Keith Humphreys

About me
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Grants
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Public outreach and news

About me

I obtained my doctoral degree in Statistics at Southampton University (U.K.) in 1996. In 2005, I was appointed Senior Lecturer in Biostatistics at Karolinska Institutet at the Department of Medical Epidemiology and Biostatistics. In 2019, I was appointed as Professor in Biostatistics in the same department.

Education:
1996, PhD (Social Statistics), Southampton University, U.K.
1997, Postdoc (Statistics/Psychometrics), Stockholm University
1999, Postdoc (Statistics), Glasgow University, U.K.
2002, Docent (Biostatistics), Karolinska Institutet

Research

I am involved in a number of research projects which have a general aim to contribute to the understanding of breast cancer tumour progression and to the identification of women with high risk for breast cancer, in particular that which is aggressive/has poor prognosis. We develop novel statistical approaches and apply them to large, and detailed, studies of breast cancer/mammography screening. My research builds on previous work on the identification of genetic variants for breast cancer, the development of statistical models of breast cancer risk and tumour growth and the development of novel approaches for measuring mammographic density.

Current supervision of PhD students and Postdoctoral researcher

Letizia Orsini (PhD student)
Evripidis Kapanidis (PhD student)
Alessandro Gasparini (Postdoc)

Teaching

I am course director for the Biostatistics course on the master program for Molecular Techniques in the Life Sciences.

Selected publications

Article: JOURNAL OF COMPUTATIONAL AND GRAPHICAL STATISTICS (JCGS). 2023;32(4):1393-1401
Quasi-Monte Carlo Methods for Binary Event Models with Complex Family Data
Christoffersen B; Mahjani B; Clements M; Kjellstrom H; Humphreys K
Article: CANCERS. 2023;15(3):912
Tumour Growth Models of Breast Cancer for Evaluating Early Detection-A Summary and a Simulation Study
Strandberg R; Abrahamsson L; Isheden G; Humphreys K
Article: STATISTICAL METHODS IN MEDICAL RESEARCH. 2022;31(12):2415-2430
A natural history and copula-based joint model for regional and distant breast cancer metastasis
Gasparini A; Humphreys K
Article: MATHEMATICAL BIOSCIENCES. 2022;353:108897
A unifying framework for continuous tumour growth modelling of breast cancer screening data
Isheden G; Humphreys K
Article: STATISTICAL METHODS IN MEDICAL RESEARCH. 2022;31(5):862-881
Estimating latent, dynamic processes of breast cancer tumour growth and distant metastatic spread from mammography screening data
Gasparini A; Humphreys K
Article: BIOMETRICS. 2022;78(1):376-387
Random effects models of lymph node metastases in breast cancer: quantifying the roles of covariates and screening using a continuous growth model
Isheden G; Czene K; Humphreys K
Article: INTERNATIONAL JOURNAL OF CANCER. 2021;149(6):1348-1357
Lymph node metastases in breast cancer: Investigating associations with tumor characteristics, molecular subtypes and polygenic risk score using a continuous growth model
Isheden G; Grassmann F; Czene K; Humphreys K
Article: STATISTICAL METHODS IN MEDICAL RESEARCH. 2020;29(2):374-395
Continuous tumour growth models, lead time estimation and length bias in breast cancer screening studies
Abrahamsson L; Isheden G; Czene K; Humphreys K
Article: MATHEMATICAL BIOSCIENCES. 2019;318:108270
Statistical models of tumour onset and growth for modern breast cancer screening cohorts
Strandberg JR; Humphreys K
Article: STATISTICAL METHODS IN MEDICAL RESEARCH. 2019;28(12):3822-3842
Joint models of tumour size and lymph node spread for incident breast cancer cases in the presence of screening
Isheden G; Abrahamsson L; Andersson T; Czene K; Humphreys K
Review: MEDICAL PHYSICS. 2019;46(4):1938-1946
Detection of potential microcalcification clusters using multivendor for-presentation digital mammograms for short-term breast cancer risk estimation
Ali MA; Eriksson M; Czene K; Hall P; Humphreys K
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2017;186(9):1065-1073
Mammographic Density Reduction as a Prognostic Marker for Postmenopausal Breast Cancer: Results Using a Joint Longitudinal-Survival Modeling Approach
Andersson TM-L; Crowther MJ; Czene K; Hall P; Humphreys K
Article: CANCER EPIDEMIOLOGY. 2017;46:50-56
Assessment of lead-time bias in estimates of relative survival for breast cancer
Andersson TM-L; Rutherford MJ; Humphreys K
Article: STATISTICAL METHODS IN MEDICAL RESEARCH. 2016;25(4):1620-1637
A statistical model of breast cancer tumour growth with estimation of screening sensitivity as a function of mammographic density
Abrahamsson L; Humphreys K
Article: BREAST CANCER RESEARCH. 2015;17:116
Breast cancer tumour growth modelling for studying the association of body size with tumour growth rate and symptomatic detection using case-control data
Abrahamsson L; Czene K; Hall P; Humphreys K
Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2014;23(7):1314-1323
Enhancement of Mammographic Density Measures in Breast Cancer Risk Prediction
Cheddad A; Czene K; Shepherd JA; Li J; Hall P; Humphreys K
Article: BREAST CANCER RESEARCH. 2012;14(1):R25
Breast cancer risk prediction and individualised screening based on common genetic variation and breast density measurement
Darabi H; Czene K; Zhao W; Liu J; Hall P; Humphreys K
Article: PLOS ONE. 2011;6(8):e22547
The Genetic Structure of the Swedish Population
Humphreys K; Grankvist A; Leu M; Hall P; Liu J; Ripatti S; Rehnstroem K; Groop L; Klareskog L; Ding B; Gronberg H; Xu J; Pedersen NL; Lichtenstein P; Mattingsdal M; Andreassen OA; O'Dushlaine C; Purcell SM; Sklar P; Sullivan PF; Hultman CM; Palmgren J; Magnusson PKE
Article: INTERNATIONAL JOURNAL OF BIOSTATISTICS. 2010;6(1):Article-20
A Principal Stratification Approach to Assess the Differences in Prognosis between Cancers Caused by Hormone Replacement Therapy and by Other Factors
Sjolander A; Vansteelandt S; Humphreys K
Article: STATISTICAL APPLICATIONS IN GENETICS AND MOLECULAR BIOLOGY. 2009;8(1):Article-35
Ancestral Recombination Graphs under Non-Random Ascertainment, with Applications to Gene Mapping
Hossjer O; Hartman L; Humphreys K
Article: GENETIC EPIDEMIOLOGY. 2007;31(6):528-540
Testing association in the presence of linkage - A powerful score for binary traits
Jonasdottir G; Humphreys K; Palmgren J
Article: PSYCHOMETRIKA. 2003;68(3):391-412
Variational approximations for categorical causal modeling with latent variables
Humphreys K; Titterington DM
Article: JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY. 2002;64:549-564
On the adequacy of variational lower bound functions for likelihood-based inference in Markovian models with missing values
Hall P; Humphreys K; Titterington DM
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Articles

