Christian Riedel

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

I am a group leader at the Integrated Cardio Metabolic Center (ICMC) and
Department of Biosciences and Nutrition. My lab works on the regulation of
aging and age-related diseases.
Please follow the following links to our lab websites for more information:
https://ki.se/en/bionut/christian-riedel-group [1]
http://riedellab.org [2]
[1] https://ki.se/en/bionut/christian-riedel-group
[2] http://riedellab.org

Artiklar

Journal article: CELL STRESS. 2023;7(12):105-111

A versatile method for the identification of senolytic compounds.

Annunziata C; Castoldi F; Jan S; Ang HX; Ristovska M; Melini S; Welch R; Riedel CG; Pietrocola F
Journal article: DEVELOPMENT. 2023;150(21):dev201755

SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans.

Robert VJ; Caron M; Gely L; Adrait A; Pakulska V; Couté Y; Chevalier M; Riedel CG; Bedet C; Palladino F
Article: AGING-US. 2023;15(12):5240-5265

Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis.

Salignon J; Faridani OR; Miliotis T; Janssens GE; Chen P; Zarrouki B; Sandberg R; Davidsson P; Riedel CG
Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2023;78(1):158-166

Beyond Chronological Age: A Multidimensional Approach to Survival Prediction in Older Adults.

Salignon J; Rizzuto D; Calderón-Larrañaga A; Zucchelli A; Fratiglioni L; Riedel CG; Vetrano DL
Article: AGING-US. 2022;14(2):530-543

Meeting Report: Aging Research and Drug Discovery

Meron E; Thaysen M; Angeli S; Antebi A; Barzilai N; Baur JA; Bekker-Jensen S; Birkisdottir M; Bischof E; Bruening J; Brunet A; Buchwalter A; Cabreiro F; Cai S; Chen BH; Ermolaeva M; Ewald CY; Ferrucci L; Florian MC; Fortney K; Freund A; Georgievskaya A; Gladyshev VN; Glass D; Golato T; Gorbunova V; Hoejimakers J; Houtkooper RH; Jager S; Jaksch F; Janssens G; Jensen MB; Kaeberlein M; Karsenty G; de Keizer P; Kennedy B; Kirkland JL; Kjaer M; Kroemer G; Lee K-F; Lemaitre J-M; Liaskos D; Longo VD; Lu Y-X; MacArthur MR; Maier AB; Manakanatas C; Mitchell SJ; Moskalev A; Niedernhofer L; Ozerov I; Partridge L; Passegue E; Petr MA; Peyer J; Radenkovic D; Rando TA; Rattan S; Riedel CG; Rudolph L; Ai R; Serrano M; Schumacher B; Sinclair DA; Smith R; Suh Y; Taub P; Trapp A; Trendelenburg A-U; Valenzano DR; Verburgh K; Verdin E; Vijg J; Westendorp RGJ; Zonari A; Bakula D; Zhavoronkov A; Scheibye-Knudsen M
Article: MOLECULAR METABOLISM. 2021;54:101329

An inhibitor-mediated beta-cell dedifferentiation model reveals distinct roles for FoxO1 in glucagon repression and insulin maturation.

Casteels T; Zhang Y; Frogne T; Sturtzel C; Lardeau C-H; Sen I; Liu X; Hong S; Pauler FM; Penz T; Brandstetter M; Barbieux C; Berishvili E; Heuser T; Bock C; Riedel CG; Meyer D; Distel M; Hecksher-Sørensen J; Li J; Kubicek S
Article: CURRENT PROTOCOLS. 2021;1(7):e187

Chromatin Immunoprecipitation and Sequencing (ChIP-seq) Optimized for Application in Caenorhabditis elegans.

Sen I; Kavšek A; Riedel CG
Article: AGING-US. 2020;12(24):24484-24503

ARDD 2020: from aging mechanisms to interventions.

Mkrtchyan GV; Abdelmohsen K; Andreux P; Bagdonaite I; Barzilai N; Brunak S; Cabreiro F; de Cabo R; Campisi J; Cuervo AM; Demaria M; Ewald CY; Fang EF; Faragher R; Ferrucci L; Freund A; Silva-García CG; Georgievskaya A; Gladyshev VN; Glass DJ; Gorbunova V; de Grey A; He W-W; Hoeijmakers J; Hoffmann E; Horvath S; Houtkooper RH; Jensen MK; Jensen MB; Kane A; Kassem M; de Keizer P; Kennedy B; Karsenty G; Lamming DW; Lee K-F; MacAulay N; Mamoshina P; Mellon J; Molenaars M; Moskalev A; Mund A; Niedernhofer L; Osborne B; Pak HH; Parkhitko A; Raimundo N; Rando TA; Rasmussen LJ; Reis C; Riedel CG; Franco-Romero A; Schumacher B; Sinclair DA; Suh Y; Taub PR; Toiber D; Treebak JT; Valenzano DR; Verdin E; Vijg J; Young S; Zhang L; Bakula D; Zhavoronkov A; Scheibye-Knudsen M
Article: CURRENT PROTOCOLS IN PROTEIN SCIENCE. 2020;102(1):e114

