Andreas Lennartsson

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: LEUKEMIA. 2023;37(9):1830-1841

Perturbed epigenetic transcriptional regulation in AML with IDH mutations causes increased susceptibility to NK cells.

Palau A; Segerberg F; Lidschreiber M; Lidschreiber K; Naughton AJ; Needhamsen M; Jung LA; Jagodic M; Cramer P; Lehmann S; Carlsten M; Lennartsson A
Article: NUCLEIC ACIDS RESEARCH. 2023;51(D1):D564-D570

EpiFactors 2022: expansion and enhancement of a curated database of human epigenetic factors and complexes.

Marakulina D; Vorontsov IE; Kulakovskiy IV; Lennartsson A; Drabløs F; Medvedeva YA
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(19):11413

RUNX1/CEBPA Mutation in Acute Myeloid Leukemia Promotes Hypermethylation and Indicates for Demethylation Therapy.

Romanova EI; Zubritskiy AV; Lioznova AV; Ogunleye AJ; Golotin VA; Guts AA; Lennartsson A; Demidov ON; Medvedeva YA
Article: ACTA NEUROPSYCHIATRICA. 2022;34(2):86-92

Sirtuins and neuropeptide y downregulation in Flinders Sensitive Line rat model of depression.

Stiernborg M; Efstathopoulos P; Lennartsson A; Lavebratt C; Mathé AA
Article: BLOOD ADVANCES. 2021;5(4):1003-1016

Challenging conventional karyotyping by next-generation karyotyping in 281 intensively treated patients with AML.

Mareschal S; Palau A; Lindberg J; Ruminy P; Nilsson C; Bengtzén S; Engvall M; Eriksson A; Neddermeyer A; Marchand V; Jansson M; Björklund M; Jardin F; Rantalainen M; Lennartsson A; Cavelier L; Grönberg H; Lehmann S
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(4):1793

The Role of Non-Catalytic Domains of Hrp3 in Nucleosome Remodeling.

Dong W; Prasad P; Lennartsson A; Ekwall K
Article: BLOOD. 2020;136(3):339-352

AML displays increased CTCF occupancy associated with aberrant gene expression and transcription factor binding.

Mujahed H; Miliara S; Neddermeyer A; Bengtzén S; Nilsson C; Deneberg S; Cordeddu L; Ekwall K; Lennartsson A; Lehmann S
Article: EPIGENETICS. 2020;15(6-7):702-714

A regulatory role for CHD2 in myelopoiesis.

Shahin Varnoosfaderani F; Palau A; Dong W; Persson J; Durand-Dubief M; Svensson JP; Lennartsson A
Article: GENOME RESEARCH. 2020;30(7):1060-1072

Functional annotation of human long noncoding RNAs via molecular phenotyping.

Ramilowski JA; Yip CW; Agrawal S; Chang J-C; Ciani Y; Kulakovskiy IV; Mendez M; Ooi JLC; Ouyang JF; Parkinson N; Petri A; Roos L; Severin J; Yasuzawa K; Abugessaisa I; Akalin A; Antonov IV; Arner E; Bonetti A; Bono H; Borsari B; Brombacher F; Cameron CJF; Cannistraci CV; Cardenas R; Cardon M; Chang H; Dostie J; Ducoli L; Favorov A; Fort A; Garrido D; Gil N; Gimenez J; Guler R; Handoko L; Harshbarger J; Hasegawa A; Hasegawa Y; Hashimoto K; Hayatsu N; Heutink P; Hirose T; Imada EL; Itoh M; Kaczkowski B; Kanhere A; Kawabata E; Kawaji H; Kawashima T; Kelly ST; Kojima M; Kondo N; Koseki H; Kouno T; Kratz A; Kurowska-Stolarska M; Kwon ATJ; Leek J; Lennartsson A; Lizio M; López-Redondo F; Luginbühl J; Maeda S; Makeev VJ; Marchionni L; Medvedeva YA; Minoda A; Müller F; Muñoz-Aguirre M; Murata M; Nishiyori H; Nitta KR; Noguchi S; Noro Y; Nurtdinov R; Okazaki Y; Orlando V; Paquette D; Parr CJC; Rackham OJL; Rizzu P; Sánchez Martinez DF; Sandelin A; Sanjana P; Semple CAM; Shibayama Y; Sivaraman DM; Suzuki T; Szumowski SC; Tagami M; Taylor MS; Terao C; Thodberg M; Thongjuea S; Tripathi V; Ulitsky I; Verardo R; Vorontsov IE; Yamamoto C; Young RS; Baillie JK; Forrest ARR; Guigó R; Hoffman MM; Hon CC; Kasukawa T; Kauppinen S; Kere J; Lenhard B; Schneider C; Suzuki H; Yagi K; de Hoon MJL; Shin JW; Carninci P
Article: SCIENTIFIC REPORTS. 2020;10(1):6055

