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Publikationer

Aetiology of lower respiratory tract infection in adults in primary care: a prospective study in 11 European countries
Grace Consortium, Ieven M, Coenen S, Loens K, Lammens C, Coenjaerts F, et al
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2018;():-

Detection of human disease conditions by single-cell morpho-rheological phenotyping of blood
Toepfner N, Herold C, Otto O, Rosendahl P, Jacobi A, Kräter M, et al
eLife 2018;7():-

Immunomodulatory Effects of Pneumococcal Extracellular Vesicles on Cellular and Humoral Host Defenses
Codemo M, Muschiol S, Iovino F, Nannapaneni P, Plant L, Wai Sn, et al
mBio 2018;9(2):-

Receptor Blockade: A Novel Approach to Protect the Brain From Pneumococcal Invasion
Iovino F, Thorsdottir S, Henriques-normark B
The Journal of infectious diseases 2018;():-

Reply to Theilacker et al
Naucler P, Galanis I, Morfeldt E, Darenberg J, Örtqvist Å, Henriques-normark B
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2018;66(10):1642-1643

Separation of pathogenic bacteria by chain length
Beech Jp, Ho Bd, Garriss G, Oliveira V, Henriques-normark B, Tegenfeldt Jo
Analytica chimica acta 2018;1000():223-231

Analysis of IAV Replication and Co-infection Dynamics by a Versatile RNA Viral Genome Labeling Method
Dou D, Hernández-neuta I, Wang H, Östbye H, Qian X, Thiele S, et al
Cell reports 2017;20(1):251-263

Coeliac disease and invasive pneumococcal disease: a population-based cohort study
Röckert Tjernberg A, Bonnedahl J, Inghammar M, Egesten A, Kahlmeter G, Nauclér P, et al
Epidemiology and infection 2017;145(6):1203-1209

Comparison of the Impact of Pneumococcal Conjugate Vaccine 10 or Pneumococcal Conjugate Vaccine 13 on Invasive Pneumococcal Disease in Equivalent Populations
Naucler P, Galanis I, Morfeldt E, Darenberg J, Örtqvist Å, Henriques-normark B
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2017;65(11):1780-1789

Comparison of the Impact of Pneumococcal Conjugate Vaccine 10 or Pneumococcal Conjugate Vaccine 13 on Invasive Pneumococcal Disease in Equivalent Populations
Naucler P, Galanis I, Morfeldt E, Darenberg J, Ortqvist A, Henriques-normark B
CLINICAL INFECTIOUS DISEASES 2017;65(11):1813-1818

Effect of high-valency pneumococcal conjugate vaccines on invasive pneumococcal disease in children in SpIDnet countries: an observational multicentre study
Spidnet Group, Savulescu C, Krizova P, Lepoutre A, Mereckiene J, Vestrheim Df, et al
The Lancet. Respiratory medicine 2017;5(8):648-656

pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion
Iovino F, Engelen-lee Jy, Brouwer M, Van De Beek D, Van Der Ende A, Valls Seron M, et al
The Journal of experimental medicine 2017;214(6):1619-1630

Structure of the competence pilus major pilin ComGC in Streptococcus pneumoniae
Muschiol S, Erlendsson S, Aschtgen Ms, Oliveira V, Schmieder P, De Lichtenberg C, et al
The Journal of biological chemistry 2017;292(34):14134-14146

The Pneumocell-study: Vaccination of IgG1- and IgG2-deficient patients with Prevnar13
Zangenah S, Björkhem-bergman L, Norlin Ac, Hansen S, Lindqvist L, Henriques-normark B, et al
Vaccine 2017;35(20):2654-2660

Vitamin D Promotes Pneumococcal Killing and Modulates Inflammatory Responses in Primary Human Neutrophils
Subramanian K, Bergman P, Henriques-normark B
Journal of innate immunity 2017;9(4):375-386

Cinobufagin Modulates Human Innate Immune Responses and Triggers Antibacterial Activity
Xie S, Spelmink L, Codemo M, Subramanian K, Pütsep K, Henriques-normark B, et al
PloS one 2016;11(8):e0160734-

Effects of PCV7 and PCV13 on invasive pneumococcal disease and carriage in Stockholm, Sweden
Galanis I, Lindstrand A, Darenberg J, Browall S, Nannapaneni P, Sjöström K, et al
The European respiratory journal 2016;47(4):1208-18

How Does Streptococcus pneumoniae Invade the Brain?
Iovino F, Seinen J, Henriques-normark B, Van Dijl Jm
Trends in microbiology 2016;24(4):307-315

Impact of AmpC Derepression on Fitness and Virulence: the Mechanism or the Pathway?
Pérez-gallego M, Torrens G, Castillo-vera J, Moya B, Zamorano L, Cabot G, et al
mBio 2016;7(5):-

Influenza A Virus Infection Predisposes Hosts to Secondary Infection with Different Streptococcus pneumoniae Serotypes with Similar Outcome but Serotype-Specific Manifestation
Sharma-chawla N, Sender V, Kershaw O, Gruber Ad, Volckmar J, Henriques-normark B, et al
Infection and immunity 2016;84(12):3445-3457

Lung epithelium and myeloid cells cooperate to clear acute pneumococcal infection
Dudek M, Puttur F, Arnold-schrauf C, Kühl Aa, Holzmann B, Henriques-normark B, et al
Mucosal immunology 2016;9(5):1288-302

lytA-based identification methods can misidentify Streptococcus pneumoniae
Simões As, Tavares Da, Rolo D, Ardanuy C, Goossens H, Henriques-normark B, et al
Diagnostic microbiology and infectious disease 2016;85(2):141-8

