
Article: CRITICAL CARE. 2016;20:54

Measuring energy expenditure in the intensive care unit: a comparison of indirect calorimetry by E-sCOVX and Quark RMR with Deltatrac II in mechanically ventilated critically ill patients.

Rehal MS; Fiskaare E; Tjäder I; Norberg Å; Rooyackers O; Wernerman J
Article: PLOS ONE. 2016;11(3):e0150440

Plasma Glutamine Concentrations in Liver Failure.

Helling G; Wahlin S; Smedberg M; Pettersson L; Tjäder I; Norberg Å; Rooyackers O; Wernerman J
Journal article: INTENSIVE CARE MEDICINE EXPERIMENTAL. 2015;3(Suppl 1):a623

The effect of plasma from septic icu patients on healthy rat muscle mitochondria

Grip J; Jacobsson T; Tardif N; Rooyackers O
Journal article: INTENSIVE CARE MEDICINE EXPERIMENTAL. 2015;3(Suppl 1):a190

Validation of a point-of-care instrument for bedside glutamine screening in the intensive care unit

Pettersson L; Ryden S; Tjäder I; Rooyackers O; Wernerman J
Journal article: INTENSIVE CARE MEDICINE EXPERIMENTAL. 2015;3(Suppl 1):a179

Synthesis rates of myosin and actin in skeletal muscle of critically ill patients

Tjäder I; Klaude M; Hssain A; Guillet C; Wernerman J; Rooyackers O
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2015;59(10):1311-1318

Whole blood glutathione status and ICU morbidity in critically ill children.

Fläring U; Ekmark L; Wernerman J; Rooyackers O
Article: FASEB JOURNAL. 2015;29(10):4358-4373

Leucine does not affect mechanistic target of rapamycin complex 1 assembly but is required for maximal ribosomal protein s6 kinase 1 activity in human skeletal muscle following resistance exercise.

Apró W; Moberg M; Hamilton DL; Ekblom B; Rooyackers O; Holmberg H-C; Blomstrand E
Article: CLINICAL SCIENCE. 2015;129(4):375-384

Lactate kinetics and mitochondrial respiration in skeletal muscle of healthy humans under influence of adrenaline.

Grip J; Jakobsson T; Hebert C; Klaude M; Sandström G; Wernerman J; Rooyackers O
Article: BRITISH JOURNAL OF SURGERY. 2015;102(7):767-775

Protein kinetics in human endotoxaemia and their temporal relation to metabolic, endocrine and proinflammatory cytokine responses.

Khan ASA; Gibson JM; Carlson GL; Rooyackers O; New JP; Soop M
Article: CRITICAL CARE. 2015;19(1):106

Short-term amino acid infusion improves protein balance in critically ill patients.

Liebau F; Sundström M; van Loon LJC; Wernerman J; Rooyackers O
Article: AMINO ACIDS. 2015;47(3):535-542

Plasma glutamine deficiency is associated with multiple organ failure in critically ill children.

Ekmark L; Rooyackers O; Wernerman J; Fläring U
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2015;101(3):549-557

Effect of initiating enteral protein feeding on whole-body protein turnover in critically ill patients.

Liebau F; Wernerman J; van Loon LJC; Rooyackers O
Article: CLINICAL NUTRITION. 2015;34(1):95-100

Whole body protein turnover in critically ill patients with multiple organ failure.

Rooyackers O; Kouchek-Zadeh R; Tjäder I; Norberg Å; Klaude M; Wernerman J
Article: PLOS ONE. 2015;10(8):e0136371

Albumin Kinetics in Patients Undergoing Major Abdominal Surgery.

Norberg Å; Rooyackers O; Segersvärd R; Wernerman J
Article: CRITICAL CARE. 2014;18(6):677

Plasma glutamine concentration after intensive care unit discharge: an observational study.

