Sofia Ernestam

Publications
CV
Public outreach and news

Articles

Article: ARTHRITIS RESEARCH & THERAPY. 2022;24(1):203
Neither low social support nor low decision latitude at work is associated with disease remission among patients with rheumatoid arthritis: results from the Swedish EIRA study
Hedenstierna L; Hedstrom AK; Klareskog L; Di Giuseppe D; Alfredsson L; Askling J; Ernestam S; Saevarsdottir S; Ljung L
Article: ARTHRITIS CARE AND RESEARCH. 2021;73(9):1312-1321
Pain Over Two Years After Start of Biologic Versus Conventional Combination Treatment in Early Rheumatoid Arthritis: Results From a Swedish Randomized Controlled Trial
Olofsson T; Wallman JK; Joud A; Schelin MEC; Ernestam S; van Vollenhoven R; Saevarsdottir S; Lampa J
Article: RHEUMATOLOGY. 2021;60(5):2217-2222
Mortality over 14 years in MTX-refractory patients randomized to a strategy of addition of infliximab or sulfasalazine and hydroxychloroquine
Miller H; Wallman JK; Petersson IF; Saevarsdottir S; Soderlng J; Ernestam S; Askling J; van Vollenhoven R; Neovius M
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2021;50(3):178-182
Social stressors and risk of rheumatoid arthritis and their relationship to known modifiable risk factors: results from the Swedish EIRA study
Hedenstierna L; Opava CH; Askling J; Jiang X; Ernestam S; Alfredsson L; Klareskog L; Saevarsdottir S
Article: ARTHRITIS CARE AND RESEARCH. 2019;71(12):1556-1565
International Consortium for Health Outcome Measurement Set of Outcomes That Matter to People Living With Inflammatory Arthritis: Consensus From an International Working Group
Oude Voshaar MAH; Das Gupta Z; Bijlsma JWJ; Boonen A; Chau J; Courvoisier DS; Curtis JR; Ellis B; Ernestam S; Gossec L; Hale C; Hornjeff J; Leung KYY; Lidar M; Mease P; Michaud K; Mody GM; Ndosi M; Opava CH; Pinheiro GRC; Salt M; Soriano ER; Taylor WJ; Voshaar MJH; Weel AEAM; de Wit M; Wulffraat N; van de Laar MAFJ; Vonkeman HE
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2019;48(5):362-366
Association of female sex and positive rheumatoid factor with low serum infliximab and anti-drug antibodies, related to treatment failure in early rheumatoid arthritis: results from the SWEFOT trial population
Hambardzumyan K; Hermanrud C; Marits P; Vivar N; Ernestam S; Wallman JK; van Vollenhoven RF; Fogdell-Hahn A; Saevarsdottir S
Article: RHEUMATOLOGY. 2019;58(2):227-236
Prevalence of sustained remission in rheumatoid arthritis: impact of criteria sets and disease duration, a Nationwide Study in Sweden
Einarsson JT; Willim M; Ernestam S; Saxne T; Geborek P; Kapetanovic MC
Article: RHEUMATOLOGY. 2019;58(8):1367-1377
Comparative effectiveness of abatacept, rituximab, tocilizumab and TNFi biologics in RA: results from the nationwide Swedish register
Frisell T; Dehlin M; Di Giuseppe D; Feltelius N; Turesson C; Askling J; Ernestam S; Klareskog L; Nisell R; Baecklund E; Kastbom A; Jacobsson L; Lindqvist E; d'Elia HF; Rantapaa-Dahlqvist S
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2018;47(6):465-474
Biological treatment in ankylosing spondylitis in the Nordic countries during 2010-2016: a collaboration between five biological registries
Glintborg B; Lindstrom U; Aaltonen K; Kristianslund EK; Gudbjornsson B; Chatzidionysiou K; Askling J; Nordstrom D; Hetland ML; Di Giuseppe D; Dreyer L; Kristensen LE; Jorgensen TS; Eklund K; Grondal G; Ernestam S; Joensuu J; Tormanen MRK; Skydsgaard H; Hagfors J; Kvien TK; Lie E; Fagerli K; Geirsson AJ; Jonsson H; Provan SA; Krogh NS; Jacobsson LTH
Article: ARTHRITIS CARE AND RESEARCH. 2018;70(10):1563-1567
Tuberculosis Risk in Ankylosing Spondylitis, Other Spondyloarthritis, and Psoriatic Arthritis in Sweden: A Population-Based Cohort Study
de Vries MK; Arkema EV; Jonsson J; Bruchfeld J; Jacobsson LTH; Askling J
Article: ANNALS OF INTERNAL MEDICINE. 2018;169(5):291-299
Tumor Necrosis Factor Inhibitors and Cancer Recurrence in Swedish Patients With Rheumatoid Arthritis A Nationwide Population-Based Cohort Study
Raaschou P; Soderling J; Turesson C; Askling J
Article: EXPERT OPINION ON BIOLOGICAL THERAPY. 2018;18(5):499-504
Uptake of rheumatology biosimilars in the absence of forced switching
Di Giuseppe D; Frisell T; Ernestam S; Forsblad-D'Elia H; Lindqvist E; Lindstrom U; Sjowall C; Askling J
