Rolf Lewensohn
Professor | Docent
E-mail: rolf.lewensohn@ki.se
Visiting address: BioClinicum vän 6, Visionsgatan 4, 17164 Solna
Postal address: K7 Onkologi-Patologi, K7 Forskning Ekman Lewensohn, 171 77 Stockholm
Part of:
- Department of Oncology-Pathology
- Precision Cancer Medicine in Lung Cancer - Preclinical, Translational & Clinical Research – Simon Ekman's research group
- Precision cancer medicine and precision radiotherapy in lung cancer - from molecular mechanisms/biomarkers to clinical trials – Rolf Lewensohn's team
About me
- Professor of Oncology, Karolinska Institute
- Senior Consultant, Oncology Clinic, Karolinska Hospital.
- Born 1949 - leader of a Research Group with some 20 members at the Karolinska Institute Department of Oncology-Pathology.
- Programme Director, Swedish Radiation Emergency Medicine Centre (KcRN), a radiation emergency function of the Swedish Board of Health and Welfare.
- Member of the Scientific Boards of several Swedish funding bodies.
- Author of more than 110 research papers on cancer.
Research
- Rolf Lewensohn has a scientific background in DNA repair apoptotic signalling in cancer as related to cancer therapy. His research focuses on the sensitivity of human tumours to radiation, as well as conventional and experimental chemotherapeutic drugs, with regard to the role of growth factor-, DNA-repair-, and apoptotic- signalling.
He and his group aim to develop new oncological treatments in the form of novel drug candidates and precision radiotherapy, with a personalized cancer medicine approach. The general interest of the research group is the development of novel treatments (both drugs and radiotherapy), mainly focused on lung cancer and furthermore breast, renal, and cervical cancer, multiple myeloma, and acute myeloid leukemia. From all types of malignancies, lung cancer is the leading cause of cancer-related mortality. Each year approximately 1.4 million people die worldwide because of lung cancer. Possibilities to increase survival of lung cancer patients are rapidly emerging. Early stages of lung cancer in the form of a localized intra-thoracic tumor or a tumor with a limited number of metastases may now be attacked with curative intent. However, lung cancer is often detected only at a late stage. Moreover, after an initial response to treatment, therapy-resistant clones inevitably start growing resulting in rapid disease progression. New knowledge of mutations specifically related to a certain type of cancer, identification of biomarkers to predict therapy response, and understanding of the molecular mechanisms of action of novel drugs opens up for personalization of treatment.
A number of novel drug candidates, among which some are reacting with tumor DNA and/or directed to interfering with DNA repair, are being developed in the group's laboratory through a full preclinical test system preceding clinical trials. This includes analysis of biochemical mechanisms of action of these drugs and identification of corresponding putative biomarkers to create precision in selecting patients with sensitive tumors for a specific treatment, while patients with resistant disease can be deselected from unnecessary treatment causing only side effects. Part of the research is discovery, using a systems biology approach including genomic and proteomic methodologies, focusing on cell signaling pathways and DNA damage/repair. The research comprises of work on tumor cells lines, primary tumor material from the Karolinska Biobank and in vivo experiments to determine proof-of-principal and pharmacological parameters. The group has brought one compound Melflufen, which is a conjugate of a peptide and a DNA-alkylator, to a phase II clinical trial with multiple myeloma patients.
In parallel, the group runs clinical trials on lung cancer at the Karolinska university hospital, in collaboration with pharmaceutical partners. A clinical trial program on precision-based hypofractionated stereotactic body radiotherapy (SBRT) is ongoing and rapidly being further developed. Most of these clinical trials are performed in conjunction with the Nordic SBRT study group, which is chaired by Prof. Lewensohn. SBRT seems promising in treatment of inoperable tumors, to improve survival of lung cancer patients. In several clinical trials, drug and radiotherapy are also combined as a novel strategy to cure patients with both early localized and early metastasized disease.
