Johan Fastbom

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About me

Johan Fastbom was appoined Professor of Geriatric Pharmacology at Karolinska Institutet in 2011. His research is about improving the quality of drug use in elderly people.

Articles

Journal article: DRUGS AND AGING. 2024;41(9):775-781
Trends in Drug Duplications in Swedish Older Adults: A Nationwide Register Study from 2006 to 2021
Erhan T; Wastesson JW; Fastbom J
Article: EUROPEAN HEART JOURNAL. 2023;44(7):573-582
Cardiometabolic multimorbidity and incident dementia: the Swedish twin registry
Dove A; Guo J; Marseglia A; Fastbom J; Vetrano DL; Fratiglioni L; Pedersen NL; Xu W
Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2023;51(1):11-20
Socio-demographic differences in polypharmacy and potentially inappropriate drug use among older people with different care needs and in care settings in Stockholm, Sweden
Doheny M; Schon P; Orsini N; Fastbom J; Burstrom B; Agerholm J
Article: FRONTIERS IN PHARMACOLOGY. 2023;14:1030849
Regional variations in excessive polypharmacy and potentially inappropriate drug use among older adults in Sweden: Trends from 2006 to 2020
Wastesson JW; Fritzell J; Burstrom B; Johnell K; Fastbom J
Article: JAMA NETWORK OPEN. 2022;5(10):e2236757
Performance of 3 Sets of Criteria for Potentially Inappropriate Prescribing in Older People to Identify Inadequate Drug Treatment
Wallerstedt SM; Svensson SA; Lonnbro J; Hieronymus F; Fastbom J; Hoffmann M; Lopez NP
Article: ORAL DISEASES. 2022;28(6):1697-1704
Validating a model for medication-related dental outcomes in older people
Tan ECK; Lexomboon D; Habel H; Fastbom J; Eriksdotter M; Johnell K; Sandborgh-Englund G
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2022;78(9):1459-1467
Prevalence and initiation of statin therapy in the oldest old-a longitudinal population-based study
Sundvall H; Vitols S; Wallerstedt SM; Fastbom J
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2022;37(3):10.1002/gps.5684
Psychoactive medication use and risk of suicide in long-term care facility residents
Hedna K; Fastbom J; Jonson M; Wilhelmson K; Waern M
Article: PRIMARY HEALTH CARE RESEARCH AND DEVELOPMENT. 2021;22:e45
District nurses' experiences of using a clinical decision support system and an assessment tool at elderly care units in primary health care: a qualitative study
Lagerin A; Tornkvist L; Fastbom J; Lundh L
Article: FRONTIERS IN PUBLIC HEALTH. 2021;9:611559
Antidepressant Use and Suicide Rates in Adults Aged 75 and Above: A Swedish Nationwide Cohort Study
Hedna K; Fastbom J; Erlangsen A; Waern M
Article: THE JOURNALS OF GERONTOLOGY. SERIES A, BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2020;75(12):2441-2449
Predictors of Olfactory Decline in Aging: A Longitudinal Population-Based Study
Ekstrom I; Larsson M; Rizzuto D; Fastbom J; Backman L; Laukka EJ
Article: SCANDINAVIAN JOURNAL OF WORK, ENVIRONMENT & HEALTH. 2020;46(6):589-598
Psychosocial job strain and polypharmacy: a national cohort study
Tan ECK; Pan K-Y; Hanson LLM; Fastbom J; Westerlund H; Wang H-X
Article: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2020;30(5):958-964
Sociodemographic and gender determinants of late-life suicide in users and non-users of antidepressants
Hedna K; Hensing G; Skoog I; Fastbom J; Waern M
Article: BMC PUBLIC HEALTH. 2020;20(1):764
What are the sociodemographic and gender determinants of non-fatal self-harm in older adult users and non-users of antidepressants? A national population-based study
Hedna K; Fastbom J; Skoog I; Hensing G; Waern M
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2020;75(4):1263-1271
Xerogenic Medications as a Predictor for Dental Health Intervention in People with Dementia
Tan ECK; Lexomboon D; Habel H; Fastbom J; Eriksdotter M; Johnell K; Sandborgh-Englund G
Article: PRIMARY HEALTH CARE RESEARCH AND DEVELOPMENT. 2020;21:e15
District nurses' use of a decision support and assessment tool to improve the quality and safety of medication use in older adults: a feasibility study
Lagerin A; Lundh L; Tornkvist L; Fastbom J
Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2020;48(3):308-315
Extent and quality of drug use in community-dwelling people aged ≥75 years: A Swedish nationwide register-based study
Lagerin A; Tornkvist L; Nilsson G; Johnell K; Fastbom J
Article: BMJ OPEN. 2020;10(3):e034560
Drug use and torsades de pointes cardiac arrhythmias in Sweden: a nationwide register-based cohort study.
