Rodrigo Fernandez-Gonzalo
About me
I am an Associate Professor (Docent) in Physiology and Principal Researcher at the Division of Clinical Physiology.
I lead the Space & Environmental Physiology research group.
A significant part of my projects is conducted at the Human Physiology Lab (Humanlab).
Research
My research focuses on understanding how skeletal muscle mass and function are regulated under different conditions and situations, and how this tissue interacts with other physiological systems of the human body. In recent years, I have focused on studying the effects of unloading, severe inactivity and microgravity on the musculoskeletal system and how this tissue interacts with other physiological systems of the human body.
In my studies, I use a wide range of methods to analyze functional, metabolic, morphological, molecular and neural adaptations to short- or long-term muscle disuse (e.g. microgravity), aging, acute and chronic exercise, disease (e.g. cerebral palsy) and athletic performance. I use clinical studies in humans, experiments in mice, and cellular models to gain a comprehensive picture of the physiological processes underlying the regulation and interaction of the musculoskeletal and other organ systems.
Teaching
My general competence area is human physiology, with particular expertise in skeletal muscle physiology.
Since 2018, I have been the course responsible (kursansvarig) for anatomy and physiology (distance learning) within the bachelor’s degree programme in nursing at Karolinska Institutet.
Since 2023, I have been the course responsible for Advanced Human Physiology Research as part of the Master's programme in Translational Physiology and Pharmacology, at Karolinska Institutet.Since 2026, I am the examiner in the course Quality Assurance Applied to Clinical Research (doctoral education).
I am also involved in teaching activities in space and environmental physiology in Sweden and abroad.
Articles
- Journal article: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY. 2026;201:31-68Cools B; Smith MB; Boutouyrie P; Ciccone V; De Meulemeester P; Fernandez-Gonzalo R; Frippiat J-P; Oliver BGG; Gentile S; Goswami N; Grimm D; Gupta U; Akyuz SH; Corydon TJ; Kamarova M; Luderer U; Bell SM; Morbidelli L; Mushunuri A; Ritz J; Schulz H; Strollo F; Verde P; Vinken M
- Article: DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY. 2026;68(8):1139-1151Corell L; Hjalmarsson E; Fernandez-Gonzalo R; Kruse A; Edman S; Kizyte A; Wang R; Bos AE; Sorensson P; Ponten E; van Schie PEM; Buizer AI; Norrbom J; Cardinale DA; von Walden F
- Article: EXPERIMENTAL PHYSIOLOGY. 2026;111(8):3772-3783Horwath O; Corell L; Wan J; Hjalmarsson E; Starck J; Reitzner SM; Norrbom J; Fernandez-Gonzalo R; Kvist O; Cohen P; von Walden F; Edman S
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2026;604(12):4771-4794Martin-Rodriguez S; Mandic M; Laurens C; Bareille M-P; de Villemeur RB; Fernandez-Gonzalo R; Simon C
- Journal article: PLOS MEDICINE. 2026;23(6):e1005145Martin-Rodriguez S; Fernandez-Gonzalo R; Moher D
- Article: BREAST CANCER RESEARCH. 2026;28(1):98Zopf EM; Joernaker G; Clauss D; Trevaskis M; Hiensch AE; Schmidt ME; Monninkhof EM; Zimmer P; Belloso J; Heyrman E; Gonzalo RF; Wiskemann J; Mueller J; Bolam KA; Gorecki M; Altena R; Muttiah C; van der Wall E; Aaronson NK; Senkus E; Urruticoechea A; Stuiver MM; Steindorf K; Bloch W; Wengstrom Y; May AM; Rundqvist H
- Article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2026;126(3):1573-1587Carpenter TK; McCashland M; Sherrick R; Natarajan SK; Mandic M; Kachman SD; von Walden F; Vechetti IJ; Fernandez-Gonzalo R
