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Mats Lekander


Postadress : Institutionen för klinisk neurovetenskap (CNS), K8, Psykologi Lekander, Nobels Väg 9 171 77 Stockholm
Leveransadress : Nobels Väg 9 171 77 Stockholm


A global measure of sickness behaviour: Development of the Sickness Questionnaire
Andreasson A, Wicksell Rk, Lodin K, Karshikoff B, Axelsson J, Lekander M
Journal of health psychology 2018;23(11):1452-1463

A randomized controlled intervention of workplace-based group cognitive behavioral therapy for insomnia
Schiller H, Söderström M, Lekander M, Rajaleid K, Kecklund G
International archives of occupational and environmental health 2018;91(4):413-424

Communication of health in experimentally sick men and women: A pilot study
Lasselin J, Lekander M, Paues-göranson S, Olsson Mj, Axelsson J
Psychoneuroendocrinology 2018;87():188-195

Effects of late-night short-sleep on in-home polysomnography: relation to adult age and sex
Åkerstedt T, Lekander M, Nilsonne G, Tamm S, D'onofrio P, Kecklund G, et al
Journal of sleep research 2018;27(4):e12626-

Effects of psychological interventions on systemic levels of inflammatory biomarkers in humans: A systematic review and meta-analysis
O'toole Ms, Bovbjerg Dh, Renna Me, Lekander M, Mennin Ds, Zachariae R
Brain, behavior, and immunity 2018;74():68-78

Evidence of fatigue, disordered sleep and peripheral inflammation, but not increased brain TSPO expression, in seasonal allergy: A [11C]PBR28 PET study
Tamm S, Cervenka S, Forsberg A, Estelius J, Grunewald J, Gyllfors P, et al
Brain, behavior, and immunity 2018;68():146-157

Identification of acutely sick people and facial cues of sickness
Axelsson J, Sundelin T, Olsson Mj, Sorjonen K, Axelsson C, Lasselin J, et al
Proceedings. Biological sciences 2018;285(1870):-

Man flu is related to health communication rather than symptoms and suffering
Axelsson J, Lasselin J, Lekander M
BMJ (Clinical research ed.) 2018;360():k450-

Stepped care in primary care - guided self-help and face-to-face cognitive behavioural therapy for common mental disorders: a randomized controlled trial
Salomonsson S, Santoft F, Lindsäter E, Ejeby K, Ljótsson B, Öst Lg, et al
Psychological medicine 2018;48(10):1644-1654

Total workload and recovery in relation to worktime reduction: a randomised controlled intervention study with time-use data
Schiller H, Lekander M, Rajaleid K, Hellgren C, Åkerstedt T, Barck-holst P, et al
Occupational and environmental medicine 2018;75(3):218-226

Associations between self-rated health, sickness behaviour and inflammatory markers in primary care patients with allergic asthma: a longitudinal study
Lodin K, Lekander M, Syk J, Alving K, Andreasson A
NPJ primary care respiratory medicine 2017;27(1):67-

Behavioral and neural correlates to multisensory detection of sick humans
Regenbogen C, Axelsson J, Lasselin J, Porada Dk, Sundelin T, Peter Mg, et al
Proceedings of the National Academy of Sciences of the United States of America 2017;114(24):6400-6405

Brief report: Contemplate your symptoms and re-evaluate your health. A study on working adults
Andreasson A, Schiller H, Åkerstedt T, Berntson E, Kecklund G, Lekander M
Journal of health psychology 2017;():1359105317715090-

Circulating Interleukin 6 in Parkinson Disease
Nilsonne G, Lekander M
JAMA neurology 2017;74(5):607-608

Cognitive-behavioural therapy and return-to-work intervention for patients on sick leave due to common mental disorders: a randomised controlled trial
Salomonsson S, Santoft F, Lindsäter E, Ejeby K, Ljótsson B, Öst Lg, et al
Occupational and environmental medicine 2017;74(12):905-912

Intrinsic brain connectivity after partial sleep deprivation in young and older adults: results from the Stockholm Sleepy Brain study
Nilsonne G, Tamm S, Schwarz J, Almeida R, Fischer H, Kecklund G, et al
Scientific reports 2017;7(1):9422-