N-acetylglucosamine-Mediated Expression of nagA and nagB in Streptococcus pneumoniae
Afzal M, Shafeeq S, Manzoor I, Henriques-normark B, Kuipers Op
Frontiers in cellular and infection microbiology 2016;6():158-

Pneumococcal Carriage in Children under Five Years in Uganda-Will Present Pneumococcal Conjugate Vaccines Be Appropriate?
Lindstrand A, Kalyango J, Alfvén T, Darenberg J, Kadobera D, Bwanga F, et al
PloS one 2016;11(11):e0166018-

Pneumococcal meningitis is promoted by single cocci expressing pilus adhesin RrgA
Iovino F, Hammarlof Dl, Garriss G, Brovall S, Nannapaneni P, Henriques-normark B
JOURNAL OF CLINICAL INVESTIGATION 2016;126(8):2821-6

Streptococcus pneumoniae Senses a Human-like Sialic Acid Profile via the Response Regulator CiaR
Hentrich K, Löfling J, Pathak A, Nizet V, Varki A, Henriques-normark B
Cell host & microbe 2016;20(3):307-317

The BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation; structural insights into pneumococcal biofilm formation
Schulte T, Mikaelsson C, Beaussart A, Kikhney A, Deshmukh M, Wolniak S, et al
Scientific reports 2016;6():32371-

The crystal structure of the major pneumococcal autolysin LytA in complex with a large peptidoglycan fragment reveals the pivotal role of glycans for lytic activity
Sandalova T, Lee M, Henriques-normark B, Hesek D, Mobashery S, Mellroth P, et al
Molecular microbiology 2016;101(6):954-67

Toll-Like Receptor 3/TRIF-Dependent IL-12p70 Secretion Mediated by Streptococcus pneumoniae RNA and Its Priming by Influenza A Virus Coinfection in Human Dendritic Cells
Spelmink L, Sender V, Hentrich K, Kuri T, Plant L, Henriques-normark B
mBio 2016;7(2):e00168-16

Unaltered pneumococcal carriage prevalence due to expansion of non-vaccine types of low invasive potential 8years after vaccine introduction in Stockholm, Sweden
Lindstrand A, Galanis I, Darenberg J, Morfeldt E, Naucler P, Blennow M, et al
Vaccine 2016;34(38):4565-4571

Variation in Inflammatory Response during Pneumococcal Infection Is Influenced by Host-Pathogen Interactions but Associated with Animal Survival
Jonczyk Ms, Escudero L, Sylvius N, Norman M, Henriques-normark B, Andrew Pw
Infection and immunity 2016;84(4):894-905

BCG Skin Infection Triggers IL-1R-MyD88-Dependent Migration of EpCAMlow CD11bhigh Skin Dendritic cells to Draining Lymph Node During CD4+ T-Cell Priming
Bollampalli Vp, Harumi Yamashiro L, Feng X, Bierschenk D, Gao Y, Blom H, et al
PLoS pathogens 2015;11(10):e1005206-

Reply to Arends and Harkisoen
Linnér A, Sjölin J, Darenberg J, Henriques-normark B, Norrby-teglund A
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2015;60(2):324-5

Respiratory viruses associated with community-acquired pneumonia in children: matched case-control study
Rhedin S, Lindstrand A, Hjelmgren A, Ryd-rinder M, Öhrmalm L, Tolfvenstam T, et al
Thorax 2015;70(9):847-53

Streptococcal M1 Strikes by Neutralizing Cathelicidins
Henriques-normark B, Normark S
Cell host & microbe 2015;18(4):390-1

Transcriptional profiling of UlaR-regulated genes in Streptococcus pneumoniae
Shafeeq S, Afzal M, Henriques-normark B, Kuipers Op
Genomics data 2015;4():57-9

UlaR activates expression of the ula operon in Streptococcus pneumoniae in the presence of ascorbic acid
Afzal M, Shafeeq S, Henriques-normark B, Kuipers Op
Microbiology (Reading, England) 2015;161(Pt 1):41-9

Uptake of extracellular DNA: competence induced pili in natural transformation of Streptococcus pneumoniae
Muschiol S, Balaban M, Normark S, Henriques-normark B
BioEssays : news and reviews in molecular, cellular and developmental biology 2015;37(4):426-35

Adult zebrafish model for pneumococcal pathogenesis
Saralahti A, Piippo H, Parikka M, Henriques-normark B, Ramet M, Rounioja S
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 2014;42(2):345-53

Bacterial vaccines and antibiotic resistance
Henriques-normark B, Normark S
Upsala journal of medical sciences 2014;119(2):205-8

Clinical efficacy of polyspecific intravenous immunoglobulin therapy in patients with streptococcal toxic shock syndrome: a comparative observational study
Linnér A, Darenberg J, Sjölin J, Henriques-normark B, Norrby-teglund A
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2014;59(6):851-7

Clinical manifestations of invasive pneumococcal disease by vaccine and non-vaccine types
Browall S, Backhaus E, Naucler P, Galanis I, Sjöström K, Karlsson D, et al
The European respiratory journal 2014;44(6):1646-57

