Lena Backlund

Lena Backlund

Affiliated to Research
Visiting address: CMM, Karolinska universitetssjukhuset L8:00, 17176 Stockholm
Postal address: K1 Molekylär medicin och kirurgi, K1 MMK Translationell psykiatri, 171 76 Stockholm
Part of:

Research

  • Effective Lithium (Li)-prophylaxis is the most important factor for a good
    prognosis in bipolar disorder (BD). However, 40-50% do not respond on
    Li-treatment and there is a lack of biomarkers for Li-response. We aim to
    develop biological markers for Li-response to use for a more targeted drug
    choice already at onset of BD. Based on previous findings we hypothesize that
    a high telomerase activity and/or epigenetic changes early after
    Li-introduction can be used as such biomarkers.
    Different genetic variants can be associated with a good Li-response. We have
    assessed more than 700 patients for Lithium-response, which constitute a
    large part of the material in the international project ConLiGen. There are
    also other molecular genetic alternatives.
    Telomeres (TL) are DNA nucleoprotein complexes that form the ends of
    chromosomes and erode progressively with each cell division, which means that
    the telomeric length declines with age, stress and disorders such as
    depression. In contrast, physical exercise and effective treatment can
    prevent TL shortening and rebuild TL s through telomerase activity.
    Antidepressants have been found to protect against blood leucocyte TL
    shortening. In this project we have found that Li-treated bipolar patients
    had 35% longer leucocyte telomeres compared with controls and in line with
    findings in unipolar depressive episodes TL was negatively associated with an
    increasing number of depressive episodes, see selected publications.
    Epigenetic changes are reversible changes in gene expression but not in the
    DNA sequence, fundamental to the physiological processes that control the
    genetic activity. These changes may be caused by the influence of
    environmental factors or disease state, but also contributes to the
    likelihood that the disease arises and precedes.
    In a prospective study we follow telomere length, telomerase activity and
    epigenetic changes associated with Li-response. Positive findings from this
    project, might be of great importance in the clinical everyday life, save a
    great deal of suffering, many lives and reduce the high costs for society.

Articles

  • Article: TRANSLATIONAL PSYCHIATRY. 2024;14(1):109
    Ou AH; Rosenthal SB; Adli M; Akiyama K; Akula N; Alda M; Amare AT; Ardau R; Arias B; Aubry J-M; Backlund L; Bauer M; Baune BT; Bellivier F; Benabarre A; Bengesser S; Bhattacharjee AK; Biernacka JM; Cervantes P; Chen G-B; Chen H-C; Chillotti C; Cichon S; Clark SR; Colom F; Cousins DA; Cruceanu C; Czerski PM; Dantas CR; Dayer A; Del Zompo M; Degenhardt F; DePaulo JR; Etain B; Falkai P; Fellendorf FT; Ferensztajn-Rochowiak E; Forstner AJ; Frisen L; Frye MA; Fullerton JM; Gard S; Garnham JS; Goes FS; Grigoroiu-Serbanescu M; Grof P; Gruber O; Hashimoto R; Hauser J; Heilbronner U; Herms S; Hoffmann P; Hofmann A; Hou L; Jamain S; Jimenez E; Kahn J-P; Kassem L; Kato T; Kittel-Schneider S; Koenig B; Kuo P-H; Kusumi I; Lackner N; Laje G; Landen M; Lavebratt C; Leboyer M; Leckband SG; Lopez Jaramillo CA; MacQueen G; Maj M; Manchia M; Marie-Claire C; Martinsson L; Mattheisen M; McCarthy MJ; McElroy SL; McMahon