Kuan-Yu Pan

About me
Publications
Grants
CV
Public outreach and news

Research

My research concerns occupational, psychiatric and geriatric epidemiology and public health.

I am currently leading two projects:
SPARK: Studies of occupational exposure to particles and cognitive health
This project investigates how exposure to particles and chemicals at the workplace affects workers' cognitive function and neuropathological changes in the brain.
Person-related work and mental and cardiovascular health
This project examines to what extent stressors from working with people (e.g., customers, patients, clients etc) increases workers' risk of cardiometabolic diseases and mental disorders.

I have taken part in two International collaborative projects:
EPHOR EPHOR — EPHOR Project
PSY-CA (PSYchosocial factors and CAncer incidence consortium)

Articles

Journal article: INTERNATIONAL JOURNAL OF CANCER. 2024;155(11):2109-2110
Reply to: Comments on "Psychosocial factors, health behaviors and risk of cancer incidence: Testing interaction and effect modification in an individual participant data meta-analysis"
Basten M; van Tuijl LA; Pan K-Y; Geerlings MI; Dekker J
Article: SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY. 2024;59(11):2031-2039
The role of job strain in the relationship between depression and long-term sickness absence: a register-based cohort study
Jarroch R; Falkstedt D; Nevriana A; Pan K-Y; Kauhanen J; Almroth M
Journal article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2024;:kwae325
Estimating Additive Interaction in Two-Stage Individual Participant Data Meta-Analysis.
Basten M; van Tuijl LA; Pan K-Y; Hoogendoorn AW; Lamers F; Ranchor AV; Dekker J; Frank P; Galenkamp H; Knol MJ; Noisel N; Payette Y; Sund ER; Zwinderman AH; Portengen L; Geerlings MI
Journal article: PSYCHOLOGICAL MEDICINE. 2024;54(10):2744-2757
The mediating role of health behaviors in the association between depression, anxiety and cancer incidence: an individual participant data meta-analysis
Pan K-Y; van Tuijl L; Basten M; Rijnhart JJM; de Graeff A; Dekker J; Geerlings MI; Hoogendoorn A; Ranchor AV; Vermeulen R; Portengen L; Voogd AC; Abell J; Awadalla P; Beekman ATF; Bjerkeset O; Boyd A; Cui Y; Frank P; Galenkamp H; Garssen B; Hellingman S; Hollander M; Huisman M; Huss A; Keats MR; Kok AAL; Krokstad S; van Leeuwen FE; Luik AI; Noisel N; Payette Y; Penninx BWJH; Picavet S; Rissanen I; Roest AM; Rosmalen JGM; Ruiter R; Schoevers RA; Soave D; Spaan M; Steptoe A; Stronks K; Sund ER; Sweeney E; Teyhan A; Twait EL; van der Willik KD; Lamers F
Article: JOURNAL OF AFFECTIVE DISORDERS. 2024;355:415-421
Diagnoses of common mental disorders among social workers in Sweden: A register-based cohort study
de Camargo CK; Falkstedt D; Pan K-Y; Almroth M; Nevriana A
Article: INTERNATIONAL JOURNAL OF CANCER. 2024;154(10):1745-1759
Psychosocial factors, health behaviors and risk of cancer incidence: Testing interaction and effect modification in an individual participant data meta-analysis
Basten M; Pan K-Y; van Tuijl LA; de Graeff A; Dekker J; Hoogendoorn AW; Lamers F; Ranchor AV; Vermeulen R; Portengen L; Voogd AC; Abell J; Awadalla P; Beekman ATF; Bjerkeset O; Boyd A; Cui Y; Frank P; Galenkamp H; Garssen B; Hellingman S; Huisman M; Huss A; Keats MR; Kok AAL; Krokstad S; van Leeuwen FE; Luik AI; Noisel N; Payette Y; Penninx BWJH; Rissanen I; Roest AM; Rosmalen JGM; Ruiter R; Schoevers RA; Soave D; Spaan M; Steptoe A; Stronks K; Sund ER; Sweeney E; Twait EL; Teyhan A; Verschuren WMM; van Der Willik KD; Geerlings MI
Article: SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH. 2024;50(4):300-309
