Jonas Spaak
About me
I am a Cardiologist with a keen interest in vascular medicine, integrated
care, cardiorenal syndrome, heart failure, hypertension, arterial stiffness,
vascular function and sympathetic regulation. My background with a PhD in
Physiology and Post-Doc in Cardiovascular Physiology and Cardiology give me a
solid foundation which enriches my current clinical research. My research
focus on disease mechanisms and their management in patients with vascular
disease and concomitant diabetes or impaired kidney function. In 2013 I
started the Heart-Nephrology-Diabetes clinic, an integrated clinic for
patients with concomitant cardiovascular disease, impaired renal function and
diabetes. I am responsible for a regional referral centre for Vascular
Medicine. I am President of the Swedish Society for Hypertension, Stroke and
Vascular Medicine, and engaged in several other organizations. I believe
efforts in this area will have a real impact on the individual patient, which
I find truly inspiring.
- President Swedish Society for Hypertension, Stroke and Vascular Medicine
(www.hypertoni.org/).
- Past President of KIRCNET- Karolinska Respiration and Circulation research
NETwork (researchnetworks.ki.se/converis/area/201).
- Sir Stanley Davidson Lecturer, Royal College of Physicians of Edinburgh,
2016.
- Swedish representative in VAS, Vascular Independent Research and Education
European Organisation.
- Swedish representative in European Union Medical Specialists, div.
Angiology and vascular medicine.
- Member of the departmental Research Board and head of the Clinical Research
Support Center
MD, Karolinska Institutet, 1999
PhD, Karolinska Institutet, 2001
Clinical Research Fellowship (post-doctoral), Mount Sinai Hospital and
University of Toronto, Cardiology, 2001-2004.
Visiting Scientist, Prince of Wales Medical Research Institute, Sydney, 3
months, 2002.
Specialist in Internal Medicine, 2011
Specialist in Cardiology, 2013
Associate Professor in Cardiology, 2016
ESH Hypertension Specialist, 2023
Research
*From vascular dysfunction to integrated complex chronic disease management *
/Part of the Research Group in Vascular Medicine and Hypertension @ KI-DS /
Main supervisor (PhD) for:
Hermine Rietz, MD on “Cardiovascular effects of obstructive sleep apnea”.
Christina Ekenbäck, interventional cardiologist on “Sympathetic and
vascular regulation in myocardial infarction with angiographically normal
coronary arteries”.
Masih Khedri, MD on “Renal dysfunction and long term outcome after
myocardial infarction”.
Gudrun Evén, RN, on "Patients' perception of care and measures of safety in
a multidiciplinary person-centered clinic".
Henrik Hellqvist, cardiologist, ” Arterial stiffness for risk assessment in
cardiovascular disease”.
-Co-supervisor for Helge Brandberg, MD, Muhammad Rafiq, MA. Felicia
Håkansson, MD, Barbara Salzinger, MD and Christina Montgomerie, MD.
Past:
Main supervisor for Nephrologist Josefin Mörtberg and Cardiologist Kristina
Lundwall.
Teaching
500+ hours teaching at the MD program, Karolinska Instiututet.
50+ invited lectures.
Articles
- Article: JOURNAL OF HYPERTENSION. 2024;42(12):2065-2074
- Article: CLINICAL AUTONOMIC RESEARCH. 2024;:1-10
- Article: CKJ: CLINICAL KIDNEY JOURNAL. 2024;17(11):sfae331
- Article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (EJPC). 2024;:zwae313
- Article: INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS. 2024;187:105447
- Article: JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION : JAMIA. 2024;31(7):1529-1539
- Journal article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2024;83(13):2145
- Article: CLINICAL RESEARCH IN CARDIOLOGY. 2024;:1-10
- Article: JOURNAL OF CLINICAL MEDICINE. 2024;13(6):1750
- Article: CKJ: CLINICAL KIDNEY JOURNAL. 2024;17(3):sfae050
- Article: FRONTIERS IN CARDIOVASCULAR MEDICINE. 2024;11:1449168
- Article: FRONTIERS IN CARDIOVASCULAR MEDICINE. 2024;11:1350726
