Per M Roos | Karolinska Institutet

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Articles

Article: SCIENTIFIC REPORTS. 2025;15(1):5439
Molecular interactions, structural effects, and binding affinities between silver ions (Ag⁺) and amyloid beta (Aβ) peptides
Lakela AL; Berntsson E; Vosough F; Jarvet J; Paul S; Barth A; Graslund A; Roos PM; Warmlander SKTS
Journal article: BIOMOLECULES. 2024;14(6):652
Hereditary Transthyretin Amyloidosis (hATTR) with Polyneuropathy Clusters Are Located in Ancient Mining Districts: A Possible Geochemical Origin of the Disease.
Roos PM; Wärmländer SKTS
Article: BIOMOLECULES. 2024;14(6):652
Hereditary Transthyretin Amyloidosis (hATTR) with Polyneuropathy Clusters Are Located in Ancient Mining Districts: A Possible Geochemical Origin of the Disease
Roos PM; Warmlander SKTS
Article: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2024;81:127348
Blood lead concentrations in exposed forecourt attendants and taxi drivers in parts of South Africa
Olowoyo JO; Tshoni UA; Kobyana AS; Lion GN; Mugivhisa LL; Koski L; Warmlander SKTS; Roos PM
Journal article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2023;455:121717
Metal ratios as possible biomarkers for amyotrophic lateral sclerosis
Roos P; Koski L; Warmlonder S; Vikstrom M; Berntsson E
Journal article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2023;455:121716
Metal concentrations in cerebrospinal fluid, blood, serum, plasma, hair, and nails in amyotrophic lateral sclerosis: A systematic review and meta-analysis
Roos P; Kamalian A; Koski L; Foroughmand I; Darvish M; Kamalian A; Fotouhi A; Razavi ZE; Abdi S; Dehgolan SR
Journal article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2023;455:121715
The metal chemistry of motor neuron disease
Roos P
Article: ACS CHEMICAL NEUROSCIENCE. 2023;14(15):2618-2633
Characterization of Uranyl (UO₂ ²⁺) Ion Binding to Amyloid Beta (Aβ) Peptides: Effects on Aβ Structure and Aggregation
Berntsson E; Vosough F; Noormagi A; Padari K; Asplund F; Gielnik M; Paul S; Jarvet J; Tougu V; Roos PM; Kozak M; Graslund A; Barth A; Pooga M; Palumaa P; Warmlander SKTS
Article: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2023;78:127163
Metal ratios as possible biomarkers for amyotrophic lateral sclerosis
Koski L; Berntsson E; Vikstrom M; Warmlander SKTS; Roos PM
Article: SCIENTIFIC REPORTS. 2023;13(1):3341
Residue-specific binding of Ni(II) ions influences the structure and aggregation of amyloid beta (Aβ) peptides
Berntsson E; Vosough F; Svantesson T; Pansieri J; Iashchishyn IA; Ostojic L; Dong X; Paul S; Jarvet J; Roos PM; Barth A; Morozova-Roche LA; Graslund A; Warmlander SKTS
Article: SCIENCE OF THE TOTAL ENVIRONMENT. 2022;841:156672
Geochemistry of multiple sclerosis in Finland
Astrom ME; Roos PM
Article: ACS OMEGA. 2022;7(33):28924-28931
Mercury Ion Binding to Apolipoprotein E Variants ApoE2, ApoE3, and ApoE4: Similar Binding Affinities but Different Structure Induction Effects
Berntsson E; Sardis M; Noormagi A; Jarvet J; Roos PM; Tougu V; Graslund A; Palumaa P; Warmlander SKTS
Article: BIOLOGICAL TRACE ELEMENT RESEARCH. 2021;199(10):3618-3624
Amyotrophic Lateral Sclerosis After Exposure to Manganese from Traditional Medicine Procedures in Kenya
Roos E; Warmlander SKTS; Meyer J; Sholts SB; Jarvet J; Graslund A; Roos PM
Article: ACTA BIOCHIMICA POLONICA. 2021;68(2):169-179
Lithium ions display weak interaction with amyloid-beta (Aβ) peptides and have minor effects on their aggregation
