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Codon optimization and improved delivery/immunization regimen enhance the immune response against wild-type and drug-resistant HIV-1 reverse transcriptase, preserving its Th2-polarity.
Latanova A, Petkov S, Kilpelainen A, Jansons J, Latyshev O, Kuzmenko Y, et al
Sci Rep 2018 May;8(1):8078

HIVIS-DNA or HIVISopt-DNA priming followed by CMDR vaccinia-based boosts induce both humoral and cellular murine immune responses to HIV.
Hinkula J, Petkov S, Ljungberg K, Hallengärd D, Bråve A, Isaguliants M, et al
Heliyon 2017 Jun;3(6):e00339

Preferential Targeting of Conserved Gag Regions after Vaccination with a Heterologous DNA Prime-Modified Vaccinia Virus Ankara Boost HIV-1 Vaccine Regimen.
Bauer A, Podola L, Mann P, Missanga M, Haule A, Sudi L, et al
J. Virol. 2017 09;91(18):

Immunization with HIV-1 envelope T20-encoding DNA vaccines elicits cross-clade neutralizing antibody responses.
Stenler S, Lundin K, Hansen L, Petkov S, Mozafari N, Isaguliants M, et al
Hum Vaccin Immunother 2017 12;13(12):2849-2858

Three-Year Durability of Immune Responses Induced by HIV-DNA and HIV-Modified Vaccinia Virus Ankara and Effect of a Late HIV-Modified Vaccinia Virus Ankara Boost in Tanzanian Volunteers.
Joachim A, Munseri P, Nilsson C, Bakari M, Aboud S, Lyamuya E, et al
AIDS Res. Hum. Retroviruses 2017 08;33(8):880-888

Early antiretroviral therapy in children perinatally infected with HIV: a unique opportunity to implement immunotherapeutic approaches to prolong viral remission.
Klein N, Palma P, Luzuriaga K, Pahwa S, Nastouli E, Gibb D, et al
Lancet Infect Dis 2015 Sep;15(9):1108-1114

HIV-DNA Given with or without Intradermal Electroporation Is Safe and Highly Immunogenic in Healthy Swedish HIV-1 DNA/MVA Vaccinees: A Phase I Randomized Trial.
Nilsson C, Hejdeman B, Godoy-Ramirez K, Tecleab T, Scarlatti G, Bråve A, et al
PLoS ONE 2015 ;10(6):e0131748

Potent functional antibody responses elicited by HIV-I DNA priming and boosting with heterologous HIV-1 recombinant MVA in healthy Tanzanian adults.
Joachim A, Nilsson C, Aboud S, Bakari M, Lyamuya E, Robb M, et al
PLoS ONE 2015 ;10(4):e0118486

Immunotherapy with an HIV-DNA Vaccine in Children and Adults.
Palma P, Gudmundsdotter L, Finocchi A, Eriksson L, Mora N, Santilli V, et al
Vaccines (Basel) 2014 Jul;2(3):563-80

Broad and potent cellular and humoral immune responses after a second late HIV-modified vaccinia virus ankara vaccination in HIV-DNA-primed and HIV-modified vaccinia virus Ankara-boosted Swedish vaccinees.
Nilsson C, Godoy-Ramirez K, Hejdeman B, Bråve A, Gudmundsdotter L, Hallengärd D, et al
AIDS Res. Hum. Retroviruses 2014 Mar;30(3):299-311

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