Lipopolysaccharide Alters Motivated Behavior in a Monetary Reward Task: a Randomized Trial
Lasselin J, Treadway Mt, Lacourt Te, Soop A, Olsson Mj, Karshikoff B, et al
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2017;42(4):801-810

Longitudinal co-variations between inflammatory cytokines, lung function and patient reported outcomes in patients with asthma
Lodin K, Lekander M, Syk J, Alving K, Petrovic P, Andreasson A
PloS one 2017;12(9):e0185019-

Negative effects of restricted sleep on facial appearance and social appeal
Sundelin T, Lekander M, Sorjonen K, Axelsson J
Royal Society open science 2017;4(5):160918-

Skin colour changes during experimentally-induced sickness
Henderson Aj, Lasselin J, Lekander M, Olsson Mj, Powis Sj, Axelsson J, et al
Brain, behavior, and immunity 2017;60():312-318

The effect of sleep restriction on empathy for pain: An fMRI study in younger and older adults
Tamm S, Nilsonne G, Schwarz J, Lamm C, Kecklund G, Petrovic P, et al
Scientific reports 2017;7(1):12236-

The impact of exposure-based cognitive behavior therapy for severe health anxiety on self-rated health: Results from a randomized trial
Hedman-lagerlöf E, Axelsson E, Andersson E, Ljótsson B, Andreasson A, Lekander M
Journal of psychosomatic research 2017;103():9-14

The impact of reduced worktime on sleep and perceived stress - a group randomized intervention study using diary data
Schiller H, Lekander M, Rajaleid K, Hellgren C, Åkerstedt T, Barck-holst P, et al
Scandinavian journal of work, environment & health 2017;43(2):109-116

Yawning, a thermoregulatory mechanism during fever? A study of yawning frequency and its predictors during experimentally induced sickness
Marraffa A, Lekander M, Solsjö P, Olsson Mj, Lasselin J, Axelsson J
Physiology & behavior 2017;182():27-33

A Clinical Pilot Study of Individual and Group Treatment for Adolescents with Chronic Pain and Their Parents: Effects of Acceptance and Commitment Therapy on Functioning
Kanstrup M, Wicksell Rk, Kemani M, Wiwe Lipsker C, Lekander M, Holmström L
Children (Basel, Switzerland) 2016;3(4):-

Cost effectiveness of internet-based cognitive behaviour therapy and behavioural stress management for severe health anxiety
Hedman E, Andersson E, Ljótsson B, Axelsson E, Lekander M
BMJ open 2016;6(4):e009327-

Diurnal Variation of Circulating Interleukin-6 in Humans: A Meta-Analysis
Nilsonne G, Lekander M, Åkerstedt T, Axelsson J, Ingre M
PloS one 2016;11(11):e0165799-

Exposure-based cognitive-behavioural therapy via the Internet and as bibliotherapy for somatic symptom disorder and illness anxiety disorder: randomised controlled trial
Hedman E, Axelsson E, Andersson E, Lekander M, Ljotsson B

Health anxiety in a disease-avoidance framework: Investigation of anxiety, disgust and disease perception in response to sickness cues
Hedman E, Lekander M, Karshikoff B, Ljótsson B, Axelsson E, Axelsson J
Journal of abnormal psychology 2016;125(7):868-878

Health at the ballot box: disease threat does not predict attractiveness preference in British politicians
Nilsonne G, Renberg A, Tamm S, Lekander M
Royal Society open science 2016;3(3):160049-

Intrinsic functional connectivity of insular cortex and symptoms of sickness during acute experimental inflammation
Lekander M, Karshikoff B, Johansson E, Soop A, Fransson P, Lundström Jn, et al
Brain, behavior, and immunity 2016;56():34-41

In vivo evidence of a functional association between immune cells in blood and brain in healthy human subjects
Kanegawa N, Collste K, Forsberg A, Schain M, Arakawa R, Jucaite A, et al
Brain, behavior, and immunity 2016;54():149-157