Histone Purification Combined with High-Resolution Mass Spectrometry to Examine Histone Post-Translational Modifications and Histone Variants in Caenorhabditis elegans.

Millan-Ariño L; Yuan Z-F; Oomen ME; Brandenburg S; Chernobrovkin A; Salignon J; Körner L; Zubarev RA; Garcia BA; Riedel CG
Article: NATURE COMMUNICATIONS. 2020;11(1):138

DAF-16/FOXO requires Protein Phosphatase 4 to initiate transcription of stress resistance and longevity promoting genes.

Sen I; Zhou X; Chernobrovkin A; Puerta-Cavanzo N; Kanno T; Salignon J; Stoehr A; Lin X-X; Baskaner B; Brandenburg S; Björkegren C; Zubarev RA; Riedel CG
Article: CELL REPORTS. 2019;27(2):467-480.e6

Transcriptomics-Based Screening Identifies Pharmacological Inhibition of Hsp90 as a Means to Defer Aging.

Janssens GE; Lin X-X; Millan-Ariño L; Kavšek A; Sen I; Seinstra RI; Stroustrup N; Nollen EAA; Riedel CG
Article: NATURE COMMUNICATIONS. 2018;9(1):4400

DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity.

Lin X-X; Sen I; Janssens GE; Zhou X; Fonslow BR; Edgar D; Stroustrup N; Swoboda P; Yates JR; Ruvkun G; Riedel CG
Article: CELL METABOLISM. 2015;22(1):151-163

The Deubiquitylase MATH-33 Controls DAF-16 Stability and Function in Metabolism and Longevity.

Heimbucher T; Liu Z; Bossard C; McCloskey R; Carrano AC; Riedel CG; Tanasa B; Klammt C; Fonslow BR; Riera CE; Lillemeier BF; Kemphues K; Yates JR; O'Shea C; Hunter T; Dillin A
Article: NATURE CELL BIOLOGY. 2013;15(5):491-501

DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity.

Riedel CG; Dowen RH; Lourenco GF; Kirienko NV; Heimbucher T; West JA; Bowman SK; Kingston RE; Dillin A; Asara JM; Ruvkun G
Article: CURRENT BIOLOGY. 2012;22(10):881-890

The Caenorhabditis elegans RDE-10/RDE-11 complex regulates RNAi by promoting secondary siRNA amplification.

Zhang C; Montgomery TA; Fischer SEJ; Garcia SMDA; Riedel CG; Fahlgren N; Sullivan CM; Carrington JC; Ruvkun G
Article: GENES & DEVELOPMENT. 2011;25(19):2079-2092

The Caenorhabditis elegans SOMI-1 zinc finger protein and SWI/SNF promote regulation of development by the mir-84 microRNA.

Hayes GD; Riedel CG; Ruvkun G
Article: PLOS GENETICS. 2011;7(9):e1002235

The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO.

Rizki G; Iwata TN; Li J; Riedel CG; Picard CL; Jan M; Murphy CT; Lee SS
Article: CELL CYCLE. 2010;9(20):4048-4049

Toward the mechanisms preventing merotelic kinetochore-microtubule attachments.

Riedel CG
Article: CELL CYCLE. 2010;9(13):2657-2662

Casein kinase 1 is required for efficient removal of Rec8 during meiosis I.

Rumpf C; Cipak L; Dudas A; Benko Z; Pozgajova M; Riedel CG; Ammerer G; Mechtler K; Gregan J
Article: NATURE. 2009;459(7250):1079-1U60

A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants.

Curran SP; Wu X; Riedel CG; Ruvkun G
Article: CURRENT BIOLOGY. 2007;17(14):1190-1200

The kinetochore proteins Pcs1 and Mde4 and heterochromatin are required to prevent merotelic orientation.

