Sofia Ernestam

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Articles

Article: ARTHRITIS RESEARCH & THERAPY. 2022;24(1):203
Neither low social support nor low decision latitude at work is associated with disease remission among patients with rheumatoid arthritis: results from the Swedish EIRA study
Hedenstierna L; Hedstrom AK; Klareskog L; Di Giuseppe D; Alfredsson L; Askling J; Ernestam S; Saevarsdottir S; Ljung L
Article: ARTHRITIS CARE & RESEARCH. 2021;73(9):1312-1321
Pain Over Two Years After Start of Biologic Versus Conventional Combination Treatment in Early Rheumatoid Arthritis: Results From a Swedish Randomized Controlled Trial
Olofsson T; Wallman JK; Joud A; Schelin MEC; Ernestam S; van Vollenhoven R; Saevarsdottir S; Lampa J
Article: RHEUMATOLOGY. 2021;60(5):2217-2222
Mortality over 14 years in MTX-refractory patients randomized to a strategy of addition of infliximab or sulfasalazine and hydroxychloroquine
Miller H; Wallman JK; Petersson IF; Saevarsdottir S; Soderlng J; Ernestam S; Askling J; van Vollenhoven R; Neovius M
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2021;50(3):178-182
Social stressors and risk of rheumatoid arthritis and their relationship to known modifiable risk factors: results from the Swedish EIRA study
Hedenstierna L; Opava CH; Askling J; Jiang X; Ernestam S; Alfredsson L; Klareskog L; Saevarsdottir S
Article: ARTHRITIS CARE & RESEARCH. 2019;71(12):1556-1565
International Consortium for Health Outcome Measurement Set of Outcomes That Matter to People Living With Inflammatory Arthritis: Consensus From an International Working Group
Oude Voshaar MAH; Das Gupta Z; Bijlsma JWJ; Boonen A; Chau J; Courvoisier DS; Curtis JR; Ellis B; Ernestam S; Gossec L; Hale C; Hornjeff J; Leung KYY; Lidar M; Mease P; Michaud K; Mody GM; Ndosi M; Opava CH; Pinheiro GRC; Salt M; Soriano ER; Taylor WJ; Voshaar MJH; Weel AEAM; de Wit M; Wulffraat N; van de Laar MAFJ; Vonkeman HE
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2019;48(5):362-366
Association of female sex and positive rheumatoid factor with low serum infliximab and anti-drug antibodies, related to treatment failure in early rheumatoid arthritis: results from the SWEFOT trial population
Hambardzumyan K; Hermanrud C; Marits P; Vivar N; Ernestam S; Wallman JK; van Vollenhoven RF; Fogdell-Hahn A; Saevarsdottir S
Article: RHEUMATOLOGY. 2019;58(2):227-236
Prevalence of sustained remission in rheumatoid arthritis: impact of criteria sets and disease duration, a Nationwide Study in Sweden
Einarsson JT; Willim M; Ernestam S; Saxne T; Geborek P; Kapetanovic MC
Article: RHEUMATOLOGY. 2019;58(8):1367-1377
Comparative effectiveness of abatacept, rituximab, tocilizumab and TNFi biologics in RA: results from the nationwide Swedish register
Frisell T; Dehlin M; Di Giuseppe D; Feltelius N; Turesson C; Askling J; Ernestam S; Klareskog L; Nisell R; Baecklund E; Kastbom A; Jacobsson L; Lindqvist E; d'Elia HF; Rantapaa-Dahlqvist S
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2018;47(6):465-474
Biological treatment in ankylosing spondylitis in the Nordic countries during 2010-2016: a collaboration between five biological registries
Glintborg B; Lindstrom U; Aaltonen K; Kristianslund EK; Gudbjornsson B; Chatzidionysiou K; Askling J; Nordstrom D; Hetland ML; Di Giuseppe D; Dreyer L; Kristensen LE; Jorgensen TS; Eklund K; Grondal G; Ernestam S; Joensuu J; Tormanen MRK; Skydsgaard H; Hagfors J; Kvien TK; Lie E; Fagerli K; Geirsson AJ; Jonsson H; Provan SA; Krogh NS; Jacobsson LTH
Article: ARTHRITIS CARE & RESEARCH. 2018;70(10):1563-1567
Tuberculosis Risk in Ankylosing Spondylitis, Other Spondyloarthritis, and Psoriatic Arthritis in Sweden: A Population-Based Cohort Study
