Montage of journal covers: NEJM, Cell Stem Cell, BMJ, Nature and Science.

Top publications from Karolinska Institutet

Researchers at Karolinska Institutet publish over 7,000 articles in scientific journals each year. Listed here are current articles to which our researchers have contributed and that have been published in selected top-ranked journals and registered in the Medline and Web of Science databases. New articles are automatically fed onto this page approximately every other week. It is not possible to update the list manually.

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KI in the 2024 highly cited list (@Clarivate)

Latest top publications

Quantitative trait loci mapping of circulating metabolites in cerebrospinal fluid to uncover biological mechanisms involved in brain-related phenotypes
Reus LM, Boltz T, Francia M, Bot M, Ramesh N, Koromina M, Pijnenburg YAL, den Braber A, van der Flier WM, Visser PJ, van der Lee SJ, Tijms BM, Teunissen CE, Loohuis LO, Ophoff RAShow more
Molecular psychiatry
2025 Aug
KI-anknytning: Låg
Article
Harnessing omics data for drug discovery and development in ovarian aging
Zhang FY, Zhu M, Chen Y, Wang GQ, Yang HY, Lu XM, Li Y, Chang HM, Wu Y, Ma YL, Yuan S, Zhu WC, Dong X, Zhao Y, Yu Y, Wang J, Mu LSShow more
Human reproduction update
2025 May 01
KI-anknytning: Låg
Review
Prevalence and clinical relevance of viraemia in viral respiratory tract infections: a systematic review
Hagman K, Postigo T, Diez-Castro D, Ursing J, Bermejo-Martin JF, de la Fuente A, Tedim APShow more
The Lancet. Microbe
2025 Feb
KI-anknytning: Medel
Review
Early-Life Factors Associated With Adult-Onset Type 1 Diabetes: A Swedish Nationwide Cohort and Family-Based Study
Amadou C, Wei YX, Feychting M, Carlsson SShow more
Diabetes care
2024 Oct 01
KI-anknytning: Hög
Article
Risk of invasive meningococcal disease in people with sickle cell disease: A systematic review
Isitt C, Campbell H, Cosgrove CA, Ramsay ME, Heath PT, Borrow R, Ladhani SNShow more
The Journal of infection
2025 Mar
KI-anknytning: Hög
Review
Zanubrutinib Versus Bendamustine and Rituximab in Patients With Treatment-Naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: Median 5-Year Follow-Up of SEQUOIA
Shadman M, Munir T, Robak T, Brown JR, Kahl BS, Ghia P, Giannopoulos K, Simkovic M, Osterborg A, Laurenti L, Walker PA, Opat SS, Ciepluch H, Greil R, Hanna M, Tani M, Trneny M, Brander D, Flinn IW, Grosicki S, Verner E, Tedeschi A, de Guibert S, Tumyan G, Laribi K, Garcia-Marco JA, Li JY, Tian T, Liu Y, Korolkiewicz R, Szeto A, Tam CS, Jurczak WShow more
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
2025 Mar
KI-anknytning: Låg
Article
Vascular endothelial growth factor B-mediated fatty acid flux in the adipose-kidney axis contributes to lipotoxicity in diabetic kidney disease
Folestad E, Mehlem A, Ning FC, Oosterveld T, Palombo I, Singh J, Olauson H, Witasp A, Thorell A, Stenvinkel P, Ebefors K, Nystrom J, Eriksson U, Falkevall AShow more
Kidney international
2025 Mar
KI-anknytning: Hög
Article
Health benefits of leisure-time physical activity by socioeconomic status, lifestyle risk, and mental health: a multicohort study
Nyberg ST, Frank P, Pentti J, Alfredsson L, Ervasti J, Goldberg M, Knutsson A, Koskinen A, Lallukka T, Nordin M, Rahkonen O, Strandberg T, Suominen S, Vaananen A, Vahtera J, Virtanen M, Westerlund H, Zins M, Stenholm S, Sabia S, Singh-Manoux A, Hamer M, Kivimaki MShow more
The Lancet. Public health
2025 Feb
KI-anknytning: Låg
Article
TIGIT expression on natural killer cell subsets is an early indicator of alleviating liver inflammation following bulevirtide treatment in chronic hepatitis D
Chen PC, Deterding K, Engelskircher SA, Port K, Sandmann L, Chakkadath A, Ristic T, Wu QY, Bremer B, Kraft ARM, Cornberg M, Heim A, Kefalakes H, Bjorkstrom NK, Woller N, Wedemeyer HShow more
Hepatology (Baltimore, Md.)
2025 Jan 23
KI-anknytning: Låg
Article
Sex dimorphism in kidney health and disease: mechanistic insights and clinical implication
Steiger S, Li L, Bruchfeld A, Stevens KI, Moran SM, Floege J, Caravaca-Fontan F, Mirioglu S, Teng OYK, Frangou E, Kronbichler A, European Renal Assoc ERAImmunonephrology Working Grp IWGShow more
Kidney international
2025 Jan
KI-anknytning: Låg
Review
Durability of immunogenicity at 5 years after a single dose of human papillomavirus vaccine compared with two doses in Tanzanian girls aged 9-14 years: results of the long-term extension of the DoRIS randomised trial