Furthermore, the group has a leading role in the EurocanPlatform, an EU-funded project to bring together 28 European cancer institutions and organizations, with the aim to improve outcomes for cancer patients and reduce mortality. Within the Karolinska Institute, and Karolinska university hospital, Rolf Lewensohn is the primary initiator of the development of a personalized cancer medicine program. The ultimate goal of this program is to individualize therapy at all stages of disease by quickly and efficiently translating the latest scientific advances into concrete improvements of the care for cancer patients.
Articles
- Journal article: CLINICAL AND TRANSLATIONAL SCIENCE. 2024;17(8):e13909
- Journal article: ACS SENSORS. 2024;9(6):2935-2945
- Journal article: ESMO OPEN. 2024;9:102781
- Article: ACTA ONCOLOGICA. 2023;62(12):1921-1930
- Article: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 2023;117(5):1222-1231
- Journal article: JOURNAL OF THORACIC ONCOLOGY. 2023;18(11):s353
- Journal article: JOURNAL OF THORACIC ONCOLOGY. 2023;18(11):s697
- Journal article: JCO GLOBAL ONCOLOGY. 2023;9(Supplement_1):113
- Article: LUNG CANCER. 2023;182:107292
- Article: CLINICAL AND TRANSLATIONAL SCIENCE. 2023;16(6):955-965
- Article: STUDIES IN HEALTH TECHNOLOGY AND INFORMATICS. 2023;302:18-22
- Article: BIOSENSORS AND BIOELECTRONICS. 2023;227:115142
- Journal article: RADIOTHERAPY AND ONCOLOGY. 2023;181:109492
- Article: CELL DEATH DISCOVERY. 2022;8(1):464
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2022;11(11):e12277
- Article: MOLECULAR ONCOLOGY. 2022;16(20):3620-3641
- Article: CLINICAL AND TRANSLATIONAL SCIENCE. 2022;15(10):2437-2447
- Article: TRANSLATIONAL LUNG CANCER RESEARCH. 2022;11(10):2064-2078
- Journal article: JOURNAL OF THORACIC ONCOLOGY. 2022;17(9):s156
- Journal article: JOURNAL OF THORACIC ONCOLOGY. 2022;17(9):s574
- Article: CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY. 2022;36:91-98
- Article: CELL DEATH DISCOVERY. 2022;8(1):284
- Article: TRANSLATIONAL LUNG CANCER RESEARCH. 2022;11(5):722-734
- Article: MARINE DRUGS. 2022;20(4):265
- Article: BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. 2022;130(4):513-521
- Article: BIOSENSORS AND BIOELECTRONICS. 2021;193:113568
- Article: MOLECULAR ONCOLOGY. 2021;15(11):2941-2957
- Journal article: JOURNAL OF THORACIC ONCOLOGY. 2021;16(10):s974
- Article: ACS APPLIED MATERIALS & INTERFACES. 2021;13(36):42513-42521
- Article: JOURNAL OF THORACIC ONCOLOGY. 2021;16(7):1200-1210
- Article: NANOSCALE ADVANCES. 2021;3(11):3053-3063
- Article: ACTA ONCOLOGICA. 2021;60(3):305-311
- Journal article: JOURNAL OF THORACIC ONCOLOGY. 2021;16(3):s620
- Article: CANCERS. 2021;13(5):1010
- Article: CANCERS. 2021;13(4):922
- Journal article: RADIOTHERAPY AND ONCOLOGY. 2020;152:s345-s346
- Article: LUNG CANCER. 2020;147:106-114
- Article: NPJ SYSTEMS BIOLOGY AND APPLICATIONS. 2020;6(1):25
- Article: CANCERS. 2020;12(7):E1804-1804
- Article: EUROPEAN JOURNAL OF CANCER. 2020;132:24-34
- Article: ACTA ONCOLOGICA. 2020;59(4):388-394
- Article: PHARMACOGENOMICS JOURNAL. 2020;20(2):179-191
- Article: PLOS ONE. 2020;15(10):e0240973
