Maria Ankarcrona
Professor | Head of department | Docent
E-mail: maria.ankarcrona@ki.se
Telephone: +46852483577
Visiting address: Bioclinicum J9:20, Akademiska stråket 1, 17164 Huddinge
Postal address: H1 Neurobiologi, vårdvetenskap och samhälle, H1 Neurogeriatrik Ankarcrona, 171 77 Stockholm
About me
- I am Professor of Experimental Neurogeriatics and study cellular mechanisms in Alzheimer's disease. I am head of the Department of Neurobiology, Care Sciences and Society (NVS). I was the director of doctoral studies at NVS between 2012-2017. During the 2015-2018, I was faculty representative on the Board of Doctoral Education (FUS) and during 2019 faculty representative on the Faculty Board. These were very interesting, stimulating and important assignments. To pursue issues that I am passionate about and to be a part of developing KI is both interesting and fun. This is something that I bring with me when I now take over as head of one of KI's largest departments with large assignments in research and education.
Research
- My research focuses on mitochondrial function in Alzheimer's disease with the long-term goal of identifying new drug candidates. Of particular interest is the interaction between the endoplasmic network (ER) and the mitochondria. Until recently, I was the coordinator of an EU project (JPND / VR) where a consortium of five partners aimed to identify common and distinct disease mechanisms in Alzheimer's disease, Parkinson's disease and Huntington's disease with a focus on regulation of mitochondrial function and cellular bioenergtics. As part of project, we have identified a molecule that positively affects mitochondrial function and which we are now developing further.
Teaching
- My educational qualifications are mainly in the postgraduate education where I have been main supervisor for five doctoral students defending their theses and is currently the main supervisor for one doctoral student. I also continuously supervise master's students in their research projects. I am responsible for the neurodegeneration part of the course Frontiers in Translational Medicine within KI's Master's program in Biomedicine and for a doctoral education course on Alzheimer's disease.
Articles
- Article: MOLECULAR PSYCHIATRY. 2023;28(9):3966-3981
- Article: JOURNAL OF NEUROINFLAMMATION. 2023;20(1):43
- Article: JOURNAL OF ALZHEIMER'S DISEASE. 2022;90(2):565-583
- Article: CELLS. 2022;11(3):514
- Article: BMC BIOLOGY. 2021;19(1):229
- Article: NEUROTHERAPEUTICS. 2021;18(2):1017-1038
- Article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2021;9:706687
- Article: AGING CELL. 2019;18(3):e12924
- Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2018;22(11):5439-5449
- Article: ACTA NEUROPATHOLOGICA COMMUNICATIONS. 2018;6(1):102
- Article: JOURNAL OF ALZHEIMER'S DISEASE REPORTS. 2018;2(1):27-39
- Article: CURRENT BIOLOGY. 2018;28(3):369-382.e6
- Article: JOURNAL OF MOLECULAR BIOLOGY. 2018;430(3):348-362
- Journal article: ALZHEIMER'S AND DEMENTIA. 2017;13(7S_Part_18):p886
- Article: METHODS IN MOLECULAR BIOLOGY. 2017;1567:53-68
- Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2016;20(9):1686-1695
- Article: JOURNAL OF ALZHEIMER'S DISEASE. 2014;43(2):369-374
- Journal article: ALZHEIMER'S AND DEMENTIA. 2014;10(4S_Part_3):p215
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(19):7916-7921
- Article: JOURNAL OF ALZHEIMER'S DISEASE. 2012;31(3):527-536
- Article: NEUROCHEMISTRY INTERNATIONAL. 2012;61(1):108-118
- Journal article: ALZHEIMER'S AND DEMENTIA. 2012;8(4S_Part_8):p307-p308
- Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2011;15(10):2150-2163
- Article: THE FASEB JOURNAL. 2011;25(4):1345-1352
- Article: THE FASEB JOURNAL. 2011;25(1):78-88
- Article: NEUROCHEMISTRY INTERNATIONAL. 2010;57(6):668-675
- Article: JOURNAL OF ALZHEIMER'S DISEASE. 2010;21(2):389-402
- Journal article: ALZHEIMER'S AND DEMENTIA. 2010;6(4S_Part_18):s564
- Article: JOURNAL OF BIOENERGETICS AND BIOMEMBRANES. 2009;41(5):447-451
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(35):13145-13150
- Journal article: ALZHEIMER'S AND DEMENTIA. 2008;4(4S_Part_11):t357-t358
- Journal article: ALZHEIMER'S AND DEMENTIA. 2008;4(4S_Part_19):t637
- Journal article: ALZHEIMER'S AND DEMENTIA. 2008;4(4S_Part_19):t610
- Article: PHYSIOLOGY AND BEHAVIOR. 2007;92(1-2):93-97
- Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2007;11(4):810-825
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;350(1):220-226
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(39):29096-29104
- Article: JOURNAL OF NEUROSCIENCE RESEARCH. 2006;84(4):891-902
- Article: JOURNAL OF NEUROSCIENCE RESEARCH. 2006;84(3):596-605
- Article: JOURNAL OF NEUROCHEMISTRY. 2006;97(2):356-364
- Article: JOURNAL OF NEUROSCIENCE RESEARCH. 2005;82(3):432-441
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2004;279(49):51654-51660
- Article: JOURNAL OF ALZHEIMER'S DISEASE. 2004;6(2):123-128
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2004;279(8):6455-6464
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(39):36646-36655
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2002;295(3):766-770
- Article: CURRENT OPINION IN PSYCHIATRY. 2002;15(4):395-401
- Article: JOURNAL OF NEUROSCIENCE RESEARCH. 2001;66(1):122-134
- Article: JOURNAL OF NEUROSCIENCE RESEARCH. 2001;63(5):429-437
- Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2000;4(4):249-261
- Journal article: NEUROBIOLOGY OF AGING. 2000;21:217
- Journal article: NEUROBIOLOGY OF AGING. 2000;21:282
- Journal article: NEUROBIOLOGY OF AGING. 2000;21:163
- Article: NEUROSCIENCE. 2000;95(2):593-601
- Article: BRAIN RESEARCH BULLETIN. 1997;43(4):393-403
- Article: NEUROREPORT. 1996;7(15-17):2659-2664
- Article: FEBS LETTERS. 1996;394(3):321-324
- Journal article: APOPTOSIS : AN INTERNATIONAL JOURNAL ON PROGRAMMED CELL DEATH. 1996;1(1):5-10
- Article: ADVANCES IN NEUROLOGY. 1996;71:137-149
- Article: EXPERIMENTAL CELL RESEARCH. 1995;221(2):404-412
- Article: NEURON. 1995;15(4):961-973
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1995;92(16):7162-7166
- Journal article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1994;269(48):30553-30560
- Journal article: FEBS LETTERS. 1994;355(1):23-26
- Journal article: EXPERIMENTAL CELL RESEARCH. 1994;213(1):172-177
- Journal article: JOURNAL OF IMMUNOLOGY. 1993;150(7):2964-2971
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All other publications
- Review: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2022;10:920228
- Conference publication: JOURNAL OF NEUROLOGY, NEUROSURGERY AND PSYCHIATRY. 2021;92:A52-A53
- Review: JOURNAL OF INTERNAL MEDICINE. 2019;285(6):594-607
- Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2019;285(6):591-593
- Review: CELL DEATH AND DIFFERENTIATION. 2018;25(3):542-572
- Review: NEUROSCIENCE LETTERS. 2018;663:79-85
- Review: JOURNAL OF INTERNAL MEDICINE. 2016;280(2):177-202
- Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2013;23:S150-S151
- Book chapter: STUDIES ON ALZHEIMER'S DISEASE: OXIDATIVE STRESS IN APPLIED BASIC RESEARCH AND CLINICAL PRACTICE. 2013;p. 41-53
- Review: ANTIOXIDANTS AND REDOX SIGNALING. 2012;16(12):1476-1491
- Review: JOURNAL OF ALZHEIMER'S DISEASE. 2010;20:S579-S590
- Review: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2009;13(10):4137-4145
- Book chapter: ABETA PEPTIDE AND ALZHEIMER’S DISEASE. 2007;p. 234-244
- Conference publication: THE FEBS JOURNAL. 2007;274:167
- Review: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2005;20(2):101-105
- Meeting abstract: NEUROBIOLOGY OF AGING. 2004;25:s549
- Meeting abstract: NEUROBIOLOGY OF AGING. 2004;25:S525
- Conference publication: FUNDAMENTAL AND CLINICAL PHARMACOLOGY. 2004;18:15
- Conference publication: NEUROBIOLOGY OF AGING. 2002;23(1):S220-S221
- Conference publication: NEUROBIOLOGY OF AGING. 2002;23(1):S215
- Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2002;12:S56
- Review: PROGRESS IN BRAIN RESEARCH. 1998;116:265-272
- Book chapter: APOPTOSIS TECHNIQUES AND PROTOCOLS: NEUROMETHODS. 1997;p. 237-253
- Review: ADVANCES IN NEUROLOGY. 1997;72:95-101
- Thesis / dissertation: 1996
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Grants
- Swedish Research Council1 January 2023 - 31 December 2025
- Swedish Research Council1 January 2019 - 31 December 2022
- JPND utlysning 2013. Cross-Disease analysis of pathways. CeBioN, Cellular Bioenergetics in Neurodegenerative Diseases: A system-based pathway and target analysisSwedish Research Council1 December 2014 - 31 December 2016
- Deutsche Forschungsgemeinschaft1 January 2013 - 31 December 2015
- Swedish Research Council1 January 2012 - 31 December 2014
Employments
- Professor, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2018-
Degrees and Education
- Docent, Karolinska Institutet, 2004
- Master's degree, Biology and chemistry, Stockholm University, 1991
Leadership and responsibility assignments
- Head of department, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2021-