Watson-Jones D, Changalucha J, Maxwell C, Whitworth H, Mutani P, Kemp TJ, Kamala B, Indangasi J, Constantine G, Hashim R, Mwanzalima D, Wiggins R, Mmbando D, Connor N, Pavon MA, Lowe B, Kapiga S, Mayaud P, de Sanjose S, Dillner J, Hayes RJ, Lacey CJ, Pinto L, Baisley KShow more
The Lancet. Global health
2025 02
KI-anknytning: Låg
Article
International Myeloma Working Group immunotherapy committee consensus guidelines and recommendations for optimal use of T-cell-engaging bispecific antibodies in multiple myeloma
Rodriguez-Otero P, Usmani S, Cohen AD, van de Donk NWCJ, Leleu X, Perez-Larraya JG, Manier S, Nooka AK, Mateos MV, Einsele H, Minnema M, Cavo M, Derman BA, Puig N, Gay F, Ho PJ, Chng WJ, Kastritis E, Gahrton G, Weisel K, Nagarajan C, Schjesvold F, Mikhael J, Costa L, Raje NS, Zamagni E, Hajek R, Weinhold N, Yong K, Ye JC, Sidhana S, Merlini G, Martin T, Lin Y, Chari A, Popat R, Kaufman JLInt Myeloma Working GrpShow more
The Lancet. Oncology
2024 05
KI-anknytning: Låg
Review
The systemic lupus erythematosus-associated NCF190H allele synergizes with viral infection to cause mouse lupus but also limits virus spread
Li YP, Coelho A, Li ZL, Alsved M, Li QX, Xu R, Luo HQ, Liang DX, Xu J, Nandakumar KS, Meng LS, Loendahl J, Holmdahl RShow more
Nature communications
2025 Feb 13
KI-anknytning: Hög
Article
A Latent Cardiomyocyte Regeneration Potential in Human Heart Disease
Derks W, Rode J, Collin S, Rost F, Heinke P, Hariharan A, Pickel L, Simonova I, Lazar E, Graham E, Jashari R, Andra M, Jeppsson A, Salehpour M, Alkass K, Druid H, Kyriakopoulos CP, Taleb I, Shankar TS, Selzman CH, Sadek H, Jovinge S, Brusch L, Frisen J, Drakos S, Bergmann OShow more
Circulation
2025 Jan 21
KI-anknytning: Hög
Article
Suppressing recurrence in Sonic Hedgehog subgroup medulloblastoma using the OLIG2 inhibitor CT-179
Li YC, Lim C, Dismuke T, Malawsky DS, Oasa S, Bruce ZC, Offenhaeuser C, Baumgartner U, D'Souza RCJ, Edwards SL, French JD, Ock LSH, Nair S, Sivakumaran H, Harris L, Tikunov AP, Hwang D, Pauneto CDA, Maybury M, Hassall T, Wainwright B, Kesari S, Stein G, Piper M, Johns TG, Sokolsky-Papkov M, Terenius L, Vukojevic V, Mcswain LF, Gershon TR, Day BWShow more
Nature communications
2025 Feb 04
KI-anknytning: Låg
Article
Evaluating Biparametric Versus Multiparametric Magnetic Resonance Imaging for Diagnosing Clinically Significant Prostate Cancer: An International, Paired, Noninferiority, Confirmatory Observer Study
Twilt JJ, Saha A, Bosma JS, van Ginneken B, Bjartell A, Padhani AR, Bonekamp D, Villeirs G, Salomon G, Giannarini G, Kalpathy-Cramer J, Barentsz J, Maier-Hein KH, Rusu M, Rouviere O, van den Bergh R, Panebianco V, Kasivisvanathan V, Obuchowski NA, Yakar D, Elschot M, Veltman J, Futterer JJ, Huisman H, de Rooij MPI-CAI ConsortiumShow more
European urology
2025 Feb
KI-anknytning:
Article
Simultaneous detection of membrane contact dynamics and associated Ca2+ signals by reversible chemogenetic reporters
Casas PG, Rossini M, Pavenius L, Saeed M, Arnst N, Sonda S, Fernandes T, D'Arsie I, Bruzzone M, Berno V, Raimondi A, Sassano ML, Naia L, Barbieri E, Sigismund S, Agostinis P, Sturlese M, Niemeyer BA, Brismar H, Ankarcrona M, Gautier A, Pizzo P, Filadi RShow more
Nature communications
2024 11 12
KI-anknytning: Medel
Article
The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia model
Dusek J, Mejdrova I, Dohnalova K, Smutny T, Chalupsky K, Krutakova M, Skoda J, Rashidian A, Pavkova I, Skach K, Hricova J, Chocholouskova M, Smutna L, Kamaraj R, Hroch M, Lenicek M, Micuda S, Pijnenburg D, van Beuningen R, Holcapek M, Vitek L, Ingelman-Sundberg M, Burk O, Kronenberger T, Nencka R, Pavek PShow more
Nature communications
2025 Feb 06
KI-anknytning: Låg
Article
Mapping reactive astrogliosis in Parkinson's brain with astroglial tracers BU99008 and Deprenyl: New insights from a multi-marker postmortem study
Rocha FM, Roy A, Varshney M, Kumar AShow more
Alzheimer's & dementia : the journal of the Alzheimer's Association
2025 Feb
KI-anknytning: Hög
Article
Presentation and outcome in carriers of pathogenic variants in SLC34A1 and SLC34A3 encoding sodium-phosphate transporter NPT 2a and 2c
Brunkhorst M, Brunkhorst L, Martens H, Papizh S, Besouw M, Grasemann C, Turan S, Sikora P, Chromek M, Cornelissen E, Fila M, Lilien M, Allgrove J, Neuhaus TJ, Eltan M, Espinosa L, Schnabel D, Gokce I, Gonzalez-Rodriguez JD, Khandelwal P, Keijzer-Veen MG, Lechner F, Szcepanska M, Zaniew M, Bacchetta J, Emma F, Haffner DShow more
Kidney international
2025 Jan
KI-anknytning: Låg
Article

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