Johan Engdahl

Johan Engdahl

Professor/Senior Consultant
Mobile phone: 073-7593374
Visiting address: Entrévägen 2, 18257 Danderyd
Postal address: D1 Kliniska vetenskaper, Danderyds sjukhus, D1 Kardiologi Arytmi, 171 77 Stockholm
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About me

  • I hold a position as a professor of Cardiology at the Department of Clinical Sciences, Karolinska Institutet, and as a senior consultant, Department of Cardiology at  the same hospital. Our research group is dedicated to improve detection, monitoring and treatment in patients with atrial fibrillation, partly by studying ECG screening and alternative ways of detecting patients with atrial fibrillation. 

Research

  • The majority of our projects are clinical trials, many of them with hard clinical endpoints. One of the landmark studies on atrial fibrillation screening, STROKESTOP (NCT01593553), was performed by our group. The biomarker-enhanced STROKESTOP II (NCT02743416) will report the primary endpoint during 2024. A randomised clinical trial on AF detection post stroke (AF SPICE, NCT05134454) is recruiting from 30 stroke units in Sweden and will report its primary endpoint in 2028. Further projects include developement and implementation of smartphone PPG heart rhythm diagnosis (SMARTBEATS, NCT04300270), digital, siteless and risk prediction model-enhanced atrial fibrillation screening in high-risk groups (CONSIDERING-AF, NCT05838781), the relation between excessive supraventricular activity and atrial fibrillation (ESA AF, NCT04593498) and a longitudinal study on progression of atrial fibrllation in the young (PRAY, NCT05080712).

Articles

All other publications

Selected grants

  • Swedish Research Council
    1 January 2024 - 31 December 2027
    The purpose of the trial is to study the prognostic impact of ECG investigation after stroke or Transient Ischemic Attack (TIA).The aim is to investigate if extended ECG screening after stroke or TIA as compared to standard ECG screening for atrial fibrillation reduces the occurrence of the primary composite endpoint of stroke, death and intracranial bleeding.P: Patients aged ≥70 years and admitted for ischemic stroke/TIA in Swedish stroke units. I: Extended long-term ECG-recording of 14 + 14 days duration using patch ECG, read in a core facility. Oral anticoagulation treatment will be suggested to all cases detected with atrial fibrillation in intervention and control arm unless contraindicated.C: Standard ECG recording of 48 hO: Primary outcome is a composite of stroke, all-cause mortality and intracerebral bleeding. Secondary and exploratory oucomes include the individual components of the primary endpoint, intracranial bleedning, myocardial infarction, major bleeding and pacemaker implantation. Endpoint and majority of baseline data will be collected from Swedish health care registers, mainly Riksstroke but also inpatient, drug prescription and cause of death register. Sample size is estimated at 2700. Pilot study commenced ni 2022, main trial is planned to recruit 2023-2026 and follow-up 2027-2028.Given a positive result, the study will give evidence to an investigation and treatment that will improve prognosis in a large group of patients with very poor prognosis.

Grants

Employments

  • Professor/Senior Consultant, Cardiology, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, 2024-

Supervision

  • Supervision to doctoral degree

    • Emma Svennberg, Screening for atrial fibrillation in high risk individuals - a stroke preventive effort, 2016
    • Katrin Kemp Gudmundsdottir, SCREENING FOR SILENT CARDIAC DISEASE IN AN ELDERLY POPULATION AIMING AT STROKE REDUCTION, 2020
    • Tove Hygrell, Implications of Brief Episodes of Atrial Fibrillation (Micro-AF), 2020
    • Adriano Atterman, ORAL ANTICOAGULANTS AS STROKE PREVENTION IN THE SETTING OF ATRIAL FIBRILLATION AND CANCER, 2020

Thesis evaluation

  • Loreta Skrebelyte Strøm, Opponent, Department of Cardiology, Akershus University Hospital (AHUS), Faculty of Medicine, University of Oslo, Norway, PREDICTION AND DETECTION OF OCCULT ATRIAL FIBRILLATION IN PATIENTS AFTER ACUTE CRYPTOGENIC STROKE AND TRANSIENT ISCHEMIC ATTACK, 2024
  • Marita Knudsen Pope, Opponent, Department of Cardiology, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Characteristics, treatment, and outcomes of patients newly diagnosed with atrial fibrillation -Insights from the GARFIELD-AF registry, 2024
  • Isabella Kharraziha, Opponent, Department of Clinical Sciences Malmö, Lund University, Novel diagnostic methods and potential treatments in cardiovascular autonomic dysfunction, 2024
  • Ole-Christian Rutherford, Opponent, Institute of Clinical Medicine, University of Oslo, Effectiveness and safety of oral anticoagulants for atrial fibrillation in the era of NOACs: Studies using Norwegian nationwide registries., 2022
  • Ekrem Yasa, Opponent, Department of Clinical Sciences, Malmö, Lund University, Cardiovascular Dysautonomia in older adults Aetiology, Diagnosis and Health related consequences, 2022

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