The role of working conditions in educational differences in all-cause and ischemic heart disease mortality among Swedish men
Almroth M; Hemmingsson T; Falkstedt D; Kjellberg K; Carlsson E; Pan K-Y; Berglund K; Thern E
Article: PSYCHOLOGY HEALTH & MEDICINE. 2024;29(3):574-588
Association between psychosocial working conditions and well-being before retirement: a community-based study
Zhang Y; Yang W; Xu W; Pan K-Y
Article: AGEING & SOCIETY. 2024;:1-20
Labour market exit routes in high- and low-educated older workers before and after social insurance and retirement policy reforms in Sweden
Almroth M; Falkstedt D; Hemmingsson T; Albin M; Badarin K; Selander J; Gustavsson P; Bodin T; Thern E; Pan K-Y; Kjellberg K
Article: CANCER. 2023;129(20):3287-3299
Depression, anxiety, and the risk of cancer: An individual participant data meta-analysis
van Tuijl LA; Basten M; Pan K-Y; Vermeulen R; Portengen L; de Graeff A; Dekker J; Geerlings MI; Hoogendoorn A; Lamers F; Voogd AC; Abell J; Awadalla P; Beekman ATF; Bjerkeset O; Boyd A; Cui Y; Frank P; Galenkamp H; Garssen B; Hellingman S; Huisman M; Huss A; de Jong TR; Keats MR; Kok AAL; Krokstad S; van Leeuwen FE; Luik AI; Noisel N; Onland-Moret NC; Payette Y; Penninx BWJH; Rissanen I; Roest AM; Ruiter R; Schoevers RA; Soave D; Spaan M; Steptoe A; Stronks K; Sund ER; Sweeney E; Twait EL; Teyhan A; Verschuren WMM; van der Willik KD; Rosmalen JGM; Ranchor AV
Article: SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH. 2023;49(7):496-505
Trajectories of psychosocial working conditions and all-cause and cause-specific mortality: a Swedish register-based cohort study
Pan K-Y; Almroth M; Nevriana A; Hemmingsson T; Kjellberg K; Falkstedt D
Article: PSYCHOLOGICAL MEDICINE. 2023;53(9):3897-3907
Coping with COVID: risk and resilience factors for mental health in a German representative panel study
Riepenhausen A; Veer IM; Wackerhagen C; Reppmann ZC; Koeber G; Luis Ayuso-Mateos J; Bogemann SA; Corrao G; Felez-Nobrega M; Haro Abad JM; Hermans E; van Leeuwen J; Lieb K; Lorant V; Mary-Krause M; Mediavilla R; Melchior M; Mittendorfer-Rutz E; Compagnoni MM; Pan K-Y; Puhlmann L; Roelofs K; Sijbrandij M; Smith P; Tuescher O; Witteveen A; Zerban M; Kalisch R; Kroeger H; Walter H
Article: SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY. 2023;58(7):1109-1120
The impact of COVID-19 related adversity on the course of mental health during the pandemic and the role of protective factors: a longitudinal study among older adults in The Netherlands
Holwerda TJ; Jaarsma E; van Zutphen EM; Beekman ATF; Pan K-Y; van Vliet M; Stringa N; van den Besselaar JH; MacNeil-Vroomen JL; Hoogendijk EO; Kok AAL
Journal article: ALZHEIMERS & DEMENTIA. 2023;19(S8)
Dementia mediates the association of life‐course depression with mortality: A nationwide twin study
Yang W; Wang Z; Li X; Qi X; Zhang L; Pan K; Xu W
Journal article: ALZHEIMERS & DEMENTIA. 2023;19(S8)
Association of sleep duration with cognitive performance and structural brain differences: A large population‐based cross‐sectional study
Wang Z; Wang J; Yang W; Dove A; Qi X; Pan K; Xu W
Article: ALZHEIMERS & DEMENTIA. 2023;19(1):217-225
Association of life-course traumatic brain injury with dementia risk: A nationwide twin study
Zhang L; Yang W; Li X; Dove A; Qi X; Pan K-Y; Xu W
Journal article: ALZHEIMERS & DEMENTIA. 2022;18(S11)
Association of life‐course traumatic brain injury with the risk of dementia: a nationwide twin study
Zhang L; Yang W; Li X; Dove A; Qi X; Pan K; Xu W
Journal article: EUROPEAN JOURNAL OF CANCER. 2022;175:s6-s7
11 (PB-007) Poster Discussion Psychosocial factors and the incidence of breast cancer: two-stage individual participant data meta-analyses
Van Tuijl L; Basten M; Pan KY; de Graeff A; Dekker J; Hoogendoorn A; Lamers F; Geerlings M; Vermeulen R; Voogd A; Rosmalen J; Ranchor A; group P-C
Journal article: EUROPEAN JOURNAL OF CANCER. 2022;175:s95
283 (PB-107) Poster Depression, anxiety and the risk of breast cancer among premenopausal and postmenopausal women: an individual participant data meta-analysis
Basten M; van Tuijl LA; Pan KY; Spaan M; de Graeff A; Dekker J; Hoogendoorn AW; Lamers F; Ranchor AV; Vermeulen R; Voogd AC; Geerlings MI
Article: EUROPEAN PSYCHIATRY. 2022;65(1):e63
Association of depression with mortality in nationwide twins: The mediating role of dementia
Yang W; Wang Z; Li X; Qi X; Zhang L; Pan K-Y; Xu W
Article: BJPSYCH OPEN. 2022;8(5):e162
Predictors of mental health deterioration from pre- to post-COVID-19 outbreak
Ottenheim NR; Pan K-Y; Kok AAL; Jorg F; Eikelenboom M; Horsfall M; Luteijn RA; van Oppen P; Rhebergen D; Schoevers RA; Penninx BWJH; Giltay EJ
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2022;11(15):e025969
Association of Sleep Duration, Napping, and Sleep Patterns With Risk of Cardiovascular Diseases: A Nationwide Twin Study
Wang Z; Yang W; Li X; Qi X; Pan K-Y; Xu W
Article: JOURNAL OF AFFECTIVE DISORDERS. 2022;305:85-93
Mental health and perceived impact during the first Covid-19 pandemic year: A longitudinal study in Dutch case-control cohorts of persons with and without depressive, anxiety, and obsessive-compulsive disorders
Kok AAL; Pan K-Y; Rius-Ottenheim N; Jorg F; Eikelenboom M; Horsfall M; Luteijn R; van Oppen P; Rhebergen D; Schoevers RA; Giltay EJ; Penninx BWJH
Journal article: ALZHEIMERS & DEMENTIA. 2021;17(S10)
Association of life‐course depression with the risk of dementia in late life: A nationwide twin study
Yang W; Li X; Pan K; Yang R; Song R; Qi X; Pedersen NL; Xu W
Article: ALZHEIMERS & DEMENTIA. 2021;17(12):1914-1922
Association of cardiovascular risk burden with risk of dementia and brain pathologies: A population-based cohort study
Song R; Pan K-Y; Xu H; Qi X; Buchman AS; Bennett DA; Xu W
Article: BRAIN AND BEHAVIOR. 2021;11(10):e2340
Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses
van Tuijl LA; Voogd AC; de Graeff A; Hoogendoorn AW; Ranchor AV; Pan K-Y; Basten M; Lamers F; Geerlings MI; Abell JG; Awadalla P; Bakker MF; Beekman ATF; Bjerkeset O; Boyd A; Cui Y; Galenkamp H; Garssen B; Hellingman S; Huisman M; Huss A; Keats MR; Kok AAL; Luik AI; Noisel N; Onland-Moret NC; Payette Y; Penninx BWJH; Portengen L; Rissanen I; Roest AM; Rosmalen JGM; Ruiter R; Schoevers RA; Soave DM; Spaan M; Steptoe A; Stronks K; Sund ER; Sweeney E; Teyhan A; Vaartjes I; van der Willik KD; van Leeuwen FE; van Petersen R; Verschuren WMM; Visseren F; Vermeulen R; Dekker J
Article: AGE AND AGEING. 2021;50(5):1657-1665
Association of life satisfaction with disability-free survival: role of chronic diseases and healthy lifestyle
Wu W; Shang Y; Calderon-Larranaga A; Rizzuto D; Saadeh M; Dove A; Pan K-Y; Xu W
Article: ALZHEIMERS & DEMENTIA. 2021;17(8):1383-1390
Association of life-course depression with the risk of dementia in late life: A nationwide twin study
Yang W; Li X; Pan K-Y; Yang R; Song R; Qi X; Pedersen NL; Xu W
Article: AGE AND AGEING. 2021;50(2):480-487
Can health behaviours prolong survival and compress the period of survival with the disability? A population-based cohort study
Wu W; Xu W; Englund S; Shang Y; Pan K-Y; Rizzuto D
Article: LANCET PSYCHIATRY. 2021;8(2):121-129
The mental health impact of the COVID-19 pandemic on people with and without depressive, anxiety, or obsessive-compulsive disorders: a longitudinal study of three Dutch case-control cohorts
Pan K-Y; Kok AAL; Eikelenboom M; Horsfall M; Jorg F; Luteijn RA; Rhebergen D; van Oppen P; Giltay EJ; Penninx BWJH
