Mai-Lis Hellenius

About me
Publications
CV
Public outreach and news

About me

Since I started out as a researcher in 1987, my research and that of my colleagues has been focused on cardiovascular prevention and the role of lifestyle in cardiovascular health, with a special interest in physical activity and nutrition. For scientific production, please view the publication list.

My research group collaborates closely with several other research groups in epidemiology, health economics, metabolism, molecular biology, and molecular genetics at Karolinska Institutet, Uppsala University, GIH – the Swedish School of Sport and Health Sciences, and Umeå University. We also have collaborations with research groups internationally.

I have delivered about 150 scientific presentations as an invited speaker at international meetings and about 450 presentations at national scientific meetings. In addition to these overview lectures, I have also presented my own work in the form of some 70 abstracts at scientific meetings.

Throughout my career, I have also engaged with the wider society and shared my knowledge of the importance of lifestyle for health. I have contributed to countless newspaper articles, radio and TV features, cookbooks, and self-help programs.

Articles

Article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (EJPC). 2021;28(12):1376-1385
Physical activity attenuates cardiovascular risk and mortality in men and women with and without the metabolic syndrome - a 20-year follow-up of a population-based cohort of 60-year-olds
Ekblom-Bak E; Halldin M; Vikstrom M; Stenling A; Gigante B; de Faire U; Leander K; Hellenius M-L
Article: AMERICAN JOURNAL OF LIFESTYLE MEDICINE. 2021;15(1):28-38
Effects of Structured Lifestyle Education Program for Individuals With Increased Cardiovascular Risk Associated With Educational Level and Socioeconomic Area
Lidin M; Hellenius M-L; Karlsson MR; Ekblom-Bak E
Article: BMC PUBLIC HEALTH. 2020;20(1):1911
"We were all together"- families' experiences of the health-promoting programme - A Healthy Generation
Andermo S; Lidin M; Hellenius M-L; Nordenfelt A; Nyberg G
Article: BRITISH JOURNAL OF SPORTS MEDICINE. 2020;54(21):1294-1299
A Swedish primary healthcare prevention programme focusing on promotion of physical activity and a healthy lifestyle reduced cardiovascular events and mortality: 22-year follow-up of 5761 study participants and a reference group
Journath G; Hammar N; Vikstrom M; Linnersjo A; Walldius G; Krakau I; Lindgren P; de Faire U; Hellenius M-L
Article: EUROPEAN JOURNAL OF NUTRITION. 2020;59(5):2089-2097
Association between carbohydrate intake and fatty acids in the de novo lipogenic pathway in serum phospholipids and adipose tissue in a population of Swedish men
Alsharari ZD; Leander K; Sjogren P; Carlsson A; Cederholm T; de Faire U; Hellenius M-L; Marklund M; Riserus U
Article: BMC PUBLIC HEALTH. 2020;20(1):809
Effectiveness of a family intervention on health-related quality of life-a healthy generation, a controlled pilot trial
Andermo S; Hellenius M-L; Lidin M; Hedby U; Nordenfelt A; Nyberg G
Article: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2020;17(11):E3794-3794
Effectiveness of a Family Intervention to Increase Physical Activity in Disadvantaged Areas-A Healthy Generation, a Controlled Pilot Study
Nyberg G; Andermo S; Nordenfelt A; Lidin M; Hellenius M-L
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2020;111(4):749-756
A randomized clinical trial of the effects of leafy green vegetables and inorganic nitrate on blood pressure
Sundqvist ML; Larsen FJ; Carlstrom M; Bottai M; Pernow J; Hellenius M-L; Weitzberg E; Lundberg JO
Article: BMC SPORTS SCIENCE, MEDICINE AND REHABILITATION. 2020;12(1):11
Long-term effects of group exercise intervention on maximal step-up height in middle-aged female primary care patients with obesity and other cardio-metabolic risk factors
Nyberg LA; Sundberg CJ; Wandell P; Kowalski J; Hellenius M-L
Article: EUROPEAN JOURNAL OF CARDIOVASCULAR NURSING. 2019;18(7):554-561
Experiences from individuals with increased cardiovascular risk participating in a one-year lifestyle program
Lidin M; Hellenius M-L; Ekblom-Bak E; Karlsson MR
Article: CIRCULATION. 2019;139(21):2422-2436
Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality: An Individual-Level Pooled Analysis of 30 Cohort Studies
Marklund M; Wu JHY; Imamura F; Del Gobbo LC; Fretts A; de Goede J; Shi P; Tintle N; Wennberg M; Aslibekyan S; Chen T-A; Otto MCDO; Hirakawa Y; Eriksen HH; Kroeger J; Laguzzi F; Lankinen M; Murphy RA; Prem K; Samieri C; Virtanen J; Wood AC; Wong K; Yang W-S; Zhou X; Baylin A; Boer JMA; Brouwer IA; Campos H; Chaves PHM; Chien K-L; de Faire U; Djousse L; Eiriksdottir G; El-Abbadi N; Forouhi NG; Gaziano JM; Geleijnse JM; Gigante B; Giles G; Guallar E; Gudnason V; Harris T; Harris WS; Helmer C; Hellenius M-L; Hodge A; Hu FB; Jacques PF; Jansson J-H; Kalsbeek A; Khaw K-T; Koh W-P; Laakso M; Leander K; Lin H-J; Lind L; Luben R; Luo J; McKnight B; Mursu J; Ninomiya T; Overvad K; Psaty BM; Rimm E; Schulze MB; Siscovick D; Nielsen MS; Smith AV; Steffen BT; Steffen L; Sun Q; Sundstrom J; Tsai MY; Tunstall-Pedoe H; Uusitupa MIJ; van Dam RM; Veenstra J; Verschuren WMM; Wareham N; Willett W; Woodward M; Yuan J-M; Micha R; Lemaitre RN; Mozaffarian D; Riserus U
Article: CLINICAL NUTRITION. 2018;37(6):2001-2010
Circulating fatty acids in relation to alcohol consumption: Cross-sectional results from a cohort of 60-year-old men and women
Laguzzi F; Riserus U; Marklund M; Vikstrom M; Sjogren R; Gigante B; Alsharari ZD; Hellenius M-L; Cederholm T; Frumento P; de Faire U; Leander K
Article: AGING. 2018;10(10):3005-3016
Longitudinal changes in leukocyte telomere length and mortality in elderly Swedish men
Yuan X; Kronstrom M; Hellenius M-L; Cederholm T; Xu D; Sjogren P
Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2018;46(6):613-622
Long-term effects of a Swedish lifestyle intervention programme on lifestyle habits and quality of life in people with increased cardiovascular risk
Lidin M; Ekblom-Bak E; Karlsson MR; Hellenius M-L
Article: BMC CARDIOVASCULAR DISORDERS. 2018;18(1):59
Long-term effects on cardiovascular risk of a structured multidisciplinary lifestyle program in clinical practice
Lidin M; Hellenius M-L; Rydell-Karlsson M; Ekblom-Bak E
Article: LAKARTIDNINGEN. 2018;115:EY33
Prevention av diabetes typ 2 med fysisk aktivitet och hälsosam mat - En framgångsrik dialog om livsstil bygger på individanpassade och evidensbaserade råd.
Hellénius M-L
Article: JOURNAL OF GERIATRIC PHYSICAL THERAPY. 2017;40(2):102-111
Short- and Long-Term Effects of Balance Training on Physical Activity in Older Adults With Osteoporosis: A Randomized Controlled Trial
Dohrn I-M; Hagstromer M; Hellenius M-L; Stahle A
Article: PLOS ONE. 2017;12(1):e0170684
Serum Fatty Acids, Desaturase Activities and Abdominal Obesity - A Population-Based Study of 60-Year Old Men and Women
Alsharari ZD; Riserus U; Leander K; Sjogren P; Carlsson AC; Vikstrom M; Laguzzi F; Gigante B; Cederholm T; De Faire U; Hellenius M-L; Marklund M
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2016;5(12):e004415
Human IgM Antibodies to Malondialdehyde Conjugated With Albumin Are Negatively Associated With Cardiovascular Disease Among 60-Year-Olds
Thiagarajan D; Frostegard AG; Singh S; Rahman M; Liu A; Vikstrom M; Leander K; Gigante B; Hellenius M-L; Zhang B; Zubarev RA; de Faire U; Lundstrom SL; Frostegard J
Article: JOURNAL OF HUMAN NUTRITION AND DIETETICS. 2016;29(3):325-337
Cross-sectional relationships between dietary fat intake and serum cholesterol fatty acids in a Swedish cohort of 60-year-old men and women
Laguzzi F; Alsharari Z; Riserus U; Vikstrom M; Sjogren P; Gigante B; Hellenius M-L; Cederholm T; Bottai M; de Faire U; Leander K
Article: CIRCULATION. 2016;133(13):1230-1239
Circulating Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Predicts Future Risk of Cardiovascular Events Independently of Established Risk Factors
Leander K; Malarstig A; van't Hooft FM; Hyde C; Hellenius M-L; Troutt JS; Konrad RJ; Ohrvik J; Hamsten A; de Faire U
Article: JOURNAL OF AGING AND PHYSICAL ACTIVITY. 2016;24(1):22-31
Gait Speed, Quality of Life, and Sedentary Time are Associated with Steps per Day in Community-Dwelling Older Adults. with Osteoporosis
Dohrn I-M; Hagstromer M; Hellenius M-L; Stahle A
Article: CIRCULATION. 2015;132(7):586-594
Polyunsaturated Fat Intake Estimated by Circulating Biomarkers and Risk of Cardiovascular Disease and All-Cause Mortality in a Population-Based Cohort of 60-Year-Old Men and Women
