Tessa Schillemans
About me
I am a postdoctoral researcher in the Division of Family Medicine and Primary Care at the Department of Neurobiology, Care Sciences and Society (NVS). My current research is focused on chronic pain and cardiovascular disease. We are using several large Swedish cohort and register databases to investigate associations of self-reported musculoskeletal pain or pain diagnoses such as fibromyalgia, rheumatoid arthritis and osteoporosis and cardiovascular outcomes. We are furthermore interested in the underlying molecular mechanisms related to chronic pain, particularly the involvement of the gut microbiome. Thus, we include omics datasets such as the gut microbiome, metabolites, proteins and genes.
My background is in molecular biology and molecular mechanisms of disease, which I studied in the Netherlands. During my studies, I became fascinated with epidemiology and interdisciplinary research. This led me to persue my PhD at the Unit of cardiovascular and nutritional epidemiology at the Institute of Environmental Medicine (IMM) in Karolinska. My PhD research investigated the impact of a group of environmental pollutants, called perfluoroalkyl substances (PFAS), on cardiovascular disease. We included multi-omics datasets such as genetics, proteins and metabolomics to gain insight in potential underlying mechanisms that linked PFAS exposures to cardiometabolic disturbances. I successfully defended my thesis on the 23rd of March 2024. After my PhD, I continued to work in research as a postdoctoral researcher.
Articles
- Journal article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. 2026;:zwag016Enarsson M; Gustafsson S; Lampa E; Rudholm Feldreich T; Beigrezaei S; Butterworth AS; Elmstahl S; Engstrom G; Hveem K; Johansson M; Lind L; Nilsson PM; Perola M; Schulze MB; Simell B; Sipsma H; Wolford BN; Asvold BO; Assimes TL; Schillemans T; Brooke H; Sundstrom J; Arnlov J
- Article: EUROPEAN JOURNAL OF PAIN. 2025;29(10):e70158Schillemans T; Ronnegard A-S; Assimes TL; Peterson M; Wandell P; Lind L; Arnlov J
- Journal article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2025;54(6):dyaf203Yan Y; Ribbenstedt A; Schillemans T; Brunius C
- Article: ENVIRONMENT INTERNATIONAL. 2025;198:109381Save-Soderbergh M; Gyllenhammar I; Schillemans T; Lindfeldt E; Vogs C; Donat-Vargas C; Ankarberg EH; Glynn A; Ahrens L; Helte E; Akesson A
- Article: ENVIRONMENT INTERNATIONAL. 2025;198:109415Save-Soderbergh M; Gyllenhammar I; Schillemans T; Lindfeldt E; Vogs C; Donat-Vargas C; Helte E; Ankarberg E; Glynn A; Ahrens L; Akesson A
- Journal article: ENVIRONMENT INTERNATIONAL. 2024;190:108931Desalegn A; Schillemans T; Papadopoulou E; Sakhi AK; Haug LS; Henriette Caspersen I; Rodriguez-Carrillo A; Remy S; Schoeters G; Covaci A; Laeremans M; Fernández MF; Pedraza-Diaz S; Kold Jensen T; Frederiksen H; Åkesson A; Cox B; Cynthia D'Cruz S; Rambaud L; Riou M; Kolossa-Gehring M; Gerofke A; Murawski A; Vogel N; Gabriel C; Karakitsios S; Papaioannou N; Sarigiannis D; Barbone F; Rosolen V; Lignell S; Karin Lindroos A; Snoj Tratnik J; Stajnko A; Kosjek T; Tkalec Ž; Fabelova L; Palkovicova Murinova L; Kolena B; Wimmerova S; Szigeti T; Középesy S; van den Brand A; Zock J-P; Janasik B; Wasowicz W; De Decker A; De Henauw S; Govarts E; Iszatt N
