Kristina Becanovic

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Articles

Article: NPJ AGING AND MECHANISMS OF DISEASE. 2021;7(1):26

Age-related mitochondrial alterations in brain and skeletal muscle of the YAC128 model of Huntington disease

Becanovic K; Muhammad A; Gadawska I; Sachdeva S; Walker D; Lazarowski ER; Franciosi S; Park KHJ; Cote HCF; Leavitt BR
Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2020;374(1):126-133

Effects of a Novel Psychomotor Stabilizer, IRL790, on Biochemical Measures of Synaptic Markers and Neurotransmission

Becanovic K; de Donno MV; Sousa VC; Tedroff J; Svenningsson P
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2019;104(6):1116-1126

Length of Uninterrupted CAG, Independent of Polyglutamine Size, Results in Increased Somatic Instability, Hastening Onset of Huntington Disease

Wright GEB; Collins JA; Kay C; McDonald C; Dolzhenko E; Xia Q; Becanovic K; Drogemoller BI; Semaka A; Nguyen CM; Trost B; Richards F; Bijlsma EK; Squitieri F; Ross CJD; Scherer SW; Eberle MA; Yuen RKC; Hayden MR
Article: PARKINSONISM & RELATED DISORDERS. 2019;61:101-105

Clinical and genetic characteristics of late-onset Huntington's disease.

Oosterloo M; Bijlsma EK; van Kuijk SM; Minkels F; de Die-Smulders CE
Article: JOURNAL OF HUNTINGTON'S DISEASE. 2018;7(3):223-237

Computational Analysis of Transcriptional Regulation Sites at the HTT Gene Locus

De Souza RAG; Kosior N; Thomson SB; Mathelier A; Zhang AW; Becanovic K; Wasserman WW; Leavitt BR
Article: NATURE NEUROSCIENCE. 2015;18(6):807-816

A SNP in the HTT promoter alters NF-κB binding and is a bidirectional genetic modifier of Huntington disease

Becanovic K; Norremolle A; Neal SJ; Kay C; Collins JA; Arenillas D; Lilja T; Gaudenzi G; Manoharan S; Doty CN; Beck J; Lahiri N; Portales-Casamar E; Warby SC; Connolly C; DeSouza RAG; Tabrizi SJ; Hermanson O; Langbehn DR; Hayden MR; Wasserman WW; Leavitt BR
Article: HUMAN MOLECULAR GENETICS. 2014;23(3):717-729

p53 increases caspase-6 expression and activation in muscle tissue expressing mutant huntingtin.

Ehrnhoefer DE; Skotte NH; Ladha S; Nguyen YTN; Qiu X; Deng Y; Huynh KT; Engemann S; Nielsen SM; Becanovic K; Leavitt BR; Hasholt L; Hayden MR
Article: HUMAN MOLECULAR GENETICS. 2012;21(14):3097-3111

Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease.

Tang B; Becanovic K; Desplats PA; Spencer B; Hill AM; Connolly C; Masliah E; Leavitt BR; Thomas EA
Article: JOURNAL OF IMMUNOLOGY. 2010;185(11):6883-6890

IL-22RA2 Associates with Multiple Sclerosis and Macrophage Effector Mechanisms in Experimental Neuroinflammation

Beyeen AD; Adzemovic MZ; Ockinger J; Stridh P; Becanovic K; Laaksonen H; Lassmann H; Harris RA; Hillert J; Alfredsson L; Celius EG; Harbo HF; Kockum I; Jagodic M; Olsson T
Article: PLOS ONE. 2010;5(9):e12716

Fine-Mapping Resolves Eae23 into Two QTLs and Implicates ZEB1 as a Candidate Gene Regulating Experimental Neuroinflammation in Rat

Stridh P; Hedreul MT; Beyeen AD; Adzemovic MZ; Laaksonen H; Gillett A; Ockinger J; Marta M; Lassmann H; Becanovic K; Jagodic M; Olsson T
Article: HUMAN MOLECULAR GENETICS. 2010;19(8):1438-1452

Transcriptional changes in Huntington disease identified using genome-wide expression profiling and cross-platform analysis.

Becanovic K; Pouladi MA; Lim RS; Kuhn A; Pavlidis P; Luthi-Carter R; Hayden MR; Leavitt BR
Article: HUMAN MOLECULAR GENETICS. 2010;19(4):609-622

Expression analysis of novel striatal-enriched genes in Huntington disease.

