Thomas Kahan

About me
Publications
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About me

Senior consultant in cardiolgy at the Department of cardiology, Danderyd
University Hospital
MD at Karolinska Institutet, PhD in pharmacology at Karolinska Institutet.
Profssor in medicine. Board certified specialist in internal medicine and
caridolgy, working as clinical cardiolgist.

Research

My main research interests are related to neurohormonal mechanisms in the
control of blood pressure and cardiac function, with a focus on structural
myocardial and vascular changes in hypertension, hypertesive heart disease,
the transition from hypertension to heart failure, and on neuroendocrine
regulatory mechanisms in heart failure. In particular, we study effects of
the sympathetic nervous system and the renin-angiotensin-aldosterone system
in this context. Other areas of interest are cardiovacular risk assesment and
prevention, and health economics and implementation of treatment.

Articles

Journal article: AMERICAN JOURNAL OF PREVENTIVE CARDIOLOGY. 2026;28:101573
Associations between prediabetes, type 2 diabetes and incident atrial fibrillation in patients with hypertension: Results from the Swedish Primary Care Cardiovascular Database
Bentzel S; Andersson T; Ljungman C; Johansson JSM; Hjerpe P; Schioler L; Ravn-Fischer A; Bostrom KB; Kahan T; Mourtzinis G
Article: EUROPEAN HEART JOURNAL. 2026;:ehag494
Artificial Intelligence in Biomedical Scientific Publishing.
Guzik TJ; Aboyans V; Agewall S; Bailey S; Baranchuk A; Bäck M; Böhm M; Bonow RO; Booz GW; Boriani G; Bozkurt B; Bruining N; Capodanno D; Erol Ç; Ferdinandy P; Gimelli A; Heusch G; Kahan T; Lang CC; Maurer G; Mentz RJ; Metra M; Moons P; Piskorz D; Piepoli M; Ponikowski P; Popma A; Rocca B; Fores JS; Sommer P; Touyz RM; Ungvari Z; Vranckx P; Hill JA; Lüscher TF; Crea F
Journal article: JOURNAL OF HYPERTENSION. 2026;44(SUPPL 1):e206
SUSTAINED 5-YEAR BLOOD PRESSURE REDUCTION BY RADIOFREQUENCY RENAL DENERVATION IN UNCONTROLLED HYPERTENSION: THE SWEDISH REGISTRY FOR RENAL DENERVATION
Jekell A; Landstedt K; Spaak J; Kahan T
Article: BMC MEDICAL INFORMATICS AND DECISION MAKING. 2026;26(1):126
A machine learning model to simplify recognition of patients with atrial fibrillation based on diagnostic codes in Swedish primary health care
Norrman A; Wachtler C; Wandell P; Eriksson J; Ruge T; Brynedal B; Hasselstrom J; Kahan T; Carlsson AC
Article: HELICOBACTER. 2026;31(2):e70116
Helicobacter pylori, Inflammation, and Long-Term Outcome in Patients With Acute Myocardial Infarction: A Prospective Cohort Study
Sundqvist MO; Warme J; Hjort M; Tornvall P; Jernberg T; Lindahl B; Schiopu A; Baron T; Jacobson SH; Kahan T; Erlinge D; Spaak J; Hofmann R
Article: JOURNAL OF MEDICAL INTERNET RESEARCH. 2026;28:e76087
Computerized Self-Reported Medical History Taking to Support Early Rule Out of Major Adverse Cardiac Events in Patients With Acute Chest Pain: Post Hoc Analysis of the CLEOS-CPDS Prospective Cohort Study
