Otto Bergman

Publications
CV
Public outreach and news

Articles

Article: VASCULAR PHARMACOLOGY. 2025;159:107490
PCSK6 ablation in blood circulating cells increases atherosclerotic burden, but improves plaque stability by activating Th17-smooth muscle cell modulatory axis
Suur BE; Karadimou G; Willems CJJM; Bergman O; Lengquist M; Kronqvist M; Baumgartner R; Malin S; Gistera A; Hansson GK; Malarstig A; Hedin U; Ketelhuth DFJ; Matic L
Article: EUROPEAN HEART JOURNAL. 2025;46(3):308-322
Atheroma transcriptomics identifies ARNTL as a smooth muscle cell regulator and with clinical and genetic data improves risk stratification
Narayanan S; Vuckovic S; Bergman O; Wirka R; Verdezoto Mosquera J; Chen QS; Baldassarre D; Tremoli E; Veglia F; Lengquist M; Aherrahrou R; Razuvaev A; Gigante B; Bjoerck HM; Miller CL; Quertermous T; Hedin U; Matic L
Article: JVS - VASCULAR SCIENCE. 2025;6:100280
Atherosclerotic plaque instability in symptomatic non-significant carotid stenoses
Cyreus P; Waden K; Hellberg S; Bergman O; Lengquist M; Buckler A; Karlof E; Matic L; Roy J; Marlevi D; Chemaly M; Hedin U
Article: JOURNAL OF INTERNAL MEDICINE. 2025;297(1):47-59
Statin-associated regulation of hepatic PNPLA3 in patients without known liver disease
Ahmed O; Shavva VS; Tarnawski L; Dai W; Borg F; Olofsson VV; Liu T; Saliba-Gustafsson P; Simini C; Pedrelli M; Bergman O; Norata GD; Parini P; Franco-Cereceda A; Eriksson P; Malin SG; Bjorck HM; Olofsson PS
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2024;44(3):666-689
Regulation of YAP Promotor Accessibility in Endothelial Mechanotransduction
Mannion AJ; Zhao H; Zhang Y; von Wright Y; Bergman O; Roy J; Saharinen P; Holmgren L
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2023;101(10):1323-1333
SPP1/osteopontin: a driver of fibrosis and inflammation in degenerative ascending aortic aneurysm?
Freiholtz D; Bergman O; Pradhananga S; Lang K; Poujade F-A; Granath C; Olsson C; Franco-Cereceda A; Sahlen P; Eriksson P; Bjorck HM
Article: NATURE CARDIOVASCULAR RESEARCH. 2023;2(7):629-644
The VE-cadherin/AmotL2 mechanosensory pathway suppresses aortic inflammation and the formation of abdominal aortic aneurysms
Zhang Y; Zhang Y; Hutterer E; Hultin S; Bergman O; Kolbeinsdottir S; Jin H; Forteza MJ; Ketelhuth DFJ; Roy J; Hedin U; Enge M; Matic L; Eriksson P; Holmgren L
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2023;101(7):801-811
Bicuspid aortic valve aortopathy is characterized by embryonic epithelial to mesenchymal transition and endothelial instability
Freiholtz D; Bergman O; Lang K; Poujade F-A; Paloschi V; Granath C; Lindeman JHN; Olsson C; Franco-Cereceda A; Eriksson P; Bjorck HM
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2022;42(5):659-676
Plaque Evaluation by Ultrasound and Transcriptomics Reveals BCLAF1 as a Regulator of Smooth Muscle Cell Lipid Transdifferentiation in Atherosclerosis
Rykaczewska U; Zhao Q; Saliba-Gustafsson P; Lengquist M; Kronqvist M; Bergman O; Huang Z; Lund K; Waden K; Pons Vila Z; Caidahl K; Skogsberg J; Vukojevic V; Lindeman JHN; Roy J; Hansson GK; Treuter E; Leeper NJ; Eriksson P; Ehrenborg E; Razuvaev A; Hedin U; Matic L
Article: FRONTIERS IN PHARMACOLOGY. 2022;13:988561
Therapeutic potential of the Proprotein Convertase Subtilisin/Kexin family in vascular disease
Suur BE; Chemaly M; Liljeqvist ML; Djordjevic D; Stenemo M; Bergman O; Karlof E; Lengquist M; Odeberg J; Hurt-Camejo E; Eriksson P; Ketelhuth DFJ; Roy J; Hedin U; Nyberg M; Matic L
Article: COMMUNICATIONS BIOLOGY. 2021;4(1):1109
Prenylcysteine oxidase 1, an emerging player in atherosclerosis
Banfi C; Baetta R; Barbieri SS; Brioschi M; Guarino A; Ghilardi S; Sandrini L; Eligini S; Polvani G; Bergman O; Eriksson P; Tremoli E
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;147(5):1742-1752
Chromatin interactions in differentiating keratinocytes reveal novel atopic dermatitis- and psoriasis-associated genes
Sahlen P; Spalinskas R; Asad S; Das Mahapatra K; Hojer P; Anil A; Eisfeldt J; Srivastava A; Nikamo P; Mukherjee A; Kim K-H; Bergman O; Stahle M; Sonkoly E; Pivarcsi A; Wahlgren C-F; Nordenskjold M; Taylan F; Bradley M; Tapia-Paez I
Article: INTERNATIONAL JOURNAL OF OBESITY. 2020;44(2):377-387
Prospective analyses of white adipose tissue gene expression in relation to long-term body weight changes
