Jesse Huang

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Articles

Article: BRAIN. 2024;147(10):3573-3582
Genetics of immune response to Epstein-Barr virus: prospects for multiple sclerosis pathogenesis
Huang J; Tengvall K; Lima IB; Hedstroem AK; Butt J; Brenner N; Gyllenberg A; Stridh P; Khademi M; Ernberg I; Al Nimer F; Manouchehrinia A; Hillert J; Alfredsson L; Andersen O; Sundstroem P; Waterboer T; Olsson T; Kockum I
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2024;31(10):e16387
Rubella virus seropositivity after infection or vaccination as a risk factor for multiple sclerosis
Ingvarsson J; Grut V; Bistrom M; Berg LP; Stridh P; Huang J; Hillert J; Alfredsson L; Kockum I; Olsson T; Waterboer T; Nilsson S; Sundstrom P
Article: ANNALS OF NEUROLOGY. 2024;96(2):302-305
Interactions between High Seroreactivity to Human Herpes Virus 6A and Epstein-Barr Virus in MS Development: A Presymptomatic Case-Control Study
Grut V; Bistrom M; Salzer J; Stridh P; Jons D; Gustafsson R; Huang J; Bergstrom T; Kockum I; Waterboer T; Olsson T; Sundstrom P
Article: BRAIN. 2024;147(1):177-185
Human herpesvirus 6A and axonal injury before the clinical onset of multiple sclerosis
Grut V; Bistrom M; Salzer J; Stridh P; Jons D; Gustafsson R; Fogdell-Hahn A; Huang J; Butt J; Lindam A; Alonso-Magdalena L; Bergstrom T; Kockum I; Waterboer T; Olsson T; Zetterberg H; Blennow K; Andersen O; Nilsson S; Sundstroem P
Article: CURRENT PROTOCOLS. 2024;4(1):e972
Recovering Misidentified Samples Through Genetic Discordance Clustering
Huang J; Kockum I; Stridh P
Article: NATURE. 2023;619(7969):323-331
Locus for severity implicates CNS resilience in progression of multiple sclerosis
Harroud A; Stridh PJ; McCauley JH; Saarela J; van den Bosch AMR; Engelenburg H; Beecham A; Alfredsson L; Alikhani K; Amezcua L; Andlauer TFM; Ban M; Barcellos L; Barizzone N; Berge T; Berthele A; Bittner S; Bos S; Briggs FBS; Caillier S; Calabresi P; Caputo D; Carmona-Burgos D; Cavalla P; Celius E; Cerono G; Chinea A; Chitnis T; Clarelli F; Comabella M; Comi G; Cotsapas C; Cree BCA; D'Alfonso S; Dardiotis E; De Jager P; Delgado S; Dubois B; Engel S; Esposito F; Fabis-Pedrini M; Filippi M; Fitzgerald K; Gasperi C; Gomez L; Gomez R; Hadjigeorgiou G; Hamann J; Held F; Henry R; Hillert J; Huang J; Huitinga I; Islam T; Isobe N; Jagodic M; Kermode AL; Khalil M; Kilpatrick T; Konidari I; Kreft K; Lechner-Scott J; Leone M; Luessi F; Malhotra S; Manouchehrinia A; Manrique C; Martinelli-Boneschi F; Martinez A; Martinez-Maldonado V; Mascia E; Metz L; Midaglia L; Montalban X; Oksenberg J; Olsson T; Oturai A; Paakkonen K; Parnell GP; Patsopoulos N; Pericak-Vance M; Piehl F; Rubio J; Santaniello A; Santoro S; Schaefer C; Sellebjerg F; Shams H; Shchetynsky K; Silva C; Siokas V; Sondergaard H; Sorosina M; Taylor B; Vandebergh M; Vasileiou E; Vecchio D; Voortman M; Weiner H; Wever D; Yong VW; Hafler D; Stewart G; Compston A; Zipp F; Harbo H; Hemmer B; Goris A; Smolders J; Hauser S; Kockum I; Sawcer S; Baranzini S; Jonsdottir I; Blanco Y; Llufriu S; Madireddy L; Saiz A; Villoslada P; Stefansson K; Harbo HF; Hemmer B; Goris A; Kockum I; Sawcer SJ; Baranzini SE
Article: CURRENT PROTOCOLS. 2023;3(4):e727
Overview of Genotyping Technologies and Methods
Kockum I; Huang J; Stridh P
Article: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2022;68:104250
Trends in the environmental risks associated with earlier onset in multiple sclerosis
Huang J; Kockum I; Stridh P
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:930947
Plasma protein profiling reveals dynamic immunomodulatory changes in multiple sclerosis patients during pregnancy
Lingehed GP; Hellberg S; Huang J; Khademi M; Kockum I; Carlsson H; Tjernberg I; Svenvik M; Lind J; Blomberg M; Vrethem M; Mellergard J; Gustafsson M; Jenmalm MC; Olsson T; Ernerudh J
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:840158
Smoking Attributable Risk in Multiple Sclerosis
Manouchehrinia A; Huang J; Hillert J; Alfredsson L; Olsson T; Kockum I; Constantinescu CS
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2021;28(12):4146-4152
Low sun exposure acts synergistically with high Epstein-Barr nuclear antigen 1 (EBNA-1) antibody levels in multiple sclerosis etiology
Hedstrom AK; Huang J; Brenner N; Butt J; Kockum I; Waterboer T; Olsson T; Alfredsson L