Marklund M; Leander K; Vikstrom M; Laguzzi F; Gigante B; Sjogren P; Cederholm T; de Faire U; Hellenius M-L; Riserus U
Article: BMC PUBLIC HEALTH. 2015;15:687
Effects of the Swedish physical activity on prescription model on health-related quality of life in overweight older adults: a randomised controlled trial
Olsson SJG; Borjesson M; Ekblom-Bak E; Hemmingsson E; Hellenius M-L; Kallings LV
Article: PLOS ONE. 2015;10(5):e0127111
Obesity, Metabolic Syndrome and Risk of Atrial Fibrillation: A Swedish, Prospective Cohort Study
Nystrom PK; Carlsson AC; Leander K; de Faire U; Hellenius M-L; Gigante B
Article: PLOS ONE. 2015;10(11):e0140201
Time Trends in Incidence and Mortality of Acute Myocardial Infarction, and All-Cause Mortality following a Cardiovascular Prevention Program in Sweden
Journath G; Hammar N; Elofsson S; Linnersjo A; Vikstrom M; Walldius G; Krakau I; Lindgren P; de Faire U; Hellenius M-L
Article: PREVENTIVE MEDICINE. 2014;69:151-156
Differences in anthropometric measures in immigrants and Swedish-born individuals: Results from two community-based cohort studies
Carlsson AC; Wandell P; Riserus U; Arnlov J; Borne Y; Engstrom G; Leander K; Gigante B; Hellenius M-L; de Faire U
Article: BRITISH JOURNAL OF SPORTS MEDICINE. 2014;48(19):1407-1409
Stand up for health-avoiding sedentary behaviour might lengthen your telomeres: secondary outcomes from a physical activity RCT in older people
Sjogren P; Fisher R; Kallings L; Svenson U; Roos G; Hellenius M-L
Article: NUTRITION, METABOLISM AND CARDIOVASCULAR DISEASES. 2014;24(8):891-899
Prediction of cardiovascular disease by abdominal obesity measures is dependent on body weight and sex - Results from two community based cohort studies
Carlsson AC; Riserus U; Arnlov J; Borne Y; Leander K; Gigante B; Hellenius M-L; Bottai M; de Faire U
Article: SCANDINAVIAN JOURNAL OF MEDICINE AND SCIENCE IN SPORTS. 2014;24(2):319-326
A new submaximal cycle ergometer test for prediction of VO_2max
Ekblom-Bak E; Bjorkman F; Hellenius M-L; Ekblom B
Article: BRITISH JOURNAL OF SPORTS MEDICINE. 2014;48(3):233-238
The importance of non-exercise physical activity for cardiovascular health and longevity
Ekblom-Bak E; Ekblom B; Vikstrom M; de Faire U; Hellenius M-L
Article: BMC PUBLIC HEALTH. 2014;14:17
Financial stress in late adulthood and diverse risks of incident cardiovascular disease and all-cause mortality in women and men
Carlsson AC; Starrin B; Gigante B; Leander K; Hellenius M-L; de Faire U
Article: PLOS ONE. 2014;9(12):e108872
The Metabolic Syndrome and ECG Detected Left Ventricular Hypertrophy - Influences from IGF-1 and IGF-Binding Protein-1
Halldin M; Brismar K; Fahlstadius P; Vikstrom M; de Faire U; Hellenius M-L
Article: INTERNATIONAL JOURNAL OF OBESITY. 2013;37(12):1579-1585
Novel and established anthropometric measures and the prediction of incident cardiovascular disease: a cohort study
Carlsson AC; Riserus U; Engstrom G; Arnlov J; Melander O; Leander K; Gigante B; Hellenius M-L; de Faire U
Article: BRITISH JOURNAL OF SPORTS MEDICINE. 2013;47(15):992-997
Maximal step-up height as a simple and relevant health indicator: a study of leg muscle strength and the associations to age, anthropometric variables, aerobic fitness and physical function
Nyberg LA; Hellenius M-L; Wandell P; Kowalski J; Sundberg CJ
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2013;168(2):946-952
Seven modifiable lifestyle factors predict reduced risk for ischemic cardiovascular disease and all-cause mortality regardless of body mass index: A cohort study
Carlsson AC; Wandell PE; Gigante B; Leander K; Hellenius M-L; de Faire U
Article: BMC CARDIOVASCULAR DISORDERS. 2013;13:1
Low levels of IgM antibodies to oxidized cardiolipin increase and high levels decrease risk of cardiovascular disease among 60-year olds: a prospective study
Su J; Hua X; Vikstrom M; Leander K; Gigante B; Hellenius M-L; de Faire U; Frostegard J
Article: PLOS ONE. 2013;8(4):e61763
The Risk of Type 2 Diabetes in Men Is Synergistically Affected by Parental History of Diabetes and Overweight
Wikner C; Gigante B; Hellenius M-L; de Faire U; Leander K
Article: LAKARTIDNINGEN. 2012;109(36):1532-1533
[Healthy lifestyle protects the cardiovascular system. We know it!].
