Karin Palmblad

Publications
CV
Public outreach and news

Articles

Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2022;111(2):354-362
Population-based study of multisystem inflammatory syndrome associated with COVID-19 found that 36% of children had persistent symptoms
Kahn R; Berg S; Berntson L; Berthold E; Brodin P; Backstrom F; Compagno M; Fasth A; Framme JL; Horne A; Hattting J; Krol P; Kukka AJ; Mossberg M; Mansson B; Nordenhall C; Nordstrom SI; Nystrom FK; Palmblad K; Rasti R; Rudolph A; Rydenman K; Sundberg E; Save-Soderbergh E; Altman M
Article: PEDIATRIC RHEUMATOLOGY. 2021;19(1):173
Immunoprofiling of active and inactive systemic juvenile idiopathic arthritis reveals distinct biomarkers: a single-center study
Qu H; Sundberg E; Aulin C; Neog M; Palmblad K; Horne AC; Granath F; Ek A; Melen E; Olsson M; Harris HE
Article: MOLECULAR MEDICINE. 2021;27(1):48
Therapeutic administration of etoposide coincides with reduced systemic HMGB1 levels in macrophage activation syndrome
Palmblad K; Schierbeck H; Sundberg E; Horne A-C; Harris HE; Henter J-I; Andersson U
Article: ARTHRITIS & RHEUMATOLOGY. 2021;73(2):336-346
Tapering Canakinumab Monotherapy in Patients With Systemic Juvenile Idiopathic Arthritis in Clinical Remission: Results From a Phase IIIb/IV Open-Label, Randomized Study
Quartier P; Alexeeva E; Constantin T; Chasnyk V; Wulffraat N; Palmblad K; Wouters C; Brunner HI; Marzan K; Schneider R; Horneff G; Martini A; Anton J; Wei X; Slade A; Ruperto N; Abrams K
Article: OSTEOARTHRITIS AND CARTILAGE. 2020;28(5):698-707
Early stage blockade of the alarmin HMGB1 reduces cartilage destruction in experimental OA
Aulin C; Lassacher T; Palmblad K; Harris HE
Article: JMIR MHEALTH AND UHEALTH. 2019;7(2):e10401
Empowering Young People Living With Juvenile Idiopathic Arthritis to Better Communicate With Families and Care Teams: Content Analysis of Semistructured Interviews
Grande SW; Longacre MR; Palmblad K; Montan MV; Berquist RP; Hager A; Kotzbauer G
Article: RMD OPEN. 2019;5(2):e001055
Juvenile idiopathic arthritis and risk of cancer before and after the introduction of biological therapies
Horne A; Delcoigne B; Palmblad K; Askling J
Article: OSTEOARTHRITIS AND CARTILAGE. 2017;25(1):157-165
An in vivo cross-linkable hyaluronan gel with inherent anti-inflammatory properties reduces OA cartilage destruction in female mice subjected to cruciate ligament transection
Aulin C; Lundback P; Palmblad K; Klareskog L; Harris HE
Article: HEPATOLOGY. 2016;64(5):1699-1710
A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug-induced liver injury and postinjury inflammation in mice
Lundback P; Lea JD; Sowinska A; Ottosson L; Furst CM; Steen J; Aulin C; Clarke JI; Kipar A; Klevenvall L; Yang H; Palmblad K; Park BK; Tracey KJ; Blom AM; Andersson U; Antoine DJ; Harris HE
Article: PAIN. 2014;155(9):1802-1813
Spinal HMGB1 induces TLR4-mediated long-lasting hypersensitivity and glial activation and regulates pain-like behavior in experimental arthritis
Agalave NM; Larsson M; Abdelmoaty S; Su J; Baharpoor A; Lundback P; Palmblad K; Andersson U; Harris H; Svensson CI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2013;72(8):1390-1399
TLR4 as receptor for HMGB1 induced muscle dysfunction in myositis
Zong M; Bruton JD; Grundtman C; Yang H; Li JH; Alexanderson H; Palmblad K; Andersson U; Harris HE; Lundberg IE; Westerblad H
Article: ARTHRITIS RESEARCH & THERAPY. 2012;14(1):R36
Renal expression and serum levels of high mobility group box 1 protein in lupus nephritis
Zickert A; Palmblad K; Sundelin B; Chavan S; Tracey KJ; Bruchfeld A; Gunnarsson I
Article: HORMONE RESEARCH IN PAEDIATRICS. 2012;77(3):180-187
Pro-Inflammatory Cytokines Produced by Growth Plate Chondrocytes May Act Locally to Modulate Longitudinal Bone Growth
Fernandez-Vojvodich P; Palmblad K; Karimian E; Andersson U; Savendahl L
Article: MOLECULAR MEDICINE. 2011;17(9-10):1039-1044
Monoclonal Anti-HMGB1 (High Mobility Group Box Chromosomal Protein 1) Antibody Protection in Two Experimental Arthritis Models
Schierbeck H; Lundback P; Palmblad K; Klevenvall L; Erlandsson-Harris H; Andersson U; Ottosson L
Article: ARTHRITIS RESEARCH & THERAPY. 2011;13(4):R136
High mobility group box protein 1 in complex with lipopolysaccharide or IL-1 promotes an increased inflammatory phenotype in synovial fibroblasts
Wahamaa H; Schierbeck H; Hreggvidsdottir HS; Palmblad K; Aveberger A-C; Andersson U; Harris HE
Article: MOLECULAR MEDICINE. 2011;17(1-2):29-35
High-Mobility Group Box-1 Protein (HMGB1) Is Increased in Antineutrophilic Cytoplasmatic Antibody (ANCA)-Associated Vasculitis with Renal Manifestations
Bruchfeld A; Wendt M; Bratt J; Qureshi AR; Chavan S; Tracey KJ; Palmblad K; Gunnarsson I
Article: ARTHRITIS & RHEUMATOLOGY. 2010;62(10):2963-2972
Protective Targeting of High Mobility Group Box Chromosomal Protein 1 in a Spontaneous Arthritis Model
Ostberg T; Kawane K; Nagata S; Yang H; Chavan S; Klevenvall L; Bianchi ME; Harris HE; Andersson U; Palmblad K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(26):11942-11947
A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release
Yang H; Hreggvidsdottir HS; Palmblad K; Wang H; Ochani M; Li J; Lu B; Chavan S; Rosas-Ballina M; Al-Abed Y; Akira S; Bierhaus A; Erlandsson-Harris H; Andersson U; Tracey KJ
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2009;86(3):655-662
The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation
Hreggvidsdottir HS; Ostberg T; Wahamaa H; Schierbeck H; Aveberger A-C; Klevenvall L; Palmblad K; Ottosson L; Andersson U; Harris HE
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2009;69(3):188-193
Highly Arthritis-susceptible DA Rats Express IL-1β in Articular Cartilage
Weiss RJ; Harris HE; Palmblad K
Article: IMMUNOBIOLOGY. 2009;214(4):303-309
High mobility group box chromosomal protein 1 acts as a proliferation signal for activated T lymphocytes
Sundberg E; Fasth AER; Palmblad K; Harris HE; Andersson U
Article: GAIT AND POSTURE. 2008;28(2):229-234
Gait pattern in rheumatoid arthritis
Weiss RJ; Wretenberg P; Stark A; Palmblad K; Larsson P; Grondal L; Brostrom E
Article: ARTHRITIS RESEARCH & THERAPY. 2008;10(1):R1
Oxaliplatin retains HMGB1 intranuclearly and ameliorates collagen type II-induced arthritis
Ostberg T; Wahamaa H; Palmblad K; Ito N; Stridh P; Shoshan M; Lotze MT; Harris HE; Andersson U
Article: IMMUNOLOGY. 2007;122(3):430-437
The novel inflammatory cytokine high mobility group box protein 1 (HMGB1) is expressed by human term placenta
Holmlund U; Wahamaa H; Bachmayer N; Bremme K; Sverremark-Ekstrom E; Palmblad K
Article: ARTHRITIS RESEARCH & THERAPY. 2007;9(2):R35
Morphological characterization of intra-articular HMGB1 expression during the course of collagen-induced arthritis
Palmblad K; Sundberg E; Diez M; Soederling R; Aveberger A-C; Andersson U; Harris HE
Article: ANNALS OF THE RHEUMATIC DISEASES. 2006;65(3):335-341
