Johnny Lorentzen

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About me

Best Paper Award. Indoor Air 2014-2016. Lorentzen et al., ´Chloroanisoles
may explain mold odor and represent a major indoor environment problem in
Sweden` (Indoor Air. 2016
26:207-218).
Best Abstract Award. American College of Rheumatology 2006 (Washington DC,
USA).
Lorentzen et al., ´A gene complex encoding C-type lectin-like receptors
associates with arthritis in both rats and humans` (ACR abstract #655).
2009. Associate Professor Medicinsk inflammationsforskning. KI.
1998. PhD. Medicinsk immunologi. KI.

Articles

Article: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2020;17(3):E930-930
Chloroanisoles and Chlorophenols Explain Mold Odor but Their Impact on the Swedish Population Is Attributed to Dampness and Mold
Lorentzen JC; Juran SA; Ernstgard L; Olsson MJ; Johanson G
Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;72(6):967-974
Mold and dampness exposure and allergic outcomes from birth to adolescence: data from the BAMSE cohort
Thacher JD; Gruzieva O; Pershagen G; Melen E; Lorentzen JC; Kull I; Bergstrom A
Article: INDOOR AIR. 2016;26(2):207-218
Chloroanisoles may explain mold odor and represent a major indoor environment problem in Sweden
Lorentzen JC; Juran SA; Nilsson M; Nordin S; Johanson G
Article: INHALATION TOXICOLOGY. 2015;27(14):810-821
Acute effects of acrolein in human volunteers during controlled exposure
Dwivedi AM; Johanson G; Lorentzen JC; Palmberg L; Sjogren B; Ernstgard L
Article: TOXICOLOGY. 2014;326:74-85
Genetic variation influences immune responses in sensitive rats following exposure to TiO₂ nanoparticles
Gustafsson A; Jonasson S; Sandstrom T; Lorentzen JC; Bucht A
Article: JOURNAL OF APPLIED TOXICOLOGY. 2014;34(3):272-280
Strain differences influence timing and magnitude of both acute and late inflammatory reactions after intratracheal instillation of an alkylating agent in rats
Gustafsson A; Svensson-Elfsmark L; Lorentzen JC; Bucht A
Article: HUMAN MUTATION. 2014;35(2):248-256
A 129-kb Deletion on Chromosome 12 Confers Substantial Protection Against Rheumatoid Arthritis, Implicating the Gene SLC2A3
Veal CD; Reekie KE; Lorentzen JC; Gregersen PK; Padyukov L; Brookes AJ
Article: GENES AND IMMUNITY. 2010;11(4):279-293
RGMA and IL21R show association with experimental inflammation and multiple sclerosis
Nohra R; Beyeen AD; Guo JP; Khademi M; Sundqvist E; Hedreul M; Sellebjerg F; Smestad C; Oturai AB; Harbo HF; Wallstrom E; Hillert J; Alfredsson L; Kockum I; Jagodic M; Lorentzen J; Olsson T
Article: GENES AND IMMUNITY. 2010;11(3):239-245
Finemapping of the arthritis QTL Pia7 reveals co-localization with Oia2 and the APLEC locus
Rintisch C; Kelkka T; Norin U; Lorentzen JC; Olofsson P; Holmdahl R
Article: GENES AND IMMUNITY. 2010;11(1):21-36
Multiple loci comprising immune-related genes regulate experimental neuroinflammation
Marta M; Stridh P; Becanovic K; Gillett A; Ockinger J; Lorentzen JC; Jagodic M; Olsson T
Article: ANNALS OF THE RHEUMATIC DISEASES. 2009;68(12):1925-1932
Definition of arthritis candidate risk genes by combining rat linkage-mapping results with human case-control association data
Backdahl L; Guo JP; Jagodic M; Becanovic K; Ding B; Olsson T; Lorentzen JC
Article: GENES AND IMMUNITY. 2009;10(3):227-236
The rat antigen-presenting lectin-like receptor complex influences innate immunity and development of infectious diseases
Guo JP; Verdrengh M; Tarkowski A; Lange S; Jennische E; Lorentzen JC; Harris RA
Article: ANNALS OF THE RHEUMATIC DISEASES. 2008;67(12):1742-1749
Cellular distribution of the C-type II lectin dendritic cell immunoreceptor (DCIR) and its expression in the rheumatic joint: identification of a subpopulation of DCIR plus T cells
Eklow C; Makrygiannakis D; Backdahl L; Padyukov L; Ulfgren A-K; Lorentzen JC; Malmstrom V
Article: GENES AND IMMUNITY. 2008;9(5):412-418
Differential expression of transcripts for the autoimmunity-related human dendritic cell immunoreceptor
Ronninger M; Eklow C; Lorentzen JC; Klareskog L; Padyukov L
Article: ARTHRITIS & RHEUMATOLOGY. 2008;58(5):1343-1353
Profound and paradoxical impact on arthritis and autoimmunity of the rat antigen-presenting lectin-like receptor complex
Guo JP; Backdahl L; Marta M; Mathsson L; Ronnelid J; Lorentzen JC
Article: ARTHRITIS & RHEUMATOLOGY. 2007;56(8):2620-2632
Association of arthritis with a gene complex encoding C-type lectin-like receptors
