Rasmus Gustafsson
Affiliated to Research
E-mail: rasmus.gustafsson@ki.se
Visiting address: L8:05, CMM Karolinska Universitetssjukhuset Solna, 17176 Stockholm
Postal address: K8 Klinisk neurovetenskap, K8 Neuro Kockum, 171 77 Stockholm
About me
- *Publication list*
1. Lundström W, *Gustafsson R*. Human Herpesvirus 6A Is a Risk
Factor for Multiple Sclerosis. Front Immunol. 2022 Feb 10 - 13:840753. doi:
10.3389/fimmu.2022.840753.
2. Viktor Grut, Martin Biström, Jonatan Salzer, Pernilla Stridh,
Daniel Jons, *Rasmus Gustafsson*, Anna Fogdell-Hahn, Jesse Huang, Nicole
Brenner, Julia Butt, Noemi Bender, Anna Lindam, Lucia Alonso-Magdalena,
Martin Gunnarsson, Magnus Vrethem, Tomas Bergström, Oluf Andersen, Ingrid
Kockum, Tim Waterboer, Tomas Olsson, Peter Sundström. Cytomegalovirus
seropositivity is associated with reduced risk of multiple sclerosis – a
presymptomatic case-control study. Eur J Neurol. 2021 Jun 9. Doi:
10.1111/ene.14961.
3. Jing Wu, Elin Engdahl, *Rasmus Gustafsson*, Anna Fogdell-Hahn, Tim
Waterboer, Jan Hillert, Tomas Olsson, Lars Alfredsson, Anna Karin Hedström.
High antibody levels against HHV-6A interact with lifestyle factors in MS
development. Mult Scler. 2021 Jun 14. doi: 10.1177/13524585211022011.
4. *Gustafsson R*. Human Herpesvirus 6A Induces Dendritic Cell Death
and HMGB1 Release without Virus Replication. Pathogens. 2021 Jan 11 - 10(1):57.
doi: 10.3390/pathogens10010057.
5. M. Biström, D. Jons, Engdahl E, *Gustafsson R*, Huang J, Brenner
N, Butt J, Alonso-Magdalena L, Gunnarsson M, Vrethem M, Bender N, Waterboer
T, Granåsen G, Olsson T, Kockum I, Andersen O, Fogdell-Hahn A, Sundström P.
Epstein-Barr virus infection after adolescence and human herpesvirus 6A as
risk factors for multiple sclerosis. European Journal of Neurology Eur J
Neurol. 2021 Feb - 28(2):579-586. doi: 10.1111/ene.14597. Epub 2020 Nov 22
6. Magnus Hansson, Rasmus Gustafsson, Chloé Jacquet
,
Nedia Chebaane, Simon Satchell, Therese Thunberg, Clas Ahlm and Anne-Marie
Fors Connolly (2020). Cystatin C and α-1-Microglobulin Predict Severe Acute
Kidney Injury in Patients with Hemorrhagic Fever with Renal Syndrome.
Pathogens 2020, 9, 666 - doi:10.3390/pathogens9080666
7. Engdahl E, Gustafsson R, Huang J, Biström M, Lima Bomfim I,
Stridh P, Khademi M, Brenner N, Butt J, Michel A, Jons D, Hortlund M,
Alonso-Magdalena L, Hedström AK, Flamand L, Ihira M, Yoshikawa T, Andersen
O, Hillert J, Alfredsson L, Waterboer T, Sundström P, Olsson T, Kockum I and
Fogdell-Hahn A. (2019). Increased Serological Response Against Human
Herpesvirus 6A Is Associated With Risk for Multiple Sclerosis. Front.
Immunol. 10:2715. doi: 10.3389/fimmu.2019.02715
8.
*K.L.R. Gustafsson* [1], T.Renné [2], C.Söderberg-Naucler [3], L.M.Butler
[4]. Human cytomegalovirus replication induces endothelial cell
interleukin-11. Cytokine. 2018 Maj 25. doi.org/10.1016/j.cyto.2018.05.018
[5].
9. *Rasmus Gustafsson*, Hannah C. Jeffery, Koon-Chu Yaiw, Vanessa
Wilhelmi, Ourania N. Kostopoulou, Belghis Davoudi, Afsar Rahbar, Melinda
Benard, Thomas Renné, Cecilia Söderberg-Nauclér, and Lynn M. Butler.