Clinical utility of PCR for common viruses in acute respiratory illness
Rhedin S, Lindstrand A, Rotzén-Östlund M, Tolfvenstam T, Ohrmalm L, Rinder Mr, et al
Pediatrics 2014;133(3):e538-45

Emergence of Hypervirulent Mutants Resistant to Early Clearance During Systemic Serotype 1 Pneumococcal Infection in Mice and Humans
Syk A, Norman M, Fernebro J, Gallotta M, Farmand S, Sandgren A, et al
JOURNAL OF INFECTIOUS DISEASES 2014;210(1):4-13

Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences
Nasser W, Beres Sb, Olsen Rj, Dean Ma, Rice Ka, Long W, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2014;111(17):E1768-76

Human isolates of Listeria monocytogenes in Sweden during half a century (1958-2010)
Lopez-valladares G, Tham W, Parihar Vs, Helmersson S, Andersson B, Ivarsson S, et al
Epidemiology and infection 2014;142(11):2251-60

Improvement of CRB-65 as a prognostic tool in adult patients with community-acquired pneumonia
Dwyer R, Hedlund J, Henriques-normark B, Kalin M
BMJ open respiratory research 2014;1(1):e000038-

Intraclonal Variations Among Streptococcus pneumoniae Isolates Influence the Likelihood of Invasive Disease in Children
Browall S, Norman M, Tangrot J, Galanis I, Sjostrom K, Dagerhamn J, et al
JOURNAL OF INFECTIOUS DISEASES 2014;209(3):377-88

Prevalence of community-acquired bacteraemia in Guinea-Bissau: an observational study
Isendahl J, Manjuba C, Rodrigues A, Xu W, Henriques-normark B, Giske Cg, et al
BMC infectious diseases 2014;14():3859-

Secretion of a pneumococcal type II secretion system pilus correlates with DNA uptake during transformation
Balaban M, Battig P, Muschiol S, Tirier Sm, Wartha F, Normark S, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2014;111(7):E758-65

Sinusitis and pneumonia hospitalization after introduction of pneumococcal conjugate vaccine
Lindstrand A, Bennet R, Galanis I, Blennow M, Ask Ls, Dennison Sh, et al
Pediatrics 2014;134(6):e1528-36

Structural and Functional Insights into Peptidoglycan Access for the Lytic Amidase LytA of Streptococcus pneumoniae
Mellroth P, Sandalova T, Kikhney A, Vilaplana F, Hesek D, Lee M, et al
MBIO 2014;5(1):e01120-13

The basic keratin 10-binding domain of the virulence-associated pneumococcal serine-rich protein PsrP adopts a novel MSCRAMM fold
Schulte T, Löfling J, Mikaelsson C, Kikhney A, Hentrich K, Diamante A, et al
Open biology 2014;4():130090-

Comprehensive Antigen Screening Identifies Moraxella catarrhalis Proteins That Induce Protection in a Mouse Pulmonary Clearance Model
Smidt M, Battig P, Verhaegh Sjc, Niebisch A, Hanner M, Selak S, et al
PLOS ONE 2013;8(5):e64422-

Contribution of host, bacterial factors and antibiotic treatment to mortality in adult patients with bacteraemic pneumococcal pneumonia
Naucler P, Darenberg J, Morfeldt E, Ortqvist A, Henriques Normark B
Thorax 2013;68(6):571-9

Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection
Croucher Nj, Mitchell Am, Gould Ka, Inverarity D, Barquist L, Feltwell T, et al
PLOS GENETICS 2013;9(10):e1003868-

Focal targeting by human beta-defensin 2 disrupts localized virulence factor assembly sites in Enterococcus faecalis
Kandaswamy K, Liew Th, Wang Cy, Huston-warren E, Meyer-hoffert U, Hultenby K, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2013;110(50):20230-5

Immunomodulatory effects of vitamin D on innate and adaptive immune responses to Streptococcus pneumoniae
Olliver M, Spelmink L, Hiew J, Meyer-hoffert U, Henriques-normark B, Bergman P
The Journal of infectious diseases 2013;208(9):1474-81

Increased incidence of invasive group A streptococcal infections in Sweden, January 2012-February 2013
Darenberg J, Henriques-normark B, Lepp T, Tegmark-wisell K, Tegnell A, Widgren K
EUROSURVEILLANCE 2013;18(14):20443-

Influenza A virus-mediated priming enhances cytokine secretion by human dendritic cells infected with Streptococcus pneumoniae
Kuri T, Sörensen As, Thomas S, Karlsson Hedestam Gb, Normark S, Henriques-normark B, et al
Cellular microbiology 2013;15(8):1385-400

Low rate of pneumococci non-susceptible to penicillin in healthy Swedish toddlers
Skovbjerg S, Söderström A, Hynsjö L, Normark Bh, Ekdahl K, Åhrén C
Scandinavian journal of infectious diseases 2013;45(4):279-84

Oral bacterial community dynamics in paediatric patients with malignancies in relation to chemotherapy-related oral mucositis: a prospective study
Ye Y, Carlsson G, Agholme Mb, Wilson Ja, Roos A, Henriques-normark B, et al
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2013;19(12):E559-67

Pilin and Sortase Residues Critical for Endocarditis- and BiofilmAssociated Pilus Biogenesis in Enterococcus faecalis
Nielsen Hv, Flores-mireles Al, Kau Al, Kline Ka, Pinkner Js, Neiers F, et al
JOURNAL OF BACTERIOLOGY 2013;195(19):4484-95