Lorentzen JC; Flornes L; Eklow C; Backdahl L; Ribbhammar U; Guo JP; Smolnikova M; Dissen E; Seddighzadeh M; Brookes AJ; Alfredsson L; Klareskog L; Padyukov L; Fossum S
Article: JOURNAL OF IMMUNOLOGY. 2005;174(2):918-924
Resolution of a 16.8-mb autoimmunity-regulating rat chromosome 4 region into multiple encephalomyrelitis quantitative trait loci and evidence for epistasis
Jagodic M; Marta M; Becanovic K; Sheng JR; Nohra R; Olsson T; Lorentzen JC
Article: IMMUNOGENETICS. 2004;56(7):506-517
Identification of lectin-like receptors expressed by antigen presenting cells and neutrophils and their mapping to a novel gene complex
Flornes LM; Bryceson YT; Spurkland A; Lorentzen JC; Dissen E; Fossum S
Article: JOURNAL OF IMMUNOLOGY. 2004;173(2):1366-1373
An advanced intercross line resolves Eae18 into two narrow quantitative trait loci syntenic to multiple sclerosis candidate loci
Jagodic M; Becanovic K; Sheng JR; Wu XC; Bäckdahl L; Lorentzen JC; Wallström E; Olsson T
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2004;137(1):59-64
Adjuvant oil induces waves of arthritogenic lymph node cells prior to arthritis onset
Holm BC; Lorentzen JC; Bucht A
Article: ARTHRITIS & RHEUMATOLOGY. 2004;50(1):297-304
Oligodeoxynucleotides containing CpG motifs can induce T cell-dependent arthritis in rats
Svelander L; Harris HE; Lorentzen JC; Trollmo C; Klareskog L; Bucht A
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;106(1):143-148
Induction of IL-4 by platelet-activating factor
Huang YH; SchaferElinder L; Owman H; Lorentzen JC; Ronnelid J; Frostegard J
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;108(3):415-419
Amelioration of collagen II-induced arthritis in rats by the type IV phosphodiesterase inhibitor Rolipram
Nyman U; Mussener A; Larsson E; Lorentzen J; Klareskog L
Article: HUMAN MOLECULAR GENETICS. 2003;12(17):2087-2096
High resolution mapping of an arthritis susceptibility locus on rat chromosome 4, and characterization of regulated phenotypes
Ribbhammar U; Flornes L; Bäckdahl L; Luthman H; Fossum S; Lorentzen JC
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2003;33(7):1907-1916
Paradoxical effects of arthritis-regulating chromosome 4 regions on myelin oligodendrocyte glycoprotein-induced encephalomyelitis in congenic rats
Becanovic K; Bäckdahl L; Wallström E; Aboul-Enein F; Lassmann H; Olsson T; Lorentzen JC
Article: ARTHRITIS & RHEUMATOLOGY. 2003;48(2):551-559
Mapping and functional characterization of rat chromosome 4 regions that regulate arthritis models and phenotypes in congenic strains
Bäckdahl L; Ribbhammar U; Lorentzen JC
Article: RHEUMATOLOGY. 2002;41(9):996-1000
Serum concentrations of cartilage oligomeric matrix protein, fibrinogen and hyaluronan distinguish inflammation and cartilage destruction in experimental arthritis in rats
Larsson E; Harris HE; Lorentzen JC; Larsson A; Månsson B; Klareskog L; Saxne T
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2002;56(3):248-253
Identification of rat quantitative trait loci that regulate LPS-Induced pro-inflammatory cytokine responses
Xu HW; Wallström E; Becanovic K; Dahlman I; Lorentzen JC
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2002;127(3):430-435
The arthritogenic adjuvant squalene does not accumulate in joints, but gives rise to pathogenic cells in both draining and non-draining lymph nodes
Holm BC; Svelander L; Bucht A; Lorentzen JC
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;120(3):532-536
CD8⁺ cells suppress oil-induced arthritis
Jansson Å; Lorentzen JC; Bucht A
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2001;54(6):599-605
Responses of the rat immune system to arthritogenic adjuvant oil
Svelander L; Holm BC; Bucht A; Lorentzen JC
Article: HUMAN MOLECULAR GENETICS. 2001;10(18):1901-1906
High resolution linkage and association mapping identifies a novel rheumatoid arthritis susceptibility locus homologous to one linked to two rat models of inflammatory arthritis
Barton A; Eyre S; Myerscough A; Brintnell B; Ward D; Ollier WER; Lorentzen JC; Klareskog L; Silman A; John S
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2001;9(6):458-463
Linkage analysis in multiple sclerosis of chromosomal regions syntenic to experimental autoimmune disease loci
Xu C; Dai YM; Lorentzen JC; Dahlman I; Olsson T; Hillert J
Article: HUMAN MOLECULAR GENETICS. 2001;10(6):565-572
Rats made congenic for Oia3 on chromosome 10 become susceptible to squalene-induced arthritis