Is poor self-rated health associated with low-grade inflammation in 43,110 late adolescent men of the general population? A cross-sectional study
Warnoff C, Lekander M, Hemmingsson T, Sorjonen K, Melin B, Andreasson A
BMJ open 2016;6(4):e009440-

Low-grade inflammation may moderate the effect of behavioral treatment for chronic pain in adults
Lasselin J, Kemani Mk, Kanstrup M, Olsson Gl, Axelsson J, Andreasson A, et al
Journal of behavioral medicine 2016;39(5):916-24

Mood disturbance during experimental endotoxemia: Predictors of state anxiety as a psychological component of sickness behavior
Lasselin J, Elsenbruch S, Lekander M, Axelsson J, Karshikoff B, Grigoleit Js, et al
Brain, behavior, and immunity 2016;57():30-37

Parallel reductions of IgE and exhaled nitric oxide after optimized anti-inflammatory asthma treatment
Syk J, Malinovschi A, Borres Mp, Undén Al, Andreasson A, Lekander M, et al
Immunity, inflammation and disease 2016;4(2):182-190

Post-traumatic stress disorder and interleukin 6
Nilsonne G, Hilgard J, Lekander M, Arnberg Fk
The lancet. Psychiatry 2016;3(3):200-1

Processes of change in Acceptance and Commitment Therapy and Applied Relaxation for long-standing pain
Kemani Mk, Hesser H, Olsson Gl, Lekander M, Wicksell Rk
European journal of pain (London, England) 2016;20(4):521-31

Self-rated health and interleukin-6: Longitudinal relationships in older adults
Arnberg Fk, Lekander M, Morey Jn, Segerstrom Sc
Brain, behavior, and immunity 2016;54():226-232

Why sickness hurts: A central mechanism for pain induced by peripheral inflammation
Karshikoff B, Jensen Kb, Kosek E, Kalpouzos G, Soop A, Ingvar M, et al
Brain, behavior, and immunity 2016;57():38-46

Effect of long-term sleep restriction and subsequent recovery sleep on the diurnal rhythms of white blood cell subpopulations
Lasselin J, Rehman Ju, Åkerstedt T, Lekander M, Axelsson J
Brain, behavior, and immunity 2015;47():93-9

Efficacy and Cost-effectiveness of Acceptance and Commitment Therapy and Applied Relaxation for Longstanding Pain: A Randomized Controlled Trial
Kemani Mk, Olsson Gl, Lekander M, Hesser H, Andersson E, Wicksell Rk
The Clinical journal of pain 2015;31(11):1004-16

Leukocyte telomere length and hippocampus volume: a meta-analysis
Nilsonne G, Tamm S, Månsson Kn, Åkerstedt T, Lekander M
F1000Research 2015;4():1073-

Modality and sex differences in pain sensitivity during human endotoxemia
Karshikoff B, Lekander M, Soop A, Lindstedt F, Ingvar M, Kosek E, et al
Brain, behavior, and immunity 2015;46():35-43

Optimal cut-off points on the health anxiety inventory, illness attitude scales and whiteley index to identify severe health anxiety
Hedman E, Lekander M, Ljótsson B, Lindefors N, Rück C, Andersson G, et al
PloS one 2015;10(4):e0123412-

Predictors in Internet-delivered cognitive behavior therapy and behavioral stress management for severe health anxiety
Hedman E, Andersson E, Lekander M, Ljótsson B
Behaviour research and therapy 2015;64():49-55

Psychometric properties of Internet-administered measures of health anxiety: an investigation of the Health Anxiety Inventory, the Illness Attitude Scales, and the Whiteley Index
Hedman E, Ljótsson B, Andersson E, Andersson G, Lindefors N, Rück C, et al
Journal of anxiety disorders 2015;31():32-7

Sick man walking: Perception of health status from body motion
Sundelin T, Karshikoff B, Axelsson E, Höglund Co, Lekander M, Axelsson J
Brain, behavior, and immunity 2015;48():53-6

Clinical effectiveness and cost-effectiveness of Internet- vs. group-based cognitive behavior therapy for social anxiety disorder: 4-year follow-up of a randomized trial
Hedman E, El Alaoui S, Lindefors N, Andersson E, Rück C, Ghaderi A, et al
Behaviour research and therapy 2014;59():20-9

