Pedro Luis Moura

Publications
Public outreach and news

Selected publications

Article: BLOOD NEOPLASIA. 2024;1(2):100011
Competition of dual <i>SF3B1</i> <sup>mt</sup> clones in MDS-RS is associated with distinct RNA mis-splicing in hematopoietic stem cells.
Moura PL; Nannya Y; Aliouat A; Hofman IJ; Mortera-Blanco T; Yoshizato T; Saiki R; Nakagawa MM; Creignou M; Björklund A-C; Walldin G; Barbosa I; Jansson M; Grasso F; Elvarsdottir EM; Woll PS; Jacobsen SEW; Ogawa S; Hellström-Lindberg E
Article: CANCER RESEARCH. 2024;84(2):211-225
Erythroid Differentiation Enhances RNA Mis-Splicing in SF3B1-Mutant Myelodysplastic Syndromes with Ring Sideroblasts
Moura PL; Mortera-Blanco T; Hofman IJ; Todisco G; Kretzschmar WW; Bjoerklund A-C; Creignou M; Hagemann-Jensen M; Ziegenhain C; Cabrerizo Granados D; Barbosa I; Walldin G; Jansson M; Ashley N; Mead AJ; Lundin V; Dimitriou M; Yoshizato T; Woll PS; Ogawa S; Sandberg R; Jacobsen SEW; Hellstrom-Lindberg E
Article: IMMUNOLOGY AND CELL BIOLOGY. 2023;101(10):947-963
Defining the proteomic landscape of cultured macrophages and their polarization continuum
Oates TCL; Moura PL; Cross S; Roberts K; Baum HE; Haydn-Smith KL; Wilson MC; Heesom KJ; Severn CE; Toye AM
Article: CLINICAL CANCER RESEARCH. 2023;29(20):4256-4267
Integrated Genomic and Transcriptomic Analysis Improves Disease Classification and Risk Stratification of MDS with Ring Sideroblasts
Todisco G; Creignou M; Bernard E; Bjorklund A-C; Moura PL; Tesi B; Mortera-Blanco T; Sander B; Jansson M; Walldin G; Barbosa I; Reinsbach SE; Hofman IJ; Nilsson C; Yoshizato T; Dimitriou M; Chang D; Olafsdottir S; Larsson SV; Tobiasson M; Malcovati L; Woll P; Jacobsen SEW; Papaemmanuil E; Hellstroem-Lindberg E
Letter: BLOOD ADVANCES. 2022;6(16):4705-4709
The extent of residual WT HSPCs is associated with the degree of anemia in patients with SF3B1-mutated MDS-RS
Hofman IJF; Mortera-Blanco T; Moura PL; Vestlund J; Larsson SV; Elvarsdottir EM; Walldin G; Tobiasson M; Sander B; Dimitriou M; Jacobsen S-EW; Woll PS; Jadersten M; Hellstrom-Lindberg E
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2020;190(4):E250-E255
Rapid diagnosis of hereditary haemolytic anaemias using automated rheoscopy and supervised machine learning
Moura PL; Dobbe JGG; Streekstra GJ; Rab MAE; Veldthuis M; Fermo E; van Wijk R; van Zwieten R; Bianchi P; Toye AM; Satchwell TJ
Letter: HAEMATOLOGICA. 2020;105(6):e268-e271
PIEZO1 gain-of-function mutations delay reticulocyte maturation in hereditary xerocytosis
Moura PL; Hawley BR; Dobbe JGG; Streekstra GJ; Rab MAE; Bianchi P; van Wijk R; Toye AM; Satchwell TJ
Article: BLOOD ADVANCES. 2019;3(17):2653-2663
Reticulocyte and red blood cell deformation triggers specific phosphorylation events
Moura PL; Iragorri MAL; Francais O; Le Pioufle B; Dobbe JGG; Streekstra GJ; El Nemer W; Toye AM; Satchwell TJ
Article: NATURE COMMUNICATIONS. 2019;10(1):3806
Genetic manipulation of cell line derived reticulocytes enables dissection of host malaria invasion requirements
Satchwell TJ; Wright KE; Haydn-Smith KL; Sanchez-Roman Teran F; Moura PL; Hawksworth J; Frayne J; Toye AM; Baum J
Article: HAEMATOLOGICA. 2018;103(12):1997-2007
Non-muscle myosin II drives vesicle loss during human reticulocyte maturation
Moura PL; Hawley BR; Mankelow TJ; Griffiths RE; Dobbe JGG; Streekstra GJ; Anstee DJ; Satchwell TJ; Toye AM