- Article: ENVIRONMENT INTERNATIONAL. 2024;190:108931Desalegn A; Schillemans T; Papadopoulou E; Sakhi AK; Haug LS; Caspersen IH; Rodriguez-Carrillo A; Remy S; Schoeters G; Covaci A; Laeremans M; Fernandez MF; Pedraza-Diaz S; Jensen TK; Frederiksen H; Akesson A; Cox B; D'Cruz SC; Rambaud L; Riou M; Kolossa-Gehring M; Gerofke A; Murawski A; Vogel N; Gabriel C; Karakitsios S; Papaioannou N; Sarigiannis D; Barbone F; Rosolen V; Lignell S; Lindroos AK; Tratnik JS; Stajnko A; Kosjek T; Tkalec Z; Fabelova L; Murinova LP; Kolena B; Wimmerova S; Szigeti T; Kozepesy S; van den Brand A; Zock J-P; Janasik B; Wasowicz W; De Decker A; De Henauw S; Govarts E; Iszatt N
- Article: ENVIRONMENT INTERNATIONAL. 2024;187:108727Save-Soderbergh M; Gyllenhammar I; Schillemans T; Lindfeldt E; Vogs C; Donat-Vargas C; Ankarberg EH; Glynn A; Ahrens L; Helte E; Akesson A
- Article: ENVIRONMENTAL SCIENCE & TECHNOLOGY. 2024;58(2):1036-1047Schillemans T; Yan Y; Ribbenstedt A; Donat-Vargas C; Lindh CH; Kiviranta H; Rantakokko P; Wolk A; Landberg R; Akesson A; Brunius C
- Article: BIOINFORMATICS ADVANCES. 2024;4(1):vbae051Yan Y; Schillemans T; Skantze V; Brunius C
- Article: ENVIRONMENTAL POLLUTION. 2023;335:122214Rodriguez-Carrillo A; Remy S; Koppen G; Wauters N; Freire C; Olivas-Martinez A; Schillemans T; Akesson A; Desalegn A; Iszatt N; den Hond E; Verheyen V; Fabelova L; Murinova LP; Pedraza-Diaz S; Castana A; Garcia-Lario JV; Cox B; Govarts E; Baken K; Tena-Sempere M; Olea N; Schoeters G; Fernandez MF
- Article: JAMA NETWORK OPEN. 2023;6(9):e2333347Donat-Vargas C; Schillemans T; Kiviranta H; Rantakokko P; de Faire U; Arrebola JP; Wolk A; Leander K; Akesson A
- Article: TOXICS. 2023;11(8):711Cox B; Wauters N; Rodriguez-Carrillo A; Portengen L; Gerofke A; Kolossa-Gehring M; Lignell S; Lindroos AK; Fabelova L; Murinova LP; Desalegn A; Iszatt N; Schillemans T; Akesson A; Colles A; Den Hond E; Koppen G; Van Larebeke N; Schoeters G; Govarts E; Remy S
- Article: BRITISH JOURNAL OF HAEMATOLOGY. 2023;201(4):783-792Yuan S; Titova OE; Zhang K; Gou W; Schillemans T; Natarajan P; Chen J; Li X; Akesson A; Bruzelius M; Klarin D; Damrauer SM; Larsson SC
- Article: ENVIRONMENTAL POLLUTION. 2023;316(Pt 1):120566Schillemans T; Iszatt N; Remy S; Schoeters G; Fernandez MF; D'Cruz SC; Desalegn A; Haug LS; Lignell S; Lindroos AK; Fabelova L; Murinova LP; Kosjek T; Tkalec Z; Gabriel C; Sarigiannis D; Pedraza-Diaz S; Esteban-Lopez M; Castano A; Rambaud L; Riou M; Pauwels S; Vanlarebeke N; Kolossa-Gehring M; Vogel N; Uhl M; Govarts E; Akesson A
- Article: ENVIRONMENTAL RESEARCH. 2023;216(Pt 2):114570Schillemans T; Bergdahl IA; Hanhineva K; Shi L; Donat-Vargas C; Koponen J; Kiviranta H; Landberg R; akesson A; Brunius C
- Article: FRONTIERS IN PHYSIOLOGY. 2022;13:909870Schillemans T; Tragante V; Maitusong B; Gigante B; Cresci S; Laguzzi F; Vikstrom M; Richards M; Pilbrow A; Cameron V; Foco L; Doughty RN; Kuukasjarvi P; Allayee H; Hartiala JA; Tang WHW; Lyytikainen L-P; Nikus K; Laurikka JO; Srinivasan S; Mordi IR; Trompet S; Kraaijeveld A; van Setten J; Gijsberts CM; Maitland-van der Zee AH; Saely CH; Gong Y; Johnson JA; Cooper-DeHoff RM; Pepine CJ; Casu G; Leiherer A; Drexel H; Horne BD; van der Laan SW; Marziliano N; Hazen SL; Sinisalo J; Kahonen M; Lehtimaki T; Lang CC; Burkhardt R; Scholz M; Jukema JW; Eriksson N; Akerblom A; James S; Held C; Hagstrom E; Spertus JA; Algra A; de Faire U; Akesson A; Asselbergs FW; Patel RS; Leander K
- Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2022;130(3):37007Schillemans T; Donat-Vargas C; Lindh CH; de Faire U; Wolk A; Leander K; Akesson A