- Article: LUNG CANCER. 2020;139:111-117
- Article: ACTA ONCOLOGICA. 2019;58(8):1178-1186
- Article: ACS SENSORS. 2019;4(5):1399-1408
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2019;511(2):260-265
- Article: MOLECULAR ONCOLOGY. 2019;13(2):376-391
- Article: LUNG CANCER. 2018;124:45-52
- Article: MOLECULAR ONCOLOGY. 2018;12(9):1415-1428
- Article: LUNG CANCER. 2018;120:75-81
- Article: ACTA ONCOLOGICA. 2018;57(2):231-238
- Article: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 2018;100(1):174-187
- Article: RADIATION ONCOLOGY. 2017;12(1):206
- Journal article: JOURNAL OF THORACIC ONCOLOGY. 2017;12(11):s1922-s1923
- Journal article: JOURNAL OF THORACIC ONCOLOGY. 2017;12(11):s2114
- Journal article: ONCOGENE. 2017;36(33):4818
- Article: RADIOTHERAPY AND ONCOLOGY. 2016;121(1):1-8
- Article: ONCOTARGET. 2016;7(37):60332-60347
- Article: ONCOTARGET. 2016;7(37):59322-59335
- Article: ONCOTARGET. 2016;7(31):50258-50276
- Journal article: CANCER RESEARCH. 2016;76(14_Supplement):3355
- Article: MOLECULAR ONCOLOGY. 2016;10(5):719-734
- Article: CLINICAL CANCER RESEARCH. 2016;22(2):366-373
- Article: INVESTIGATIONAL NEW DRUGS. 2015;33(6):1232-1241
- Article: ACTA ONCOLOGICA. 2015;54(8):1096-1104
- Article: BMC CANCER. 2015;15:628
- Article: JOURNAL OF MOLECULAR DIAGNOSTICS. 2015;17(4):352-359
- Journal article: RADIOTHERAPY AND ONCOLOGY. 2015;115:s324-s325
- Article: CLINICAL PROTEOMICS. 2015;12(1):8
- Article: MOLECULAR CANCER THERAPEUTICS. 2014;13(12):2941-2954
- Article: RADIOTHERAPY AND ONCOLOGY. 2014;113(3):303-309
- Article: UROLOGIC ONCOLOGY: SEMINARS AND ORIGINAL INVESTIGATIONS. 2014;32(8):1215-1224
- Article: INTERNATIONAL JOURNAL OF RADIATION BIOLOGY. 2014;90(8):718-726
- Article: CELL DEATH AND DISEASE. 2014;5(3):e1111
- Journal article: RADIOTHERAPY AND ONCOLOGY. 2014;111:s221
- Journal article: BLOOD. 2013;122(21):2619
- Article: GENES CHROMOSOMES AND CANCER. 2013;52(10):895-911
- Article: JOURNAL OF PROTEOME RESEARCH. 2013;12(9):3934-3943
- Article: CANCER. 2013;119(16):3076-3083
- Article: ACTA ONCOLOGICA. 2013;52(6):1189-1194
- Article: MARINE DRUGS. 2013;11(7):2574-2594
- Article: ANTI-CANCER DRUGS. 2013;24(6):648-652
- Article: CLINICAL CANCER RESEARCH. 2013;19(11):3019-3031
- Article: ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. 2013;54(5):327-337
- Article: CELL DEATH AND DISEASE. 2013;4(1):e478
- Article: JOURNAL OF CONTEMPORARY BRACHYTHERAPY. 2012;4(4):205-212
- Article: BRITISH JOURNAL OF CANCER. 2012;107(8):1361-1373
- Journal article: ANNALS OF ONCOLOGY. 2012;23:v38
- Journal article: RADIOTHERAPY AND ONCOLOGY. 2012;103:s439-s440
- Journal article: MOLECULAR CANCER THERAPEUTICS. 2011;10(11_Supplement):b60
- Journal article: MOLECULAR CANCER THERAPEUTICS. 2011;10(11_Supplement):b40
- Journal article: MOLECULAR CANCER THERAPEUTICS. 2011;10(11_Supplement):a24
- Journal article: MOLECULAR CANCER THERAPEUTICS. 2011;10(11_Supplement):b52
- Article: RADIOTHERAPY AND ONCOLOGY. 2011;101(2):260-266
- Journal article: JOURNAL OF PROTEOME RESEARCH. 2011;10(10):4884
- Article: GENES & DEVELOPMENT. 2011;25(19):2031-2040