Holm BC; Xu HW; Jacobsson L; Larsson A; Luthman H; Lorentzen JC
Article: JOURNAL OF NEUROENDOCRINOLOGY. 2000;12(11):1096-1104
Analysis of adrenocortical secretory responses during acute and prolonged immune stimulation in inflammation-susceptible and -resistant rat strains
Andersson IM; Lorentzen JC; Ericsson-Dahlstrand A
Article: AMERICAN JOURNAL OF PATHOLOGY. 2000;156(6):2057-2065
The endogenous adjuvant squalene can induce a chronic T-cell-mediated arthritis in rats
Carlson BC; Jansson Å; Larsson A; Bucht A; Lorentzen JC
Article: JOURNAL OF NEUROIMMUNOLOGY. 1999;101(1):87-97
Non-MHC gene regulation of nerve root injury induced spinal cord inflammation and neuron death
Piehl F; Lundberg C; Khademi M; Bucht A; Dahlman I; Lorentzen JC; Olsson T
Article: JOURNAL OF IMMUNOLOGY. 1999;162(5):2581-2588
Genome-wide linkage analysis of chronic relapsing experimental autoimmune encephalomyelitis in the rat identifies a major susceptibility locus on chromosome 9
Dahlman I; Jacobsson L; Glaser A; Lorentzen JC; Andersson M; Luthman H; Olsson T
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1999;49(1):45-50
Identification of arthritogenic adjuvants of self and foreign origin
Lorentzen JC
Article: JOURNAL OF CLINICAL INVESTIGATION. 1998;102(6):1265-1273
MHC haplotype-dependent regulation of MOG-induced EAE in rats
Weissert R; Wallström E; Storch MK; Stefferl A; Lorentzen J; Lassmann H; Linington C; Olsson T
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1998;28(7):2188-2196
Quantitative trait loci disposing for both experimental arthritis and encephalomyelitis in the DA rat; impact on severity of myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis and antibody isotype pattern
Dahlman I; Lorentzen JC; de Graaf KL; Stefferl A; Linington C; Luthman H; Olsson T
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1998;95(11):6383-6387
Identification of rat susceptibility loci for adjuvant-oil-induced arthritis
Lorentzen JC; Glaser A; Jacobsson L; Galli J; Fakhrai-Rad H; Klareskog L; Luthman H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1997;46(6):619-624
Immunization with alum-collagen II complex suppresses the development of collagen-induced arthritis in rats by deviating the immune response
Mattsson L; Lorentzen JC; Svelander L; Bucht A; Nyman U; Klareskog L; Larsson P
Article: JOURNAL OF NEUROIMMUNOLOGY. 1997;80(1-2):31-37
Genetic analysis of inflammation, cytokine mRNA expression and disease course of relapsing experimental autoimmune encephalomyelitis in DA rats
Lorentzen JC; Andersson M; Issazadeh S; Dahlman I; Luthman H; Weissert R; Olsson T
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1997;27(3):695-699
Altered Th1/Th2 balance associated with nonmajor histocompatibility complex genes in collagen-induced arthritis in resistant and nonresistant rat strains
Mussener A; Lorentzen JC; Kleinau S; Klareskog L
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1996;44(6):592-598
Susceptibility of DA rats to arthritis induced with adjuvant oil or rat collagen is determined by genes both within and outside the major histocompatibility complex
Lorentzen JC; Klareskog L
Article: JOURNAL OF NEUROIMMUNOLOGY. 1996;69(1-2):103-115
Cytokines in relapsing experimental autoimmune encephalomyelitis in DA rats: Persistent mRNA expression of proinflammatory cytokines and absent expression of interleukin-10 and transforming growth factor-beta
Issazadeh S; Lorentzen JC; Mustafa MI; Hojeberg B; Mussener A; Olsson T
Article: JOURNAL OF NEUROIMMUNOLOGY. 1995;63(2):193-205
Protracted, relapsing and demyelinating experimental autoimmune encephalomyelitis in DA rats immunized with syngeneic spinal cord and incomplete Freund's adjuvant
Lorentzen JC; Issazadeh S; Storch M; Mustafa MI; Lassman H; Linington C; Klareskog L; Olsson T
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1995;42(1):128-134
TNF-ALPHA DOMINATES CYTOKINE MESSENGER-RNA EXPRESSION IN LYMPHOID-TISSUES OF RATS DEVELOPING COLLAGEN-INDUCED AND OIL-INDUCED ARTHRITIS
MUSSENER A; KLARESKOG L; LORENTZEN JC; KLEINAU S
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1995;42(1):82-89
SPECIFIC AND LONG-LASTING PROTECTION FROM COLLAGEN-INDUCED ARTHRITIS AND OIL-INDUCED ARTHRITIS IN DA RATS BY ADMINISTRATION OF IMMUNOGENS
LORENTZEN JC; ERLANDSSON H; MUSSENER A; MATTSSON L; KLEINAU S; NYMAN U; KLARESKOG L
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All other publications