Smedberg M; Grass JN; Pettersson L; Norberg Å; Rooyackers O; Wernerman J
Article: CLINICAL NUTRITION. 2014;33(5):802-807

Upper-body obese women are resistant to postprandial stimulation of protein synthesis.

Liebau F; Jensen MD; Nair KS; Rooyackers O
Article: PEDIATRIC CRITICAL CARE MEDICINE. 2014;15(4):314-328

Amino acid concentrations in critically ill children following cardiac surgery*.

Gielen M; Vanhorebeek I; Wouters PJ; Mesotten D; Wernerman J; Van den Berghe G; Rooyackers O
Article: CRITICAL CARE. 2014;18(2):R72

Endogenous glutamine production in critically ill patients: the effect of exogenous glutamine supplementation.

Mori M; Rooyackers O; Smedberg M; Tjäder I; Norberg A; Wernerman J
Article: PLOS ONE. 2014;9(5):e96601

A tracer bolus method for investigating glutamine kinetics in humans.

Mori M; Smedberg M; Klaude M; Tjäder I; Norberg A; Rooyackers O; Wernerman J
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2013;98(6):1485-1492

Autophagic-lysosomal pathway is the main proteolytic system modified in the skeletal muscle of esophageal cancer patients.

Tardif N; Klaude M; Lundell L; Thorell A; Rooyackers O
Article: PHYSIOLOGICAL REPORTS. 2013;1(5):e00076

Nutrient ingestion increased mTOR signaling, but not hVps34 activity in human skeletal muscle after sprint exercise.

Rundqvist HC; Lilja MR; Rooyackers O; Odrzywol K; Murray JT; Esbjörnsson M; Jansson E
Article: CRITICAL CARE. 2013;17(4):R158

Whole body protein kinetics during hypocaloric and normocaloric feeding in critically ill patients.

Berg A; Rooyackers O; Bellander B-M; Wernerman J
Article: CRITICAL CARE. 2013;17(3):R87

Continuous on-line glucose measurement by microdialysis in a central vein. A pilot study.

Blixt C; Rooyackers O; Isaksson B; Wernerman J
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2013;57(2):214-219

Continuous glucose monitoring by intravenous microdialysis: influence of membrane length and dialysis flow rate.

Rooyackers O; Blixt C; Mattsson P; Wernerman J
Article: CLINICAL NUTRITION. 2012;31(5):676-681

The effect of perioperative glucose control on postoperative insulin resistance.

Blixt C; Ahlstedt C; Ljungqvist O; Isaksson B; Kalman S; Rooyackers O
Article: JOURNAL OF PARENTERAL AND ENTERAL NUTRITION. 2012;36(5):556-561

Pharmacologically dosed oral glutamine reduces myocardial injury in patients undergoing cardiac surgery: a randomized pilot feasibility trial.

Sufit A; Weitzel LB; Hamiel C; Queensland K; Dauber I; Rooyackers O; Wischmeyer PE
Article: ACTA PHYSIOLOGICA. 2012;205(3):411-422

Sprint exercise enhances skeletal muscle p70S6k phosphorylation and more so in women than in men.

Esbjörnsson M; Rundqvist HC; Mascher H; Österlund T; Rooyackers O; Blomstrand E; Jansson E
Article: SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS. 2012;22(3):399-409

Reduction in plasma leucine after sprint exercise is greater in males than in females.

Esbjörnsson M; Rooyackers O; Norman B; Rundqvist HC; Nowak J; Bülow J; Simonsen L; Jansson E
Article: CLINICAL SCIENCE. 2012;122(12):591-597

Glutamine and glutathione at ICU admission in relation to outcome.

Rodas PC; Rooyackers O; Hebert C; Norberg Å; Wernerman J
Article: BRITISH JOURNAL OF ANAESTHESIA. 2012;108(2):254-261

Gut microcirculatory and mitochondrial effects of hyperdynamic endotoxaemic shock and norepinephrine treatment.