Danielsson B; Collin J; Nyman A; Bergendal A; Borg N; State M; Bergfeldt L; Fastbom J
Article: BMC GERIATRICS. 2020;20(1):73
Use of potentially inappropriate medication and polypharmacy in older adults: a repeated cross-sectional study
Thorell K; Midlov P; Fastbom J; Halling A
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2020;73(3):1013-1021
Secondary Stroke Prevention After Ischemic Stroke in Patients with Alzheimer's Disease and Other Dementia Disorders
Zupanic E; Kramberger MG; Von Euler M; Norrving B; Winblad B; Secnik J; Fastbom J; Eriksdotter M; Garcia-Ptacek S
Article: BMJ OPEN DIABETES RESEARCH & CARE. 2020;8(1):e000833
Cholinesterase inhibitors in patients with diabetes mellitus and dementia: an open-cohort study of ∼23 000 patients from the Swedish Dementia Registry
Secnik J; Schwertner E; Alvarsson M; Hammar N; Fastbom J; Winblad B; Garcia-Ptacek S; Religa D; Eriksdotter M
Article: ARCHIVES OF GERONTOLOGY AND GERIATRICS. 2020;86:103960
Factors associated with emergency department revisits among older adults in two Swedish regions: A prospective cohort study
Naseer M; Agerholm J; Fastbom J; Schon P; Ehrenberg A; Dahlberg L
Article: AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY. 2020;28(1):108-117
Do Acetylcholinesterase Inhibitors Prevent or Delay Psychotropic Prescribing in People With Dementia? Analyses of the Swedish Dementia Registry
Tan ECK; Johnell K; Bell JS; Garcia-Ptacek S; Fastbom J; Nordstrom P; Eriksdotter M
Article: BMJ OPEN. 2019;9(9):e029477
Importance of potentially inappropriate medications, number of chronic conditions and medications for the risk of hospitalisation in elderly in Sweden: a case-control study.
Thorell K; Midlöv P; Fastbom J; Halling A
Article: PALLIATIVE MEDICINE. 2019;33(8):1080-1090
How many older adults receive drugs of questionable clinical benefit near the end of life? A cohort study
Morin L; Wastesson JW; Laroche M-L; Fastbom J; Johnell K
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2019;75(7):959-967
Use of statins in the elderly according to age and indicationa cross-sectional population-based register study
Sundvall H; Fastbom J; Wallerstedt SM; Vitols S
Article: CANCER. 2019;125(13):2309-2317
Preventive drugs in the last year of life of older adults with cancer: Is there room for deprescribing?
Morin L; Todd A; Barclay S; Wastesson JW; Fastbom J; Johnell K
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2018;19(12):1080-1085.e2
The Effect of Xerostomic Medication on Oral Health in Persons With Dementia
Lexomboon D; Tan ECK; Hoijer J; Garcia-Ptacek S; Eriksdotter M; Religa D; Fastbom J; Johnell K; Sandborgh-Englund G
Article: NEUROLOGY. 2018;91(19):e1732-e1740
Atrial fibrillation, antithrombotic treatment, and cognitive aging A population-based study
Ding M; Fratiglioni L; Johnell K; Santoni G; Fastbom J; Ljungman P; Marengoni A; Qiu C
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2018;74(10):1333-1342
Adequate, questionable, and inadequate drug prescribing for older adults at the end of life: a European expert consensus
Morin L; Laroche M-L; Vetrano DL; Fastbom J; Johnell K
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2018;65(2):589-596
Anticholinergic Burden and Risk of Stroke and Death in People with Different Types of Dementia.
Tan ECK; Eriksdotter M; Garcia-Ptacek S; Fastbom J; Johnell K
Article: ALZHEIMER'S AND DEMENTIA. 2018;14(7):944-951
Acetylcholinesterase inhibitors and risk of stroke and death in people with dementia
Tan ECK; Johnell K; Garcia-Ptacek S; Haaksma ML; Fastbom J; Bell JS; Eriksdotter M
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2018;19(7):577-583
Antihypertensive Medication Regimen Intensity and Incident Dementia in an Older Population
Tan ECK; Qiu C; Liang Y; Wang R; Bell JS; Fastbom J; Fratiglioni L; Johnell K
Article: DRUGS AND AGING. 2018;35(3):243-248
Prescription Changes During Geriatric Care Episodes: A Trend Analysis Conducted in Sweden
Reimers M; Eriksdotter M; Seiger A; Fastbom J
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2018;19(3):193-199
Research Priorities for Optimizing Geriatric Pharmacotherapy: An International Consensus
Tan ECK; Sluggett JK; Johnell K; Onder G; Elseviers M; Morin L; Vetrano DL; Wastesson JW; Fastbom J; Taipale H; Tanskanen A; Bell JS
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2018;61(3):1119-1128
Treatment of Atrial Fibrillation in Patients with Dementia: A Cohort Study from the Swedish Dementia Registry
Subic A; Cermakova P; Religa D; Han S; von Euler M; Kareholt I; Johnell K; Fastbom J; Bognandi L; Winblad B; Kramberger MG; Eriksdotter M; Garcia-Ptacek S
Article: CLINICAL EPIDEMIOLOGY. 2018;10:289-298
The epidemiology of polypharmacy in older adults: register-based prospective cohort study
Morin L; Johnell K; Laroche M-L; Fastbom J; Wastesson JW
Article: PLOS ONE. 2018;13(3):e0194892
The composition of polypharmacy: A register-based study of Swedes aged 75 years and older
Wastesson JW; Minguez AC; Fastbom J; Maioli S; Johnell K
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2017;249:173-178
