Pauliina Elisabet Damdimopoulou
Professor in reproductive biology leading research on chemical impacts on female fertility. Experienced supervisor, educator and scientific ambassador.
About me
I am a Professor of Reproductive Biology at the Department of Women's and Children's Health.
With over 15 years of experience in endocrinology, reproductive biology and toxicology, I lead a research group at Karolinska Institutet that investigates the effects of chemicals on female fertility. My ambition is to generate evidence-based information on the risks of chemical exposures and pharmaceutical treatments to human ovaries and oocytes, and to thereby contribute to the development of a chemically safer society.
I co-lead the Environmental Endocrinology Focus Area of the European Society of Endocrinology, and I serve as the Swedish Ambassador for the European Research Council since 2025.
In addition, I teach and supervise students at various levels, participate in university administration, and engage in stakeholder activities.
I have received multiple grants and honors for my research, have served as a scientific expert for national and international organizations, and I frequently present my work at international conferences.
Research
I'm interested in studying the impact of pharmaceuticals and environmental chemicals on fertility in women, with a special focus on the ovary.
The work of my research group focuses on several aims:
- We assess environmental exposures in women and study their associations with fertility.
- We study the effects of gonadotoxic treatments, like chemotherapy, on ovaries.
- We map the molecular and cellular composition of human ovaries across life.
- We investigate how environmental and pharmaceutical exposures affect ovaries by using tissue culture models.
- We develop new in vitro tools for predicting reproductive toxicity of chemicals.
Teaching
I'm a docent in endocrine physiology (2015, University of Turku, Finland) and toxicology (2021, Karolinska Institutet) with teaching experience in various MSc and PhD courses at different universities in Sweden and Finland.
I have supervised over 20 undergraduate students and MSc thesis projects. I have also served as the main supervisor for five PhD students, guiding them to successful graduations. I have formal training in higher education pedagogy, leadership, and the supervision of doctoral students.
Articles
- Article: JOURNAL OF OVARIAN RESEARCH. 2026;19(1):79Deligiannis SP; Li T; Moussaud-Lamodiere E; Vegvari A; Damdimopoulos A; Lavogina D; Papaikonomou K; Zubarev R; Acharya G; Velthut-Meikas A; Damdimopoulou P; Salumets A; Di Nisio V
- Article: JOURNAL OF OBSTETRICS AND GYNAECOLOGY. 2025;45(1):2463419Alder S; Papaikonomou K; Tebani L; Rooda I; Dhejne C; Damdimopoulou P; Gidlöf S
- Article: JOURNAL OF OVARIAN RESEARCH. 2025;19(1):15Knuus K; Nguyen M; Hannula M; Hassan J; Otala M; Tuuri T; Lundin K; Lahtinen A; Damdimopoulou P; Hyttinen J; Jahnukainen K
- Article: REPRODUCTIVE BIOMEDICINE ONLINE. 2025;51(3):104988Assessing the ovarian microbiome: lack of a distinguishable microbial signature beyond contaminationSola-Leyva A; Perez-Prieto I; Di Nisio V; Panagiotis-Deligiannis S; Blanco-Rodriguez L; Acharya G; Saare M; Papaikonomou K; Damdimopoulou P; Salumets A; Altmae S
- Article: ENVIRONMENTAL RESEARCH. 2025;279(Pt 1):121797Nikanfar S; Leonel ECR; Damdimopoulou P; Flaws JA; Amorim CA
- Article: REPRODUCTIVE TOXICOLOGY. 2025;135:108938Laws MJ; Kramer S; Gonyea T; Huff J; Edwards L; Tarvainen I; Damdimopoulou P; Flaws JA
- Journal article: REPRODUCTIVE TOXICOLOGY. 2025;135:108938Laws MJ; Kramer S; Gonyea T; Huff J; Edwards L; Tarvainen I; Damdimopoulou P; Flaws JA
- Article: TOXICOLOGICAL SCIENCES. 2025;206(1):30-45Silva AV; Tarvainen I; Oberg M; Laws M; Hannon P; Flaws J; Damdimopoulou P
- Article: HUMAN REPRODUCTION OPEN. 2025;2025(3):hoaf042Di Nisio V; Li T; Xiao Z; Papaikonomou K; Damdimopoulos A; Vegvari A; Lebre F; Alfaro-Moreno E; Pedersen M; Svingen T; Zubarev R; Acharya G; Damdimopoulou P; Salumets A