Andersson A; Rundgren M; Kalman S; Rooyackers O; Brattstrom O; Oldner A; Eriksson S; Frithiof R
Article: CLINICAL SCIENCE. 2012;122(3):133-142

Protein metabolism and gene expression in skeletal muscle of critically ill patients with sepsis.

Klaude M; Mori M; Tjäder I; Gustafsson T; Wernerman J; Rooyackers O
Article: ACTA PHYSIOLOGICA. 2011;202(2):175-184

Enhanced rates of muscle protein synthesis and elevated mTOR signalling following endurance exercise in human subjects.

Mascher H; Ekblom B; Rooyackers O; Blomstrand E
Article: OBESITY FACTS. 2010;3(6):371-375

Reduced respiratory capacity in muscle mitochondria of obese subjects.

Bakkman L; Fernström M; Loogna P; Rooyackers O; Brandt L; Lagerros YT
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2010;54(7):841-847

Continuous glucose monitoring by intravenous microdialysis.

Rooyackers O; Blixt C; Mattsson P; Wernerman J
Article: GENOME MEDICINE. 2010;2(1):1

Using transcriptomics to identify and validate novel biomarkers of human skeletal muscle cancer cachexia.

Stephens NA; Gallagher IJ; Rooyackers O; Skipworth RJ; Tan BH; Marstrand T; Ross JA; Guttridge DC; Lundell L; Fearon KC; Timmons JA
Article: CLINICAL SCIENCE. 2009;118(6):421-427

Protein metabolism in leg muscle following an endotoxin injection in healthy volunteers.

Vesali RF; Cibicek N; Jakobsson T; Klaude M; Wernerman J; Rooyackers O
Article: JOURNAL OF LIPID RESEARCH. 2009;50(11):2258-2264

Marked upregulation of cholesterol 25-hydroxylase expression by lipopolysaccharide.

Diczfalusy U; Olofsson KE; Carlsson A-M; Gong M; Golenbock DT; Rooyackers O; Fläring U; Björkbacka H
Article: CLINICAL SCIENCE. 2009;117(9):339-344

Glutathione and amino acid concentrations in human liver during short warm ischaemia and reperfusion: a pilot study.

Westman B; Thörne A; Rooyackers O; Fredriksson K; Wernerman J; Hammarqvist F
Article: CLINICAL SCIENCE. 2009;117(9):313-319

Circulating and muscle glutathione turnover in human endotoxaemia.

Fläring UB; Hebert C; Wernerman J; Hammarqvist F; Rooyackers OE
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2009;53(6):717-723

Signs of critical illness polyneuropathy and myopathy can be seen early in the ICU course.

Ahlbeck K; Fredriksson K; Rooyackers O; Måbäck G; Remahl S; Ansved T; Eriksson L; Radell P
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2009;106(5):1479-1486

Systematic analysis of adaptations in aerobic capacity and submaximal energy metabolism provides a unique insight into determinants of human aerobic performance.

Vollaard NBJ; Constantin-Teodosiu D; Fredriksson K; Rooyackers O; Jansson E; Greenhaff PL; Timmons JA; Sundberg CJ
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2009;53(3):299-304

Muscle mitochondrial activity increases rapidly after an endotoxin challenge in human volunteers.

Fredriksson K; Fläring U; Guillet C; Wernerman J; Rooyackers O
Article: CLINICAL NUTRITION. 2008;27(6):816-821

The pattern of amino acid exchange across the brain is unaffected by intravenous glutamine supplementation in head trauma patients.

Berg A; Bellander BM; Wanecek M; Norberg A; Ungerstedt U; Rooyackers O; Wernerman J
Article: PLOS ONE. 2008;3(11):e3686

Dysregulation of mitochondrial dynamics and the muscle transcriptome in ICU patients suffering from sepsis induced multiple organ failure.

Fredriksson K; Tjäder I; Keller P; Petrovic N; Ahlman B; Schéele C; Wernerman J; Timmons JA; Rooyackers O
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2007;27(6):589-597

Enhanced in vivo protein synthesis in circulating immune cells of ICU patients.