The pneumococcus: epidemiology, microbiology, and pathogenesis
Henriques-normark B, Tuomanen Ei
Cold Spring Harbor perspectives in medicine 2013;3(7):-

TLR7 Contributes to the Rapid Progression but Not to the Overall Fatal Outcome of Secondary Pneumococcal Disease following Influenza A Virus Infection
Stegemann-koniszewski S, Gereke M, Orrskog S, Lienenklaus S, Pasche B, Bader Sr, et al
JOURNAL OF INNATE IMMUNITY 2013;5(1):84-96

Defense of zebrafish embryos against Streptococcus pneumoniae infection is dependent on the phagocytic activity of leukocytes
Rounioja S, Saralahti A, Rantala L, Parikka M, Henriques-normark B, Silvennoinen O, et al
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 2012;36(2):342-8

Description of macrolide-resistant and potential virulent clones of Streptococcus pyogenes causing asymptomatic colonization during 2000-2006 in the Lisbon area
Pires R, Rolo D, Morais A, Brito-avo A, Johansson C, Henriques-normark B, et al
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES 2012;31(5):849-57

LytA, Major Autolysin of Streptococcus pneumoniae, Requires Access to Nascent Peptidoglycan
Mellroth P, Daniels R, Eberhardt A, Ronnlund D, Blom H, Widengren J, et al
JOURNAL OF BIOLOGICAL CHEMISTRY 2012;287(14):11018-29

Pilus adhesin RrgA interacts with complement receptor 3, thereby affecting macrophage function and systemic pneumococcal disease
Orrskog S, Rounioja S, Spadafina T, Gallotta M, Norman M, Hentrich K, et al
mBio 2012;4(1):e00535-12

The Metal Ion-Dependent Adhesion Site Motif of the Enterococcus faecalis EbpA Pilin Mediates Pilus Function in Catheter-Associated Urinary Tract Infection
Nielsen Hv, Guiton Ps, Kline Ka, Port Gc, Pinkner Js, Neiers F, et al
MBIO 2012;3(4):e00177-12

A case of diphtheria in Sweden, October 2011
Fredlund H, Noren T, Lepp T, Morfeldt E, Normark Bh
EUROSURVEILLANCE 2011;16(50):10-11

A case of diphtheria in Sweden, October 2011
Fredlund H, Norén T, Lepp T, Morfeldt E, Henriques Normark B
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2011;16(50):20038-

Cellular interactions by LPxTG-anchored pneumococcal adhesins and their streptococcal homologues
Lofling J, Vimberg V, Battig P, Henriques-normark B
CELLULAR MICROBIOLOGY 2011;13(2):186-97

Control of intestinal Nod2-mediated peptidoglycan recognition by epithelium-associated lymphocytes
Duerr Cu, Salzman Nh, Dupont A, Szabo A, Normark Bh, Normark S, et al
MUCOSAL IMMUNOLOGY 2011;4(3):325-34

Effects of Streptococcus pneumoniae Strain Background on Complement Resistance
Hyams C, Opel S, Hanage W, Yuste J, Bax K, Henriques-normark B, et al
PLOS ONE 2011;6(10):e24581-

Human Monocytes Promote Th1 and Th17 Responses to Streptococcus pneumoniae
Olliver M, Hiew J, Mellroth P, Henriques-normark B, Bergman P
INFECTION AND IMMUNITY 2011;79(10):4210-7

Identification of a Family of Effectors Secreted by the Type III Secretion System That Are Conserved in Pathogenic Chlamydiae
Muschiol S, Boncompain G, Vromman F, Dehoux P, Normark S, Henriques-normark B, et al
INFECTION AND IMMUNITY 2011;79(2):571-80

Impaired Release of Antimicrobial Peptides into Nasal Fluid of Hyper-IgE and CVID Patients
Cederlund A, Olliver M, Rekha Rs, Lindh M, Lindbom L, Normark S, et al
PLOS ONE 2011;6(12):e29316-

Improvement of CRB-65 as a prognostic scoring system in adult patients with bacteraemic pneumococcal pneumonia
Dwyer R, Hedlund J, Darenberg J, Henriques-normark B, Naucler P, Runesdotter S, et al
SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES 2011;43(6-7):448-55

Studies on the Antibacterial Effects of Statins - In Vitro and In Vivo
Bergman P, Linde C, Putsep K, Pohanka A, Normark S, Henriques-normark B, et al
PLOS ONE 2011;6(8):e24394-

Characterization of a Novel Murine Model of Staphylococcus saprophyticus Urinary Tract Infection Reveals Roles for Ssp and SdrI in Virulence
Kline Ka, Ingersoll Ma, Nielsen Hv, Sakinc T, Henriques-normark B, Gatermann S, et al
INFECTION AND IMMUNITY 2010;78(5):1943-51

Commensal pathogens, with a focus on Streptococcus pneumoniae, and interactions with the human host
Henriques-normark B, Normark S
EXPERIMENTAL CELL RESEARCH 2010;316(8):1408-14

Disulfide Bond Formation and Cysteine Exclusion in Gram-positive Bacteria
Daniels R, Mellroth P, Bernsel A, Neiers F, Normark S, Von Heijne G, et al
JOURNAL OF BIOLOGICAL CHEMISTRY 2010;285(5):3300-9

Influenza Enhances Susceptibility to Natural Acquisition of and Disease due to Streptococcus pneumoniae in Ferrets
Mccullers Ja, Mcauley Jl, Browall S, Iverson Ar, Boyd Kl, Normark Bh
JOURNAL OF INFECTIOUS DISEASES 2010;202(8):1287-95