- Article: JOURNAL OF PROTEOME RESEARCH. 2011;10(5):2566-2578
- Article: ACTA ONCOLOGICA. 2011;50(4):518-527
- Article: EUROPEAN JOURNAL OF CANCER. 2011;47(1):131-137
- Journal article: BLOOD. 2010;116(21):2491
- Journal article: BLOOD. 2010;116(21):1838
- Article: BIOCHEMICAL PHARMACOLOGY. 2010;79(9):1281-1290
- Journal article: CANCER RESEARCH. 2010;70(8_Supplement):684
- Journal article: MOLECULAR CANCER THERAPEUTICS. 2009;8(12_Supplement):b187
- Journal article: MOLECULAR CANCER THERAPEUTICS. 2009;8(12_Supplement):b25
- Journal article: BLOOD. 2009;114(22):3466
- Article: ANNALS OF ONCOLOGY. 2009;20(10):1639-1646
- Article: BRITISH JOURNAL OF CANCER. 2009;101(5):816-821
- Article: JOURNAL OF CLINICAL ONCOLOGY. 2009;27(20):3290-3296
- Article: PROTEOMICS. 2009;9(13):3414-3424
- Article: EXPERIMENTAL HEMATOLOGY. 2009;37(6):755-766
- Article: MOLECULAR & CELLULAR PROTEOMICS. 2009;8(5):1117-1129
- Article: JOURNAL OF CHROMATOGRAPHY B: ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2009;877(13):1306-1316
- Article: JOURNAL OF NEURO-ONCOLOGY. 2009;92(2):137-147
- Article: LUNG CANCER. 2009;63(3):410-417
- Journal article: BLOOD. 2008;112(11):5041
- Journal article: BLOOD. 2008;112(11):4854
- Article: MOLECULAR CANCER RESEARCH. 2008;6(10):1630-1638
- Article: APMIS. 2008;116(10):888-895
- Article: RADIOTHERAPY AND ONCOLOGY. 2008;88(3):359-367
- Article: JOURNAL OF PROTEOME RESEARCH. 2008;7(7):2712-2722
- Article: JOURNAL OF PROTEOME RESEARCH. 2008;7(6):2332-2341
- Article: APMIS. 2008;116(6):491-498
- Article: MOLECULAR & CELLULAR PROTEOMICS. 2007;6(12):2122-2131
- Article: JOURNAL OF NEURO-ONCOLOGY. 2007;85(3):245-254
- Article: MOLECULAR CANCER THERAPEUTICS. 2007;6(9):2409-2417
- Journal article: JOURNAL OF THORACIC ONCOLOGY. 2007;2(8):s751-s752
- Journal article: JOURNAL OF THORACIC ONCOLOGY. 2007;2(8):s536
- Journal article: JOURNAL OF THORACIC ONCOLOGY. 2007;2(8):s614
- Article: MOLECULAR CANCER THERAPEUTICS. 2007;6(8):2303-2309
- Article: GROWTH FACTORS. 2007;25(1):1-8
- Article: PROTEOMICS. 2006;6(23):6124-6133
- Article: JOURNAL OF BIOTECHNOLOGY. 2006;126(4):582-586
- Article: BRITISH JOURNAL OF CANCER. 2006;94(11):1683-1689
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;342(4):1211-1217
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;341(2):334-342
- Article: INTERNATIONAL JOURNAL OF RADIATION BIOLOGY. 2006;82(2):87-96
- Journal article: BLOOD. 2005;106(11):2367
- Journal article: JOURNAL OF CLINICAL ONCOLOGY. 2005;23(16_suppl):699
- Article: CANCER LETTERS. 2005;222(2):173-181
- Article: EXPERIMENTAL CELL RESEARCH. 2005;305(1):200-213
- Article: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 2005;61(3):915-921
- Article: INVESTIGATIONAL NEW DRUGS. 2004;22(4):411-420
- Article: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 2004;60(2):395-400
- Article: EXPERIMENTAL CELL RESEARCH. 2004;298(1):83-95
- Article: EXPERIMENTAL AND MOLECULAR PATHOLOGY. 2004;77(1):1-6
- Journal article: JOURNAL OF CLINICAL ONCOLOGY. 2004;22(14_suppl):9615
- Journal article: JOURNAL OF CLINICAL ONCOLOGY. 2004;22(14_suppl):9615
- Article: CARCINOGENESIS. 2004;25(6):909-921