FJ; Mitchell PB; Mitjans M; Mondimore FM; Monteleone P; Nievergelt CM; Noethen MM; Novak T; Oesby U; Ozaki N; Papiol S; Perlis RH; Pisanu C; Potash JB; Pfennig A; Reich-Erkelenz D; Reif A; Reininghaus EZ; Rietschel M; Rouleau GA; Rybakowski JK; Schalling M; Schofield PR; Schubert KO; Schulze TG; Schweizer BW; Seemueller F; Severino G; Shekhtman T; Shilling PD; Shimoda K; Simhandl C; Slaney CM; Squassina A; Stamm T; Stopkova P; Tighe SK; Tortorella A; Turecki G; Vieta E; Volkert J; Witt S; Wray NR; Wright A; Young LT; Zandi PP; Kelsoe JR
  • Article: MOLECULAR PSYCHIATRY. 2023;28(12):5251-5261
    Amare AT; Thalamuthu A; Schubert KO; Fullerton JM; Ahmed M; Hartmann S; Papiol S; Heilbronner U; Degenhardt F; Tekola-Ayele F; Hou L; Hsu Y-H; Shekhtman T; Adli M; Akula N; Akiyama K; Ardau R; Arias B; Aubry J-M; Hasler R; Richard-Lepouriel H; Perroud N; Backlund L; Bhattacharjee AK; Bellivier F; Benabarre A; Bengesser S; Biernacka JM; Birner A; Marie-Claire C; Cervantes P; Chen H-C; Chillotti C; Cichon S; Cruceanu C; Czerski PM; Dalkner N; Del Zompo M; DePaulo JR; Etain B; Jamain S; Falkai P; Forstner AJ; Frisen L; Frye MA; Gard S; Garnham JS; Goes FS; Grigoroiu-Serbanescu M; Fallgatter AJ; Stegmaier S; Ethofer T; Biere S; Petrova K; Schuster C; Adorjan K; Budde M; Heilbronner M; Kalman JL; Kohshour MO; Reich-Erkelenz D; Schaupp SK; Schulte EC; Senner F; Vogl T; Anghelescu I-G; Arolt V; Dannlowski U; Dietrich D; Figge C; Jaeger M; Lang FU; Juckel G; Konrad C; Reimer J; Schmauss M; Schmitt A; Spitzer C; von Hagen M; Wiltfang J; Zimmermann J; Andlauer TFM; Fischer A; Bermpohl F; Ritter P; Matura S; Gryaznova A; Falkenberg I; Yildiz C; Kircher T; Schmidt J; Koch M; Gade K; Trost S; Haussleiter IS; Lambert M; Rohenkohl AC; Kraft V; Grof P; Hashimoto R; Hauser J; Herms S; Hoffmann P; Jimenez E; Kahn J-P; Kassem L; Kuo P-H; Kato T; Kelsoe J; Kittel-Schneider S; Ferensztajn-Rochowiak E; Koenig B; Kusumi I; Laje G; Landen M; Lavebratt C; Leboyer M; Leckband SG; Tortorella A; Manchia M; Martinsson L; McCarthy MJ; McElroy S; Colom F; Millischer V; Mitjans M; Mondimore FM; Monteleone P; Nievergelt CM; Noethen MM; Novak T; O'Donovan C; Ozaki N; Pfennig A; Pisanu C; Potash JB; Reif A; Reininghaus E; Rouleau GA; Rybakowski JK; Schalling M; Schofield PR; Schweizer BW; Severino G; Shilling PD; Shimoda K; Simhandl C; Slaney CM; Squassina A; Stamm T; Stopkova P; Maj M; Turecki G; Vieta E; Veeh J; Witt SH; Wright A; Zandi PP; Mitchell PB; Bauer M; Alda M; Rietschel M; McMahon FJ; Schulze TG; Clark SR; Baune BT
  • Article: BIPOLAR DISORDERS. 2023;25(5):391-401
    Ponzer K; Millischer V; Schalling M; Gissler M; Lavebratt C; Backlund L
  • Article: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2023;227:115269
    Wikstrom F; Olsson C; Palm B; Roxhed N; Backlund L; Schalling M; Beck O
  • Article: SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY. 2023;58(4):537-545
    Wikstrom F; Zeberg H; Mayston R; Backlund L; Fekadu A
  • Article: LANCET PSYCHIATRY. 2022;9(6):447-457
    Millischer V; Matheson GJ; Bergen SE; Coombes BJ; Ponzer K; Wikstrom F; Jagiello K; Lundberg M; Stenvinkel P; Biernacka JM; Breuer O; Martinsson L; Landen M; Backlund L; Lavebratt C; Schalling M
  • Article: BRITISH JOURNAL OF PSYCHIATRY. 2022;220(4):1-10
    Cearns M; Amare AT; Schubert KO; Thalamuthu A; Frank J; Streit F; Adli M; Akula N; Akiyama K; Ardau R; Arias B; Aubry J-M; Backlund L; Bhattacharjee AK; Bellivier F; Benabarre A; Bengesser S; Biernacka JM; Birner A; Brichant-Petitjean C; Cervantes P; Chen H-C; Chillotti C; Cichon S; Cruceanu C; Czerski PM; Dalkner N; Dayer A; Degenhardt F; Del Zompo M; De Paulo JR; Etain B; Falkai P; Forstner AJ; Frisen L; Frye MA; Fullerton JM; Gard S; Garnham JS; Goes FS; Grigoroiu-Serbanescu M; Grof P; Hashimoto R; Hauser J; Heilbronner U; Herms S; Hoffmann P; Hofmann A; Hou L; Hsu YH; Jamain S; Jimenez E; Kahn J-P; Kassem L; Kuo P-H; Kato T; Kelsoe J; Kittel-Schneider S; Kliwicki S; Konig B; Kusumi I; Laje G; Landen M; Lavebratt C; Leboyer M; Leckband SG; Maj M; Manchia M; Martinsson L; McCarthy MJ; McElroy S; Colom F; Mitjans M; Mondimore FM; Monteleone P; Nievergelt CM; Nothen MM; Novak T; O'Donovan C; Ozaki N; Millischer V; Papiol S; Pfennig A; Pisanu C; Potash JB; Reif A; Reininghaus E; Rouleau GA; Rybakowski JK; Schalling M; Schofield PR; Schweizer BW; Severino G; Shekhtman T; Shilling PD; Shimoda K; Simhandl C; Slaney CM; Squassina A; Stamm T; Stopkova P; Tekola-Ayele F; Tortorella A; Turecki G; Veeh J; Vieta E; Witt SH; Roberts G; Zandi PP; Alda M; Bauer M; McMahon FJ; Mitchell PB; Schulze TG; Rietschel M; Clark SR; Baune BT
  • Article: COMPLEX PSYCHIATRY. 2021;7(3-4):80-89
    Coombes BJ; Millischer V; Batzler A; Larrabee B; Hou L; Papiol S; Heilbronner U; Adli M; Akiyama K; Akula N; Amare AT; Ardau R; Arias B; Aubry J-M; Backlund L; Bauer M; Baune BT; Bellivier F; Benabarre A; Bengesser S; Bhattacharjee AK; Cervantes P; Chen H-C; Chillotti C; Cichon S; Clark SR; Colom F; Cruceanu C; Czerski PM; Dalkner N; Degenhardt F; Del Zompo M; DePaulo JR; Étain B; Falkai P; Ferensztajn-Rochowiak E; Forstner AJ; Frisen L; Gard S; Garnham JS; Goes FS; Grigoroiu-Serbanescu M; Grof P; Hashimoto R; Hauser J; Herms S; Hoffmann P; Jamain S; Jiménez E; Kahn J-P; Kassem L; Kato T; Kelsoe JR; Kittel-Schneider S; König B; Kuo P-H; Kusumi I; Laje G; Landén M; Lavebratt C; Leboyer M; Leckband SG; Maj M; Manchia M; Martinsson L; McCarthy MJ; McElroy SL; Mitchell PB; Mitjans M; Mondimore FM; Monteleone P; Nievergelt CM; Nöthen MM; Novák T; O'Donovan C; Osby U; Ozaki N; Pfennig A; Pisanu C; Potash JB; Reif A; Reininghaus E; Rietschel M; Rouleau GA; Rybakowski JK; Schalling M; Schofield PR; Schubert KO; Schweizer BW; Severino G; Shekhtman T; Shilling PD; Shimoda K; Simhandl C; Slaney CM; Squassina A; Stamm T; Stopkova P; Tortorella A; Turecki G; Vieta E; Witt SH; Zandi PP; Fullerton JM; Alda M; Frye MA; Schulze TG; McMahon FJ; Biernacka JM
  • Article: TRANSLATIONAL PSYCHIATRY. 2021;11(1):606
    Schubert KO; Thalamuthu A; Amare AT; Frank J; Streit F; Adl M; Akula N; Akiyama K; Ardau R; Arias B; Aubry J-M; Backlund L; Bhattacharjee AK; Bellivier F; Benabarre A; Bengesser S; Biernacka JM; Birner A; Marie-Claire C; Cearns M; Cervantes P; Chen H-C; Chillotti C; Cichon S; Clark SR; Cruceanu C; Czerski PM; Dalkner N; Dayer A; Degenhardt F; Del Zompo M; DePaulo JR; Etain B; Falkai P; Forstner AJ; Frisen L; Frye MA; Fullerton JM; Gard S; Garnham JS; Goes FS; Grigoroiu-Serbanescu M; Grof P; Hashimoto R; Hauser J; Heilbronner U; Herms S; Hoffmann P; Hou L; Hsu Y-H; Jamain S; Jimenez E; Kahn J-P; Kassem L; Kuo P-H; Kato T; Kelsoe J; Kittel-Schneider S; Ferensztajn-Rochowiak E; Koenig B; Kusumi I; Laje G; Landen M; Lavebratt C; Leboyer M; Leckband SG; Maj M; Manchia M; Martinsson L; McCarthy MJ; McElroy S; Colom F; Mitjans M; Mondimore FM; Monteleone P; Nievergelt CM; Noethen MM; Novak T; O'Donovan C; Ozaki N; Oesby U; Papiol S; Pfennig A; Pisanu C; Potash JB; Reif A; Reininghaus E; Rouleau GA; Rybakowski JK; Schalling M; Schofield PR; Schweizer BW; Severino G; Shekhtman T; Shilling PD; Shimoda K; Simhandl C; Slaney CM; Squassina A; Stamm T; Stopkova P; Tekola-Ayele F; Tortorella A; Turecki G; Veeh J; Vieta E; Witt SH; Roberts G; Zandi PP; Alda M; Bauer M; McMahon FJ; Mitchell PB; Schulze TG; Rietschel M; Baune BT
  • Article: SCIENTIFIC REPORTS. 2021;11(1):17823
    Le Clerc S; Lombardi L; Baune BT; Amare AT; Schubert KO; Hou L; Clark SR; Papiol S; Cearns M; Heilbronner U; Degenhardt F; Tekola-Ayele F; Hsu Y-H; Shekhtman T; Adli M; Akula N; Akiyama K; Ardau R; Arias B; Aubry J-M; Backlund L; Bhattacharjee AK; Bellivier F; Benabarre A; Bengesser S; Biernacka JM; Birner A; Brichant-Petitjean C; Cervantes P; Chen H-C; Chillotti C; Cichon S; Cruceanu C; Czerski PM; Dalkner N; Dayer A; Del Zompo M; DePaulo JR; Etain B; Jamain S; Falkai P; Forstner AJ; Frisen L; Frye MA; Fullerton JM; Gard S; Garnham JS; Goes FS; Grigoroiu-Serbanescu M; Grof P; Hashimoto R; Hauser J; Herms S; Hofmann P; Jimenez E; Kahn J-P; Kassem L; Kuo P-H; Kato T; Kelsoe JR; Kittel-Schneider S; Ferensztajn-Rochowiak E; Koenig B; Kusumi I; Laje G; Landen M; Lavebratt C; Leckband S; Tortorella A; Manchia M; Martinsson L; McCarthy MJ; McElroy SL; Colom F; Millischer V; Mitjans M; Mondimore FM; Monteleone P; Nievergelt CM; Noethen MM; Novak T; O'Donovan C; Ozaki N; Osby U; Pfennig A; Potash JB; Reif A; Reininghaus E; Rouleau GA; Rybakowski JK; Schalling M; Schofeld PR; Schweizer BW; Severino G; Shilling PD; Shimoda K; Simhandl C; Slaney CM; Pisanu C; Squassina A; Stamm T; Stopkova P; Maj M; Turecki G; Vieta E; Veeh J; Witt SH; Wright A; Zandi PP; Mitchell PB; Bauer M; Alda M; Rietschel M; McMahon FJ; Schulze TG; Boukouaci W; Richard J-R; Le Corvoisier P; Barrau C; Zagury J-F; Leboyer M; Tamouza R
  • Article: NATURE GENETICS. 2021;53(6):817-829
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  • Article: MOLECULAR PSYCHIATRY. 2021;26(6):2457-2470
    Amare AT; Schubert KO; Hou L; Clark SR; Papiol S; Cearns M; Heilbronner U; Degenhardt F; Tekola-Ayele F; Hsu Y-H; Shekhtman T; AdIi M; Akula N; Akiyama K; Ardau R; Arias B; Aubry J-M; Backlund L; Bhattacharjee K; Bellivier F; Benabarre A; Bengesser S; Biernacka JM; Birner A; Brichant-Petitjean C; Cervantes P; Chen H-C; Chillotti C; Cichon S; Cruceanu C; Czerski PM; Dalkner N; Dayer A; Del Zompo M; DePaulo JR; Etain B; Jamain S; Falkai P; Forstner AJ; Frisen L; Frye MA; Fullerton JM; Gard S; Garnham JS; Goes FS; Grigoroiu-Serbanescu M; Grof P; Hashimoto R; Hauser J; Herms S; Hoffmann P; Hofmann A; Jimenez E; Kahn J-P; Kassem L; Kuo P-H; Kato T; Kelsoe JR; Kittel-Schneider S; Kliwicki S; Koenig B; Kusumi I; Laje G; Landen M; Lavebratt C; Leboyer M; Leckband SG; Tortorella A; Manchia M; Martinsson L; McCarthy MJ; McElroy SL; Colom F; Mitjans M; Mondimore FM; Monteleone P; Nievergelt CM; Noethen MM; Novak T; O'Donovan C; Ozaki N; Osby U; Pfennig A; Potash JB; Reif A; Reininghaus E; Rouleau GA; Rybakowski JK; Schalling M; Schofield PR; Schweizer BW; Severino G; Shilling PD; Shimoda K; Simhandl C; Slaney CM; Squassina A; Stamm T; Stopkova P; Maj M; Turecki G; Vieta E; Veeh J; Witt SH; Wright A; Zandi PP; Mitchell PB; Bauer M; Alda M; Rietschel M; McMahon FJ; Schulze TG; Baune BT
  • Article: SCIENTIFIC REPORTS. 2021;11(1):1155
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  • Article: BIPOLAR DISORDERS. 2020;22(3):255-265
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  • Article: PSYCHIATRY RESEARCH. 2020;284:112677
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  • Article: CELL. 2019;179(7):1469-1482.e11
    Lee PH; Anttila V; Won H; Feng Y-CA; Rosenthal J; Zhu Z; Tucker-Drob EM; Nivard MG; Grotzinger AD; Posthuma D; Wang MM-J; Yu D; Stahl EA; Walters R-MK; Anney RJL; Duncan LE; Ge T; Adolfsson R; Banaschewski T; Belangero S; Cook EH; Coppola G; Derks EM; Hoekstra PJ; Kaprio J; Keski-Rahkonen A; Kirov G; Kranzler HR; Luykx JJ; Rohde LA; Zai CC; Agerbo E; Arranz MJ; Asherson P; Baekvad-Hansen M; Baldursson G; Bellgrove M; Belliveau RAJ; Buitelaar J; Burton CL; Bybjerg-Grauholm J; Casas M; Cerrato F; Chambert K; Churchhouse C; Gormand B; Crosbie J; Dalsgaard S; Demontis D; Doyle AE; Dumont A; Elia J; Grove J; Gudmundsson OO; Haavik J; Hakonarson H; Hansen CS; Hartman CA; Hawi Z; Hervas A; Hougaard DM; Howrigan DP; Huang H; Kuntsi J; Langley K; Lesch K-P; Leung PWL; Loo SK; Martin J; Martin AR; McGough JJ; Medland SE; Moran JL; Mors O; Mortensen PB; Oades RD; Palmer DS; Pedersen CB; Pedersen MG; Peters T; Poterba T; Poulsen JB; Ramos-Quiroga JA; Reif A; Ribases M; Rothenberger A; Rovira P; Sanchez-Mora C; Satterstrom FK; Schachar R; Artigas MS; Steinberg S; Stefansson H; Turley P; Walters GB; Werge T; Zayats T; Arking DE; Bettella F; Buxbaum JD; Christensen JH; Collins RL; Coon H; De Rubeis S; Delorme R; Grice DE; Hansen TF; Holmans PA; Hope S; Hultman CM; Klei L; Ladd-Acosta C; Magnusson P; NrIand T; Nyegaard M; Pinto D; Qvist P; Rehnstrom K; Reichenberg A; Reichert J; Roeder K; Rouleau GA; Saemundsen E; Sanders SJ; Sandin S; St Pourcain B; Stefansson K; Sutcliffe JS; Talkowski ME; Weiss LA; Willsey AJ; Agartz I; Akil H; Albani D; Alda M; Als TD; Anjorin A; Backlund L; Bass N; Bauer M; Baune BT; Bellivier F; Bergen SE; Berrettini WH; Biernacka JM; Blackwood DHR; Boen E; Budde M; Bunney W; Burmeister M; Byerley W; Byrne EM; Cichon S; Clarke T-K; Coleman JRI; Craddock N; Curtis D; Czerski PM; Dale AM; Dalkner N; Dannlowski U; Degenhardt F; Di Florio A; Elvsashagen T; Etain B; Fischer SB; Forstner AJ; Forty L; Frank J; Frye M; Fullerton JM; Gade K; Gaspar HA; Gershon ES; Gill M; Goes FS; Gordon SD; Gordon-Smith K; Green MJ; Greenwood TA; Grigoroiu-Serbanescu M; Guzman-Parra J; Hauser J; Hautzinger M; Heilbronner U; Herms S; Hoffmann P; Holland D; Jamain S; Jones I; Jones LA; Kandaswamy R; Kelsoe JR; Kennedy JL; Joachim OK; Kittel-Schneider S; Kogevinas M; Koller AC; Lavebratt C; Lewis CM; Li QS; Lissowska J; Loohuis LMO; Lucae S; Maaser A; Malt UF; Martin NG; Martinsson L; McElroy SL; McMahon FJ; McQuillin A; Melle I; Metspalu A; Millischer V; Mitchell PB; Montgomery GW; Morken G; Morris DW; Mueller-Myhsok B; Mullins N; Myers RM; Nievergelt CM; Nordentoft M; Adolfsson AN; Nothen MM; Ophoff RA; Owen MJ; Paciga SA; Pato CN; Pato MT; Perlis RH; Perry A; Potash JB; Reinbold CS; Rietschel M; Rivera M; Roberson M; Schalling M; Schofield PR; Schulze TG; Scott LJ; Serretti A; Sigurdsson E; Smeland OB; Stordal E; Streit F; Strohmaier J; Thorgeirsson TE; Treutlein J; Turecki G; Vaaler AE; Vieta E; Vincent JB; Wang Y; Witt SH; Zandi P; Adan RAH; Alfredsson L; Ando T; Aschauer H; Baker JH; Bencko V; Bergen AW; Birgegard A; Perica VB; Brandt H; Burghardt R; Carlberg L; Cassina M; Clementi M; Courtet P; Crawford S; Crow S; Crowley JJ; Danner UN; Davis OSP; Degortes D; DeSocio JE; Dick DM; Dina C; Docampo