de Vries MK; Arkema EV; Jonsson J; Bruchfeld J; Jacobsson LTH; Askling J
Article: ANNALS OF INTERNAL MEDICINE. 2018;169(5):291-299
Tumor Necrosis Factor Inhibitors and Cancer Recurrence in Swedish Patients With Rheumatoid Arthritis A Nationwide Population-Based Cohort Study
Raaschou P; Soderling J; Turesson C; Askling J
Article: EXPERT OPINION ON BIOLOGICAL THERAPY. 2018;18(5):499-504
Uptake of rheumatology biosimilars in the absence of forced switching
Di Giuseppe D; Frisell T; Ernestam S; Forsblad-D'Elia H; Lindqvist E; Lindstrom U; Sjowall C; Askling J
Article: ARTHRITIS & RHEUMATOLOGY. 2017;69(5):953-963
A Multi-Biomarker Disease Activity Score and the Choice of Second-Line Therapy in Early Rheumatoid Arthritis After Methotrexate Failure
Hambardzumyan K; Saevarsdottir S; Forslind K; Petersson IF; Wallman JK; Ernestam S; Bolce RJ; van Vollenhoven RF
Article: ARTHRITIS CARE & RESEARCH. 2016;68(12):1758-1766
Infliximab Versus Conventional Combination Treatment and Seven-Year Work Loss in Early Rheumatoid Arthritis: Results of a Randomized Swedish Trial
Eriksson JK; Wallman JK; Miller H; Petersson IF; Ernestam S; Vivar N; van Vollenhoven RF; Neovius M
Article: QUALITY MANAGEMENT IN HEALTH CARE. 2016;25(4):203-212
Value-Based Health Care for Chronic Care: Aligning Outcomes Measurement with the Patient Perspective
Ebbevi D; Forsberg HH; Essen A; Ernestam S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(7):1272-1278
Do RA or TNF inhibitors increase the risk of cervical neoplasia or of recurrence of previous neoplasia? A nationwide study from Sweden
Wadstrom H; Frisell T; Sparen P; Askling J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(2):356-361
Changes in the anticitrullinated peptide antibody response in relation to therapeutic outcome in early rheumatoid arthritis: results from the SWEFOT trial
Kastbom A; Forslind K; Ernestam S; Geborek P; Karlsson JA; Petersson IF; Saevarsdottir S; Klareskog L; van Vollenhoven RF; Lundberg K
Article: RMD OPEN. 2016;2(1):e000184
Patient-initiated appointments compared with standard outpatient care for rheumatoid arthritis: a randomised controlled trial
Fredriksson C; Ebbevi D; Waldheim E; Lindblad S; Ernestam S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(8):1509-1514
Current smoking status is a strong predictor of radiographic progression in early rheumatoid arthritis: results from the SWEFOT trial
Saevarsdottir S; Rezaei H; Geborek P; Petersson I; Ernestam S; Albertsson K; Forslind K; van Vollenhoven RF
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(6):1094-1101
Cost-effectiveness of infliximab versus conventional combination treatment in methotrexate-refractory early rheumatoid arthritis: 2-year results of the register-enriched randomised controlled SWEFOT trial
Eriksson JK; Karlsson JA; Bratt J; Petersson IF; van Vollenhoven RF; Ernestam S; Geborek P; Neovius M
Article: ANNALS OF THE RHEUMATIC DISEASES. 2013;72(12):1927-1933
Addition of infliximab compared with addition of sulfasalazine and hydroxychloroquine to methotrexate in early rheumatoid arthritis: 2-year quality-of-life results of the randomised, controlled, SWEFOT trial
Karlsson JA; Neovius M; Nilsson J-A; Petersson IF; Bratt J; van Vollenhoven RF; Ernestam S; Geborek P
Article: JAMA INTERNAL MEDICINE. 2013;173(15):1407-1414
Biological vs Conventional Combination Treatment and Work Loss in Early Rheumatoid Arthritis A Randomized Trial
Eriksson JK; Neovius M; Bratt J; Petersson IF; van Vollenhoven RF; Geborek P; Ernestam S
Article: ARTHRITIS CARE & RESEARCH. 2013;65(6):870-878