Abo1 is required for the H3K9me2 to H3K9me3 transition in heterochromatin.

Dong W; Oya E; Zahedi Y; Prasad P; Svensson JP; Lennartsson A; Ekwall K; Durand-Dubief M
Article: EXPERIMENTAL HEMATOLOGY. 2019;79:35-46.e1

Depletion of the transcriptional coactivators CREB-binding protein or EP300 downregulates CD20 in diffuse large B-cell lymphoma cells and impairs the cytotoxic effects of anti-CD20 antibodies.

Scialdone A; Khazaei S; Hasni MS; Lennartsson A; Gullberg U; Drott K
Article: ONCOTARGET. 2017;8(70):115002-115017

Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes.

Palau A; Garz A-K; Diesch J; Zwick A; Malinverni R; Valero V; Lappin K; Casquero R; Lennartsson A; Zuber J; Navarro T; Mills KI; Götze KS; Buschbeck M
Article: ONCOTARGET. 2017;8(50):87136-87150

The transcriptional coregulator NAB2 is a target gene for the Wilms' tumor gene 1 protein (WT1) in leukemic cells.

Nilsson HJ; Montano G; Ullmark T; Lennartsson A; Drott K; Järvstråt L; Nilsson B; Vidovic K; Gullberg U
Article: ELIFE. 2017;6:e29156

Major transcriptional changes observed in the Fulani, an ethnic group less susceptible to malaria.

Quin JE; Bujila I; Chérif M; Sanou GS; Qu Y; Vafa Homann M; Rolicka A; Sirima SB; O'Connell MA; Lennartsson A; Troye-Blomberg M; Nebie I; Östlund Farrants A-K
Article: SCIENTIFIC DATA. 2017;4:170112

FANTOM5 CAGE profiles of human and mouse samples.