Article: SCIENTIFIC REPORTS. 2021;11(1):20989
Seasonal variability of serum 25-hydroxyvitamin D on multiple sclerosis onset
Stridh P; Kockum I; Huang J
Article: MULTIPLE SCLEROSIS JOURNAL - EXPERIMENTAL, TRANSLATIONAL AND CLINICAL. 2021;7(4):20552173211065730
Season of birth is associated with multiple sclerosis and disease severity
Stridh P; Huang J; Hedstrom AK; Alfredsson L; Olsson T; Hillert J; Manouchehrinia A; Kockum I
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2021;28(9):3072-3079
Cytomegalovirus seropositivity is associated with reduced risk of multiple sclerosis-a presymptomatic case-control study
Grut V; Bistrom M; Salzer J; Stridh P; Jons D; Gustafsson R; Fogdell-Hahn A; Huang J; Brenner N; Butt J; Bender N; Lindam A; Alonso-Magdalena L; Gunnarsson M; Vrethem M; Bergstrom T; Andersen O; Kockum I; Waterboer T; Olsson T; Sundstrom P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(17):e2011574118
Small noncoding RNA profiling across cellular and biofluid compartments and their implications for multiple sclerosis immunopathology
Zheleznyakova GY; Piket E; Needhamsen M; Hagemann-Jensen M; Ekman D; Han Y; James T; Khademi M; Al Nimer F; Scicluna P; Huang J; Kockum I; Faridani OR; Olsson T; Piehl F; Jagodic M
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2021;28(2):579-586
Epstein-Barr virus infection after adolescence and human herpesvirus 6A as risk factors for multiple sclerosis
Bistrom M; Jons D; Engdahl E; Gustafsson R; Huang J; Brenner N; Butt J; Alonso-Magdalena L; Gunnarsson M; Vrethem M; Bender N; Waterboer T; Granasen G; Olsson T; Kockum I; Andersen O; Fogdell-Hahn A; Sundstrom P
Article: SCIENTIFIC REPORTS. 2021;11(1):1669
Differential effects on blood and cerebrospinal fluid immune protein markers and kynurenine pathway metabolites from aerobic physical exercise in healthy subjects
Isung J; Granqvist M; Trepci A; Huang J; Schwieler L; Kierkegaard M; Erhardt S; Jokinen J; Piehl F
Article: MOLECULAR & CELLULAR PROTEOMICS. 2021;20:100157
Assessing the Preanalytical Variability of Plasma and Cerebrospinal Fluid Processing and Its Effects on Inflammation-Related Protein Biomarkers
Huang J; Khademi M; Lindhe O; Jonsson G; Piehl F; Olsson T; Kockum I
Article: SCIENTIFIC REPORTS. 2020;10(1):10960
Smoking and Epstein-Barr virus infection in multiple sclerosis development
Hedstrom AK; Huang J; Brenner N; Butt J; Hillert J; Waterboer T; Kockum I; Olsson T; Alfredsson L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(23):12952-12960
Inflammation-related plasma and CSF biomarkers for sclerosis
Huang J; Khademi M; Fugger L; Lindhe O; Novakova L; Axelsson M; Malmestrom C; Constantinescu C; Lycke J; Piehl F; Olsson T; Kockum I
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(34):16955-16960
Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk
Tengvall K; Huang J; Hellstrom C; Kammer P; Bistrom M; Ayoglu B; Bomfim IL; Stridh P; Butt J; Brenner N; Michel A; Lundberg K; Padyukov L; Lundberg IE; Svenungsson E; Ernberg I; Olafsson S; Dilthey AT; Hillert J; Alfredsson L; Sundstrom P; Nilsson P; Waterboer T; Olsson T; Kockum I
Article: NATURE COMMUNICATIONS. 2019;10(1):3081
Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes
Carlstrom KE; Ewing E; Granqvist M; Gyllenberg A; Aeinehband S; Enoksson SL; Checa A; Badam TVS; Huang J; Gomez-Cabrero D; Gustafsson M; Al Nimer F; Wheelock CE; Kockum I; Olsson T; Jagodic M; Piehl F
Article: FRONTIERS IN NEUROLOGY. 2019;10:1368
High Levels of Epstein-Barr Virus Nuclear Antigen-1-Specific Antibodies and Infectious Mononucleosis Act Both Independently and Synergistically to Increase Multiple Sclerosis Risk
Hedstrom AK; Huang J; Michel A; Butt J; Brenner N; Hillert J; Waterboer T; Kockum I; Olsson T; Alfredsson L
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:2715
Increased Serological Response Against Human Herpesvirus 6A Is Associated With Risk for Multiple Sclerosis
Engdahl E; Gustafsson R; Huang J; Bistrom M; Bomfim IL; Stridh P; Khademi M; Brenner N; Butt J; Michel A; Jons D; Hortlund M; Alonso-Magdalena L; Hedstrom AK; Flamand L; Ihira M; Yoshikawa T; Andersen O; Hillert J; Alfredsson L; Waterboer T; Sundstrom P; Olsson T; Kockum I; Fogdell-Hahn A
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All other publications

