Päivi Östling
Principal Researcher
E-mail: paivi.ostling@ki.se
Telephone: +46852482304
Visiting address: SciLifeLab, Tomtebodavägen 23a, 17121 Solna
Postal address: K7 Onkologi-Patologi, K7 Forskning Kallioniemi Östling, 171 77 Stockholm
About me
- I am a biochemist by training, now focusing on precision medicine research
and implementation. My motivation lies in my deep wish to safely implement
our technological advances to benefit patients.
Päivi Östling has more than 10 years of research experience in the field of
precision cancer medicine (PCM) research. As of 2016, she has been
responsible for establishing a functional precision medicin (fPM) platform at
SciLifeLab through the Olli Kallioniemi research group where she also acts as
a co-principal investigator. The groups research focuses on individualized
drug profiling including multi-omics in acute myeloid leukemia, ovarian and
bladder cancer as well as pediatric tumors. She is active within the PCM
program of KI and since June 2021, she is one of the Scientific Leads of
Precision Medicine at SciLifeLab.
2023 National infrastructure to support clinical trials in precision
medicine with cutting edge technologies, Vetenskapsrådet
2022 Testing and Experimenting Facility Health
(TEF-Health) DIGITAL-2022-CLOUD-AI-02
2022 Building a sustainable European Innovation platform to enhance the
repurposing of medicine for all - Remedi4all Horizon Europe, Research and
Innovation Actions. PI of demonstrator project on " Validation drugs and
combinations for novel host targets in SARS-Cov-2 infection used to build the
platform"
2022 Radiumhemmets forskningsfonder ”Individualied therapy selection for
muscle invasive bladder cancer”
2021 Knut and Alice Wallenberg Foundation SciLifeLab National Covid-19
Research Program: AI-driven drug and target prioritization for Covid-19 in
collaboration with Charlotte Stadler, Emma Lundberg and Ola Spjuth
2021 Vinnova testbed grant: Precision care bringing technology innovation
into oncology (PRIO), PI: Janne Lehtiö
2021 Miltons donationsfond grant: Spatial single cell maps of bladder cancer
microenvironment - implications for prognosis and treatment
2020 Knut and Alice Wallenberg Foundation SciLifeLab National Covid-19
Research Program: Spatial single-cell mapping of SARS-Cov2 interacting host
proteins for quick and targeted drug repurposing PI: Charlotte Stadler
2019 Lillian Sagen och Curt Ericssons fond: A roadmap to a clinical testbed
for precision cancer medicine
2018 Vinnova challenge-driven innovation, stage 2: Nanoscale drug testing:
Sweden as a testbed for revolutionizing drug discovery PI: Olli Kallioniemi,
project lead Brinton Seashore-Ludlow
2016 Associate Professor in Biochemical Systems Biology, Faculty of Science
and Engineering, Åbo Akademi University, Finland
2006 - 2011 Postdoctoral training, Medical Biotechnology, VTT, Finland
2006 PhD Turku Centre for Biotechnology, Åbo Akademi University, Finland
1999 MSc Biochemistry, Faculty of Biochemistry and Pharmacy, Åbo Akademi
University, Finland
Research
- My research is on precision cancer medicine in bladder cancer. The aim is to
link spatial tissue maps with drug sensitivity and molecular profiles to
understand treatment responses.