- Article: EXPERIMENTAL PHYSIOLOGY. 2026;111(3):1181-1190Mandic M; Lundberg TR; Frippiat J-P; Mcdonnell AC; Mekjavic IB; Bareille M-P; Billette de Villemeur R; Fernandez-gonzalo R
- Article: COMMUNICATIONS MEDICINE. 2026;6(1):97Rullman E; Lovric A; Melin M; Fernandez-Gonzalo R; Gustafsson T
- Article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2025;125(12):3707-3717Sorrentino RG; Vovk A; Suput D; Ioannou LG; Mekjavic V; Fernandez-Gonzalo R; Supej M; Mekjavic IB
- Article: ADAPTED PHYSICAL ACTIVITY QUARTERLY. 2025;42(4):550-565Hjalmarsson E; Bos AE; Corell L; Kruse A; Fernandez-Gonzalo R; Norrbom J; Ponten E; van Schie P; Buizer AI; von Walden F
- Article: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE. 2025;16(5):e70085Tryfonos A; Jornaker G; Rundqvist H; Pourhamidi K; Melin M; Wallin H; Larsen FJ; Pantelios S; Mutvei AP; Tillander V; Tietge UJF; Diaz SP; Crafoord D; Lovric A; Fernandez-Gonzalo R; Rullman E; Stal P; Gustafsson T; Rundqvist H; Lundberg TR
- Journal article: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE. 2025;16(5):e70085Tryfonos A; Jörnåker G; Rundqvist H; Pourhamidi K; Melin M; Wallin H; Larsen FJ; Pantelios S; Mutvei AP; Tillander V; Tietge UJF; Diaz SP; Crafoord D; Lovric A; Fernandez-Gonzalo R; Rullman E; Stål P; Gustafsson T; Rundqvist H; Lundberg TR
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2025;603(14):3973-3986Perez-Diaz S; Baselet B; Lovric A; Lundberg TR; Neefs M; Daenen L; Rullman E; Fernandez-Gonzalo R
- Journal article: RESULTS IN ENGINEERING. 2025;26:105570Perez-Diaz S; Leon JG; Lopez-Ortiz S; Mandic M; Altun M; Rundqvist H; Gustafsson T; Fernandez-Gonzalo R
- Article: EMBO REPORTS. 2024;25(12):5810-5837The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growthEdman S; Jones RGIII; Jannig PR; Fernandez-Gonzalo R; Norrbom J; Thomas NT; Khadgi S; Koopmans PJ; Morena F; Chambers TL; Peterson CS; Scott LN; Greene NP; Figueiredo VC; Fry CS; Zhengye L; Lanner JT; Wen Y; Alkner B; Murach KA; von Walden F
- Journal article: GAIT & POSTURE. 2024;113:240-241Corell L; Hjalmarsson E; Fernandez-Gonzalo R; Edman S; Kizyte A; Wang R; Kruse A; Pontén E; Norrbom J; Von Walden F
- Article: DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY. 2024;66(7):902-909Kruse A; Imery I; Corell L; Hjalmarsson E; Fernandez-Gonzalo R; Von Walden F; Reitzner SM
- Article: EXPERIMENTAL PHYSIOLOGY. 2024;109(5):647-649Fernandez-Gonzalo R; Deane CS; Bailey D
- Article: BMC SPORTS SCIENCE MEDICINE AND REHABILITATION. 2024;16(1):45Lundberg TR; Larsson G; Alstermark R; Mandic M; Fernandez-Gonzalo R
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All other publications
- Review: EXPERIMENTAL PHYSIOLOGY. 2025;:10.1113/ep091737Fernandez-Gonzalo R; Schneider S; Heer M; Liphardt A-M
- Corrigendum: GEROSCIENCE. 2024;46(2):2799Rodriguez-Miguelez P; Fernandez-Gonzalo R; Almar M; Mejias Y; Rivas A; de Paz JA; Cuevas MJ; Gonzalez-Gallego J
- Preprint: BIORXIV. 2024;BIORXIVEdman S; Jones RG; Jannig PR; Fernandez-Gonzalo R; Norrbom J; Thomas NT; Khadgi S; Koopmans PJ; Morena F; Peterson CS; Scott LN; Greene NP; Figueiredo VC; Fry CS; Zhengye L; Lanner JT; Wen Y; Alkner B; Murach KA; von Walden F
- Review: SPORTS MEDICINE. 2024;54(3):541-556Beato M; de Keijzer KL; Munoz-Lopez A; Raya-Gonzalez J; Pozzo M; Alkner BA; Dello Iacono A; Vicens-Bordas J; Coratella G; Maroto-Izquierdo S; Gonzalo-Skok O; McErlain-Naylor SA; Martin-Rivera F; Hernandez-Davo JL; Arrones LS; Sabido R; de Hoyo M; Fernandez-Gonzalo R; Norrbrand L