Atrial fibrillation and use of antithrombotic medications in older people: A population-based study
Ding M; Fratiglioni L; Johnell K; Fastbom J; Ljungdahl M; Qiu C
Article: NEUROLOGY. 2017;89(18):1860-1868
Thrombolysis in acute ischemic stroke in patients with dementia A Swedish registry study
Zupanic E; von Euler M; Kareholt I; Escamez BC; Fastbom J; Norrving B; Religa D; Kramberger MG; Winblad B; Johnell K; Eriksdotter M; Garcia-Ptacek S
Article: DIABETES CARE. 2017;40(9):1159-1166
Diabetes in a Large Dementia Cohort: Clinical Characteristics and Treatment From the Swedish Dementia Registry
Secnik J; Cermakova P; Fereshtehnejad S-M; Dannberg P; Johnell K; Fastbom J; Winblad B; Eriksdotter M; Religa D
Article: AMERICAN JOURNAL OF MEDICINE. 2017;130(8):927-936.e9
Choosing Wisely? Measuring the Burden of Medications in Older Adults near the End of Life: Nationwide, Longitudinal Cohort Study
Morin L; Vetrano DL; Rizzuto D; Calderon-Larranaga A; Fastbom J; Johnell K
Article: SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE. 2017;35(3):271-278
Pay for performance associated with increased volume of medication reviews but not with less inappropriate use of medications among the elderly - an observational study
Odesjo H; Anell A; Boman A; Fastbom J; Franzen S; Thorn J; Bjorck S
Article: DRUGS AND AGING. 2017;34(7):529-533
Drug Use in Older Adults with Amyotrophic Lateral Sclerosis Near the End of Life
Grande G; Morin L; Vetrano DL; Fastbom J; Johnell K
Article: NEUROBIOLOGY OF AGING. 2017;55:27-32
Anticholinergic drug use is associated with episodic memory decline in older adults without dementia
Papenberg G; Backman L; Fratiglioni L; Laukka EJ; Fastbom J; Johnell K
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2017;58(4):1265-1272
Living Alone with Alzheimer's Disease: Data from SveDem, the Swedish Dementia Registry
Cermakova P; Nelson M; Secnik J; Garcia-Ptacek S; Johnell K; Fastbom J; Kilander L; Winblad B; Eriksdotter M; Religa D
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2017;32(6):675-684
Cognitive performance in unipolar old-age depression: a longitudinal study
Pantzar A; Atti AR; Fratiglioni L; Fastbom J; Backman L; Laukka EJ
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2017;18(6):551.e1-551.e7
Use of Medications of Questionable Benefit During the Last Year of Life of Older Adults With Dementia
Morin L; Vetrano DL; Grande G; Fratiglioni L; Fastbom J; Johnell K
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2017;32(4):414-420
Psychotropic drugs and the risk of fall injuries, hospitalisations and mortality among older adults
Johnell K; Bergman GJ; Fastbom J; Danielsson B; Borg N; Salmi P
Article: JOURNAL OF NURSING MANAGEMENT. 2017;25(1):56-64
Nurses' use of computerised decision support systems affects drug monitoring in nursing homes
Johansson-Pajala R-M; Gustafsson L-K; Blomgren KJ; Fastbom J; Martin L
Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2017;26(1):9-16
Long-term use of proton pump inhibitors and prevalence of disease-and drug-related reasons for gastroprotection-a cross-sectional population-based study
Wallerstedt SM; Fastbom J; Linke J; Vitols S
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2017;18(1):19-23
Management of Acute Myocardial Infarction in Patients With Dementia: Data From SveDem, the Swedish Dementia Registry
Cermakova P; Szummer K; Johnell K; Fastbom J; Winblad B; Eriksdotter M; Religa D
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2016;134(5):430-440
Antidepressants and mortality risk in a dementia cohort: data from SveDem, the Swedish Dementia Registry
Enache D; Fereshtehnejad S-M; Kareholt I; Cermakova P; Garcia-Ptacek S; Johnell K; Religa D; Jelic V; Winblad B; Ballard C; Aarsland D; Fastbom J; Eriksdotter M
Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2016;64(9):1851-1857
Aggressiveness of End-of-Life Care for Hospitalized Individuals with Cancer with and without Dementia: A Nationwide Matched-Cohort Study in France
Morin L; Beaussant Y; Aubry R; Fastbom J; Johnell K
Article: EUROPEAN JOURNAL OF INTERNAL MEDICINE. 2016;31:29-34
Coexisting chronic conditions in the older population: Variation by health indicators
Marengoni A; Angleman S; Meinow B; Santoni G; Mangialasche F; Rizzuto D; Fastbom J; Melis R; Parker M; Johnell K; Fratiglioni L
Article: PARKINSONISM AND RELATED DISORDERS. 2016;27:85-88
Use of antidepressants in Parkinson's disease: A Swedish register-based study of over 1.5 million older people
Haasum Y; Fastbom J; Johnell K
Article: THE JOURNALS OF GERONTOLOGY. SERIES A, BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2016;71(6):831-837
Medication Regimen Complexity and Number of Medications as Factors Associated With Unplanned Hospitalizations in Older People: A Population-based Cohort Study
Wimmer BC; Bell JS; Fastbom J; Wiese MD; Johnell K
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2016;81(4):773-783
Antidepressants and antipsychotics classified with torsades de pointes arrhythmia risk and mortality in older adults - a Swedish nationwide study
Danielsson B; Collin J; Bergman GJ; Borg N; Salmi P; Fastbom J