Do sleep, stress, and illness explain daily variations in fatigue? A prospective study
Akerstedt T, Axelsson J, Lekander M, Orsini N, Kecklund G
Journal of psychosomatic research 2014;76(4):280-5

Internet-delivered exposure-based cognitive-behavioural therapy and behavioural stress management for severe health anxiety: randomised controlled trial
Hedman E, Axelsson E, Görling A, Ritzman C, Ronnheden M, El Alaoui S, et al
The British journal of psychiatry : the journal of mental science 2014;205(4):307-14

Personality change following internet-based cognitive behavior therapy for severe health anxiety
Hedman E, Andersson G, Lindefors N, Gustavsson P, Lekander M, Rück C, et al
PloS one 2014;9(12):e113871-

Sleep polysomnography and reported stress across 6 weeks
Åkerstedt T, Lekander M, Petersén H, Kecklund G, Axelsson J
Industrial health 2014;52(1):36-42

Sudden gains in internet-based cognitive behaviour therapy for severe health anxiety
Hedman E, Lekander M, Ljótsson B, Lindefors N, Rück C, Hofmann Sg, et al
Behaviour research and therapy 2014;54():22-9

The scent of disease: human body odor contains an early chemosensory cue of sickness
Olsson Mj, Lundström Jn, Kimball Ba, Gordon Ar, Karshikoff B, Hosseini N, et al
Psychological science 2014;25(3):817-23

Anti-inflammatory treatment of atopic asthma guided by exhaled nitric oxide: a randomized, controlled trial
Syk J, Malinovschi A, Johansson G, Undén Al, Andreasson A, Lekander M, et al
The journal of allergy and clinical immunology. In practice 2013;1(6):639-48.e1

Cues of fatigue: effects of sleep deprivation on facial appearance
Sundelin T, Lekander M, Kecklund G, Van Someren Ej, Olsson A, Axelsson J
Sleep 2013;36(9):1355-60

Development of atopic disease and disturbed sleep in childhood and adolescence--a longitudinal population-based study
Jernelöv S, Lekander M, Almqvist C, Axelsson J, Larsson H
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2013;43(5):552-9

Effects of sustained sleep restriction on mitogen-stimulated cytokines, chemokines and T helper 1/ T helper 2 balance in humans
Axelsson J, Rehman Ju, Akerstedt T, Ekman R, Miller Ge, Höglund Co, et al
PloS one 2013;8(12):e82291-

Inflammation and positive affect are associated with subjective health in women of the general population
Andreasson An, Szulkin R, Undén Al, Von Essen J, Nilsson Lg, Lekander M
Journal of health psychology 2013;18(3):311-20

Mediators in internet-based cognitive behavior therapy for severe health anxiety
Hedman E, Andersson E, Andersson G, Lindefors N, Lekander M, Rück C, et al
PloS one 2013;8(10):e77752-

Mediators in psychological treatment of social anxiety disorder: individual cognitive therapy compared to cognitive behavioral group therapy
Hedman E, Mörtberg E, Hesser H, Clark Dm, Lekander M, Andersson E, et al
Behaviour research and therapy 2013;51(10):696-705

Predictors of outcome in Internet-based cognitive behavior therapy for severe health anxiety
Hedman E, Lindefors N, Andersson G, Andersson E, Lekander M, Rück C, et al
Behaviour research and therapy 2013;51(10):711-7

Subjective health perception in healthy young men changes in response to experimentally restricted sleep and subsequent recovery sleep
Lekander M, Andreasson An, Kecklund G, Ekman R, Ingre M, Akerstedt T, et al
Brain, behavior, and immunity 2013;34():43-6

The daily variation in sleepiness and its relation to the preceding sleep episode--a prospective study across 42 days of normal living
Akerstedt T, Axelsson J, Lekander M, Orsini N, Kecklund G
Journal of sleep research 2013;22(3):258-65

Allergy influences the inflammatory status of the brain and enhances tau-phosphorylation
Sarlus H, Höglund Co, Karshikoff B, Wang X, Lekander M, Schultzberg M, et al
Journal of cellular and molecular medicine 2012;16(10):2401-12