Mazarei G; Neal SJ; Becanovic K; Luthi-Carter R; Simpson EM; Leavitt BR
Article: GENES AND IMMUNITY. 2010;11(1):21-36

Multiple loci comprising immune-related genes regulate experimental neuroinflammation

Marta M; Stridh P; Becanovic K; Gillett A; Ockinger J; Lorentzen JC; Jagodic M; Olsson T
Article: ANNALS OF THE RHEUMATIC DISEASES. 2009;68(12):1925-1932

Definition of arthritis candidate risk genes by combining rat linkage-mapping results with human case-control association data

Backdahl L; Guo JP; Jagodic M; Becanovic K; Ding B; Olsson T; Lorentzen JC
Article: HUMAN MOLECULAR GENETICS. 2007;16(15):1845-1861

Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage.

Kuhn A; Goldstein DR; Hodges A; Strand AD; Sengstag T; Kooperberg C; Becanovic K; Pouladi MA; Sathasivam K; Cha J-HJ; Hannan AJ; Hayden MR; Leavitt BR; Dunnett SB; Ferrante RJ; Albin R; Shelbourne P; Delorenzi M; Augood SJ; Faull RLM; Olson JM; Bates GP; Jones L; Luthi-Carter R
Article: JOURNAL OF IMMUNOLOGY. 2006;176(10):6055-6064

Advanced intercross line mapping of Eae5 reveals Ncf-1 and CLDN4 as candidate genes for experimental autoimmune encephalomyelitis

Becanovic K; Jagodic M; Sheng JR; Dahlman I; Aboul-Enein F; Wallstrom E; Olofsson P; Holmdahl R; Lassmann H; Olsson T
Article: GENETICS. 2005;170(1):283-289

Eae19, a new locus on rat chromosome 15 regulating experimental autoimmune encephalomyelitis

Sheng JR; Jagodic M; Dahlman I; Becanovic K; Nohra R; Marta M; Iacobaeus E; Olsson T; Wallström E
Article: JOURNAL OF IMMUNOLOGY. 2005;174(2):918-924

Resolution of a 16.8-mb autoimmunity-regulating rat chromosome 4 region into multiple encephalomyrelitis quantitative trait loci and evidence for epistasis

Jagodic M; Marta M; Becanovic K; Sheng JR; Nohra R; Olsson T; Lorentzen JC
Article: JOURNAL OF IMMUNOLOGY. 2004;173(2):1366-1373

An advanced intercross line resolves Eae18 into two narrow quantitative trait loci syntenic to multiple sclerosis candidate loci

Jagodic M; Becanovic K; Sheng JR; Wu XC; Bäckdahl L; Lorentzen JC; Wallström E; Olsson T
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2003;33(7):1907-1916

Paradoxical effects of arthritis-regulating chromosome 4 regions on myelin oligodendrocyte glycoprotein-induced encephalomyelitis in congenic rats

Becanovic K; Bäckdahl L; Wallström E; Aboul-Enein F; Lassmann H; Olsson T; Lorentzen JC
Article: JOURNAL OF IMMUNOLOGY. 2003;170(2):1062-1069

New loci regulating rat myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis

Becanovic K; Wallstrom E; Kornek B; Glaser A; Broman KW; Dahlman I; Ofsson P; Holmdahl R; Luthman H; Lassmann H; Olsson T
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2002;56(3):248-253

Identification of rat quantitative trait loci that regulate LPS-Induced pro-inflammatory cytokine responses

Xu HW; Wallström E; Becanovic K; Dahlman I; Lorentzen JC
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Corrigendum: NPJ AGING AND MECHANISMS OF DISEASE. 2021;7(1):27

Age-related mitochondrial alterations in brain and skeletal muscle of the YAC128 model of Huntington disease (vol 7, 26, 2021)

Becanovic K; Asghar M; Gadawska I; Sachdeva S; Walker D; Lazarowski ER; Franciosi S; Park KHJ; Cote HCF; Leavitt BR
Editorial comment: CLINICAL GENETICS. 2006;70(5):383-385

Age-related dysfunction of the cellular powerplants

Becanovic K; Leavitt BR
Review: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2004;60(1-2):39-51

Current gene-mapping strategies in experimental models of multiple sclerosis

Becanovic K; Jagodic M; Wallström E; Olsson T
Thesis / dissertation: 2003

Genetic regulation of autoimmune neuroinflammation

Becanovic, Kristina

Employments

Affiliated to Research, Department of Clinical Neuroscience, Karolinska Institutet, 2023-2024

Degrees and Education

Doctor Of Philosophy, Department of Medicine, Solna, Karolinska Institutet, 2003

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