Per Roos | Karolinska Institutet

Publications
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Articles

Article: BIOMOLECULES. 2024;14(6):652
Hereditary Transthyretin Amyloidosis (hATTR) with Polyneuropathy Clusters Are Located in Ancient Mining Districts: A Possible Geochemical Origin of the Disease
Roos PM; Warmlander SKTS
Article: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2024;81:127348
Blood lead concentrations in exposed forecourt attendants and taxi drivers in parts of South Africa
Olowoyo JO; Tshoni UA; Kobyana AS; Lion GN; Mugivhisa LL; Koski L; Warmlander SKTS; Roos PM
Article: ACS CHEMICAL NEUROSCIENCE. 2023;14(15):2618-2633
Characterization of Uranyl (UO₂ ²⁺) Ion Binding to Amyloid Beta (Aβ) Peptides: Effects on Aβ Structure and Aggregation
Berntsson E; Vosough F; Noormagi A; Padari K; Asplund F; Gielnik M; Paul S; Jarvet J; Tougu V; Roos PM; Kozak M; Graslund A; Barth A; Pooga M; Palumaa P; Warmlander SKTS
Article: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2023;78:127163
Metal ratios as possible biomarkers for amyotrophic lateral sclerosis
Koski L; Berntsson E; Vikstrom M; Warmlander SKTS; Roos PM
Article: SCIENTIFIC REPORTS. 2023;13(1):3341
Residue-specific binding of Ni(II) ions influences the structure and aggregation of amyloid beta (Aβ) peptides
Berntsson E; Vosough F; Svantesson T; Pansieri J; Iashchishyn IA; Ostojic L; Dong X; Paul S; Jarvet J; Roos PM; Barth A; Morozova-Roche LA; Graslund A; Warmlander SKTS
Article: SCIENCE OF THE TOTAL ENVIRONMENT. 2022;841:156672
Geochemistry of multiple sclerosis in Finland
Astrom ME; Roos PM
Article: ACS OMEGA. 2022;7(33):28924-28931
Mercury Ion Binding to Apolipoprotein E Variants ApoE2, ApoE3, and ApoE4: Similar Binding Affinities but Different Structure Induction Effects
Berntsson E; Sardis M; Noormagi A; Jarvet J; Roos PM; Tougu V; Graslund A; Palumaa P; Warmlander SKTS
Article: BIOLOGICAL TRACE ELEMENT RESEARCH. 2021;199(10):3618-3624
Amyotrophic Lateral Sclerosis After Exposure to Manganese from Traditional Medicine Procedures in Kenya
Roos E; Warmlander SKTS; Meyer J; Sholts SB; Jarvet J; Graslund A; Roos PM
Article: ACTA BIOCHIMICA POLONICA. 2021;68(2):169-179
Lithium ions display weak interaction with amyloid-beta (Aβ) peptides and have minor effects on their aggregation
Berntsson E; Paul S; Vosough F; Sholts SB; Jarvet J; Roos PM; Barth A; Graslund A; Warmlander S
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2020;27(10):1913-1917
Interleukin-1 receptor antagonist, interleukin-2 receptor alpha subunit and amyotrophic lateral sclerosis
Yuan S; Roos PM; Larsson SC
Article: NEUROBIOLOGY OF AGING. 2020;87:140.e1-140.e3
Serum 25-hydroxyvitamin D in amyotrophic lateral sclerosis: mendelian randomization study
Larsson SC; Roos PM
Article: BIOMOLECULES. 2019;10(1):E44-44
Mercury and Alzheimer's Disease: Hg(II) Ions Display Specific Binding to the Amyloid-β Peptide and Hinder Its Fibrillization
