Jesse Huang

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Articles

Article: BRAIN. 2024;:awae110

Genetics of immune response to Epstein-Barr virus: prospects for multiple sclerosis pathogenesis.

Huang J; Tengvall K; Bomfim Lima I; Hedström AK; Butt J; Brenner N; Gyllenberg A; Stridh P; Khademi M; Ernberg I; Al Nimer F; Manouchehrinia A; Hillert J; Alfredsson L; Andersen O; Sundström P; Waterboer T; Olsson T; Kockum I
Article: BRAIN. 2024;147(1):177-185

Human herpesvirus 6A and axonal injury before the clinical onset of multiple sclerosis.

Grut V; Biström M; Salzer J; Stridh P; Jons D; Gustafsson R; Fogdell-Hahn A; Huang J; Butt J; Lindam A; Alonso-Magdalena L; Bergström T; Kockum I; Waterboer T; Olsson T; Zetterberg H; Blennow K; Andersen O; Nilsson S; Sundström P
Article: CURRENT PROTOCOLS. 2024;4(1):e972

Recovering Misidentified Samples Through Genetic Discordance Clustering.

Huang J; Kockum I; Stridh P
Article: NATURE. 2023;619(7969):323-331

Locus for severity implicates CNS resilience in progression of multiple sclerosis.

International Multiple Sclerosis Genetics Consorti; MultipleMS Consortium
Article: CURRENT PROTOCOLS. 2023;3(4):e727

Overview of Genotyping Technologies and Methods.

Kockum I; Huang J; Stridh P
Article: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2022;68:104250

Trends in the environmental risks associated with earlier onset in multiple sclerosis.

Huang J; Kockum I; Stridh P
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:840158

Smoking Attributable Risk in Multiple Sclerosis.

Manouchehrinia A; Huang J; Hillert J; Alfredsson L; Olsson T; Kockum I; Constantinescu CS
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:930947

Plasma protein profiling reveals dynamic immunomodulatory changes in multiple sclerosis patients during pregnancy.

Papapavlou Lingehed G; Hellberg S; Huang J; Khademi M; Kockum I; Carlsson H; Tjernberg I; Svenvik M; Lind J; Blomberg M; Vrethem M; Mellergård J; Gustafsson M; Jenmalm MC; Olsson T; Ernerudh J
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2021;28(12):4146-4152

Low sun exposure acts synergistically with high Epstein-Barr nuclear antigen 1 (EBNA-1) antibody levels in multiple sclerosis etiology.

Hedström AK; Huang J; Brenner N; Butt J; Kockum I; Waterboer T; Olsson T; Alfredsson L
Article: SCIENTIFIC REPORTS. 2021;11(1):20989

Seasonal variability of serum 25-hydroxyvitamin D on multiple sclerosis onset.

Stridh P; Kockum I; Huang J
Article: MULTIPLE SCLEROSIS JOURNAL - EXPERIMENTAL, TRANSLATIONAL AND CLINICAL. 2021;7(4):20552173211065730-205521732110657

Season of birth is associated with multiple sclerosis and disease severity.

Stridh P; Huang J; Hedström AK; Alfredsson L; Olsson T; Hillert J; Manouchehrinia A; Kockum I
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2021;28(9):3072-3079

Cytomegalovirus seropositivity is associated with reduced risk of multiple sclerosis-a presymptomatic case-control study.

Grut V; Biström M; Salzer J; Stridh P; Jons D; Gustafsson R; Fogdell-Hahn A; Huang J; Brenner N; Butt J; Bender N; Lindam A; Alonso-Magdalena L; Gunnarsson M; Vrethem M; Bergström T; Andersen O; Kockum I; Waterboer T; Olsson T; Sundström P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(17):e2011574118

Small noncoding RNA profiling across cellular and biofluid compartments and their implications for multiple sclerosis immunopathology.