Januszkiewicz A; Klaude M; Loré K; Andersson J; Ringdén O; Rooyackers O; Wernerman J
Article: CLINICAL SCIENCE. 2007;113(7):313-318

Knee replacement surgery as a human clinical model of the effects of ischaemia/reperfusion upon skeletal muscle.

Westman B; Weidenhielm L; Rooyackers O; Fredriksson K; Wernerman J; Hammarqvist F
Article: CRITICAL CARE MEDICINE. 2007;35(9 Suppl):S449-S453

Mitochondrial function in sepsis: respiratory versus leg muscle.

Fredriksson K; Rooyackers O
Article: CLINICAL SCIENCE. 2007;112(9):499-506

Proteasome proteolytic activity in skeletal muscle is increased in patients with sepsis.

Klaude M; Fredriksson K; Tjäder I; Hammarqvist F; Ahlman B; Rooyackers O; Wernerman J
Article: INTENSIVE CARE MEDICINE. 2007;33(4):660-666

Glutamine kinetics during intravenous glutamine supplementation in ICU patients on continuous renal replacement therapy.

Berg A; Norberg A; Martling C-R; Gamrin L; Rooyackers O; Wernerman J
Article: JOURNAL OF HEPATO-BILIARY-PANCREATIC SURGERY. 2007;14(2):183-188

Effect of extended cold ischemia time on glucose metabolism in liver grafts: experimental study in pigs.

Gillispie A; Rooyackers O; Wernerman J; Nowak G
Article: BMC GENOMICS. 2007;8:74

The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function.

Scheele C; Petrovic N; Faghihi MA; Lassmann T; Fredriksson K; Rooyackers O; Wahlestedt C; Good L; Timmons JA
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2006;101(6):1576-1580

Adipose tissue extracts plasma ammonia after sprint exercise in women and men.

Esbjörnsson M; Bülow J; Norman B; Simonsen L; Nowak J; Rooyackers O; Kaijser L; Jansson E
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2006;291(5):E1044-E1050

Derangements in mitochondrial metabolism in intercostal and leg muscle of critically ill patients with sepsis-induced multiple organ failure.

Fredriksson K; Hammarqvist F; Strigård K; Hultenby K; Ljungqvist O; Wernerman J; Rooyackers O
Article: INTENSIVE CARE MEDICINE. 2006;32(11):1741-1746

Intravenous glutamine supplementation to head trauma patients leaves cerebral glutamate concentration unaffected.

Berg A; Bellander BM; Wanecek M; Gamrin L; Elving A; Rooyackers O; Ungerstedt U; Wernerman J
Article: CLINICAL SCIENCE. 2006;110(1):93-99

Synthesis rates of total liver protein and albumin are both increased in patients with an acute inflammatory response.

Barle H; Hammarqvist F; Westman B; Klaude M; Rooyackers O; Garlick PJ; Wernerman J
Article: AMINO ACIDS. 2005;29(3):221-228

Elimination kinetics of L-alanyl-L-glutamine in ICU patients.

Berg A; Rooyackers O; Norberg A; Wernerman J
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2005;49(8):1101-1107

Effect of prolonged mechanical ventilation on diaphragm muscle mitochondria in piglets.

Fredriksson K; Radell P; Eriksson LI; Hultenby K; Rooyackers O
Article: INTENSIVE CARE MEDICINE. 2005;31(8):1072-1078

Temporal changes in whole-blood and plasma glutathione in ICU patients with multiple organ failure.

Fläring UB; Rooyackers OE; Hebert C; Bratel T; Hammarqvist F; Wernerman J
Article: CLINICAL SCIENCE. 2005;108(2):179-184

Determination of in vivo protein synthesis in human palatine tonsil.