Wallin C; Friedemann M; Sholts SB; Noormaegi A; Svantesson T; Jarvet J; Roos PM; Palumaa P; Graslund A; Waermlaender SKTS
Article: SCIENTIFIC REPORTS. 2017;7(1):14423
Alzheimer's disease and cigarette smoke components: effects of nicotine, PAHs, and Cd(II), Cr(III), Pb(II), Pb(IV) ions on amyloid-β peptide aggregation
Wallin C; Sholts SB; Osterlund N; Luo J; Jarvet J; Roos PM; Ilag L; Graslund A; Warmlander SKTS
Article: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2016;38:183-193
Characterization of Mn(II) ion binding to the amyloid-β peptide in Alzheimer's disease
Wallin C; Kulkarni YS; Abelein A; Jarvet J; Liao Q; Strodel B; Olsson L; Luo J; Abrahams JP; Sholts SB; Roos PM; Kamerlin SCL; Graslund A; Warmlander SKTS
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2016;54(3):971-982
Specific Binding of Cu(II) Ions to Amyloid-Beta Peptides Bound to Aggregation-Inhibiting Molecules or SDS Micelles Creates Complexes that Generate Radical Oxygen Species
Tiiman A; Luo J; Wallin C; Olsson L; Lindgren J; Jarvet J; Roose P; Sholts SB; Rahimipour S; Abrahams JP; Karlstrom AE; Graslund A; Warmlander SKTS
Article: BIOMETALS. 2016;29(5):827-839
Treatment strategies in Alzheimer's disease: a review with focus on selenium supplementation
Aaseth J; Alexander J; Bjorklund G; Hestad K; Dusek P; Roos PM; Alehagen U
Article: NEUROLOGY. 2016;86(24):2271-2277
Depression in amyotrophic lateral sclerosis
Roos E; Mariosa D; Ingre C; Lundholm C; Wirdefeldt K; Roos PM; Fang F
Article: BIOLOGICAL TRACE ELEMENT RESEARCH. 2013;151(2):159-170
Metal Concentrations in Cerebrospinal Fluid and Blood Plasma from Patients with Amyotrophic Lateral Sclerosis
Roos PM; Vesterberg O; Syversen T; Flaten TP; Nordberg M
Article: BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. 2012;111(2):126-132
Mercury in the Spinal Cord After Inhalation of Mercury
Roos PM; Dencker L
Article: EXPERIMENTAL BIOLOGY AND MEDICINE. 2012;237(7):803-810
Manganese in cerebrospinal fluid and blood plasma of patients with amyotrophic lateral sclerosis
Roos PM; Lierhagen S; Flaten TP; Syversen T; Vesterberg O; Nordberg M
Article: BRAIN RESEARCH. 2007;1174:136-142
Separation of proteins including metallothionein in cerebrospinal fluid by size exclusion HPLC and determination of trace elements by HR-ICP-MS
Gellein K; Roos PM; Evje L; Vesterberge O; Flaten TP; Nordberg M; Syversen T
Article: AMYOTROPHIC LATERAL SCLEROSIS. 2006;7(3):183-186
ALS: Cytokine profile in cerebrospinal fluid T-cell clones
Holmoy T; Roos PM; Kvale EO
Article: LUPUS. 2004;13(10):817-819
Respiratory arrest in systemic lupus erythematosus due to phrenic nerve neuropathy
Omdal R; Roos P; Wildhagen K; Gunnarsson R
Journal article: THE FEBS JOURNAL. 1980;108(1):279-283
ON THE MECHANISM OF ELEVATED PROSTAGLANDIN-E2 PRODUCTION IN 3T3 FIBROBLASTS TRANSFORMED BY POLYOMA-VIRUS
ROOS P; LINDGREN JA; HAMMARSTROM S
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All other publications