Journal article: ALZHEIMERS & DEMENTIA. 2020;16(S10)
Association of cerebrovascular risk burden with mild cognitive impairment, dementia and brain vascular pathologies
Song R; Xu H; Pan K; Qi X; Buchman AS; Bennett DA; Xu W
Journal article: ALZHEIMERS & DEMENTIA. 2020;16(S10)
Association of cardiovascular risk burden with cognitive trajectories and structural brain differences
Song R; Xu H; Dintica CS; Pan K; Qi X; Buchman AS; Bennett DA; Xu W
Article: SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH. 2020;46(6):589-598
Psychosocial job strain and polypharmacy: a national cohort study
Tan ECK; Pan K-Y; Hanson LLM; Fastbom J; Westerlund H; Wang H-X
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2020;75(20):2525-2534
Associations Between Cardiovascular Risk, Structural Brain Changes, and Cognitive Decline
Song R; Xu H; Dintica CS; Pan K-Y; Qi X; Buchman AS; Bennett DA; Xu W
Article: AGING-US. 2020;12(4):3730-3746
The role of Apolipoprotein E epsilon4 in the association between psychosocial working conditions and dementia
Pan K-Y; Xu W; Mangialasche F; Grande G; Fratiglioni L; Wang H-X
Article: BMJ OPEN. 2019;9(11):e027659
The role of education in the association between self-rated health and levels of C-reactive protein: a cross-sectional study in rural areas of China
Tu R; Pan K-Y; Cai G; Yamamoto T; Wang H-X
Article: PLOS MEDICINE. 2019;16(9):e1002899
Psychosocial working conditions, trajectories of disability, and the mediating role of cognitive decline and chronic diseases: A population-based cohort study
Pan K-Y; Xu W; Mangialasche F; Wang R; Dekhtyar S; Calderon-Larranaga A; Fratiglioni L; Wang H-X
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2019;188(9):1627-1636
Association Between Speed of Multimorbidity Accumulation in Old Age and Life Experiences: A Cohort Study
Dekhtyar S; Vetrano DL; Marengoni A; Wang H-X; Pan K-Y; Fratiglioni L; Calderon-Larranaga A
Journal article: ALZHEIMERS & DEMENTIA. 2019;15(7S_Part_22):p1182
P3‐545: PASSIVE JOB AND DEMENTIA RISK IN OLDER ADULTS: THE ROLE OF APOLIPOPROTEIN E
Pan K-Y; Xu W; Mangialasche F; Grande G; Fratiglioni L; Wang H-X
Article: JOURNAL OF ALZHEIMERS DISEASE. 2019;67(1):315-325
Working Life Psychosocial Conditions in Relation to Late-Life Cognitive Decline: A Population-Based Cohort Study
Pan K-Y; Xu W; Mangialasche F; Dekhtyar S; Fratiglioni L; Wang H-X
Journal article: INNOVATION IN AGING. 2018;2(suppl_1):710-711
LONGITUDINAL TRAJECTORIES OF MULTIMORBIDITY IN OLD AGE: THE ROLE OF SOCIODEMOGRAPHIC FACTORS OVER THE LIFE COURSE
Dekhtyar S; Vetrano D; Marengoni A; Wang H; Pan K; Fratiglioni L; Calderon-Larrañaga A
Journal article: ALZHEIMERS & DEMENTIA. 2018;14(7S_Part_27):p1421
O4‐08‐01: LOW JOB DEMANDS IN MIDLIFE MAY ACCELERATE TOTAL BRAIN TISSUE LOSS IN LATER LIFE: THE ROLES OF EDUCATION AND LEISURE ACTIVITY
Pan K-Y; Xu W; Mangialsche F; Kalpouzos G; Bäckman L; Fratiglioni L; Wang H-X
Journal article: INNOVATION IN AGING. 2017;1(suppl_1):432-433
ASSOCIATION OF PSYCHOSOCIAL WORK STRESS WITH COGNITIVE DECLINE AND BRAIN STRUCTURE DIFFERENCES
Pan K; Xu W; Kalpouzos G; Bäckman L; Mangialasche F; Fratiglioni L; Wang H
Journal article: ALZHEIMERS & DEMENTIA. 2017;13(7S_Part_24):p1186
[P3–543]: ASSOCIATION OF PSYCHOSOCIAL WORK STRESS WITH COGNITIVE DECLINE AND BRAIN STRUCTURE DIFFERENCES
Pan K; Xu W; Mangialsche F; Kalpouzos G; Bäckman L; Fratiglioni L; Wang H
Article: JOURNAL OF INTERNAL MEDICINE. 2017;281(6):601-610
Work-related psychosocial stress and the risk of type 2 diabetes in later life
Pan K-Y; Xu W; Mangialasche F; Fratiglioni L; Wang H-X
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All other publications