Januszkiewicz A; Klaude M; Loré K; Andersson J; Ringdén O; Rooyackers O; Wernerman J
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2005;288(2):E360-E364

Amino acid metabolism in leg muscle after an endotoxin injection in healthy volunteers.

Vesali RF; Klaude M; Rooyackers O; Wernerman J
Article: CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE. 2005;8(1):77-82

Microdialysis to investigate tissue amino acid kinetics.

Rooyackers O
Article: CLINICAL SCIENCE. 2004;107(6):601-607

Impact of surgical trauma on human skeletal muscle protein synthesis.

Tjäder I; Essen P; Garlick PJ; McMnurlan MA; Rooyackers O; Wernerman J
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2004;89(11):5382-5386

Intensive insulin treatment in critically ill trauma patients normalizes glucose by reducing endogenous glucose production.

Thorell A; Rooyackers O; Myrenfors P; Soop M; Nygren J; Ljungqvist OH
Article: CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE. 2004;7(5):515-521

Microdialysis methods for measuring human metabolism.

Rooyackers O; Thorell A; Nygren J; Ljungqvist O
Article: CLINICAL NUTRITION. 2004;23(4):743-752

Insulin stimulated glucose disposal in peripheral tissues studied with microdialysis and stable isotope tracers.

Rooyackers O; Myrenfors P; Nygren J; Thorell A; Ljungqvist O
Article: METABOLISM-CLINICAL AND EXPERIMENTAL. 2004;53(8):1076-1080

Contractile protein breakdown in human leg skeletal muscle as estimated by [2H3]-3-methylhistidine: a new method.

Vesali RF; Klaude M; Thunblad L; Rooyackers OE; Wernerman J
Article: INTENSIVE CARE MEDICINE. 2004;30(2):266-275

Effects on skeletal muscle of intravenous glutamine supplementation to ICU patients.

Tjäder I; Rooyackers O; Forsberg A-M; Vesali RF; Garlick PJ; Wernerman J
Article: INTENSIVE CARE MEDICINE. 2003;29(12):2193-2198

Temporal changes in muscle glutathione in ICU patients.

Fläring UB; Rooyackers OE; Wernerman J; Hammarqvist F
Article: PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 2003;446(2):261-269

Reduced oxidative power but unchanged antioxidative capacity in skeletal muscle from aged humans.

Tonkonogi M; Fernström M; Walsh B; Ji LL; Rooyackers O; Hammarqvist F; Wernerman J; Sahlin K
Article: CLINICAL SCIENCE. 2003;104(3):275-282

Glutamine attenuates post-traumatic glutathione depletion in human muscle.

Fläring UB; Rooyackers OE; Wernerman J; Hammarqvist F
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2003;88(1):285-291

Effects of the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes.

Andrews RC; Rooyackers O; Walker BR
Article: CLINICAL NUTRITION. 2002;21(6):505-514

Longitudinal pattern of glutamine/glutamate balance across the leg in long-stay intensive care unit patients.

Vesali RF; Klaude M; Rooyackers OE; TJäder I; Barle H; Wernerman J
Article: JOURNAL OF INHERITED METABOLIC DISEASE. 2002;25(7):577-584

Glutathione synthetase deficiency: is gamma-glutamylcysteine accumulation a way to cope with oxidative stress in cells with insufficient levels of glutathione?

Ristoff E; Hebert C; Njålsson R; Norgren S; Rooyackers O; Larsson A
Article: DIABETES. 2002;51(7):2074-2081

Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes.

Musi N; Hirshman MF; Nygren J; Svanfeldt M; Bavenholm P; Rooyackers O; Zhou G; Williamson JM; Ljunqvist O; Efendic S; Moller DE; Thorell A; Goodyear LJ
Article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2000;82(5-6):493-498

Different effects of corticosteroid-induced muscle wasting compared with undernutrition on rat diaphragm energy metabolism.