Bacterial Adhesins in Host-Microbe Interactions
Kline Ka, Falker S, Dahlberg S, Normark S, Henriques-normark B
CELL HOST & MICROBE 2009;5(6):580-92

Clinical and Microbiological Characteristics of Severe Streptococcus pyogenes Disease in Europe
Strep-euro Study Grp, Luca-harari B, Darenberg J, Neal S, Siljander T, Strakova L, et al
JOURNAL OF CLINICAL MICROBIOLOGY 2009;47(4):1155-65

Clinical Isolates of Streptococcus pneumoniae Bind the Complement Inhibitor Cob-Binding Protein in a PspC Allele-Dependent Fashion
Dieudonne-vatran A, Krentz S, Blom Am, Meri S, Henriques-normark B, Riesbeck K, et al
JOURNAL OF IMMUNOLOGY 2009;182(12):7865-77

Cloning, expression, purification, crystallization and preliminary X-ray analysis of the pilus-associated sortase C from Streptococcus pneumoniae
Neiers F, Madhurantakam C, Falker S, Normark S, Henriques-normark B, Achour A
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 2009;:55-8

Increased Susceptibility for Superinfection with Streptococcus pneumoniae during Influenza Virus Infection Is Not Caused by TLR7-Mediated Lymphopenia
Stegemann S, Dahlberg S, Kroger A, Gereke M, Bruder D, Henriques-normark B, et al
PLOS ONE 2009;4(3):e4840-

Mechanism for Sortase Localization and the Role of Sortase Localization in Efficient Pilus Assembly in Enterococcus faecalis
Kline Ka, Kau Al, Chen Sl, Lim A, Pinkner Js, Rosch J, et al
JOURNAL OF BACTERIOLOGY 2009;191(10):3237-47

Pattern of Accessory Regions and Invasive Disease Potential in Streptococcus pneumoniae
Blomberg C, Dagerhamn J, Dahlberg S, Browall S, Fernebro J, Albiger B, et al
JOURNAL OF INFECTIOUS DISEASES 2009;199(7):1032-42

Resistance to bacitracin in Streptococcus pyogenes from oropharyngeal colonization and noninvasive infections in Portugal was caused by two clones of distinct virulence genotypes
Pires R, Rolo D, Mato R, De Almeida Jf, Johansson C, Henriques-normark B, et al
FEMS MICROBIOLOGY LETTERS 2009;296(2):235-40

Role Played by psrP-secY2A2 (Accessory Region 34) in the Invasive Disease Potential of Streptococcus pneumoniae Reply
Henriques-normark B
JOURNAL OF INFECTIOUS DISEASES 2009;200(7):1181-1182

Small molecule inhibitors of the Yersinia type III secretion system impair the development of Chlamydia after entry into host cells
Muschiol S, Normark S, Henriques-normark B, Subtil A
BMC MICROBIOLOGY 2009;:75-

Streptococcus pneumoniae evades human dendritic cell surveillance by pneumolysin expression
Littmann M, Albiger B, Frentzen A, Normark S, Henriques-normark B, Plant L
EMBO MOLECULAR MEDICINE 2009;1(4):211-22

The epidemiology of pneumococcal infections-The Swedish experience
Darenberg J, Normark Bh
VACCINE 2009;:G27-32

Two Crystal Structures of Pneumococcal Pilus Sortase C Provide Novel Insights into Catalysis and Substrate Specificity
Neiers F, Madhurantakam C, Falker S, Manzano C, Dessen A, Normark S, et al
JOURNAL OF MOLECULAR BIOLOGY 2009;393(3):704-16

An individual-based network model to evaluate interventions for controlling transmission
Karlsson D, Jansson A, Normark Bh, Nilsson P
BMC INFECTIOUS DISEASES 2008;:83-

Bacterial ligand of TLR2 signals Stat activation via induction of IRF1/2 and interferon-alpha production
Liljeroos M, Vuolteenaho R, Rounioja S, Henriques-normark B, Hallman M, Ojaniemi M
CELLULAR SIGNALLING 2008;20(10):1873-81

Characterization of Human Invasive Isolates of Listeria monocytogenes in Sweden 1986-2007
Parihar Vs, Lopez-valladares G, Danielsson-tham Ml, Peiris I, Helmersson S, Unemo M, et al
FOODBORNE PATHOGENS AND DISEASE 2008;5(6):755-61

Determination of accessory gene patterns predicts the same relatedness among strains of Streptococcus pneumoniae as sequencing of housekeeping genes does and represents a novel a approach in molecular epidemiology
Dagerhamn J, Blomberg C, Browall S, Sjostrom K, Morfeldt E, Henriques-normark B
JOURNAL OF CLINICAL MICROBIOLOGY 2008;46(3):863-8

Developmental switch of intestinal antimicrobial peptide expression
Menard S, Forster V, Lotz M, Gutle D, Duerr Cu, Gallo Rl, et al
JOURNAL OF EXPERIMENTAL MEDICINE 2008;205(1):183-93

Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies
Giefing C, Meinke Al, Hanner M, Henics T, Minh Db, Gelbmann D, et al
JOURNAL OF EXPERIMENTAL MEDICINE 2008;205(1):117-31