E; Egberts K; Ehrlich S; Espeseth T; Fernandez-Aranda F; Fichter MM; Foretova L; Forzan M; Gambaro G; Giegling I; Gonidakis F; Gorwood P; Mayora MG; Guo Y; Halmi KA; Herpertz-Dahlmann; Herzog W; Hinney A; Imgart H; Jimenez-Murcia S; Johnson C; Jordan J; Julia A; Kaminska D; Karhunen L; Karwautz A; Kas MJH; Kaye WH; Kennedy MA; Kim Y-R; Klareskog L; Klump KL; Knudsen GPS; Landen M; Le Hellard S; Levitan RD; Li D; Lichtenstein P; Maj M; Marsal S; McDevitt S; Mitchell J; Monteleone P; Monteleone AM; Munn-Chernoff MA; Nacmias B; Navratilova M; O'Toole JK; Padyukov L; Pantel J; Papezova H; Rabionet R; Raevuori A; Ramoz N; Reichborn-Kjennerud T; Ricca V; Roberts M; Rujescu D; Rybakowski F; Scherag A; Schmidt U; Seitz J; Slachtova L; Landt MCTS-O; Slopien A; Sorbi S; Southam L; Strober M; Tortorella A; Tozzi F; Treasure J; Tziouvas K; van Elburg AA; Wade TD; Wagner G; Walton E; Watson HJ; Wichmann H-E; Woodside DB; Zeggini E; Zerwas S; Zipfel S; Adams MJ; Andlauer TFM; Berger K; Binder EB; Boomsma DI; Castelao E; Colodro-Conde L; Direk N; Docherty AR; Domenici E; Domschke K; Dunn EC; Foo JC; de Geus EJC; Grabe HJ; Hamilton SP; Horn C; Hottenga J-J; Howard D; Sing M; Kloiber S; Levinson DF; Lewis G; Magnusson PKE; Mbarek H; Middeldorp CM; Mostafavi S; Nyholt DR; Penninx BWJH; Peterson RE; Pistis G; Porteous DJ; Preisig M; Quiroz JA; Schaefer C; Schulte EC; Shi J; Smith DJ; Thomson PA; Tiemeier H; Uher R; van der Auwera S; Weissman MM; Alexander M; Begemann M; Bramon E; Buccola NG; Cairns MJ; Campion D; Carr VJ; Cloninger CR; Cohen D; Collier DA; Corvin A; DeLisi LE; Donohoe G; Dudbridge F; Duan J; Freedman R; Gejman PV; Golimbet V; Godard S; Ehrenreich H; Hartmann AM; Henskens FA; Ikeda M; Iwata N; Jablensky AV; Joa I; Jonsson EG; Kelly BJ; Knight J; Konte B; Laurent-Levinson C; Lee J; Lencz T; Lerer B; Loughland CM; Malhotra AK; Mallet J; McDonald C; Mitjans M; Mowry BJ; Murphy KC; Murray RM; O'Neill FA; Oh S-Y; Palotie A; Pantelis C; Pulver AE; Petryshen TL; Quested DJ; Riley B; Sanders AR; Schall U; Schwab SG; Scott RJ; Sham PC; Silverman JM; Sim K; Steixner AA; Tooney PA; van Os J; Vawter MP; Walsh D; Weiser M; Wildenauer DB; Williams NM; Wormley BK; Zhang F; Androutsos C; Arnold PD; Barr CL; Barta C; Bey K; Bienvenu OJ; Black DW; Brown LW; Budman C; Cath D; Cheon K-A; Ciullo V; Coffey BJ; Cusi D; Davis LK; Denys D; Depienne C; Dietrich A; Eapen V; Falkai P; Fernandez TV; Garcia-Delgar B; Geller DA; Gilbert DL; Grados MA; Greenberg E; Grunblatt E; Hagstrom J; Hanna GL; Hartmann A; Hedderly T; Heiman GA; Heyman I; Hong HJ; Huang A; Huyser C; Ibanez-Gomez L; Khramtsova EA; Kim YK; Kim Y-S; King RA; Koh Y-J; Konstantinidis A; Kook S; Kuperman S; Leventhal BL; Lochner C; Ludolph AG; Madruga-Garrido M; Malaty I; Maras A; McCracken JT; Meijer IA; Mir P; Morer A; Mueller-Vahl KR; Munchau A; Murphy TL; Naarden A; Nagy P; Nestadt G; Nestadt PS; Nicolini H; Nurmi EL; Okun MS; Paschou P; Piras F; Piras F; Pittenger C; Plessen KJ; Richter MA; Rizzo R; Robertson M; Roessner V; Ruhrmann S; Samuels JF; Sandor P; Schlogelhofer M; Shin E-Y; Singer H; Song D-H; Song J; Spalletta G; Stein DJ; Stewart SE; Storch EA; Stranger B; Stuhrmann M; Tarnok Z; Tischfield JA; Tubing J; Visscher F; Vulink N; Wagner M; Walitza S; Wanderer S; Woods M; Worbe Y; Zai G; Zinner SH; Sullivan PF; Franke B; Daly MJ; Bulik CM; McIntosh AM; O'Donovan MC; Zheutlin A; Andreassen OA; Borglum AD; Breen G; Edenberg HJ; Fanous AH; Faraone SV; Gelernter J; Mathews CA; Mattheisen M; Mitchell KS; Neale MC; Nurnberger JI; Ripke S; Santangelo SL; Scharf JM; Stein MB; Thornton LM; Walters JTR; Wray NR; Geschwind DH; Neale BM; Kendler KS; Smoller JW
  • Article: BIOLOGICAL PSYCHIATRY. 2019;86(2):110-119
    Charney AW; Stahl EA; Green EK; Chen C-Y; Moran JL; Chambert K; Belliveau RAJ; Forty L; Gordon-Smith K; Lee PH; Bromet EJ; Buckley PF; Escamilla MA; Fanous AH; Fochtmann LJ; Lehrer DS; Malaspina D; Marder SR; Morley CP; Nicolini H; Perkins DO; Rakofsky JJ; Rapaport MH; Medeiros H; Sobell JL; Backlund L; Bergen SE; Jureus A; Schalling M; Lichtenstein P; Knowles JA; Burdick KE; Jones I; Jones LA; Hultman CM; Perlis R; Purcell SM; McCarroll SA; Pato CN; Pato MT; Di Florio A; Craddock N; Landen M; Smoller JW; Ruderfer DM; Sklar P
  • Article: COGNITIVE BEHAVIOUR THERAPY. 2019;48(4):285-299
    Vernmark K; Hesser H; Topooco N; Berger T; Riper H; Luuk L; Backlund L; Carlbring P; Andersson G
  • Article: TRANSLATIONAL PSYCHIATRY. 2019;9(1):149
    Veldic M; Millischer V; Port JD; Ho AM-C; Jia Y-F; Geske JR; Biernacka JM; Backlund L; McElroy SL; Bond DJ; Villaescusa JC; Skime M; Choi D-S; Lavebratt C; Schalling M; Frye MA
  • Article: NATURE GENETICS. 2019;51(5):793-803
    Stahl EA; Breen G; Forstner AJ; McQuillin A; Ripke S; Trubetskoy V; Mattheisen M; Wang Y; Coleman JRI; Gaspar HA; de Leeuw CA; Steinberg S; Pavlides JMW; Trzaskowski M; Byrne EM; Pers TH; Holmans PA; Richards AL; Abbott L; Agerbo E; Akil H; Albani D; Alliey-Rodriguez N; Als TD; Anjorin A; Antilla V; Awasthi S; Badner JA; Bækvad-Hansen M; Barchas JD; Bass N; Bauer M; Belliveau R; Bergen SE; Pedersen CB; Bøen E; Boks MP; Boocock J; Budde M; Bunney W; Burmeister M; Bybjerg-Grauholm J; Byerley W; Casas M; Cerrato F; Cervantes P; Chambert K; Charney AW; Chen D; Churchhouse C; Clarke T-K; Coryell W; Craig DW; Cruceanu C; Curtis D; Czerski PM; Dale AM; de Jong S; Degenhardt F; Del-Favero J; DePaulo JR; Djurovic S; Dobbyn AL; Dumont A; Elvsåshagen T; Escott-Price V; Fan CC; Fischer SB; Flickinger M; Foroud TM; Forty L; Frank J; Fraser C; Freimer NB; Frisén L; Gade K; Gage D; Garnham J; Giambartolomei C; Pedersen MG; Goldstein J; Gordon SD; Gordon-Smith K; Green EK; Green MJ; Greenwood TA; Grove J; Guan W; Guzman-Parra J; Hamshere ML; Hautzinger M; Heilbronner U; Herms S; Hipolito M; Hoffmann P; Holland D; Huckins L; Jamain S; Johnson JS; Juréus A; Kandaswamy R; Karlsson R; Kennedy JL; Kittel-Schneider S; Knowles JA; Kogevinas M; Koller AC; Kupka R; Lavebratt C; Lawrence J; Lawson WB; Leber M; Lee PH; Levy SE; Li JZ; Liu C; Lucae S; Maaser A; MacIntyre DJ; Mahon PB; Maier W; Martinsson L; McCarroll S; McGuffin P; McInnis MG; McKay JD; Medeiros H; Medland SE; Meng F; Milani L; Montgomery GW; Morris DW; Mühleisen TW; Mullins N; Nguyen H; Nievergelt CM; Adolfsson AN; Nwulia EA; O'Donovan C; Loohuis LMO; Ori APS; Oruc L; Ösby U; Perlis RH; Perry A; Pfennig A; Potash JB; Purcell SM; Regeer EJ; Reif A; Reinbold CS; Rice JP; Rivas F; Rivera M; Roussos P; Ruderfer DM; Ryu E; Sánchez-Mora C; Schatzberg AF; Scheftner WA; Schork NJ; Shannon Weickert C; Shehktman T; Shilling PD; Sigurdsson E; Slaney C; Smeland OB; Sobell JL; Søholm Hansen C; Spijker AT; St Clair D; Steffens M; Strauss JS; Streit F; Strohmaier J; Szelinger S; Thompson RC; Thorgeirsson TE; Treutlein J; Vedder H; Wang W; Watson SJ; Weickert TW; Witt SH; Xi S; Xu W; Young AH; Zandi P; Zhang P; Zöllner S; eQTLGen Consortium; BIOS Consortium; Adolfsson