Article: STATISTICS IN MEDICINE. 2024;43(15):2957-2971
Random effects models of tumour growth for investigating interval breast cancer
Orsini L; Czene K; Humphreys K
Article: ESMO OPEN. 2024;9(4):102972
Worse histopathology and prognosis in women with breast cancer diagnosed during the second trimester of pregnancy
Gkekos L; Lundberg FE; Humphreys K; Fredriksson I; Johansson ALV
Article: JAMA ONCOLOGY. 2024;10(1):63-70
Breast Cancer Incidence After a False-Positive Mammography Result
Mao X; He W; Humphreys K; Eriksson M; Holowko N; Yang H; Tapia J; Hall P; Czene K
Article: JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2023;115(11):1310-1317
Prediction of breast cancer risk for sisters of women attending screening
Mao X; He W; Eriksson M; Lindstroem LS; Holowko N; Bajalica-Lagercrantz S; Hammarstrom M; Grassmann F; Humphreys K; Easton D; Hall P; Czene K
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2023;75:s239-s240
FAMILIAL RISK OF POSTPARTUM PSYCHOSIS
Kepinska A; Robakis T; Humphreys K; Kahn R; Munk-Olsen T; Bergink V; Mahjani B
Article: STATISTICS IN MEDICINE. 2023;42(21):3816-3837
Novel predictions of invasive breast cancer risk in mammography screening cohorts
Strandberg R; Czene K; Hall P; Humphreys K
Article: EUROPEAN JOURNAL OF CANCER. 2023;191:112953
Transcriptional intra-tumour heterogeneity predicted by deep learning in routine breast histopathology slides provides independent prognostic information
Wang Y; Ali MA; Vallon-Christersson J; Humphreys K; Hartman J; Rantalainen M
Article: SCIENTIFIC REPORTS. 2023;13(1):14194
Influence of mammographic density and compressed breast thickness on true mammographic sensitivity: a cohort study
Strandberg R; Illipse M; Czene K; Hall P; Humphreys K
Article: CANCERS. 2023;15(13):3313
Spectrum and Frequency of Germline FANCM Protein-Truncating Variants in 44,803 European Female Breast Cancer Cases
Figlioli G; Billaud A; Wang Q; Bolla MK; Dennis J; Lush M; Kvist A; Adank MA; Ahearn TU; Antonenkova NN; Auvinen P; Behrens S; Bermisheva M; Bogdanova NV; Bojesen SE; Bonanni B; Bruening T; Camp NJ; Campbell A; Castelao JE; Cessna MH; Czene K; Devilee P; Doerk T; Eriksson M; Fasching PA; Flyger H; Gabrielson M; Gago-Dominguez M; Garcia-Closas M; Glendon G; Garcia EG; Gonzalez-Neira A; Grassmann F; Guenel P; Hahnen E; Hamann U; Hillemanns P; Hooning MJ; Hoppe R; Howell A; Humphreys K; Jakubowska A; Khusnutdinova EK; Kristensen VN; Lindblom A; Loizidou MA; Lubinski J; Mannermaa A; Maurer T; Mavroudis D; Newman WG; Obi N; Panayiotidis MI; Radice P; Rashid MU; Rhenius V; Ruebner M; Saloustros E; Sawyer EJ; Schmidt MK; Schmutzler RK; Shah MT; Southey MC; Tomlinson I; Truong T; van Veen EM; Wendt C; Yang XR; Michailidou K; Dunning AM; Pharoah PDP; Easton DF; Andrulis IL; Evans DG; Hollestelle A; Chang-Claude J; Milne RL; Peterlongo P
Article: BREAST CANCER RESEARCH. 2023;25(1):64
Studying the association between longitudinal mammographic density measurements and breast cancer risk: a joint modelling approach
Illipse M; Czene K; Hall P; Humphreys K
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2023;31(5):578-587
FANCM missense variants and breast cancer risk: a case-control association study of 75,156 European women
Figlioli G; Billaud A; Ahearn TU; Antonenkova NN; Becher H; Beckmann MW; Behrens S; Benitez J; Bermisheva M; Blok MJ; Bogdanova NV; Bonanni B; Burwinkel B; Camp NJ; Campbell A; Castelao JE; Cessna MH; Chanock SJ; Czene K; Devilee P; Doerk T; Engel C; Eriksson M; Fasching PA; Figueroa JD; Gabrielson M; Gago-Dominguez M; Garcia-Closas M; Gonzalez-Neira A; Grassmann F; Guenel P; Guendert M; Hadjisavvas A; Hahnen E; Hall P; Hamann U; Harrington PA; He W; Hillemanns P; Hollestelle A; Hooning MJ; Hoppe R; Howell A; Humphreys K; Jager A; Jakubowska A; Khusnutdinova EK; Ko Y-D; Kristensen VN; Lindblom A; Lissowska J; Lubinski J; Mannermaa A; Manoukian S; Margolin S; Mavroudis D; Newman WG; Obi N; Panayiotidis MI; Rashid MU; Rhenius V; Rookus MA; Saloustros E; Sawyer EJ; Schmutzler RK; Shah M; Sironen R; Southey MC; Suvanto M; Tollenaar RAEM; Tomlinson I; Truong T; van der Kolk LE; van Veen EM; Wappenschmidt B; Yang XR; Bolla MK; Dennis J; Dunning AM; Easton DF; Lush M; Michailidou K; Pharoah PDP; Wang Q; Adank MA; Schmidt MK; Andrulis IL; Chang-Claude J; Nevanlinna H; Chenevix-Trench G; Evans DG; Milne RL; Radice P; Peterlongo P
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2023;110(3):475-486
The impact of coding germline variants on contralateral breast cancer risk and survival
Morra A; Mavaddat N; Muranen TA; Ahearn TU; Allen J; Andrulis IL; Auvinen P; Becher H; Behrens S; Blomqvist C; Bojesen SE; Bolla MK; Brauch H; Camp NJ; Carvalho S; Castelao JE; Cessna MH; Chang-Claude J; Chenevix-Trench G; Czene K; Decker B; Dennis J; Doerk T; Dorling L; Dunning AM; Ekici AB; Eriksson M; Evans DG; Fasching PA; Figueroa JD; Flyger H; Gago-Dominguez M; Garcia-Closas M; Geurts-Giele WRR; Giles GG; Guenel P; Gundert M; Hahnen E; Hall P; Hamann U; Harrington PA; He W; Heikkila P; Hooning MJ; Hoppe R; Howell A; Humphreys K; Jakubowska A; Jung AY; Keeman R; Kristensen VN; Lubinski J; Mannermaa A; Manoochehri M; Manoukian S; Margolin S; Mavroudis D; Milne RL; Mulligan AM; Newman WG; Park-Simon T-W; Peterlongo P; Pharoah PDP; Rhenius V; Saloustros E; Sawyer EJ; Schmutzler RK; Shah M; Spurdle AB; Tomlinson I; Truong T; van Veen EM; Vreeswijk MPG; Wang Q; Wendt C; Yang XR; Nevanlinna H; Devilee P; Easton DF; Schmidt MK
Journal article: CANCER RESEARCH. 2023;83(5_Supplement):p4-03-09-p4-03-09
Abstract P4-03-09: Risk of breast cancer after false-positive mammography recalls: a matched cohort study
Mao X; He W; Humphreys K; Yang H; Czene K
Article: JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK : JNCCN. 2023;21(2):143-152.e4
Factors Associated With False-Positive Recalls in Mammography Screening
Mao X; He W; Humphreys K; Eriksson M; Holowko N; Strand F; Hall P; Czene K
Journal article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2023;31(5):578-587
FANCM missense variants and breast cancer risk: a case-control association study of 75,156 European women
Figlioli G; Billaud A; Ahearn TU; Antonenkova NN; Becher H; Beckmann MW; Behrens S; Benitez J; Bermisheva M; Blok MJ; Bogdanova NV; Bonanni B; Burwinkel B; Camp NJ; Campbell A; Castelao JE; Cessna MH; Chanock SJ; Czene K; Devilee P; Doerk T; Engel C; Eriksson M; Fasching PA; Figueroa JD; Gabrielson M; Gago-Dominguez M; Garcia-Closas M; Gonzalez-Neira A; Grassmann F; Guenel P; Guendert M; Hadjisavvas A; Hahnen E; Hall P; Hamann U; Harrington PA; He W; Hillemanns P; Hollestelle A; Hooning MJ; Hoppe R; Howell A; Humphreys K; Jager A; Jakubowska A; Khusnutdinova EK; Ko Y-D; Kristensen VN; Lindblom A; Lissowska J; Lubinski J; Mannermaa A; Manoukian S; Margolin S; Mavroudis D; Newman WG; Obi N; Panayiotidis MI; Rashid MU; Rhenius V; Rookus MA; Saloustros E; Sawyer EJ; Schmutzler RK; Shah M; Sironen R; Southey MC; Suvanto M; Tollenaar RAEM; Tomlinson I; Truong T; van der Kolk LE; van Veen EM; Wappenschmidt B; Yang XR; Bolla MK; Dennis J; Dunning AM; Easton DF; Lush M; Michailidou K; Pharoah PDP; Wang Q; Adank MA; Schmidt MK; Andrulis IL; Chang-Claude J; Nevanlinna H; Chenevix-Trench G; Evans DG; Milne RL; Radice P; Peterlongo P
Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2022;31(3):569-577
Estimating Distributions of Breast Cancer Onset and Growth in a Swedish Mammography Screening Cohort
Strandberg R; Czene K; Eriksson M; Hall P; Humphreys K
Article: BREAST CANCER RESEARCH. 2022;24(1):15
Assessing lead time bias due to mammography screening on estimates of loss in life expectancy
Syriopoulou E; Gasparini A; Humphreys K; Andersson TM-L
Article: EUROPEAN JOURNAL OF CANCER. 2022;162:194-205
Interval breast cancer is associated with interferon immune response
Ugalde-Morales E; Grassmann F; Humphreys K; Li J; Eriksson M; Tobin NP; Lindstrom LS; Vallon-Christersson J; Borg A; Hall P; Czene K
Article: INTERNATIONAL JOURNAL OF CANCER. 2021;148(6):1351-1359
Mammography features for early markers of aggressive breast cancer subtypes and tumor characteristics: A population-based cohort study
Tan PS; Ali MA; Eriksson M; Hall P; Humphreys K; Czene K
Article: INTERNATIONAL JOURNAL OF CANCER. 2021;148(4):884-894
Association between breast cancer risk and disease aggressiveness: Characterizing underlying gene expression patterns
Ugalde-Morales E; Grassmann F; Humphreys K; Li J; Eriksson M; Tobin NP; Borg A; Vallon-Christersson J; Hall P; Czene K
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2021;384(5):428-439
Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women
Dorling L; Carvalho S; Allen J; Gonzalez-Neira A; Luccarini C; Wahlstrom C; Pooley KA; Parsons MT; Fortuno C; Wang Q; Bolla MK; Dennis J; Keeman R; Alonso MR; Alvarez N; Herraez B; Fernandez V; Nunez-Torres R; Osorio A; Valcich J; Li M; Torngren T; Harrington PA; Baynes C; Conroy DM; Decker B; Fachal L; Mavaddat N; Ahearn T; Aittomaki K; Antonenkova NN; Arnold N; Arveux P; Ausems MGEM; Auvinen P; Becher H; Beckmann MW; Behrens S; Bermisheva M; Bialkowska K; Blomqvist C; Bogdanova NV; Bogdanova-Markov N; Bojesen SE; Bonanni B; Borresen-Dale A-L; Brauch H; Bremer M; Briceno I; Bruning T; Burwinkel B; Cameron DA; Camp NJ; Campbell A; Carracedo A; Castelao JE; Cessna MH; Chanock SJ; Christiansen H; Collee JM; Cordina-Duverger E; Cornelissen S; Czene K; Doerk T; Ekici AB; Engel C; Eriksson M; Fasching PA; Figueroa J; Flyger H; Foersti A; Gabrielson M; Gago-Dominguez M; Georgoulias V; Gil F; Giles GG; Glendon G; Garcia EBG; Alnaes GIG; Guenel P; Hadjisavvas A; Haeberle L; Hahnen E; Hall P; Hamann U; Harkness EF; Hartikainen JM; Hartman M; He W; Heemskerk-Gerritsen BAM; Hillemanns P; Hogervorst FBL; Hollestelle A; Ho WK; Hooning MJ; Howell A; Humphreys K; Idris F; Jakubowska A; Jung A; Kapoor PM; Kerin MJ; Khusnutdinova E; Kim S-W; Ko Y-D; Kosma V-M; Kristensen VN; Kyriacou K; Lakeman IMM; Lee JW; Lee MH; Li J; Lindblom A; Lo W-Y; Loizidou MA; Lophatananon A; Lubinski J; MacInnis RJ; Madsen MJ; Mannermaa A; Manoochehri M; Manoukian S; Margolin S; Martinez ME; Maurer T; Mavroudis D; McLean C; Meindl A; Mensenkamp AR; Michailidou K; Miller N; Taib NAM; Muir K; Mulligan AM; Nevanlinna H; Newman WG; Nordestgaard BG; Ng P-S; Oosterwijk JC; Park SK; Park-Simon T-W; Perez JIA; Peterlongo P; Porteous DJ; Prajzendanc K; Prokofyeva D; Radice P; Rashid MU; Rhenius V; Rookus MA; Rudiger T; Saloustros E; Sawyer EJ; Schmutzler RK; Schneeweiss A; Schurmann P; Shah M; Sohn C; Southey MC; Surowy H; Suvanto M; Thanasitthichai S; Tomlinson I; Torres D; Truong T; Tzardi M; Valova Y; van Asperen CJ; Van Dam RM; van den Ouweland AMW; van der Kolk LE; van Veen EM; Wendt C; Williams JA; Yang XR; Yoon S-Y; Zamora MP; Evans DG; de la Hoya M; Simard J; Antoniou AC; Borg A; Andrulis IL; Chang-Claude J; Garcia-Closas M; Chenevix-Trench G; Milne RL; Pharoah PDP; Schmidt MK; Spurdle AB; Vreeswijk MPG; Benitez J; Dunning AM; Kvist A; Teo SH; Devilee P; Easton DF
Article: GENETIC EPIDEMIOLOGY. 2020;44(5):442-468
Transcriptome-wide association study of breast cancer risk by estrogen-receptor status
Feng H; Gusev A; Pasaniuc B; Wu L; Long J; Abu-full Z; Aittomaki K; Andrulis IL; Anton-Culver H; Antoniou AC; Arason A; Arndt V; Aronson KJ; Arun BK; Asseryanis E; Auer PL; Azzollini J; Balmana J; Barkardottir RB; Barnes DR; Barrowdale D; Beckmann MW; Behrens S; Benitez J; Bermisheva M; Bialkowska K; Blanco A; Blomqvist C; Boeckx B; Bogdanova NV; Bojesen SE; Bolla MK; Bonanni B; Borg A; Brauch H; Brenner H; Briceno I; Broeks A; Bruening T; Burwinkel B; Cai Q; Caldes T; Caligo MA; Campbell I; Canisius S; Campa D; Carter BD; Carter J; Castelao JE; Chang-Claude J; Chanock SJ; Christiansen H; Chung WK; Claes KBM; Clarke CL; Couch FJ; Cox A; Cross SS; Cybulski C; Czene K; Daly MB; de la Hoya M; De Leeneer K; Dennis J; Devilee P; Diez O; Domchek SM; Doerk T; dos-Santos-Silva I; Dunning AM; Dwek M; Eccles DM; Ejlertsen B; Ellberg C; Engel C; Eriksson M; Fasching PA; Fletcher O; Flyger H; Fostira F; Friedman E; Fritschi L; Frost D; Gabrielson M; Ganz PA; Gapstur SM; Garber J; Garcia-Closas M; Garcia-Saenz JA; Gaudet MM; Giles GG; Glendon G; Godwin AK; Goldberg MS; Goldgar DE; Gonzalez-Neira A; Greene MH; Gronwald J; Guenel P; Haiman CA; Hall P; Hamann U; Hake C; He W; Heyworth J; Hogervorst FBL; Hollestelle A; Hooning MJ; Hoover RN; Hopper JL; Huang G; Hulick PJ; Humphreys K; Imyanitov EN; Isaacs C; Jakimovska M; Jakubowska A; James P; Janavicius R; Jankowitz RC; John EM; Johnson N; Joseph V; Jung A; Karlan BY; Khusnutdinova E; Kiiski J; Konstantopoulou I; Kristensen VN; Laitman Y; Lambrechts D; Lazaro C; Leroux D; Leslie G; Lester J; Lesueur F; Lindor N; Lindstrom S; Lo W-Y; Loud JT; Lubinski J; Makalic E; Mannermaa A; Manoochehri M; Manoukian S; Margolin S; Martens JWM; Martinez ME; Matricardi L; Maurer T; Mavroudis D; McGuffog L; Meindl A; Menon U; Michailidou K; Kapoor PM; Miller A; Montagna M; Moreno F; Moserle L; Mulligan AM; Muranen TA; Nathanson KL; Neuhausen SL; Nevanlinna H; Nevelsteen I; Nielsen FC; Nikitina-Zake L; Offit K; Olah E; Olopade OI; Olsson H; Osorio A; Papp J; Park-Simon T-W; Parsons MT; Pedersen IS; Peixoto A; Peterlongo P; Peto J; Pharoah PDP; Phillips K-A; Plaseska-Karanfilska D; Poppe B; Pradhan N; Prajzendanc K; Presneau N; Punie K; Pylkas K; Radice P; Rantala J; Rashid MU; Rennert G; Risch HA; Robson M; Romero A; Saloustros E; Sandler DP; Santos C; Sawyer EJ; Schmidt MK; Schmidt DF; Schmutzler RK; Schoemaker MJ; Scott RJ; Sharma P; Shu X-O; Simard J; Singer CF; Skytte A-B; Soucy P; Southey MC; Spinelli JJ; Spurdle AB; Stone J; Swerdlow AJ; Tapper WJ; Taylor JA; Teixeira MR; Terry MB; Teule A; Thomassen M; Thoene K; Thull DL; Tischkowitz M; Toland AE; Tollenaar RAEM; Torres D; Truong T; Tung N; Vachon CM; van Asperen CJ; van den Ouweland AMW; van Rensburg EJ; Vega A; Viel A; Vieiro-Balo P; Wang Q; Wappenschmidt B; Weinberg CR; Weitzel J; Wendt C; Winqvist R; Yang XR; Yannoukakos D; Ziogas A; Milne RL; Easton DF; Chenevix-Trench G; Zheng W; Kraft P; Jiang X
Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2020;49(1):216-232
Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk, in the Breast Cancer Association Consortium
Kapoor PM; Lindstrom S; Behrens S; Wang X; Michailidou K; Bolla MK; Wang Q; Dennis J; Dunning AM; Pharoah PDP; Schmidt MK; Kraft P; Garcia-Closas M; Easton DF; Milne RL; Chang-Claude J
Journal article: EPIDEMIOLOGIC METHODS. 2020;9(1):20190022
Random effects tumour growth models for identifying image markers of mammography screening sensitivity
Abrahamsson L; Ali MA; Czene K; Isheden G; Hall P; Humphreys K
Article: SCIENTIFIC REPORTS. 2019;9(1):14604
Association of Microcalcification Clusters with Short-term Invasive Breast Cancer Risk and Breast Cancer Risk Factors
Ali MA; Czene K; Hall P; Humphreys K
Article: NATURE COMMUNICATIONS. 2019;10(1):1741
Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer
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Article: STATISTICAL METHODS IN MEDICAL RESEARCH. 2019;28(3):681-702
Modelling breast cancer tumour growth for a stable disease population
Isheden G; Humphreys K
Article: BRITISH JOURNAL OF CANCER. 2019;120(6):647-657
Genome-wide association study of germline variants and breast cancer-specific mortality
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Article: BREAST CANCER RESEARCH. 2019;21(1):8
Localized mammographic density is associated with interval cancer and large breast cancer: a nested case-control study
Strand F; Azavedo E; Hellgren R; Humphreys K; Eriksson M; Shepherd J; Hall P; Czene K
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2019;104(1):21-34
Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes
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Article: JNCI CANCER SPECTRUM. 2018;2(3):pky051
Family History, Reproductive, and Lifestyle Risk Factors for Fibroadenoma and Breast Cancer
Li J; Humphreys K; Ho PJ; Eriksson M; Darai-Ramqvist E; Lindstrom LS; Hall P; Czene K
Article: INTERNATIONAL JOURNAL OF CANCER. 2018;143(5):1093-1104
Time from breast cancer diagnosis to therapeutic surgery and breast cancer prognosis: A population-based cohort study.
Eriksson L; Bergh J; Humphreys K; Wärnberg F; Törnberg S; Czene K
Article: NATURE GENETICS. 2018;50(7):968-978
A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer
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Article: BREAST CANCER RESEARCH. 2018;20(1):31
Long-term prognostic implications of risk factors associated with tumor size: a case study of women regularly attending screening
Strand F; Humphreys K; Holm J; Eriksson M; Tornberg S; Hall P; Azavedo E; Czene K
Article: BREAST CANCER RESEARCH. 2018;20(1):30
Common genetic variation and novel loci associated with volumetric mammographic density
Brand JS; Humphreys K; Li J; Karlsson R; Hall P; Czene K
Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2018;47(2):526-536
Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium
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Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2017;46(6):1814-1822
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Article: NATURE GENETICS. 2017;49(12):1767-1778
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
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Article: NATURE. 2017;551(7678):92-94
Association analysis identifies 65 new breast cancer risk loci
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Article: BREAST CANCER RESEARCH. 2017;19(1):103
Breast Tissue Organisation and its Association with Breast Cancer Risk