- Journal article: ISEE CONFERENCE ABSTRACTS. 2021;2021(1)Schillemans T; Donat Vargas C; Lindh CH; De Faire U; Wolk A; Leander K; Åkesson A
- Journal article: ISEE CONFERENCE ABSTRACTS. 2021;2021(1)Donat Vargas C; Donat Vargas C; Donat Vargas C; Schillemans T; Kiviranta H; De Faire UU; Wolk A; Arrebola P; Arrebola P; Leander K; Åkesson A
- Article: ENVIRONMENT INTERNATIONAL. 2021;146:106180Schillemans T; Shi L; Donat-Vargas C; Hanhineva K; Tornevi A; Johansson I; Koponen J; Kiviranta H; Rolandsson O; Bergdahl IA; Landberg R; Akesson A; Brunius C
- Journal article: ISEE CONFERENCE ABSTRACTS. 2020;2020(1)Schillemans T; Shi L; Donat-Vargas C; Tornevi A; Sommar J; Johansson I; Koponen J; Kiviranta H; Hanhineva K; Rolandsson O; Bergdahl I; Landberg R; Åkesson A; Brunius C
- Journal article: ISEE CONFERENCE ABSTRACTS. 2020;2020(1)Schillemans T; Åkesson A; Mengelers M; Luijten M
- Article: METABOLITES. 2019;9(7):E133-133Schillemans T; Shi L; Liu X; Akesson A; Landberg R; Brunius C
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All other publications
- Review: ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY. 2026;66(1):305-323Schillemans T; van den Brand AD; Åkesson A; Mengelers MJB; Luijten M
- Review: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2024;134(1):141-152Schillemans T; Donat-Vargas C; Akesson A
- Doctoral thesis: 2023Schillemans T
- Conference publication: TOXICOLOGY LETTERS. 2022;368:S67Westerhout J; Krishnan S; Schillemans T; Akesson A; Kramer N; Louisse J; Legler J; Princen H; Stierum R
- Preprint: SSRN ELECTRONIC JOURNAL.Rodríguez-Carrillo A; Remy S; Koppen G; Wauters N; Freire C; Olivas-Martínez A; Schillemans T; Akesson A; Desalegn A; Iszatt N; Hond ED; Verheyen VJ; Fábelová L; Murinova LP; Díaz SP; Castano A; García-Lario JV; Cox B; Govarts E; Baken K; Tena-Sempere M; Olea N; Schoeters G; Fernández MF
Grants
- Associations of fibromyalgia with cardiovascular disease and dementiaStiftelsen för ålderssjukdomar vid KI 202531 October 2025 - 31 October 2026Chronic pain impacts half of the older population and is a major cause of disability. Fibromyalgia is one diagnosis for chronic pain characterized by widespread pain, fatigue and insomnia without underlying cause. Current research shows implications of fibromyalgia as a risk factor for degenerative diseases such as cardiovascular disease and dementia. Additionally, pain medication is often used to manage symptoms, although with limited evidence for effectiveness, which could increase the risk of side effects and adverse events. Current clinical guidelines do not include fibromyalgia as a risk factor due to limited evidence. Thus, in this project, we will use a large register-based cohort to investigate associations between fibromyalgia and cardiovascular disease and dementia. Additionally, we aim to investigate whether certain types of pain medication mediate the association.
Employments
- Postdoctoral Researcher, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2024-2026
- Postdoctoral Researcher, Institute of Environmental Medicine, Karolinska Institutet, 2023-2024
Degrees and Education
- Degree Of Doctor Of Philosophy, Institute of Environmental Medicine, Karolinska Institutet, 2023
- Msc, Molecular Mechanisms of Disease, Radboud University Nijmegen, 2018
- Bsc, Biology, Leiden University, 2015