Noguchi S; Arakawa T; Fukuda S; Furuno M; Hasegawa A; Hori F; Ishikawa-Kato S; Kaida K; Kaiho A; Kanamori-Katayama M; Kawashima T; Kojima M; Kubosaki A; Manabe R-I; Murata M; Nagao-Sato S; Nakazato K; Ninomiya N; Nishiyori-Sueki H; Noma S; Saijyo E; Saka A; Sakai M; Simon C; Suzuki N; Tagami M; Watanabe S; Yoshida S; Arner P; Axton RA; Babina M; Baillie JK; Barnett TC; Beckhouse AG; Blumenthal A; Bodega B; Bonetti A; Briggs J; Brombacher F; Carlisle AJ; Clevers HC; Davis CA; Detmar M; Dohi T; Edge ASB; Edinger M; Ehrlund A; Ekwall K; Endoh M; Enomoto H; Eslami A; Fagiolini M; Fairbairn L; Farach-Carson MC; Faulkner GJ; Ferrai C; Fisher ME; Forrester LM; Fujita R; Furusawa J-I; Geijtenbeek TB; Gingeras T; Goldowitz D; Guhl S; Guler R; Gustincich S; Ha TJ; Hamaguchi M; Hara M; Hasegawa Y; Herlyn M; Heutink P; Hitchens KJ; Hume DA; Ikawa T; Ishizu Y; Kai C; Kawamoto H; Kawamura YI; Kempfle JS; Kenna TJ; Kere J; Khachigian LM; Kitamura T; Klein S; Klinken SP; Knox AJ; Kojima S; Koseki H; Koyasu S; Lee W; Lennartsson A; Mackay-Sim A; Mejhert N; Mizuno Y; Morikawa H; Morimoto M; Moro K; Morris KJ; Motohashi H; Mummery CL; Nakachi Y; Nakahara F; Nakamura T; Nakamura Y; Nozaki T; Ogishima S; Ohkura N; Ohno H; Ohshima M; Okada-Hatakeyama M; Okazaki Y; Orlando V; Ovchinnikov DA; Passier R; Patrikakis M; Pombo A; Pradhan-Bhatt S; Qin X-Y; Rehli M; Rizzu P; Roy S; Sajantila A; Sakaguchi S; Sato H; Satoh H; Savvi S; Saxena A; Schmidl C; Schneider C; Schulze-Tanzil GG; Schwegmann A; Sheng G; Shin JW; Sugiyama D; Sugiyama T; Summers KM; Takahashi N; Takai J; Tanaka H; Tatsukawa H; Tomoiu A; Toyoda H; van de Wetering M; van den Berg LM; Verardo R; Vijayan D; Wells CA; Winteringham LN; Wolvetang E; Yamaguchi Y; Yamamoto M; Yanagi-Mizuochi C; Yoneda M; Yonekura Y; Zhang PG; Zucchelli S; Abugessaisa I; Arner E; Harshbarger J; Kondo A; Lassmann T; Lizio M; Sahin S; Sengstag T; Severin J; Shimoji H; Suzuki M; Suzuki H; Kawai J; Kondo N; Itoh M; Daub CO; Kasukawa T; Kawaji H; Carninci P; Forrest ARR; Hayashizaki Y
Article: ONCOTARGET. 2017;8(23):37409-37422

The HDAC inhibitor valproate induces a bivalent status of the CD20 promoter in CLL patients suggesting distinct epigenetic regulation of CD20 expression in CLL in vivo.

Scialdone A; Hasni MS; Damm JK; Lennartsson A; Gullberg U; Drott K
Article: ONCOTARGET. 2017;8(17):28812-28825

Comprehensive mapping of the effects of azacitidine on DNA methylation, repressive/permissive histone marks and gene expression in primary cells from patients with MDS and MDS-related disease.

Tobiasson M; Abdulkadir H; Lennartsson A; Katayama S; Marabita F; De Paepe A; Karimi M; Krjutskov K; Einarsdottir E; Grövdal M; Jansson M; Ben Azenkoud A; Corddedu L; Lehmann S; Ekwall K; Kere J; Hellström-Lindberg E; Ungerstedt J
Article: BLOOD. 2017;129(7):e13-e25

Cancer-specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia.

Qu Y; Siggens L; Cordeddu L; Gaidzik VI; Karlsson K; Bullinger L; Döhner K; Ekwall K; Lehmann S; Lennartsson A
Article: HAEMATOLOGICA. 2017;102(2):336-345

Distinct global binding patterns of the Wilms tumor gene 1 (WT1) -KTS and +KTS isoforms in leukemic cells.

Ullmark T; Järvstråt L; Sandén C; Montano G; Jernmark-Nilsson H; Lilljebjörn H; Lennartsson A; Fioretos T; Drott K; Vidovic K; Nilsson B; Gullberg U
Article: NUCLEIC ACIDS RESEARCH. 2017;45(D1):D737-D743

Update of the FANTOM web resource: high resolution transcriptome of diverse cell types in mammals.

Lizio M; Harshbarger J; Abugessaisa I; Noguchi S; Kondo A; Severin J; Mungall C; Arenillas D; Mathelier A; Medvedeva YA; Lennartsson A; Drabløs F; Ramilowski JA; Rackham O; Gough J; Andersson R; Sandelin A; Ienasescu H; Ono H; Bono H; Hayashizaki Y; Carninci P; Forrest ARR; Kasukawa T; Kawaji H
Article: ONCOTARGET. 2016;7(16):22103-22115

Mutations in histone modulators are associated with prolonged survival during azacitidine therapy.

