Mona-Lisa Malarte

Mona-Lisa Malarte

Affiliated to Research
Visiting address: Blickagången 16, 14152 Huddinge
Postal address: H1 Neurobiologi, vårdvetenskap och samhälle, H1 Klinisk geriatrik Westman, 171 77 Stockholm
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About me

  • I did my bachelor's in Animal physiology and Neuroscience as a combined
    program in France and Canada. I completed my master's in Neuroscience in
    France at the University of Montpellier. During my master's, I did my thesis
    work in the group of Pr.Agneta Nordberg.

Research

  • The focus of my PhD is to trace Tau pathology in different dementia diseases
    grouped in the term of tauopathies. This term includes dementias such as
    Alzheimer´s disease, Progressive Supranuclear Palsy or Fronto-Temporal
    dementia. Our translational group focuses mainly on Positron Emission
    Tomography technique (PET). ​The need is to find PET tracers which could
    be used in clinic for a clear diagnosis and differentiate between these
    dementias. For my PhD, I mainly work on the characterisation and
    understanding of the binding properties of newly designed PET tracers to
    determine their ability to target specifically Tau protein in pathological
    brains compared to healthy brains as well as other characteristic hallmarks
    such as inflammation and amyloid deposition. To do so, I perform binding
    assays studies on postmortem human brain tissue, immunostaining as well
    as a unique technique in our lab which is autoradiography with 100 um
    thick large frozen human brain sections.

Articles

All other publications

Employments

  • Affiliated to Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2024-2025

Degrees and Education

  • Degree Of Doctor Of Philosophy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2024

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