Koerts-de Lang E; Schols AM; Rooyackers OE; Gayan-Ramirez G; Decramer M; Wouters EF
Article: JOURNAL OF PHYSIOLOGY-LONDON. 2000;525 Pt 1(Pt 1):271-281

Effect of oral glucose on leucine turnover in human subjects at rest and during exercise at two levels of dietary protein.

Bowtell JL; Leese GP; Smith K; Watt PW; Nevill A; Rooyackers O; Wagenmakers AJ; Rennie MJ
Article: JOURNAL OF APPLIED PHYSIOLOGY. 1998;85(5):1744-1752

Modulation of whole body protein metabolism, during and after exercise, by variation of dietary protein.

Bowtell JL; Leese GP; Smith K; Watt PW; Nevill A; Rooyackers O; Wagenmakers AJ; Rennie MJ
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1997;273(4):e790-e800

Effects of aging on in vivo synthesis of skeletal muscle myosin heavy-chain and sarcoplasmic protein in humans.

Balagopal P; Rooyackers OE; Adey DB; Ades PA; Nair KS
Article: CLINICAL SCIENCE. 1997;92(2):189-195

Contraction failure of skeletal muscle of rats recovering from critical illness.

Rooyackers OE; Hesselink MK; Wagenmakers AJ
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1996;93(26):15364-15369

Effect of age on in vivo rates of mitochondrial protein synthesis in human skeletal muscle.

Rooyackers OE; Adey DB; Ades PA; Nair KS
Article: CLINICAL SCIENCE. 1996;91(4):475-481

Mitochondrial protein content and in vivo synthesis rates in skeletal muscle from critically ill rats.

Rooyackers OE; Kersten AH; Wagenmakers AJ
Article: METABOLISM-CLINICAL AND EXPERIMENTAL. 1996;45(10):1279-1283

Tracer kinetics are of limited value to measure in vivo protein synthesis and degradation rates in muscle of anesthesized rats.

Rooyackers OE; Wagenmakers AJ
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 1996;1315(1):55-60

Derangement in aerobic and anaerobic energy metabolism in skeletal muscle of critically ill and recovering rats.

Rooyackers OE; Gijsen AP; Saris WH; Soeters PB; Wagenmakers AJ
Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 1995;25(8):548-552

Prolonged activation of the branched-chain alpha-keto acid dehydrogenase complex in muscle of zymosan treated rats.

Rooyackers OE; Senden JM; Soeters PB; Saris WH; Wagenmakers AJ
Article: CLINICAL NUTRITION. 1995;14(2):105-115

Effect of an enterally administered glutamine-rich protein on the catabolic response to a zymosan challenge in rats.

Rooyackers OE; Soeters PB; Saris WH; Wagenmakers AJ
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Letter: NATURE. 2023;621(7977):E7-E26

A second update on mapping the human genetic architecture of COVID-19.

COVID-19 Host Genetics Initiative
Review: CRITICAL CARE. 2023;27(1):258

How to avoid harm with feeding critically ill patients: a synthesis of viewpoints of a basic scientist, dietitian and intensivist.

Reintam Blaser A; Rooyackers O; Bear DE
Editorial comment: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2022;206(6):660-661

Anabolic Resistance: An Uncomfortable Truth for Clinical Trials in Preventing Intensive Care-acquired Weakness and Physical Functional Impairment.

Puthucheary Z; Rooyackers O
Editorial comment: NATURE. 2022;608(7921):E1-E10

A first update on mapping the human genetic architecture of COVID-19.

COVID-19 Host Genetics Initiative
Review: CURRENT OPINION IN CRITICAL CARE. 2022;28(4):367-373

Protein metabolism in critical illness.

Chapple L-AS; van Gassel RJJ; Rooyackers O
Editorial comment: NATURE IMMUNOLOGY. 2022;23(6):861-864

Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19.

Hultström M; Frithiof R; Grip J; Lindelöf L; Rooijackers O; Pigazzini S; Niemi M; Cordioli M; Nkambule L; Maricic T; Ekdahl KN; Nilsson B; Lipcsey M; Zeberg H; Eriksson O
Review: CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE. 2022;25(2):88-92

HMB and leucine supplementation during critical illness and recovery.