Tobiasson M; McLornan DP; Karimi M; Dimitriou M; Jansson M; Ben Azenkoud A; Jädersten M; Lindberg G; Abdulkadir H; Kulasekararaj A; Ungerstedt J; Lennartsson A; Ekwall K; Mufti GJ; Hellström-Lindberg E
Article: EXPERIMENTAL HEMATOLOGY. 2015;43(8):609-624

Epigenetic aberrations in acute myeloid leukemia: Early key events during leukemogenesis.

Eriksson A; Lennartsson A; Lehmann S
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2015;97(5):985-995

Technical Advance: Transcription factor, promoter, and enhancer utilization in human myeloid cells.

Joshi A; Pooley C; Freeman TC; Lennartsson A; Babina M; Schmidl C; Geijtenbeek T; FANTOM Consortium; Michoel T; Severin J; Itoh M; Lassmann T; Kawaji H; Hayashizaki Y; Carninci P; Forrest ARR; Rehli M; Hume DA
Article: SCIENCE. 2015;347(6225):1010-1014

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.

Arner E; Daub CO; Vitting-Seerup K; Andersson R; Lilje B; Drabløs F; Lennartsson A; Rönnerblad M; Hrydziuszko O; Vitezic M; Freeman TC; Alhendi AMN; Arner P; Axton R; Baillie JK; Beckhouse A; Bodega B; Briggs J; Brombacher F; Davis M; Detmar M; Ehrlund A; Endoh M; Eslami A; Fagiolini M; Fairbairn L; Faulkner GJ; Ferrai C; Fisher ME; Forrester L; Goldowitz D; Guler R; Ha T; Hara M; Herlyn M; Ikawa T; Kai C; Kawamoto H; Khachigian LM; Klinken SP; Kojima S; Koseki H; Klein S; Mejhert N; Miyaguchi K; Mizuno Y; Morimoto M; Morris KJ; Mummery C; Nakachi Y; Ogishima S; Okada-Hatakeyama M; Okazaki Y; Orlando V; Ovchinnikov D; Passier R; Patrikakis M; Pombo A; Qin X-Y; Roy S; Sato H; Savvi S; Saxena A; Schwegmann A; Sugiyama D; Swoboda R; Tanaka H; Tomoiu A; Winteringham LN; Wolvetang E; Yanagi-Mizuochi C; Yoneda M; Zabierowski S; Zhang P; Abugessaisa I; Bertin N; Diehl AD; Fukuda S; Furuno M; Harshbarger J; Hasegawa A; Hori F; Ishikawa-Kato S; Ishizu Y; Itoh M; Kawashima T; Kojima M; Kondo N; Lizio M; Meehan TF; Mungall CJ; Murata M; Nishiyori-Sueki H; Sahin S; Nagao-Sato S; Severin J; de Hoon MJL; Kawai J; Kasukawa T; Lassmann T; Suzuki H; Kawaji H; Summers KM; Wells C; FANTOM Consortium; Hume DA; Forrest ARR; Sandelin A; Carninci P; Hayashizaki Y
Article: EPIGENETICS & CHROMATIN. 2015;8(1):4

Transcription-coupled recruitment of human CHD1 and CHD2 influences chromatin accessibility and histone H3 and H3.3 occupancy at active chromatin regions.

Siggens L; Cordeddu L; Rönnerblad M; Lennartsson A; Ekwall K
Article: DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION. 2015;2015:bav067

EpiFactors: a comprehensive database of human epigenetic factors and complexes.

Medvedeva YA; Lennartsson A; Ehsani R; Kulakovskiy IV; Vorontsov IE; Panahandeh P; Khimulya G; Kasukawa T; FANTOM Consortium; Drabløs F
Article: EPIGENETICS & CHROMATIN. 2015;8:55

Remodeling of retrotransposon elements during epigenetic induction of adult visual cortical plasticity by HDAC inhibitors.