Article: ARTHRITIS & RHEUMATOLOGY. 2017;69(5):953-963
A Multi-Biomarker Disease Activity Score and the Choice of Second-Line Therapy in Early Rheumatoid Arthritis After Methotrexate Failure
Hambardzumyan K; Saevarsdottir S; Forslind K; Petersson IF; Wallman JK; Ernestam S; Bolce RJ; van Vollenhoven RF
Article: ARTHRITIS CARE AND RESEARCH. 2016;68(12):1758-1766
Infliximab Versus Conventional Combination Treatment and Seven-Year Work Loss in Early Rheumatoid Arthritis: Results of a Randomized Swedish Trial
Eriksson JK; Wallman JK; Miller H; Petersson IF; Ernestam S; Vivar N; van Vollenhoven RF; Neovius M
Article: QUALITY MANAGEMENT IN HEALTH CARE. 2016;25(4):203-212
Value-Based Health Care for Chronic Care: Aligning Outcomes Measurement with the Patient Perspective
Ebbevi D; Forsberg HH; Essen A; Ernestam S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(7):1272-1278
Do RA or TNF inhibitors increase the risk of cervical neoplasia or of recurrence of previous neoplasia? A nationwide study from Sweden
Wadstrom H; Frisell T; Sparen P; Askling J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(2):356-361
Changes in the anticitrullinated peptide antibody response in relation to therapeutic outcome in early rheumatoid arthritis: results from the SWEFOT trial
Kastbom A; Forslind K; Ernestam S; Geborek P; Karlsson JA; Petersson IF; Saevarsdottir S; Klareskog L; van Vollenhoven RF; Lundberg K
Article: RMD OPEN. 2016;2(1):e000184
Patient-initiated appointments compared with standard outpatient care for rheumatoid arthritis: a randomised controlled trial.
Fredriksson C; Ebbevi D; Waldheim E; Lindblad S; Ernestam S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(8):1509-1514
Current smoking status is a strong predictor of radiographic progression in early rheumatoid arthritis: results from the SWEFOT trial
Saevarsdottir S; Rezaei H; Geborek P; Petersson I; Ernestam S; Albertsson K; Forslind K; van Vollenhoven RF
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(6):1094-1101
Cost-effectiveness of infliximab versus conventional combination treatment in methotrexate-refractory early rheumatoid arthritis: 2-year results of the register-enriched randomised controlled SWEFOT trial
Eriksson JK; Karlsson JA; Bratt J; Petersson IF; van Vollenhoven RF; Ernestam S; Geborek P; Neovius M
Article: ANNALS OF THE RHEUMATIC DISEASES. 2013;72(12):1927-1933
Addition of infliximab compared with addition of sulfasalazine and hydroxychloroquine to methotrexate in early rheumatoid arthritis: 2-year quality-of-life results of the randomised, controlled, SWEFOT trial
Karlsson JA; Neovius M; Nilsson J-A; Petersson IF; Bratt J; van Vollenhoven RF; Ernestam S; Geborek P
Article: JAMA INTERNAL MEDICINE. 2013;173(15):1407-1414
Biological vs Conventional Combination Treatment and Work Loss in Early Rheumatoid Arthritis A Randomized Trial
Eriksson JK; Neovius M; Bratt J; Petersson IF; van Vollenhoven RF; Geborek P; Ernestam S
Article: ARTHRITIS CARE AND RESEARCH. 2013;65(6):870-878
Incidence of Rheumatoid Arthritis in Sweden: A Nationwide Population-Based Assessment of Incidence, Its Determinants, and Treatment Penetration
Eriksson JK; Neovius M; Ernestam S; Lindblad S; Simard JF; Askling J
Article: LAKARTIDNINGEN. 2012;109(47):2159-2161
[Value-based health care--strategy for efficient Swedish health care. Care should be organized based on what gives value to the patient].
Höglund PJ; Essén A; Choi S; Ernestam S; Kaarme J; Neovius M
Article: THE LANCET. 2012;379(9827):1712-1720
Conventional combination treatment versus biological treatment in methotrexate-refractory early rheumatoid arthritis: 2 year follow-up of the randomised, non-blinded, parallel-group Swefot trial
van Vollenhoven RF; Geborek P; Forslind K; Albertsson K; Ernestam S; Petersson IF; Chatzidionysiou K; Bratt J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2012;71(2):186-191
In early rheumatoid arthritis, patients with a good initial response to methotrexate have excellent 2-year clinical outcomes, but radiological progression is not fully prevented: data from the methotrexate responders population in the SWEFOT trial
Rezaei H; Saevarsdottir S; Forslind K; Albertsson K; Wallin H; Bratt J; Ernestam S; Geborek P; Petersson IF; van Vollenhoven RF