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2016;52(1):213-222
Influence of Incipient Dementia on Hospitalization for Primary Care Sensitive Conditions: A Population-Based Cohort Study
Pimouguet C; Rizzuto D; Fastbom J; Lagergren M; Fratiglioni L; Xu W
Article: ARCHIVES OF GERONTOLOGY AND GERIATRICS. 2016;63:28-35
Time trends in 20 years of medication use in older adults: Findings from three elderly cohorts in Stockholm, Sweden
Craftman AG; Johnell K; Fastbom J; Westerbotn M; von Strauss E
Article: BMC NEUROLOGY. 2016;16:28
The impact of dementia on drug costs in older people: results from the SNAC study
Skoldunger A; Fastbom J; Wimo A; Fratiglioni L; Johnell K
Article: THE JOURNALS OF GERONTOLOGY. SERIES A, BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2016;71(2):188-195
Telomerase Gene (hTERT) and Survival: Results From Two Swedish Cohorts of Older Adults
Kalpouzos G; Rizzuto D; Keller L; Fastbom J; Santoni G; Angleman S; Graff C; Backman L; Fratiglioni L
Article: ANNALS OF PHARMACOTHERAPY. 2016;50(2):89-95
Medication Regimen Complexity and Polypharmacy as Factors Associated With All-Cause Mortality in Older People: A Population-Based Cohort Study
Wimmer BC; Bell JS; Fastbom J; Wiese MD; Johnell K
Article: ALZHEIMER'S AND DEMENTIA. 2016;12(2):100-109
Prudent diet may attenuate the adverse effects of Western diet on cognitive decline
Shakersain B; Santoni G; Larsson SC; Faxen-Irving G; Fastbom J; Fratiglioni L; Xu W
Article: SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE. 2016;34(1):37-45
Nurses in municipal care of the elderly act as pharmacovigilant intermediaries: a qualitative study of medication management
Johansson-Pajala R-M; Blomgren KJ; Bastholm-Rahmner P; Fastbom J; Martin L
Article: PLOS ONE. 2016;11(8):e0161246
Use of Fall-Risk Inducing Drugs in Patients Using Anti-Parkinson Drugs (APD): A Swedish Register-Based Study
Haasum Y; Fastbom J; Johnell K
Article: THE BRITISH JOURNAL OF PSYCHIATRY. SUPPLEMENT. 2015;207(5):444-449
Incidence of antipsychotic use in relation to diagnosis of Alzheimer's disease among community-dwelling persons
Koponen M; Tolppanen A-M; Taipale H; Tanskanen A; Tiihonen J; Johnell K; Fastbom J; Ahonen R; Hartikainen S
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2015;48(4):949-958
Cardiovascular Diseases in ∼30,000 Patients in the Swedish Dementia Registry
Cermakova P; Johnell K; Fastbom J; Garcia-Ptacek S; Lund LH; Winblad B; Eriksdotter M; Religa D
Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2015;24(9):906-914
Association between drug-specific indicators of prescribing quality and quality of drug treatment: a validation study
Wallerstedt SM; Belfrage B; Fastbom J
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2015;71(9):1099-1108
Factors associated with medication regimen complexity in older people: a cross-sectional population-based study
Wimmer BC; Johnell K; Fastbom J; Wiese MD; Bell JS
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2015;80(2):315-324
Potentially inappropriate drug use in older people: a nationwide comparison of different explicit criteria for population-based estimates
Morin L; Fastbom J; Laroche M-L; Johnell K
Article: DRUGS AND AGING. 2015;32(8):671-678
Impact of Inappropriate Drug Use on Hospitalizations, Mortality, and Costs in Older Persons and Persons with Dementia: Findings from the SNAC Study
Skoldunger A; Fastbom J; Wimo A; Fratiglioni L; Johnell K
Article: JOURNAL OF EVALUATION IN CLINICAL PRACTICE. 2015;21(1):145-152
Nurses' self-reported medication competence in relation to their pharmacovigilant activities in clinical practice
Johansson-Pajala R-M; Martin L; Fastbom J; Blomgren KJ
Article: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2014;24(6):991-996
Socioeconomic inequalities in access to specialized psychotropic prescribing among older Swedes: a register-based study
Wastesson JW; Fastbom J; Weitoft GR; Fors S; Johnell K
Article: PSYCHOLOGICAL MEDICINE. 2014;44(5):937-947
Cognitive deficits in unipolar old-age depression: a population-based study
Pantzar A; Laukka EJ; Atti AR; Fastbom J; Fratiglioni L; Backman L
Article: DRUGS AND AGING. 2014;31(3):225-232
Prevalence and Impact of Fall-Risk-Increasing Drugs, Polypharmacy, and Drug-Drug Interactions in Robust Versus Frail Hospitalised Falls Patients: A Prospective Cohort Study
Bennett A; Gnjidic D; Gillett M; Carroll P; Matthews S; Johnell K; Fastbom J; Hilmer S
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2013;69(3):665-671
Different patterns in use of antibiotics for lower urinary tract infection in institutionalized and home-dwelling elderly: a register-based study
Haasum Y; Fastbom J; Johnell K
Article: PLOS ONE. 2013;8(6):e67088
Drug Treatment in Older People before and after the Transition to a Multi-Dose Drug Dispensing System-A Longitudinal Analysis
Wallerstedt SM; Fastbom J; Johnell K; Sjoberg C; Landahl S; Sundstrom A
Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2012;40(9 Suppl):293-304
Prescription drugs: Health in Sweden: The National Public Health Report 2012. Chapter 18.