Brandberg H; Sundberg CJ; Spaak J; Koch S; Kahan T
Article: BLOOD PRESSURE. 2025;34(1):2487583
Cost-effectiveness analysis of radiofrequency renal denervation for uncontrolled hypertension in Sweden
Kahan T; Johansen ML; Ryschon AM; Cao KN; Kolovetsios MD; Lindgren P; Pietzsch JB
Article: EUROPEAN HEART JOURNAL OPEN. 2025;5(6):oeaf138
Prevalence and prediction of masked uncontrolled hypertension in patients recently hospitalized for myocardial infarction.
Hellqvist H; Erlinge D; Lindahl B; Jernberg T; Oldgren J; James S; Al-Khalili F; Kahan T; Spaak J
Journal article: EUROPEAN HEART JOURNAL OPEN. 2025;5(6):oeaf138
Prevalence and prediction of masked uncontrolled hypertension in patients recently hospitalized for myocardial infarction
Hellqvist H; Erlinge D; Lindahl B; Jernberg T; Oldgren J; James S; Al-Khalili F; Kahan T; Spaak J
Article: SCIENTIFIC REPORTS. 2025;15(1):37733
Circulating vascular biomarkers in relation to physiological indices of aortic stiffness and endothelial function in hypertension
Jekell A; Ekholm M; Kahan T; Lundwall K
Article: HEART AND VESSELS. 2025;40(10):895-904
Overnight stiffness index from finger photoplethysmography in relation to markers of cardiovascular risk and vascular ageing
Hellqvist H; Rietz H; Grote L; Hedner J; Sommermeyer D; Kahan T; Spaak J
Article: ANNALS OF EPIDEMIOLOGY. 2025;108:56-62
The definition of treatment assignment in observational emulations of target trials - an empirical examination in the Swedish Primary Care Cardiovascular Database
Humphreys ABC; Matthews AA; Young JC; Berglund A; Lindahl B; Wettermark B; Dahabreh IJ; Kahan T; Hernan MA
Article: JMIR MEDICAL INFORMATICS. 2025;13:e65568
Patient Perspectives on Digital Technology and Experiences of Computerized History-Taking for Chest Pain Management in the Emergency Department: CLEOS-CPDS Prospective Cohort Study
Fritzell K; Brandberg H; Spaak J; Koch S; Sundberg CJ; Zakim D; Kahan T; Sundberg K
Journal article: JOURNAL OF HYPERTENSION. 2025;43(SUPPL 1):e99
DIGIT PREFERENCE OF SYSTOLIC OR DIASTOLIC BLOOD PRESSURE AND THE ASSOCIATION WITH CARDIOVASCULAR EVENTS IN PATIENTS WITH TREATED HYPERTENSION IN PRIMARY CARE
Anders N; Linus S; Carlsson CA; Bengtsson BK; Per H; Charlotta L; Miriam Q; Per W; Thomas K; Jan H
Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2025;34(1):e70075
Have People Treated With Antihypertensives Been Diagnosed With Hypertension? A Cross-Sectional Study in Stockholm, Sweden
Treciokiene I; Forslund T; Kahan T; Taxis K; Wettermark B
Article: EUROPEAN JOURNAL OF INTERNAL MEDICINE. 2025;131:58-64
The impact of the COVID-19 Pandemic on hypertension phenotypes (ESH ABPM COVID-19 study).
Ostrowska A; Wojciechowska W; Rajzer M; Weber T; Bursztyn M; Persu A; Stergiou G; Kiełbasa G; Chrostowska M; Doumas M; Parati G; Bilo G; Grassi G; Mancia G; Januszewicz A; Kreutz R; ESH ABPM COVID-19 Study Investigators