Lennartsson A; Arner E; Fagiolini M; Saxena A; Andersson R; Takahashi H; Noro Y; Sng J; Sandelin A; Hensch TK; Carninci P
Article: MOLECULAR CANCER. 2014;13:215

The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation.

Sandén C; Järvstråt L; Lennartsson A; Brattås PL; Nilsson B; Gullberg U
Article: EPIGENETICS. 2014;9(8):1108-1119

Differential methylation in CN-AML preferentially targets non-CGI regions and is dictated by DNMT3A mutational status and associated with predominant hypomethylation of HOX genes.

Qu Y; Lennartsson A; Gaidzik VI; Deneberg S; Karimi M; Bengtzén S; Höglund M; Bullinger L; Döhner K; Lehmann S
Article: EPIGENETICS. 2014;9(6):910-917

microRNA-34b/c on chromosome 11q23 is aberrantly methylated in chronic lymphocytic leukemia.

Deneberg S; Kanduri M; Ali D; Bengtzen S; Karimi M; Qu Y; Kimby E; Mansouri L; Rosenquist R; Lennartsson A; Lehmann S
Article: BLOOD. 2014;123(17):e79-e89

Analysis of the DNA methylome and transcriptome in granulopoiesis reveals timed changes and dynamic enhancer methylation.

Rönnerblad M; Andersson R; Olofsson T; Douagi I; Karimi M; Lehmann S; Hoof I; de Hoon M; Itoh M; Nagao-Sato S; Kawaji H; Lassmann T; Carninci P; Hayashizaki Y; Forrest ARR; Sandelin A; Ekwall K; Arner E; Lennartsson A; FANTOM consortium
Article: BLOOD. 2014;123(17):e46-e57

High-throughput transcription profiling identifies putative epigenetic regulators of hematopoiesis.

Prasad P; Rönnerblad M; Arner E; Itoh M; Kawaji H; Lassmann T; Daub CO; Forrest ARR; Lennartsson A; Ekwall K; FANTOM consortium
Article: NATURE. 2014;507(7493):462-470

A promoter-level mammalian expression atlas.