- Journal article: HUMAN REPRODUCTION. 2025;40:deaf097.708Deligiannis SP; Li T; Moussaud-Lamodiere E; Lavogina D; Papaikonomou K; Damdimopoulou P; Salumets A; Di Nisio V
- Journal article: ENVIRONMENTAL ENDOCRINOLOGY. 2025;1(1)Köhrle J; Damdimopoulou P; Nadal A
- Journal article: REPRODUCTIVE, FEMALE AND CHILD HEALTH. 2025;4(1)Rooda I; Alder S; Tebani L; Gidlöf S; Arnelo C; Pettersson K; Damdimopoulou P
- Article: CURRENT RESEARCH IN TOXICOLOGY. 2025;9:100257Draskau MK; Spiller CM; Panagiotou EM; Zilliacus J; Beronius A; Damdimopoulou P; Bowles J; Svingen T
- Article: REPRODUCTIVE TOXICOLOGY. 2024;130:108733Lavogina D; Kask K; Kopanchuk S; Visser N; Laws M; Flaws JA; Kallak TK; Olovsson M; Damdimopoulou P; Salumets A
- Article: ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. 2024;43(11):2329-2337Draskau MK; Rosenmai AK; Bouftas N; Johansson HKL; Panagiotou EM; Holmer ML; Elmelund E; Zilliacus J; Beronius A; Damdimopolou P; van Duursen M; Svingen T
- Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2024;(212)Hassan J; Damdimopoulou P; Lahtinen A; Jahnukainen K; Knuus K; Acharya G; Bjorvang RD
- Article: REPRODUCTIVE TOXICOLOGY. 2024;128:108660Visser N; Silva AV; Tarvainen I; Damdimopoulos A; Davey E; Roos K; Bjorvang RD; Kallak TK; Lager S; Lavogina D; Laws M; Piltonen T; Salumets A; Flaws JA; Oberg M; Velthut-Meikas A; Damdimopoulou P; Olovsson M
- Article: ENVIRONMENT INTERNATIONAL. 2024;191:108960Varik I; Zou R; Bellavia A; Rosenberg K; Sjunnesson Y; Hallberg I; Holte J; Lenters V; Van Duursen M; Pedersen M; Svingen T; Vermeulen R; Salumets A; Damdimopoulou P; Velthut-Meikas A
- Journal article: TOXICOLOGY LETTERS. 2024;399:s193Silva AV; Flaws J; Laws M; Oberg M; Damdimopoulou P
- Journal article: TOXICOLOGY LETTERS. 2024;399:s8-s9Damdimopoulou PE
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All other publications
- Dataset: KI DATA REPOSITORY. 2026Li T; Wehrli L; Antonouli S; Panagiotou EM; Deligiannis SP; Liu X; Hassan J; Moussaud-Lamodière E; Arnelo C; Pettersson K; Papaikonomou K; Salumets A; Damdimopoulou P; Di Nisio V
- Dataset: KI DATA REPOSITORY. 2026Rooda I; Damdimopoulou P
- Review: REPRODUCTIVE TOXICOLOGY. 2026;139:109105Bouftas N; Rosenmai AK; Panagiotou EM; Zilliacus J; Damdimopoulou P; Beronius A; van Duursen M; Svingen T
- Dataset: KI DATA REPOSITORY. 2025Deligiannis SP; Li T; Moussaud-Lamodière E; Végvári A; Damdimopoulos A; Lavogina D; Damdimopoulou K; Zubarev R; Acharya G; Velthut-Meikas A; Damdimopoulou P; Salumets A; Di Nisio V
- Review: JOURNAL OF INTERNAL MEDICINE. 2025;298(6):532-561Wehrli L; Martin OV; Trasande L; Damdimopoulou P
- Review: NATURE REVIEWS ENDOCRINOLOGY. 2025;21(10):593-607Parent A-S; Damdimopoulou P; Johansson HKL; Bouftas N; Draskau MK; Franssen D; Fudvoye J; van Duursen M; Svingen T
- Dataset: KI DATA REPOSITORY. 2025Di Nisio V; Li T; Xiao Z; Papaikonomou K; Damdimopoulos A; Végvári Á; Lebre F; Alfaro-Moreno E; Pedersen M; Svingen T; Zubarev R; Acharya G; Damdimopoulou P; Salumets A
- Review: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2025;232(4):s95.e1-s95.e16Rooda I; Mear L; Hassan J; Damdimopoulou P
- Preprint: BIORXIV. 2025Deligiannis SP; Li T; Moussaud-Lamodière E; Végvári A; Damdimopoulos A; Lavogina D; Papaikonomou K; Zubarev R; Acharya G; Velthut-Meikas A; Damdimopoulou P; Salumets A; Nisio VD
- Preprint: BIORXIV. 2024Di Nisio V; Li T; Xiao Z; Papaikonomou K; Damdimopoulos A; Végvári Á; Lebre F; Alfaro-Moreno E; Pedersen M; Svingen T; Zubarev R; Acharya G; Damdimopoulou P; Salumets A
- Conference publication: HUMAN REPRODUCTION. 2024;39Nikanfar S; Leonel ECR; Damdimopoulou P; Flaws JA; Bento EA; Amorim CA
- Preprint: BIORXIV. 2024Lavogina D; Kask K; Kopanchuk S; Visser N; Laws M; Flaws J; Kallak TK; Olovsson M; Damdimopoulou P; Salumets A
- Conference publication: REPRODUCTIVE SCIENCES. 2024;31:296AVisser N; Lavogina D; Tarvainen I; Kallak TK; Lager S; Bjorvang RD; Laws M; Flaws J; Salumets A; Damdimopoulou P; Olovsson M