- Journal article: EUROPEAN HEART JOURNAL. 2023;44:ehad655.2955
- Journal article: EUROPEAN HEART JOURNAL. 2023;44:ehad655.1207
- Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023;24(18):14143
- Article: EUROPEAN HEART JOURNAL - QUALITY OF CARE AND CLINICAL OUTCOMES. 2023;9(6):639-644
- Article: ESC HEART FAILURE. 2023;10(4):2395-2405
- Article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 2023;81(6):400-410
- Article: DIAGNOSTICS. 2023;13(6):1179
- Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2023;373:64-71
- Article: KIDNEY DISEASES. 2023;9(1):39-48
- Article: CLINICAL RESEARCH IN CARDIOLOGY. 2023;112(1):68-74
- Article: BLOOD PRESSURE. 2022;31(1):91-99
- Article: HEALTH EXPECTATIONS. 2022;25(6):3053-3061
- Journal article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2022;33(11S):530
- Article: INTERNET INTERVENTIONS. 2022;29:100562
- Journal article: JOURNAL OF HYPERTENSION. 2022;40(Suppl 1):e83
- Article: INTERNATIONAL ANGIOLOGY. 2022;41(3):258-274
- Journal article: EUROPEAN HEART JOURNAL: ACUTE CARDIOVASCULAR CARE. 2022;11(Supplement_1):zuac041.054
- Article: JOURNAL OF INTERNAL MEDICINE. 2022;291(3):327-337
- Journal article: EUROPEAN HEART JOURNAL: ACUTE CARDIOVASCULAR CARE. 2022;11(1):88
- Article: THE LANCET: DIGITAL HEALTH. 2022;4(1):e37-e45
- Article: CLINICAL BIOCHEMISTRY. 2021;98:17-23
- Article: CLINICAL CARDIOLOGY. 2021;44(11):1567-1574
- Journal article: EUROPEAN HEART JOURNAL. 2021;42(Supplement_1):ehab724.1399
- Article: EUROPEAN HEART JOURNAL: ACUTE CARDIOVASCULAR CARE. 2021;10(7):806-812
- Article: JACC CARDIOVASCULAR IMAGING. 2021;14(9):1774-1783
- Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2021;36(Supplement_1):gfab082.0036
- Article: JOURNAL OF MEDICAL INTERNET RESEARCH. 2021;23(4):e25493
- Article: THE LANCET RESPIRATORY MEDICINE. 2021;9(3):275-284
- Article: ESC HEART FAILURE. 2021;8(1):344-355
- Article: PLOS ONE. 2021;16(4):e0249830
- Article: NEW ENGLAND JOURNAL OF MEDICINE. 2020;383(23):2219-2229
- Article: THROMBOSIS AND HAEMOSTASIS. 2020;120(12):1597-1628
- Article: JOURNAL OF INTERNAL MEDICINE. 2020;288(5):581-592
- Article: THE JOURNAL OF CLINICAL HYPERTENSION. 2020;22(10):1780-1788
- Article: JOURNAL OF MEDICAL INTERNET RESEARCH. 2020;22(9):e19066
- Article: CORONARY ARTERY DISEASE. 2020;31(1):49-58
- Article: CIRCULATION: CARDIOVASCULAR QUALITY AND OUTCOMES. 2019;12(9):e005879
- Article: BMC NEPHROLOGY. 2019;20(1):290
- Article: CLINICAL CHEMISTRY. 2019;65(8):1023-1030
- Article: BMJ CASE REPORTS. 2019;12(4):e227885
- Article: AMERICAN JOURNAL OF MEDICINE. 2019;132(3):374-381.e1
- Article: JOURNAL OF MULTIDISCIPLINARY HEALTHCARE. 2019;12:137-148
- Article: JOURNAL OF MULTIDISCIPLINARY HEALTHCARE. 2019;12:1075-1083
- Article: AMERICAN JOURNAL OF NEPHROLOGY. 2019;50(5):345-356
- Article: LAKARTIDNINGEN. 2018;115:FDXZ
- Article: HEART. 2018;104(19):1575-1582
- Article: BMC NEPHROLOGY. 2018;19(1):247
- Article: AMERICAN JOURNAL OF MEDICINE. 2018;131(9):1118-1124
- Article: ACTA CARDIOLOGICA. 2018;73(4):362-369
- Article: JOURNAL OF HYPERTENSION. 2018;36(1):151-158
- Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2017;248:221-226
- Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2017;245:20-26
- Article: JOURNAL OF PROTEOME RESEARCH. 2017;16(9):3242-3254
- Article: BMC NEPHROLOGY. 2017;18(1):161
- Article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (EJPC). 2017;24(7):724-734
- Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2017;6(3):e005165
- Article: BLOOD COAGULATION AND FIBRINOLYSIS. 2016;27(4):401-407
- Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2016;67(14):1687-1697
- Article: EUROPEAN HEART JOURNAL - QUALITY OF CARE AND CLINICAL OUTCOMES. 2016;2(2):91-98
- Article: EUROPEAN JOURNAL OF HEART FAILURE. 2016;18(1):46-53
- Article: AMERICAN JOURNAL OF CARDIOLOGY. 2015;116(6):838-844
- Article: JACC: HEART FAILURE. 2015;3(3):234-242
- Article: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2015;313(7):707-716