Direct infection of primary endothelial cells with human cytomegalovirus
prevents angiogenesis and migration. J Gen Virol. 2015 Sep 28. doi:
10.1099/jgv.0.000301.
10. *Gustafsson R*, Svensson M and Fogdell-Hahn A (2015) Modulatory effects
on dendritic cells by human herpesvirus 6. Front. Microbiol. 6:388. doi:
10.3389/fmicb.2015.00388.
11. Nicole Marquardt, Martin A. Ivarsson, Kim Blom, Veronica D. Gonzalez,
Monika Braun, Karolin Falconer, *Rasmus Gustafsson*, Anna Fogdell-Hahn, Johan
K. Sandberg, and Jakob Michaëlsson. The human NK cell response to yellow
fever virus vaccination is largely governed by NK cell differentiation
independently of NK cell education. The Journal of Immunology 08/2015
DOI:10.4049/jimmunol.1401811.
12. Elin Engdahl, *Rasmus Gustafsson*, Ryan Ramanujam, Emilie Sundqvist,
Tomas Olsson, Jan Hillert, Lars Alfredsson, Ingrid Kockum, Anna Fogdell-Hahn.
HLA-A*02 carriership, gender and tobacco smoking, but not multiple sclerosis,
affects the IgG antibody response against human herpesvirus 6. Human
Immunology 2014 Jun- 75(6):524-30. doi: 10.1016/j.humimm.2014.03.001.
13. *Gustafsson, R.*, R. Reitsma, A. Stralfors, A. Lindholm, R. Press, and
A. Fogdell-Hahn. 2013. Incidence of human herpesvirus 6 in clinical samples
from Swedish patients with demyelinating diseases. Journal of microbiology,
immunology, and infection. 2013 May 31. doi:pii: S1684-1182(13)00062-5.
10.1016/j.jmii.2013.03.009.
14. *Gustafsson, R. K.*, E. E. Engdahl, O. Hammarfjord, S. B. Adikari, M.
Lourda, J. Klingstrom, M. Svensson, and A. Fogdell-Hahn. 2013. Human
herpesvirus 6A partially suppresses functional properties of DC without viral
replication. PLoS ONE 8:e58122.
15. *Gustafsson, R. K.*, E. E. Engdahl, and A. Fogdell-Hahn. 2012.
Development and validation of a Q-PCR based TCID50 method for human
herpesvirus 6. Virol J 9:311.
16. Hoof, I., C. L. Perez, M. Buggert, *R. K. Gustafsson*, M. Nielsen, O.
Lund, and A. C. Karlsson. 2010. Interdisciplinary analysis of HIV-specific
CD8+ T cell responses against variant epitopes reveals restricted TCR
promiscuity. J Immunol 184:5383-5391.
17. Perez, C. L., M. V. Larsen, *R. Gustafsson*, M. M. Norstrom, A. Atlas,
D. F. Nixon, M. Nielsen, O. Lund, and A. C. Karlsson. 2008. Broadly
immunogenic HLA class I supertype-restricted elite CTL epitopes recognized in
a diverse population infected with different HIV-1 subtypes. J Immunol
180:5092-5100.
*Commisions of trust*
1. Member of the scientific reviewer board of the journal Pathogens
(Basel, Switzerland). 2021-present.
* *
*Selected grants*
1) Research grant from the foundation ”Stiftelsen för Gamla
tjänarinnor” for project on HHV-6 and Alzheimer’s disease, 2020.
2) Travel grant as invited speaker at the 11th International Conference on
HHV-6 & - 7, Quebec City, Canada, 2019.
3) Research grant from Neuro Sweden for project on host genetics and HHV-6
immunity, 2015.
4) Research grant from The Swedish Association of Persons with Neurological
Disabilities for project on the effect of HHV-6A on dendritic cells,
2012.
5) Research grant from the HHV-6 foundation, Santa Barbara, CA, for project
on development of a TCID50 method for HHV-6A and HHV-6B, 2011.
6) Travel grant from Scandinavian Society for Immunology for the 7th
International Conference on HHV-6 & - 7 [6], Reston, Virginia, USA, 2011.
7) Faculty funds from the Board of Doctoral Education at Karolinska
Institutet, KID, 2008-2012.
*Educations*
1. PhD degree 2013-12-06 from the Karolinska Institute. Thesis title:
Human herpesvirus 6 in multiple sclerosis: Assay development, immune
responses and host genetics.
2. Master of Science in Engineering, Biotechnology, focus on
molecular biology and pharmacology. Lund University, Sweden 2001-2007. Master
thesis approved 2007.