- Article: INTERNATIONAL JOURNAL OF RADIATION BIOLOGY. 2003;79(12):965-971
- Article: MOLECULAR CANCER THERAPEUTICS. 2003;2(12):1331-1339
- Article: CANCER BIOLOGY & THERAPY. 2003;2(6):663-669
- Article: EXPERIMENTAL CELL RESEARCH. 2003;289(2):256-264
- Article: INTERNATIONAL JOURNAL OF RADIATION BIOLOGY. 2003;79(8):611-621
- Article: JOURNAL OF DRUG TARGETING. 2003;11(6):355-363
- Article: ANTICANCER RESEARCH. 2003;23(3C):3077-3083
- Article: RADIATION RESEARCH. 2003;159(4):495-501
- Article: HEAD AND NECK. 2003;25(4):313-321
- Article: ONCOLOGY RESEARCH. 2003;14(3):113-132
- Article: EXPERIMENTAL CELL RESEARCH. 2002;279(2):277-290
- Article: CANCER LETTERS. 2002;180(2):191-194
- Article: ANTICANCER RESEARCH. 2002;22(3):1787-1793
- Article: LAKARTIDNINGEN. 2002;99(13):1453-1455
- Article: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2002;12(2):158-170
- Journal article: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2002;12(2):158-170
- Article: ONCOGENE. 2002;21(1):65-77
- Article: NUCLEAR INSTRUMENTS AND METHODS IN PHYSICS RESEARCH, SECTION B: BEAM INTERACTIONS WITH MATERIALS AND ATOMS. 2001;184(4):569-588
- Article: ONCOGENE. 2001;20(23):2877-2888
- Article: LAKARTIDNINGEN. 2001;98(21):2565-2566
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2001;283(4):726-731
- Article: INTERNATIONAL JOURNAL OF RADIATION BIOLOGY. 2001;77(3):309-317
- Article: INTERNATIONAL JOURNAL OF CANCER. 2001;96:43-53
- Article: ACTA ONCOLOGICA. 2001;40(5):566-573
- Article: ANTICANCER RESEARCH. 2001;21(1B):529-534
- Article: INTERNATIONAL JOURNAL OF RADIATION BIOLOGY. 2001;77(1):127-135
- Article: CANCER RESEARCH. 2000;60(22):6230-6235
- Journal article: LUNG CANCER. 2000;29(1):162
- Article: ANTICANCER RESEARCH. 2000;20(5A):3051-3058
- Article: INTERNATIONAL JOURNAL OF CANCER. 2000;89(3):300-304
- Article: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 1999;45(5):1259-1266
- Article: ANTI-CANCER DRUGS. 1999;10(10):921-928
- Article: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 1999;45(4):1005-1010
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1999;262(2):381-387
- Article: CELL PROLIFERATION. 1999;32(4):239-248
- Article: INTERNATIONAL JOURNAL OF RADIATION BIOLOGY. 1999;75(6):709-716
- Article: MUTATION RESEARCH - FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. 1999;425(1):9-20
- Article: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 1999;43(1):191-198
- Article: EUROPEAN JOURNAL OF CANCER. 1999;35(1):111-116
- Article: CANCER LETTERS. 1998;132(1-2):175-180
- Article: LUNG CANCER. 1998;22(1):1-13
- Article: BRITISH JOURNAL OF CANCER. 1998;78(3):328-335
- Article: JOURNAL OF CLINICAL ONCOLOGY. 1998;16(3):1054-1059
- Article: ANTICANCER RESEARCH. 1998;18(2A):695-699
- Article: INTERNATIONAL JOURNAL OF RADIATION BIOLOGY. 1998;73(2):169-177
- Article: BRITISH JOURNAL OF CANCER. 1998;77(4):643-649
- Article: ANTICANCER RESEARCH. 1997;17(5A):3381-3386
- Journal article: LUNG CANCER. 1997;18:166-167
- Article: EUROPEAN JOURNAL OF CANCER. 1997;33(6):942-949
- Article: CANCER EPIDEMIOLOGY. 1997;21(1):91-102
- Article: JOURNAL OF PHARMACEUTICAL SCIENCES. 1996;85(8):824-827