- Article: AMERICAN JOURNAL OF NEPHROLOGY. 2015;42(4):265-273
- Article: HYPERTENSION. 2014;63(6):1319-1325
- Article: JOURNAL OF APPLIED PHYSIOLOGY. 2014;116(9):1182-1188
- Article: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2014;311(9):919-928
- Journal article: EUROPEAN HEART JOURNAL. 2013;34(suppl_1):p3986
- Journal article: EUROPEAN HEART JOURNAL. 2013;34(suppl_1):1076
- Article: CHEST. 2012;142(5):1222-1228
- Article: MEDICAL EDUCATION. 2012;46(4):417-425
- Journal article: INTERNATIONAL JOURNAL OF MEDICAL EDUCATION. 2011;2:56-63
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. 2010;298(6):H2226-H2231
- Journal article: AUTONOMIC NEUROSCIENCE: BASIC AND CLINICAL. 2009;149(1-2):73-74
- Article: EXPERIMENTAL BRAIN RESEARCH. 2009;195(2):317-324
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. 2008;294(2):H605-H612
- Article: JOURNAL OF CARDIAC FAILURE. 2007;13(6):470-475
- Article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2006;96(1):37-45
- Article: HYPERTENSION. 2005;46(6):1327-1332
- Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2005;45(12):2008-2011
- Journal article: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2005;37(Supplement):s224
- Journal article: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2005;37(5):s224
- Article: JOURNAL OF APPLIED PHYSIOLOGY. 2005;98(2):648-654
- Article: JOURNAL OF APPLIED PHYSIOLOGY. 2002;92(1):75-83
- Article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2001;85(1-2):49-55
- Article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2000;83(4-5):303-309
- Article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2000;82(5-6):397-406
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1998;275(3):h940-h945
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All other publications
- Corrigendum: JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION : JAMIA. 2025;32(1):261-263
- Review: DIABETES, OBESITY AND METABOLISM. 2024;26(5):1567-1581
- Letter: JACC CARDIOVASCULAR IMAGING. 2023;16(12):1626-1628
- Letter: JOURNAL OF HUMAN HYPERTENSION. 2023;37(6):428-437
- Letter: JACC CARDIOVASCULAR IMAGING. 2023;16(1):128-129
- Conference publication: EUROPEAN HEART JOURNAL. 2022;43:53
- Review: ANTICANCER RESEARCH. 2022;42(7):3261-3274
- Conference publication: JOURNAL OF HYPERTENSION. 2022;40(Suppl 1):e257
- Conference publication: JOURNAL OF HYPERTENSION. 2022;40(Suppl 1):e128
- Conference publication: JOURNAL OF HYPERTENSION. 2022;40(SUPPL 1):E128
- Conference publication: JOURNAL OF HYPERTENSION. 2022;40(SUPPL):E257
- Conference publication: JOURNAL OF HYPERTENSION. 2022;40(SUPPL):E257
- Conference publication: JOURNAL OF HYPERTENSION. 2022;40(SUPPL):E83
- Conference publication: JOURNAL OF HYPERTENSION. 2022;40(SUPPL):E83
- Conference publication: JOURNAL OF HYPERTENSION. 2022;40(SUPPL):E128
- Conference publication: JOURNAL OF SLEEP RESEARCH. 2022;31
- Preprint: SSRN ELECTRONIC JOURNAL. 2022
- Conference publication: EUROPEAN JOURNAL OF HEART FAILURE. 2022;24:172-173
- Conference publication: EUROPEAN HEART JOURNAL. 2021;42:1268
- Conference publication: JOURNAL OF HYPERTENSION. 2021;39:E47
- Conference publication: JOURNAL OF HYPERTENSION. 2021;39:E299
- Conference publication: EUROPEAN HEART JOURNAL. 2021;42:1399
- Conference publication: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2021;36
- Preprint: SSRN ELECTRONIC JOURNAL. 2021
- Conference publication: INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE. 2021;28(SUPPL 1):S96-S97
- Review: LAKARTIDNINGEN. 2020;117:20102
- Conference publication: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2020;35(Supplement_3):gfaa142.p0577
- Conference publication: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2020;35:897
- Conference publication: JOURNAL OF HYPERTENSION. 2019;37:E1
- Letter: JOURNAL OF HYPERTENSION. 2019;37(2):449-451