Efficacy of a behavioral self-help treatment with or without therapist guidance for co-morbid and primary insomnia -a randomized controlled trial
Jernelov S, Lekander M, Blom K, Rydh S, Ljotsson B, Axelsson J, et al

Negative emotions and cytokines in maternal and cord serum at preterm birth
Fransson E, Dubicke A, Byström B, Ekman-ordeberg G, Hjelmstedt A, Lekander M
American journal of reproductive immunology (New York, N.Y. : 1989) 2012;67(6):506-14

Predicting sleep quality from stress and prior sleep--a study of day-to-day covariation across six weeks
Åkerstedt T, Orsini N, Petersen H, Axelsson J, Lekander M, Kecklund G
Sleep medicine 2012;13(6):674-9

Pro-inflammatory cytokines are elevated in adolescent females with emotional disorders not treated with SSRIs
Blom Eh, Lekander M, Ingvar M, Asberg M, Mobarrez F, Serlachius E

Serotonin-1A receptor polymorphism (rs6295) associated with thermal pain perception
Lindstedt F, Karshikoff B, Schalling M, Olgart Höglund C, Ingvar M, Lekander M, et al
PloS one 2012;7(8):e43221-

Cytokines and memory across the mature life span of women
Lekander M, Von Essen J, Schultzberg M, Andreasson An, Garlind A, Hansson Lo, et al

Getting the Grip on Nonspecific Treatment Effects: Emesis in Patients Randomized to Acupuncture or Sham Compared to Patients Receiving Standard Care
Enblom A, Lekander M, Hammar M, Johnsson A, Onelov E, Ingvar M, et al
PLOS ONE 2011;6(3):e14766-

Learning in a simple biological system: a pilot study of classical conditioning of human macrophages in vitro
Nilsonne G, Appelgren A, Axelsson J, Fredrikson M, Lekander M

Levels of Tumour Necrosis Factor-Alpha and Interleukin-6 in Severely Ill Patients with Eating Disorders
Ahren-moonga J, Lekander M, Von Blixen N, Ronnelid J, Holmgren S, Af Klinteberg B

Maternal Bereavement and Childhood Asthma-Analyses in Two Large Samples of Swedish Children
Fang F, Hoglund Co, Arck P, Lundholm C, Langstrom N, Lichtenstein P, et al
PLOS ONE 2011;6(11):e27202-

Physical Activity, Stress, and Self-Reported Upper Respiratory Tract Infection
Fondell E, Lagerros Yt, Sundberg Cj, Lekander M, Balter O, Rothman Kj, et al

Short natural sleep is associated with higher T cell and lower NK cell activities
Fondell E, Axelsson J, Franck K, Ploner A, Lekander M, Balter K, et al

Acupressure to reduce labor pain: a randomized controlled trial
Hjelmstedt A, Shenoy St, Stener-victorin E, Lekander M, Bhat M, Balakumaran L, et al

Associations Between Leptin and Self-Rated Health in Men and Women
Andreasson An, Jernelov S, Szulkin R, Unden Al, Brismar K, Lekander M
GENDER MEDICINE 2010;7(3):261-9

Social problem solving, autobiographical memory, trauma, and depression in women with borderline personality disorder and a history of suicide attempts
Maurex L, Lekander M, Nilsonne A, Andersson Ee, Asberg M, Ohman A

The Psychological Inflexibility in Pain Scale (PIPS) - Statistical properties and model fit of an instrument to assess change processes in pain related disability
Wicksell Rk, Lekander M, Sorjonen K, Olsson Gl
EUROPEAN JOURNAL OF PAIN 2010;14(7):771.e1-14

Cytokine Inhibition after Glucocorticoid Exposure in Healthy Men with Low versus High Basal Cortisol Levels
Lekander M, Axen J, Knutsson U, Hoglund Co, Werner S, Wikstrom Ac, et al

Effects of Examination Stress on Psychological Responses, Sleep and Allergic Symptoms in Atopic and Non-Atopic Students
Jernelov S, Hoglund Co, Axelsson J, Axen J, Gronneberg R, Grunewald J, et al