- Journal article: LAKARTIDNINGEN. 1995;92(44):4100-4105
- Journal article: LUNG CANCER. 1994;11(5-6):393-400
- Journal article: RADIATION RESEARCH. 1994;139(1):34-39
- Journal article: LAKARTIDNINGEN. 1994;91(22):2243-2246
- Journal article: LUNG CANCER. 1994;11:111
- Journal article: ACTA ONCOLOGICA. 1994;33(4):439-450
- Journal article: EUROPEAN JOURNAL OF CANCER. 1994;30A(5):710-713
- Journal article: EUROPEAN JOURNAL OF CANCER. 1993;29:s219
- Journal article: EUROPEAN JOURNAL OF CANCER. 1993;29:s124
- Journal article: EUROPEAN JOURNAL OF CANCER. 1993;29:s227
- Journal article: CANCER CHEMOTHERAPY AND PHARMACOLOGY. 1993;31(4):265-268
- Journal article: EUROPEAN JOURNAL OF CANCER. 1993;29:s166
- Journal article: ACTA ENDOCRINOLOGICA. 1992;127(4):294-300
- Journal article: LAKARTIDNINGEN. 1992;89(17):1480-1484
- Journal article: ANTI-CANCER DRUGS. 1991;2(6):565-570
- Journal article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1991;47(3):161-167
- Journal article: ANTICANCER RESEARCH. 1991;11(5):1725-1730
- Journal article: LUNG CANCER. 1991;7:127
- Journal article: ANTICANCER RESEARCH. 1991;11(1):321-324
- Journal article: MEDICAL ONCOLOGY AND TUMOR PHARMACOTHERAPY. 1991;8(4):265-269
- Journal article: MEDICAL ONCOLOGY AND TUMOR PHARMACOTHERAPY. 1991;8(2):63-67
- Journal article: EUROPEAN JOURNAL OF CANCER. 1990;26(3):393-396
- Journal article: ANTICANCER RESEARCH. 1990;10(2A):297-301
- Journal article: EUROPEAN JOURNAL OF CANCER AND CLINICAL ONCOLOGY. 1988;24(9):1505-1510
- Journal article: ACTA ONCOLOGICA. 1988;27(4):383-392
- Journal article: EUROPEAN JOURNAL OF CANCER AND CLINICAL ONCOLOGY. 1987;23(6):783-788
- Journal article: CANCER RESEARCH. 1987;47(10):2631-2637
- Journal article: ANTICANCER RESEARCH. 1987;7(1):97-104
- Journal article: PHOTO-DERMATOLOGY. 1985;2(6):401-406
- Journal article: ANTICANCER RESEARCH. 1985;5(5):471-478
- Journal article: MUTATION RESEARCH - FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. 1983;111(2):171-184
- Journal article: CANCER LETTERS. 1983;18(3):305-310
- Journal article: EUROPEAN JOURNAL OF CANCER AND CLINICAL ONCOLOGY. 1983;19(1):59-63
- Journal article: ANALYTICAL AND QUANTITATIVE CYTOLOGY. 1982;4(2):99-104
- Journal article: SCANDINAVIAN JOURNAL OF HAEMATOLOGY. 1982;28(5):399-407
- Journal article: JOURNAL OF CELL SCIENCE. 1982;54(APR):69-78
- Journal article: LAKARTIDNINGEN. 1982;79(10):904-905
- Journal article: CANCER RESEARCH. 1982;42(1):84-88
- Journal article: ACTA PATHOLOGICA ET MICROBIOLOGICA SCANDINAVICA - SECTION A PATHOLOGY. 1981;89(6):417-424
- Journal article: EUROPEAN JOURNAL OF CANCER AND CLINICAL ONCOLOGY. 1981;17(9):991-996
- Journal article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 1981;76(4):268-270
- Journal article: ACTA MEDICA SCANDINAVICA. 1981;210(5):381-387
- Journal article: BLOOD. 1980;55(2):311-316
- Journal article: BLOOD. 1980;55(2):311-316
- Journal article: BLOOD. 1979;54(6):1320-1329
- Journal article: BLOOD. 1979;54(6):1320-1329
- Journal article: EXPERIMENTAL CELL RESEARCH. 1979;123(1):107-110
- Journal article: ACTA MEDICA SCANDINAVICA. 1978;203(4):276-278