FANTOM Consortium and the RIKEN PMI and CLST (DGT); Forrest ARR; Kawaji H; Rehli M; Baillie JK; de Hoon MJL; Haberle V; Lassmann T; Kulakovskiy IV; Lizio M; Itoh M; Andersson R; Mungall CJ; Meehan TF; Schmeier S; Bertin N; Jørgensen M; Dimont E; Arner E; Schmidl C; Schaefer U; Medvedeva YA; Plessy C; Vitezic M; Severin J; Semple CA; Ishizu Y; Young RS; Francescatto M; Alam I; Albanese D; Altschuler GM; Arakawa T; Archer JAC; Arner P; Babina M; Rennie S; Balwierz PJ; Beckhouse AG; Pradhan-Bhatt S; Blake JA; Blumenthal A; Bodega B; Bonetti A; Briggs J; Brombacher F; Burroughs AM; Califano A; Cannistraci CV; Carbajo D; Chen Y; Chierici M; Ciani Y; Clevers HC; Dalla E; Davis CA; Detmar M; Diehl AD; Dohi T; Drabløs F; Edge ASB; Edinger M; Ekwall K; Endoh M; Enomoto H; Fagiolini M; Fairbairn L; Fang H; Farach-Carson MC; Faulkner GJ; Favorov AV; Fisher ME; Frith MC; Fujita R; Fukuda S; Furlanello C; Furino M; Furusawa J-I; Geijtenbeek TB; Gibson AP; Gingeras T; Goldowitz D; Gough J; Guhl S; Guler R; Gustincich S; Ha TJ; Hamaguchi M; Hara M; Harbers M; Harshbarger J; Hasegawa A; Hasegawa Y; Hashimoto T; Herlyn M; Hitchens KJ; Ho Sui SJ; Hofmann OM; Hoof I; Hori F; Huminiecki L; Iida K; Ikawa T; Jankovic BR; Jia H; Joshi A; Jurman G; Kaczkowski B; Kai C; Kaida K; Kaiho A; Kajiyama K; Kanamori-Katayama M; Kasianov AS; Kasukawa T; Katayama S; Kato S; Kawaguchi S; Kawamoto H; Kawamura YI; Kawashima T; Kempfle JS; Kenna TJ; Kere J; Khachigian LM; Kitamura T; Klinken SP; Knox AJ; Kojima M; Kojima S; Kondo N; Koseki H; Koyasu S; Krampitz S; Kubosaki A; Kwon AT; Laros JFJ; Lee W; Lennartsson A; Li K; Lilje B; Lipovich L; Mackay-Sim A; Manabe R-I; Mar JC; Marchand B; Mathelier A; Mejhert N; Meynert A; Mizuno Y; de Lima Morais DA; Morikawa H; Morimoto M; Moro K; Motakis E; Motohashi H; Mummery CL; Murata M; Nagao-Sato S; Nakachi Y; Nakahara F; Nakamura T; Nakamura Y; Nakazato K; van Nimwegen E; Ninomiya N; Nishiyori H; Noma S; Noma S; Noazaki T; Ogishima S; Ohkura N; Ohimiya H; Ohno H; Ohshima M; Okada-Hatakeyama M; Okazaki Y; Orlando V; Ovchinnikov DA; Pain A; Passier R; Patrikakis M; Persson H; Piazza S; Prendergast JGD; Rackham OJL; Ramilowski JA; Rashid M; Ravasi T; Rizzu P; Roncador M; Roy S; Rye MB; Saijyo E; Sajantila A; Saka A; Sakaguchi S; Sakai M; Sato H; Savvi S; Saxena A; Schneider C; Schultes EA; Schulze-Tanzil GG; Schwegmann A; Sengstag T; Sheng G; Shimoji H; Shimoni Y; Shin JW; Simon C; Sugiyama D; Sugiyama T; Suzuki M; Suzuki N; Swoboda RK; 't Hoen PAC; Tagami M; Takahashi N; Takai J; Tanaka H; Tatsukawa H; Tatum Z; Thompson M; Toyodo H; Toyoda T; Valen E; van de Wetering M; van den Berg LM; Verado R; Vijayan D; Vorontsov IE; Wasserman WW; Watanabe S; Wells CA; Winteringham LN; Wolvetang E; Wood EJ; Yamaguchi Y; Yamamoto M; Yoneda M; Yonekura Y; Yoshida S; Zabierowski SE; Zhang PG; Zhao X; Zucchelli S; Summers KM; Suzuki H; Daub CO; Kawai J; Heutink P; Hide W; Freeman TC; Lenhard B; Bajic VB; Taylor MS; Makeev VJ; Sandelin A; Hume DA; Carninci P; Hayashizaki Y
Article: NATURE. 2014;507(7493):455-461

An atlas of active enhancers across human cell types and tissues.

Andersson R; Gebhard C; Miguel-Escalada I; Hoof I; Bornholdt J; Boyd M; Chen Y; Zhao X; Schmidl C; Suzuki T; Ntini E; Arner E; Valen E; Li K; Schwarzfischer L; Glatz D; Raithel J; Lilje B; Rapin N; Bagger FO; Jørgensen M; Andersen PR; Bertin N; Rackham O; Burroughs AM; Baillie JK; Ishizu Y; Shimizu Y; Furuhata E; Maeda S; Negishi Y; Mungall CJ; Meehan TF; Lassmann T; Itoh M; Kawaji H; Kondo N; Kawai J; Lennartsson A; Daub CO; Heutink P; Hume DA; Jensen TH; Suzuki H; Hayashizaki Y; Müller F; Forrest ARR; Carninci P; Rehli M; Sandelin A
Article: LEUKEMIA RESEARCH. 2013;37(10):1341-1349

Leukemia associated mutant Wilms' tumor gene 1 protein promotes expansion of human hematopoietic progenitor cells.