Gregan J; Riedel CG; Pidoux AL; Katou Y; Rumpf C; Schleiffer A; Kearsey SE; Shirahige K; Allshire RC; Nasmyth K
Article: NATURE PROTOCOLS. 2007;2(5):1145-1151

Tandem affinity purification of functional TAP-tagged proteins from human cells.

Gregan J; Riedel CG; Petronczki M; Cipak L; Rumpf C; Poser I; Buchholz F; Mechtler K; Nasmyth K
Article: NATURE. 2006;441(7089):53-61

Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I.

Riedel CG; Katis VL; Katou Y; Mori S; Itoh T; Helmhart W; Gálová M; Petronczki M; Gregan J; Cetin B; Mudrak I; Ogris E; Mechtler K; Pelletier L; Buchholz F; Shirahige K; Nasmyth K
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2005;280(45):37846-37852

Differential requirement for phospholipase D/Spo14 and its novel interactor Sma1 for regulation of exocytotic vesicle fusion in yeast meiosis.

Riedel CG; Mazza M; Maier P; Körner R; Knop M
Article: TRENDS IN BIOCHEMICAL SCIENCES. 2004;29(8):389-392

Is chromatin remodeling required to build sister-chromatid cohesion?

Riedel CG; Gregan J; Gruber S; Nasmyth K
Article: BIOTECHNIQUES. 2002;33(3):592-602

Improved version of the red fluorescent protein (drFP583/DsRed/RFP).

Knop M; Barr F; Riedel CG; Heckel T; Reichel C
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Alla övriga publikationer

Preprint: 2023;bioRxiv

Cactus: a user-friendly and reproducible ATAC-Seq and mRNA-Seq analysis pipeline for data preprocessing, differential analysis, and enrichment analysis

Jérôme S; Millan-Ariño L; Garcia M; Riedel C
Preprint: BIORXIV. 2023;BIORXIV

The chromatin factors SET-26 and HCF-1 oppose the histone deacetylase HDA-1 in longevity and gene regulation in C. elegans.

Emerson FJ; Chiu C; Lin LY; Riedel CG; Zhu M; Lee SS
Preprint: 2022;bioRxiv

A multiparametric anti-aging CRISPR screen uncovers a role for BAF in protein translation

Breusegem SY; Houghton J; Romero-Bueno R; Fragoso-Luna A; Kentistou KA; Ong KK; Janssen AFJ; Bright NA; Riedel CG; Perry JRB; Askjaer P; Larrieu D
Review: CURRENT GENOMICS. 2018;19(6):464-482

Regulation of Age-related Decline by Transcription Factors and Their Crosstalk with the Epigenome.

Zhou X; Sen I; Lin X-X; Riedel CG
Book chapter: 2017;p. 95-116

Chapter 4 ATP-Dependent Chromatin Remodeling: From Development to Disease

Lezzerini M; Riedel CG
Other: CELL CYCLE. 2010;9(20):4048-4049

Toward the mechanisms preventing merotelic kinetochore-microtubule attachments.

Riedel CG

Forskningsbidrag

Discovery of new chromatin-related mechanisms that delay or prevent aging

Swedish Research Council

1 January 2024 - 31 December 2027
Molecular Profiling and Novel Treatment Strategies of Vascular Ageing in Chronic Kidney Disease

Swedish Research Council

1 January 2022 - 31 December 2024
New mechanistic insights into aging regulation by the transcription factor DAF-16/FOXO

Swedish Research Council

1 January 2020 - 31 December 2023
Disentangling complexity of health in aging: A new research environment to pave the road for individualized medicine

Swedish Research Council

1 December 2017 - 31 December 2022
Regulation of aging by DAF-16/FOXO, its cofactors, and the chromatin landscape

Swedish Research Council

1 January 2016 - 31 December 2019
Molecular mechanisms of longevity control

International Human Frontier Science Program Organization

1 May 2008 - 30 April 2011

Anställningar

Senior Forskare, Medicin, Huddinge, Karolinska Institutet, 2024-
Professor, Chair of Nutritional Physiology, Faculty of Lifesciences, University of Bayreuth, 2023-
Senior Forskare, Biovetenskaper och näringslära, Karolinska Institutet, 2022-2024
Assistant Professor, European Research Institute for the Biology of Ageing, University Medical Center Groningen, 2013-2015
Postdoctoral Fellow, Dept of Molecular Biology, Massachusetts General Hospital, 2007-2012

Examina och utbildning

Molecular Biology, Research Institute of Molecular Pathology, 2006
Biochemistry, University of Tübingen, 2001

Om mig

Artiklar

Alla övriga publikationer

Forskningsbidrag

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI