Mikael Sundin

Mikael Sundin

Affiliated to Research | Docent
Visiting address: Enheten för pediatrik, Novum, Blickagången 6A, 14157 Huddinge
Postal address: H9 Klinisk vetenskap, intervention och teknik, H9 CLINTEC Pediatrik, 171 77 Stockholm

About me

  • I’m born in Sweden 1981 and graduated from Medical School 2005 (Karolinska
    Institutet). In 2008, I defended my PhD-thesis “Mesenchymal Stromal Cell
    Transplantation: Possible Viral Complications and Alloimmunity” (Karolinska
    Institutet) and in 2016, I was appointed Associate Professor of Pediatrics
    (Karolinska Institutet).
    My clinical training (Internship and Residency) took place at the Karolinska
    University Hospital and the Astrid Lindgren Children’s
    Hospital. Currently, I work as Senior Consultant in
    Pediatric Hematology/Oncology and Medical Officer for the Immunodeficiency
    (incl. SCID newborn screening) and the HCT programs at the Section for
    Pediatric Hematology/Immunology/Hematopoietic Cell Transplantation
    (HCT) at Astrid Lindgren Children’s Hospital, Karolinska University
    Hospital. Between 2013 – 2020, I served as Head of Section.
    I’m Research Group Leader (PI) at the Division of Pediatrics, CLINTEC,
    Karolinska Institutet – /see below/. My research interest covers immune
    recovery post-HCT and diagnostics (incl. whole genome sequencing) of bone
    marrow failure and immunodeficiency.

Research

  • We are working with clinical research within pediatric hematology, immunology
    and hematopoietic cell transplantation (HCT, aka bone marrow transplantation)
    with the aim to expand the knowledge and to contribute to better diagnostics
    and treatments. We take on our research questions by clinical, epidemiologic
    and experimental methods. Our main research areas are:
    • Allogeneic HCT – immune recovery and complications in the short and
    long term
    • Diagnostics of hematologic conditions and bone marrow failure disorders
    • Rare hematologic cancer in children – e.g., myelodysplastic syndrome
    (MDS), myeloproliferative disorders (MPD) and chronic myeloid leukemia (CML).
    • Diagnostics and clinical care in inborn errors of immunity
    *Coworkers (alphabetic order):*
    */Petra Byström, MD, /*/Senior/*/ /*/Consultant in Pediatric
    Hematology/Oncology and future PhD student/
    The project ”Routine analyses and modern methods in pediatric hematologic
    diagnostics” is about evaluating basic and modern analyses, i.e.,
    everything from full blood counts to whole genome sequencing, in the
    diagnostics of hematologic conditions and after HCT.
    */Sofia Englund, MD, /*/Temporary resident and future PhD-student/
    The project/ /”Bone marrow failure and the use of markers in peripheral
    blood in pediatric patients” is about studying the usage of markers in
    peripheral blood in diagnostics of bone marrow failure with emphasis on
    hCAP-18 in relation to hematopoiesis.
    */Henric Lindqvist, MD, /*/ Resident in Hematology and PhD student/
    The project “Myeloid cell function and importance in pediatric allogeneic
    HCT” is about studying granulocyte recovery, numeric and functional, after
    allogeneic HCT and its possible dysfunction in relation to other immune
    function.
    Henrics page – https://staff.ki.se/people/hlindk
    */Lotta Pramanik-Jonsson, MD, PhD, /*/Resident in Pediatrics and Postdoc/
    The project ”Early and late complications in relation to the conditioning
    regimen in pediatric allogeneic HCT” is about studying complications to HCT
    in relation to etoposide pharmacogenetics and the occurrence of acute
    (subclinical) brain injury.
    Lottas page – https://staff.ki.se/people/lopram
    */Gauti Vilbergsson, MD, /*/Senior Consultant in Pediatric
    Hematology/Oncology and future PhD student/
    The project/ /“Pediatric chronic myeloid leukemia (CML) and
    myeloproliferative disorders (MPD) in Sweden – from clinic to quality of
    life” is about population-based studying clinical aspects, molecular
    genetics and quality of life in these disorders.
    */Magnus Wallner (ex Hansson), MD, /*/ Regional military doctor and PhD
    student/
    The project “Vitamin D and iron status in pediatric allogeneic HCT:
    importance for GvHD, immune recovery and immunity” is about studying the
    impact of micronutrients on the immune system in the context of allogeneic
    HCT.

Articles

All other publications

Employments

  • Affiliated to Research, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 2022-2025

Degrees and Education

  • Docent, Karolinska Institutet, 2016
  • Degree Of Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2008
  • University Medical Degree, Karolinska Institutet, 2005

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