Review: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2022;19(23):15542
Overcrowding and Hazardous Dwelling Condition Characteristics: A Systematic Search and Scoping Review of Relevance for Health
Lorentzen JC; Johanson G; Bjork F; Stensson S
Review: NATURE CLINICAL PRACTICE RHEUMATOLOGY. 2006;2(8):425-433
Mechanisms of disease: genetic susceptibility and environmental triggers in the development of rheumatoid arthritis
Klareskog L; Padyukov L; Lorentzen J; Alfredsson L
Review: ARTHRITIS RESEARCH & THERAPY. 2002;4(Suppl 3):S31-S36
Genes and environment in arthritis: can RA be prevented?
Klareskog L; Lorentzen J; Padyukov L; Alfredsson L
Review: IMMUNOLOGICAL REVIEWS. 2001;184:184-202
Arthritis induced in rats with non-immunogenic adjuvants as models for rheumatoid arthritis
Holmdahl R; Lorentzen JC; Lu SM; Olofsson P; Wester L; Holmberg J; Pettersson U
Published conference paper: TRANSPLANTATION PROCEEDINGS. 1999;31(3):1597-1599
Susceptibility to oil-induced arthritis is linked to Oia2 on chromosome 4 in a DA(DA x PVG.1AV1) backcross
Jansson Å; Jacobsson L; Luthman H; Lorentzen JC
Published conference paper: TRANSPLANTATION PROCEEDINGS. 1999;31(3):1594-1596
Susceptibility of rats to homologous collagen-induced arthritis depends on MHC genes in the class II region
Mattsson L; Klareskog L; Lorentzen JC
Thesis / dissertation: 1998
Pathogenesis of arthritis in rats : genetic factors and inducing molecules
Lorentzen, Johnny C
Published conference paper: TRANSPLANTATION PROCEEDINGS. 1997;29(3):1692-1693
Comparative susceptibility of DA, LEW, and LEW.1AV1 rats to arthritis induced with different arthritogens: Mineral oil, mycobacteria, muramyl dipeptide, avridine and rat collagen type II
Lorentzen JC; Klareskog L
Published conference paper: TRANSPLANTATION PROCEEDINGS. 1997;29(3):1686-1689
Major histocompatibility complex haplotype RT1(av1) is associated with relapsing/remitting experimental autoimmune encephalomyelitis
Wallstrom E; Weissert R; Lorentzen J; Olsson T
Published conference paper: TRANSPLANTATION PROCEEDINGS. 1995;27(2):1532-1534
SUSCEPTIBILITY TO OIL-INDUCED ARTHRITIS IN THE DA RAT IS DETERMINED BY MHC AND NON-MHC GENES
LORENTZEN JC; OLSSON T; KLARESKOG L
Published conference paper: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, SUPPLEMENT. 1995;101:179-181
ROLE OF ADJUVANTS IN TURNING AUTOIMMUNITY INTO AUTOIMMUNE-DISEASE
KLEINAU S; LORENTZEN J; KLARESKOG L

Employments

Affiliated to Research, Institute of Environmental Medicine, Karolinska Institutet, 2022-2025

Degrees and Education

Docent, Karolinska institutet, 2009

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