Bear DE; Rooyackers O
Review: CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE. 2021;24(1):71-78

Protein absorption and kinetics in critical illness.

Liebau F; Deane AM; Rooyackers O
Review: CRITICAL CARE. 2020;24(1):224

Gastrointestinal dysfunction in the critically ill: a systematic scoping review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intensive Care Medicine.

Reintam Blaser A; Preiser J-C; Fruhwald S; Wilmer A; Wernerman J; Benstoem C; Casaer MP; Starkopf J; van Zanten A; Rooyackers O; Jakob SM; Loudet CI; Bear DE; Elke G; Kott M; Lautenschläger I; Schäper J; Gunst J; Stoppe C; Nobile L; Fuhrmann V; Berger MM; Oudemans-van Straaten HM; Arabi YM; Deane AM; Working Group on Gastrointestinal Function within
Review: CRITICAL CARE. 2019;23(1):318

Metabolic support in the critically ill: a consensus of 19.

Wernerman J; Christopher KB; Annane D; Casaer MP; Coopersmith CM; Deane AM; De Waele E; Elke G; Ichai C; Karvellas CJ; McClave SA; Oudemans-van Straaten HM; Rooyackers O; Stapleton RD; Takala J; van Zanten ARH; Wischmeyer PE; Preiser J-C; Vincent J-L
Letter: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2019;317(3):E433-E434

The intrinsically labeled protein approach is the preferred method to quantify the release of dietary protein-derived amino acids into the circulation.

Trommelen J; Holwerda AM; Nyakayiru J; Gorissen SHM; Rooyackers O; Burd NA; Boirie Y; van Loon LJC
Review: CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE. 2019;22(2):146-151

Can exercise and nutrition stimulate muscle protein gain in the ICU patient?

Sundström-Rehal M; Tardif N; Rooyackers O
Corrigendum: CLINICAL NUTRITION. 2018;37(3):1091

Corrigendum to 'The effect of perioperative glucose control on postoperative insulin resistance' [Clin Nutr 31 (5) (2012) 676-681].

Blixt C; Ahlstedt C; Ljungqvist O; Isaksson B; Kalman S; Rooyackers O
Review: CURRENT OPINION IN CRITICAL CARE. 2017;23(4):264-268

Muscle metabolism.

Tardif N; Grip J; Rooyackers O
Editorial comment: CRITICAL CARE. 2017;21(1):106

High protein intake without concerns?

Rooyackers O; Sundström Rehal M; Liebau F; Norberg Å; Wernerman J
Review: CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE. 2017;20(3):181-185

Omics and cachexia.

Twelkmeyer B; Tardif N; Rooyackers O
Published conference paper: JOURNAL OF PARENTERAL AND ENTERAL NUTRITION. 2017;41(2):208-216

Proceedings of the 2016 Clinical Nutrition Week Research Workshop-The Optimal Dose of Protein Provided to Critically Ill Patients.

Heyland DK; Rooyakers O; Mourtzakis M; Stapleton RD
Review: SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. 2016;54:92-103

Omics/systems biology and cancer cachexia.

Gallagher IJ; Jacobi C; Tardif N; Rooyackers O; Fearon K
Editorial comment: CLINICAL NUTRITION. 2016;35(3):543-544

Who is blind(ed) for what??

Wernerman J; Rooyackers O
Corrigendum: CRITICAL CARE. 2016;20(1):104

Erratum to: 'Measuring energy expenditure in the intensive care unit: a comparison of indirect calorimetry by E-sCOVX and Quark RMR with Deltatrac II in mechanically ventilated critically ill patients'.

Sundström Rehal M; Fiskaare E; Tjäder I; Norberg Å; Rooyackers O; Wernerman J
Review: CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE. 2016;19(2):120-124

Does feeding induce maximal stimulation of protein balance?