Weitoft GR; Ericsson O; Fastbom J
Article: DRUGS AND AGING. 2012;29(9):751-758
Comparison of Prescription Drug Use between Community-Dwelling and Institutionalized Elderly in Sweden
Johnell K; Fastbom J
Article: ANNALS OF PHARMACOTHERAPY. 2012;46(3):339-346
Institutionalization as a Risk Factor for Inappropriate Drug Use in the Elderly: A Swedish Nationwide Register-Based Study
Haasum Y; Fastbom J; Johnell K
Article: AGE AND AGEING. 2012;41(2):218-224
Drug use in centenarians compared with nonagenarians and octogenarians in Sweden: a nationwide register-based study
Wastesson JW; Parker MG; Fastbom J; Thorslund M; Johnell K
Article: OSTEOPOROSIS INTERNATIONAL. 2012;23(3):1061-1068
Undertreatment of osteoporosis in persons with dementia? A population-based study
Haasum Y; Fastbom J; Fratiglioni L; Johnell K
Article: INTERNATIONAL JOURNAL OF CLINICAL PHARMACY. 2011;33(5):788-793
Gender and use of hypnotics or sedatives in old age: a nationwide register-based study
Johnell K; Fastbom J
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2011;67(10):1069-1075
Antiepileptic drug use in community-dwelling and institutionalized elderly: a nationwide study of over 1 300 000 older people
Johnell K; Fastbom J
Article: SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE. 2011;29(3):181-186
Dementia management programme in a community setting and the use of psychotropic drugs in the elderly population
Jedenius E; Johnell K; Fastbom J; Stromqvist J; Winblad B; Andreasen N
Article: DRUGS AND AGING. 2011;28(4):283-293
Pain Treatment in Elderly Persons With and Without Dementia A Population-Based Study of Institutionalized and Home-Dwelling Elderly
Haasum Y; Fastbom J; Fratiglioni L; Kareholt I; Johnell K
Article: PLOS ONE. 2011;6(10):e26574
Association between Multi-Dose Drug Dispensing and Quality of Drug Treatment - A Register-Based Study
Sjoberg C; Edward C; Fastbom J; Johnell K; Landahl S; Narbro K; Wallerstedt SM
Article: INTERNATIONAL JOURNAL OF HEALTH CARE QUALITY ASSURANCE. 2010;23(6):571-582
Medication reviews with computerised expert support: evaluation of a method to improve the quality of drug utilisation in the elderly.
Ulfvarson J; Rahmner PB; Fastbom J; Sjöviker S; Karlsson EA
Article: CLINICAL DRUG INVESTIGATION. 2010;30(5):289-300
Quality of Drug Prescribing in Elderly People in Nursing Homes and Special Care Units for Dementia
Olsson J; Bergman A; Carlsten A; Oke T; Bernsten C; Schmidt IK; Fastbom J
Article: ARCHIVES OF OSTEOPOROSIS. 2009;4(1-2):17-23
Undertreatment of osteoporosis in the oldest old? A nationwide study of over 700,000 older people.
Johnell K; Fastbom J
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2009;24(7):731-738
The use of benzodiazpines and related drugs amongst older people in Sweden: Associated factors and concomitant use of other psychotropics
Johnell K; Fastbom J
Article: ANNALS OF PHARMACOTHERAPY. 2009;43(7-8):1233-1238
Sex Differences in Inappropriate Drug Use: a Register-Based Study of Over 600,000 Older People
Johnell K; Weitoft GR; Fastborn J
Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2009;57(1):62-69
The Influence of Educational Level on Polypharmacy and Inappropriate Drug Use: A Register-Based Study of More Than 600,000 Older People
Haider SI; Johnell K; Weitoft GR; Thorslund M; Fastbom J
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2008;64(12):1215-1222
Patient educational level and use of newly marketed drugs: a register-based study of over 600,000 older people
Haider SI; Johnell K; Weitoft GR; Thorslund M; Fastbom J
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2008;64(11):1119-1124
The association between use of cardiovascular drugs and antidepressants: a nationwide register-based study
Johnell K; Fastbom J
Article: JOURNAL OF CLINICAL NURSING (JCN). 2008;17(5A):106-115
How do older people experience their management of medicines?
Westerbotn M; Fahlstrom E; Fastbom J; Aguero-Torres H; Hilleras P
Article: AGING CLINICAL AND EXPERIMENTAL RESEARCH. 2008;20(1):40-46
Pain reporting by very old Swedish community dwellers:: the role of cognition and function
Westerbotn M; Hilleras P; Fastbom J; Aguero-Torres H
Article: CLINICAL THERAPEUTICS. 2008;30(2):419-427
Analysis of the association between polypharmacy and socioeconomic position among elderly aged 77 years in Sweden
Haider SI; Johnell K; Thorslund M; Fastbom J
Article: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. 2008;25(1):54-59
Education and use of dementia drugs: A register-based study of over 600,000 older people
Johnell K; Weitoft GR; Fastbom J
Article: SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE. 2008;26(2):86-91
Multi-dose drug dispensing and inappropriate drug use: A nationwide register-based study of over 700000 elderly
Johnell K; Fastbom J
Article: CLINICAL DRUG INVESTIGATION. 2008;28(11):687-695
Concomitant Use of Gastroprotective Drugs among Elderly NSAID/COX-2 Selective Inhibitor Users A Nationwide Register-Based Study
Johnell K; Fastbom J
Article: DRUGS AND AGING. 2008;25(10):871-877
Concurrent Use of Anticholinergic Drugs and Cholinesterase Inhibitors Register-Based Study of Over 700 000 Elderly Patients
Johnell K; Fastbom J
Article: INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2007;45(12):643-653
Trends in polypharmacy and potential drug-drug interactions across educational groups in elderly patients in Sweden for the period 1992-2002
Haider SI; Johnell K; Thorslund M; Fastbom J
Article: ANNALS OF PHARMACOTHERAPY. 2007;41(7-8):1243-1248
Inappropriate drug use in the elderly:: a nationwide register-based study
Johnell K; Fastbom J; Rosen M; Leimanis A
Article: SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE. 2007;25(1):9-14
Evaluation of the quality of drug therapy among elderly patients in nursing homes -: A computerized pharmacy register analysis
Bergman A; Olsson J; Carlsten A; Waern M; Fastbom J
Article: AGING CLINICAL AND EXPERIMENTAL RESEARCH. 2006;18(6):497-502
Factors influencing the handling of medicines among very old people living at home in an urban area
Westerbotn M; Hilleras P; Fastbom J; Aguero-Torres H
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2006;62(7):555-562
The use of angiotensin-converting enzyme inhibitors and other drugs with cardiovascular effects by non-demented and demented elderly with a clinical diagnosis of heart failure. A population-based study of the very old
Klarin I; Fastbom J; Wimo A
Article: ARCHIVES OF INTERNAL MEDICINE (CHICAGO, ILL. : 1908). 2006;166(9):1003-1008
Heart failure and risk of dementia and Alzheimer disease - A population-based cohort study
Qiu C; Winblad B; Marengoni A; Klarin I; Fastbom J; Fratiglioni L
Article: PHARMACY WORLD AND SCIENCE. 2005;27(5):393-398
The difficulty of opening medicine containers in old age: A population-based study
Beckman A; Bernsten C; Parker MG; Thorslund M; Fastbom J
Article: ARCHIVES OF GERONTOLOGY AND GERIATRICS. 2005;40(3):287-297
A population-based study on well-being in the very old:: the role of cardiovascular diseases and drugs
Westerbotn M; Agüero-Torres H; Fastbom J; Hillerås P
Article: DRUGS AND AGING. 2005;22(1):69-82
The association of inappropriate drug use with hospitalisation and mortality - A population-based study of the very old
Klarin I; Wimo A; Fastbom J
Article: LAKARTIDNINGEN. 2004;101(46):3683-3688
[Shortages in the treatment of depression of the elderly in nursing homes in Stockholm. Diagnosis is based on flimsy ground, follow up performed early].