Articles

Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2024;33(5):580-587
Identification of biallelic POLA2 variants in two families with an autosomal recessive telomere biology disorder
Kvarnung M; Pettersson M; Chun-on P; Rafati M; Mcreynolds LJ; Norberg A; Moura PL; Pesonen I; Chaireti R; Soderholm BG; Burlin J; Ryden J; Lindberg EH; Giri N; Savage SA; Agarwal S; Nordgren A; Tesi B
Journal article: BLOOD. 2024;144:3198-3199
Large-Scale Transcriptome Analysis Supports Genomic Taxonomy and Predicts Response to Hypomethylating Agents in Myelodysplastic Neoplasms
Todisco G; Zampini M; Moura PL; Buizza A; Mortera-Blanco T; Tranberg A; Riva E; Creignou M; Campagna A; Ubezio M; Bjoerklund A-C; Tesi B; Barbosa I; Ventura D; Ficara F; Papaemmanuil E; Santoro A; Tobiasson M; Bernard E; Porta MGD; Lindberg EH
Article: BLOOD ADVANCES. 2024;8(19):5166-5178
Complete absence of GLUT1 does not impair human terminal erythroid differentiation
Freire CM; King NR; Dzieciatkowska M; Stephenson D; Moura PL; Dobbe JGG; Streekstra GJ; D'Alessandro A; Toye AM; Satchwell TJ
Article: JOURNAL OF INTERNAL MEDICINE. 2024;296(1):53-67
Early transfusion patterns improve the Molecular International Prognostic Scoring System (IPSS-M) prediction in myelodysplastic syndromes
Creignou M; Bernard E; Gasparini A; Tranberg A; Todisco G; Moura PL; Ejerblad E; Nilsson L; Garelius H; Antunovic P; Lorenz F; Rasmussen B; Walldin G; Mortera-Blanco T; Jansson M; Tobiasson M; Elena C; Ferrari J; Galli A; Pozzi S; Malcovati L; Edgren G; Crowther MJ; Jaedersten M; Papaemmanuil E; Hellstroem-Lindberg E
Article: JOURNAL OF TRANSLATIONAL MEDICINE. 2024;22(1):526
Neutrophils cultured ex vivo from CD34⁺ stem cells are immature and genetically tractable
Naveh CA; Roberts K; Zakrzewski P; Rice CM; Ponce-Garcia FM; Fleming K; Thompson M; Panyapiean N; Jiang H; Diezmann S; Moura PL; Toye AM; Amulic B
Journal article: HEMASPHERE. 2023;7(Suppl):e22964a1
P713: EXPLORING CLONAL COMPETITION THROUGH 12‐YEAR FOLLOW‐UP OF AN MDS‐RS PATIENT WITH DUAL SF3B1 MUTATIONS
Moura P; Hofman I; Nannya Y; Aliouat A; Mortera‐Blanco T; Yoshizato T; Saiki R; Nakagawa M; Björklund A; Walldin G; Barbosa I; Jansson M; Grasso F; Creignou M; Elvarsdottir E; Woll P; Jacobsen SE; Ogawa S; Lindberg EH
Journal article: LEUKEMIA RESEARCH. 2023;128:107119
EARLY TRANSFUSION PATTERNS PREDICT OUTCOMES INDEPENDENTLY OF IPSS-M SCORE IN MYELODYSPLASTIC SYNDROMES