Articles
- Journal article: BLOOD. 2024;144(Supplement 1):1565
- Article: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH. 2024;43(1):107
- Journal article: CANCER RESEARCH. 2024;84(6_Supplement):7517
- Journal article: CANCER RESEARCH. 2024;84(6_Supplement):3100
- Journal article: CANCER RESEARCH. 2024;84(6):706
- Journal article: CANCER RESEARCH. 2024;84(6_Supplement):4727
- Article: NPJ PRECISION ONCOLOGY. 2024;8(1):38
- Article: MOLECULAR ONCOLOGY. 2024;18(2):317-335
- Article: NPJ PRECISION ONCOLOGY. 2023;7(1):111
- Article: NUCLEIC ACIDS RESEARCH. 2023;51(W1):W57-W61
- Journal article: CANCER RESEARCH. 2023;83(7):6612
- Article: NPJ PRECISION ONCOLOGY. 2023;7(1):32
- Journal article: IMMUNO-ONCOLOGY AND TECHNOLOGY. 2022;16:100328
- Article: JOURNAL OF INTERNAL MEDICINE. 2022;292(6):925-940
- Article: CELL REPORTS: METHODS. 2022;2(7):100256
- Journal article: HEMASPHERE. 2022;6:442-443
- Journal article: CANCER RESEARCH. 2022;82(12_Supplement):1890
- Article: NATURE COMMUNICATIONS. 2022;13(1):1691
- Article: NATURE CANCER. 2022;3(2):251-261
- Article: CANCER RESEARCH. 2021;81(22):5733-5744
- Article: AMERICAN JOURNAL OF HEMATOLOGY. 2021;96(5):580-588
- Article: BIOINFORMATICS. 2020;36(11):3602-3604
- Article: JOURNAL OF PATHOLOGY. 2020;250(2):159-169
- Article: CELL DEATH AND DIFFERENTIATION. 2019;26(12):2577-2593
- Article: INTERNATIONAL JOURNAL OF CANCER. 2019;144(6):1356-1366
- Article: BRITISH JOURNAL OF CANCER. 2019;120(4):435-443
- Journal article: CANCER RESEARCH. 2018;78(13_Supplement):5302
- Journal article: ANNALS OF ONCOLOGY. 2017;28:vii2
- Journal article: CANCER RESEARCH. 2017;77(13_Supplement):5732
- Journal article: CANCER RESEARCH. 2017;77(13_Supplement):3854
- Journal article: CANCER RESEARCH. 2017;77(13_Supplement):4207
- Journal article: CANCER RESEARCH. 2017;77(13_Supplement):3838
- Article: EUROPEAN UROLOGY. 2017;71(3):319-327
- Journal article: EUROPEAN JOURNAL OF CANCER. 2016;69:s80
- Article: NATURE REVIEWS DRUG DISCOVERY. 2016;15(11):751-769
- Article: SCIENTIFIC REPORTS. 2016;6:32412
- Journal article: CANCER RESEARCH. 2016;76(14_Supplement):608
- Article: EUROPEAN UROLOGY. 2016;69(6):1120-1128
- Journal article: CLINICAL CANCER RESEARCH. 2016;22(2_Supplement):pr17
- Article: BIOINFORMATICS. 2015;31(23):3815-3821
- Article: EUROPEAN UROLOGY. 2015;68(4):581-588
- Article: MOLECULAR ONCOLOGY. 2015;9(7):1287-1300
- Article: INTERNATIONAL JOURNAL OF CANCER. 2015;136(11):2535-2545
- Journal article: CANCER RESEARCH. 2014;74(19_Supplement):4184
- Journal article: EUROPEAN JOURNAL OF CANCER. 2014;50:s164
- Article: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING. 2014;17(4):377-386
- Article: ONCOGENE. 2013;32(41):4892-4902
- Journal article: CANCER RESEARCH. 2013;73(8_Supplement):5273
- Journal article: CANCER RESEARCH. 2013;73(8_Supplement):4170
- Article: MOLECULAR & CELLULAR PROTEOMICS. 2011;10(7):m110.005322
- Article: CANCER RESEARCH. 2011;71(5):1956-1967
- Article: ONCOGENE. 2009;28(44):3926-3936
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2007;282(10):7077-7086
- Article: GENES & DEVELOPMENT. 2006;20(7):836-847
- Article: CELL STRESS & CHAPERONES. 2001;6(4):377-385
- Article: FASEB JOURNAL. 1999;13(9):1089-1098
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All other publications
- Preprint: BIORXIV. 2024
- Preprint: BIORXIV. 2024
- Review: JOURNAL OF INTERNAL MEDICINE. 2023;294(4):413-436
- Conference publication: 2023
- Preprint: RESEARCH SQUARE. 2023
- Meeting abstract: CANCER RESEARCH. 2023;83(7):4578
- Conference publication: BLOOD. 2022;140:6299
- Conference publication: BLOOD. 2022;140:6290
- Review: JOURNAL OF INTERNAL MEDICINE. 2022;292(2):243-261
- Corrigendum: NATURE CANCER. 2022;3(5):649
- Conference publication: CANCER RESEARCH. 2022;82(12)
- Preprint: RESEARCH SQUARE. 2021
- Letter: NATURE MEDICINE. 2020;26(7):992-994
- Meeting abstract: BLOOD. 2019;134:4641
- Conference publication: CANCER RESEARCH. 2018;78(13):2199
- Conference publication: ANNALS OF ONCOLOGY. 2017;28
- Letter: NATURE. 2016;540(7631):E5-E6
- Conference publication: EUROPEAN JOURNAL OF CANCER. 2014;50:S64
- Meeting abstract: CANCER RESEARCH. 2011;71:3977
- Meeting abstract: EUROPEAN JOURNAL OF CANCER, SUPPLEMENT. 2010;8(7):177
- Meeting abstract: CANCER RESEARCH. 2010;70:2072
- Meeting abstract: CANCER RESEARCH. 2010;70:1953
- Review: FASEB JOURNAL. 2001;15(7):1118-1131
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