Zheleznyakova GY; Piket E; Needhamsen M; Hagemann-Jensen M; Ekman D; Han Y; James T; Khademi M; Al Nimer F; Scicluna P; Huang J; Kockum I; Faridani OR; Olsson T; Piehl F; Jagodic M
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2021;28(2):579-586

Epstein-Barr virus infection after adolescence and human herpesvirus 6A as risk factors for multiple sclerosis.

Biström M; Jons D; Engdahl E; Gustafsson R; Huang J; Brenner N; Butt J; Alonso-Magdalena L; Gunnarsson M; Vrethem M; Bender N; Waterboer T; Granåsen G; Olsson T; Kockum I; Andersen O; Fogdell-Hahn A; Sundström P
Article: SCIENTIFIC REPORTS. 2021;11(1):1669

Differential effects on blood and cerebrospinal fluid immune protein markers and kynurenine pathway metabolites from aerobic physical exercise in healthy subjects.

Isung J; Granqvist M; Trepci A; Huang J; Schwieler L; Kierkegaard M; Erhardt S; Jokinen J; Piehl F
Article: MOLECULAR & CELLULAR PROTEOMICS. 2021;20:100157

Assessing the Preanalytical Variability of Plasma and Cerebrospinal Fluid Processing and Its Effects on Inflammation-Related Protein Biomarkers.

Huang J; Khademi M; Lindhe Ö; Jönsson G; Piehl F; Olsson T; Kockum I
Article: SCIENTIFIC REPORTS. 2020;10(1):10960

Smoking and Epstein-Barr virus infection in multiple sclerosis development.

Hedström AK; Huang J; Brenner N; Butt J; Hillert J; Waterboer T; Kockum I; Olsson T; Alfredsson L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(23):12952-12960

Inflammation-related plasma and CSF biomarkers for multiple sclerosis.

Huang J; Khademi M; Fugger L; Lindhe Ö; Novakova L; Axelsson M; Malmeström C; Constantinescu C; Lycke J; Piehl F; Olsson T; Kockum I
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(34):16955-16960

Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk.

Tengvall K; Huang J; Hellström C; Kammer P; Biström M; Ayoglu B; Lima Bomfim I; Stridh P; Butt J; Brenner N; Michel A; Lundberg K; Padyukov L; Lundberg IE; Svenungsson E; Ernberg I; Olafsson S; Dilthey AT; Hillert J; Alfredsson L; Sundström P; Nilsson P; Waterboer T; Olsson T; Kockum I
Article: NATURE COMMUNICATIONS. 2019;10(1):3081

Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes.

Carlström KE; Ewing E; Granqvist M; Gyllenberg A; Aeinehband S; Enoksson SL; Checa A; Badam TVS; Huang J; Gomez-Cabrero D; Gustafsson M; Al Nimer F; Wheelock CE; Kockum I; Olsson T; Jagodic M; Piehl F
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:2715

Increased Serological Response Against Human Herpesvirus 6A Is Associated With Risk for Multiple Sclerosis.

Engdahl E; Gustafsson R; Huang J; Biström M; Lima Bomfim I; Stridh P; Khademi M; Brenner N; Butt J; Michel A; Jons D; Hortlund M; Alonso-Magdalena L; Hedström AK; Flamand L; Ihira M; Yoshikawa T; Andersen O; Hillert J; Alfredsson L; Waterboer T; Sundström P; Olsson T; Kockum I; Fogdell-Hahn A
Article: FRONTIERS IN NEUROLOGY. 2019;10:1368

High Levels of Epstein-Barr Virus Nuclear Antigen-1-Specific Antibodies and Infectious Mononucleosis Act Both Independently and Synergistically to Increase Multiple Sclerosis Risk.

Hedström AK; Huang J; Michel A; Butt J; Brenner N; Hillert J; Waterboer T; Kockum I; Olsson T; Alfredsson L
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All other publications

Letter: BRAIN BEHAVIOR AND IMMUNITY. 2023;113:302

Overlapping protein profile of first-episode psychosis patients and common handling markers may indicate presence of preanalytical variability: A response to "Immunological protein profiling of first-episode psychosis patients identifies CSF and blood biomarkers correlating with disease severity" (2023).