*Courses*
1. Teaching and Learning in Higher Education. 7, 5 hp. Karolinska
Institutet, Stockholm. Ongoing 2022
2. Introductory Doctoral Supervision course, four days. Karolinska
Institutet, Stockholm. 2020
3. Basic course for project management (XLPM), three days. Semcon AB,
Stockholm. 2019
4. Sociology 1-20 p, Lund University, Sweden, autumn semester 2003.
[1] https://www-sciencedirect-com.proxy.kib.ki.se/science/article/pii/S1043466618302175?via%3Dihub#!
[2] https://www-sciencedirect-com.proxy.kib.ki.se/science/article/pii/S1043466618302175?via%3Dihub#!
[3] https://www-sciencedirect-com.proxy.kib.ki.se/science/article/pii/S1043466618302175?via%3Dihub#!
[4] https://www-sciencedirect-com.proxy.kib.ki.se/science/article/pii/S1043466618302175?via%3Dihub#!
[5] https://doi-org.proxy.kib.ki.se/10.1016/j.cyto.2018.05.018
[6] http://www.hhv-6conference.com/index.php
Teaching
- *Pedagogical commitments*
1) Supervisor for Katie Healy, PhD student from Karolinska Institutet,
Autumn sem. 2021.
2) Supervisor for Jacob Degenne, master student from KTH. Spring sem. 2021.
3) Supervisor for Anna Malin Hallberg, master student from Lund University.
Autumn sem. 2020.
4) Supervisor for Josefine Sundgren, master student from Lund University.
Spring sem. 2020.
5) Mentor for Qian Xiao, architect student from China. Via The Swedish
Association of Graduate Engineers. 2019
6) Co-supervisor for PhD student Ivan Kmezic. Karolinska Institutet.
2018-present.
7) Mentor for Saraa Wahdan, newly arrived bio-technician from Iraq to
Sweden. Via The Swedish Association of Graduate Engineers. 2018.
8) Supervisor for Silvia Karlberg, bachelor student from Karolinska
Institutet. Spring sem. 2017.
9) Supervisor for master student Ajay Waghmare from Skövde University.
Autumn sem. 2015.
10) Solely responsible for PhD course in Neurovirology, 20 participants.
Autumn sem. 2011.
Articles
- Article: BRAIN. 2024;147(1):177-185
- Article: JOURNAL OF INFECTIOUS DISEASES. 2023;227(10):1214-1218
- Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1241199
- Article: JOURNAL OF VIRAL HEPATITIS. 2022;29(9):835-839
- Article: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3):383-392
- Article: EUROPEAN JOURNAL OF NEUROLOGY. 2021;28(9):3072-3079
- Article: EUROPEAN JOURNAL OF NEUROLOGY. 2021;28(2):579-586
- Article: PATHOGENS. 2021;10(1):57
- Article: PATHOGENS. 2020;9(8):E666-666
- Article: FRONTIERS IN IMMUNOLOGY. 2019;10:2715
- Article: CYTOKINE. 2018;111:563-566
- Article: JOURNAL OF GENERAL VIROLOGY. 2015;96(12):3598-3612
- Article: JOURNAL OF IMMUNOLOGY. 2015;195(7):3262-3272
- Article: JOURNAL OF MICROBIOLOGY, IMMUNOLOGY AND INFECTION. 2014;47(5):418-421
- Article: HUMAN IMMUNOLOGY. 2014;75(6):524-530
- Article: PLOS ONE. 2013;8(3):e58122
- Article: VIROLOGY JOURNAL. 2012;9:311
- Article: JOURNAL OF IMMUNOLOGY. 2010;184(9):5383-5391
- Article: JOURNAL OF IMMUNOLOGY. 2008;180(7):5092-5100
All other publications
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:237-238
- Conference publication: JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM. 2022;27:S66-S67
- Review: FRONTIERS IN IMMUNOLOGY. 2022;13:840753
- Conference publication: JOURNAL OF VASCULAR RESEARCH. 2019;56:35
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2019;25:81-82
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2016;22:187
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2016;22:859-860
- Review: FRONTIERS IN MICROBIOLOGY. 2015;6:388
- Thesis / dissertation: 2013
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2012;76(2):201
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2010;71(6):529
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;68(2):241
Employments
- Affiliated to Research, Department of Clinical Neuroscience, Karolinska Institutet, 2023-2025
Degrees and Education
- Degree Of Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2014