Hellénius M-L
Article: THROMBOSIS RESEARCH. 2012;130(2):221-225
Relationships of plasma factor VIIa-antithrombin complexes to manifest and future cardiovascular disease
Silveira A; Scanavini D; Boquist S; Ericsson C-G; Hellenius M-L; Leander K; de Faire U; Ohrvik J; Woodhams B; Morrissey JH; Hamsten A
Article: LIPIDS IN HEALTH AND DISEASE. 2012;11:80
Functional changes in adipose tissue in a randomised controlled trial of physical activity
Sjogren P; Sierra-Johnson J; Kallings LV; Cederholm T; Kolak M; Halldin M; Brismar K; de Faire U; Hellenius M-L; Fisher RM
Article: BLOOD PRESSURE. 2012;21(3):153-160
The metabolic syndrome and left ventricular hypertrophy - the influence of gender and physical activity
Halldin M; Fahlstadius P; de Faire U; Vikstrom M; Hellenius M-L
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2012;32(6):1526-1534
Common and Low-Frequency Genetic Variants in the PCSK9 Locus Influence Circulating PCSK9 Levels
Chernogubova E; Strawbridge R; Mahdessian H; Malarstig A; Krapivner S; Gigante B; Hellenius M-L; de Faire U; Franco-Cereceda A; Syvaenen A-C; Troutt JS; Konrad RJ; Eriksson P; Hamsten A; van 't Hooft FM
Article: JOURNAL OF INTERNAL MEDICINE. 2011;270(3):229-236
Plasma CD93 concentration is a potential novel biomarker for coronary artery disease
Malarstig A; Silveira A; Wagsater D; Ohrvik J; Backlund A; Samnegard A; Khademi M; Hellenius M-L; Leander K; Olsson T; Uhlen M; de Faire U; Eriksson P; Hamsten A
Article: BMC MUSCULOSKELETAL DISORDERS. 2011;12:191
Repeatability and validity of a standardised maximal step-up test for leg function-a diagnostic accuracy study
Nyberg LA; Hellenius M-L; Kowalski J; Wandell P; Andersson P; Sundberg CJ
Article: NATURE GENETICS. 2011;43(4):339-U89
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease
Peden JF; Hopewell JC; Saleheen D; Chambers JC; Hager J; Soranzo N; Collins R; Danesh J; Elliott P; Farrall M; Stirrups K; Zhang W; Hamsten A; Parish S; Lathrop M; Watkins H; Clarke R; Deloukas P; Kooner JS; Goel A; Ongen H; Strawbridge RJ; Heath S; Malarstig A; Helgadottir A; Ohrvik J; Murtaza M; Potter S; Hunt SE; Delepine M; Jalilzadeh S; Axelsson T; Syvanen A-C; Gwilliam R; Bumpstead S; Gray E; Edkins S; Folkersen L; Kyriakou T; Franco-Cereceda A; Gabrielsen A; Seedorf U; Eriksson P; Offer A; Bowman L; Sleight P; Armitage J; Peto R; Abecasis G; Ahmed N; Caulfield M; Donnelly P; Froguel P; Kooner AS; McCarthy MI; Samani NJ; Scott J; Sehmi J; Silveira A; Hellenius M-L; van't Hooft FM; Olsson G; Rust S; Assmann G; Barlera S; Tognoni G; Franzosi MG; Linksted P; Green FR; Rasheed A; Zaidi M; Shah N; Samuel M; Mallick NH; Azhar M; Zaman KS; Samad A; Ishaq M; Gardezi AR; Memon F-U; Frossard PM; Spector T; Peltonen L; Nieminen MS; Sinisalo J; Salomaa V; Ripatti S; Bennett D; Leander K; Gigante B; de Faire U; Pietri S; Gori F; Marchioli R; Sivapalaratnam S; Kastelein JJP; Trip MD; Theodoraki EV; Dedoussis GV; Engert JC; Yusuf S; Anand SS
Article: NUTRITION, METABOLISM AND CARDIOVASCULAR DISEASES. 2011;21(3):173-181
Prevalence of blood lipid disturbances in Swedish and foreign-born 60-year-old men and women in Stockholm, Sweden
Wandell PE; Carlsson AC; de Faire U; Hellenius M-L
Article: PLOS ONE. 2011;6(6):e21485
Blood Cell Telomere Length Is a Dynamic Feature
Svenson U; Nordfjall K; Baird D; Roger L; Osterman P; Hellenius M-L; Roos G
Article: EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2010;64(12):1450-1456
Simple advice on lifestyle habits and long-term changes in biomarkers of inflammation and vascular adhesion in healthy middle-aged men
Sjogren P; Cederholm T; Heimburger M; Stenvinkel P; Vedin I; Palmblad J; Hellenius M-L
Article: BLOOD PRESSURE. 2010;19(4):240-248
Physicians' gender is associated with risk factor control in patients on antihypertensive and lipid lowering treatment
Journath G; Hellenius M-L; Carlsson AC; Wandell PE; Nilsson PM
Article: JOURNAL OF CARDIOVASCULAR RISK. 2010;17(2):175-180
Independent associations of physical activity and cardiovascular fitness with cardiovascular risk in adults
Ekblom-Bak E; Hellenius M-L; Ekblom O; Engstrom L-M; Ekblom B
Article: EUROPEAN HEART JOURNAL. 2010;30(6):710-717
Concentration of apolipoprotein B is comparable with the apolipoprotein B/apolipoprotein A-I ratio and better than routine clinical lipid measurements in predicting coronary heart disease mortality: findings from a multi-ethnic US population
Sierra-Johnson J; Fisher RM; Romero-Corral A; Somers VK; Lopez-Jimenez F; Ohrvik J; Walldius G; Hellenius M-L; Hamsten A
Article: JOURNAL OF AUTOIMMUNITY. 2010;34(2):73-79
Low levels of IgM antibodies to phosphorylcholine predict cardiovascular disease in 60-year old men: Effects on uptake of oxidized LDL in macrophages as a potential mechanism
de Faire U; Su J; Hua X; Frostegard A; Halldin M; Hellenius M-L; Wikstrom M; Dahlbom I; Gronlund H; Frostegard J
Article: BRITISH JOURNAL OF SPORTS MEDICINE. 2010;44(2):121-126
Daily energy expenditure and cardiovascular risk in Masai, rural and urban Bantu Tanzanians
Mbalilaki JA; Masesa Z; Stromme SB; Hostmark AT; Sundquist J; Wandell P; Rosengren A; Hellenius M-L
Article: JOURNAL OF OBESITY. 2010;2010:757939-7
Sagittal abdominal diameter as a screening tool in clinical research: cutoffs for cardiometabolic risk.
Risérus U; de Faire U; Berglund L; Hellénius M-L
Article: JOURNAL OF INTERNAL MEDICINE. 2009;266(6):547-557
Fitness and abdominal obesity are independently associated with cardiovascular risk
Ekblom-Bak E; Hellenius M-L; Ekblom O; Engstrom L-M; Ekblom B
Article: SCANDINAVIAN JOURNAL OF MEDICINE AND SCIENCE IN SPORTS. 2009;19(5):740-747
Importance of enjoyment when promoting physical exercise
Hagberg LA; Lindahl B; Nyberg L; Hellenius M-L
Article: HYPERTENSION RESEARCH. 2009;32(9):780-785
Factors associated with uncontrolled hypertension and cardiovascular risk in hypertensive 60-year-old men and women-a population-based study
Carlsson AC; Wandell PE; Journath G; de Faire U; Hellenius M-L
Article: LIPIDS IN HEALTH AND DISEASE. 2009;8:37
Associations between estimated fatty acid desaturase activities in serum lipids and adipose tissue in humans: links to obesity and insulin resistance
Warensjo E; Rosell M; Hellenius M-L; Vessby B; De Faire U; Riserus U
Article: JOURNAL OF PHYSICAL ACTIVITY AND HEALTH. 2009;6(4):483-492
Self-Reported Adherence: A Method for Evaluating Prescribed Physical Activity in Primary Health Care Patients
Kallings LV; Leijon ME; Kowalski J; Hellenius M-L; Stahle A
Article: METABOLIC SYNDROME AND RELATED DISORDERS. 2009;7(3):231-241
Is a Unified Definition of Metabolic Syndrome Needed? Comparison of Three Definitions of Metabolic Syndrome in 60-Year-Old Men and Women
Carlsson AC; Wasndell PE; Halldin M; de Faire U; Hellenius M-L
Article: CLINICAL SCIENCE. 2009;116(5-6):507-512
IGF-I/IGFBP-3 ratio: a mechanistic insight into the metabolic syndrome
Sierra-Johnson J; Romero-Corral A; Somers VK; Lopez-Jimenez F; Malarstig A; Brismar K; Hamsten A; Fisher RM; Hellenius M-L
Article: BLOOD PRESSURE. 2009;18(3):105-110
Cardiovascular and total mortality in men and women with different blood pressure levels - A 26-year follow-up
Carlsson AC; Theobald H; Hellenius M-L; Wandell PE
Article: JOURNAL OF HYPERTENSION. 2008;26(12):2295-2302
Prevalence of hypertension in immigrants and Swedish-born individuals, a cross-sectional study of 60-year-old men and women in Sweden
Carlsson AC; Wandell PE; de Faire U; Hellenius M-L
Article: JOURNAL OF HYPERTENSION. 2008;26(10):2050-2056
Association of physician's sex with risk factor control in treated hypertensive patients from Swedish primary healthcare
Journath G; Hellenius M-L; Manhem K; Kjellgren KI; Nilsson PM
Article: DIABETES AND METABOLISM. 2008;34(4):328-333
Estimation of diabetes prevalence among immigrants from the Middle East in Sweden by using three different data sources
Wandell PE; Johansson SE; Gafvels C; Hellenius ML; de Faire U; Sundquist J
Article: AMERICAN JOURNAL OF HYPERTENSION. 2008;21(7):771-777
Risk factors associated with newly diagnosed high blood pressure in men and women
Carlsson AC; Wandell PE; de Faire U; Hellenius M-L
Article: OBESITY. 2008;16(6):1302-1307
Eating meals irregularly:: A novel environmental risk factor for the metabolic syndrome
Sierra-Johnson J; Unden A-L; Linestrand M; Rosell M; Sjogren P; Kolak M; De Faire U; Fisher RM; Hellenius M-L
Article: OBESITY. 2008;16(6):1308-1313
Impact of social support intensity on walking in the severely obese:: A randomized clinical trial
Hemmingsson E; Hellenius M-L; Ekelund U; Bergstrom J; Rossner S
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2008;93(5):1995-2001
Insulin-induced gene 2 involvement in human adipocyte metabolism and body weight regulation
Krapivner S; Popov S; Chernogubova E; Hellenius M-L; Fisher RM; Hamsten A; van't Hooft FM
Article: LAKARTIDNINGEN. 2008;105(15):1116-1117
[Contradictory diet advice confusing].
Hellénius M-L
Article: SCANDINAVIAN JOURNAL OF MEDICINE AND SCIENCE IN SPORTS. 2008;18(2):154-161
Physical activity on prescription in primary health care:: a follow-up of physical activity level and quality of life
Kallings LV; Leijon M; Hellenius M-L; Stahle A
Article: METABOLISM: CLINICAL AND EXPERIMENTAL. 2008;57(3):362-366
Autoantibodies against modified apolipoprotein B-100 in relation to low-density lipoprotein size and the metabolic syndrome in otherwise healthy men
Sjogren P; Fredrikson GN; Rosell M; de Faire U; Hamsten A; Nilsson J; Hellenius M-L; Fisher RM
Article: DIABETOLOGIA. 2008;51(2):328-335
Fatty acid desaturases in human adipose tissue:: relationships between gene expression, desaturation indexes and insulin resistance
Sjogren P; Sierra-Johnson J; Gertow K; Rosell M; Vessby B; de Faire U; Hamsten A; Hellenius M-L; Fisher RM
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2008;23(6):431-434
Association between metabolic effects and tobacco use in 60-year-old Swedish men
Wandell PE; Bolinder G; de Faire U; Hellenius M-L
Article: ATHEROSCLEROSIS. 2007;195(2):e168-e175
Markers of endothelial activity are related to components of the metabolic syndrome, but not to circulating concentrations of the advanced glycation end-product Nε-carboxymethyl-lysine in healthy Swedish men
Sjogren P; Basta G; de Caterina R; Rosell M; Basu S; Silveira A; de Faire U; Vessby B; Hamsten A; Hellenius M-L; Fisher RM
Article: JOURNAL OF INTERNAL MEDICINE. 2007;262(5):537-544
Life style habits such as alcohol consumption and physical activity in relation to serum apoB/apoA-I ratio amongst 64-year-old women with varying degrees of glucose tolerance
Simonsson M; Schmidt C; Sigurdadottir V; Helenius M-L; Fagerberg B
Article: EUROPEAN HEART JOURNAL. 2007;28(21):2637-2643
ApoB/apoA-1 ratio:: an independent predictor of insulin resistance in US non-diabetic subjects
Sierra-Johnson J; Romero-Corral A; Somers VK; Lopez-Jimenez F; Walldius G; Hamsten A; Hellenius M-L; Fisher RM
Article: NUTRITION, METABOLISM AND CARDIOVASCULAR DISEASES. 2007;17(8):598-608
High intake of alcohol is associated with newly diagnosed diabetes in 60 years old men and women
Wandell PE; de Faire U; Hellenius M-L
Article: NUTRITION, METABOLISM AND CARDIOVASCULAR DISEASES. 2007;17(5):349-357
The metabolic syndrome:: Prevalence and association to leisure-time and work-related physical activity in 60-year-old men and women
Halldin M; Rosell M; de Faire U; Hellenius M-L
Article: NUTRITION, METABOLISM AND CARDIOVASCULAR DISEASES. 2007;17(5):344-348
Physical activity and blood lipids in rural and urban Tanzanians
Mbalilaki JA; Hellenius M-L; Masesa Z; Hostmark AT; Sundquist J; Stromme SB
Article: LAKARTIDNINGEN. 2007;104(14-15):1164
[Regular physical exercise and training for the long-distance ski race "Vasaloppet" matters].
Hellénius M-L
Article: DIABETES AND METABOLISM. 2007;33(1):30-36
Increased prevalence of diabetes among immigrants from non-European countries in 60-year-old men and women in Sweden
Wandell P-E; Wajngot A; de Faire U; Hellenius M-L
Article: INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE. 2007;23(2):177-183
Lifestyle intervention to prevent diabetes in men and women with impaired glucose tolerance is cost-effective
Lindgren P; Lindstrom J; Tuomilehto J; Uusitupa M; Peltonen M; Jonsson B; de Faire U; Hellenius M-L
Article: EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2006;60(12):1406-1413
Fatty acid handling protein expression in adipose tissue, fatty acid composition of adipose tissue and serum, and markers of insulin resistance
Gertow K; Rosell M; Sjogren P; Eriksson P; Vessby B; de Faire U; Hamsten A; Hellenius M-L; Fisher RM
Article: PLOS GENETICS. 2006;2(5):755-761
Genome-wide mapping of susceptibility to coronary artery disease identifies a novel replicated locus on chromosome 17
Farrall M; Green FR; Peden JF; Olsson PG; Clarke R; Hellenius M-L; Rust S; Lagercrantz J; Franzosi MG; Schulte H; Carey A; Olsson G; Assmann G; Tognoni G; Collins R; Hamsten A; Watkins H
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2005;25(12):2580-2586
Measures of oxidized low-density lipoprotein and oxidative stress are not related and not elevated in otherwise healthy men with the metabolic syndrome
Sjogren P; Basu S; Rosell M; Silveira A; de Faire U; Vessby B; Hamsten A; Hellenius ML; Fisher RM
Article: SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE. 2005;23(2):75-81
Reduction of high cholesterol levels associated with younger age and longer education in a primary health care programme for cardiovascular prevention
Hellénius ML; Nilsson P; Elofsson S; Johansson J; Krakau I
Article: BRITISH JOURNAL OF NUTRITION. 2005;93(1):115-121
The relation between alcohol intake and physical activity and the fatty acids 14:0, 15:0 and 17:0 in serum phospholipids and adipose tissue used as markers for dairy fat intake
Rosell M; Johansson G; Berglund L; Vessby B; de Faire U; Hellénius ML
Article: INTERNATIONAL JOURNAL OF OBESITY. 2004;28(11):1427-1434
Associations between the intake of dairy fat and calcium and abdominal obesity
Rosell M; Johansson G; Berglund L; Vessby B; de Faire U; Hellénius ML
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2003;78(1):84-90
Associations between diet and the metabolic syndrome vary with the validity of dietary intake data.
Rosell MS; Hellénius M-LB; de Faire UH; Johansson GK
Article: PREVENTIVE MEDICINE. 2003;36(4):403-409
Cost-effectiveness of primary prevention of coronary heart disease through risk factor intervention in 60-year-old men from the county of Stockholm -: a stochastic model of exercise and dietary advice
Lindgren P; Fahlstadius P; Hellenius ML; Jönsson B; de Faire U
Article: EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2003;57(2):227-234
Low prevalence of the metabolic syndrome in wine drinkers -: is it the alcohol beverage or the lifestyle?
Rosell M; de Faire U; Hellénius ML
Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2003;33(1):51-57
In vitro and in vivo lipolysis of plasma triglycerides increases the resistance to oxidative modification of low-density lipoproteins
Skoglund-Andersson C; Karpe F; Hellénius ML; Regnström J; Hamsten A; Tornvall P
Article: LAKARTIDNINGEN. 2000;97(14):1678-1685
[Multidisciplinary cooperation behind a quality registry for carotid surgery. Good coverage during the first two years].
Wahlgren NG; Bergqvist D; Hellenius ML; Holtås S; Jogestrand T; Lindqvist M; Norrving B; Troëng T; von Arbin M
Article: JOURNAL OF INTERNAL MEDICINE. 1999;246(2):219-226
Serum urate determines antioxidant capacity in middle-aged men -: a controlled, randomized diet and exercise intervention study
Rosell M; Regnström J; Kallner A; Hellénius ML
Article: SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE. 1999;17(2):111-115
Four years experience of a cardiovascular opportunistic screening and prevention programme in the primary health care in Sollentuna, Sweden
Hellénius ML; Johansson J; de Faire U; Elofsson S; Krakau I
Article: AMERICAN JOURNAL OF PREVENTIVE MEDICINE. 1999;16(4):322-324
Self-report as a selection instrument in screening for cardiovascular disease risk
Johansson J; Hellénius ML; Elofsson S; Krakau I
Article: METABOLISM: CLINICAL AND EXPERIMENTAL. 1999;48(3):301-307
Differences in postprandial concentrations of very-low-density lipoprotein and chylomicron remnants between normotriglyceridemic and hypertriglyceridemic men with and without coronary heart disease
Karpe F; Hellénius ML; Hamsten A
Article: ATHEROSCLEROSIS. 1998;141(2):307-314
Magnitude of alimentary lipemia is related to intima-media thickness of the common carotid artery in middle-aged men
Karpe F; de Faire U; Mercuri M; Bond MG; Hellenius ML; Hamsten A
Article: ATHEROSCLEROSIS. 1998;137(2):391-400
Effects of a cardioselective β-blocker on postprandial triglyceride-rich lipoproteins, low density lipoprotein particle size and glucose-insulin homeostasis in middle-aged men with modestly increased cardiovascular risk
Boquist S; Ruotolo G; Hellénius ML; Danell-Toverud K; Karpe F; Hamsten A
Article: JOURNAL OF INTERNAL MEDICINE. 1998;243(2):109-113
Helicobacter pylori seropositivity is not associated with inflammatory parameters, lipid concentrations and degree of coronary artery disease
Regnström J; Jovinge S; Båvenholm P; Ericsson CG; De Faire U; Hamsten A; Hellenius ML; Nilsson J; Tornvall P
Article: NUTRITION, METABOLISM AND CARDIOVASCULAR DISEASES. 1997;7(4):293-300
Favourable long-term effects from advice on diet and exercise given to healthy men with raised cardiovascular risk factors
Hellenius ML; Krakau I; deFaire U
Article: PATIENT EDUCATION AND COUNSELING. 1996;29(3):247-256
Determinants of compliance in men enrolled in a diet and exercise intervention trial: A randomized, controlled study
Naslund GK; Fredrikson M; Hellenius ML; deFaire U
Article: JOURNAL OF CARDIOVASCULAR RISK. 1996;3(4):379-383
A decrease in cardiovascular risk factors in healthy 40-year-old Swedish men between 1980-1983 and 1991-1992.
Tornvall P; Båvenholm P; Hellénius ML; Karpe F; Regnström J; de Faire U
Article: JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH. 1996;50(2):131-136
Effect of diet and physical exercise intervention programmes on coronary heart disease risk in smoking and non-smoking men in Sweden
Naslund GK; Fredrikson M; Hellenius ML; deFaire U
Article: JOURNAL OF INTERNAL MEDICINE. 1995;238(2):121-130
EFFECTS ON GLUCOSE-TOLERANCE, INSULIN-SECRETION, INSULIN-LIKE GROWTH-FACTOR-1 AND ITS BINDING-PROTEIN, IGFBP-1, IN A RANDOMIZED CONTROLLED DIET AND EXERCISE STUDY IN HEALTHY, MIDDLE-AGED MEN
HELLENIUS MLB; BRISMAR KE; BERGLUND BH; DEFAIRE UH
Article: QUALITY OF LIFE RESEARCH. 1995;4(1):13-20
QUALITY-OF-LIFE IS NOT NEGATIVELY AFFECTED BY DIET AND EXERCISE INTERVENTION IN HEALTHY-MEN WITH CARDIOVASCULAR RISK-FACTORS
HELLENIUS ML; DAHLOF C; ABERG H; KRAKAU I; DEFAIRE U
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Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2023;293(5):528-530
Lessons from the CORDIOPREV study-Lifestyle interventions still needed to improve cardiometabolic health in patients with coronary heart disease
Hellenius M-L; Cederholm T
Editorial comment: EUROPEAN HEART JOURNAL. 2022;43(21):2076-2077
Encouraging physical activity amongst older adults; where should we stand?
Hellenius M-L
Review: PLOS MEDICINE. 2021;18(9):e1003763
Biomarkers of dairy fat intake, incident cardiovascular disease, and all-cause mortality: A cohort study, systematic review, and meta-analysis
Trieu K; Bhat S; Dai Z; Leander K; Gigante B; Qian F; Korat AVA; Sun Q; Pan X-F; Laguzzi F; Cederholm T; de Faire U; Hellenius M-L; Wu JHY; Riserus U; Marklund M
Review: LAKARTIDNINGEN. 2016;113:DYMA
[The importance of food for aging and longevity. Food composition, oxidative stress and weight are important factors].
Cederholm T; Hellénius M-L
Letter: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2014;173(3):560
Response to: Modifiable lifestyle risks, cardiovascular disease, and all-cause mortality
Carlsson AC; Wandell PE; Gigante B; Leander K; Hellenius M-L; de Faire U
Editorial comment: BRITISH JOURNAL OF SPORTS MEDICINE. 2011;45(3):158
Physical activity as medicine: time to translate evidence into clinical practice
Hellenius M-L; Sundberg CJ
Editorial comment: BRITISH JOURNAL OF SPORTS MEDICINE. 2010;44(12):834-835
Are we facing a new paradigm of inactivity physiology?
Ekblom-Bak E; Hellenius M-L; Ekblom B
Review: LAKARTIDNINGEN. 2010;107(9):587-588
[Less sitting as important as increased physical activity].
Ekblom-Bak E; Ekblom B; Hellénius M-L
Published conference paper: JOURNAL OF CARDIOVASCULAR RISK. 2009;16(1):80-84
Beneficial effects of individualized physical activity on prescription on body composition and cardiometabolic risk factors: results from a randomized controlled trial
Kallings LV; Johnson JS; Fisher RM; de Faire U; Stahle A; Hemmingsson E; Hellenius M-L
Published conference paper: JOURNAL OF CARDIOVASCULAR RISK. 2008;15(3):258-262
Sex differences in risk factor control off treated hypertensives:: a national primary healthcare-based study in Sweden
Journath G; Hellenius M-L; Petersson U; Theobald H; Nilsson PM
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2008;9(1):82
GENDER DIFFERENCES IN RISK FACTOR CONTROL OF PATIENTS ON LIPID LOWERING DRUGS, A NATIONAL PRIMARY HEALTH CARE STUDY
Journath G; Collijn E; Nilsson P; Hellenius M-L
Review: LAKARTIDNINGEN. 2007;104(51-52):3857-3861
[The metabolic syndrome threatens public health. Increased physical activity the best cure].
Hellénius M-L; Rauramaa R
Review: LAKARTIDNINGEN. 2007;104(37):2592-2596
[Methods for physical activity promotion. A systematic literature review from SBU].
Hellénius M-L; Eckerlund I
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2007;8(1):177
Prevalence of left ventricular hypertrophy and its association to variables of the metabolic syndrome in 60-year old men and women
Halldin M; de Faire U; Hellenius M-L
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2007;8(1):116
Endothelial activity is related to diet and components of the metabolic syndrome, but not to advanced glycation end-products in healthy swedish men
Sjogren P; Basta G; de Caterina R; Rosell M; Basu S; Silveira A; de Faire U; Vessby B; Hamsten A; Hellenius ML; Fisher RM
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2007;8(1):60-61
Human evidence for the involvement of INSIG-2 in the adipose tissue metabolism
Krapivner S; Popov S; Chemogubova E; Hellenius M-L; Fisher R; Hamsten A; van't Hooft F
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2007;8(1):3
Stearoyl coa desaturase (SCD) activity in human adipose tissue is increased in the metabolic syndrome
Fisher RM; Sjogren P; Rose M; Hamsten A; Vessby B; Hellenius M-L
Letter: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2006;26(4):E31-E32
Oxidized LDL and the metabolic syndrome - In response
Sjogren P; Hamsten A; Hellenius ML; Fisher RM
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):231
Relationships between autoantibodies against modified LDL and advanced glycation end-products in clinically healthy men
Sjögren P; Fredrikson GN; Basta G; Hamsten A; Nilsson J; Hellenius ML; De Caterina R; Fisher RM
Published conference paper: JOURNAL OF NUTRITION. 2004;134(7):1729-1735
Milk-derived fatty acids are associated with a more favorable LDL particle size distribution in healthy men
Sjogren P; Rosell M; Skoglund-Andersson C; Zdravkovic S; Vessby B; de Faire U; Hamsten A; Hellenius ML; Fisher RM
Review: LAKARTIDNINGEN. 2001;98(39):4188-4190
[Also elderly patients with hyperlipidemia and coronary disease need lipid lowering agents].
Hellénius ML
Review: LAKARTIDNINGEN. 1999;96(30-31):3343-3346
[Prescribed exercise can help the patient to change his habits].
Hellénius ML; Arborelius E
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Employments

Professor Emeritus/Emerita, Department of Medicine, Karolinska Institutet, 2022-2025
Professor/Senior Physician, Department of Medicine, Karolinska Institutet, 2010-2019
Professor/District Medical Officer, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2006-2009
Researcher, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2005-2006
Researcher, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 2004-2005

Degrees and Education

Docent, Karolinska Institutet, 1999

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