R; Agartz I; Alda M; Backlund L; Baune BT; Bellivier F; Berrettini WH; Biernacka JM; Blackwood DHR; Boehnke M; Børglum AD; Corvin A; Craddock N; Daly MJ; Dannlowski U; Esko T; Etain B; Frye M; Fullerton JM; Gershon ES; Gill M; Goes F; Grigoroiu-Serbanescu M; Hauser J; Hougaard DM; Hultman CM; Jones I; Jones LA; Kahn RS; Kirov G; Landén M; Leboyer M; Lewis CM; Li QS; Lissowska J; Martin NG; Mayoral F; McElroy SL; McIntosh AM; McMahon FJ; Melle I; Metspalu A; Mitchell PB; Morken G; Mors O; Mortensen PB; Müller-Myhsok B; Myers RM; Neale BM; Nimgaonkar V; Nordentoft M; Nöthen MM; O'Donovan MC; Oedegaard KJ; Owen MJ; Paciga SA; Pato C; Pato MT; Posthuma D; Ramos-Quiroga JA; Ribasés M; Rietschel M; Rouleau GA; Schalling M; Schofield PR; Schulze TG; Serretti A; Smoller JW; Stefansson H; Stefansson K; Stordal E; Sullivan PF; Turecki G; Vaaler AE; Vieta E; Vincent JB; Werge T; Nurnberger JI; Wray NR; Di Florio A; Edenberg HJ; Cichon S; Ophoff RA; Scott LJ; Andreassen OA; Kelsoe J; Sklar P; Bipolar Disorder Working Group of the Psychiatric
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    Kelsoe J; Ou A; Rosenthal S; Adli M; Akiyama K; Akula N; Alda M; Amare AT; Ardau R; Arias B; Aubry J-M; Backlund L; Banzato C; Bauer M; Baune B; Bellivier F; Benabarre A; Bengesser S; Abesh B; Biernacka J; Bui E; Cervantes P; Chen G-B; Chen H-C; Chillotti C; Cichon S; Clark S; Colom F; Cousins D; Cruceanu C; Czerski P; Dantas C; Dayer A; Degenhardt F; DePaulo JR; Etain B; Falkai P; Fellendorf F; Ferensztajn-Rochowiak E; Forstner AJ; Frisen L; Frye M; Fullerton J; Gard S; Garnham J; Goes F; Grigoroiu-Serbanescu M; Grof P; Gruber O; Hashimoto R; Hauser J; Heilbronner U; Herms S; Hoffmann P; Hofmann A; Hou L; Jamain S; Jiménez E; Kahn J-P; Kassem L; Kato T; Kittel-Schneider S; König B; Kuo P-H; Kusumi I; Dalkner N; Laje G; Landén M; Lavebratt C; Leboyer M; Leckband S; Jaramillo CL; MacQueen G; Maj M; Manchia M; Marie-Claire C; Martinsson L; Mattheisen M; McCarthy M; McElroy S; McMahon F; Mitchell P; Mitjans M; Mondimore F; Monteleone P; Nievergelt C; Nöthen M; Novak T; Osby U; Ozaki N; Papiol S; Perlis R; Pfennig A; Potash J; Reich-Erkelenz D; Reif A; Reininghaus E; Rietschel M; Rouleau G; Rybakowski JK; Schalling M; Schofield P; Schubert KO; Schulze T; Schweizer B; Seemüller F; Severino G; Shekhtman T; Shilling P; Shimoda K; Simhandl C; Slaney C; Squassina A; Stamm T; Stopkova P; Tighe S; Tortorella A; Turecki G; Vieta E; Volkert J; Witt S; Wray N; Wright A; Young T; Zandi P; Zompo MD
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  • Corrigendum: TRANSLATIONAL PSYCHIATRY. 2022;12(1):278
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  • Review: FRONTIERS IN PSYCHIATRY. 2020;11:586083
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  • Thesis / dissertation: 2010
    Backlund, Lena
  • Letter: LAKARTIDNINGEN. 2009;106(23):1582
    Isacsson G; Backlund L; Spjut C; Andréewitch S
  • Meeting abstract: EUROPEAN PSYCHIATRY. 2008;23:S225
    Backlund L; Nikamo P; Rosvall L; Frisen L; Landen M; Ladanayi J; Traeskman-Bendz L; Agren H; Schalling M; Oesby U
  • Meeting abstract: EUROPEAN PSYCHIATRY. 2008;23:s227-s228
    Edman G; Backlund L; Adler M; Hallgren J; Sparen P; Osby U

Employments

  • Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2023-2026

Degrees and Education

  • Degree Of Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2010

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