Effects of a large-scale introduction of the pneumococcal polysaccharide vaccine among elderly persons in Stockholm, Sweden
Spindler C, Hedlund J, Jasir A, Normark Bh, Ortqvist A
VACCINE 2008;26(43):5541-6

Epidemiology of severe Streptococcus pyogenes disease in Europe
Strep-euro Study Grp, Lamagni Tl, Darenberg J, Luca-harari B, Siljander T, Efstratiou A, et al
JOURNAL OF CLINICAL MICROBIOLOGY 2008;46(7):2359-67

ETosis : A Novel Cell Death Pathway
Wartha F, Henriques-normark B
SCIENCE SIGNALING 2008;1(21):pe25-

Identification of heparin/heparan sulfate interacting protein as a major broad-spectrum antimicrobial protein in lung and small intestine
Meyer-hoffert U, Hornef M, Henriques-normark B, Normark S, Andersson M, Putsep K
FASEB JOURNAL 2008;22(7):2427-34

INVASIVE CAPSULAR SEROTYPES OF STREPTOCOCCUS PNEUMONIAE ARE RELATIVELY RESISTANT TO COMPLEMENT COMPARED WITH NON-INVASIVE SEROTYPES
Hyams Cj, Opel S, Yuste J, Hanage Wp, Henriques-normark B, Wesier Jn, et al
THORAX 2008;:A52-A52

Lysogenic transfer of group A Streptococcus superantigen gene among streptococci
Vojtek I, Pirzada Za, Henriques-normark B, Mastny M, Janapatla Rp, Charpentier E
JOURNAL OF INFECTIOUS DISEASES 2008;197(2):225-34

Secreted enteric antimicrobial activity localises to the mucus surface layer
Meyer-hoffert U, Hornef Mw, Henriques-normark B, Axelsson Lg, Midtvedt T, Putsep K, et al
GUT 2008;57(6):764-71

Sortase-mediated assembly and surface topology of adhesive pneumococcal pili
Falker S, Nelson Al, Morfeldt E, Jonas K, Hultenby K, Ries J, et al
MOLECULAR MICROBIOLOGY 2008;70(3):595-607

Streptococcus pneumoniae contains 3 rlrA pilus variants that are clonally related
Moschioni M, Donati C, Muzzi A, Masignani V, Censini S, Hanage Wp, et al
JOURNAL OF INFECTIOUS DISEASES 2008;197(6):888-96

The capsule sensitizes Streptococcus pneumoniae to alpha-defensins human neutrophil proteins 1 to 3
Beiter K, Wartha F, Hurwitz R, Normark S, Zychlinsky A, Henriques-normark B
INFECTION AND IMMUNITY 2008;76(8):3710-6

The function and biological role of toll-like receptors in infectious diseases: an update
Hornef Mw, Henriques-normark B, Normark S
CURRENT OPINION IN INFECTIOUS DISEASES 2008;21(3):304-12

The influence of in vitro fitness defects on pneumococcal ability to colonize and to cause invasive disease
Fernebro J, Blomberg C, Morfeldt E, Wolf-watz H, Normark S, Normark Bh
BMC MICROBIOLOGY 2008;:65-

The rise and fall of bacterial clones: Streptococcus pneumoniae
Henriques-normark B, Blomberg C, Dagerhamn J, Battig P, Normark S
NATURE REVIEWS MICROBIOLOGY 2008;6(11):827-37

TLR7 triggered lymphopenia does not influence susceptibility to post-influenza pneumococcal infection
Stegemann S, Dahlberg S, Bruder D, Henriques-normark B, Gunzer M
WIENER KLINISCHE WOCHENSCHRIFT 2008;:148-149

Capsule and D-alanylated lipoteichoic acids protect Streptococcus pneumoniae against neutrophil extracellular traps
Wartha F, Beiter K, Albiger B, Fernebro J, Zychlinsky A, Normark S, et al
CELLULAR MICROBIOLOGY 2007;9(5):1162-71

Clonal success of piliated penicillin nonsusceptible pneumococci
Sjostrom K, Blomberg C, Fernebro J, Dagerhamn J, Morfeldt E, Barocchi Ma, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2007;104(31):12907-12

International quality assurance study for characterization of Streptococcus pyogenes
Strep-euro Study Grp, Int Streptococcus Reference Lab, Neal S, Beall B, Ekelund K, Henriques-normark B, et al
JOURNAL OF CLINICAL MICROBIOLOGY 2007;45(4):1175-9

Modeling the regulation of the competence-evoking quorum sensing network in Streptococcus pneumoniae
Karlsson D, Karlsson S, Gustafsson E, Normark Bh, Nilsson P
BIOSYSTEMS 2007;90(1):211-23

Molecular and clinical characteristics of invasive group A streptococcal infection in Sweden
Darenberg J, Luca-harari B, Jasir A, Sandgren A, Pettersson H, Schalen C, et al
CLINICAL INFECTIOUS DISEASES 2007;45(4):450-8

Neutrophil extracellular traps: casting the NET over pathogenesis
Wartha F, Beiter K, Normark S, Henriques-normark B
CURRENT OPINION IN MICROBIOLOGY 2007;10(1):52-6

PI3 kinase and Btk modulate the activity of IRF and Stat proteins in TLR2 signalling
Liljeroos M, Rounioja S, Vuolteenaho R, Henriques-normark B, Hallman M, Ojaniemi M
SCANDINAVIAN JOURNAL OF IMMUNOLOGY 2007;65(6):608-608