Fastbom J; Schmidt I
Article: NEUROEPIDEMIOLOGY. 2004;23(3):135-143
Aspirin, NSAIDs, risk of dementia, and influence of the apolipoprotein E epsilon 4 allele in an elderly population
Cornelius C; Fastbom J; Winblad B; Viitanen M
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2004;60(2):121-126
Drug use and increased HbA1c levels in non-diabetic very elderly persons:: the Kungsholmen project
Passare G; Fastbom J; Törring O; Viitanen M
Article: CLINICAL DRUG INVESTIGATION. 2004;24(9):535-544
Sodium and potassium disturbances in the elderly -: Prevalence and association with drug use
Passare G; Viitanen M; Törring O; Winblad B; Fastbom J
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2004;8(1):127-134
β-secretase-cleaved amyloid precursor protein in Alzheimer brain:: a morphologic study
Sennvik K; Bogdanovic N; Volkmann I; Fastbom J; Benedikz E
Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2003;12(8):669-678
A population-based study of drug use in the very old living in a rural district of Sweden, with focus on cardiovascular drug consumption: comparison with an urban cohort
Klarin I; Fastbom J; Wimo A
Article: NEUROLOGY. 2003;61(5):655-660
Combined effects of APOE genotype, blood pressure, and antihypertensive drug use on incident AD
Qiu CX; Winblad B; Fastbom J; Fratiglioni L
Article: NEUROREPORT. 2003;14(11):1523-1527
G-protein α-subunit levels in hippocampus and entorhinal cortex of brains staged for Alzheimer's disease neurofibrillary and amyloid pathologies
García-Jiménez A; Fastbom J; Ohm TG; Cowburn RF
Article: ARCHIVES OF NEUROLOGY. 2003;60(2):223-228
Low blood pressure and risk of dementia in the Kungsholmen project - A 6-year follow-up study
Qiu CX; von Strauss E; Fastbom J; Winblad B; Fratiglioni L
Article: ANNALS OF PHARMACOTHERAPY. 2002;36(11):1675-1681
Drug-drug interactions in the elderly.
Björkman IK; Fastbom J; Schmidt IK; Bernsten CB; Pharmaceutical Care of the Elderly in Europe Resea
Article: ARCHIVES OF GERONTOLOGY AND GERIATRICS. 2002;35(2):95-105
Cognitive functioning in a population-based sample of very old non-demented and non-depressed persons:: the impact of diabetes
Nilsson E; Fastbom J; Wahlin Å
Article: NEUROPSYCHOLOGY. 2002;16(2):208-216
Cognitive performance in very old diabetic persons:: The impact of semantic structure, preclinical dementia, and impending death
Wahlin Å; Nilsson E; Fastbom J
Article: THE JOURNALS OF GERONTOLOGY. SERIES A, BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2002;57(4):M236-M240
Sleep problems in a very old population: Drug use and clinical correlates
Giron MST; Forsell Y; Bernsten C; Thorslund M; Winblad B; Fastbom J
Article: JOURNAL OF NEUROSCIENCE RESEARCH. 2002;67(3):388-398
Loss of stimulatory effect of guanosine triphosphate on [³⁵S]GTPγS binding correlates with Alzheimer's disease neurofibrillary pathology in entorhinal cortex and CA1 hippocampal subfield
García-Jiménez A; Cowburn RF; Ohm TG; Lasn H; Winblad B; Bogdanovic N; Fastbom A
Article: BLOOD PRESSURE. 2002;11(1):46-52
The potential economic consequences of cognitive improvement with losartan
Jönsson L; Gerth W; Fastbom J
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2001;3(6):585-591
Blood pressure and dementia in persons 75+years old: 3-year follow-up results from the Kungsholmen Project
Guo Z; Qiu C; Viitanen M; Fastbom J; Winblad B; Fratiglioni L
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2001;16(9):900-906
Psychotropic drug use in elderly people with and without dementia
Giron MST; Forsell Y; Bernsten C; Thorslund M; Winblad B; Fastbom J
Article: NEUROLOGY. 2001;56(9):1188-1194
Vitamin B₁₂ and folate in relation to the development of Alzheimer's disease
Wang HX; Wahlin A; Basun H; Fastbom J; Winblad B; Fratiglioni L
Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2001;49(3):277-283
The appropriateness of drug use in an older nondemented and demented population
Giron MST; Wang HX; Bernsten C; Thorslund M; Winblad B; Fastbom J
Article: JOURNAL OF NEUROSCIENCE RESEARCH. 2001;63(5):429-437
Calcium ionophore A23187 specifically decreases the secretion of β-secretase cleaved amyloid precursor protein during apoptosis in primary rat cortical cultures
Sennvik K; Benedikz E; Fastbom J; Sundström E; Winblad B; Ankarcrona M
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2001;153(3):225-231
Apolipoprotein E genotypes and the incidence of Alzheimer's disease among persons aged 75 years and older: Variation by use of antihypertensive medication?