Article: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(3):469-475
Predictors of response to methotrexate in early DMARD naive rheumatoid arthritis: results from the initial open-label phase of the SWEFOT trial
Saevarsdottir S; Wallin H; Seddighzadeh M; Ernestam SA; Geborek P; Petersson IF; Bratt J; van Vollenhoven RF
Article: THE LANCET. 2009;374(9688):459-466
Addition of infliximab compared with addition of sulfasalazine and hydroxychloroquine to methotrexate in patients with early rheumatoid arthritis (Swefot trial): 1-year results of a randomised trial
van Vollenhoven RF; Ernestam S; Geborek P; Petersson IF; Coster L; Waltbrand E; Zickert A; Theander J; Thorner A; Hellstrom H; Teleman A; Dackhammar C; Akre F; Forslind K; Ljung L; Oding R; Chatzidionysiou A; Wornert M; Bratt J
Article: ARTHRITIS RESEARCH & THERAPY. 2008;10(2):R33
Systemic TNF blockade does not modulate synovial expression of the pro-inflammatory mediator HMGB1 in rheumatoid arthritis patients - a prospective clinical study
Sundberg E; Grundtman C; Klint EAF; Lindberg J; Ernestam S; Ulfgren A-K; Harris HE; Andersson U
Article: ANNALS OF THE RHEUMATIC DISEASES. 2007;66(11):1462-1466
Low-dose glucocorticoid therapy decreases risk for treatment-limiting infusion reaction to infliximab in patients with rheumatoid arthritis
Augustsson J; Eksborg S; Ernestam S; Gullstrom E; van Vollenhoven R
Article: JOURNAL OF RHEUMATOLOGY. 2007;34(7):1451-1458
Increased DHEAS levels in patients with rheumatoid arthritis after treatment with tumor necrosis factor antagonists:: Evidence for improved adrenal function
Ernestam S; Hafstrom I; Werner S; Carlstrom K; Tengstrand B
Article: ARTHRITIS & RHEUMATOLOGY. 2007;56(2):448-452
Fcγ receptor type IIIA genotype and response to tumor necrosis factor α-blocking agents in patients with rheumatoid arthritis
Kastbom A; Bratt J; Ernestam S; Lampa J; Padyukov L; Soderkvist P; Skogh T
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2006;35(3):182-188
Interleukin-1β influences the effect of infliximab on temporomandibular joint pain in rheumatoid arthritis
Kopp S; Alstergren P; Ernestam S; Nordahl S; Bratt J
Article: ARTHRITIS RESEARCH & THERAPY. 2006;8(1):R18
Synovial expression of IL-15 in rheumatoid arthritis is not influenced by blockade of tumour necrosis factor
Ernestam S; Klint EA; Catrina AI; Sundberg E; Engström M; Klareskog L; Ulfgren K
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(1):76-81
Anti-tumor necrosis factor therapy increases synovial osteoprotegerin expression in rheumatoid arthritis
Catrina AI; af Klint E; Ernestam S; Catrina SB; Makrygiannakis D; Botusan IR; Klareskog L; Ulfgren AK
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2005;34(5):353-358
Adalimumab (Humira®) restores clinical response in patients with secondary loss of efficacy from infliximab (Remicade®) or etanercept (Enbrel®):: results from the STURE registry at Karolinska University Hospital
Wick MC; Ernestam S; Lindblad S; Bratt J; Klareskog L; van Vollenhoven RF
Article: LAKARTIDNINGEN. 2005;102(49):3788-3793
[TNF blockade in rheumatoid arthritis can cause severe fibrosing alveolitis. Six case reports].
Tengstrand B; Ernestam S; Engvall I-L; Rydvald Y; Hafström I
Article: JOURNAL OF RHEUMATOLOGY. 2003;30(8):1748-1755
Evidence for immunostimulatory effects of intramuscular gold in patients with rheumatoid arthritis:: Correlation with skin reactions
Ernestam S; Lampa J; Rogberg S; Rönnelid J; Klareskog L; Hafström I
Article: ANNALS OF THE RHEUMATIC DISEASES. 2003;62(6):526-529
Genetic markers for the efficacy of tumour necrosis factor blocking therapy in rheumatoid arthritis
Padyukov L; Lampa J; Heimbürger M; Ernestam S; Cederholm T; Lundkvist I; Andersson P; Hermansson Y; Harju A; Klareskog L; Bratt J
Article: ARTHRITIS RESEARCH & THERAPY. 2003;5(6):R347-R351
Etanercept versus etanercept plus methotrexate: a registry-based study suggesting that the combination is clinically more efficacious
van Vollenhoven RF; Ernestam S; Harju A; Bratt J; Klareskog L
Article: RHEUMATOLOGY. 2002;41(5):484-489
Anti-tumour necrosis factor (TNF)-α therapy (etanercept) down-regulates serum matrix metalloproteinase (MMP)-3 and MMP-1 in rheumatoid arthritis
Catrina AI; Lampa J; Ernestam S; af Klint E; Bratt J; Klareskog L; Ulfgren AK
Show more