Role of the innate immune system in host defence against bacterial infections: focus on the Toll-like receptors
Albiger B, Dahlberg S, Henriques-normark B, Normark S
JOURNAL OF INTERNAL MEDICINE 2007;261(6):511-28

RrgA is a pilus-associated adhesin in Streptococcus pneumoniae
Nelson Al, Ries J, Bagnoli F, Dahlberg S, Falker S, Rounioja S, et al
MOLECULAR MICROBIOLOGY 2007;66(2):329-40

Small molecule inhibitors of type III secretion in Yersinia block the Chlamydia pneumoniae infection cycle
Bailey L, Gylfe A, Sundin C, Muschiol S, Elofsson M, Nordstrom P, et al
FEBS LETTERS 2007;581(4):587-95

Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection
Albiger B, Dahlberg S, Sandgren A, Wartha F, Beiter K, Katsuragi H, et al
CELLULAR MICROBIOLOGY 2007;9(3):633-44

Addition of a macrolide to a beta-lactam in bacteremic pneumococcal pneumonia
Dwyer R, Ortqvist A, Aufwerber E, Normark Bh, Marrie Tj, Mufson Ma, et al
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES 2006;25(8):518-21

An endonuclease allows Streptococcus pneumoniae to escape from neutrophil extracellular traps
Beiter K, Wartha F, Albiger B, Normark S, Zychlinsky A, Henriques-normark B
CURRENT BIOLOGY 2006;16(4):401-7

A pneumococcal pilus influences virulence and host inflammatory responses
Barocchi Ma, Rie J, Zogaj X, Hemsley C, Albiger B, Kanth A, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2006;103(8):2857-62

A small-molecule inhibitor of type III secretion inhibits different stages of the infectious cycle of Chlamydia trachomatis
Muschiol S, Bailey L, Gylfe A, Sundin C, Hultenby K, Bergstrom S, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2006;103(39):14566-71

Clonal and capsular types decide whether pneumococci will act as a primary or opportunistic pathogen
Sjostrom K, Spindler C, Ortqvist A, Kalin M, Sandgren A, Kuhlmann-berenzon S, et al
CLINICAL INFECTIOUS DISEASES 2006;42(4):451-9

Endocarditis and pericarditis complicating pneumococcal bacteraemia, with special reference to the adhesive abilities of pneumococci: results from a prospective study
Kan B, Ries J, Normark Bh, Chang Fy, Feldman C, Ko Wc, et al
CLINICAL MICROBIOLOGY AND INFECTION 2006;12(4):338-44

Penicillin-resistant pneumococci in Sweden 1997-2003: Increased multiresistance despite stable prevalence and decreased antibiotic use
Hogberg L, Ekdahl K, Sjostrom K, Olsson-liljequist B, Walder M, Melander E, et al
MICROBIAL DRUG RESISTANCE-MECHANISMS EPIDEMIOLOGY AND DISEASE 2006;12(1):16-22

Pneumococcal serotypes and virulence - Reply
Henriques-normark B
JOURNAL OF INFECTIOUS DISEASES 2006;193(3):477-478

The fallacies of hope: will we discover new antibiotics to combat pathogenic bacteria in time?
Vicente M, Hodgson J, Massidda O, Tonjum T, Henriques-normark B, Ron Ez
FEMS MICROBIOLOGY REVIEWS 2006;30(6):841-52

Group a streptococci from carriage and disease in Portugal: Evolution of antimicrobial resistance and T antigenic types during 2000-2002
Pires R, Rolo D, Gama-norton L, Morais A, Lito L, Salgado Mj, et al
MICROBIAL DRUG RESISTANCE-MECHANISMS EPIDEMIOLOGY AND DISEASE 2005;11(4):360-70

Microbiology - A pathogen attacks while keeping up defense
Normark S, Nilsson C, Normark Bh
SCIENCE 2005;307(5713):1211-2

Myeloid differentiation factor 88-dependent signalling controls bacterial growth during colonization and systemic pneumococcal disease in mice
Albiger B, Sandgren A, Katsuragi H, Meyer-hoffert U, Beiter K, Wartha F, et al
CELLULAR MICROBIOLOGY 2005;7(11):1603-15

Virulence in mice of pneumococcal clonal types with known invasive disease potential in humans
Sandgren A, Albiger B, Orihuela Cj, Tuomanen E, Normark S, Henriques-normark B
JOURNAL OF INFECTIOUS DISEASES 2005;192(5):791-800

Capsular expression in Streptococcus pneumoniae negatively affects spontaneous and antibiotic-induced lysis and contributes to antibiotic tolerance
Fernebro J, Andersson I, Sublett J, Morfeldt E, Novak R, Tuomanen E, et al
JOURNAL OF INFECTIOUS DISEASES 2004;189(2):328-38

Differences in potency of intravenous polyspecific immunoglobulin G against streptococcal and staphylococcal superantigens: Implications for therapy of toxic shock syndrome
Darenberg J, Soderquist B, Normark Bh, Norrby-teglund A
CLINICAL INFECTIOUS DISEASES 2004;38(6):836-42

Effect of clonal and serotype-specific properties on the invasive capacity of Streptococcus pneumoniae
Sandgren A, Sjostrom K, Olsson-liljequist Bo, Christensson B, Samuelsson A, Kronvall G, et al
JOURNAL OF INFECTIOUS DISEASES 2004;189(5):785-96

Staphylococcal protein A inflames the lungs
Normark Bh, Normark S, Norrby-teglund A
NATURE MEDICINE 2004;10(8):780-1