Vidovic K; Ullmark T; Rosberg B; Lennartsson A; Olofsson T; Nilsson B; Gullberg U
Article: BMC CANCER. 2013;13:440

Forced expression of the DEK-NUP214 fusion protein promotes proliferation dependent on upregulation of mTOR.

Sandén C; Ageberg M; Petersson J; Lennartsson A; Gullberg U
Article: TRANSLATIONAL PSYCHIATRY. 2013;3(5):e255

Allele-specific programming of Npy and epigenetic effects of physical activity in a genetic model of depression.

Melas PA; Lennartsson A; Vakifahmetoglu-Norberg H; Wei Y; Åberg E; Werme M; Rogdaki M; Mannervik M; Wegener G; Brené S; Mathé AA; Lavebratt C
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2012;15(5):669-679

Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression.

Melas PA; Rogdaki M; Lennartsson A; Björk K; Qi H; Witasp A; Werme M; Wegener G; Mathé AA; Svenningsson P; Lavebratt C
Article: BLOOD. 2011;118(20):5573-5582

Prognostic DNA methylation patterns in cytogenetically normal acute myeloid leukemia are predefined by stem cell chromatin marks.

Deneberg S; Guardiola P; Lennartsson A; Qu Y; Gaidzik V; Blanchet O; Karimi M; Bengtzén S; Nahi H; Uggla B; Tidefelt U; Höglund M; Paul C; Ekwall K; Döhner K; Lehmann S
Article: LEUKEMIA. 2010;24(5):992-1000

Wilms' tumor gene 1 protein represses the expression of the tumor suppressor interferon regulatory factor 8 in human hematopoietic progenitors and in leukemic cells.

Vidovic K; Svensson E; Nilsson B; Thuresson B; Olofsson T; Lennartsson A; Gullberg U
Article: NATURE GENETICS. 2009;41(5):553-562

The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line.

FANTOM Consortium; Suzuki H; Forrest ARR; van Nimwegen E; Daub CO; Balwierz PJ; Irvine KM; Lassmann T; Ravasi T; Hasegawa Y; de Hoon MJL; Katayama S; Schroder K; Carninci P; Tomaru Y; Kanamori-Katayama M; Kubosaki A; Akalin A; Ando Y; Arner E; Asada M; Asahara H; Bailey T; Bajic VB; Bauer D; Beckhouse AG; Bertin N; Björkegren J; Brombacher F; Bulger E; Chalk AM; Chiba J; Cloonan N; Dawe A; Dostie J; Engström PG; Essack M; Faulkner GJ; Fink JL; Fredman D; Fujimori K; Furuno M; Gojobori T; Gough J; Grimmond SM; Gustafsson M; Hashimoto M; Hashimoto T; Hatakeyama M; Heinzel S; Hide W; Hofmann O; Hörnquist M; Huminiecki L; Ikeo K; Imamoto N; Inoue S; Inoue Y; Ishihara R; Iwayanagi T; Jacobsen A; Kaur M; Kawaji H; Kerr MC; Kimura R; Kimura S; Kimura Y; Kitano H; Koga H; Kojima T; Kondo S; Konno T; Krogh A; Kruger A; Kumar A; Lenhard B; Lennartsson A; Lindow M; Lizio M; Macpherson C; Maeda N; Maher CA; Maqungo M; Mar J; Matigian NA; Matsuda H; Mattick JS; Meier S; Miyamoto S; Miyamoto-Sato E; Nakabayashi K; Nakachi Y; Nakano M; Nygaard S; Okayama T; Okazaki Y; Okuda-Yabukami H; Orlando V; Otomo J; Pachkov M; Petrovsky N; Plessy C; Quackenbush J; Radovanovic A; Rehli M; Saito R; Sandelin A; Schmeier S; Schönbach C; Schwartz AS; Semple CA; Sera M; Severin J; Shirahige K; Simons C; St Laurent G; Suzuki M; Suzuki T; Sweet MJ; Taft RJ; Takeda S; Takenaka Y; Tan K; Taylor MS; Teasdale RD; Tegnér J; Teichmann S; Valen E; Wahlestedt C; Waki K; Waterhouse A; Wells CA; Winther O; Wu L; Yamaguchi K; Yanagawa H; Yasuda J; Zavolan M; Hume DA; Riken Omics Science Center; Arakawa T; Fukuda S; Imamura K; Kai C; Kaiho A; Kawashima T; Kawazu C; Kitazume Y; Kojima M; Miura H; Murakami K; Murata M; Ninomiya N; Nishiyori H; Noma S; Ogawa C; Sano T; Simon C; Tagami M; Takahashi Y; Kawai J; Hayashizaki Y
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2006;80(1):196-203