All other publications

Corrigendum: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2019;48(3):258
Comparing patient-reported outcomes entered at home versus at hospital, and testing touch screens for initial recruitment to scientific trials in arthritis patients (vol 48, pg 178, 2019)
Glintborg B; Lindstrom U; Aaltonen K; Kristianslund E; Gudbjornsson B; Chatzidionysiou K; Askling J; Nordstrom D; Hetland M; Di Giuseppe D; Dreyer L; Kristensen LE; Jorgensen TS; Eklund K; Grondal G; Ernestam S; Joensuu J; Tormanen MEK; Skydsgaard H; Hagfors J; Kvien TK; Lie E; Fagerli K; Geirsson AJ; Jonsson H; Provan SA; Krogh NS; Jacobsson LTH
Review: QJM - MONTHLY JOURNAL OF THE ASSOCIATION OF PHYSICIANS. 2017;110(3):125-129
Creating a culture of health: evolving healthcare systems and patient engagement
Lindblad S; Ernestam S; Van Citters AD; Lind C; Morgan TS; Nelson EC
Other: LAKARTIDNINGEN. 2009;106(12):871
[Future care requires future ways of working].
Ahlberg A; Berner J; Ernestam S; Hallén K; Hägglund H; Liljegren A; Löfberg E; Martling C-R; Sarkar N; Wickström R
Thesis / dissertation: 2006
Rheumatoid arthritis : pharmacological modulation of cytokines : aspects of clinical response and endocrine regulation
Ernestam, Sofia
Published conference paper: CELLS TISSUES ORGANS. 2005;180(1):22-30
Reduction of temporomandibular joint pain after treatment with a combination of methotrexate and infliximab is associated with changes in synovial fluid and plasma cytokines in rheumatoid arthritis
Kopp S; Alstergren P; Ernestam S; Nordahl S; Morin P; Bratt J

Employments

Affiliated to Research, Department of Medicine, Karolinska Institutet, 2023-2026

Degrees and Education

Doctor Of Philosophy, Department of Medicine, Huddinge, Karolinska Institutet, 2006
University Medical Degree, Karolinska Institutet, 1993

Articles

All other publications

Employments

Degrees and Education

News from KI

Events from KI