- Book chapter: ARTIFICIAL INTELLIGENCE IN HEALTH: LECTURE NOTES IN COMPUTER SCIENCE (INCLUDING SUBSERIES LECTURE NOTES IN ARTIFICIAL INTELLIGENCE AND LECTURE NOTES IN BIOINFORMATICS). 2019;p. 228-244
- Conference publication: EUROPEAN HEART JOURNAL. 2018;39(suppl_1):ehy563.p3641
- Conference publication: EUROPACE. 2018;20(suppl_1):i163
- Review: JOURNAL OF HYPERTENSION. 2018;36(2):221-229
- Conference publication: CIRCULATION. 2018;138
- Conference publication: EUROPEAN HEART JOURNAL. 2018;39:756
- Conference publication: EUROPEAN HEART JOURNAL. 2017;38(suppl_1):ehx502.p2066
- Conference publication: EUROPEAN HEART JOURNAL. 2017;38(suppl_1):ehx493.6011
- Conference publication: EUROPEAN HEART JOURNAL. 2017;38(suppl_1):ehx502.p2464
- Editorial comment: JOURNAL OF HYPERTENSION. 2017;35(6):1168-1169
- Conference publication: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2017;32(suppl_3):iii209-iii210
- Review: THE JOURNAL OF THE ROYAL COLLEGE OF PHYSICIANS OF EDINBURGH. 2017;47(1):83-87
- Conference publication: EUROPEAN HEART JOURNAL. 2017;38:419
- Conference publication: EUROPEAN HEART JOURNAL. 2017;38:1263
- Conference publication: EUROPEAN HEART JOURNAL. 2017;38:1063
- Conference publication: EUROPEAN HEART JOURNAL. 2017;38:508
- Conference publication: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2017;32
- Conference publication: KIDNEY INTERNATIONAL REPORTS. 2016;1(4):s14-s15
- Conference publication: JOURNAL OF HYPERTENSION. 2016;34:E96
- Conference publication: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2016;31(suppl_1):i441
- Conference publication: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2016;31:1441
- Conference publication: EUROPEAN HEART JOURNAL. 2016;37:176
- Conference publication: EUROPEAN HEART JOURNAL. 2016;37:1387
- Conference publication: CIRCULATION. 2015;132(suppl_3)
- Editorial comment: JOURNAL OF HUMAN HYPERTENSION. 2015;29(5):281-282
- Book chapter: CARDIO-RENAL CLINICAL CHALLENGES. 2015;p. 209-215
- Conference publication: EUROPEAN HEART JOURNAL. 2015;36:721
- Conference publication: EUROPEAN HEART JOURNAL. 2015;36:491
- Conference publication: EUROPEAN HEART JOURNAL. 2014;35:1035-1036
- Conference publication: EUROPEAN HEART JOURNAL. 2014;35:687
- Conference publication: EUROPEAN HEART JOURNAL. 2014;35:696
- Review: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2013;76(4):560-572
- Meeting abstract: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2013;61(10):E173
- Conference publication: EUROPEAN HEART JOURNAL. 2013;34:718
- Conference publication: EUROPEAN HEART JOURNAL. 2013;34:188
- Conference publication: EUROPEAN HEART JOURNAL. 2012;33:518
- Review: LAKARTIDNINGEN. 2010;107(46):2884-2887
- Conference publication: EUROPEAN HEART JOURNAL. 2007;28:864-865
- Thesis / dissertation: 2001
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Grants
- Swedish Heart-Lung Foundation1 January 2021 - 31 December 2022
- Swedish Heart-Lung Foundation1 January 2021 - 31 December 2023
- VINNOVA15 April 2020 - 31 March 2021
- Swedish Heart-Lung Foundation1 January 2020 - 31 December 2020
- Swedish Heart-Lung Foundation1 January 2020 - 31 December 2020
- Swedish Heart-Lung Foundation1 January 2019 - 31 December 2019
- Neural and humoral cardiovascular control in human hypertension and heart failure.Heart and Stroke Foundation1 July 2001 - 30 June 2002
Employments
- Adjunct Professor, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, 2025-2029
- Affiliated to Research, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, 2023-2026
Degrees and Education
- VAS European Fellowship of Excellence in Angiology/Vascular Medicine, VAS European Independent Foundation in Angiology/Vascular Medicine, 2024
- ESH Hypertension Specialist, European Society of Hypertension, 2023
- Docent, Karolinska Institutet, 2016
- Doctor Of Philosophy, Department of Physiology and Pharmacology, Karolinska Institutet, 2001
- University Medical Degree, Karolinska Institutet, 1999