Mtakai Ngara

Mtakai Ngara

Postdoctoral Researcher
Visiting address: Solnavägen 9, Biomedicum, 17165 Solna
Postal address: C1 Mikrobiologi, tumör- och cellbiologi, C1 P & CF Nylén Kaneko, 171 77 Stockholm

Research

  • Every cell is unique and generates distinct molecular response(s) in disease.
    Understanding these perturbations at single cell resolution is critical in
    unravelling complex, yet important diseases such as malaria.
    In areas of endemic malaria transmission, individuals living in
    geographically defined regions often present distinct phenotypes when
    infected by the Plasmodium falciparum. I am interested in applying a systems
    approach to understanding how immune cells define the three key outcomes of
    malaria infection namely: asymptomatic, mild and symptomatic. To this end, we
    will adopt single cell RNA-seq and other genome-wide technologies to profile
    T lymphocytes derived from a high-resolution longitudinal cohort from Lake
    Victoria islands in Kenya. This will provide an opportunity to gain novel
    insight(s) into the disease in field transmission context and enhance our
    understanding of the main drivers of adaptive response to malaria infection.

Articles

All other publications

Employments

  • Postdoctoral Researcher, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2022-2025

Degrees and Education

  • Degree Of Doctor Of Philosophy, Department of Cell and Molecular Biology, Karolinska Institutet, 2019

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