Ali MA; Czene K; Eriksson L; Hall P; Humphreys K
Article: JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION : JAMIA. 2017;24(5):950-957
E-Science technologies in a workflow for personalized medicine using cancer screening as a case study
Spjuth O; Karlsson A; Clements M; Humphreys K; Ivansson E; Dowling J; Eklund M; Jauhiainen A; Czene K; Gronberg H; Sparen P; Wiklund F; Cheddad A; Palsdottir P; Rantalainen M; Abrahamsson L; Laure E; Litton J-E; Palmgren J
Article: SCIENTIFIC REPORTS. 2017;7(1):5942
Common shared genetic variation behind decreased risk of breast cancer in celiac disease
Ugalde-Morales E; Li J; Humphreys K; Ludvigsson JF; Yang H; Hall P; Czene K
Article: CLINICAL CANCER RESEARCH. 2017;23(10):2584-2592
Molecular Differences between Screen-Detected and Interval Breast Cancers Are Largely Explained by PAM50 Subtypes
Li J; Ivansson E; Klevebring D; Tobin NP; Lindstrom LS; Holm J; Prochazka G; Cristando C; Palmgren J; Tornberg S; Humphreys K; Hartman J; Frisell J; Rantalainen M; Lindberg J; Hall P; Bergh J; Gronberg H; Czene K
Article: CANCER. 2017;123(3):468-475
Time-dependent risk and predictors of venous thromboembolism in breast cancer patients: A population-based cohort study.
Brand JS; Hedayati E; Bhoo-Pathy N; Bergh J; Hall P; Humphreys K; Ludvigsson JF; Czene K
Article: INTERNATIONAL JOURNAL OF CANCER. 2017;140(1):34-40
Longitudinal fluctuation in mammographic percent density differentiates between interval and screen-detected breast cancer.
Strand F; Humphreys K; Eriksson M; Li J; Andersson TML; Törnberg S; Azavedo E; Shepherd J; Hall P; Czene K
Article: INTERNATIONAL JOURNAL OF CANCER. 2016;139(11):2415-2425
Worse quality of life in young and recently diagnosed breast cancer survivors compared with female survivors of other cancers: A cross-sectional study
Li J; Humphreys K; Eriksson M; Dar H; Brandberg Y; Hall P; Czene K
Article: JOURNAL OF MEDICAL GENETICS. 2016;53(12):800-811
PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS
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Article: CLINICAL CANCER RESEARCH. 2016;22(21):5249-5255
Chemotherapy, Genetic Susceptibility, and Risk of Venous Thromboembolism in Breast Cancer Patients.
Brand JS; Hedayati E; Humphreys K; Ludvigsson JF; Johansson ALV; Bergh J; Hall P; Czene K
Article: BREAST CANCER RESEARCH. 2016;10(1):100
Novel mammographic image features differentiate between interval and screen-detected breast cancer: a case-case study
Strand F; Humphreys K; Cheddad A; Tornberg S; Azavedo E; Shepherd J; Hall P; Czene K
Article: NATURE COMMUNICATIONS. 2016;7:11375
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
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Journal article: JOURNAL OF MEDICAL IMAGING AND HEALTH INFORMATICS. 2016;6(2):380-386
A Combined Segmentation and Registration Framework for Bilateral and Temporal Mammogram Analysis
Khoo DA-A; Li J; Czene K; Hall P; Humphreys K; Law YN
Article: NATURE GENETICS. 2016;48(4):374-386
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170
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Article: CANCER CAUSES AND CONTROL. 2016;27(4):481-491
Assessing within-woman changes in mammographic density: a comparison of fully versus semi-automated area-based approaches
Busana MC; De Stavola BL; Sovio U; Li J; Moss S; Humphreys K; dos-Santos-Silva I
Article: JOURNAL OF CLINICAL ONCOLOGY. 2016;34(3):251-258
Associations of Breast Cancer Risk Prediction Tools With Tumor Characteristics and Metastasis.
Holm J; Li J; Darabi H; Eklund M; Eriksson M; Humphreys K; Hall P; Czene K
Journal article: PROCEDIA COMPUTER SCIENCE. 2016;90:169-174
Spatial Relations of Mammographic Density Regions and their Association with Breast Cancer Risk
Ali MA; Garnier M; Humphreys K
Article: BMC CANCER. 2015;15:978
A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients
Seibold P; Schmezer P; Behrens S; Michailidou K; Bolla MK; Wang Q; Flesch-Janys D; Nevanlinna H; Fagerholm R; Aittomaki K; Blomqvist C; Margolin S; Mannermaa A; Kataja V; Kosma V-M; Hartikainen JM; Lambrechts D; Wildiers H; Kristensen V; Alnaes GG; Nord S; Borresen-Dale A-L; Hooning MJ; Hollestelle A; Jager A; Seynaeve C; Li J; Liu J; Humphreys K; Dunning AM; Rhenius V; Shah M; Kabisch M; Torres D; Ulmer H-U; Hamann U; Schildkraut JM; Purrington KS; Couch FJ; Hall P; Pharoah P; Easton DF; Schmidt MK; Chang-Claude J; Popanda O
Article: NATURE GENETICS. 2015;47(11):1294-1303
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
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Article: JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2015;107(11):djv219
Height and Breast Cancer Risk: Evidence From Prospective Studies and Mendelian Randomization
Zhang B; Shu X-O; Delahanty RJ; Zeng C; Michailidou K; Bolla MK; Wang Q; Dennis J; Wen W; Long J; Li C; Dunning AM; Chang-Claude J; Shah M; Perkins BJ; Czene K; Darabi H; Eriksson M; Bojesen SE; Nordestgaard BG; Nielsen SF; Flyger H; Lambrechts D; Neven P; Wildiers H; Floris G; Schmidt MK; Rookus MA; van den Hurk K; de Kort WLAM; Couch FJ; Olson JE; Hallberg E; Vachon C; Rudolph A; Seibold P; Flesch-Janys D; Peto J; dos-Santos-Silva I; Fletcher O; Johnson N; Nevanlinna H; Muranen TA; Aittomaki K; Blomqvist C; Li J; Humphreys K; Brand J; Guenel P; Truong T; Cordina-Duverger E; Menegaux F; Burwinkel B; Marme F; Yang R; Surowy H; Benitez J; Pilar Zamora M; Perez JIA; Cox A; Cross SS; Reed MWR; Andrulis IL; Knight JA; Glendon G; Tchatchou S; Sawyer EJ; Tomlinson I; Kerin MJ; Miller N; Chenevix-Trench G; Haiman CA; Henderson BE; Schumacher F; Le Marchand L; Lindblom A; Margolin S; Hooning MJ; Martens JWM; Tilanus-Linthorst MMA; Collee JM; Hopper JL; Southey MC; Tsimiklis H; Apicella C; Slager S; Toland AE; Ambrosone CB; Yannoukakos D; Giles GG; Milne RL; McLean C; Fasching PA; Haeberle L; Ekici AB; Beckmann MW; Brenner H; Dieffenbach AK; Arndt V; Stegmaier C; Swerdlow AJ; Ashworth A; Orr N; Jones M; Figueroa J; Garcia-Closas M; Brinton L; Lissowska J; Dumont M; Winqvist R; Pylkas K; Jukkola-Vuorinen A; Grip M; Brauch H; Bruening T; Ko Y-D; Peterlongo P; Manoukian S; Bonanni B; Radice P; Bogdanova N; Antonenkova N; Doerk T; Mannermaa A; Kataja V; Kosma V-M; Hartikainen JM; Devilee P; Seynaeve C; Van Asperen CJ; Jakubowska A; Lubinski J; Jaworska-Bieniek K; Durda K; Hamann U; Torres D; Schmutzler RK; Neuhausen SL; Anton-Culver H; Kristensen VN; Alnaes GIG; Pierce BL; Kraft P; Peters U; Lindstrom S; Seminara D; Burgess S; Ahsan H; Whittemore AS; John EM; Gammon MD; Malone KE; Tessier DC; Vincent D; Bacot F; Luccarini C; Baynes C; Ahmed S; Maranian M; Healey CS; Gonzalez-Neira A; Pita G; Rosario Alonso M; Alvarez N; Herrero D; Pharoah PDP; Simard J; Hall P; Hunter DJ; Easton DF; Zheng W
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2015;97(1):22-34
Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression
Darabi H; Mccue K; Beesley J; Michailidou K; Nord S; Kar S; Humphreys K; Thompson D; Ghoussaini M; Bolla MK; Dennis J; Wang Q; Canisius S; Scott CG; Apicella C; Hopper JL; Southey MC; Stone J; Broeks A; Schmidt MK; Scott RJ; Lophatananon A; Muir K; Beckmann MW; Ekici AB; Fasching PA; Heusinger K; dos-Santos-Silva I; Peto J; Tomlinson I; Sawyer EJ; Burwinkel B; Marme F; Guenel P; Truong T; Bojesen SE; Flyger H; Benitez J; Gonzalez-Neira A; Anton-Culver H; Neuhausen SL; Arndt V; Brenner H; Engel C; Meindl A; Schmutzler RK; Arnold N; Brauch H; Hamann U; Chang-Claude J; Khan S; Nevanlinna H; Ito H; Matsuo K; Bogdanova NV; Doerk T; Lindblom A; Margolin S; Kosma V-M; Mannermaa A; Tseng C-C; Wu AH; Floris G; Lambrechts D; Rudolph A; Peterlongo P; Radice P; Couch FJ; Vachon C; Giles GG; McLean C; Milne RL; Dugue P-A; Haiman CA; Maskarinec G; Woolcott C; Henderson BE; Goldberg MS; Simard J; Teo SH; Mariapun S; Helland A; Haakensen V; Zheng W; Beeghly-Fadiel A; Tamimi R; Jukkola-Vuorinen A; Winqvist R; Andrulis IL; Knight JA; Devilee P; Tollenaar RAEM; Figueroa J; Garcia-Closas M; Czene K; Hooning MJ; Tilanus-Linthorst M; Li J; Gao Y-T; Shu X-O; Cox A; Cross SS; Luben R; Khaw K-T; Choi J-Y; Kang D; Hartman M; Lim WY; Kabisch M; Torres D; Jakubowska A; Lubinski J; McKay J; Sangrajrang S; Toland AE; Yannoukakos D; Shen C-Y; Yu J-C; Ziogas A; Schoemaker MJ; Swerdlow A; Borresen-Dale A-L; Kristensen V; French JD; Edwards SL; Dunning AM; Easton DF; Hal P; Chenevix-Trench G
Article: BREAST CANCER RESEARCH. 2015;17(1):75
Identification of two novel mammographic density loci at 6Q25.1
Brand JS; Li J; Humphreys K; Karlsson R; Eriksson M; Ivansson E; Hall P; Czene K
Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2015;24(6):985-991
Pectoral Muscle Attenuation as a Marker for Breast Cancer Risk in Full-Field Digital Mammography
Cheddad A; Czene K; Hall P; Humphreys K
Article: HUMAN MOLECULAR GENETICS. 2015;24(10):2966-2984
Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2
Orr N; Dudbridge F; Dryden N; Maguire S; Novo D; Perrakis E; Johnson N; Ghoussaini M; Hopper JL; Southey MC; Apicella C; Stone J; Schmidt MK; Broeks A; Van't Veer LJ; Hogervorst FB; Fasching PA; Haeberle L; Ekici AB; Beckmann MW; Gibson L; Aitken Z; Warren H; Sawyer E; Tomlinson I; Kerin MJ; Miller N; Burwinkel B; Marme F; Schneeweiss A; Sohn C; Guenel P; Truong T; Cordina-Duverger E; Sanchez M; Bojesen SE; Nordestgaard BG; Nielsen SF; Flyger H; Benitez J; Zamora MP; Perez JIA; Menendez P; Anton-Culver H; Neuhausen SL; Brenner H; Dieffenbach AK; Arndt V; Stegmaier C; Hamann U; Brauch H; Justenhoven C; Bruning T; Ko Y-D; Nevanlinna H; Aittomaki K; Blomqvist C; Khan S; Bogdanova N; Dork T; Lindblom A; Margolin S; Mannermaa A; Kataja V; Kosma V-M; Hartikainen JM; Chenevix-Trench G; Beesley J; Lambrechts D; Moisse M; Floris G; Beuselinck B; Chang-Claude J; Rudolph A; Seibold P; Flesch-Janys D; Radice P; Peterlongo P; Peissel B; Pensotti V; Couch FJ; Olson JE; Slettedahl S; Vachon C; Giles GG; Milne RL; McLean C; Haiman CA; Henderson BE; Schumacher F; Le Marchand L; Simard J; Goldberg MS; Labreche F; Dumont M; Kristensen V; Alnaes GG; Nord S; Borresen-Dale A-L; Zheng W; Deming-Halverson S; Shrubsole M; Long J; Winqvist R; Pylkas K; Jukkola-Vuorinen A; Grip M; Andrulis IL; Knight JA; Glendon G; Tchatchou S; Devilee P; Tollenaar RAEM; Seynaeve CM; Van Asperen CJ; Garcia-Closas M; Figueroa J; Chanock SJ; Lissowska J; Czene K; Darabi H; Eriksson M; Klevebring D; Hooning MJ; Hollestelle A; van Deurzen CHM; Kriege M; Hall P; Li J; Liu J; Humphreys K; Cox A; Cross SS; Reed MWR; Pharoah PDP; Dunning AM; Shah M; Perkins BJ; Jakubowska A; Lubinski J; Jaworska-Bieniek K; Durda K; Ashworth A; Swerdlow A; Jones M; Schoemaker MJ; Meindl A; Schmutzler RK; Olswold C; Slager S; Toland AE; Yannoukakos D; Muir K; Lophatananon A; Stewart-Brown S; Siriwanarangsan P; Matsuo K; Ito H; Iwata H; Ishiguro J; Wu AH; Tseng C-C; Van den Berg D; Stram DO; Teo SH; Yip CH; Kang P; Ikram MK; Shu X-O; Lu W; Gao Y-T; Cai H; Kang D; Choi J-Y; Park SK; Noh D-Y; Hartman M; Miao H; Lim WY; Lee SC; Sangrajrang S; Gaborieau V; Brennan P; McKay J; Wu P-E; Hou M-F; Yu J-C; Shen C-Y; Blot W; Cai Q; Signorello LB; Luccarini C; Bayes C; Ahmed S; Maranian M; Healey CS; Gonzalez-Neira A; Pita G; Alonso MR; Alvarez N; Herrero D; Tessier DC; Vincent D; Bacot F; Hunter DJ; Lindstrom S; Dennis J; Michailidou K; Bolla MK; Easton DF; Silva IDS; Fletcher O; Peto J
Article: JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2015;107(5):djv081
Identification of Novel Genetic Markers of Breast Cancer Survival
Guo Q; Schmidt MK; Kraft P; Canisius S; Chen C; Khan S; Tyrer J; Bolla MK; Wang Q; Dennis J; Michailidou K; Lush M; Kar S; Beesley J; Dunning AM; Shah M; Czene K; Darabi H; Eriksson M; Lambrechts D; Weltens C; Leunen K; Bojesen SE; Nordestgaard BG; Nielsen SF; Flyger H; Chang-Claude J; Rudolph A; Seibold P; Flesch-Janys D; Blomqvist C; Aittomaeki K; Fagerholm R; Muranen TA; Couch FJ; Olson JE; Vachon C; Andrulis IL; Knight JA; Glendon G; Mulligan AM; Broeks A; Hogervorst FB; Haiman CA; Henderson BE; Schumacher F; Le Marchand L; Hopper JL; Tsimiklis H; Apicella C; Southey MC; Cox A; Cross SS; Reed MWR; Giles GG; Milne RL; McLean C; Winqvist R; Pylkaes K; Jukkola-Vuorinen A; Grip M; Hooning MJ; Hollestelle A; Martens JWM; Van den Ouweland AMW; Marme F; Schneeweiss A; Yang R; Burwinkel B; Figueroa J; Chanock SJ; Lissowska J; Sawyer EJ; Tomlinson I; Kerin MJ; Miller N; Brenner H; Dieffenbach AK; Arndt V; Holleczek B; Mannermaa A; Kataja V; Kosma V-M; Hartikainen JM; Li J; Brand JS; Humphreys K; Devilee P; Tollenaar RAEM; Seynaeve C; Radice P; Peterlongo P; Bonanni B; Mariani P; Fasching PA; Beckmann MW; Hein A; Ekici AB; Chenevix-Trench G; Balleine R; Phillips K-A; Benitez J; Zamora MP; Perez JIA; Menendez P; Jakubowska A; Lubinski J; Jaworska-Bieniek K; Durda K; Hamann U; Kabisch M; Ulmer HU; Ruediger T; Margolin S; Kristensen V; Nord S; Evans DG; Abraham JE; Earl HM; Hiller L; Dunn JA; Bowden S; Berg C; Campa D; Diver WR; Gapstur SM; Gaudet MM; Hankinson SE; Hoover RN; Huesing A; Kaaks R; Machiela MJ; Willett W; Barrdahl M; Canzian F; Chin S-F; Caldas C; Hunter DJ; Lindstrom S; Garcia-Closas M; Hall P; Easton DF; Eccles DM; Rahman N; Nevanlinna H; Pharoah PDP
Article: JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2015;107(5):djv036
Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants
Mavaddat N; Pharoah PDP; Michailidou K; Tyrer J; Brook MN; Bolla MK; Wang Q; Dennis J; Dunning AM; Shah M; Luben R; Brown J; Bojesen SE; Nordestgaard BG; Nielsen SF; Flyger H; Czene K; Darabi H; Eriksson M; Peto J; dos-Santos-Silva I; Dudbridge F; Johnson N; Schmidt MK; Broeks A; Verhoef S; Rutgers EJ; Swerdlow A; Ashworth A; Orr N; Schoemaker MJ; Figueroa J; Chanock SJ; Brinton L; Lissowska J; Couch FJ; Olson JE; Vachon C; Pankratz VS; Lambrechts D; Wildiers H; Van Ongeval C; Van Limbergen E; Kristensen V; Alnaes GG; Nord S; Borresen-Dale A-L; Nevanlinna H; Muranen TA; Aittomaeki K; Blomqvist C; Chang-Claude J; Rudolph A; Seibold P; Flesch-Janys D; Fasching PA; Haeberle L; Ekici AB; Beckmann MW; Burwinkel B; Marme F; Schneeweiss A; Sohn C; Trentham-Dietz A; Newcomb P; Titus L; Egan KM; Hunter DJ; Lindstrom S; Tamimi RM; Kraft P; Rahman N; Turnbull C; Renwick A; Seal S; Li J; Liu J; Humphreys K; Benitez J; Zamora MP; Perez JIA; Menendez P; Jakubowska A; Lubinski J; Jaworska-Bieniek K; Durda K; Bogdanova NV; Antonenkova NN; Doerk T; Anton-Culver H; Neuhausen SL; Ziogas A; Bernstein L; Devilee P; Tollenaar RAEM; Seynaeve C; van Asperen CJ; Cox A; Cross SS; Reed MWR; Khusnutdinova E; Bermisheva M; Prokofyeva D; Takhirova Z; Meindl A; Schmutzler RK; Sutter C; Yang R; Schuermann P; Bremer M; Christiansen H; Park-Simon T-W; Hillemanns P; Guenel P; Truong T; Menegaux F; Sanchez M; Radice P; Peterlongo P; Manoukian S; Pensotti V; Hopper JL; Tsimiklis H; Apicella C; Southey MC; Brauch H; Bruening T; Ko Y-D; Sigurdson AJ; Doody MM; Hamann U; Torres D; Ulmer H-U; Foersti A; Sawyer EJ; Tomlinson I; Kerin MJ; Miller N; Andrulis IL; Knight JA; Glendon G; Mulligan AM; Chenevix-Trench G; Balleine R; Giles GG; Milne RL; McLean C; Lindblom A; Margolin S; Haiman CA; Henderson BE; Schumacher F; Le Marchand L; Eilber U; Wang-Gohrke S; Hooning MJ; Hollestelle A; van den Ouweland AMW; Koppert LB; Carpenter J; Clarke C; Scott R; Mannermaa A; Kataja V; Kosma V-M; Hartikainen JM; Brenner H; Arndt V; Stegmaier C; Dieffenbach AK; Winqvist R; Pylkaes K; Jukkola-Vuorinen A; Grip M; Offit K; Vijai J; Robson M; Rau-Murthy R; Dwek M; Swann R; Perkins KA; Goldberg MS; Labreche F; Dumont M; Eccles DM; Tapper WJ; Rafiq S; John EM; Whittemore AS; Slager S; Yannoukakos D; Toland AE; Yao S; Zheng W; Halverson SL; Gonzalez-Neira A; Pita G; Alonso MR; Alvarez N; Herrero D; Tessier DC; Vincent D; Bacot F; Luccarini C; Baynes C; Ahmed S; Maranian M; Healey CS; Simard J; Hall P; Easton DF; Garcia-Closas M
Article: BREAST CANCER RESEARCH. 2015;17(1):58
Common germline polymorphisms associated with breast cancer-specific survival
Pirie A; Guo Q; Kraft P; Canisius S; Eccles DM; Rahman N; Nevanlinna H; Chen C; Khan S; Tyrer J; Bolla MK; Wang Q; Dennis J; Michailidou K; Lush M; Dunning AM; Shah M; Czene K; Darabi H; Eriksson M; Lambrechts D; Weltens C; Leunen K; van Ongeval C; Nordestgaard BG; Nielsen SF; Flyger H; Rudolph A; Seibold P; Flesch-Janys D; Blomqvist C; Aittomaki K; Fagerholm R; Muranen TA; Olsen JE; Hallberg E; Vachon C; Knight JA; Glendon G; Mulligan AM; Broeks A; Cornelissen S; Haiman CA; Henderson BE; Schumacher F; Le Marchand L; Hopper JL; Tsimiklis H; Apicella C; Southey MC; Cross SS; Reed MWR; Giles GG; Milne RL; McLean C; Winqvist R; Pylkas K; Jukkola-Vuorinen A; Grip M; Hooning MJ; Hollestelle A; Martens JWM; van den Ouweland AMW; Marme F; Schneeweiss A; Yang R; Burwinkel B; Figueroa J; Chanock SJ; Lissowska J; Sawyer EJ; Tomlinson I; Kerin MJ; Miller N; Brenner H; Butterbach K; Holleczek B; Kataja V; Kosma V-M; Hartikainen JM; Li J; Brand JS; Humphreys K; Devilee P; Tollenaar RAEM; Seynaeve C; Radice P; Peterlongo P; Manoukian S; Ficarazzi F; Beckmann MW; Hein A; Ekici AB; Balleine R; Phillips K-A; Benitez J; Zamora MP; Perez JIA; Menendez P; Jakubowska A; Lubinski J; Gronwald J; Durda K; Hamann U; Kabisch M; Ulmer HU; Ruediger T; Margolin S; Kristensen V; Nord S; Evans DG; Abraham J; Earl H; Poole CJ; Hiller L; Dunn JA; Bowden S; Yang R; Campa D; Diver WR; Gapstur SM; Gaudet MM; Hankinson S; Hoover RN; Husing A; Kaaks R; Machiela MJ; Willett W; Barrdahl M; Canzian F; Chin S-F; Caldas C; Hunter DJ; Lindstrom S; Garcia-Closas M; Couch FJ; Chenevix-Trench G; Mannermaa A; Andrulis IL; Hall P; Chang-Claude J; Easton DF; Bojesen SE; Cox A; Fasching PA; Pharoah PDP; Schmidt MK