Review: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2023;78:127165
Metal concentrations in cerebrospinal fluid, blood, serum, plasma, hair, and nails in amyotrophic lateral sclerosis: A systematic review and meta-analysis
Kamalian A; Foroughmand I; Koski L; Darvish M; Saghazadeh A; Kamalian A; Razavi SZE; Abdi S; Dehgolan SR; Fotouhi A; Roos PM
Preprint: MEDRXIV. 2023
Occupational lead exposure in gasoline station forecourt attendants and other occupations in relation to ALS (amyotrophic lateral sclerosis) risk
Koski L; Tshoni UA; Olowoyo JO; Kobyana AS; Lion NG; Mugivhisa LL; Wärmländer SKTS; Roos PM
Preprint: MEDRXIV. 2023
Blood lead concentrations in exposed forecourt attendants and taxi drivers in parts of South Africa
Olowoyo JO; Tshoni UA; Kobyana AS; Lion GN; Mugivhisa LL; Koski L; Wärmländer SKTS; Roos PM
Preprint: BIORXIV. 2023
Characterization of uranyl (UO22+) ion binding to amyloid beta (Aβ) peptides: effects on Aβ structure and aggregation
Berntsson E; Vosough F; Noormägi A; Padari K; Asplund F; Gielnik M; Paul S; Jarvet J; Tõugu V; Roos PM; Kozak M; Gräslund A; Barth A; Pooga M; Palumaa P; Wärmländer SKTS
Letter: SCIENCE OF THE TOTAL ENVIRONMENT. 2023;859(Pt 2):160367
Comments on Letter to the Editor by Ph. D. Jussi Sipila regarding our paper "Geochemistry of multiple sclerosis in Finland "
Astrom ME; Roos PM
Review: BIOMOLECULES. 2022;12(5):714
Cerebral Iron Deposition in Neurodegeneration
Dusek P; Hofer T; Alexander J; Roos PM; Aaseth JO
Preprint: SSRN ELECTRONIC JOURNAL. 2022
Geochemistry of Multiple Sclerosis in Finland
Roos PM; Åström ME
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(22):12193
Metals in ALS TDP-43 Pathology
Koski L; Ronnevi C; Berntsson E; Warmlander SKTS; Roos PM
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(17):9461
Copper, Iron, Selenium and Lipo-Glycemic Dysmetabolism in Alzheimer's Disease
Aaseth J; Skalny AV; Roos PM; Alexander J; Aschner M; Tinkov AA
Preprint: BIORXIV. 2021
Lithium ions display weak interaction with amyloid-beta (Aβ) peptides and have minor effects on their aggregation
Berntsson E; Paul S; Vosough F; Sholts SB; Jarvet J; Roos PM; Barth A; Gräslund A; Wärmländer SKTS
Published conference paper: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2019;52:48-52
Ultraclean paired sampling for metal analysis in neurodegenerative disorders
Roos PM
Review: BIOMETALS. 2018;31(5):737-747
Prevention of progression in Parkinson's disease
Aaseth J; Dusek P; Roos PM
Conference publication: BIOPHYSICAL JOURNAL. 2018;114(3):219A
Mercury and Alzheimers Disease: HG(II) Ions Display Specific Binding to the Amyloid-Beta Peptide and Modulate its Aggregation
Warmlander S; Wallin C; Sholts S; Roos P; Jarvet J; Graslund A
Conference publication: FEBS OPEN BIO. 2018;8:34
Metal chemistry in neurodegenerative disorders
Roos PM
Book chapter: BIOMETALS IN NEURODEGENERATIVE DISEASES. 2017;p. 175-193
Chapter 10 Metals and Motor Neuron Disease
Roos PM
Published conference paper: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2015;31:193-203
The neurotoxicity of iron, copper and manganese in Parkinson's and Wilson's diseases
Dusek P; Roos PM; Litwin T; Schneider SA; Flaten TP; Aaseth J
Review: CLINICAL EPIDEMIOLOGY. 2015;7:181-193
Risk factors for amyotrophic lateral sclerosis
Ingre C; Roos PM; Piehl F; Kamel F; Fang F
Published conference paper: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2015;31:183-187
Iron and copper in progressive demyelination - New lessons from Skogholt's disease
Aspli KT; Flaten TP; Roos PM; Holmoy T; Skogholt JH; Aaseth J
Published conference paper: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2014;28(4):418-421
Osteoporosis in neurodegeneration
Roos PM
Thesis / dissertation: 2013
Studies on metals in motor neuron disease
Roos, Per M
Editorial comment: ACTA NEUROLOGICA SCANDINAVICA. 2011;124(3):215-217
Inclusion body myositis in Alzheimer's disease
Roos PM; Vesterberg O; Nordberg M
Letter: EUROPEAN NEUROLOGY. 2007;58(1):57-58
Slowly progressing amyotrophic lateral sclerosis caused by H46R SOD1 mutation
Holmoy T; Bjorgo K; Roos PM
Published conference paper: EXPERIMENTAL BIOLOGY AND MEDICINE. 2006;231(9):1481-1487
Metals in motor neuron diseases
Roos PM; Vesterberg O; Nordberg M
Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2004;11:190
Inclusion body myositis in dementia of Alzheimer type
Roos PM
Conference publication: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2002;199:S50-S51
Inclusion body myositis and Alzheimer
Roos PM
Book chapter: CHEMISTRY, BIOCHEMISTRY, AND PHARMACOLOGICAL ACTIVITY OF PROSTANOIDS. 1979;p. 221-232
BIOSYNTHESIS OF PROSTAGLANDINS AND THROMBOXANES
Hammarström S; Lindgren JÅ; Roos P
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Grants

The Kamprad family foundation for research

Employments

Affiliated to Research, Department of Clinical Neuroscience, Karolinska Institutet, 2024-2026

Degrees and Education

Degree Of Doctor Of Philosophy, Institute of Environmental Medicine, Karolinska Institutet, 2013

News from KI

Events from KI

Presentations

Presentation (slides etc.): JOURNAL OF THE NEUROLOGICAL SCIENCES. 2023;:121072
Geochemistry of multiple sclerosis in Finland
Roos P