Incidence of Rheumatoid Arthritis in Sweden: A Nationwide Population-Based Assessment of Incidence, Its Determinants, and Treatment Penetration
Eriksson JK; Neovius M; Ernestam S; Lindblad S; Simard JF; Askling J
Article: LAKARTIDNINGEN. 2012;109(47):2159-2161
[Value-based health care--strategy for efficient Swedish health care. Care should be organized based on what gives value to the patient].
Höglund PJ; Essén A; Choi S; Ernestam S; Kaarme J; Neovius M
Article: LANCET. 2012;379(9827):1712-1720
Conventional combination treatment versus biological treatment in methotrexate-refractory early rheumatoid arthritis: 2 year follow-up of the randomised, non-blinded, parallel-group Swefot trial
van Vollenhoven RF; Geborek P; Forslind K; Albertsson K; Ernestam S; Petersson IF; Chatzidionysiou K; Bratt J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2012;71(2):186-191
In early rheumatoid arthritis, patients with a good initial response to methotrexate have excellent 2-year clinical outcomes, but radiological progression is not fully prevented: data from the methotrexate responders population in the SWEFOT trial
Rezaei H; Saevarsdottir S; Forslind K; Albertsson K; Wallin H; Bratt J; Ernestam S; Geborek P; Petersson IF; van Vollenhoven RF
Article: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(3):469-475
Predictors of response to methotrexate in early DMARD naive rheumatoid arthritis: results from the initial open-label phase of the SWEFOT trial
Saevarsdottir S; Wallin H; Seddighzadeh M; Ernestam SA; Geborek P; Petersson IF; Bratt J; van Vollenhoven RF
Article: LANCET. 2009;374(9688):459-466
Addition of infliximab compared with addition of sulfasalazine and hydroxychloroquine to methotrexate in patients with early rheumatoid arthritis (Swefot trial): 1-year results of a randomised trial
van Vollenhoven RF; Ernestam S; Geborek P; Petersson IF; Coster L; Waltbrand E; Zickert A; Theander J; Thorner A; Hellstrom H; Teleman A; Dackhammar C; Akre F; Forslind K; Ljung L; Oding R; Chatzidionysiou A; Wornert M; Bratt J
Article: ARTHRITIS RESEARCH & THERAPY. 2008;10(2):R33
Systemic TNF blockade does not modulate synovial expression of the pro-inflammatory mediator HMGB1 in rheumatoid arthritis patients - a prospective clinical study
Sundberg E; Grundtman C; Klint EAF; Lindberg J; Ernestam S; Ulfgren A-K; Harris HE; Andersson U
Article: ANNALS OF THE RHEUMATIC DISEASES. 2007;66(11):1462-1466
Low-dose glucocorticoid therapy decreases risk for treatment-limiting infusion reaction to infliximab in patients with rheumatoid arthritis
Augustsson J; Eksborg S; Ernestam S; Gullstrom E; van Vollenhoven R
Article: JOURNAL OF RHEUMATOLOGY. 2007;34(7):1451-1458
Increased DHEAS levels in patients with rheumatoid arthritis after treatment with tumor necrosis factor antagonists:: Evidence for improved adrenal function
Ernestam S; Hafstrom I; Werner S; Carlstrom K; Tengstrand B
Article: ARTHRITIS & RHEUMATOLOGY. 2007;56(2):448-452
Fcγ receptor type IIIA genotype and response to tumor necrosis factor α-blocking agents in patients with rheumatoid arthritis
Kastbom A; Bratt J; Ernestam S; Lampa J; Padyukov L; Soderkvist P; Skogh T
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2006;35(3):182-188
Interleukin-1β influences the effect of infliximab on temporomandibular joint pain in rheumatoid arthritis
Kopp S; Alstergren P; Ernestam S; Nordahl S; Bratt J
Article: ARTHRITIS RESEARCH & THERAPY. 2006;8(1):R18
Synovial expression of IL-15 in rheumatoid arthritis is not influenced by blockade of tumour necrosis factor
Ernestam S; Klint EA; Catrina AI; Sundberg E; Engström M; Klareskog L; Ulfgren K
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(1):76-81