Letter: MULTIPLE SCLEROSIS JOURNAL. 2024;30(10):1385-1386
From discovery to replication: Power and definitions matter for multiple sclerosis severity
Stridh P; Huang J; Kockum I
Letter: BRAIN, BEHAVIOR, AND IMMUNITY. 2023;113:302
Overlapping protein profile of first-episode psychosis patients and common handling markers may indicate presence of preanalytical variability A response to "Immunological protein profiling of first-episode psychosis patients identifies CSF and blood biomarkers correlating with disease severity" (2023)
Huang J; Olsson T; Kockum I
Preprint: MEDRXIV. 2023
Profiling abuse and neglect of women with disabilities: a step towards prevention of mistreatment of vulnerable populations
Savard J; Gavriilidis G; Lindblad A; Huang J; Adzemovic MZ
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:237-238
Antibody levels against human herpesvirus 6A and Epstein-Barr virus interact in the development of multiple sclerosis - a presymptomatic case-control study
Grut V; Bistrom M; Salzer J; Stridh P; Jons D; Gustafsson R; Huang J; Bergstrom T; Kockum I; Waterboer T; Olsson T; Andersen OA; Sundstrom P
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:300-301
Differentiating multiple sclerosis through the proteomic profiling of metabolic and neurological processes
Huang J; Nyren LN; Axelsson M; Malmestrom C; Khademi M; Piehl F; Constantinescu C; Lycke J; Olsson T; Kockum I
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:105
LowSun Exposure Interacts With High EBNA-Antibody Levels in MS Etiology
Alfredsson L; Huang J; Brenner N; Butt J; Strid P; Kockum I; Waterboer T; Olsson T; Hedstrom AK
Preprint: MEDRXIV. 2022
Plasma protein profiling of multiple sclerosis using proximity extension assays
Huang J; Khademi M; Piehl F; Olsson T; Kockum I
Thesis / dissertation: 2022
Biomarkers and viral risk factors in multiple sclerosis
Huang, Jesse
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):86-87
Increase in Epstein Barr virus serologies precedes neuroaxonal damage in pre-symptomatic multiple sclerosis
Jons D; Bergstroem T; Zetterberg H; Bistroem M; Alonso-Magdalena L; Gunnarsson M; Vrethem M; Blennow K; Nilsson S; Huang J; Kockum I; Olsson T; Waterboer T; Sundstroem P; Andersen O
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):590
Identifying multiple sclerosis biomarkers in blood using high-sensitivity technologies
Huang J; Khademi M; Piehl F; Olsson T; Kockum I
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(1_SUPPL):31
Dynamic Changes of Protein Levels in MS Patients during Pregnancy
Papapavlou G; Hellberg S; Huang J; Svenvik M; Jenmalm MC; Gustafsson M; Olsson T; Ernerudh J
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):506-507
Genetic susceptibility to multiple sclerosis is associated with earlier onset and increased disease severity
Huang J; Stridh P; Manouchehrinia A; Gyllenberg A; Alfredsson L; Hillert J; Olsson T; Kockum I
Preprint: MEDRXIV. 2021
IgG index and not serum 25-hydroxyvitamin D is associated with age at onset of multiple sclerosis
Stridh P; Kockum I; Huang J
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):372
High levels of Epstein-Barr virus nuclear antigen-1 specific antibodies and infectious mononucleosis act both independently and synergistically to increase multiple sclerosis risk
Olsson T; Hedstrom A; Huang J; Michel A; Butt J; Brenner N; Hillert J; Waterboer T; Kockum I; Alfredsson L
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):664
Clinical, life-style and genetic determinants of response to natalizumab: a 13-year nationwide Phase IV study
Manouchehrinia A; Larsson H; Karim ME; Huang J; Kockum I; Olsson T
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):371-372
Smoking and Epstein-Barr virus infection in multiple sclerosis development
Alfredsson L; Hedstrom A; Huang J; Brenner N; Butt J; Hillert J; Waterboer T; Kockum I; Olsson T
Preprint: MEDRXIV. 2020
Comparing biomarkers for COVID-19 disease with commonly associated preexisting conditions and complications
Huang J
Preprint: 2020