Article: RESUSCITATION PLUS. 2025;21:100839
Exploring the impact of age on the predictive power of the National Early Warning score (NEWS) 2, and long-term prognosis among patients reviewed by a Rapid Response Team: A prospective, multi-centre study
Thoren A; Franko MA; Joelsson-Alm E; Rawshani A; Kahan T; Engdahl J; Jonsson M; Djarv T; Spangfors M
Article: BLOOD PRESSURE. 2024;33(1):2368800
Management of patients with hypertension and chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. On behalf of the European Society of Hypertension Working Group on Hypertension and the Kidney
Halimi J-M; Sarafidis P; Azizi M; Bilo G; Burkard T; Bursztyn M; Camafort M; Chapman N; Cottone S; de Backer T; Deinum J; Delmotte P; Dorobantu M; Doumas M; Dusing R; Duly-Bouhanick B; Fauvel J-P; Fesler P; Gaciong Z; Gkaliagkousi E; Gordin D; Grassi G; Grassos C; Guerrot D; Huart J; Izzo R; Aguila FJ; Jarai Z; Kahan T; Kantola I; Kocianova E; Limbourg F; Lopez-Sublet M; Mallamaci F; Manolis A; Marketou M; Mayer G; Mazza A; MacIntyre I; Mourad J-J; Muiesan ML; Nasr E; Nilsson P; Oliveras A; Ormezzano O; Paixao-Dias V; Papadakis I; Papadopoulos D; Perl S; Polonia J; Pontremoli R; Pucci G; Robles NR; Rubin S; Ruilope LM; Rump LC; Saeed S; Sanidas E; Sarzani R; Schmieder R; Silhol F; Sokolovic S; Solbu M; Soucek M; Stergiou G; Sudano I; Tabbalat R; Tengiz I; Triantafyllidi H; Tsioufis K; Vaclavik J; van der Giet M; Van der Niepen P; Veglio F; Venzin R; Viigimaa M; Weber T; Widimsky J; Wuerzner G; Zelveian P; Zebekakis P; Lueders S; Persu A; Kreutz R; Vogt L
Article: PLATELETS. 2024;35(1):2437768
Alterations in platelet activity and endothelial glycocalyx biomarkers by treatment with an angiotensin converting enzyme inhibitor or an alpha-1 adrenoceptor antagonist in patients with hypertension: results from the DoRa study
Ekholm M; Jekell A; Lundwall K; Alfredsson J; Lindahl TL; Wallen H; Kahan T
Article: JOURNAL OF HYPERTENSION. 2024;42(12):2065-2074
The impact of the COVID-19 pandemic on blood pressure control in patients with treated hypertension-results of the European Society of Hypertension Study (ESH ABPM COVID-19 Study)
Wojciechowska W; Rajzer M; Kreutz R; Weber T; Bursztyn M; Persu A; Stergiou G; Parati G; Bilo G; Pac A; Grassi G; Mancia G; Januszewicz A; Chrostowska M; Narkiewicz K; Dubiela A; Doumas M; Imprialos K; Stavropoulos K; de Freminville J-B; Azizi M; Cunha PG; Lewandowski J; Strzelczyk J; Wuerzner G; Gosk-Przybylek M; Szwench-Pietrasz E; Prejbisz A; Van der Niepen P; Kahan T; Jekell A; Spaak J; Tsioufis K; Ehret G; Doroszko A; Kubalski P; Polonia J; Styczkiewicz K; Styczkiewicz M; Mazur S; Veglio F; Rabbia F; Eula E; Aguila FJ; Sarzani R; Spannella F; Jarai Z; Papadopoulos D; Lopez-Sublet M; Ostrowska A; Grassos C; Kahrimanidis I; Eugenia G; Areti T; Tomasz G; Barbara W; Aleksandra S; Beata M; Angeliki N; Robles NR; Widmiski J; Zbroch E
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All other publications