Evaluating the effectiveness of exposure and acceptance strategies to improve functioning and quality of life in longstanding pediatric pain - A randomized controlled trial
Wicksell Rk, Melin L, Lekander M, Olsson Gl
PAIN 2009;141(3):248-57

Novel Biochemical Markers of Psychosocial Stress in Women
Asberg M, Nygren A, Leopardi R, Rylander G, Peterson U, Wilczek L, et al
PLOS ONE 2009;4(1):e3590-

Sleep Homeostasis During Repeated Sleep Restriction and Recovery: Support from EEG Dynamics
Akerstedt T, Kecklund G, Ingre M, Lekander M, Axelsson J
SLEEP 2009;32(2):217-22

Systemic immune effects of adjuvant chemotherapy with 5-fluorouracil, epirubicin and cyclophosphamide and/or radiotherapy in breast cancer: a longitudinal study
Mozaffari F, Lindemalm C, Choudhury A, Granstam-bjorneklett H, Lekander M, Nilsson B, et al

Immune response, depression and fatigue in relation to support intervention in mammary cancer patients
Lindemalm C, Mozaffari F, Choudhury A, Granstam-bjorneklett H, Lekander M, Nilsson B, et al

Loss of a child and the risk of amyotrophic lateral sclerosis
Fang F, Ye W, Fall K, Lekander M, Wigzell H, Sparen P, et al

Sleepiness and performance in response to repeated sleep restriction and subsequent recovery during semi-laboratory conditions
Axelsson J, Kecklund G, Akerstedt T, Donofrio P, Lekander M, Ingre M

A putative role for cytokines in the impaired appetite in depression
Andreasson A, Arborelius L, Erlanson-albertsson C, Lekander M

Inflammatory cytokines, behaviour and age as determinants of self-rated health in women
Unden Al, Andreasson A, Elofsson S, Brismar K, Mathsson L, Ronnelid J, et al
CLINICAL SCIENCE 2007;112(5-6):363-73

NK-cell and T-cell functions in patients with breast cancer: effects of surgery and adjuvant chemo- and radiotherapy
Mozaffari F, Lindemalm C, Choudhury A, Granstam-bjorneklett H, Helander I, Lekander M, et al

Changes in immune regulation in response to examination stress in atopic and healthy individuals
Hoglund Co, Axen J, Kemi C, Jernelov S, Grunewald J, Muller-suur C, et al

Less effective executive functioning after one night's sleep deprivation
Nilsson Jp, Soderstrom M, Karlsson Au, Lekander M, Akerstedt T, Lindroth Ne, et al

Self-rated health and vital exhaustion, but not depression, is related to inflammation in women with coronary heart disease
Janszky I, Lekander M, Blom M, Georgiades A, Ahnve S

Support group for cancer patients. Does it improve their physical and psychological wellbeing? A pilot study
Lindemalm C, Strang P, Lekander M

Inflammatory markers and heart rate variability in women with coronary heart disease
Janszky I, Ericson M, Lekander M, Blom M, Buhlin K, Georgiades A, et al

Self-rated health is related to levels of circulating cytokines
Lekander M, Elofsson S, Neve Im, Hansson Lo, Unden Al

Ecological immunology - The role of the immune system in psychology and neuroscience
Lekander M

Neuroimmune relations in patients with fibromyalgia: a positron emission tomography study
Lekander M, Fredrikson M, Wik G
NEUROSCIENCE LETTERS 2000;282(3):193-6

[The immune system is affected by psychological factors. High stress levels can change susceptibility to infection and allergy]
Lekander M
Lakartidningen 1999;96(44):4807-11

Human brain-immune relationships: A PET study
Wik G, Lekander M, Fredrikson M

Immune effects of relaxation during chemotherapy for ovarian cancer
Lekander M, Furst Cj, Rotstein S, Hursti Tj, Fredrikson M

Social support and immune status during and after chemotherapy for breast cancer
Lekander M, Furst Cj, Rostein S, Blomgren H, Fredrikson M
ACTA ONCOLOGICA 1996;35(1):31-7

Lekander M, Furst Cj, Rotstein S, Blomgren H, Fredrikson M

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