Kwok KHM; Ryden M; Andersson DP; Beauchef G; Guere C; Vie K; Bergman O; Lundback V; Arner P; Dahlman I
Article: JVS - VASCULAR SCIENCE. 2020;1:13-27
Transcriptomic profiling of experimental arterial injury reveals new mechanisms and temporal dynamics in vascular healing response
Rohl S; Rykaczewska U; Seime T; Suur BE; Diez MG; Gadin JR; Gainullina A; Sergushichev AA; Wirka R; Lengquist M; Kronqvist M; Bergman O; Odeberg J; Lindeman JHN; Quertermous T; Hamsten A; Eriksson P; Hedin U; Razuvaev A; Matic LP
Article: EUROPEAN HEART JOURNAL. 2019;40(30):2495-2503
Prevention of radiotherapy-induced arterial inflammation by interleukin-1 blockade
Christersdottir T; Pirault J; Gistera A; Bergman O; Gallina AL; Baumgartner R; Lundberg AM; Eriksson P; Yan Z-Q; Paulsson-Berne G; Hansson GK; Olofsson PS; Halle M
Article: JOURNAL OF INTERNAL MEDICINE. 2019;285(1):102-114
The mir-200 family regulates key pathogenic events in ascending aortas of individuals with bicuspid aortic valves
Maleki S; Cottrill KA; Poujade F-A; Bhattachariya A; Bergman O; Gadin JR; Simon N; Lundstromer K; Franco-Cereceda A; Bjorck HM; Chan SY; Eriksson P
Article: SCIENTIFIC REPORTS. 2018;8(1):2777
Altered DNA methylation indicates an oscillatory flow mediated epithelial-to-mesenchymal transition signature in ascending aorta of patients with bicuspid aortic valve
Bjorck HM; Du L; Pulignani S; Paloschi V; Lundstromer K; Kostina AS; Osterholm C; Malashicheva A; Kostareva A; Evangelista A; Teixido-Tura G; Maleki S; Franco-Cereceda A; Eriksson P
Article: KIDNEY INTERNATIONAL REPORTS. 2017;2(6):1208-1218
Altered Protein Composition of Subcutaneous Adipose Tissue in Chronic Kidney Disease
Gertow J; Ng CZ; Branca RMM; Werngren O; Du L; Kjellqvist S; Hemmingsson P; Bruchfeld A; MacLaughlin H; Eriksson P; Axelsson J; Fisher RM
Article: SCIENTIFIC REPORTS. 2016;6:35712
Mesenchymal state of intimal cells may explain higher propensity to ascending aortic aneurysm in bicuspid aortic valves
Maleki S; Kjellqvist S; Paloschi V; Magne J; Branca RMM; Du L; Hultenby K; Petrini J; Fuxe J; Lehtio J; Franco-Cereceda A; Eriksson P; Bjorck HM
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2015;35(4):973-980
Aneurysm Development in Patients With a Bicuspid Aortic Valve Is Not Associated With Transforming Growth Factor-β Activation
Paloschi V; Gadin JR; Khan S; Bjorck HM; Du L; Maleki S; Roy J; Lindeman JHM; Mohamed SA; Tsuda T; Franco-Cereceda A; Eriksson P
Article: TREE PHYSIOLOGY. 2014;34(11):1240-1251
Condensed tannin biosynthesis and polymerization synergistically condition carbon use, defense, sink strength and growth in Populus.
Harding SA; Xue L-J; Du L; Nyamdari B; Lindroth RL; Sykes R; Davis MF; Tsai C-J
Article: NUCLEIC ACIDS RESEARCH. 2011;39(3):825-836
MiRNA-miRNA synergistic network: construction via co-regulating functional modules and disease miRNA topological features
Xu J; Li C-X; Li Y-S; Lv J-Y; Ma Y; Shao T-T; Xu L-D; Wang Y-Y; Du L; Zhang Y-P; Jiang W; Li C-Q; Xiao Y; Li X
Article: OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY. 2011;15(1-2):25-35
Functional homogeneity in microRNA target heterogeneity--a new sight into human microRNomics.
Wang Y; Du L; Li X; Zhang S; Xiao Y; Gong B; Wang Q; Zhou M; Xu C; Chen X; Lv S; Rao S
Article: BMC SYSTEMS BIOLOGY. 2008;2:72
Constructing disease-specific gene networks using pair-wise relevance metric: Application to colon cancer identifies interleukin 8, desmin and enolase 1 as the central elements
Jiang W; Li X; Rao S; Wang L; Du L; Li C; Wu C; Wang H; Wang Y; Yang B
Article: GENE. 2008;408(1-2):104-111
A systematic method for mapping multiple loci: An application to construct a genetic network for rheumatoid arthritis
Li C; Zhang G; Li X; Rao S; Gong B; Jiang W; Hao D; Wu P; Wu C; Du L; Xiao Y; Wang Y
Article: BMC BIOINFORMATICS. 2006;7:26
Discovery of time-delayed gene regulatory networks based on temporal gene expression profiling
Li X; Rao SQ; Jiang W; Li CX; Xiao Y; Guo Z; Zhang QP; Wang LH; Du L; Li J; Li L; Zhang TW; Wang QK
Article: GENOMICS. 2005;85(1):16-23
A robust hybrid between genetic algorithm and support vector machine for extracting an optimal feature gene subset.
Li L; Jiang W; Li X; Moser KL; Guo Z; Du L; Wang Q; Topol EJ; Wang Q; Rao S
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All other publications