Article: NATURE GENETICS. 2015;47(4):373-380
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
Michailidou K; Beesley J; Lindstrom S; Canisius S; Dennis J; Lush MJ; Maranian MJ; Bolla MK; Wang Q; Shah M; Perkins BJ; Czene K; Eriksson M; Darabi H; Brand JS; Bojesen SE; Nordestgaard BG; Flyger H; Nielsen SF; Rahman N; Turnbull C; Fletcher O; Peto J; Gibson L; dos-Santos-Silva I; Chang-Claude J; Flesch-Janys D; Rudolph A; Eilber U; Behrens S; Nevanlinna H; Muranen TA; Aittomaki K; Blomqvist C; Khan S; Aaltonen K; Ahsan H; Kibriya MG; Whittemore AS; John EM; Malone KE; Gammon MD; Santella RM; Ursin G; Makalic E; Schmidt DF; Casey G; Hunter DJ; Gapstur SM; Gaudet MM; Diver WR; Haiman CA; Schumacher F; Henderson BE; Le Marchand L; Berg CD; Chanock SJ; Figueroa J; Hoover RN; Lambrechts D; Neven P; Wildiers H; van Limbergen E; Schmidt MK; Broeks A; Verhoef S; Cornelissen S; Couch FJ; Olson JE; Hallberg E; Vachon C; Waisfisz Q; Meijers-Heijboer H; Adank MA; van der Luijt RB; Li J; Liu J; Humphreys K; Kang D; Choi J-Y; Park SK; Yoo K-Y; Matsuo K; Ito H; Iwata H; Tajima K; Guenel P; Truong T; Mulot C; Sanchez M; Burwinkel B; Marme F; Surowy H; Sohn C; Wu AH; Tseng C-C; Van den Berg D; Stram DO; Gonzalez-Neira A; Benitez J; Zamora MP; Arias Perez JI; Shu X-O; Lu W; Gao Y-T; Cai H; Cox A; Cross SS; Reed MWR; Andrulis IL; Knight JA; Glendon G; Mulligan AM; Sawyer EJ; Tomlinson I; Kerin MJ; Miller N; Lindblom A; Margolin S; Teo SH; Yip CH; Taib NAM; Tan G-H; Hooning MJ; Hollestelle A; Martens JWM; Collee JM; Blot W; Signorello LB; Cai Q; Hopper JL; Southey MC; Tsimiklis H; Apicella C; Shen C-Y; Hsiung C-N; Wu P-E; Hou M-F; Kristensen VN; Nord S; Alnaes GIG; Giles GG; Milne RL; McLean C; Canzian F; Trichopoulos D; Peeters P; Lund E; Sund M; Khaw K-T; Gunter MJ; Palli D; Mortensen LM; Dossus L; Huerta J-M; Meindl A; Schmutzler RK; Sutter C; Yang R; Muir K; Lophatananon A; Stewart-Brown S; Siriwanarangsan P; Hartman M; Miao H; Chia KS; Chan CW; Fasching PA; Hein A; Beckmann MW; Haeberle L; Brenner H; Dieffenbach AK; Arndt V; Stegmaier C; Ashworth A; Orr N; Schoemaker MJ; Swerdlow AJ; Brinton L; Garcia-Closas M; Zheng W; Halverson SL; Shrubsole M; Long J; Goldberg MS; Labreche F; Dumont M; Winqvist R; Pylkas K; Jukkola-Vuorinen A; Grip M; Brauch H; Hamann U; Bruening T; Radice P; Peterlongo P; Manoukian S; Bernard L; Bogdanova NV; Doerk T; Mannermaa A; Kataja V; Kosma V-M; Hartikainen JM; Devilee P; Tollenaar RAEM; Seynaeve C; Van Asperen CJ; Jakubowska A; Lubinski J; Jaworska K; Huzarski T; Sangrajrang S; Gaborieau V; Brennan P; Mckay J; Slager S; Toland AE; Ambrosone CB; Yannoukakos D; Kabisch M; Torres D; Neuhausen SL; Anton-Culver H; Luccarini C; Baynes C; Ahmed S; Healey CS; Tessier DC; Vincent D; Bacot F; Pita G; Rosario Alonso M; Alvarez N; Herrero D; Simard J; Pharoah PPDP; Kraft P; Dunning AM; Chenevix-Trench G; Hall P; Easton DF
Article: JOURNAL OF CLINICAL ONCOLOGY. 2015;33(9):1030-1037
Risk factors and tumor characteristics of interval cancers by mammographic density.
Holm J; Humphreys K; Li J; Ploner A; Cheddad A; Eriksson M; Törnberg S; Hall P; Czene K
Article: INTERNATIONAL JOURNAL OF CANCER. 2015;136(6):E685-E696
Investigation of gene-environment interactions between 47 newly identified breast cancer susceptibility loci and environmental risk factors
Rudolph A; Milne RL; Truong T; Knight JA; Seibold P; Flesch-Janys D; Behrens S; Eilber U; Bolla MK; Wang Q; Dennis J; Dunning AM; Shah M; Munday HR; Darabi H; Eriksson M; Brand JS; Olson J; Vachon CM; Hallberg E; Esteban Castelao J; Carracedo A; Torres M; Li J; Humphreys K; Cordina-Duverger E; Menegaux F; Flyger H; Nordestgaard BG; Nielsen SF; Yesilyurt BT; Floris G; Leunen K; Engelhardt EG; Broeks A; Rutgers EJ; Glendon G; Mulligan AM; Cross S; Reed M; Gonzalez-Neira A; Arias Perez JI; Provenzano E; Apicella C; Southey MC; Spurdle A; Haeberle L; Beckmann MW; Ekici AB; Dieffenbach AK; Arndt V; Stegmaier C; McLean C; Baglietto L; Chanock SJ; Lissowska J; Sherman ME; Bruening T; Hamann U; Ko Y-D; Orr N; Schoemaker M; Ashworth A; Kosma V-M; Kataja V; Hartikainen JM; Mannermaa A; Swerdlow A; Giles GG; Brenner H; Fasching PA; Chenevix-Trench G; Hopper J; Benitez J; Cox A; Andrulis IL; Lambrechts D; Gago-Dominguez M; Couch F; Czene K; Bojesen SE; Easton DF; Schmidt MK; Guenel P; Hall P; Pharoah PDP; Garcia-Closas M; Chang-Claude J
Article: BREAST CANCER RESEARCH. 2015;17(1):18
Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy
Lei J; Rudolph A; Moysich KB; Rafiq S; Behrens S; Goode EL; Pharoah PP; Seibold P; Fasching PA; Andrulis IL; Kristensen VN; Couch FJ; Hamann U; Hooning MJ; Nevanlinna H; Eilber U; Bolla MK; Dennis J; Wang Q; Lindblom A; Mannermaa A; Lambrechts D; Garcia-Closas M; Hall P; Chenevix-Trench G; Shah M; Luben R; Haeberle L; Ekici AB; Beckmann MW; Knight JA; Glendon G; Tchatchou S; Alnaes GIG; Borresen-Dale A-L; Nord S; Olson JE; Hallberg E; Vachon C; Torres D; Ulmer H-U; Ruediger T; Jager A; van Deurzen CH; Tilanus-Linthorst MM; Muranen TA; Aittomaki K; Blomqvist C; Margolin S; Kosma V-M; Hartikainen JM; Kataja V; Hatse S; Wildiers H; Smeets A; Figueroa J; Chanock SJ; Lissowska J; Li J; Humphreys K; Phillips K-A; Linn S; Cornelissen S; van den Broek SAJ; Kang D; Choi J-Y; Park SK; Yoo K-Y; Hsiung C-N; Wu P-E; Hou M-F; Shen C-Y; Teo SH; Taib NAM; Yip CH; Ho GF; Matsuo K; Ito H; Iwata H; Tajima K; Dunning AM; Benitez J; Czene K; Sucheston LE; Maishman T; Tapper WJ; Eccles D; Easton DF; Schmidt MK; Chang-Claude J
Article: CARCINOGENESIS. 2015;36(2):256-271
Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer
Kabisch M; Bermejo JL; Duennebier T; Ying S; Michailidou K; Bolla MK; Wang Q; Dennis J; Shah M; Perkins BJ; Czene K; Darabi H; Eriksson M; Bojesen SE; Nordestgaard BG; Nielsen SF; Flyger H; Lambrechts D; Neven P; Peeters S; Weltens C; Couch FJ; Olson JE; Wang X; Purrington K; Chang-Claude J; Rudolph A; Seibold P; Flesch-Janys D; Peto J; dos-Santos-Silva I; Johnson N; Fletcher O; Nevanlinna H; Muranen TA; Aittomaki K; Blomqvist C; Schmidt MK; Broeks A; Cornelissen S; Hogervorst FBL; Li J; Brand JS; Humphreys K; Guenel P; Truong T; Menegaux F; Sanchez M; Burwinkel B; Marme F; Yang R; Bugert P; Gonzalez-Neira A; Benitez J; Pilar Zamora M; Arias Perez JI; Cox A; Cross SS; Reed MWR; Andrulis IL; Knight JA; Glendon G; Tchatchou S; Sawyer EJ; Tomlinson I; Kerin MJ; Miller N; Haiman CA; Schumacher F; Henderson BE; Le Marchand L; Lindblom A; Margolin S; Hooning MJ; Hollestelle A; Kriege M; Koppert LB; Hopper JL; Southey MC; Tsimiklis H; Apicella C; Slettedahl S; Toland AE; Vachon C; Yannoukakos D; Giles GG; Milne RL; McLean C; Fasching PA; Ruebner M; Ekici AB; Beckmann MW; Brenner H; Dieffenbach AK; Arndt V; Stegmaier C; Ashworth A; Orr N; Schoemaker MJ; Swerdlow A; Garcia-Closas M; Figueroa J; Chanock SJ; Lissowska J; Goldberg MS; Labreche F; Dumont M; Winqvist R; Pylkas K; Jukkola-Vuorinen A; Grip M; Brauch H; Bruening T; Ko Y-D; Radice P; Peterlongo P; Scuvera G; Fortuzzi S; Bogdanova N; Doerk T; Mannermaa A; Kataja V; Kosma V-M; Hartikainen JM; Devilee P; Tollenaar RAEM; Seynaeve C; Van Asperen CJ; Jakubowska A; Lubinski J; Jaworska-Bieniek K; Durda K; Zheng W; Shrubsole MJ; Cai Q; Torres D; Anton-Culver H; Kristensen V; Bacot F; Tessier DC; Vincent D; Luccarini C; Baynes C; Ahmed S; Maranian M; Simard J; Chenevix-Trench G; Hall P; Pharoah PDP; Dunning AM; Easton DF; Hamann U
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2015;96(1):5-20
Fine-Scale Mapping of the 5q11.2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K1
Glubb DM; Maranian MJ; Michailidou K; Pooley KA; Meyer KB; Kar S; Carlebur S; O'Reilly M; Betts JA; Hillman KM; Kaufmann S; Beesley J; Canisius S; Hopper JL; Southey MC; Tsimiklis H; Apicella C; Schmidt MK; Broeks A; Hogervorst FB; van der Schoot CE; Muir K; Lophatananon A; Stewart-Brown S; Siriwanarangsan P; Fasching PA; Ruebner M; Ekici AB; Beckmann MW; Peto J; Dos-Santos-Silva I; Fletcher O; Johnson N; Pharoah PDP; Bolla MK; Wang Q; Dennis J; Sawyer EJ; Tomlinson I; Kerin MJ; Miller N; Burwinkel B; Marme F; Yang R; Surowy H; Guenel P; Truong T; Menegaux F; Sanchez M; Bojesen SE; Nordestgaard BG; Nielsen SF; Flyger H; Gonzalez-Neira A; Benitez J; Pilar Zamora M; Arias Perez JI; Anton-Culver H; Neuhausen SL; Brenner H; Dieffenbach AK; Arndt V; Stegmaier C; Meindl A; Schmutzler RK; Brauch H; Ko Y-D; Bruening T; Nevanlinna H; Muranen TA; Aittomaeki K; Blomqvist C; Matsuo K; Ito H; Iwata H; Tanaka H; Doerk T; Bogdanova NV; Helbig S; Lindblom A; Margolin S; Mannermaa A; Kataja V; Kosma V-M; Hartikainen JM; Wu AH; Tseng C-C; Van den Berg D; Stram DO; Lambrechts D; Zhao H; Weltens C; van Limbergen E; Chang-Claude J; Flesch-Janys D; Rudolph A; Seibold P; Radice P; Peterlongo P; Barile M; Capra F; Couch FJ; Olson JE; Hallberg E; Vachon C; Giles GG; Milne RL; McLean C; Haiman CA; Henderson BE; Schumacher F; Le Marchand L; Simard J; Goldberg MS; Labreche F; Dumont M; Teo SH; Yip CH; See M-H; Cornes B; Cheng C-Y; Ikram MK; Kristensen V; Zheng W; Halverson SL; Shrubsole M; Long J; Winqvist R; Pylkaes K; Jukkola-Vuorinen A; Kauppila S; Andrulis IL; Knight JA; Glendon G; Tchatchou S; Devilee P; Tollenaar RAEM; Seynaeve C; Van Asperen CJ; Garcia-Closas M; Figueroa J; Chanock SJ; Lissowska J; Czene K; Klevebring D; Darabi H; Eriksson M; Hooning MJ; Hollestelle A; Martens JWM; Collee JM; Hall P; Li J; Humphreys K; Shu X-O; Lu W; Gao Y-T; Cai H; Cox A; Cross SS; Reed MWR; Blot W; Signorello LB; Cai Q; Shah M; Ghoussaini M; Kang D; Choi J-Y; Park SK; Noh D-Y; Hartman M; Miao H; Lim WY; Tang A; Hamann U; Torres D; Jakubowska A; Lubinski J; Jaworska K; Durda K; Sangrajrang S; Gaborieau V; Brennan P; McKay J; Olswold C; Slager S; Toland AE; Yannoukakos D; Shen C-Y; Wu P-E; Yu J-C; Hou M-F; Swerdlow A; Ashworth A; Orr N; Jones M; Pita G; Rosario Alonso M; Alvarez N; Herrero D; Tessier DC; Vincent D; Bacot F; Luccarini C; Baynes C; Ahmed S; Healey CS; Brown MA; Ponder BAJ; Chenevix-Trench G; Thompson DJ; Edwards SL; Easton DF; Dunning AM; French JD
Article: HUMAN MOLECULAR GENETICS. 2015;24(1):285-298
Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk
Lin W-Y; Camp NJ; Ghoussaini M; Beesley J; Michailidou K; Hopper JL; Apicella C; Southey MC; Stone J; Schmidt MK; Broeks A; Van't Veer LJ; Rutgers EJT; Muir K; Lophatananon A; Stewart-Brown S; Siriwanarangsan P; Fasching PA; Haeberle L; Ekici AB; Beckmann MW; Peto J; Dos-Santos-Silva I; Fletcher O; Johnson N; Bolla MK; Wang Q; Dennis J; Sawyer EJ; Cheng T; Tomlinson I; Kerin MJ; Miller N; Marme F; Surowy HM; Burwinkel B; Guenel P; Truong T; Menegaux F; Mulot C; Bojesen SE; Nordestgaard BG; Nielsen SF; Flyger H; Benitez J; Zamora MP; Arias Perez JI; Menendez P; Gonzalez-Neira A; Pita G; Rosario Alonso M; Alvarez N; Herrera D; Anton-Culver H; Brenner H; Dieffenbach AK; Arndt V; Stegmaier C; Meindl A; Lichtner P; Schmutzler RK; Mueller-Myhsok B; Brauch H; Bruening T; Ko Y-D; Tessier DC; Vincent D; Bacot F; Nevanlinna H; Aittomaeki K; Blomqvist C; Khan S; Matsuo K; Ito H; Iwata H; Horio A; Bogdanova NV; Antonenkova NN; Doerk T; Lindblom A; Margolin S; Mannermaa A; Kataja V; Kosma V-M; Hartikainen JM; Wu AH; Tseng C-C; Van den Berg D; Stram DO; Neven P; Wauters E; Wildiers H; Lambrechts D; Chang-Claude J; Rudolph A; Seibold P; Flesch-Janys D; Radice P; Peterlongo P; Manoukian S; Bonanni B; Couch FJ; Wang X; Vachon C; Purrington K; Giles GG; Milne RL; Mclean C; Haiman CA; Henderson BE; Schumacher F; Le Marchand L; Simard J; Goldberg MS; Labreche F; Dumont M; Teo SH; Yip CH; Hassan N; Vithana EN; Kristensen V; Zheng W; Deming-Halverson S; Shrubsole MJ; Long J; Winqvist R; Pylkaes K; Jukkola-Vuorinen A; Kauppila S; Andrulis IL; Knight JA; Glendon G; Tchatchou S; Devilee P; Tollenaar RAEM; Seynaeve C; Van Asperen CJ; Garcia-Closas M; Figueroa J; Lissowska J; Brinton L; Czene K; Darabi H; Eriksson M; Brand JS; Hooning MJ; Hollestelle A; Van den Ouweland AMW; Jager A; Li J; Liu J; Humphreys K; Shu X-O; Lu W; Gao Y-T; Cai H; Cross SS; Reed MWR; Blot W; Signorello LB; Cai Q; Pharoah PDP; Perkins B; Shah M; Blows FM; Kang D; Yoo K-Y; Noh D-Y; Hartman M; Miao H; Chia KS; Putti TC; Hamann U; Luccarini C; Baynes C; Ahmed S; Maranian M; Healey CS; Jakubowska A; Lubinski J; Jaworska-Bieniek K; Durda K; Sangrajrang S; Gaborieau V; Brennan P; Mckay J; Slager S; Toland AE; Yannoukakos D; Shen C-Y; Hsiung C-N; Wu P-E; Ding S-L; Ashworth A; Jones M; Orr N; Swerdlow AJ; Tsimiklis H; Makalic E; Schmidt DF; Bui QM; Chanock SJ; Hunter DJ; Hein R; Dahmen N; Beckmann L; Aaltonen K; Muranen TA; Heikkinen T; Irwanto A; Rahman N; Turnbull CA; Waisfisz Q; Meijers-Heijboer HEJ; Adank MA; Van der Luijt RB; Hall P; Chenevix-Trench G; Dunning A; Easton DF; Cox A
Article: HUMAN MOLECULAR GENETICS. 2014;23(22):6034-6046
Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade
Purrington KS; Slettedahl S; Bolla MK; Michailidou K; Czene K; Nevanlinna H; Bojesen SE; Andrulis IL; Cox A; Hall P; Carpenter J; Yannoukakos D; Haiman CA; Fasching PA; Mannermaa A; Winqvist R; Brenner H; Lindblom A; Chenevix-Trench G; Benitez J; Swerdlow A; Kristensen V; Guenel P; Meindl A; Darabi H; Eriksson M; Fagerholm R; Aittomaki K; Blomqvist C; Nordestgaard BG; Nielsen SF; Flyger H; Wang X; Olswold C; Olson JE; Mulligan AM; Knight JA; Tchatchou S; Reed MWR; Cross SS; Liu J; Li J; Humphreys K; Clarke C; Scott R; Fostira F; Fountzilas G; Konstantopoulou I; Henderson BE; Schumacher F; Le Marchand L; Ekici AB; Hartmann A; Beckmann MW; Hartikainen JM; Kosma V-M; Kataja V; Jukkola-Vuorinen A; Pylkas K; Kauppila S; Dieffenbach AK; Stegmaier C; Arndt V; Margolin S; Balleine R; Arias Perez JI; Pilar Zamora M; Menendez P; Ashworth A; Jones M; Orr N; Arveux P; Kerbrat P; Therese T; Bugert P; Toland AE; Ambrosone CB; Labreche F; Goldberg MS; Dumont M; Ziogas A; Lee E; Dite GS; Apicella C; Southey MC; Long J; Shrubsole M; Deming-Halverson S; Ficarazzi F; Barile M; Peterlongo P; Durda K; Jaworska-Bieniek K; Tollenaar RAEM; Seynaeve C; Bruening T; Ko Y-D; Van Deurzen CHM; Martens JWM; Kriege M; Figueroa JD; Chanock SJ; Lissowska J; Tomlinson I; Kerin MJ; Miller N; Schneeweiss A; Tapper WJ; Gerty SM; Durcan L; Mclean C; Milne RL; Baglietto L; Silva IDS; Fletcher O; Johnson N; Van'T Veer LJ; Cornelissen S; Foersti A; Torres D; Ruediger T; Rudolph A; Flesch-Janys D; Nickels S; Weltens C; Floris G; Moisse M; Dennis J; Wang Q; Dunning AM; Shah M; Brown J; Simard J; Anton-Culver H; Neuhausen SL; Hopper JL; Bogdanova N; Doerk T; Zheng W; Radice P; Jakubowska A; Lubinski J; Devillee P; Brauch H; Hooning M; Garcia-Closas M; Sawyer E; Burwinkel B; Marmee F; Eccles DM; Giles GG; Peto J; Schmidt M; Broeks A; Hamann U; Chang-Claude J; Lambrechts D; Pharoah PDP; Easton D; Pankratz VS; Slager S; Vachon CM; Couch FJ
Article: HUMAN MOLECULAR GENETICS. 2014;23(22):6096-6111
Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium
Milne RL; Burwinkel B; Michailidou K; Arias-Perez J-I; Pilar Zamora M; Menendez-Rodriguez P; Hardisson D; Mendiola M; Gonzalez-Neira A; Pita G; Rosario Alonso M; Dennis J; Wang Q; Bolla MK; Swerdlow A; Ashworth A; Orr N; Schoemaker M; Ko Y-D; Brauch H; Hamann U; Andrulis IL; Knight JA; Glendon G; Tchatchou S; Matsuo K; Ito H; Iwata H; Tajima K; Li J; Brand JS; Brenner H; Dieffenbach AK; Arndt V; Stegmaier C; Lambrechts D; Peuteman G; Christiaens M-R; Smeets A; Jakubowska A; Lubinski J; Jaworska-Bieniek K; Durda K; Hartman M; Hui M; Lim WY; Chan CW; Marme F; Yang R; Bugert P; Lindblom A; Margolin S; Garcia-Closas M; Chanock SJ; Lissowska J; Figueroa JD; Bojesen SE; Nordestgaard BG; Flyger H; Hooning MJ; Kriege M; van den Ouweland AMW; Koppert LB; Fletcher O; Johnson N; dos-Santos-Silva I; Peto J; Zheng W; Deming-Halverson S; Shrubsole MJ; Long J; Chang-Claude J; Rudolph A; Seibold P; Flesch-Janys D; Winqvist R; Pylkas K; Jukkola-Vuorinen A; Grip M; Cox A; Cross SS; Reed MWR; Schmidt MK; Broeks A; Cornelissen S; Braaf L; Kang D; Choi J-Y; Park SK; Noh D-Y; Simard J; Dumont M; Goldberg MS; Labreche F; Fasching PA; Hein A; Ekici AB; Beckmann MW; Radice P; Peterlongo P; Azzollini J; Barile M; Sawyer E; Tomlinson I; Kerin M; Miller N; Hopper JL; Schmidt DF; Makalic E; Southey MC; Teo SH; Yip CH; Sivanandan K; Tay W-T; Shen C-Y; Hsiung C-N; Yu J-C; Hou M-F; Guenel P; Therese T; Sanchez M; Mulot C; Blot W; Cai Q; Nevanlinna H; Muranen TA; Aittomaki K; Blomqvist C; Wu AH; Tseng C-C; Van den Berg D; Stram DO; Bogdanova N; Doerk T; Muir K; Lophatananon A; Stewart-Brown S; Siriwanarangsan P; Mannermaa A; Kataja V; Kosma V-M; Hartikainen JM; Shu X-O; Lu W; Gao Y-T; Zhang B; Couch FJ; Toland AE; Yannoukakos D; Sangrajrang S; McKay J; Wang X; Olson JE; Vachon C; Purrington K; Severi G; Baglietto L; Haiman CA; Henderson BE; Schumacher F; Le Marchand L; Devilee P; Tollenaar RAEM; Seynaeve C; Czene K; Eriksson M; Humphreys K; Darabi H; Ahmed S; Shah M; Pharoah PDP; Hall P; Giles GG; Benitez J; Dunning AM; Chenevix-Trench G; Easton DF
Article: JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2014;106(12):dju334
Volumetric Mammographic Density: Heritability and Association With Breast Cancer Susceptibility Loci
Brand JS; Humphreys K; Thompson DJ; Li J; Eriksson M; Hall P; Czene K
Article: BMC MEDICAL GENETICS. 2014;15:113
A comprehensive evaluation of the role of genetic variation in follicular lymphoma survival
Baecklund F; Foo J-N; Bracci P; Darabi H; Karlsson R; Hjalgrim H; Rosenquist R; Adami H-O; Glimelius B; Melbye M; Conde L; Liu J; Humphreys K; Skibola CF; Smedby KE
Article: NATURE COMMUNICATIONS. 2014;5:4999
Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation
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Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2014;23(9):1764-1772