Anti-tumor necrosis factor therapy increases synovial osteoprotegerin expression in rheumatoid arthritis
Catrina AI; af Klint E; Ernestam S; Catrina SB; Makrygiannakis D; Botusan IR; Klareskog L; Ulfgren AK
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2005;34(5):353-358
Adalimumab (Humira®) restores clinical response in patients with secondary loss of efficacy from infliximab (Remicade®) or etanercept (Enbrel®): results from the STURE registry at Karolinska University Hospital
Wick MC; Ernestam S; Lindblad S; Bratt J; Klareskog L; van Vollenhoven RF
Article: LAKARTIDNINGEN. 2005;102(49):3788-3793
[TNF blockade in rheumatoid arthritis can cause severe fibrosing alveolitis. Six case reports].
Tengstrand B; Ernestam S; Engvall I-L; Rydvald Y; Hafström I
Article: JOURNAL OF RHEUMATOLOGY. 2003;30(8):1748-1755
Evidence for immunostimulatory effects of intramuscular gold in patients with rheumatoid arthritis: Correlation with skin reactions
Ernestam S; Lampa J; Rogberg S; Rönnelid J; Klareskog L; Hafström I
Article: ANNALS OF THE RHEUMATIC DISEASES. 2003;62(6):526-529
Genetic markers for the efficacy of tumour necrosis factor blocking therapy in rheumatoid arthritis
Padyukov L; Lampa J; Heimbürger M; Ernestam S; Cederholm T; Lundkvist I; Andersson P; Hermansson Y; Harju A; Klareskog L; Bratt J
Article: ARTHRITIS RESEARCH & THERAPY. 2003;5(6):R347-R351
Etanercept versus etanercept plus methotrexate: a registry-based study suggesting that the combination is clinically more efficacious
van Vollenhoven RF; Ernestam S; Harju A; Bratt J; Klareskog L
Article: RHEUMATOLOGY. 2002;41(5):484-489
Anti-tumour necrosis factor (TNF)-α therapy (etanercept) down-regulates serum matrix metalloproteinase (MMP)-3 and MMP-1 in rheumatoid arthritis
Catrina AI; Lampa J; Ernestam S; af Klint E; Bratt J; Klareskog L; Ulfgren AK
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Corrigendum: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2019;48(3):258
Comparing patient-reported outcomes entered at home versus at hospital, and testing touch screens for initial recruitment to scientific trials in arthritis patients (vol 48, pg 178, 2019)
Glintborg B; Lindstrom U; Aaltonen K; Kristianslund E; Gudbjornsson B; Chatzidionysiou K; Askling J; Nordstrom D; Hetland M; Di Giuseppe D; Dreyer L; Kristensen LE; Jorgensen TS; Eklund K; Grondal G; Ernestam S; Joensuu J; Tormanen MEK; Skydsgaard H; Hagfors J; Kvien TK; Lie E; Fagerli K; Geirsson AJ; Jonsson H; Provan SA; Krogh NS; Jacobsson LTH
Review: QJM-AN INTERNATIONAL JOURNAL OF MEDICINE. 2017;110(3):125-129
Creating a culture of health: evolving healthcare systems and patient engagement
Lindblad S; Ernestam S; Van Citters AD; Lind C; Morgan TS; Nelson EC
Other: LAKARTIDNINGEN. 2009;106(12):871
[Future care requires future ways of working].
Ahlberg A; Berner J; Ernestam S; Hallén K; Hägglund H; Liljegren A; Löfberg E; Martling C-R; Sarkar N; Wickström R
Doctoral thesis: 2006
Rheumatoid arthritis : pharmacological modulation of cytokines : aspects of clinical response and endocrine regulation
Ernestam S
Published conference paper: CELLS TISSUES ORGANS. 2005;180(1):22-30
Reduction of temporomandibular joint pain after treatment with a combination of methotrexate and infliximab is associated with changes in synovial fluid and plasma cytokines in rheumatoid arthritis
Kopp S; Alstergren P; Ernestam S; Nordahl S; Morin P; Bratt J

Employments

Affiliated to Research, Department of Medicine, Karolinska Institutet, 2023-2026

Degrees and Education

Doctor Of Philosophy, Department of Medicine, Huddinge, Karolinska Institutet, 2006
University Medical Degree, Karolinska Institutet, 1993

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