Jacob Bergstedt

Publications
CV
Public outreach and news

Articles

Article: JAMA PSYCHIATRY. 2024;81(6):586-594

Adverse Childhood Experiences and Adult Mental Health Outcomes

Danielsdottir HB; Aspelund T; Shen Q; Halldorsdottir T; Jakobsdottir J; Song H; Lu D; Kuja-Halkola R; Larsson H; Fall K; Magnusson PKE; Fang F; Bergstedt J; Valdimarsdottir UA
Journal article: NAT CARDIOVASC RES. 2024;3(6):754-769

Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease.

Bergstedt J; Pasman JA; Ma Z; Harder A; Yao S; Parker N; Treur JL; Smit DJA; Frei O; Shadrin AA; Meijsen JJ; Shen Q; Hägg S; Tornvall P; Buil A; Werge T; Hjerling-Leffler J; Als TD; Børglum AD; Lewis CM; McIntosh AM; Valdimarsdóttir UA; Andreassen OA; Sullivan PF; Lu Y; Fang F
Article: NATURE. 2024;626(8000):827-835

Smoking changes adaptive immunity with persistent effects

Saint-Andre V; Charbit B; Biton A; Rouilly V; Posseme C; Bertrand A; Rotival M; Bergstedt J; Patin E; Albert ML; Quintana-Murci L; Duffy D
Article: ECLINICALMEDICINE. 2023;61:102063

Psychiatric disorders and subsequent risk of cardiovascular disease: a longitudinal matched cohort study across three countries

Shen Q; Mikkelsen DH; Luitva LB; Song H; Kasela S; Aspelund T; Bergstedt J; Lu Y; Sullivan PF; Ye W; Fall K; Tornvall P; Pawitan Y; Andreassen OA; Buil A; Milani L; Fang F; Valdimarsdottir U
Article: LANCET REGIONAL HEALTH-EUROPE. 2023;29:100621

Epidemiological overview of major depressive disorder in Scandinavia using nationwide registers

Pasman JA; Meijsen J; Haram M; Kowalec K; Harder A; Xiong Y; Nguyen T-D; Jangmo A; Shorter JR; Bergstedt J; Das U; Zetterberg R; Tate A; Lichtenstein P; Larsson H; Odsbu I; Werge T; Reichborn-Kjennerud T; Andreassen OA; Sullivan PF; Buil A; Tesli M; Lua Y
Article: CURRENT BIOLOGY. 2022;32(21):4565-4575.e6

The genomic landscape of contemporary western Remote Oceanians

Arauna LR; Bergstedt J; Choin J; Mendoza-Revilla J; Harmant C; Roux M; Mas-Sandoval A; Lemee L; Colleran H; Francois A; Valentin F; Cassar O; Gessain A; Quintana-Murci L; Patin E
Article: ELIFE. 2022;11:e80143

Cardiovascular disease and subsequent risk of psychiatric disorders: a nationwide sibling-controlled study

Shen Q; Song H; Aspelund T; Yu J; Lu D; Jakobsdottir J; Bergstedt J; Yi L; Sullivan P; Sjolander A; Ye W; Fall K; Fang F; Valdimarsdottir U
Article: NATURE COMMUNICATIONS. 2022;13(1):5895

The immune factors driving DNA methylation variation in human blood

Bergstedt J; Azzou SAK; Tsuo K; Jaquaniello A; Urrutia A; Rotival M; Lin DTS; MacIsaac JL; Kobor MS; Albert ML; Duffy D; Patin E; Quintana-Murci L
Article: CELL REPORTS. 2022;39(13):110989

Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation

Posseme C; Llibre A; Charbit B; Bondet V; Rouilly V; Saint-Andre V; Boussier J; Bergstedt J; Smith N; Townsend L; Sugrue JA; Cheallaigh CN; Conlon N; Rotival M; Kobor MS; Mottez E; Pol S; Patin E; Albert ML; Quintana-Murci L; Duffy D
Article: BMC CANCER. 2022;22(1):680

Neuroendocrine pathways and breast cancer progression: a pooled analysis of somatic mutations and gene expression from two large breast cancer cohorts

Hu K; Wang C; Luo C; Zheng H; Song H; Bergstedt J; Fall K; Luo T; Czene K; Valdimarsdottir UA; Fang F; Lu D
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2021;218(1):e20200606

Gut microbiome stability and dynamics in healthy donors and patients with non-gastrointestinal cancers.

Byrd AL; Liu M; Fujimura KE; Lyalina S; Nagarkar DR; Charbit B; Bergstedt J; Patin E; Harrison OJ; Quintana-Murci L; Mellman I; Duffy D; Albert ML; Milieu Intérieur Consortium
Article: NATURE COMMUNICATIONS. 2020;11(1):363

Machine learning can identify newly diagnosed patients with CLL at high risk of infection.