The impact of active intervention on the spread of penicillin-resistant streptococcus pneumoniae in Swedish day-care centres
Hogberg L, Normark Bh, Ringberg H, Stenqvist K, Fredlund H, Geli P, et al
SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES 2004;36(9):629-35

Viridans streptococcal septicaemia in neutropenic patients: role of proinflammatory cytokines
Ihendyane N, Sparrelid E, Wretlind B, Remberger M, Andersson J, Ljungman P, et al
BONE MARROW TRANSPLANTATION 2004;33(1):79-85

Capsular types and antibiotic susceptibility of invasive Streptococcus pneumoniae among children in Sweden
Hedlund J, Sorberg M, Normark Bh, Kronvall G
SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES 2003;35(8):452-8

Clonal analysis of Streptococcus pneumoniae nonsusceptible to penicillin at day-care centers with index cases, in a region with low incidence of resistance: Emergence of an invasive type 35B clone among carriers
Normark Bh, Christensson B, Sandgren A, Noreen B, Sylvan S, Burman Lg, et al
MICROBIAL DRUG RESISTANCE-MECHANISMS EPIDEMIOLOGY AND DISEASE 2003;9(4):337-44

Group A streptococcal infections in Sweden: A comparative study of invasive and noninvasive infections and analysis of dominant T28 emm28 isolates
Eriksson Bkg, Norgren M, Mcgregor K, Spratt Bg, Normark Bh
CLINICAL INFECTIOUS DISEASES 2003;37(9):1189-93

Innate immune responses caused by Streptococcus pneumoniae in TLR-knockout mice.
Katsuragi H, Albiger B, Sandgren A, Normark S, Normark Bh
JOURNAL OF DENTAL RESEARCH 2003;:B220-B220

Intracellular recognition of lipopolysaccharide by Toll-like receptor 4 in intestinal epithelial cells
Hornef Mw, Normark Bh, Vandewalle A, Normark S
JOURNAL OF EXPERIMENTAL MEDICINE 2003;198(8):1225-35

Persistent infection with Helicobacter pylori and the development of gastric cancer
Normark S, Nilsson C, Normark Bh, Hornef Mw
ADVANCES IN CANCER RESEARCH, VOL 90 2003;:63-89

RAPD-PCR and PFGE as tools in the investigation of an outbreak of beta-haemolytic Streptococcus group A in a Swedish hospital
Gonzalez-rey C, Belin Am, Jorbeck H, Norman M, Krovacek K, Henriques B, et al
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES 2003;26(1):25-35

Toxin-gene profile heterogeneity among endemic invasive European group A streptococcal isolates
Schmitz Fj, Beyer A, Charpentier E, Normark Bh, Schade M, Fluit Ac, et al
JOURNAL OF INFECTIOUS DISEASES 2003;188(10):1578-86

Antibiotic tolerance in pneumococci
Normark Bh, Normark S
CLINICAL MICROBIOLOGY AND INFECTION 2002;8(10):613-22

Evolution and spread of antibiotic resistance
Normark Bh, Normark S
JOURNAL OF INTERNAL MEDICINE 2002;252(2):91-106

Hosting for the cruel and the inconsequential
Normark Bh, Normark S
NATURE MEDICINE 2002;8(12):1349-50

Changes in serotype distribution may hamper efficacy of pneumococcal conjugate vaccines in children
Normark Bh, Ortqvist A, Kalin M, Olsson-liljequist B, Hedlund J, Svenson Sb, et al
SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES 2001;33(11):848-50

Clinical isolates of Streptococcus pneumoniae that exhibit tolerance of vancomycin
Normark Bh, Novak R, Ortqvist A, Kallenius G, Tuomanen E, Normark S
CLINICAL INFECTIOUS DISEASES 2001;32(4):552-8

Dynamics of penicillin-susceptible clones in invasive pneumococcal disease
Normark Bh, Kalin M, Ortqvist A, Akerlund T, Liljequist Bo, Hedlund J, et al
JOURNAL OF INFECTIOUS DISEASES 2001;184(7):861-9

How neutrophils recognize bacteria and move toward infection
Normark S, Normark Bh, Hornef M
NATURE MEDICINE 2001;7(11):1182-4

Epidemiology of pneumococcal infections in Swedish children
Eriksson M, Henriques B, Ekdahl K
ACTA PAEDIATRICA 2000;:35-9

Invasive group A streptococcal infections in Sweden in 1994 and 1995: Epidemiology and clinical spectrum
Svensson N, Oberg S, Henriques B, Holm S, Kallenius G, Romanus V, et al
SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES 2000;32(6):609-14

Molecular epidemiology of Streptococcus pneumoniae causing invasive disease in 5 countries
Henriques B, Kalin M, Ortqvist A, Liljequist Bo, Almela M, Marrie Tj, et al
JOURNAL OF INFECTIOUS DISEASES 2000;182(3):833-9

Prospective study of prognostic factors in community-acquired bacteremic pneumococcal disease in 5 countries
Kalin M, Ortqvist A, Almela M, Aufwerber E, Dwyer R, Henriques B, et al
JOURNAL OF INFECTIOUS DISEASES 2000;182(3):840-7

Emergence of vancomycin tolerance in Streptococcus pneumoniae
Novak R, Henriques B, Charpentier E, Normark S, Tuomanen E
NATURE 1999;399(6736):590-3

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