Orthopaedic surgery of the lower limbs in 49 802 rheumatoid arthritis patients: results from the Swedish National Inpatient Registry during 1987 to 2001
Weiss RJ; Stark A; Wick MC; Ehlin A; Palmblad K; Wretenberg P
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2005;62(1):55-62
Morphological characterization of receptor activator of NFκB ligand (RANKL) and IL-1β expression in rodent collagen-induced arthritis
Weiss RJ; Harris HE; Wick MC; Wretenberg P; Stark A; Palmblad K
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(3):494-496
CNI-1493, an inhibitor of proinflammatory cytokines, retards cartilage destruction in rats with collagen induced arthritis
Larsson E; Harris HE; Palmblad K; Månsson B; Saxne T; Klareskog L
Article: ARTHRITIS RESEARCH & THERAPY. 2005;7(3):R458-R467
Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity
Lundberg K; Nijenhuis S; Vossenaar ER; Palmblad K; van Venrooij WJ; Klareskog L; Zendman AJW; Harris HE
Article: ARTHRITIS & RHEUMATOLOGY. 2003;48(7):2052-2058
Successful treatment of collagen-induced arthritis in mice and rats by targeting extracellular high mobility group box chromosomal protein 1 activity
Kokkola R; Li J; Sundberg E; Aveberger AC; Palmblad K; Yang H; Tracey KJ; Andersson U; Harris HE
Article: ARTHRITIS & RHEUMATOLOGY. 2002;46(10):2598-2603
High mobility group box chromosomal protein 1 - A novel proinflammatory mediator in synovitis
Kokkola R; Sundberg E; Ulfgren AK; Palmblad K; Li J; Wang H; Ulloa L; Yang H; Yan XJ; Furie R; Chiorazzi N; Tracey KJ; Andersson U; Harris HE
Article: JOURNAL OF IMMUNOLOGY. 2001;167(11):6453-6461
IFN-αβ-dependent, IFN-γ secretion by bone-marrow-derived macrophages controls an intracellular bacterial infection
Rothfuchs AG; Gigliotti D; Palmblad K; Andersson U; Wigzell H; Rottenberg ME
Article: AMERICAN JOURNAL OF PATHOLOGY. 2001;158(2):491-500
Dynamics of early synovial cytokine expression in rodent collagen-induced arthritis -: A therapeutic study using a macrophage-deactivating compound
Palmblad K; Erlandsson-Harris H; Tracey KJ; Andersson U
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2000;192(4):565-570
High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes
Andersson U; Wang HC; Palmblad K; Aveberger AC; Bloom O; Erlandsson-Harris H; Janson A; Kokkola R; Zhang MH; Yang H; Tracey KJ
Article: BIOTECHNIC AND HISTOCHEMISTRY. 2000;75(3):101-109
Identification of rat IL-1β, IL-2, IFN-γ and TNF-α in activated splenocytes by intracellular immunostaining
Palmblad K; Andersson U
Article: JOURNAL OF INFECTIOUS DISEASES. 1997;176(5):1303-1312
Targeted suppression of cytokine production in monocytes but not in T lymphocytes by a tetravalent guanylhydrazone (CNI-1493)
Bjork L; Tracey KJ; Ulrich P; Bianchi M; Cohen PS; Akerlund K; Fehniger TE; Andersson U; Andersson J
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All other publications

Meeting abstract: PANCREAS. 2006;33(4):497
High mobility group box-1 (HMGB1) augments pancreatic necrosis in taurocholate induced pancreatitis in rats
Segersvärd R; Palmblad K; Tsai J; Capitano A; Andersson U; Permert J
Thesis / dissertation: 2001
Cytokines and cytokine-directed intervention in experimental arthritis
Palmblad, Karin

Employments

Affiliated to Research, Department of Women's and Children's Health, Karolinska Institutet, 2024-2027

Degrees and Education

Doctor Of Philosophy, Department of Women's and Children's Health, Karolinska Institutet, 2001

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