Liebau F; Norberg Å; Rooyackers O
Editorial comment: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2015;59(6):683-684

Metabolic control, does it matter?

Nygren J; Rooyackers O
Review: APPLIED PHYSIOLOGY NUTRITION AND METABOLISM. 2015;40(1):1-9

Optimizing the measurement of mitochondrial protein synthesis in human skeletal muscle.

Burd NA; Tardif N; Rooyackers O; van Loon LJC
Letter: PEDIATRIC CRITICAL CARE MEDICINE. 2014;15(8):793-794

The authors reply.

Vanhorebeek I; Gielen M; Wouters PJ; Mesotten D; Wernerman J; Rooyackers O; Van den Berghe G
Review: CRITICAL CARE. 2014;18(3):226

Continuous glucose control in the ICU: report of a 2013 round table meeting.

Wernerman J; Desaive T; Finfer S; Foubert L; Furnary A; Holzinger U; Hovorka R; Joseph J; Kosiborod M; Krinsley J; Mesotten D; Nasraway S; Rooyackers O; Schultz MJ; Van Herpe T; Vigersky RA; Preiser J-C
Editorial comment: CRITICAL CARE. 2014;18(3):144

Imaging opens possibilities both to target and to evaluate nutrition in critical illness.

Rooyackers O; Wernerman J
Editorial comment: CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE. 2014;17(1):59-60

Amino acids and proteins important for all; from stem cells, to the critically ill patient and even general bone health.

Rooyackers O; Brosnan JT
Published conference paper: CLINICAL NUTRITION. 2013;32(1):118-121

Indirect calorimetry in mechanically ventilated patients. A systematic comparison of three instruments.

Sundström M; Tjäder I; Rooyackers O; Wernerman J
Editorial comment: CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE. 2013;16(1):56

Amino acids: the most versatile nutrients.

Brosnan JT; Rooyackers O
Editorial comment: CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE. 2012;15(1):47-48

The importance of amino acids as independent metabolites, signalling molecules and as building blocks for protein.

Brosnan J; Rooyackers O
Review: BRITISH JOURNAL OF SURGERY. 2007;94(11):1342-1350

Randomized clinical trial of the effect of preoperative oral carbohydrate treatment on postoperative whole-body protein and glucose kinetics.

Svanfeldt M; Thorell A; Hausel J; Soop M; Rooyackers O; Nygren J; Ljungqvist O
Other: CLINICAL NUTRITION. 2003;22(4):423

Report from the third meeting on tracer network for metabolic research.

Rooyackers O; Darmaun D; Walrand S; Boirie Y; Bülow J; Ljungqvist O; Wernerman J
Other: CLINICAL NUTRITION. 2002;21(3):265-266

Report from the 2nd meeting on tracer Network for Metabolic Research.

Rooyackers O; Biolo G; Ljungqvist O; Wernerman J
Other: CLINICAL NUTRITION. 2001;20(1):93

Report from founding meeting on Tracer Network for Metabolic Research.

Rooyackers O; Ljungqvist O; Wernerman J
Editorial comment: CLINICAL NUTRITION. 2000;19(3):145-146

Methods, who cares?

Wernerman J; Rooyackers O
Review: ANNUAL REVIEW OF NUTRITION. 1997;17:457-485

Hormonal regulation of human muscle protein metabolism.

Rooyackers OE; Nair KS
Published conference paper: MUSCLE & NERVE. 1997;5:S93-S96

Measurement of synthesis rates of specific muscle proteins using needle biopsy samples.

Rooyackers OE; Balagopal P; Nair KS
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Forskningsbidrag

The role of mitochondria in organ failure with sepsis

Swedish Research Council

1 January 2010 - 31 December 2012

Anställningar

Professor, Klinisk vetenskap, intervention och teknik, Karolinska Institutet, 2012-

Examina och utbildning

Docent, Metabolismforskning, Karolinska Institutet, 2002

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