Mattias Svensson

Expertise in preclinical research in the field of immunology and infection,
myeloid immune cells, host pathogen interactions and cell biology.
Conduct translational projects based on preclinical science. 
Particular interest: Infection and immunology, as well as in fibroblasts, human myeloid 
immune cells such as monocytes, dendritic cells and macrophages in acute and
chronic tissue inflammation.
Current position: Research group leader, associate professor.
Is Director of Doctoral Education at the Department of Medicine, Huddinge and
Chairman of the Dissertation Committee at Karolinska Institutet.
1995, MSc, Biology, Lund University, Sweden
2000, PhD, Immunology, Lund University, Sweden
2001-2004, Post doctoral Fellow, London School of Hygiene and Tropical
Medicin, London, UK
2010, Associate Professor, Immunology, Karolinska Institutet, Sweden

Our research group [1] at the Center for Infectious Medicine (CIM [2]),
Department of Medicine, Huddinge conducts research aimed at understanding how
the tissue microenvironment influences the development and function of myeloid immune cellsin homeostasis, infection and chronic inflammatory conditions. In particular the focus is on the ability of tissue-specific cells, especially fibroblasts, to shape the function of myeloid cells. 
We strive to identify proteins and metabolites that are important for
tissue-specific cells, such as fibroblasts, to shape the microenvironment for
the function of myeloid immune cells and the specific properties of bacteria.
The goal is to:
1. Develop customized human organotypic models for homeostasis and disease mechanism 
identification, biomarker detection, and validation of interventions in infection and inflammatory disease.
2. Utilize identified disease mechanisms to develop tailored therapy and
implement personalized medicine in sever infectious diseases caused by bacteria
3. Identify central host-derived mediators which in the tissue environment influences the development and function of human myeloid immune cells. 
[1] https://ki.se/en/medh/mattias-svensson-group-studies-of-tissue-microbiology-and-immunology
[2] https://ki.se/en/medh/center-for-infectious-medicine-cim