Maria Latorre Leal

Publications
CV
Public outreach and news

Articles

Article: BRAIN, BEHAVIOR, AND IMMUNITY. 2024;119:286-300
Dynamic microglia alterations associate with hippocampal network impairments: A turning point in amyloid pathology progression
Pizzirusso G; Preka E; Goikolea J; Aguilar-Ruiz C; Rodriguez-Rodriguez P; Vazquez-Cabrera G; Laterza S; Latorre-Leal M; Eroli F; Blomgren K; Maioli S; Nilsson P; Fragkopoulou A; Fisahn A; Arroyo-Garcia LE
Article: SCIENCE ADVANCES. 2024;10(4):eadj1354
CYP46A1-mediated cholesterol turnover induces sex-specific changes in cognition and counteracts memory loss in ovariectomized mice
Latorre-Leal M; Rodriguez-Rodriguez P; Franchini L; Nikolidakis O; Daniilidou M; Delac L; Varshney MK; Arroyo-Garcia LE; Eroli F; Winblad B; Blennow K; Zetterberg H; Kivipelto M; Pacciarini M; Wang Y; Griffiths WJ; Bjoerkhem I; Matton A; Nalvarte I; Merino-Serrais P; Cedazo-Minguez A; Maioli S
Article: FRONTIERS IN CELLULAR NEUROSCIENCE. 2024;18:1347535
Impaired astrocytic synaptic function by peripheral cholesterol metabolite 27-hydroxycholesterol
Spanos F; Gerenu G; Goikolea J; Latorre-Leal M; Balleza-Tapia H; Gomez K; Alvarez-Jimenez L; Piras A; Gomez-Galan M; Fisahn A; Cedazo-Minguez A; Maioli S; Loera-Valencia R
Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2023;234:106387
Different effects of CYP27A1 and CYP7B1 on cognitive function: Two mouse models in comparison
Goikolea J; Latorre-Leal M; Tsagkogianni C; Pikkupeura S; Gulyas B; Cedazo-Minguez A; Loera-Valencia R; Bjorkhem I; Rodriguez PR; Maioli S
Article: BRAIN COMMUNICATIONS. 2023;5(5):fcad228
Alzheimer's disease biomarker profiling in a memory clinic cohort without common comorbidities
Daniilidou M; Eroli F; Alanko V; Goikolea J; Latorre-Leal M; Rodriguez-Rodriguez P; Griffiths WJ; Wang Y; Pacciarini M; Brinkmalm A; Zetterberg H; Blennow K; Rosenberg A; Bogdanovic N; Winblad B; Kivipelto M; Ibghi D; Cedazo-Minguez A; Maioli S; Matton A
Article: GLIA. 2023;71(6):1414-1428
27-hydroxycholesterol promotes oligodendrocyte maturation: Implications for hypercholesterolemia-associated brain white matter changes
Alanko V; Gaminde-Blasco A; Quintela-Lopez T; Loera-Valencia R; Solomon A; Bjorkhem I; Cedazo-Minguez A; Maioli S; Tabacaru G; Latorre-Leal M; Matute C; Kivipelto M; Alberdi E; Sandebring-Matton A
Article: AGING. 2021;13(11):14729-14744
Long-term exposure to polypharmacy impairs cognitive functions in young adult female mice
Eroli F; Johnell K; Latorre-Leal M; Hilmer S; Wastesson J; Cedazo-Minguez A; Maioli S
Article: AGING. 2020;12(11):10147-10161
Chronic polypharmacy impairs explorative behavior and reduces synaptic functions in young adult mice
Eroli F; Johnell K; Leal ML; Adamo C; Hilmer S; Wastesson JW; Cedazo-Minguez A; Maioli S

All other publications

Thesis / dissertation: 2024
The role of oxysterols in neurodegeneration : implications for cognitive function, maternal effects, and sex-specific differences
Latorre Leal, María
Preprint: BIORXIV. 2022
Alzheimer’s disease biomarker profiling in a memory clinic cohort without common comorbidities
Daniilidou M; Eroli F; Alanko V; Goikolea J; Latorre-Leal M; Rodriguez-Rodriguez P; Griffiths W; Wang Y; Pacciarini M; Brinkmalm A; Zetterberg H; Blennow K; Rosenberg A; Bogdanovic N; Winblad B; Kivipelto M; Ibghi D; Cedazo-Minguez A; Maioli S; Sandebring-Matton A
Preprint: BIORXIV. 2022
Neuron-derived Thioredoxin-80: a novel regulator of type-I interferon response in microglia
Goikolea J; Roussarie J-P; Gerenu G; Loera-Valencia R; Latorre-Leal M; Cedazo-Minguez A; Rodriguez-Rodriguez P; Maioli S
Preprint: RESEARCH SQUARE. 2021
27-Hydroxycholesterol Promotes Oligodendrocyte Maturation – Implications for Hypercholesterolemia Associated Brain White Matter Changes
Alanko V; Quintela-López T; Gaminde-Blasco A; Loera-Valencia R; Solomon A; Björkhem I; Cedazo-Minguez A; Maioli S; Tabacaru G; Latorre-Leal M; Matute C; Kivipelto M; Alberdi E; Matton A
Preprint: BIORXIV. 2021
Sex-dependent effects of CYP46A1 overexpression on cognitive function during aging
Latorre-Leal M; Rodriguez-Rodriguez P; Franchini L; Daniilidou M; Eroli F; Winblad B; Blennow K; Zetterberg H; Kivipelto M; Pacciarini M; Wang Y; Griffiths W; Björkhem I; Sandebring Matton A; Merino-Serrais P; Cedazo-Minguez A; Maioli S

Employments

Postdoctoral Researcher, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2024-2026

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2024

Articles

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Degrees and Education

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