Creignou M; Bernard E; Crowther M; Tranberg A; Todisco G; Moura P; Ejerblad E; Nilsson L; Garelius H; Antunovic P; Lorenz F; Rasmussen B; Walldin G; Mortera-Blanco T; Jansson M; Tobiasson M; Edgren G; Jadersten M; Papaemmanuil E; Hellstrom-Lindberg E
Journal article: LEUKEMIA RESEARCH. 2023;128:107135
ACCELERATED RNA SPLICING DYNAMICS DURING ERYTHROID DIFFERENTIATION AMPLIFY MIS-SPLICING IN SF3B1-MUTANT MDS-RS
Moura P; Mortera-Blanco T; Hofman I; Todisco G; Kretzschmar W; Bjorklund A-C; Creignou M; Hagemann-Jensen M; Ziegenhain C; Granados D; Barbosa I; Walldin G; Jansson M; Mead A; Lundin V; Dimitriou M; Yoshizato T; Woll P; Ogawa S; Sandberg R; Jacobsen SE; Hellstrom-Lindberg E
Article: VIRUSES-BASEL. 2023;15(2):445
I329L: A Dual Action Viral Antagonist of TLR Activation Encoded by the African Swine Fever Virus (ASFV)
Correia S; Moura PL; Ventura S; Leitao A; Parkhouse RME
Article: SEMINARS IN HEMATOLOGY. 2022;59(3):150-155
Clinical manifestations of clonal hematopoiesis: What has SF3B1-mutant MDS taught us?
Todisco G; Moura PL; Hellstrom-Lindberg E
Journal article: BLOOD. 2021;138:146
Integrative Analysis of Primary SF3B1 ^mt Ring Sideroblasts Provides Fundamental Insights into MDS-RS Pathogenesis and Dyserythropoiesis
Moura PL; Mortera-Blanco T; Hofman IJF; Todisco G; Kretzschmar WW; Barbosa I; Bjorklund A-C; Walldin G; Jansson M; Yoshizato T; Woll PS; Jacobsen SEW; Lindberg EH
Journal article: LEUKEMIA RESEARCH. 2021;108:106679.9
O13 Topic: AS01-Diagnosis/AS01c-Molecular aberrations (cytogenetic, genetic, gene expression) WHOLE TRANSCRIPTOME ANALYSIS IDENTIFIES DISTINCT GENE EXPRESSION PROFILES BETWEEN SF3B1MUT AND SF3B1WT MYELODYSPLASTIC SYNDROME WITH RING SIDEROBLASTS
Todisco G; Creignou M; Bernard E; Björklund A-C; Moura P; Jansson M; Barbosa I; Chang D; Venckute S; Walldin G; Tesi B; Mortera-Blanco T; Papaemmanuil E; Hellström-Lindberg E
Article: EJHAEM. 2021;2(2):175-187
Blood group type A secretors are associated with a higher risk of COVID-19 cardiovascular disease complications
Mankelow TJ; Singleton BK; Moura PL; Stevens-Hernandez CJ; Cogan NM; Gyorffy G; Kupzig S; Nichols L; Asby C; Pooley J; Ruffino G; Hosseini F; Moghaddas F; Attwood M; Noel A; Cooper A; Arnold DT; Hamilton F; Hyams C; Finn A; Toye AM; Anstee DJ
Article: ELIFE. 2017;6:e25605
Reciprocal analyses in zebrafish and medaka reveal that harnessing the mmune response promotes cardiac regeneration
Lai S-L; Marin-Juez R; Moura PL; Kuenne C; Lai JKH; Tsedeke AT; Guenther S; Looso M; Stainier DYR

