Publikationer - KaSP

Utvalda publikationer för Karolinska Schizophrenia project (KaSP).

Cerebrospinal fluid concentration of complement component 4A is increased in first episode schizophrenia.
Gracias J, Orhan F, Hörbeck E, Holmén-Larsson J, Khanlarkani N, Malwade S, Goparaju SK, Schwieler L, Demirel İŞ, Fu T, Fatourus-Bergman H, Pelanis A, Goold CP, Goulding A et al.
Nat Commun 2022 Nov;13(1):6427

Facial affect recognition in first-episode psychosis is impaired but not associated with psychotic symptoms.
Larsson C, Lee M, Lundgren T, Erhardt S, Sellgren CM, Cervenka S, Borg J, Bölte S, Fatouros-Bergman H
Heliyon 2022 Sep;8(9):e10424

Identification of cerebrospinal fluid and serum metabolomic biomarkers in first episode psychosis patients.
Shang P, Ho AM, Tufvesson-Alm M, Lindberg DR, Grant CW, Orhan F, Eren F, Bhat M, Engberg G, Schwieler L, Fatouros-Bergman H, Imbeault S, Iverson RM, Dasari S, Piehl F, Cervenka S, Sellgren CM, Erhardt S, Choi DS
Transl Psychiatry 2022 Jun;12(1):229

Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia.
Mätlik K, Garton DR, Montaño-Rodríguez AR, Olfat S, Eren F, Casserly L, Damdimopoulos A, Panhelainen A, Porokuokka LL, Kopra JJ, Turconi G, Schweizer N, Bereczki E, Piehl F, Engberg G, Cervenka S, Piepponen TP, Zhang FP, Sipilä P, Jakobsson J, Sellgren CM, Erhardt S, Andressoo JO
Mol Psychiatry 2022 Aug;27(8):3247-3261

Thalamic dopamine D2-receptor availability in schizophrenia: a study on antipsychotic-naive patients with first-episode psychosis and a meta-analysis.
Plavén-Sigray P, Ikonen Victorsson P, Santillo A, Matheson GJ, Lee M, Collste K, Fatouros-Bergman H, Sellgren CM, Erhardt S, Agartz I, Halldin C, Farde L, Cervenka S
Mol Psychiatry 2022 Feb;27(2):1233-1240

Screening for pathogenic neuronal autoantibodies in serum and CSF of patients with first-episode psychosis.
Theorell J, Ramberger M, Harrison R, Mgbachi V, Jacobson L, Waters P, Erhardt S, Sellgren CM, Cervenka S, Piehl F, Irani SR
Transl Psychiatry 2021 Nov;11(1):566

No association between cortical dopamine D2 receptor availability and cognition in antipsychotic-naive first-episode psychosis.
Lee M, Fatouros-Bergman H, Plavén-Sigray P, Ikonen Victorsson P, Sellgren CM, Erhardt S, Flyckt L, Farde L, Cervenka S
NPJ Schizophr 2021 Sep;7(1):46

Plasma bilirubin levels are reduced in first-episode psychosis patients and associates to working memory and duration of untreated psychosis.
Becklén M, Orhan F, Piehl F, Cervenka S, Sellgren CM, Flyckt L, Erhardt S, Fatouros-Bergman H
Sci Rep 2021 Apr;11(1):7527

Disrupted sensorimotor gating in first-episode psychosis patients is not affected by short-term antipsychotic treatment.
Hedberg M, Imbeault S, , Erhardt S, Schwieler L
Schizophr Res 2021 Feb;228():118-123

Brain Age Prediction Reveals Aberrant Brain White Matter in Schizophrenia and Bipolar Disorder: A Multisample Diffusion Tensor Imaging Study.
Tønnesen S, Kaufmann T, de Lange AG, Richard G, Doan NT, Alnæs D, van der Meer D, Rokicki J, Moberget T, Maximov II, Agartz I, Aminoff SR, Beck D, Barch DM, Beresniewicz J et al.
Biol Psychiatry Cogn Neurosci Neuroimaging 2020 Dec;5(12):1095-1103

Reproducibility in the absence of selective reporting: An illustration from large-scale brain asymmetry research.
Kong XZ, , Francks C
Hum Brain Mapp 2022 Jan;43(1):244-254

The genetic architecture of human brainstem structures and their involvement in common brain disorders.
Elvsåshagen T, Bahrami S, van der Meer D, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Beyer MK, Blasi G, Borgwardt S, Boye B, Buitelaar J, Bøen E, Celius EG et al.
Nat Commun 2020 Aug;11(1):4016

CSF levels of synaptosomal-associated protein 25 and synaptotagmin-1 in first-episode psychosis subjects.
Xu C, Sellgren CM, Fatouros-Bergman H, Piehl F, Blennow K, Zetterberg H, Brinkmalm A, Santillo AF, Lundgren S, Cervenka S, Engberg G, Erhardt S,
IBRO Rep 2020 Jun;8():136-142