Letter: HEART AND VESSELS. 2026;41(6):438-439
Reply to the comments regarding "Overnight stiffness index from finger photoplethysmography in relation to markers of cardiovascular risk and vascular ageing"
Hellqvist H; Kahan T; Spaak J
Review: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. 2026;33(7):1058-1071
Cuffless Blood Pressure Monitoring Devices: Technical Foundations and Clinical Implications
Parati G; Ochoa JE; Abreu A; Brouwers S; Bruno RM; Caiani EG; Casado-Arroyo R; Cluitmans M; Davos CH; De Lucia R; Dilaveris P; Guerra F; Hanssen H; Jensen MT; Kahan T; Kemps H; Leeson P; Locati ET; Lumens J; Mahfoud F; Roig JM; Omboni S; Papaioannou TG; Platonov PG; Ramirez J; Schuuring MJ; Sudano I; Treskes RW; Avolio A; Castiglioni P
Editorial: EUROPEAN HEART JOURNAL OPEN. 2026;6(2):oeag074
First quinquennium completed: highlights from EHJ Open 2025
Back M; Banach M; Braunschweig F; De Rosa S; Flachskampf FA; Kahan T; Ketelhuth DFJ; Lancellotti P; Larsson SC; Mellbin L; Savarese G; Jensen AS; Szummer K; Wahl D
Conference publication: EUROPEAN HEART JOURNAL. 2025;46
Associations between prediabetes and diabetes mellitus type 2 and incident atrial fibrillation in patients with hypertension; results from the Swedish Primary Care Cardiovascular Database
Bentzel S; Andersson T; Ljungman C; Johansson J; Hjerpe P; Schioler L; Ravn-Fischer A; Bengtsson Bostrom K; Kahan T; Mourtzinis G
Preprint: JMIR PREPRINTS. 2025
Computerized Self-Reported Medical History Taking to Support Early Rule Out of Major Adverse Cardiac Events in Patients With Acute Chest Pain: Post Hoc Analysis of the CLEOS-CPDS Prospective Cohort Study (Preprint)
Brandberg H; Sundberg CJ; Spaak J; Koch S; Kahan T
Corrigendum: JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION. 2025;32(1):261-263
Are medical history data fit for risk stratification of patients with chest pain in emergency care? Comparing data collected from patients using computerized history taking with data documented by physicians in the electronic health record in the CLEOS-CPDS prospective cohort study (vol 31, pg 1529, 2024)
Brandberg H; Sundberg CJ; Spaak J; Koch S; Kahan T
Other: BLOOD PRESSURE. 2024;33(1):2317263
Why were the 2023 Guidelines of the European Society of Hypertension not developed as Joint Guidelines together with the European Society of Cardiology?
Kreutz R; Azizi M; Grassi G; Januszewicz A; Kahan T; Lurbe E; Polonia J; Tsioufis K; Weber T; Williams B; Mancia G
Editorial: EUROPEAN HEART JOURNAL OPEN. 2024;5(1):oeaf015
Intervention, improved prevention, imaging, inflammation, and innovation: the five I's cardiovascular highlights in EHJ Open 2024
Back M; Banach M; Braunschweig F; De Rosa S; Flachskampf FA; Kahan T; Ketelhuth DFJ; Lancellotti P; Larsson SC; Mellbin L; Savarese G; Jensen AS; Szummer K; Wahl D
Conference publication: EUROPEAN HEART JOURNAL. 2024;45:ehae666.2566
Prevalence and prediction of masked uncontrolled hypertension in patients recently hospitalised for an acute coronary syndrome
Hellqvist H; Erlinge D; Lindahl B; Jernberg T; Oldgren J; James S; Al-Khalili F; Kahan T; Spaak J
Preprint: JMIR PREPRINTS. 2024
Patient perspectives on digital technology and experiences of computerized history taking for chest pain management in the emergency department: The CLEOS-CPDS prospective cohort study (Preprint)
Fritzell K; Brandberg H; Spaak J; Koch S; Sundberg CJ; Zakim D; Kahan T; Sundberg K
Conference publication: JOURNAL OF HYPERTENSION. 2024;42:e74-e75
BLOOD PRESSURE DIGIT PREFERENCE IN HYPERTENSIVE PATIENTS ATTENDING PRIMARY HEALTH CARE IS ASSOCIATED WITH FUTURE CARDIOVASCULAR EVENTS