Conference publication: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2023;33:ckad160.748
Suicide attempts among Swedish healthcare workers - a population-based cohort study
Nevriana A; Brulin E; Almroth M; Pan K-Y; Bodin T; Kjellberg K; Hemmingsson T; Falkstedt D
Conference publication: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2023;33:ckad160.135
Long-term sickness absence among adults with ADHD: the role of psychosocial working conditions
Ontiveros N; Nevriana A; Almroth M; Falkstedt D; Pan K-Y
Conference publication: 2023;:a13.1-a1a13
O-167 Trajectories of psychosocial working conditions and all-cause and cause-specific mortality: a Swedish register-based study
Pan K-Y; Almroth M; Nevriana A; Hemmingsson T; Kjellberg K; Falkstedt D
Letter: ACTA PSYCHIATRICA SCANDINAVICA. 2022;145(4):412-415
Attitudes towards COVID-19 vaccination: A comparison between persons with different chronicity of pre-pandemic depressive, anxiety or obsessive-compulsive disorders
Pan K-Y; Kok AAL; Penninx BWJH; Giltay EJ
Preprint: PSYARXIV. 2021
Coping with COVID: Risk and Resilience Factors for Mental Health in a German Representative Panel Study
Riepenhausen A; Veer I; Wackerhagen C; Reppmann ZC; Köber G; Mateos JLA; Bögemann S; Corrao G; Felez-Nobrega M; Haro JM; Hermans E; van Leeuwen J; Lieb K; Lorant V; Mary-Krause M; Mediavilla R; Melchior M; Mittendorfer-Rutz E; Compagnoni MM; Pan K-Y; Puhlmann L; Roelofs K; Sijbrandij M; Smith P; Tüscher O; Witteveen AB; Zerban M; Kalisch R; Kröger H; Walter H
Corrigendum: LANCET PSYCHIATRY. 2021;8(3):e11
Correction to Lancet Psychiatry 2021; 8: 121-29.
Doctoral thesis: 2019
Impact of psychosocial working conditions on health in older age
Pan, Kuan-Yu

Grants

SPARK: Studies of occupational exposure to particles and cognitive health
Swedish Research Council for Health Working Life and Welfare
1 January 2025 - 31 December 2027
Person-related work and mental and cardiovascular health consequences
AFA Försäkring
1 January 2023 - 31 December 2025

Employments

Assistant Professor, Institute of Environmental Medicine, Karolinska Institutet, 2024-2028

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2019

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