Synthesis and Preclinical Evaluation of 6-[18F]Fluorine-α-methyl-l-tryptophan, a Novel PET Tracer for Measuring Tryptophan Uptake.
Krasikova R, Kondrashov M, Avagliano C, Petukhov M, Vazquez-Romero A, Revunov E, Johnström P, Tari L, Tóth M, Häggkvist J, Erhardt S, Cervenka S, Schou M
ACS Chem Neurosci 2020 Jun;11(12):1756-1761

Common brain disorders are associated with heritable patterns of apparent aging of the brain.
Kaufmann T, van der Meer D, Doan NT, Schwarz E, Lund MJ, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Bettella F, Beyer MK, Bøen E, Borgwardt S, Brandt CL, Buitelaar J et al.
Nat Neurosci 2019 Oct;22(10):1617-1623

Neurogranin as a potential synaptic marker in the cerebrospinal fluid of patients with a first episode psychosis.
Santillo AF, Lundgren S, Xu C, Orhan F, Fatouros-Bergman H, Blennow K, Zetterberg H, Portelius E, , Cervenka S, Jönsson EG, Erhardt S, Engberg G
Schizophr Res 2019 Jun;208():490-492

Increased peripheral levels of TARC/CCL17 in first episode psychosis patients.
Malmqvist A, Schwieler L, Orhan F, Fatouros-Bergman H, Bauer M, Flyckt L, Cervenka S, Engberg G, Piehl F, , Erhardt S
Schizophr Res 2019 Aug;210():221-227

Reply to: New Meta- and Mega-analyses of Magnetic Resonance Imaging Findings in Schizophrenia: Do They Really Increase Our Knowledge About the Nature of the Disease Process?
van Erp TGM, Walton E, Hibar DP, Schmaal L, Jiang W, Glahn DC, Pearlson GD, Yao N, Fukunaga M, Hashimoto R, Okada N, Yamamori H, Clark VP, Mueller BA, de Zwarte SMC, Ophoff RA et al.
Biol Psychiatry 2019 Apr;85(7):e35-e39

Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium.
van Erp TGM, Walton E, Hibar DP, Schmaal L, Jiang W, Glahn DC, et al
Biol. Psychiatry 2018 11;84(9):644-654

PET studies of the glial cell marker TSPO in psychosis patients - a meta-analysis using individual participant data.
Plavén-Sigray P, Matheson GJ, Collste K, Ashok AH, Coughlin JM, Howes O, Mizrahi R, Pomper MG, Rusjan P, Veronese M, Wang Y, Cervenka S
Biological Psychiatry 2018 02; 1171

Increased number of monocytes and plasma levels of MCP-1 and YKL-40 in first-episode psychosis.
Orhan F, Schwieler L, Fatouros-Bergman H, Malmqvist A, Cervenka S, Collste K, et al
Acta Psychiatr Scand 2018 11;138(5):432-440

Cerebrospinal fluid levels of sphingolipids associate with disease severity in first episode psychosis patients.
Checa A, Malmqvist A, Flyckt L, Schwieler L, Samuelsson M, Skogh E, et al
Schizophr. Res. 2018 09;199():438-441

First-episode psychosis patients display increased plasma IL-18 that correlates with cognitive dysfunction.
Orhan F, Fatouros-Bergman H, Schwieler L, Cervenka S, Flyckt L, Sellgren CM, et al
Schizophr. Res. 2018 05;195():406-408

Positive symptoms associate with cortical thinning in the superior temporal gyrus via the ENIGMA Schizophrenia consortium.
Walton E, Hibar DP, van Erp TG, Potkin SG, Roiz-Santiañez R, Crespo-Facorro B, et al
Acta Psychiatr Scand 2017 May;135(5):439-447

CSF GABA is reduced in first-episode psychosis and associates to symptom severity.
Orhan F, Fatouros-Bergman H, Goiny M, Malmqvist A, Piehl F, , et al
Mol. Psychiatry 2018 05;23(5):1244-1250

Lower levels of the glial cell marker TSPO in drug-naive first-episode psychosis patients as measured using PET and [11C]PBR28.
Collste K, Plavén-Sigray P, Fatouros-Bergman H, Victorsson P, Schain M, Forsberg A, et al
Mol. Psychiatry 2017 06;22(6):850-856

Tryptophan Metabolism Along the Kynurenine Pathway Downstream of Toll-like Receptor Stimulation in Peripheral Monocytes.
Orhan F, Bhat M, Sandberg K, Ståhl S, Piehl F, , et al
Scand. J. Immunol. 2016 Nov;84(5):262-271

Prefrontal cortical thinning links to negative symptoms in schizophrenia via the ENIGMA consortium.
Walton E, Hibar DP, van Erp TGM, Potkin SG, Roiz-Santiañez R, Crespo-Facorro B, et al
Psychol Med 2018 Jan;48(1):82-94

Linda Nilsson