- Editorial: NATURE REVIEWS ENDOCRINOLOGY. 2024;20(4):187-188Reincke M; Arlt W; Damdimopoulou P; Koehrle J; Bertherat J
- Conference publication: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2023;102:65Visser N; Damdimopoulos A; Davey E; Kallak TK; Lager S; Velthut-Meikas A; Roos K; Bjorvang RD; Lavogina D; Laws M; Chowdhury A; Bergsten P; Salumets A; Flaws J; Damdimopoulou P; Olovsson M; Tarvainen I
- Conference publication: TOXICOLOGY LETTERS. 2023;384:s77-S80Zilliacus J; Draskau MK; Johansson HK; Rosenmai AK; Christiansen S; Elmelund E; Holmer ML; Damdimopoulou P; Panagiotou EM; van Duursen M; Bouftas N; Svingen T; Beronius A
- Conference publication: TOXICOLOGY LETTERS. 2023;384:S77Zilliacus J; Draskau MK; Johansson HK; Rosenmai AK; Christiansen S; Elmelund E; Holmer ML; Damdimopoulou P; Panagiotou EM; van Duursen M; Bouftas N; Svingen T; Beronius A
- Conference publication: TOXICOLOGY LETTERS. 2023;384:S192-S193Vazakidou P; Li T; Lecante LL; Mazaud-Guittot S; Fowler PA; Damdimopoulou P; Leonards P; van Duursen M
- Conference publication: HUMAN REPRODUCTION. 2023;38Varik I; Roos K; Bellavia A; Zou R; Bjorvang RD; Sjunnesson Y; Hallberg I; Holte J; Pikki A; Lenters V; Van Duursen M; Vermeulen R; Salumets A; Damdimopoulou P; Velthut-Meikas A
- Conference publication: HUMAN REPRODUCTION. 2023;38Hao J; Li T; Damdimopoulos A; Sjodin M; Lindberg J; Pettersson K; Hovatta O; Damdimopoulou P
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Grants
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2022 - 31 December 2026We are constantly exposed to a complex mixture of endocrine-disrupting chemicals (EDCs) and other chemicals with unknown effects on the reproductive system. EDCs have been suspected to impair fertility but it is impossible to test all substances individually and effects are likely to be additive or even synergistic. The oocyte is surrounded by follicular fluid that influences the potential of the oocyte to mature, become fertilized and develop into a new individual. In this project we will investigate in vitro oocyte maturation and early embryo development after the addition of a mixture extracted from in vivo collected follicular fluid from women undergoing fertility treatment (n=160). The aim is to use an effects-directed approach to identify harmful substances in follicular fluid. We will pool the follicular fluid according to poor or good embryo quality as recorded during fertility treatment. After extraction and concentration, it will be added to the medium during bovine oocyte maturation in vitro, a model well suited for comparisons with human in vitro fertilization procedures. Oocytes and embryos will be closely examined and the fraction found likely to disturb maturation or embryo development will be analysed using a non-target screening approach to reveal the fraction composition. By this top-bottom approach we hope to gain information that in time can be used for legislative purposes to reduce the harmful exposure.
- Swedish Research Council1 January 2021 - 31 December 2023
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2021 - 31 December 2024
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 December 2018 - 30 November 2024
- Swedish Research Council1 January 2018 - 31 December 2019
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2018 - 31 December 2021
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2016 - 31 December 2018
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2016 - 31 December 2018
- Swedish Research Council1 January 2010 - 31 December 2010
Employments
- Professor, Department of Women's and Children's Health, Karolinska Institutet, 2025-
- Senior Lecturer, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 2022-2025
- Postdoctoral researcher, R&D, Watchfrog (France), 2008-2010
Degrees and Education
- Docent, Karolinska Institutet, 2021