All other publications

Letter: ANNALS OF INTERNAL MEDICINE. 2025;178(2):300-304
Germline UBA1 Variant With Somatic Amplification in a Woman With Inflammatory Diseases and Myelodysplastic Syndrome
Creignou M; Sirenko M; Moura PL; Mortera-Blanco T; Dimitriou M; Sander B; Domenico D; Ossa JEA; Tesi B; Beck DB; Woll P; Jacobsen S-EW; Papaemmanuil E; Bernard E; Hellstrom-Lindberg E
Preprint: BIORXIV. 2024;BIORXIV
Inflammatory Mesenchymal Stromal Cells and IFN-responsive T cells are key mediators of human bone marrow niche remodeling in CHIP and MDS.
Prummel KD; Woods K; Kholmatov M; Schmitt EC; Vlachou EP; Poschmann G; Stühler K; Wehner R; Schmitz M; Winter S; Oelschlaegel U; Schwartz LS; Moura PL; Hellström-Lindberg E; Theobald M; Trowbridge JJ; Platzbecker U; Zaugg JB; Guezguez B
Corrigendum: JOURNAL OF TRANSLATIONAL MEDICINE. 2024;22(1):899
Neutrophils cultured ex vivo from CD34 + stem cells are immature and genetically tractable (vol 22, 526, 2024)
Naveh CA; Roberts K; Zakrzewski P; Rice CM; Ponce-Garcia FM; Fleming K; Thompson M; Panyapiean N; Jiang H; Diezmann S; Moura PL; Toye AM; Amulic B
Preprint: BIORXIV. 2024
SF3B1-mutant mis-splicing ofUBA1confers a targetable therapeutic vulnerability through UBA1 inhibition
Thier J; Hofmann S; Kirchhof K; Todisco G; Mortera-Blanco T; Barbosa I; Björklund A-C; Deslauriers A; Papaemmanuil E; Papapetrou E; Hellström-Lindberg E; Moura P; Lundin V
Preprint: BIORXIV. 2024;BIORXIV
Complete absence of GLUT1 does not impair human terminal erythroid differentiation.
Freire CM; King NR; Dzieciatkowska M; Stephenson D; Moura PL; Dobbe JGG; Streekstra GJ; D'Alessandro A; Toye AM; Satchwell TJ
Preprint: MEDRXIV. 2023
Neutrophils culturedex vivofrom CD34⁺stem cells are immature and genetically tractable
Naveh C; Roberts K; Rice C; Fleming K; Thompson M; Panyapiean N; Diezmann S; Moura P; Toye A; Amulic B
Preprint: BIORXIV. 2023
Erythroid differentiation intensifies RNA mis-splicing inSF3B1-mutant myelodysplastic syndromes with ring sideroblasts
Moura P; Mortera-Blanco T; Hofman IJF; Todisco G; Kretzschmar W; Björklund A-C; Creignou M; Hagemann-Jensen M; Ziegenhain C; Granados D; Barbosa I; Walldin G; Jansson M; Ashley N; Mead A; Lundin V; Dimitriou M; Yoshizato T; Woll P; Ogawa S; Sandberg R; Jacobsen SE; Hellström-Lindberg E
Conference publication: BLOOD. 2022;140:6898-6899
Long-Term Clonal Inversion in an MDS-RS Case with Dual SF3B1 Mutations
Moura PL; Hofman IJF; Nannya Y; Aliouat A; Mortera-Blanco T; Yoshizato T; Saiki R; Nakagawa MM; Bjorklund A-C; Walldin G; Barbosa I; Jansson M; Grasso F; Creignou M; Elvarsdottir EM; Woll PS; Jacobsen SEW; Ogawa S; Hellstrom-Lindberg E
Preprint: BIORXIV. 2022
Characterizing the polarization continuum of macrophage subtypes M1, M2a and M2c
Oates T; Moura P; Cross S; Roberts K; Baum H; Haydn-Smith K; Wilson M; Heesom K; Severn C; Toye A
Meeting abstract: BLOOD. 2021;138:3695
Whole Transcriptome Analysis Identifies Distinct Gene Expression Profiles between SF3B1mut and SF3B1 wt Myelodysplastic Syndrome with Ring Sideroblasts
Todisco G; Creignou M; Bernard E; Björklund A-C; Moura PL; Jansson M; Chang D; Venckute S; Walldin G; Malcovati L; Tesi B; Mortera-Blanco T; Barbosa I; Papaemmanuil E; Lindberg EH
Conference publication: LEUKEMIA RESEARCH. 2021;108:S10-S11
WHOLE TRANSCRIPTOME ANALYSIS IDENTIFIES DISTINCT GENE EXPRESSION PROFILES BETWEEN SF3B1MUT AND SF3B1WT MYELODYSPLASTIC SYNDROME WITH RING SIDEROBLASTS
Todisco G; Creignou M; Bernard E; Bjorklund A-C; Moura P; Jansson M; Barbosa I; Chang D; Venckute S; Walldin G; Tesi B; Mortera-Blanco T; Papaemmanuil E; Hellstrom-Lindberg E
Preprint: MEDRXIV. 2020
Blood group A Secretors are associated with a higher risk of COVID-19 cardiovascular disease complications
Mankelow T; Singleton B; Moura P; Stevens-Hernandez C; Cogan N; Gyorffy G; Kupzig S; Nichols L; Asby C; Pooley J; Ruffino G; Hosseini F; Moghaddas F; Attwood M; Noel A; Cooper A; Arnold D; Hamilton F; Hyams C; Finn A; Toye A; Anstee D

Selected publications

Articles

All other publications

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