Berntsson E; Paul S; Vosough F; Sholts SB; Jarvet J; Roos PM; Barth A; Graslund A; Warmlander S
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2020;27(10):1913-1917
Interleukin-1 receptor antagonist, interleukin-2 receptor alpha subunit and amyotrophic lateral sclerosis
Yuan S; Roos PM; Larsson SC
Article: NEUROBIOLOGY OF AGING. 2020;87:140.e1-140.e3
Serum 25-hydroxyvitamin D in amyotrophic lateral sclerosis: mendelian randomization study
Larsson SC; Roos PM
Article: BIOMOLECULES. 2019;10(1):E44-44
Mercury and Alzheimer's Disease: Hg(II) Ions Display Specific Binding to the Amyloid-β Peptide and Hinder Its Fibrillization
Wallin C; Friedemann M; Sholts SB; Noormaegi A; Svantesson T; Jarvet J; Roos PM; Palumaa P; Graslund A; Waermlaender SKTS
Article: SCIENTIFIC REPORTS. 2017;7(1):14423
Alzheimer's disease and cigarette smoke components: effects of nicotine, PAHs, and Cd(II), Cr(III), Pb(II), Pb(IV) ions on amyloid-β peptide aggregation
Wallin C; Sholts SB; Osterlund N; Luo J; Jarvet J; Roos PM; Ilag L; Graslund A; Warmlander SKTS
Article: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2016;38:183-193
Characterization of Mn(II) ion binding to the amyloid-β peptide in Alzheimer's disease
Wallin C; Kulkarni YS; Abelein A; Jarvet J; Liao Q; Strodel B; Olsson L; Luo J; Abrahams JP; Sholts SB; Roos PM; Kamerlin SCL; Graslund A; Warmlander SKTS
Article: JOURNAL OF ALZHEIMERS DISEASE. 2016;54(3):971-982
Specific Binding of Cu(II) Ions to Amyloid-Beta Peptides Bound to Aggregation-Inhibiting Molecules or SDS Micelles Creates Complexes that Generate Radical Oxygen Species
Tiiman A; Luo J; Wallin C; Olsson L; Lindgren J; Jarvet J; Roose P; Sholts SB; Rahimipour S; Abrahams JP; Karlstrom AE; Graslund A; Warmlander SKTS
Article: BIOMETALS. 2016;29(5):827-839
Treatment strategies in Alzheimer's disease: a review with focus on selenium supplementation
Aaseth J; Alexander J; Bjorklund G; Hestad K; Dusek P; Roos PM; Alehagen U
Article: NEUROLOGY. 2016;86(24):2271-2277
Depression in amyotrophic lateral sclerosis
Roos E; Mariosa D; Ingre C; Lundholm C; Wirdefeldt K; Roos PM; Fang F
Article: BIOLOGICAL TRACE ELEMENT RESEARCH. 2013;151(2):159-170
Metal Concentrations in Cerebrospinal Fluid and Blood Plasma from Patients with Amyotrophic Lateral Sclerosis
Roos PM; Vesterberg O; Syversen T; Flaten TP; Nordberg M
Article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2012;111(2):126-132
Mercury in the Spinal Cord After Inhalation of Mercury
Roos PM; Dencker L
Article: EXPERIMENTAL BIOLOGY AND MEDICINE. 2012;237(7):803-810
Manganese in cerebrospinal fluid and blood plasma of patients with amyotrophic lateral sclerosis
Roos PM; Lierhagen S; Flaten TP; Syversen T; Vesterberg O; Nordberg M
Article: BRAIN RESEARCH. 2007;1174:136-142
Separation of proteins including metallothionein in cerebrospinal fluid by size exclusion HPLC and determination of trace elements by HR-ICP-MS
Gellein K; Roos PM; Evje L; Vesterberge O; Flaten TP; Nordberg M; Syversen T
Article: AMYOTROPHIC LATERAL SCLEROSIS. 2006;7(3):183-186
ALS: Cytokine profile in cerebrospinal fluid T-cell clones
Holmoy T; Roos PM; Kvale EO
Article: LUPUS. 2004;13(10):817-819
Respiratory arrest in systemic lupus erythematosus due to phrenic nerve neuropathy
Omdal R; Roos P; Wildhagen K; Gunnarsson R
Journal article: FEBS JOURNAL. 1980;108(1):279-283
ON THE MECHANISM OF ELEVATED PROSTAGLANDIN-E2 PRODUCTION IN 3T3 FIBROBLASTS TRANSFORMED BY POLYOMA-VIRUS
ROOS P; LINDGREN JA; HAMMARSTROM S
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All other publications