- Corrigendum: AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2020;319(1):R59
- Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2020;52(7):325von Walden F; Hjalmarsson E; Fernandez-Gonzalo R; Palmcrantz A; Kvist O; Ponten E
- Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2020;52(7):923Fernandez-Gonzalo R; Hansson B; Emanuelsson E; Baselet B; Moreels M; Neefs M; Baatout S; Rundqvist H
- Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2020;52(7):475Hjalmarsson E; Fernandez-Gonzalo R; Pingel J; Santiago LB; Palmcrantz A; Ponten E; von Walden F
- Conference publication: FASEB JOURNAL. 2020;34:1von Walden F; Figueiredo V; Fernandez-Gonzalo R; Murach K; Mobley B; Norrbom J; McCarthy J; Alkner B
- Letter: JOURNAL OF APPLIED PHYSIOLOGY. 2020;128(2):460-461Sanz G; Martinez-Aranda LM; Tesch PA; Fernandez-Gonzalo R; Lundberg TR
- Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2019;51(6):146Fernandez-Gonzalo R; Tesch PA; Lundberg TR; Rullman E; Gustafsson T
- Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2019;51(6):145-146Lundberg TR; Hansson B; Olsen LA; von Walden F; Fernandez-Gonzalo R
- Review: CHROMATIN AND GENOMIC INSTABILITY IN CANCER. 2019;346:157-200Franco I; Fernandez-Gonzalo R; Vrtacnik P; Lundberg TR; Eriksson M; Gustafsson T
- Book chapter: SPORTS, EXERCISE, AND NUTRITIONAL GENOMICS. 2019;p. 509-538Estébanez B; Rodriguez-Miguelez P; Fernandez-Gonzalo R; González-Gallego J; Cuevas MJ
- Conference publication: FASEB JOURNAL. 2018;32(S1):768.7Norman B; Psilander N; Lilja M; Fernandez‐Gonzalo R; Lundberg T
- Letter: JOURNAL OF SCIENCE AND MEDICINE IN SPORT. 2018;21(3):230-231Maroto-Izquierdo S; Garcia-Lopez D; Fernandez-Gonzalo R; Moreira OC; Gonzalez-Gallego J; de Paz JA
- Review: JOURNAL OF SCIENCE AND MEDICINE IN SPORT. 2017;20(10):943-951Maroto-Izquierdo S; Garcia-Lopez D; Fernandez-Gonzalo R; Moreira OC; Gonzalez-Gallego J; de Paz JA
- Review: FRONTIERS IN PHYSIOLOGY. 2017;8:241Tesch PA; Fernandez-Gonzalo R; Lundberg TR
- Review: FRONTIERS IN IMMUNOLOGY. 2017;8:177-7Fernandez-Gonzalo R; Baatout S; Moreels M
- Review: JOURNAL OF APPLIED PHYSIOLOGY. 2016;120(10):1207-1214Tesch PA; Lundberg TR; Fernandez-Gonzalo R
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Grants
- Unloaded Minds – How prolonged unloading shapes human performance in lunar gravitySwedish National Space Agency1 January 2026 - 31 December 2027
- Unloaded Minds – How prolonged unloading shapes human performance in lunar gravityEuropean Space Agency, Swedish National Space Agency1 January 2026 - 31 December 2028
- The role of mechanotransduction and ubiquitin-proteosome system on skeletal muscle atrophyKarolinska Institutet1 January 2024 - 31 December 2027
- Single nuclei RNA sequencing in human skeletal muscle after unloadingGösta Fraenckel Foundation - KI Fonder1 August 2023 - 31 December 2026
- Mechanisms behind skeletal muscle and immune system alterations during spaceflightSwedish National Space Agency13 April 2022 - 31 December 2024
- Transcriptomic Regulation of Bedrest-Induced Muscle and Immune System Alterations - Investigating the Role of Long Non-Coding RNASwedish National Space Agency & European Space Agency1 January 2021 - 31 December 2026
Employments
- Principal Researcher, Department of Laboratory Medicine, Karolinska Institutet, 2022-
- Postdoctoral researcher, Physiology and Pharmacology, Karolinska Institutet, 2011-2023
Degrees and Education
- Docent, Karolinska Institutet, 2021
Supervision
Supervision to doctoral degree
- Mats Lilja, Effects of anti-inflammatory drugs on human skeletal muscle adaptations to resistance training, 2023