Jaakko Patrakka
Researcher | Docent
E-mail: jaakko.patrakka@ki.se
Telephone: +46852483595
Visiting address: Nobels väg 7, 17165 Solna
Postal address: H5 Laboratoriemedicin, H5 Patologi Patrakka, 141 52 Huddinge
About me
- Adjunct Professor of Pathology at the Department of Laboratory Medicine as of
1 September 2020. Primary position: Doctor at Karolinska University Hospital
Research
- Jaakko Patrakka is a clinical pathologist and researches kidney function and
the mecha- nisms of chronic kidney disease. More specifically he is studying
glomeruli – the network of millions of capillaries in the kidneys that
produces primary urine. Glomerular diseases are the most common cause of
death by kidney failure. With a better understanding of glomeruli and their
diseases, Jaakko Patrakka hopes to contribute to the development of new
diagnostic and prognostic tools and new drugs.
His research involves the use of genetic and molecular tools, and spans the
mapping of mechanisms in animal models to the search for biomarkers in
patient material. Single-cell sequencing has also enabled Jaakko Patrakka’s
group to characterise different cell types in the kidneys’ heterogeneous
tissue, which has led to the discovery of a previously unknown glomerular
cell type.
The group is also collaborating with AstraZeneca on the development of new
drug candidates.
Articles
- Journal article: SCIENTIFIC REPORTS. 2024;14(1):11850
- Article: KIDNEY INTERNATIONAL. 2023;103(6):1120-1130
- Article: COMMUNICATIONS BIOLOGY. 2023;6(1):208
- Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2023;38(2):311-321
- Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2022;33(11):2008-2025
- Article: KIDNEY INTERNATIONAL. 2022;101(4):752-765
- Article: KIDNEY INTERNATIONAL. 2021;100(4):809-823
- Article: NATURE COMMUNICATIONS. 2021;12(1):2141
- Article: KIDNEY INTERNATIONAL. 2021;99(4):1010-1020
- Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2020;35(12):2059-2072
- Article: SCIENTIFIC REPORTS. 2020;10(1):20037
- Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2019;30(9):1573-1586
- Article: SCIENTIFIC REPORTS. 2019;9(1):8888
- Article: KIDNEY INTERNATIONAL. 2018;94(6):1099-1110
- Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2018;29(6):1679-1689
- Article: KIDNEY INTERNATIONAL. 2018;93(4):1008-1013
- Article: SCIENTIFIC REPORTS. 2018;8(1):4712
- Article: PLOS ONE. 2018;13(8):e0202400
- Article: CLINICAL AND EXPERIMENTAL NEPHROLOGY. 2017;21(4):677-684
- Article: CELL METABOLISM. 2017;25(3):713-726
- Article: JCI INSIGHT. 2016;1(9):86177
- Article: AMERICAN JOURNAL OF PHYSIOLOGY - RENAL PHYSIOLOGY. 2015;309(11):F955-F966
- Article: AMERICAN JOURNAL OF PATHOLOGY. 2015;185(8):2143-2157
- Article: PLOS ONE. 2015;10(3):e0122067
- Article: PEDIATRIC NEPHROLOGY. 2013;28(2):339-343
- Article: PLOS ONE. 2013;8(8):e72750
- Article: PLOS ONE. 2013;8(12):e83133
- Article: KIDNEY INTERNATIONAL. 2013;83(1):63-71
- Article: KIDNEY INTERNATIONAL. 2012;82(10):1071-1083
- Article: DEVELOPMENTAL DYNAMICS. 2011;240(12):2646-2656
- Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2011;22(11):2037-2046
- Article: KIDNEY INTERNATIONAL. 2011;80(10):1045-1054
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2011;121(10):3965-3980
- Article: NEPHRON. 2011;118(3):e39-e48
- Article: NEPHRON. 2011;117(2):e39-e46
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;396(1):164-169
- Article: NEPHRON. 2010;116(2):e42-e52
- Article: AMERICAN JOURNAL OF NEPHROLOGY. 2009;29(6):558-570
- Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2008;23(8):2504-2511
- Article: TRANSPLANTATION. 2007;83(10):1316-1323
- Article: KIDNEY INTERNATIONAL. 2007;71(9):889-900
- Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2007;18(3):689-697
- Article: NEPHRON. 2007;106(2):e32-e36
- Article: EMBO JOURNAL. 2006;25(5):1160-1174
- Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2004;15(10):2611-2618
- Article: PEDIATRIC RESEARCH. 2004;55(5):774-781
- Article: PEDIATRIC RESEARCH. 2002;52(3):349-355
- Article: THE LANCET. 2002;359(9317):1575-1577
- Article: TRANSPLANTATION. 2002;73(3):394-403
- Article: ANNALS OF MEDICINE. 2001;33(8):526-533
- Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2001;12(2):289-296
- Article: AMERICAN JOURNAL OF PATHOLOGY. 2000;157(6):1905-1916
- Show more
All other publications
- Review: FRONTIERS IN ENDOCRINOLOGY. 2018;9:409
- Corrigendum: PLOS ONE. 2015;10(5):e0126079
- Corrigendum: DEVELOPMENTAL DYNAMICS. 2012;241(2):431
- Corrigendum: JOURNAL OF CLINICAL INVESTIGATION. 2012;122(2):780
- Review: NATURE REVIEWS NEPHROLOGY. 2009;5(8):463-468
- Review: TRENDS IN MOLECULAR MEDICINE. 2007;13(9):396-403
- Editorial comment: CELL. 2006;125(2):221-224
- Review: NEW ENGLAND JOURNAL OF MEDICINE. 2006;354(13):1387-1401
- Review: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2006;17(3):813-822
- Published conference paper: KIDNEY INTERNATIONAL. 2000;58(3):972-980
Employments
- Researcher, Department of Laboratory Medicine, Karolinska Institutet, 2016-
Degrees and Education
- Docent, Karolinska Institutet, 2013