Huang J; Olsson T; Kockum I
Preprint: MEDRXIV. 2023

Profiling abuse and neglect of women with disabilities: a step towards prevention of mistreatment of vulnerable populations

Savard J; Gavriilidis G; Lindblad A; Huang J; Adzemovic MZ
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:105

LowSun Exposure Interacts With High EBNA-Antibody Levels in MS Etiology

Alfredsson L; Huang J; Brenner N; Butt J; Strid P; Kockum I; Waterboer T; Olsson T; Hedstrom AK
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:237-238

Antibody levels against human herpesvirus 6A and Epstein-Barr virus interact in the development of multiple sclerosis - a presymptomatic case-control study

Grut V; Bistrom M; Salzer J; Stridh P; Jons D; Gustafsson R; Huang J; Bergstrom T; Kockum I; Waterboer T; Olsson T; Andersen OA; Sundstrom P
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:300-301

Differentiating multiple sclerosis through the proteomic profiling of metabolic and neurological processes

Huang J; Nyren LN; Axelsson M; Malmestrom C; Khademi M; Piehl F; Constantinescu C; Lycke J; Olsson T; Kockum I
Preprint: MEDRXIV. 2022

Plasma protein profiling of multiple sclerosis using proximity extension assays

Huang J; Khademi M; Piehl F; Olsson T; Kockum I
Thesis / dissertation: 2022

Biomarkers and viral risk factors in multiple sclerosis

Huang, Jesse
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):86-87

Increase in Epstein Barr virus serologies precedes neuroaxonal damage in pre-symptomatic multiple sclerosis

Jons D; Bergstroem T; Zetterberg H; Bistroem M; Alonso-Magdalena L; Gunnarsson M; Vrethem M; Blennow K; Nilsson S; Huang J; Kockum I; Olsson T; Waterboer T; Sundstroem P; Andersen O
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):590

Identifying multiple sclerosis biomarkers in blood using high-sensitivity technologies

Huang J; Khademi M; Piehl F; Olsson T; Kockum I
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):506-507

Genetic susceptibility to multiple sclerosis is associated with earlier onset and increased disease severity

Huang J; Stridh P; Manouchehrinia A; Gyllenberg A; Alfredsson L; Hillert J; Olsson T; Kockum I
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(1_SUPPL):31

Dynamic Changes of Protein Levels in MS Patients during Pregnancy

Papapavlou G; Hellberg S; Huang J; Svenvik M; Jenmalm MC; Gustafsson M; Olsson T; Ernerudh J
Preprint: MEDRXIV. 2021

IgG index and not serum 25-hydroxyvitamin D is associated with age at onset of multiple sclerosis

Stridh P; Kockum I; Huang J
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):664

Clinical, life-style and genetic determinants of response to natalizumab: a 13-year nationwide Phase IV study

Manouchehrinia A; Larsson H; Karim ME; Huang J; Kockum I; Olsson T
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):371-372

Smoking and Epstein-Barr virus infection in multiple sclerosis development

Alfredsson L; Hedstrom A; Huang J; Brenner N; Butt J; Hillert J; Waterboer T; Kockum I; Olsson T
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):372

High levels of Epstein-Barr virus nuclear antigen-1 specific antibodies and infectious mononucleosis act both independently and synergistically to increase multiple sclerosis risk

Olsson T; Hedstrom A; Huang J; Michel A; Butt J; Brenner N; Hillert J; Waterboer T; Kockum I; Alfredsson L
Preprint: MEDRXIV. 2020

Comparing biomarkers for COVID-19 disease with commonly associated preexisting conditions and complications

Huang J
Preprint: 2020

Interaction between two exposures: determining odds ratios and confidence intervals for risk estimates

Huang J; Kockum I; Stridh P
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2020;26(3_SUPPL):197

Smoking is associated with increased plasma neurofilament light levels in multiple sclerosis