Norrman A; Schioeler L; Carlsson AC; Bostroem KB; Hjerpe P; Ljungman C; Mourtzinis G; Qvarnstroem M; Wettermark B; Waendell P; Kahan T; Hasselstroem J
Meeting abstract: JOURNAL OF HYPERTENSION. 2024;42:e2-e3
PREDICTING NEW CASES OF HYPERTENSION IN PRIMARY CARE WITH A MACHINE LEARNING TOOL
Norrman A; Hasselstroem J; Ljunggren G; Wachtler C; Eriksson J; Kahan T; Waendell P; Gudjonsdottir H; Lindblom S; Ruge T; Rosenblad A; Brynedal B; Carlsson AC
Conference publication: VALUE IN HEALTH. 2023;26(12):S196-S197
COST-EFFECTIVENESS OF RENAL DENERVATION FOR UNCONTROLLED HYPERTENSION: AN ANALYSIS FOR SWEDEN BASED ON THE SPYRAL HTN-ON MED TRIAL AND OTHER CONTEMPORARY EVIDENCE
Kahan T; Johansen ML; Ryschon AM; Cao K; Kolovetsios M; Lindgren P; Pietzsch J
Conference publication: EUROPEAN HEART JOURNAL. 2023;44:ehad655.2955
Early rule-out of major adverse cardiac events in acute chest pain patients using a risk score and self-reported computerised history taking
Brandberg H; Spaak J; Sundberg CJ; Koch S; Zakim D; Kahan T
Conference publication: JOURNAL OF HYPERTENSION. 2023;41:E68
PARACETAMOL AND BLOOD PRESSURE CONTROL IN 45211 PATIENTS TREATED FOR HYPERTENSION: A CROSS-SECTIONAL STUDY FROM THE SWEDISH PRIMARY CARE CARDIOVASCULAR DATABASE
Gottlieb H; Sundstrom A; Bostrom KB; Hasselstrom J; Hjerpe P; Ljungman C; Manhem K; Mourtzinis G; Qvarnsstrom M; Wettermark B; Kahan T
Editorial: EUROPEAN HEART JOURNAL OPEN. 2022;2(6):oeac084
Highlights from 2022 in EHJ Open
Back M; Banach M; Braunschweig F; De Rosa S; Gimelli A; Kahan T; Ketelhuth DFJ; Lancellotti P; Larsson SC; Mellbin L; Nagy E; Savarese G; Szummer K; Wahl D
Conference publication: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2022;33(11):530
Impact of Kidney Function on the Association Between Selected Proteomic Biomarkers and Cardiovascular Events and Mortality
Salzinger B; Lundwall K; Evans M; Mortberg JL; Wallen H; Jernberg T; Kahan T; Lundman P; Lindahl B; Spaak J; Jacobson SH
Conference publication: EUROPEAN JOURNAL OF HEART FAILURE. 2022;24:240
Prediabetes and incident heart failure in hypertensive patients
Johansson J; Schioler L; Mourtzinis G; Hjerpe P; Bostrom KB; Kahan T; Ljungman C
Conference publication: JOURNAL OF HYPERTENSION. 2022;40(SUPPL):E257
AORTIC STIFFNESS ASSESSED BY HIGH-RESOLUTION PHOTOPLETHYSMOGRAPHY AND SINGLE-LEAD ECG
Hellqvist H; Karlsson M; Kahan T; Spaak J
Conference publication: JOURNAL OF HYPERTENSION. 2022;40(SUPPL):E257
AORTIC STIFFNESS ASSESSED BY HIGH-RESOLUTION PHOTOPLETHYSMOGRAPHY AND SINGLE-LEAD ECG
Hellqvist H; Karlsson M; Kahan T; Spaak J
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Employments

Professor Emeritus, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, 2024-2027
Adjunct Professor, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, 2013-2019
Adjunct Professor, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, 2007-2013

Supervision

Supervision to doctoral degree
- Sami El Amrani, Artificial intelligence in acute chest pain management, 2025-
- Henrik Hellqvist, Assessment of arterial stiffness in populations at increased cardiovascular risk, 2025
- Helge Brandberg, Computerized, patient-entered medical histories to improve the management of patients with acute chest pain, 2024
- Jenny Berg, Utilities and quality of life in cardiovascular diseases – drivers, clinical outcomes and economic effects., 2014
- Jonas Schwieler, 1993

About me

Research

Articles

All other publications

Employments

Supervision

Supervision to doctoral degree

News from KI

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