Automated Measurement of Volumetric Mammographic Density: A Tool for Widespread Breast Cancer Risk Assessment
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Article: NATURE COMMUNICATIONS. 2014;5:4051
2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy
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Article: BRITISH JOURNAL OF CANCER. 2014;110(7):1908-1916
Comparison of fully and semi-automated area-based methods for measuring mammographic density and predicting breast cancer risk
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Article: PLOS GENETICS. 2014;10(4):e1004285
Genetic Predisposition to In Situ and Invasive Lobular Carcinoma of the Breast
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Article: HUMAN MOLECULAR GENETICS. 2014;23(7):1934-1946
A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46 450 cases and 42 461 controls from the breast cancer association consortium
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Article: BRITISH JOURNAL OF CANCER. 2014;110(4):1088-1100
FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium
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Article: PLOS ONE. 2014;9(11):e109973
MicroRNA Related Polymorphisms and Breast Cancer Risk
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Article: PLOS ONE. 2014;9(10):e110690
Area and Volumetric Density Estimation in Processed Full-Field Digital Mammograms for Risk Assessment of Breast Cancer
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Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2013;93(6):1046-1060
Fine-Scale Mapping of the FGFR2 Breast Cancer Risk Locus: Putative Functional Variants Differentially Bind FOXA1 and E2F1
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Article: JOURNAL OF MEDICAL GENETICS. 2013;50(10):666-673
Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size
Li J; Foo JN; Schoof N; Varghese JS; Fernandez-Navarro P; Gierach GL; Quek ST; Hartman M; Nord S; Kristensen VN; Pollan M; Figueroa JD; Thompson DJ; Li Y; Khor CC; Humphreys K; Liu J; Czene K; Hall P
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2013;93(1):167-172
Coding Variants at Hexa-allelic Amino Acid 13 of HLA-DRB1 Explain Independent SNP Associations with Follicular Lymphoma Risk
Foo JN; Smedby KE; Akers NK; Berglund M; Irwan ID; Jia X; Li Y; Conde L; Darabi H; Bracci PM; Melbye M; Adami H-O; Glimelius B; Khor CC; Hjalgrim H; Padyukov L; Humphreys K; Enblad G; Skibola CF; de Bakker PIW; Liu J
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2013;28(7):589-595
Clinical depression, antidepressant use and risk of future cardiovascular disease
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Article: BREAST CANCER RESEARCH. 2013;15(3):R48
Mammographic density and survival in interval breast cancers
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Mammographic Density Reduction Is a Prognostic Marker of Response to Adjuvant Tamoxifen Therapy in Postmenopausal Patients With Breast Cancer
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Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2013;92(4):489-503
Functional Variants at the 11q13 Risk Locus for Breast Cancer Regulate Cyclin D1 Expression through Long-Range Enhancers
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Article: NATURE GENETICS. 2013;45(4):371-384
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Confirmation of the reduction of hormone replacement therapy-related breast cancer risk for carriers of the HSD17B1_937_G variant
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A genome-wide association study to identify genetic susceptibility loci that modify ductal and lobular postmenopausal breast cancer risk associated with menopausal hormone therapy use: a two-stage design with replication
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Association of CYP2D6 metabolizer status with mammographic density change in response to tamoxifen treatment
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Article: BREAST CANCER RESEARCH. 2013;15(4):R57
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Article: BREAST CANCER RESEARCH. 2013;15(4):R56
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A meta-analysis of genome-wide association studies of follicular lymphoma
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Article: BREAST CANCER RESEARCH. 2012;14(4):R114
High-throughput mammographic-density measurement: a tool for risk prediction of breast cancer
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Article: BREAST CANCER RESEARCH AND TREATMENT. 2012;134(2):859-866
The influence of mammographic density on breast tumor characteristics
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Article: DEVELOPMENTAL PSYCHOLOGY. 2012;48(3):836-843
Dopamine, Working Memory, and Training Induced Plasticity: Implications for Developmental Research
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Article: PLOS ONE. 2012;7(8):e42445
Genetic Variants in ER Cofactor Genes and Endometrial Cancer Risk
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Article: HUMAN MOLECULAR GENETICS. 2011;20(16):3289-3303
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Article: BREAST CANCER RESEARCH AND TREATMENT. 2011;127(2):503-509
Genetic variation in the androgen estrogen conversion pathway in relation to breast cancer prognosticators
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Article: BREAST CANCER RESEARCH. 2011;13(3):R49
Coffee consumption modifies risk of estrogen-receptor negative breast cancer
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Article: DEVELOPMENTAL SCIENCE. 2011;14(3):591-601
Gains in fluid intelligence after training non-verbal reasoning in 4-year-old children: a controlled, randomized study
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Article: BREAST CANCER RESEARCH AND TREATMENT. 2011;126(3):717-727
A combined analysis of genome-wide association studies in breast cancer
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GWAS of Follicular Lymphoma Reveals Allelic Heterogeneity at 6p21.32 and Suggests Shared Genetic Susceptibility with Diffuse Large B-cell Lymphoma
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Article: BREAST CANCER RESEARCH. 2011;13(1):r10
Genetic variation of ESR1 and its co-activator PPARGC1B is synergistic in augmenting the risk of estrogen receptor-positive breast cancer
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Article: HUMAN HEREDITY. 2011;71(1):11-22
Single- and Multi-Locus Association Tests Incorporating Phenotype Heterogeneity
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Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2011;173(1):48-54
Vitamin D Receptor Genotypes, Ultraviolet Radiation Exposure, and Risk of Non-Hodgkin Lymphoma
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Article: BIOLOGICAL PSYCHIATRY. 2010;68(12):1120-1125
The SNAP25 Gene Is Linked to Working Memory Capacity and Maturation of the Posterior Cingulate Cortex During Childhood
Soderqvist S; McNab F; Peyrard-Janvid M; Matsson H; Humphreys K; Kere J; Klingberg T
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2010;18(12):1322-1326
NordicDB: a Nordic pool and portal for genome-wide control data
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Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2010;19(9):2143-2151
Missense Variants in ATM in 26,101 Breast Cancer Cases and 29,842 Controls
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Article: NATURE GENETICS. 2010;42(8):661-664
Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32
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Journal article: THE INTERNATIONAL JOURNAL OF BIOSTATISTICS. 2010;6(1):1-31
A Stochastic EM Type Algorithm for Parameter Estimation in Models with Continuous Outcomes, under Complex Ascertainment
Grünewald M; Humphreys K; Hössjer O
Article: PLOS GENETICS. 2010;6(7):e1001012
Multi-Variant Pathway Association Analysis Reveals the Importance of Genetic Determinants of Estrogen Metabolism in Breast and Endometrial Cancer Susceptibility
Low YL; Li Y; Humphreys K; Thalamuthu A; Li Y; Darabi H; Wedren S; Bonnard C; Czene K; Iles MM; Heikkinen T; Aittomaki K; Blomqvist C; Nevanlinna H; Hall P; Liu ET; Liu J
Journal article: THE INTERNATIONAL JOURNAL OF BIOSTATISTICS. 2010;6(1):1-37
A Principal Stratification Approach to Assess the Differences in Prognosis between Cancers Caused by Hormone Replacement Therapy and by Other Factors
Sjolander A; Vansteelandt S; Humphreys K
Article: CANCER CAUSES AND CONTROL. 2010;21(5):759-769
Genetic variation in chromosomal translocation breakpoint and immune function genes and risk of non-Hodgkin lymphoma
Fernberg P; Chang ET; Duvefelt K; Hjalgrim H; Eloranta S; Sorensen KM; Porwit A; Humphreys K; Melbye M; Smedby KE
Article: INTERNATIONAL JOURNAL OF BIOSTATISTICS. 2010;6(1):Article-23
A Stochastic EM Type Algorithm for Parameter Estimation in Models with Continuous Outcomes, under Complex Ascertainment
Gruenewald M; Humphreys K; Hoessjer O
Article: BREAST CANCER RESEARCH. 2010;12(6):R93
A genome-wide association scan on estrogen receptor-negative breast cancer
Li J; Humphreys K; Darabi H; Rosin G; Hannelius U; Heikkinen T; Aittomaki K; Blomqvist C; Pharoah PDP; Dunning AM; Ahmed S; Hooning MJ; Hollestelle A; Oldenburg RA; Alfredsson L; Palotie A; Peltonen-Palotie L; Irwanto A; Low HQ; Teoh GHK; Thalamuthu A; Kere J; D'Amato M; Easton DF; Nevanlinna H; Liu J; Czene K; Hall P
Article: BREAST CANCER RESEARCH. 2010;12(2):R23
Effects of childhood body size on breast cancer tumour characteristics
Li J; Humphreys K; Eriksson L; Czene K; Liu J; Hall P
Article: BREAST CANCER RESEARCH. 2010;12(2):R19
Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer
Li J; Eriksson L; Humphreys K; Czene K; Liu J; Tamimi RM; Lindstrom S; Hunter DJ; Vachon CM; Couch FJ; Scott CG; Lagiou P; Hall P
Article: DEVELOPMENTAL NEUROPSYCHOLOGY. 2009;35(1):81-95
Measuring Working Memory Capacity With Greater Precision in the Lower Capacity Ranges
Nutley SB; Soderqvist S; Bryde S; Humphreys K; Klingberg T
Journal article: STATISTICAL APPLICATIONS IN GENETICS AND MOLECULAR BIOLOGY. 2009;8(1):1-44
Ancestral Recombination Graphs under Non-Random Ascertainment, with Applications to Gene Mapping
Hössjer O; Hartman L; Humphreys K
Article: BIOMETRICS. 2009;65(2):514-520
Sensitivity Analysis for Principal Stratum Direct Effects, with an Application to a Study of Physical Activity and Coronary Heart Disease
Sjolander A; Humphreys K; Vansteelandt S; Bellocco R; Palmgren J
Article: BRITISH JOURNAL OF CANCER. 2009;100(8):1358-1364
Common genetic variability in ESR1 and EGF in relation to endometrial cancer risk and survival
Einarsdottir K; Darabi H; Czene K; Li Y; Low YL; Li YQ; Bonnard C; Wedren S; Liu ET; Hall P; Liu J; Humphreys K
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2009;17(4):533-536
GENESTAT: an information portal for design and analysis of genetic association studies
Ripatti S; Becker T; Bickeboeller H; Dominicus A; Fischer C; Humphreys K; Jonasdottir G; Moreau Y; Olsson M; Ploner A; Sheehan N; Van Steen K; Baur M; van Duijn C; Palmgren J
Article: COMPUTATIONAL STATISTICS AND DATA ANALYSIS. 2009;53(5):1802-1817
Utilizing identity-by-descent probabilities for genetic fine-mapping in population based samples, via spatial smoothing of haplotype effects
Hartman L; Hossjer O; Humphreys K
Article: DIABETES, OBESITY AND METABOLISM. 2009;11(Suppl 1):17-24
Three microsatellites from the T1DGC MHC data set show highly significant association with type 1 diabetes, independent of the HLA-DRB1, -DQA1 and -DQB1 genes
Eike MC; Humphreys K; Becker T; Olsson M; Lie BA
Article: GENES AND IMMUNITY. 2009;10(1):56-67
Conditional analyses on the T1DGC MHC dataset: novel associations with type 1 diabetes around HLA-G and confirmation of HLA-B
Eike MC; Becker T; Humphreys K; Olsson M; Lie BA
Article: BMC CANCER. 2008;8:322
Estrogen receptor alpha gene polymorphism and endometrial cancer risk - a case-control study
Wedren S; Lovmar L; Humphreys K; Magnusson C; Melhus H; Syvanen A-C; Kindmark A; Landegren U; Fermer ML; Stiger F; Persson I; Baron JA; Weiderpass E
Article: GENETIC EPIDEMIOLOGY. 2008;32(5):425-433
Testing association in the presence of linkage using the GRE and multiple markers
Jonasdottir G; Becker T; Humphreys K; Palmgren J
Article: STATISTICS IN MEDICINE. 2008;27(14):2635-2650
On informative detection bias in screening studies
Sjolander A; Humphreys K; Palmgren J
Article: PLOS GENETICS. 2008;4(4):e1000054
Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics
Garcia-Closas M; Hall P; Nevanlinna H; Pooley K; Morrison J; Richesson DA; Bojesen SE; Nordestgaard BG; Axelsson CK; Arias JI; Milne RL; Ribas G; Gonzalez-Neira A; Benitez J; Zamora P; Brauch H; Justenhoven C; Hamann U; Ko Y-D; Bruening T; Haas S; Doerk T; Schuermann P; Hillemanns P; Bogdanova N; Bremer M; Karstens JH; Fagerholm R; Aaltonen K; Aittomaki K; Von Smitten K; Blomqvist C; Mannermaa A; Uusitupa M; Eskelinen M; Tengstrom M; Kosma V-M; Kataja V; Chenevix-Trench G; Spurdle AB; Beesley J; Chen X; Devilee P; Van Asperen CJ; Jacobi CE; Tollenaar RAEM; Huijts PEA; Klijn JGM; Chang-Claude J; Kropp S; Slanger T; Flesch-Janys D; Mutschelknauss E; Salazar R; Wang-Gohrke S; Couch F; Goode EL; Olson JE; Vachon C; Fredericksen ZS; Giles GG; Baglietto L; Severi G; Hopper JL; English DR; Southey MC; Haiman CA; Henderson BE; Kolonel LN; Le Marchand L; Stram DO; Hunter DJ; Hankinson SE; Cox DG; Tamimi R; Kraft P; Sherman ME; Chanock SJ; Lissowska J; Brinton LA; Peplonska B; Klijn JGM; Hooning MJ; Meijers-Heijboer H; Collee JM; Van den Ouweland A; Uitterlinden AG; Liu J; Lin LY; Yuqing L; Humphreys K; Czene K; Cox A; Balasubramanian SP; Cross SS; Reed MWR; Blows F; Driver K; Dunning A; Tyrer J; Ponder BAJ; Sangrajrang S; Brennan P; Mckay J; Odefrey F; Gabrieau V; Sigurdson A; Doody M; Struewing JP; Alexander B; Easton DF; Pharoah PD
Article: INTERNATIONAL JOURNAL OF OBESITY. 2008;32(3):407-412
Genetic variation of the adenylyl cyclase 3 (AC3) locus and its influence on type 2 diabetes and obesity susceptibility in Swedish men
Nordman S; Abulaiti A; Hilding A; Langberg E-C; Humphreys K; Ostenson C-G; Efendic S; Gu HF
Article: BREAST CANCER RESEARCH. 2008;10(1):r15
ESR1 and EGF genetic variation in relation to breast cancer risk and survival
Einarsdottir K; Darabi H; Li Y; Low YL; Li YQ; Bonnard C; Sjolander A; Czene K; Wedren S; Liu ET; Hall P; Humphreys K; Liu J
Article: ANNALS OF HUMAN GENETICS. 2007;71(Pt 6):815-827
Fine mapping of disease genes using tagging SNPs
Sjolander A; Hossjer O; Hartman LW; Humphreys K
Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2007;16(9):1775-1783
Associations between androgen and vitamin D receptor microsatellites and postmenopausal breast cancer
Wedren S; Magnusson C; Humphreys K; Melhus H; Kindmark A; Stiger F; Branting M; Persson I; Baron J; Weiderpass E
Article: HUMAN MOLECULAR GENETICS. 2007;16(2):154-164
Effect of ATM, CHEK2 and ERBB2 TAGSNPs and haplotypes on endometrial cancer risk
Einarsdottir K; Humphreys K; Bonnard C; Li Y; Li Y; Chia KS; Liu ET; Hall P; Liu J; Wedren S
Article: PHARMACOGENETICS AND GENOMICS. 2006;16(12):881-889
Liver X receptor gene polymorphisms and adipose tissue expression levels in obesity
Dahlman I; Nilsson M; Jiao H; Hoffstedt J; Lindgren CM; Humphreys K; Kere J; Gustafsson J-A; Arner P; Dahlman-Wright K
Article: PLOS MEDICINE. 2006;3(6):e168-903
Linkage disequilibrium mapping of CHEK2:: Common variation and breast cancer risk
Einarsdottir K; Humphreys K; Bonnard C; Palmgren J; Iles MM; Sjolander A; Li Y; Chia KS; Liu ET; Hall P; Liu J; Wedren S
Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2006;15(2):258-265
Variation in DNA repair genes ERCC2, XRCC1, and XRCC3 and risk of follicular lymphoma
Smedby KE; Lindgren CM; Hjalgrim H; Humphreys K; Schöllkopf C; Chang ET; Roos G; Ryder LP; Falk KI; Palmgren J; Kere J; Melbye M; Glimelius B; Adami HO
Article: BREAST CANCER RESEARCH. 2006;8(6):R67
Comprehensive analysis of the ATM, CHEK2 and ERBB2 genes in relation to breast tumour characteristics and survival:: a population-based case-control and follow-up study
Einarsdottir K; Rosenberg LU; Humphreys K; Bonnard C; Palmgren J; Li Y; Li Y; Chia KS; Liu ET; Hall P; Liu J; Wedren S
Article: BREAST CANCER RESEARCH. 2005;7(6):R890-R896
CYP17 gene polymorphism in relation to breast cancer risk:: a case-control study
Einarsdóttir K; Rylander-Rudqvist T; Humphreys K; Ahlberg S; Jonasdottir G; Weiderpass E; Chia KS; Ingelman-Sundberg M; Persson I; Liu JJ; Hall P; Wedrén S
Article: STATISTICS IN MEDICINE. 2004;23(11):1767-1780
Gene expression profiling for prognosis using Cox regression
Pawitan Y; Bjöhle J; Wedren S; Humphreys K; Skoog L; Huang F; Amler L; Shaw P; Hall P; Bergh J
Article: CARCINOGENESIS. 2003;24(9):1533-1539
Cytochrome P4501B1 gene polymorphisms and postmenopausal breast cancer risk
Rylander-Rudqvist T; Wedrén S; Granath F; Humphreys K; Ahlberg S; Weiderpass E; Oscarson M; Ingelman-Sundberg M; Persson I
Article: MULTIVARIATE BEHAVIORAL RESEARCH. 2000;35(1):89-118
Latent Transition Analysis with Covariates, Nonresponse, Summary Statistics and Diagnostics: Modelling Children's Drawing Development.
Humphreys K; Janson H
Article: SOCIOLOGICAL METHODS & RESEARCH. 1998;26(3):269-299
The latent Markov chain with multivariate random effects - An evaluation of instruments measuring labor market status in the British household panel study
Humphreys K
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All other publications

