Nick Tobin
Lecturer | Principal Researcher | Docent
E-mail: nick.tobin@ki.se
Visiting address: D2:04 GKS,Anna Steckséns gata 30A, 17176 Solna
Postal address: K7 Onkologi-Patologi, K7 Administration, 171 77 Stockholm
About me
- Principal Researcher and Team Leader with a Docent in Bioinformatics
working at the Department of Oncology-Pathology in BioClinicum
I completed my BSc in Biotechnology in 2004 at Dublin City University,
Ireland, where I also successfully defended my dissertation 4 years later in
the subject area of vascular biology. Since then I have held post-doctoral
positions in Malmö - at the Centre for Molcular Pathology, a part of Lund
University - Manchester - at the Paterson Institute for Cancer Research
- and
at Karolinkska Institutuet , Onk-Pat, all in the subject area of breast
cancer.
Research
- Our work involves the integration of multiple high-throughput data types
including next generation sequncing, SNP and gene expression arrays with
clinico-pathological information in order to perform high quality
translational research with a breast and pan-cancer focus. Specifically we
are interested in:
* Determining the added prognostic or treatment predictive value of
molecular biomarkers (including gene expression signatures) beyond that
provided by routine clinical diagnostics
* Understanding cell-cycle biology from a pan-cancer 'omics data
perspective
Teaching
- I mainly teach in the subject area of Bioinformatics, but also run seminars
on various aspects of cancer including its hallmarks and the utility of
cancer gene expression signatures in a clinical setting. Of note I:
* Have partcipated in over 12 weeks full-time pedagogic training courses
* Have completed over 500 hours teaching undergradates (BSc),
post-graduates (MSc and PhD) and medical professionals (MD) in both
hands-on demonstration and lecturing roles
* Executive board member FoTO - The Doctoral Programme in Tumour Biology and
Oncology [Jan. 2020 - present]
* Am responsible (Kursansvarig) for the Molecular Medicine-Oncology course
(15 credits), a part of the Biomedicine program [June 2020 - present]
* Director of Education (GUA) at Onk-Pat [Jan. 2021 - present]
* Chair for the Scientific Committee of the Cancer Core Europe translational
research Summer School [Jan. 2023 - present]
Articles
- Article: JOURNAL OF EXPERIMENTAL AND CLINICAL CANCER RESEARCH. 2024;43(1):107
- Article: BREAST CANCER RESEARCH. 2024;26(1):38
- Article: JOURNAL OF CLINICAL ONCOLOGY. 2022;40(35):4071-4082
- Article: NPJ PRECISION ONCOLOGY. 2022;6(1):59
- Article: INTERNATIONAL JOURNAL OF CANCER. 2022;150(12):2072-2082
- Article: PLOS COMPUTATIONAL BIOLOGY. 2022;18(3):e1010020
- Article: EUROPEAN JOURNAL OF CANCER. 2022;162:194-205
- Article: GENETICS IN MEDICINE. 2022;24(1):157-169
- Article: CELL REPORTS. 2021;36(8):109616
- Article: CANCERS. 2021;13(5):1175
- Article: INTERNATIONAL JOURNAL OF CANCER. 2021;148(4):884-894
- Article: ONCOGENE. 2020;39(32):5430-5440
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2020;130(3):1185-1198
- Article: GLIA. 2020;68(2):316-327
- Article: CANCERS. 2019;11(10):E1479-1479
- Article: EBIOMEDICINE. 2019;48:212-223
- Article: JAMA ONCOLOGY. 2019;5(9):1304-1309
- Article: JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2019;111(9):983-995
- Article: CANCER IMMUNOLOGY, IMMUNOTHERAPY. 2019;68(6):927-936
- Article: BREAST CANCER RESEARCH. 2019;21(1):36
- Article: BREAST CANCER RESEARCH. 2019;21(1):34
- Article: JOURNAL OF CLINICAL PATHOLOGY. 2018;71(9):787-794
- Article: BRITISH JOURNAL OF CANCER. 2018;118(4):480-488
- Article: CLINICAL CANCER RESEARCH. 2017;23(24):7512-7520
- Article: CLINICAL CANCER RESEARCH. 2017;23(23):7225-7231
- Article: JAMA ONCOLOGY. 2017;3(11):1503-1510
- Article: EUROPEAN JOURNAL OF CANCER. 2017;84:278-289
- Article: CLINICAL CANCER RESEARCH. 2017;23(10):2584-2592
- Article: SCIENTIFIC REPORTS. 2017;7(1):1089
- Article: THE JOURNAL OF PATHOLOGY: CLINICAL RESEARCH. 2017;3(1):38-43
- Article: CANCER RESEARCH. 2016;76(11):3166-3178
- Article: CLINICAL CANCER RESEARCH. 2016;22(10):2417-2426
- Article: MODERN PATHOLOGY. 2016;29(4):318-329
- Article: MOLECULAR ONCOLOGY. 2016;10(4):517-525
- Article: ONCOTARGET. 2015;6(32):33306-33318
- Article: JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2015;107(10):djv209
- Article: ANNALS OF ONCOLOGY. 2015;26(1):81-88
- Article: MOLECULAR ONCOLOGY. 2014;8(3):741-752
- Article: BMC CANCER. 2013;13:473
- Article: AMERICAN JOURNAL OF PATHOLOGY. 2013;182(6):2037-2047
- Article: HUMAN PATHOLOGY. 2012;43(11):2053-2061
- Article: CURRENT BREAST CANCER REPORTS. 2012;4(3):171-173
- Article: BMC CANCER. 2011;11:417
- Article: JOURNAL OF MOLECULAR DIAGNOSTICS. 2011;13(3):340-351
- Article: AMERICAN JOURNAL OF PATHOLOGY. 2010;177(6):2886-2897
- Article: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND CELL BIOLOGY. 2009;41(11):2287-2294
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. 2008;295(4):H1403-H1413
- Show more
All other publications
- Letter: CANCER COMMUNICATIONS. 2023;43(7):855-859
- Corrigendum: JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2016;108(3):djv434
- Review: JOURNAL OF INTERNAL MEDICINE. 2015;278(6):545-570
- Corrigendum: MOLECULAR ONCOLOGY. 2014;8(6):1159
Employments
- Principal Researcher, Department of Oncology-Pathology, Karolinska Institutet, 2022-
- Lecturer, Department of Oncology-Pathology, Karolinska Institutet, 2021-
Degrees and Education
- Docent, Karolinska Institutet, 2018