Guo ZC; Fratiglioni L; Viitanen M; Lannfelt L; Basun H; Fastbom J; Winblad B
Article: CLINICAL DRUG INVESTIGATION. 2000;20(6):433-446
Quality of drug use in Swedish nursing homes - A follow-up study
Schmidt IK; Fastbom J
Article: JOURNALS OF GERONTOLOGY - SERIES B PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES. 2000;55(5):P259-P265
The relationship between signs of cardiovascular deficiency and cognitive performance in old age:: A population-based study
Fahlander K; Wahlin Å; Fastbom J; Grut M; Forsell Y; Hill RD; Winblad B; Bäckman L
Article: THE JOURNALS OF GERONTOLOGY. SERIES A, BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2000;55(6):M322-M328
Mild cognitive impairment in the population and physical health: Data on 1,435 individuals aged 75 to 95
Frisoni GB; Fratiglioni L; Fastbom J; Guo ZC; Viiranen M; Winblad B
Article: NEUROSCIENCE LETTERS. 2000;278(3):169-172
Levels of α- and β-secretase cleaved amyloid precursor protein in the cerebrospinal fluid of Alzheimer's disease patients
Sennvik K; Fastbom J; Blomberg M; Wahlund LO; Winblad B; Benedikz E
Article: BRAIN RESEARCH. 1999;850(1-2):104-117
Quantitative autoradiography of [³H]forskolin binding sites in post-mortem brain staged for Alzheimer's disease neurofibrillary changes and amyloid deposits
García-Jiménez A; Cowburn RF; Ohm TG; Bogdanovic N; Winblad B; Fastbom J
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 1999;150(10):1031-1044
Mortality in nondemented subjects with cognitive impairment: The influence of health-related factors
Frisoni GB; Fratiglioni L; Fastbom J; Viitanen M; Winblad B
Article: NEUROREPORT. 1999;10(11):2423-2427
Inhibition of [³H]forskolin binding by Gpp[NH]p may reflect adenylate cyclase coupling to G_i
Garcia-Jiménez A; Cowburn RF; Winblad B; Fastbom J
Article: ARCHIVES OF NEUROLOGY. 1999;56(8):991-996
Occurrence and progression of dementia in a community population aged 75 years and older -: Relationship of antihypertensive medication use
Guo ZC; Fratiglioni L; Zhu L; Fastbom J; Winbald B; Viitanen M
Article: ARCHIVES OF GERONTOLOGY AND GERIATRICS. 1999;29(1):29-43
Musculoskeletal pain and analgesic therapy in a very old population
Grimby C; Fastbom J; Forsell Y; Thorslund M; Claesson CB; Winblad B
Article: BRAIN RESEARCH. 1999;818(2):383-396
A quantitative autoradiographic study of [³H]cAMP binding to cytosolic and particulate protein kinase A in post-mortem brain staged for Alzheimer's disease neurofibrillary changes and amyloid deposits
Bonkale WL; Cowburn RF; Ohm TG; Bogdanovic N; Fastbom J
Article: NEUROSCIENCE. 1999;92(2):499-513
Alterations in the ryanodine receptor calcium release channel correlate with Alzheimer's disease neurofibrillary and β-amyloid pathologies
Kelliher M; Fastbom J; Cowburn RF; Bonkale W; Ohm TG; Ravid R; Sorrentino V; O'Neill C
Article: CLINICAL DRUG INVESTIGATION. 1999;17(5):389-398
Drug use patterns in a very elderly population - A seven-year review
Giron MST; Claesson C; Thorslund M; Oke T; Winblad B; Fastbom J
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 1998;148(9):887-892
Cognitive impairment, drug use, and the risk of hip fracture in persons over 75 years old: A community-based prospective study
Guo ZC; Wills P; Viitanen M; Fastbom J; Winblad B
Article: NEUROREPORT. 1998;9(14):3329-3333
Inhibition of [³H]forskolin binding by Gpp[NH]p may reflect adenylyl cyclase coupling to G_i
García-Jiménez A; Cowburn RF; Einblad B; Fastbom J
Article: BRAIN RESEARCH. 1998;796(1-2):209-221
Loss of inositol 1,4,5-trisphosphate receptor sites and decreased PKC levels correlate with staging of Alzheimer's disease neurofibrillary pathology
Kurumatani T; Fastbom J; Bonkale WL; Bogdanovic N; Winblad B; Ohm TG; Cowburn RF
Article: ALZHEIMER DISEASE AND ASSOCIATED DISORDERS. 1998;12(1):14-17
Benzodiazepines may have protective effects against Alzheimer disease
Fastbom J; Forsell Y; Winblad B
Article: CLINICAL DRUG INVESTIGATION. 1998;15(6):497-506
Drug use and low blood pressure in the elderly - A study of data from the Kungsholmen Project
Passare G; Guo ZC; Winblad B; Fastbom J
Article: AGE AND AGEING. 1997;26(5):383-391
Drug use by demented and non-demented elderly people
Wills P; Claesson CB; Fratiglioni L; Fastbom J; Thorslund M
Article: NEUROCHEMICAL RESEARCH. 1997;22(8):1055-1063
Autoradiographic characterisation of [S-35]GTP gamma S binding sites in rat brain
GarciaJimenez A; Cowburn RF; Winblad B; Fastbom J
Article: BRAIN RESEARCH. 1997;763(1):1-13
Autoradiographic characterization of [H-3]cGMP binding sites in the rat brain