Corrigendum: ESMO OPEN. 2024;9(5):103462
Worse histopathology and prognosis in women with breast cancer diagnosed during the second trimester of pregnancy (vol 9, 102972, 2024)
Gkekos L; Lundberg FE; Humphreys K; Fredriksson I; Johansson ALV
Preprint: MEDRXIV. 2024;MEDRXIV
Familial risk of postpartum psychosis.
Kępińska AP; Robakis TK; Humphreys K; Liu X; Kahn RS; Munk-Olsen T; Bergink V; Mahjani B
Conference publication: ANNALS OF ONCOLOGY. 2022;33:S184
Using breast cancer risk factors of women to estimate incidence of breast cancer in their sisters
Mao X; He W; Eriksson M; Lindstrom L; Holowko N; Lagercrantz SB; Humphreys K; Easton D; Hall PF; Czene K
Preprint: ARXIV. 2021
Approximation Methods for Mixed Models with Probit Link Functions
Christoffersen B; Clements M; Kjellström H; Humphreys K
Preprint: ARXIV. 2021
Asymptotically Exact and Fast Gaussian Copula Models for Imputation of Mixed Data Types
Christoffersen B; Clements M; Humphreys K; Kjellström H
Other: JNCI CANCER SPECTRUM. 2018;2(4):pky071
Adjuvant Therapy and Mammographic Density Changes in Women Wit h Breast Cancer
Eriksson L; He W; Eriksson M; Humphreys K; Bergh J; Hall P; Czene K
Conference publication: CANCER RESEARCH. 2017;77:p2-03-03-p2-03-03
Molecular differences between screen-detected and interval breast cancers are largely explained by PAM50 subtypes
Czene K; Ivansson E; Klevebring D; Tobin NP; Lindstrom LS; Holm J; Prochazka G; Hilliges C; Palmgren J; Tornberg S; Humphreys K; Hartman J; Frisell J; Rantalainen M; Lindberg J; Hall P; Bergh J; Gronberg H; Li J
Review: GYNECOLOGIC ONCOLOGY. 2016;141(2):386-401
No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer
Hollestelle A; van der Baan FH; Berchuck A; Johnatty SE; Aben KK; Agnarsson BA; Aittomaki K; Alducci E; Andrulis IL; Anton-Culver H; Antonenkova NN; Antoniou AC; Apicella C; Arndt V; Arnold N; Arun BK; Arver B; Ashworth A; Baglietto L; Balleine R; Bandera EV; Barrowdale D; Bean YT; Beckmann L; Beckmann MW; Benitez J; Berger A; Berger R; Beuselinck B; Bisogna M; Bjorge L; Blomqvist C; Bogdanova NV; Bojesen A; Bojesen SE; Bolla MK; Bonanni B; Brand JS; Brauch H; Brenner H; Brinton L; Brooks-Wilson A; Bruinsma F; Brunet J; Bruning T; Budzilowska A; Bunker CH; Burwinkel B; Butzow R; Buys SS; Caligo MA; Campbell I; Carter J; Chang-Claude J; Chanock SJ; Claes KBM; Collee JM; Cook LS; Couch FJ; Cox A; Cramer D; Cross SS; Cunningham JM; Cybulski C; Czene K; Damiola F; Dansonka-Mieszkowska A; Darabi H; de la Hoya M; deFazio A; Dennis J; Devilee P; Dicks EM; Diez O; Doherty JA; Domchek SM; Dorfling CM; Dork T; Dos Santos Silva I; du Bois A; Dumont M; Dunning AM; Duran M; Easton DF; Eccles D; Edwards RP; Ehrencrona H; Ejlertsen B; Ekici AB; Ellis SD; Engel C; Eriksson M; Fasching PA; Feliubadalo L; Figueroa J; Flesch-Janys D; Fletcher O; Fontaine A; Fortuzzi S; Fostira F; Fridley BL; Friebel T; Friedman E; Friel G; Frost D; Garber J; Garcia-Closas M; Gayther SA; Gentry-Maharaj A; Gerdes A-M; Giles GG; Glasspool R; Glendon G; Godwin AK; Goodman MT; Gore M; Greene MH; Grip M; Gronwald J; Kaulich DG; Guenel P; Guzman SR; Haeberle L; Haiman CA; Hall P; Halverson SL; Hamann U; Hansen TVO; Harter P; Hartikainen JM; Healey S; Hein A; Heitz F; Henderson BE; Herzog J; Hildebrandt MAT; Bogdan CK; Hogdall E; Hogervorst FBL; Hopper JL; Humphreys K; Huzarski T; Imyanitov EN; Isaacs C; Jakubowska A; Janavicius R; Jaworska K; Jensen A; Jensen UB; Johnson N; Jukkola-Vuorinen A; Kabisch M; Karlan BY; Kataja V; Kauff N; Kelemen LE; Kerin MJ; Kiemeney LA; Kjaer SK; Knight JA; Knol-Bout JP; Konstantopoulou I; Kosma V-M; Krakstad C; Kristensen V; Kuchenbaecker KB; Kupryjanczyk J; Laitman Y; Lambrechts D; Lambrechts S; Larson MC; Lasa A; Laurent-Puig P; Lazaro C; Le ND; Le Marchand L; Leminen A; Lester J; Levine DA; Li J; Liang D; Lindblom A; Lindor N; Lissowska J; Long J; Lu KH; Lubinski J; Lundvall L; Lurie G; Mai PL; Mannermaa A; Margolin S; Mariette F; Marme F; Martens JWM; Massuger LFAG; Maugard C; Mazoyer S; McGuffog L; McGuire V; McLean C; McNeish L; Meindi A; Menegaux F; Menendez P; Menkiszak J; Menon U; Mensenkamp AR; Miller N; Milne RL; Modugno F; Montagna M; Moysich KB; Mueller H; Mulligan AM; Muranen TA; Narod SA; Nathanson KL; Ness RB; Neuhausen SL; Nevanlinna H; Neven P; Nielsen FC; Nielsen SF; Nordestgaard BG; Nussbaum RL; Odunsi K; Offit K; Olah E; Olopade OI; Olson JE; Olson SH; Oosterwijk JC; Orlow I; Orr N; Orsulic S; Osorio A; Ottini L; Paul J; Pearce CL; Pedersen IS; Peissel B; Pejovic T; Pelttari LM; Perkins J; Permuth-Wey J; Peterlongo P; Peto J; Phelan CM; Phillips K-A; Piedmonte M; Pike MC; Platte R; Plisiecka-Halasa J; Poole EM; Poppe B; Pylkas K; Radice P; Ramus SJ; Rebbeck TR; Reed MWR; Rennert G; Risch HA; Robson M; Rodriguez GC; Romero A; Rossing MA; Rothstein JH; Rudolph A; Runnebaum I; Salani R; Salvesen HB; Sawyer EJ; Schildkraut JM; Schmidt MK; Schmutzler RK; Schneeweiss A; Schoemaker MJ; Schrauder MG; Schumacher F; Schwaab I; Scuvera G; Sellers TA; Severi G; Seynaeve CM; Shah M; Shrubsole M; Siddiqui N; Sieh W; Simard J; Singer CF; Sinilnikova OM; Smeets D; Sohn C; Soller M; Song H; Soucy P; Southey MC; Stegmaier C; Stoppa-Lyonnet D; Sucheston L; Swerdlow A; Tangen IL; Tea M-K; Teixeira MR; Terry KL; Terry MB; Thomassen M; Thompson PJ; Tihomirova L; Tischkowitz M; Toland AE; Tollenaar RAEM; Tomlinson I; Torres D; Truong T; Tsimiklis H; Tung N; Tworoger SS; Tyrer JP; Vachon CM; Van 't Veer LJ; van Altena AM; Van Asperen CJ; van den Berg D; van den Ouweland AMW; van Doom HC; Van Nieuwenhuysen E; van Rensburg EJ; Vergote I; Verhoef S; Vierkant RA; Vijai J; Vitonis AF; von Wachenfeldt A; Walsh C; Wang Q; Wang-Gohrke S; Wappenschmidt B; Weischer M; Weitzel JN; Weltens C; Wentzensen N; Whittemore AS; Wilkens LR; Winqvist R; Wu AH; Wu X; Yang HP; Zaffaroni D; Zamora MP; Zheng W; Ziogas A; Chenevix-Trench G; Pharoah PDP; Rookus MA; Hooning MJ; Goode EL
Published conference paper: STATISTICS IN MEDICINE. 2016;35(7):1193-1209
Joint modelling of longitudinal and survival data: incorporating delayed entry and an assessment of model misspecification
Crowther MJ; Andersson TM-L; Lambert PC; Abrams KR; Humphreys K
Editorial comment: OBSTETRICAL AND GYNECOLOGICAL SURVEY. 2015;70(12):758-762
Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair EDITORIAL COMMENT
Day FR; Ruth KS; Thompson DJ; Lunetta KL; Pervjakova N; Chasman DI; Stolk L; Finucane HK; Sulem P; Bulik-Sullivan B; Esko T; Johnson AD; Elks CE; Franceschini N; He C; Altmaier E; Brody JA; Franke LL; Huffman JE; Keller MF; McArdle PF; Nutile T; Porcu E; Robino A; Rose LM; Schick UM; Smith JA; Teumer A; Traglia M; Vuckovic D; Yao J; Zhao W; Albrecht E; Amin N; Corre T; Hottenga J-J; Mangino M; Smith AV; Tanaka T; Abecasis GR; Andrulis IL; Anton-Culver H; Antoniou AC; Arndt V; Arnold AM; Barbieri C; Beckmann MW; Beeghly-Fadiel A; Benitez J; Bernstein L; Bielinski SJ; Blomqvist C; Boerwinkle E; Bogdanova NV; Bojesen SE; Bolla MK; Borresen-Dale A-L; Boutin TS; Brauch H; Brenner H; Bruening T; Burwinkel B; Campbell A; Campbell H; Chanock SJ; Chapman JR; Chen Y-DI; Chenevix-Trench G; Couch FJ; Coviello AD; Cox A; Czene K; Darabi H; De Vivo I; Demerath EW; Dennis J; Devilee P; Doerk T; dos-Santos-Silva I; Dunning AM; Eicher JD; Fasching PA; Faul JD; Figueroa J; Flesch-Janys D; Gandin I; Garcia ME; Garcia-Closas M; Giles GG; Girotto GG; Goldberg MS; Gonzalez-Neira A; Goodarzi MO; Grove ML; Gudbjartsson DF; Guenel P; Guo X; Haiman CA; Hall P; Hamann U; Henderson BE; Hocking LJ; Hofman A; Homuth G; Hooning MJ; Hopper JL; Hu FB; Huang J; Humphreys K; Hunter DJ; Jakubowska A; Jones SE; Kabisch M; Karasik D; Knight JA; Kolcic I; Kooperberg C; Kosma V-M; Kriebel J; Kristensen V; Lambrechts D; Langenberg C; Li J; Li X; Lindstroem S; Liu Y; Luan J; Lubinski J; Maegi R; Mannermaa A; Manz J; Margolin S; Marten J; Martin NG; Masciullo C; Meindl A; Michailidou K; Mihailov E; Milani L; Milne RL; Mueller-Nurasyid M; Nalls M; Neale BM; Nevanlinna H; Neven P; Newman AB; Nordestgaard BG; Olson JE; Padmanabhan S; Peterlongo P; Peters U; Petersmann A; Peto J; Pharoah PDP; Pirastu NN; Pirie A; Pistis G; Polasek O; Porteous D; Psaty BM; Pylkaes K; Radice P; Raffel LJ; Rivadeneira F; Rudan I; Rudolph A; Ruggiero D; Sala CF; Sanna S; Sawyer EJ; Schlessinger D; Schmidt MK; Schmidt F; Schmutzler RK; Schoemaker MJ; Scott RA; Seynaeve CM; Simard J; Sorice R; Southey MC; Stoeckl D; Strauch K; Swerdlow A; Taylor KD; Thorsteinsdottir U; Toland AE; Tomlinson I; Truong T; Tryggvadottir L; Turner ST; Vozzi D; Wang Q; Wellons M; Willemsen G; Wilson JF; Winqvist R; Wolffenbuttel BBHR; Wright AF; Yannoukakos D; Zemunik T; Zheng W; Zygmunt M; Bergmann S; Boomsma DI; Buring JE; Ferrucci L; Montgomery GW; Gudnason V; Spector TD; van Duijn CM; Alizadeh BZ; Ciullo M; Crisponi L; Easton DF; Gasparini PP; Gieger C; Harris TB; Hayward C; Kardia SLR; Kraft P; McKnight B; Metspalu A; Morrison AC; Reiner AP; Ridker PM; Rotter JI; Toniolo D; Uitterlinden AG; Ulivi S; Voelzke H; Wareham NJ; Weir DR; Yerges-Armstrong LM; Price AL; Stefansson K; Visser JA; Ong KK; Chang-Claude J; Murabito JM; Perry JRB; Murray A
Meeting abstract: EUROPEAN JOURNAL OF CANCER. 2015;51:S167-S168
Associations of breast cancer risk prediction tools with tumor characteristics and metastasis: Analysis of polygenic risk score, mammographic density and Tyrer-Cuzick predicted 10-year breast cancer risk
Holm J; Li J; Darabi H; Eklund M; Eriksson M; Humphreys K; Hall P; Czene K
Conference publication: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2013;177:S121
CHANGE OF MAMMOGRAPHIC DENSITY PREDICTS THE RISK OF CONTRALATERAL BREAST CANCER.
Sandberg MEC; Li J; Hall P; Hartman M; dos-Santos-Silva I; Humphreys K; Czene K
Conference publication: GENETIC EPIDEMIOLOGY. 2012;36(2):166
Single- And Multi-Locus Association Tests Incorporating Phenotype Heterogeneity
Darabi H; Humphreys K
Conference publication: EUROPEAN JOURNAL OF CANCER. 2012;48:S78-S79
Mammographic Density, Tumor Characteristics, and Prognosis
Eriksson L; Czene K; Rosenberg L; Humphreys K; Hall P
Letter: BREAST CANCER RESEARCH AND TREATMENT. 2012;131(1):347-350
The postmenopausal hormone replacement therapy-related breast cancer risk is decreased in women carrying the CYP2C19*17 variant
Justenhoven C; Obazee O; Winter S; Couch FJ; Olson JE; Hall P; Hannelius U; Li J; Humphreys K; Severi G; Giles G; Southey M; Baglietto L; Fasching PA; Beckmann MW; Ekici AB; Hamann U; Baisch C; Harth V; Rabstein S; Lotz A; Pesch B; Bruening T; Ko Y-D; Brauch H
Meeting abstract: BREAST. 2011;20:S30
Coffee consumption modifies risk of estrogen-receptor negative breast cancer
Li J; Humphreys K; Czene K; Liu J; Hall P
Conference publication: CANCER RESEARCH. 2009;69(24):818S-819S
CYP11A1 Is a Predictor of Mammographic Breast Density
Li J; Eriksson L; Humphreys K; Czene K; Liu J; Hall P
Conference publication: GENETIC EPIDEMIOLOGY. 2007;31(6):631
Testing association in the presence of linkage - a powerful score for binary traits
Humphreys K; Jonasdottir G; Palmgren J
Conference publication: DIABETOLOGIA. 2006;49:207
Adenylyl cyclase 3 (AC3) and the genetic susceptibility to type 2 diabetes in Swedish Caucasians
Nordman S; Abulaiti A; Humphreys K; Ostenson C-G; Efendic S; Gu HF
Published conference paper: BMC GENETICS. 2005;6(Suppl 1):S92
Analysis of binary traits: testing association in the presence of linkage
Jonasdottir G; Palmgren J; Humphreys K
Published conference paper: BMC GENETICS. 2005;6(Suppl 1):S74
Fine-scale mapping in case-control samples using locus scoring and haplotype-sharing methods
Humphreys K; Iles MM
Published conference paper: DIABETES. 2004;53:S31-S35
Single nucleotide polymorphisms in the proximal promoter region of the adiponectin (APM1) gene are associated with type 2 diabetes in Swedish Caucasians
Gu HF; Abulaiti A; Östenson CG; Humphreys K; Wahlestedt C; Brookes AJ; Efendic S
Review: BREAST CANCER RESEARCH. 2004;6(4):R437-R449
Oestrogen receptor α gene haplotype and postmenopausal breast cancer risk:: a case control study
Wedrén S; Lovmar L; Humphreys K; Magnusson C; Melhus H; Syvänen AC; Kindmark A; Landegren U; Fermér ML; Stiger F; Persson I; Baron J; Weiderpass E
Conference publication: BREAST CANCER RESEARCH AND TREATMENT. 2002;76:S29
Microarray studies on a population based breast cancer cohort - search for gene profiles with prognostic and predictive value.
Bjohle J; Pawitan Y; Skoog L; Shaw P; Amler L; Humphreys K; Huang F; Egyhazi S; Borg AL; Hagerstrom T; Wedren S; Sandelin K; Hall P; Bergh J
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Grants