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All other publications
- Review: MOLECULAR ONCOLOGY. 2024;18(11):2612-2628
- Corrigendum: CELL DEATH DISCOVERY. 2022;8(1):472
- Preprint: RESEARCH SQUARE. 2022
- Letter: ACTA ONCOLOGICA. 2022;61(7):869-873
- Letter: JOURNAL OF THORACIC ONCOLOGY. 2021;16(10):e81-e82
- Preprint: BIORXIV. 2021
- Letter: ACTA ONCOLOGICA. 2020;59(1):28-32
- Conference publication: JOURNAL OF TRANSLATIONAL MEDICINE. 2020;18
- Conference publication: JOURNAL OF THORACIC ONCOLOGY. 2019;14(10):S814
- Conference publication: JOURNAL OF THORACIC ONCOLOGY. 2019;14(10):S842
- Meeting abstract: JOURNAL OF THORACIC ONCOLOGY. 2019;14(10):S784
- Meeting abstract: JOURNAL OF THORACIC ONCOLOGY. 2019;14(10):S568-S569
- Conference publication: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2019;7
- Published conference paper: RADIATION PROTECTION DOSIMETRY. 2018;182(1):80-84
- Conference publication: JOURNAL OF THORACIC ONCOLOGY. 2018;13(10):S976
- Corrigendum: LUNG CANCER. 2018;123:178-179
- Conference publication: EUROPEAN JOURNAL OF CANCER. 2018;103:E97
- Conference publication: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 2017;99(2):E474
- Meeting abstract: CANCER RESEARCH. 2017;77:5028
- Meeting abstract: CANCER RESEARCH. 2017;77:5026
- Conference publication: JOURNAL OF THORACIC ONCOLOGY. 2017;12(1):S340
- Conference publication: JOURNAL OF THORACIC ONCOLOGY. 2017;12(11):S2113
- Conference publication: JOURNAL OF THORACIC ONCOLOGY. 2017;12(1):S987
- Conference publication: JOURNAL OF THORACIC ONCOLOGY. 2017;12(11):S1921-S1922
- Meeting abstract: JOURNAL OF THORACIC ONCOLOGY. 2017;12(1):S1514
- Meeting abstract: JOURNAL OF THORACIC ONCOLOGY. 2017;12(1):S723-S724
- Meeting abstract: JOURNAL OF CLINICAL ONCOLOGY. 2016;34(15):e20096
- Meeting abstract: JOURNAL OF CLINICAL ONCOLOGY. 2016;34(15):e20031
- Conference publication: JOURNAL OF THORACIC ONCOLOGY. 2016;11(4):S96
- Conference publication: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 2015;93(3):E481-E482
- Conference publication: RADIOTHERAPY AND ONCOLOGY. 2015;115:S324-S325
- Book chapter: DEVELOPMENTS IN T CELL BASED CANCER IMMUNOTHERAPIES: CANCER DRUG DISCOVERY AND DEVELOPMENT. 2015;p. 211-229
- Meeting abstract: EUROPEAN JOURNAL OF CANCER. 2014;50:184
- Meeting abstract: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 2014;90:S780
- Conference publication: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 2014;90:S326
- Review: CELL DEATH AND DISEASE. 2014;5(5):e1260
- Meeting abstract: JOURNAL OF CLINICAL ONCOLOGY. 2014;32(15):e22239
- Conference publication: RADIOTHERAPY AND ONCOLOGY. 2014;111:S221
- Conference publication: MOLECULAR CANCER THERAPEUTICS. 2013;12(11):a170
- Meeting abstract: MOLECULAR CANCER THERAPEUTICS. 2013;12(11):b19
- Editorial comment: JOURNAL OF TRANSLATIONAL MEDICINE. 2012;10:104
- Conference publication: CANCER RESEARCH. 2011;71:p1-06-19-p1-06-19
- Meeting abstract: EUROPEAN JOURNAL OF CANCER. 2011;47:S124
- Conference publication: CANCER RESEARCH. 2011;71:4090
- Conference publication: CANCER RESEARCH. 2011;71:163