Interaction between two exposures: determining odds ratios and confidence intervals for risk estimates
Huang J; Kockum I; Stridh P
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2020;26(3_SUPPL):197
Smoking is associated with increased plasma neurofilament light levels in multiple sclerosis
Manouchehrinia A; Larsson H; Huang J; Alfredsson L; Piehl F; Kuhle J; Olsson T; Kockum I
Preprint: BIORXIV. 2019
Increased serological response against human herpesvirus 6A is associated with risk for multiple sclerosis
Engdahl E; Gustafsson R; Huang J; Biström M; Bomfim IL; Stridh P; Khademi M; Brenner N; Butt J; Michel A; Jons D; Hortlund M; Alonso-Magdalena L; Hedström AK; Flamand L; Ihira M; Yoshikawa T; Andersen O; Hillert J; Alfredsson L; Waterboer T; Sundström P; Olsson T; Kockum I; Fogdell-Hahn A
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2019;25:930
Blocking PDGFR-a decreases multiple sclerosis-like neuroinflammation by inhibiting disruption of blood brain barrier integrity
Zeitelhofer M; Adzemovic MZ; Huang J; Stefanitsch C; Mossinger C; Hochmeister S; Strell C; Muhl L; Lassmann H; Kockum I; Fredriksson L; Olsson T; Nilsson I; Eriksson U
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2019;25:81-82
Serological response against HHV-6A is associated with increased risk for multiple sclerosis
Engdahl E; Gustafsson R; Huang J; Bistrom M; Bomfim IL; Stridh P; Khademi M; Brenner N; Butt J; Michel A; Jons D; Hortlund M; Alonso-Magdalena L; Hedstrom AK; Flamand L; Ihira M; Yoshikawa T; Andersen O; Hillert J; Alfredsson L; Waterboer T; Sundstrom P; Olsson T; Kockum I; Fogdell-Hahn A
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2019;25:498
Inflammation-related plasma and cerebrospinal fluid biomarkers for multiple sclerosis
Huang J; Khademi M; Fugger L; Piehl F; Olsson T; Kockum I
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2018;24:64
Molecular mimicry between the autoantigen Anoctamin 2 and Epstein Barr virus nuclear antigen 1 associates with increased risk for multiple sclerosis.
Olsson T; Huang J; Hellstrom C; Tengvall K; Kammer P; Bistrom M; Bomfim IL; Stridh P; Butt J; Nicole B; Michel A; Ayoglu B; Lundberg K; Lundberg I; Olafsson S; Jonsdottir I; Stefansson K; Dilthey A; Hillert J; Alfredsson L; Sundstrom P; Nilsson P; Waterboer T; Kockum I
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2016;22:746
Anoctamin 2 as a multiple sclerosis autoantigen - replication of antibody reactivity in a larger cohort
Tengvall K; Bomfim IL; Michel A; Huang J; Ayoglu B; Alfredsson L; Nilsson P; Waterboer T; Olsson T; Kockum I
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2016;22:187
Late Epstein-Barr virus infection and a second virus are linked to multiple sclerosis risk
Bistrom M; Gustafsson R; Engdahl E; Bomfim IL; Huang J; Jons D; Andersen O; Hortlund M; Alonso-Magdalena L; Waterboer T; Kockum I; Olsson T; Fogdell-Hahn A; Sundstrom P
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2016;22:859-860
Serological response against an immediately early protein 1 (IE1) protein sequence from HHV-6A, but not HHV-6B, is positively associated with multiple sclerosis
Engdahl E; Gustafsson R; Huang J; Bomfim IL; Khademi M; Michel A; Butt J; Brenner N; Hillert J; Alfredsson L; Waterboer T; Olsson T; Kockum I; Fogdell-Hahn A
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2016;22:497
Genetic association of HLA alleles with JC polyomavirus and cross-reactivity with BK polyomavirus
Huang J; Bomfim IL; Michel A; Link J; Khademi M; Warnke C; Hillert J; Alfredsson L; Waterboer T; Olsson T; Kockum I
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Grants

Research Grant
Multiple Sclerosis Research Foundation
1 November 2022 - 1 November 2023

Employments

Postdoctoral Researcher, Department of Clinical Neuroscience, Karolinska Institutet, 2024-2026

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2022

Articles

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Degrees and Education

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