Tumour Growth and Spread Models for Evaluation of Early Detection Methodologies and Hormone Therapy Effectiveness in Breast Cancer
Swedish Research Council
1 January 2024 - 31 December 2027
Identification of women at increased risk of breast cancer with unfavorable prognosis
Swedish Research Council
1 January 2023 - 31 December 2025
Association between lower urinary tract symptoms and psychiatric comorbidities in children and adolescents
Swedish Research Council
1 January 2022 - 31 December 2024
New statistical models of tumour progression for studying factors of aggressive breast cancer, tumour heterogeneity and personalised screening
Swedish Research Council
1 January 2021 - 31 December 2023
Development and application of statistical methods for register-based research
Swedish Research Council
1 December 2019 - 31 December 2023
Breast cancer screening in Sweden: non-attendance and false-positive results
Swedish Research Council for Health Working Life and Welfare
1 January 2019 - 31 December 2021
Modeling of tumor growth, lymph node spread, presence of metastases and survival in breast cancer patients
Swedish Cancer Society
1 January 2018
Genetic and mammographic determinants of fatal breast cancer
Swedish Research Council
1 January 2018 - 31 December 2021
Modeling of tumor growth, lymph node spread, presence of metastases and survival in breast cancer patients
Swedish Cancer Society
1 January 2017
Statistical approaches for the identification of aggressive breast cancer and assessment of precision screening; modelling of tumour growth, screening sensitivity and patient survival.
Swedish Research Council
1 January 2017 - 31 December 2020
Long-term health outcomes in women diagnosed with breast cancer
Swedish Research Council for Health Working Life and Welfare
1 January 2017 - 31 December 2019
Improvement of prediction of risk for breast cancer by modeling of tumor growth and new measurement methods of mammographic density.
Swedish Cancer Society
1 January 2016
Improvement of prediction of risk for breast cancer by modeling of tumor growth and new measurement methods of mammographic density.
Swedish Cancer Society
1 January 2015
Inherited and Acquired Determinants of Breast Cancer Prognosis
Swedish Research Council
1 January 2015 - 31 December 2018
Improvement of prediction of risk for breast cancer by modeling of tumor growth and new measurement methods of mammographic density.
Swedish Cancer Society
1 January 2014
Statistical modelling of mammographic density, tumour growth and breast cancer
Swedish Research Council
1 January 2012 - 31 December 2015
Comprehensive picture of breast cancer prognosis
Swedish Research Council
1 January 2012 - 31 December 2014
Characterization of genetic population substructure in Sweden - Implications for association studies in Sweden and Norden
Swedish Research Council
1 January 2010 - 31 December 2012
Development of methods for analyzing pathway and genome-wide genetic data for breast cancer.
Swedish Research Council
1 January 2009 - 31 December 2011
Causal inference for observational studies; Modelling genes and lifestyle as predictors for cancer risk and prognosis
Swedish Research Council
1 January 2009 - 31 December 2011

Employments

Professor, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2019-

Degrees and Education

Docent, Karolinska Institutet, 2002

Supervisor

Evripidis Kapanidis, 2023
Ziyan Ma, 2022
Letizia Orsini, 2022
Emilio Ugalde Morales, Molecular epidemiology studies on risk factors for breast cancer and disease aggressiveness, 2015
Fredrik Strand, Determinants of interval cancer and tumor size among breast cancer screening participants, 2014
Johanna Holm, Aggressive breast cancer: epidemiological studies addressing disease heterogeneity, 2012
Linda Abrahamsson, Statistical models of breast cancer tumour progression for mammography screening data, 2012
Hatef Darabi, Genetic association and risk prediction of breast cancer from an epidemiological and biostatistical perspective, 2008
Louise Eriksson, Mammographic density and breast cancer phenotypes, 2007
Gabriel Isheden, Statistical models of breast cancer tumour growth and spread.
Rickard Strandberg, Breast cancer natural history models and risk prediction in mammography screening cohorts
Jingmei Li, Genetic determinants of breast cancer risk
Xinhe Mao, Epidemiological studies on breast cancer risk factors and screening
Kristjana Einarsdottir, Genetic determinants of postmenopausal breast and endometrial cancer

Other expert reviewer/evaluation assignment

Reviewer for international evaluations, Panel member and external reviewer, programme on High-Quality and Reliable Diagnostic, Treatment and Rehabilitation, The Research Council of Norway, 2017-2017

About me

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Employments

Degrees and Education

Supervisor

Other expert reviewer/evaluation assignment

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