Agius R; Brieghel C; Andersen MA; Pearson AT; Ledergerber B; Cozzi-Lepri A; Louzoun Y; Andersen CL; Bergstedt J; von Stemann JH; Jørgensen M; Tang M-HE; Fontes M; Bahlo J; Herling CD; Hallek M; Lundgren J; MacPherson CR; Larsen J; Niemann CU
Article: MICROBIOME. 2019;7(1):130

A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals.

Scepanovic P; Hodel F; Mondot S; Partula V; Byrd A; Hammer C; Alanio C; Bergstedt J; Patin E; Touvier M; Lantz O; Albert ML; Duffy D; Quintana-Murci L; Fellay J; Milieu Intérieur Consortium
Article: SCIENCE TRANSLATIONAL MEDICINE. 2018;10(457):eaao2966

Human thymopoiesis is influenced by a common genetic variant within the TCRA-TCRD locus.

Clave E; Araujo IL; Alanio C; Patin E; Bergstedt J; Urrutia A; Lopez-Lastra S; Li Y; Charbit B; MacPherson CR; Hasan M; Melo-Lima BL; Douay C; Saut N; Germain M; Trégouët D-A; Morange P-E; Fontes M; Duffy D; Di Santo JP; Quintana-Murci L; Albert ML; Toubert A; Milieu Intérieur Consortium
Article: GENOME MEDICINE. 2018;10(1):59

Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines.

Scepanovic P; Alanio C; Hammer C; Hodel F; Bergstedt J; Patin E; Thorball CW; Chaturvedi N; Charbit B; Abel L; Quintana-Murci L; Duffy D; Albert ML; Fellay J; Milieu Intérieur Consortium
Article: NATURE IMMUNOLOGY. 2018;19(3):302-314

Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.

Patin E; Hasan M; Bergstedt J; Rouilly V; Libri V; Urrutia A; Alanio C; Scepanovic P; Hammer C; Jönsson F; Beitz B; Quach H; Lim YW; Hunkapiller J; Zepeda M; Green C; Piasecka B; Leloup C; Rogge L; Huetz F; Peguillet I; Lantz O; Fontes M; Di Santo JP; Thomas S; Fellay J; Duffy D; Quintana-Murci L; Albert ML; Milieu Intérieur Consortium
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2018;115(3):E488-E497

Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges.

Piasecka B; Duffy D; Urrutia A; Quach H; Patin E; Posseme C; Bergstedt J; Charbit B; Rouilly V; MacPherson CR; Hasan M; Albaud B; Gentien D; Fellay J; Albert ML; Quintana-Murci L; Milieu Intérieur Consortium

All other publications

Preprint: MEDRXIV. 2024;MEDRXIV

Quantifying the Relative Importance of Genetics and Environment on the Comorbidity between Mental- and Cardiometabolic Disorders: A Comprehensive Analysis of National Register Data from 17 million Scandinavians.

Meijsen J; Hu K; Krebs MD; Athanasiadis G; Washbrook S; Zetterberg R; E Silva RNA; Shorter JR; Gådin JR; Bergstedt J; Howard DM; Ye W; iPSYCH Consortium; Lu Y; Valdimarsdóttir UA; Ingason A; Mikkelsen DH; Plana-Ripoll O; McGrath JJ; Micali N; Andreassen OA; Werge TM; Fang F; Buil A
Preprint: MEDRXIV. 2024;MEDRXIV

Distinct genomic signatures and modifiable risk factors underly the comorbidity between major depressive disorder and cardiovascular disease.

Bergstedt J; Pasman JA; Ma Z; Harder A; Yao S; Parker N; Treur JL; Smit DJA; Frei O; Shadrin A; Meijsen JJ; Shen Q; Hägg S; Tornvall P; Buil A; Werge T; Hjerling-Leffler J; Als TD; Børglum AD; Lewis CM; McIntosh AM; Valdimarsdóttir UA; Andreassen OA; Sullivan PF; Lu Y; Fang F
Preprint: MEDRXIV. 2023;MEDRXIV

Associations of schizophrenia with arrhythmic disorders and electrocardiogram traits: an in-depth genetic exploration of population samples.

Treur JL; Thijssen AB; Smit DJ; Tadros R; Veeneman RR; Denys D; Vermeulen JM; Barc J; Bergstedt J; Pasman JA; Bezzina CR; Verweij KJH

Employments

Postdoctoral Researcher, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2022-2025
Postdoctoral Researcher, Institute of Environmental Medicine, Karolinska Institutet, 2020-2025

Articles

All other publications

Employments

News from KI

Events from KI