All-trans retinoic acid-induced expression of bactericidal/permeability-increasing protein (BPI) in human myeloid cells correlates to binding of C/EBPbeta and C/EBPepsilon to the BPI promoter.

Lennartsson A; Vidovic K; Pass MB; Cowland JB; Gullberg U
Article: AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY. 2006;290(3):G557-G567

Functional and biochemical characterization of epithelial bactericidal/permeability-increasing protein.

Canny G; Cario E; Lennartsson A; Gullberg U; Brennan C; Levy O; Colgan SP
Article: GENE. 2005;356:193-202

The proximal promoter of the human cathepsin G gene conferring myeloid-specific expression includes C/EBP, c-myb and PU.1 binding sites.

Lennartsson A; Garwicz D; Lindmark A; Gullberg U
Article: HAEMATOLOGICA. 2005;90(1):38-44

Biosynthetic profiles of neutrophil serine proteases in a human bone marrow-derived cellular myeloid differentiation model.

Garwicz D; Lennartsson A; Jacobsen SEW; Gullberg U; Lindmark A
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2004;77(3):369-377

A murine antibacterial ortholog to human bactericidal/permeability-increasing protein (BPI) is expressed in testis, epididymis, and bone marrow.

Lennartsson A; Pieters K; Vidovic K; Gullberg U
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2003;311(4):853-863

AML-1, PU.1, and Sp3 regulate expression of human bactericidal/permeability-increasing protein.

Lennartsson A; Pieters K; Ullmark T; Vidovic K; Gullberg U
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Letter: LEUKEMIA. 2024;38(3):663-666

The exon-junction complex helicase eIF4A3 holds therapeutic potential in acute myeloid leukemia.

Miliara S; Cozzi E; Zhong X; Chan I; Ekwall K; Lehmann S; Lennartsson A; Bartek J; Kanellis DC
Review: EPIGENOMES. 2021;5(4):22

One Omics Approach Does Not Rule Them All: The Metabolome and the Epigenome Join Forces in Haematological Malignancies.

Kalushkova A; Nylund P; Párraga AA; Lennartsson A; Jernberg-Wiklund H
Editorial comment: GENOME BIOLOGY. 2016;17:18

External signals shape the epigenome.

Lennartsson A
Review: BIOMED RESEARCH INTERNATIONAL. 2015;2015:347571-17

The roles of SNF2/SWI2 nucleosome remodeling enzymes in blood cell differentiation and leukemia.

Prasad P; Lennartsson A; Ekwall K
Editorial comment: ACTA NEUROPSYCHIATRICA. 2012;24(5):253-254

Epigenetic alterations related to early life stressful events.

Lennartsson A
Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2009;1790(9):863-868

Histone modification patterns and epigenetic codes.

Lennartsson A; Ekwall K

Anställningar

Senior Forskare, Medicin, Huddinge, Karolinska Institutet, 2024-
Senior Forskare, Biovetenskaper och näringslära, Karolinska Institutet, 2024-2024
Senior Forskare, Biovetenskaper och näringslära, Karolinska Institutet, 2022-2024

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Docent, Experimentell hematologi, Karolinska Institutet, 2016

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