Review: FRONTIERS IN CARDIOVASCULAR MEDICINE. 2019;6:182
Endothelial/Epithelial Mesenchymal Transition in Ascending Aortas of Patients With Bicuspid Aortic Valve
Maleki S; Poujade F-A; Bergman O; Gadin JR; Simon N; Lang K; Franco-Cereceda A; Body SC; Bjorck HM; Eriksson P
Published conference paper: LECTURE NOTES IN COMPUTER SCIENCE. 2006;4115:747-756
A novel method for expanding current annotations in gene ontology
Hao D; Li X; Du L; Xu L; Xu J; Rao S
Published conference paper: LECTURE NOTES IN COMPUTER SCIENCE. 2006;4115:774-779
Analysis of sib-pair IBD profiles using ensemble decision tree approach: Application to alcoholism
Jiang Y; Zhang Q; Li X; Du L; Jiang W; Zhang R; Li J; Rao S
Published conference paper: LECTURE NOTES IN COMPUTER SCIENCE. 2006;4115:768-773
An analysis of gene expression relationships between periodically expressed genes in the Hela cells
Xiao Y; Li X; Rao S; Wang J; Zhang Y; Du L
Published conference paper: LECTURE NOTES IN COMPUTER SCIENCE. 2005;3614:845-851
Analysis of sib-pair IBD profiles and genomic context for identification of the relevant molecular signatures for alcoholism
Li CX; Du L; Li X; Gong BS; Zhang J; Rao SQ
Published conference paper: LECTURE NOTES IN COMPUTER SCIENCE. 2005;3614:1184-1189
Large-scale ensemble decision analysis of sib-pair IBD profiles for identification of the relevant molecular signatures for alcoholism
Li X; Rao SQ; Zhang W; Zheng G; Jiang W; Du L

Employments

Senior Research Infrastructure Specialist, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2025-
Research Specialist, Department of Medicine, Karolinska Institutet, 2022-

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