Bonkale WL; Cowburn RF; Winblad B; Fastbom J
Article: JOURNAL OF NEURAL TRANSMISSION. 1997;104(2-3):175-189
Autoradiographic characterization of [H-3]inositol(1,4,5)trisphosphate and [H-3]inositol(1,3,4,5)tetrakisphosphate binding sites in human brain
Kurumatani T; Cowburn RF; Bogdanovic N; Winblad B; Fastbom J
Article: CLINICAL DRUG INVESTIGATION. 1997;13(2):105-117
Self-reported symptoms in the elderly - Prevalence and association with drug use
Cornelius C; Fastbom J; Claesson CB; Wills P; Thorslund M; Viitanen M; Winblad B
Article: BRAIN RESEARCH. 1996;737(1-2):155-161
Impaired G-protein-stimulated adenylyl cyclase activity in Alzheimer's disease brain is not accompanied by reduced cyclic-AMP-dependent protein kinase A activity
Bonkale WL; Fastbom J; Wiehager B; Ravid R; Winblad B; Cowburn RF
Article: ARCHIVES OF GERONTOLOGY AND GERIATRICS. 1996;23(2):179-188
Levels of serum creatinine and estimated creatinine clearance over the age of 75: A study of an elderly Swedish population
Fastbom J; Wills P; Cornelius C; Viitanen M; Winblad B
Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 1996;44(1):54-60
Use of cardiovascular drugs in an older Swedish population
Wills P; Fastbom J; Claesson CB; Cornelius C; Thorslund M; Winblad B
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Review: HEALTHCARE TECHNOLOGY LETTERS. 2023;10(3):62-72
Feasibility study of a clinical decision support system for polymedicated patients in primary care
Manzanet JMP; Fico G; Merino-Barbancho B; Hernandez L; Vera-Munoz C; Seara G; Torrego M; Gonzalez H; Wastesson J; Fastbom J; Mayol J; Johnell K; Gomez-Gascon T; Arredondo MT
Review: BMC GERIATRICS. 2023;23(1):155
Few geriatric heart failure patients investigated according to clinical guidelines: a retrospective review of patient records
Wessberg MR; Seiger A; Fastbom J; Eriksdotter M
Letter: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2016;17(10):957-958
Expanding the Proportion of Life With Polypharmacy in Sweden: 2006-2013
Wastesson JW; Fastbom J; Johnell K
Letter: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2016;64(9):1927-1928
DEPRESCRIBING STATINS-IS IT ETHICAL? RESPONSE
Gnjidic D; Fastbom J; Johnell K
Letter: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2016;64(1):223-224
STATIN THERAPY AND DEMENTIA IN OLDER ADULTS: ROLE OF DISEASE SEVERITY AND MULTIMORBIDITY
Gnjidic D; Fastbom J; Fratiglioni L; Rizzuto D; Angleman S; Johnell K
Review: DRUGS AND AGING. 2015;32(3):189-199
National Indicators for Quality of Drug Therapy in Older Persons: the Swedish Experience from the First 10 Years
Fastbom J; Johnell K
Review: LAKARTIDNINGEN. 2006;103(6):369-371
[Administration of symptom-relieving drugs in Alzheimer disease is beneficial].
Nordberg A; Eriksdotter-Jönhagen M; Garlind A; Grut M; Freund-Levi Y; Cornelius C; Ekström A; Fastbom J; Sedvall M; Viitanen M
Review: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2005;20(3):201-217
Clinical trials of potential antidepressants: to what extent are the elderly represented: a review
Giron MST; Fastbom J; Winblad B
Meeting abstract: NEUROBIOLOGY OF AGING. 2004;25:S53
Heart failure and risk of dementia in the kungsholmen project: A six-year follow-up study
Qiu CX; Winblad B; Marengoni A; Fastbom J; Fratiglioni L
Letter: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2002;50(3):590-591
Are the unsafe combinations always inappropriate? In Reply
Giron MST; Wang HX; Winbald B; Fastbom J; Bernstein C; Thorslund M
Review: LAKARTIDNINGEN. 2001;98(14):1674-1679
[Increased consumption of drugs among the elderly results in greater risk of problems].
Fastbom J
Published conference paper: BIOCHEMICAL SOCIETY SYMPOSIUM. 2001;67(67):177-194
Dysfunctional intracellular calcium homoeostasis: a central cause of neurodegeneration in Alzheimer's disease
O'Neill C; Cowburn RF; Bonkale WL; Ohm TG; Fastbom J; Carmody M; Kelliher M
Published conference paper: BIOCHEMICAL SOCIETY SYMPOSIUM. 2001;67(67):163-175
Receptor-G-protein signalling in Alzheimer's disease
Cowburn RF; O'Neill C; Bonkale WL; Ohm TG; Fastbom J
Other: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 1995;43(10):1135-1140
THE USE OF MEDICINES WITH ANTICHOLINERGIC EFFECTS IN OLDER-PEOPLE - A POPULATION STUDY IN AN URBAN AREA OF SWEDEN
FASTBOM J; CLAESSON CB; CORNELIUS C; THORSLUND M; WINBLAD B

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Professor, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2011-

Degrees and Education

Docent, Karolinska Institutet, 1998

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