Manouchehrinia A; Larsson H; Huang J; Alfredsson L; Piehl F; Kuhle J; Olsson T; Kockum I
Preprint: BIORXIV. 2019

Increased serological response against human herpesvirus 6A is associated with risk for multiple sclerosis

Engdahl E; Gustafsson R; Huang J; Biström M; Bomfim IL; Stridh P; Khademi M; Brenner N; Butt J; Michel A; Jons D; Hortlund M; Alonso-Magdalena L; Hedström AK; Flamand L; Ihira M; Yoshikawa T; Andersen O; Hillert J; Alfredsson L; Waterboer T; Sundström P; Olsson T; Kockum I; Fogdell-Hahn A
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2019;25:81-82

Serological response against HHV-6A is associated with increased risk for multiple sclerosis

Engdahl E; Gustafsson R; Huang J; Bistrom M; Bomfim IL; Stridh P; Khademi M; Brenner N; Butt J; Michel A; Jons D; Hortlund M; Alonso-Magdalena L; Hedstrom AK; Flamand L; Ihira M; Yoshikawa T; Andersen O; Hillert J; Alfredsson L; Waterboer T; Sundstrom P; Olsson T; Kockum I; Fogdell-Hahn A
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2019;25:930

Blocking PDGFR-a decreases multiple sclerosis-like neuroinflammation by inhibiting disruption of blood brain barrier integrity

Zeitelhofer M; Adzemovic MZ; Huang J; Stefanitsch C; Mossinger C; Hochmeister S; Strell C; Muhl L; Lassmann H; Kockum I; Fredriksson L; Olsson T; Nilsson I; Eriksson U
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2019;25:498

Inflammation-related plasma and cerebrospinal fluid biomarkers for multiple sclerosis

Huang J; Khademi M; Fugger L; Piehl F; Olsson T; Kockum I
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2018;24:64

Molecular mimicry between the autoantigen Anoctamin 2 and Epstein Barr virus nuclear antigen 1 associates with increased risk for multiple sclerosis.

Olsson T; Huang J; Hellstrom C; Tengvall K; Kammer P; Bistrom M; Bomfim IL; Stridh P; Butt J; Nicole B; Michel A; Ayoglu B; Lundberg K; Lundberg I; Olafsson S; Jonsdottir I; Stefansson K; Dilthey A; Hillert J; Alfredsson L; Sundstrom P; Nilsson P; Waterboer T; Kockum I
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2016;22:746

Anoctamin 2 as a multiple sclerosis autoantigen - replication of antibody reactivity in a larger cohort

Tengvall K; Bomfim IL; Michel A; Huang J; Ayoglu B; Alfredsson L; Nilsson P; Waterboer T; Olsson T; Kockum I
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2016;22:859-860

Serological response against an immediately early protein 1 (IE1) protein sequence from HHV-6A, but not HHV-6B, is positively associated with multiple sclerosis

Engdahl E; Gustafsson R; Huang J; Bomfim IL; Khademi M; Michel A; Butt J; Brenner N; Hillert J; Alfredsson L; Waterboer T; Olsson T; Kockum I; Fogdell-Hahn A
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2016;22:187

Late Epstein-Barr virus infection and a second virus are linked to multiple sclerosis risk

Bistrom M; Gustafsson R; Engdahl E; Bomfim IL; Huang J; Jons D; Andersen O; Hortlund M; Alonso-Magdalena L; Waterboer T; Kockum I; Olsson T; Fogdell-Hahn A; Sundstrom P
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2016;22:497

Genetic association of HLA alleles with JC polyomavirus and cross-reactivity with BK polyomavirus

Huang J; Bomfim IL; Michel A; Link J; Khademi M; Warnke C; Hillert J; Alfredsson L; Waterboer T; Olsson T; Kockum I
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Grants

Research Grant

Multiple Sclerosis Research Foundation

1 November 2022 - 1 November 2023

Employments

Postdoctoral Researcher, Department of Clinical Neuroscience, Karolinska Institutet, 2024-2026

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2022

Articles

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