Preprint: RESEARCH SQUARE. 2023
Molecular interactions between silver ions (Ag+) and amyloid-β (Aβ) peptides: binding affinities and structural effects
Lakela AL; Berntsson E; Vosough F; Jarvet J; Paul S; Barth A; Gräslund A; Roos PM; Wärmländer SKTS
Review: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2023;78:127165
Metal concentrations in cerebrospinal fluid, blood, serum, plasma, hair, and nails in amyotrophic lateral sclerosis: A systematic review and meta-analysis
Kamalian A; Foroughmand I; Koski L; Darvish M; Saghazadeh A; Kamalian A; Razavi SZE; Abdi S; Dehgolan SR; Fotouhi A; Roos PM
Preprint: MEDRXIV. 2023
Occupational lead exposure in gasoline station forecourt attendants and other occupations in relation to ALS (amyotrophic lateral sclerosis) risk
Koski L; Tshoni UA; Olowoyo JO; Kobyana AS; Lion NG; Mugivhisa LL; Wärmländer SKTS; Roos PM
Preprint: MEDRXIV. 2023
Blood lead concentrations in exposed forecourt attendants and taxi drivers in parts of South Africa
Olowoyo JO; Tshoni UA; Kobyana AS; Lion GN; Mugivhisa LL; Koski L; Wärmländer SKTS; Roos PM
Preprint: BIORXIV. 2023
Characterization of uranyl (UO22+) ion binding to amyloid beta (Aβ) peptides: effects on Aβ structure and aggregation
Berntsson E; Vosough F; Noormägi A; Padari K; Asplund F; Gielnik M; Paul S; Jarvet J; Tõugu V; Roos PM; Kozak M; Gräslund A; Barth A; Pooga M; Palumaa P; Wärmländer SKTS
Letter: SCIENCE OF THE TOTAL ENVIRONMENT. 2023;859(Pt 2):160367
Comments on Letter to the Editor by Ph. D. Jussi Sipila regarding our paper "Geochemistry of multiple sclerosis in Finland "
Astrom ME; Roos PM
Review: BIOMOLECULES. 2022;12(5):714
Cerebral Iron Deposition in Neurodegeneration
Dusek P; Hofer T; Alexander J; Roos PM; Aaseth JO
Preprint: SSRN ELECTRONIC JOURNAL. 2022
Geochemistry of Multiple Sclerosis in Finland
Roos PM; Åström ME
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(22):12193
Metals in ALS TDP-43 Pathology
Koski L; Ronnevi C; Berntsson E; Warmlander SKTS; Roos PM
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(17):9461
Copper, Iron, Selenium and Lipo-Glycemic Dysmetabolism in Alzheimer's Disease
Aaseth J; Skalny AV; Roos PM; Alexander J; Aschner M; Tinkov AA
Preprint: BIORXIV. 2021
Lithium ions display weak interaction with amyloid-beta (Aβ) peptides and have minor effects on their aggregation
Berntsson E; Paul S; Vosough F; Sholts SB; Jarvet J; Roos PM; Barth A; Gräslund A; Wärmländer SKTS
Published conference paper: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2019;52:48-52
Ultraclean paired sampling for metal analysis in neurodegenerative disorders
Roos PM
Review: BIOMETALS. 2018;31(5):737-747
Prevention of progression in Parkinson's disease
Aaseth J; Dusek P; Roos PM
Conference publication: FEBS OPEN BIO. 2018;8:34
Metal chemistry in neurodegenerative disorders
Roos PM
Conference publication: BIOPHYSICAL JOURNAL. 2018;114(3):219A
Mercury and Alzheimers Disease: HG(II) Ions Display Specific Binding to the Amyloid-Beta Peptide and Modulate its Aggregation
Warmlander S; Wallin C; Sholts S; Roos P; Jarvet J; Graslund A
Book chapter: BIOMETALS IN NEURODEGENERATIVE DISEASES. 2017;p. 175-193
Chapter 10 Metals and Motor Neuron Disease
Roos PM
Review: CLINICAL EPIDEMIOLOGY. 2015;7:181-193
Risk factors for amyotrophic lateral sclerosis
Ingre C; Roos PM; Piehl F; Kamel F; Fang F
Published conference paper: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2015;31:183-187
Iron and copper in progressive demyelination - New lessons from Skogholt's disease
Aspli KT; Flaten TP; Roos PM; Holmoy T; Skogholt JH; Aaseth J
Published conference paper: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2015;31:193-203
The neurotoxicity of iron, copper and manganese in Parkinson's and Wilson's diseases
Dusek P; Roos PM; Litwin T; Schneider SA; Flaten TP; Aaseth J
Published conference paper: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2014;28(4):418-421
Osteoporosis in neurodegeneration
Roos PM
Doctoral thesis: 2013
Studies on metals in motor neuron disease
Roos P
Editorial comment: ACTA NEUROLOGICA SCANDINAVICA. 2011;124(3):215-217
Inclusion body myositis in Alzheimer's disease
Roos PM; Vesterberg O; Nordberg M
Letter: EUROPEAN NEUROLOGY. 2007;58(1):57-58
Slowly progressing amyotrophic lateral sclerosis caused by H46R SOD1 mutation
Holmoy T; Bjorgo K; Roos PM
Published conference paper: EXPERIMENTAL BIOLOGY AND MEDICINE. 2006;231(9):1481-1487
Metals in motor neuron diseases
Roos PM; Vesterberg O; Nordberg M
Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2004;11:190
Inclusion body myositis in dementia of Alzheimer type
Roos PM
Conference publication: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2002;199:S50-S51
Inclusion body myositis and Alzheimer
Roos PM
Book chapter: CHEMISTRY, BIOCHEMISTRY, AND PHARMACOLOGICAL ACTIVITY OF PROSTANOIDS. 1979;p. 221-232
BIOSYNTHESIS OF PROSTAGLANDINS AND THROMBOXANES
Hammarström S; Lindgren JÅ; Roos P
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Grants

The Kamprad family foundation for research

Employments

Affiliated to Research, Department of Clinical Neuroscience, Karolinska Institutet, 2024-2026
Affiliated to Research, Department of Clinical Neuroscience, Karolinska Institutet, 2024-2026

Degrees and Education

Docent, Environmental Medicine, Karolinska Institutet, 2025
Degree Of Doctor Of Philosophy, Institute of Environmental Medicine, Karolinska Institutet, 2013

News from KI

Events from KI

Presentations

Presentation (slides etc.): JOURNAL OF THE NEUROLOGICAL SCIENCES. 2023;:121072
Geochemistry of multiple sclerosis in Finland
Roos P