- Conference publication: CANCER RESEARCH. 2011;71:2541
- Meeting abstract: EJC SUPPLEMENTS. 2010;8(7):69
- Meeting abstract: EJC SUPPLEMENTS. 2010;8(5):134
- Meeting abstract: EJC SUPPLEMENTS. 2010;8(5):113
- Meeting abstract: EJC SUPPLEMENTS. 2010;8(5):134-135
- Meeting abstract: EJC SUPPLEMENTS. 2010;8(5):57
- Review: JOURNAL OF NEUROIMMUNE PHARMACOLOGY. 2010;5(1):4-17
- Review: PROTEOMICS. 2009;9(6):1420-1427
- Conference publication: LUNG CANCER. 2009;64:S13
- Conference publication: RADIOTHERAPY AND ONCOLOGY. 2008;88:S171-S172
- Review: TUMOR BIOLOGY. 2008;29(5):311-322
- Meeting abstract: JOURNAL OF THORACIC ONCOLOGY. 2007;2(8):S356-S357
- Editorial comment: JOURNAL OF THORACIC ONCOLOGY. 2007;2(3):175-179
- Published conference paper: ACTA ONCOLOGICA. 2006;45(7):973-977
- Published conference paper: ACTA ONCOLOGICA. 2006;45(7):787-795
- Corrigendum: EXPERIMENTAL AND MOLECULAR PATHOLOGY. 2005;79(1):86
- Review: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2005;331(3):868-880
- Review: ADVANCES IN CANCER RESEARCH. 2005;94:143-196
- Review: LUNG CANCER. 2003;41(1):1-11
- Corrigendum: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2001;284(4):1091
- Review: LAKARTIDNINGEN. 2000;97(3):164-167
- Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2000;926:204-216
- Published conference paper: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 1997;39(2):303-308
- Conference publication: PIGMENT CELL AND MELANOMA RESEARCH. 1988;1(4):288
- Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 1986;87(3):432
- Conference publication: PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH. 1986;27:235
- Conference publication: PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH. 1984;25(MAR):336
- Book chapter: CANCER CHEMOTHERAPY AND SELECTIVE DRUG DEVELOPMENT: DEVELOPMENTS IN ONCOLOGY. 1984;p. 539
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Grants
- Swedish Research Council1 January 2019 - 31 December 2022
- Development of new curative treatment for lung cancer using precision radiation therapy alone and combined with targeting drugs or immunotherapy.Swedish Cancer Society1 January 2018
- Molecular and clinical studies of lung cancer with the goal of creating improved and individualized treatment.Swedish Cancer Society1 January 2017
- VINNOVA11 April 2016 - 19 January 2017
- Molecular and clinical studies of lung cancer with the goal of creating improved and individualized treatment.Swedish Cancer Society1 January 2016
- National Workshop on ”Personalized Cancer Medicine” (PCM)Swedish Foundation for Strategic Research10 August 2015 - 30 June 2016
- Molecular and clinical studies of lung cancer with the goal of creating improved and individualized treatment.Swedish Cancer Society1 January 2015
- Molecular and clinical studies of lung cancer with the goal of creating improved and individualized treatment.Swedish Cancer Society1 January 2014
- Swedish Research Council1 January 2010 - 31 December 2012
Employments
- Professor, Department of Oncology-Pathology, Karolinska Institutet, 2020-
Degrees and Education
- Docent, Karolinska Institutet, 1982