Venkatesh Chellappa
Bioinformatics Lead and PhD candidate at Karolinska Institutet specializing in genome informatics and bioinformatics. Over 15 years of experience architecting HPC infrastructure, DevOps pipelines (Nex
About me
I am a Bioinformatician and Doctoral Candidate in the Prostate Cancer Genomics group at the Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet. My doctoral research focuses on cancer genomics, bioinformatics, machine learning and data science for analysis of high-rhoughput sequencing data.
2021 - present - Doctoral Student (Medical Sciences) - Cancer Genomics, Bioinformatics, KI, Stockholm, Sweden
2010 - Master of Science in Biosystems & Informatics, Liverpool, UK
2006 - Bachelor of Veterinary Sciences & Animal Husbandry, Pondicherry, India
Research
My work centers on developing scalable computational pipelines (Snakemake, Nextflow) to analyze high-throughput sequencing data across cancer genomics and transcriptomics. I am particularly interested in applying machine learning and AI to integrate multi-omics data, driving deeper insights into high-penetrance cancers.
/Tags: Cancer Genomics • Liquid Biopsy (cfDNA/ctDNA) • Nextflow & Snakemake • HPC & Cloud Infrastructure • CI/CD & DevOps • ML/AI for Omics • Containerization & Orchestration: Docker • Singularity / Apptainer • Kubernetes • Clinical Bioinformatic Pipelines/
Teaching
Lab assistant - Clinical Cancer Genomics course at MEB, KI.
Articles
- Article: JOURNAL OF MOLECULAR DIAGNOSTICS. 2026;28(2):187-198Wallander K; Lin Y; Ivanchuk V; Difilippo V; Chellappa V; Murugan SK; Ofverholm I; Branstrom R; Nord KH; Carlson J; De Flon FH
- Article: NEW ENGLAND JOURNAL OF MEDICINE. 2025;393(11):1051-1064Martling A; Hed Myrberg I; Nilbert M; Gronberg H; Granath F; Eklund M; Oresland T; Iversen LH; Haapamaki C; Janson M; Westberg K; Segelman J; Ersson U; Prytz M; Angenete E; Bergstrom R; Mayrhofer M; Glimelius B; Lindberg J
- Article: CANCERS. 2024;16(22):3816Ofverholm I; Lin Y; Mondini J; Hardingz J; Braenstroem R; Tsagkozis P; Wirta V; Gellerbring A; Lindberg J; Chellappa V; Mayrhofer M; Haglund C; Haglund de Flon F; Wallander K
- Article: NATURE MEDICINE. 2024;30(11):3291-3302De Laere B; Crippa A; Discacciati A; Larsson B; Persson M; Johansson S; D'hondt S; Bergstrom R; Chellappa V; Mayrhofer M; Banijamali M; Kotsalaynen A; Schelstraete C; Vanwelkenhuyzen JP; Hjalm-Eriksson M; Pettersson L; Ullen A; Lumen N; Enblad G; Thellenberg Karlsson C; Janes E; Sandzen J; Schatteman P; Vigmostad M; Olsson M; Ghysel C; Sautois B; De Roock W; Van Bruwaene S; Anden M; Verbiene I; De Maeseneer D; Everaert E; Darras J; Aksnessether BY; Luyten D; Strijbos M; Mortezavi A; Oldenburg J; Ost P; Eklund M; Gronberg H; Lindberg J
- Article: CLINICAL CANCER RESEARCH. 2024;30(12):2647-2658Ofverholm I; Wallander K; Haglund C; Chellappa V; Wejde J; Gellerbring A; Wirta V; Renevey A; Caceres E; Tsagkozis P; Mayrhofer M; Papakonstantinou A; Linder-Stragliotto C; Branstrom R; Larsson O; Lindberg J; Lin Y; de Flon FH
- Article: EUROPEAN UROLOGY FOCUS. 2023;9(3):455-462Palsdottir T; Gronberg H; Hilmisson A; Eklund M; Nordstrom T; Vigneswaran HT
- Journal article: ESMO OPEN. 2023;8(1):101095Wallander KM; Öfverholm I; Yingbo L; Haglund C; Chellappa V; Tsagkozis P; Hesla A; Papakonstantinou A; Bränström R; Wirta V; Lindberg J; de Flon FH
- Article: JOURNAL OF HUMAN GENETICS. 2023;68(1):39-46Janani DM; Ramasubramanyan S; Chellappa V; Santhanam R; Manickam R; Shameli J; Balasundaram U
- Article: EUROPEAN UROLOGY OPEN SCIENCE. 2022;41:1-7Engel JC; Palsdottir T; Ankerst D; Remmers S; Mortezavi A; Chellappa V; Egevad L; Gronberg H; Eklund M; Nordstrom T
- Article: PROSTATE. 2022;82(5):576-583Lindh C; Samaratunga H; Delahunt B; Bergstrom R; Chellappa V; Yaxley J; Lindberg J; Egevad L
- Article: FRONTIERS IN GENETICS. 2022;13:820493Deng W; Murugan S; Lindberg J; Chellappa V; Shen X; Pawitan Y; Vu TN
- Journal article: EUROPEAN UROLOGY OPEN SCIENCE. 2021;33:s216-s217Engel JC; Palsdottir T; Ankerst D; Remmers S; Mortezavi A; Chellappa V; Egevad L; Grönberg H; Eklund M; Nordström T
- Article: EUROPEAN UROLOGY FOCUS. 2021;7(3):546-553Mortezavi A; Palsdottir T; Eklund M; Chellappa V; Murugan SK; Saba K; Ankerst DP; Haug ES; Nordstrom T; Tilki D
All other publications
- Conference publication: EUROPEAN JOURNAL OF HUMAN GENETICS. 2025;33:1161-1162Lyander A; Kyriakidis V; Chellappa V; Bergstrom R; Hagglund M; Lindberg J
- Corrigendum: NATURE MEDICINE. 2024;30(11):3381De Laere B; Crippa A; Discacciati A; Larsson B; Persson M; Johansson S; D'hondt S; Bergstrom R; Chellappa V; Mayrhofer M; Banijamali M; Kotsalaynen A; Schelstraete C; Vanwelkenhuyzen JP; Hjaelm-Eriksson M; Pettersson L; Ullen A; Lumen N; Enblad G; Karlsson CT; Jaenes E; Sandzen J; Schatteman P; Vigmostad MN; Olsson M; Ghysel C; Sautois B; De Roock W; Van Bruwaene S; Anden M; Verbiene I; De Maeseneer D; Everaert E; Darras J; Aksnessether BY; Luyten D; Strijbos M; Mortezavi A; Oldenburg J; Ost P; Eklund M; Gronberg H; Lindberg J
- Preprint: MEDRXIV. 2024Mayrhofer M; Bergström R; Chellappa V; Kotsalaynen A; Murugan S; Crippa A; De Laere B; Urtishak K; Sorensen KD; Garg K; Singh U; Eklund M; Grönberg H; Lindberg J
Employments
- Bioinformatician, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2018-
- Phd Student, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2021-2027
Degrees and Education
- Bachelor of Veterinary Sciences & Animal Husbandry, Veterinary Medicine & Surgery, Epidemiological Report of Trypanosomosis in Captive Wild Animals of India, Pondicherry Veterinary College, Pondicherry University, 2006